168results about "Skin implants" patented technology

A system and method for controlling clinical soiling is provided. The system includes a device cover formed from a flexible polymer sheet defining an interior volume for a skin grafting device and including at least a first opening configured to receive a portion of the skin grafting device. The system further includes a band including a gasket secured to an outer periphery of the first opening of the device cover, the gasket configured to secure the device cover to the skin grafting device around the first opening and to inhibit infiltration of fluids into the interior volume of the device cover during a skin grafting process using the skin grafting device.

Provided is a bioelectrode having excellent mechanical and chemical durability as well as excellent air permeability and flexibility, and specifically, the bioelectrode includes: a nanofiber elastic mesh sheet including a polymer nanofiber formed by electrospinning; a first metal nanowire network which is embedded on the nanofiber elastic mesh sheet, but is at least partially exposed to the outside; and an uneven layer resulting from a second metal which is placed on the first metal nanowire network exposed to the outside.

A structure of aligned (e.g., radially and / or polygonally aligned) fibers, and systems and methods for producing and using the same. One or more structures provided may be created using an apparatus that includes one or more first electrodes that define an area and / or partially circumscribe an area. For example, a single first electrode may enclose the area, or a plurality of first electrode(s) may be positioned on at least a portion of the perimeter of the area. A second electrode is positioned within the area. Electrodes with rounded (e.g., convex) surfaces may be arranged in an array, and a fibrous structure created using such electrodes may include an array of wells at positions corresponding to the positions of the electrodes.

This invention relates to a curved needle for the injection of dermal fillers into the lips and perioral area.

The utility model discloses a skin extrusion / ink-jet composite printing device, which belongs to the technical field of biological tissue printing and comprises a computer, a three-dimensional motion system, an ink box, an ink-jet printing head, an extrusion printing head, a temperature control substrate, an air pump and a pressure controller. The ink box is installed on the ink-jet printing head, and the ink-jet printing head and the extrusion printing head are installed on the three-dimensional motion system. The pressure controller is mounted on the air pump; the pressure controller is in air connection with the ink box and the extrusion printing head; the computer is electrically connected with the three-dimensional motion system, the ink-jet printing head and the pressure controller. The computer is used for controlling the three-dimensional motion system to move and further used for controlling ink jet of the ink jet printing head and controlling the pressure controller to output the air pressure value. The personalized skin printing device provided by the utility model is low in manufacturing cost and high in efficiency.

The present invention provides a skin in-situ printing device for applying biological glue and a cross-linking agent to a predetermined part of a patient, and has the following characteristics: a platform device for carrying and rotating a patient; a print head device for applying the biological glue and the cross-linking agent to a predetermined part, and having a bracket unit and a nozzle unit arranged on the bracket unit; a coating power device for providing power to squeeze the biological glue and the cross-linking agent out of the nozzle unit during coating; a three-axis moving device for driving the print head device to move to a predetermined part; and a control device for controlling the above-mentioned devices, wherein the nozzle unit has a first nozzle assembly including a first barrel and a first needle and a second nozzle assembly including a second barrel and a second needle, the second barrel and the second needle respectively surround the first barrel and the outside of the first needle and have a first gap and a second gap, the first gap is connected to the second gap, and the lower end of the second needle is lower than the lower end of the first needle.

A packaging system (10b) is provided that includes a packaging body defining a cavity (14b) and a seal (18b) configured to be joined to the packaging body to fluidly seal the cavity. The packaging system may also include at least one tissue cradle (16b) configured to be disposed within the cavity. A cavity having a single size may be configured to accommodate differently sized tissue cradles. In addition to the cavity the packaging system may include one or more additional reservoirs configured for holding a volume of liquid. Such packaging systems may be used in the storage of wet-preserved or dry-preserved human or animal tissue. Also provided are a packaged tissue specimen and a method for packaging tissue.

The invention discloses a multi-scale artificial dermal scaffold and a preparation method thereof, and belongs to the technical field of tissue engineering and biomedical materials. The artificial dermal scaffold is of a three-dimensional porous structure formed by microfilaments of a first frame and a second frame, the microfilaments of the second frame are distributed in pores of the first frame, disordered microfilaments which do not affect the penetrability of the macropores are arranged in the macropores in the top surface of the first frame, and longitudinally aligned microfilaments are arranged in the micropores in the section of the first frame. Through the specific structure, the adhesion, proliferation and migration effects of cells can be remarkably improved, and rapid vascularization of artificial dermis is facilitated. In addition, the preparation process of the artificial dermal scaffold is simple and easy to operate, can be used for batch preparation, and has a good application prospect.

The present invention relates to a dental / medical device that comprises poly(dioxanone) (PDO or PDS), preferably has an absorbent synthetic film exhibiting a color from white to grey, and is applied in the medical and dental fields. The dental / medical device may have stem cells and graphene used for inducing tissue reconstruction and / or inducing tissue regeneration of bone defects and other connective tissues (such as gingiva, skin, cartilage, cornea, etc.). Further, the present invention relates to the use of the device for the related applications described above and a method for manufacturing the device.

Systems and methods are disclosed that include determining medical treatment parameters based on a desired appearance. The system includes a camera, a display, and a processing system. The system may also include a projection device or system. The camera may capture one or more digital images of a body part of a subject. The display may display one of the digital images captured by the camera and allow inputs through a touchscreen user interface that alter a characteristic of the body part of the subject based on a desired appearance of the subject. The processing system may analyze the inputs and the desired appearance of the subject to calculate a medical treatment designed to achieve or to correspond to the desired appearance in the subject.

The present invention relates to a bioresorbable implantable device comprising a base structure comprising at least one base layer (10) comprising: • - an assembly A (1A) comprising a layer of a plurality of elongate elements A1 (1A1) which are oriented in a longitudinal direction LA1, and a layer of a plurality of elongate elements A2 (1A2); an assembly B (1B) comprising a layer of a plurality of elongate elements B1 (1B1) which are oriented in a longitudinal direction LB1, and a layer of a plurality of elongate elements B2 (1B2); • - the assembly B (1B) is placed at least partially on top of the assembly A (1A); • - the direction LA1 intersects the direction LB1; and • - the base structure comprises a plurality of base layers placed at least partially one on top of the other.

The present invention provides a skin in-situ printing device for applying bio-glue and cross-linking agent to a predetermined part of a patient, and has the following characteristics, including: a platform device for carrying and rotating a patient; a print head device having a support unit and a nozzle unit; a storage device including a first storage device and a second storage device; a coating power device for providing coating power to the storage device; a three-axis moving device for driving the print head device to move to a predetermined part; and a control device, wherein the nozzle unit has a first nozzle and a second nozzle, the first nozzle has a first tube portion and a first nozzle head portion, the two ends of the first tube portion are respectively connected to the first storage device and the first nozzle head portion, the second nozzle has a second tube portion and a second nozzle head portion, the two ends of the second tube portion are respectively connected to the second storage device and the second nozzle head portion, the second nozzle extends and passes through the tube wall of the first tube portion, so that the second nozzle head portion is located at the central axis position of the inner cavity of the first tube portion.

The harvesting of hair for a hair transplant procedure with immediate placement of the hair grafts to the balding area, employs a hollow drill connected to a suction with an imaging system (containing one or more cameras) which permits alignment of the center of the cutting edge of the needle on or slightly offset from the axis of the hair within the follicular unit to be removed. This harvesting tool may be robotically controlled. As each follicular unit may have more than one hair, the surgeon controls the number of hairs in each graft he wishes to remove, excising the graft one at a time. A special FUE tool is used that excises the entire follicular unit with minimal residual attachments. The tool utilizes vacuum to facilitate complete excision. The graft that is excised is sucked though tubing and almost instantaneously delivered to an implanter held by the surgeon (Duplex Implanter) or by a robot. This graft on Demand system is controlled by the surgeon through a series of commands to the handpiece of the implanter for one, two, three or more hair grafts. The excision needle (punch) is placed to remove a hair graft with the chosen number of hairs, taken from an area which has been previously mapped out. When properly aligned, a follicular unit is removed without damaging critical anatomical portions of the follicles and it is delivered to the implanter at the command of the surgeon. In one embodiment, a movable x / y / z stabilizing gantry is employed to position the hollow needle in each instance which can be manually controlled by the surgeon, or robotically controlled with one or more robots. In another embodiment, a computer maps out the location of every graft within the surgical field of view, in part or in whole, and selects those follicles, minimizing the spacing left remaining after each excision while obtaining the number of grafts targeted by the surgeon. In still another embodiment, one or more robotic arms, controlled automatically by a controller or manually by a surgeon, operate graft excision instruments to facilitate speed and accuracy of the excision process.

Provided herewith is a needle for delivering dermal filler thread to a wrinkle in a patient. The needle can also be used to deliver the thread to a patient for the purposes of facial contouring. The needle comprises a coupler for attaching the thread to the needle and also a trocar to ease delivery through the skin.

The specification relates to a method of manufacturing a diabetic foot patient-specific skin regeneration sheet, and a diabetic foot patient-specific skin regeneration sheet.

To provide a tissue filler that allows a host cell to quickly get into the tissue filler and also allows the host cell to be engrafted in it, and has sufficient mechanical strength.SOLUTION: A tissue filler includes porous collagen sponge including a honeycomb structure inside it, and fibrillar collagen contained in the lumen of the honeycomb structure.SELECTED DRAWING: Figure 1

A universal biological prosthesis of acellular dermal matrix (ADM) intended for use in body reconstruction processes and method of manufacture. A universal biological prosthesis of acellular dermal matrix (ADM) intended for use in body reconstruction processes, comprising: a first layer of ADM of biological origin arranged inferiorly to delimit a cavity with a lower edge; a filling material disposed in the cavity surrounded by the first layer of ADM consisting of a ground ADM having the consistency of a fibrous paste; and a second layer of ADM of biological origin arranged on the upper part covering the filling material and whose upper edge rests peripherally on the lower edge of the first layer of ADM, thus defining a rim;where the first layer of ADM and the second layer of ADM are joined by an eyebrow overlap along the upper edge of the first layer of ADM with the lower edge of the peripheral rim using a biocompatible adhesive, or by absorbable suture; where the first layer of ADM, the second layer of ADM and the ADM filling material are not immunogenic; and where the ADM comprises collagen fibers, fibronectin, elastin, laminin, glycosaminoglycans and hyaluronic acid. Method for its manufacture.

An extraction device, including a motor, a driveshaft operatively coupled to the motor and driven to rotate thereby, a punch tool directly coupled to a distal end of the driveshaft to rotate therewith, and arranged to be in physical contact with a skin layer during operation of the extraction device, a force sensor operatively coupled to the driveshaft to measure a force exerted thereupon by the skin layer, and a controller communicatively coupled to the motor and to the force sensor. The controller is configured to define multiple rotary modes and multiple multiphasic modes, each multiphasic mode including at least two rotary modes, receive a selection of a multiphasic mode, and provide, based on the selection, a control signal to the motor instructing the motor to operate in the multiphasic mode.

The present invention relates to the technical field of burn patches, and particularly to a burn patch for treating skin wounds and a preparation method thereof. The method includes: dissolving the active ingredients and the collagen into a solvent using a stirrer to output a mixed solution; bonding the silica gel with the nylon textile fabric to output a film patch; coating the mixed solution on one side of the nylon textile fabric of the film patch; drying the film patch coated with the mixed solution using a hot air circulation oven; cutting the dried film patch using a cutting machine; punching holes on the silica gel side of the cut film patch to output a burn patch; determining the preparation stability of the burn patch based on the variance of the concentration of the mixed solution; if the preparation stability does not meet the requirements, adjusting the rotation speed of the stirring motor of the stirrer; if the forming effectiveness does not meet the requirements, adjusting the tool feed of the cutting machine. The present invention improves the preparation stability of the burn patch.

A hair implant having an anchor comprising an anchor body, and at least one collagen receiving structure selected from the group of at least one tunnel through the anchor body or an anchor body external surface feature. The anchor includes at least one hair strand projecting from an anchor body distal end and may include a bend, wherein the at least one collagen receiving structure, or the external surface feature, support collagen ligature growth after hair implant implantation for anchoring in the recipient. The hair implant includes a two-part construction having a base module formed of the anchor body and at least one hair stem for coupling with a long hair strand. Another alternative includes a hair strand first end that is passed through the skin, underneath and then up through the skin at another location to result in the hair strand having two portions projecting from the skin surface.

To provide an implantable inflatable device.SOLUTION: An implantable inflatable device (100) includes a fluid reservoir (110) defining a cavity, an inflatable member (150), a pump assembly (130) configured to transfer fluid from the fluid reservoir to the inflatable member, and a programmable control module. The programmable control module is configured to activate the pump assembly to transfer fluid from the fluid reservoir to the inflatable member.SELECTED DRAWING: Figure 1

An apparatus includes a flexible container and a port. The container includes a first layer coupled to a second layer to define a storage volume within which a tissue specimen can be contained. The first layer has a first stiffness and the second layer has a second stiffness. An edge of the first layer is spaced apart from an edge of the second layer to define an opening into the storage volume. The edges of the first and second layer form a peelable seal that hermetically seals the storage volume such that the first layer can be peeled away from the second layer to expose the storage volume. The port is coupled to the flexible container and allows fluid communication between the storage volume and an external volume.

The invention provides a method for preparing a skin graft composition comprising (a) obtaining, from a subject requiring a skin layer patch or dressing, a skin sample, (b) placing the skin sample in a container with a sterile medium, (c) separating fibroblasts and keratinocytes from the skin sample to obtain a solution comprising fibroblasts and keratinocytes or reshaping and resizing the skin sample to obtain a solution comprising the reshaped and resized skin sample, and (d) combining the fibroblasts and the keratinocytes with a matrix to thereby form a skin graft composition. The invention also provides a method for providing a skin graft composition to a subject, as well as a method of providing a skin layer patch or dressing, or a skin graft, to a subject in need thereof.

Systems and methods for hair transplantation using a hair transplantation device are provided. The hair transplantation device includes an extraction unit including a coring needle configured to extract at least one hair follicle from a donor site; an implantation unit removably coupled to the extraction unit, the implantation unit including a splitting needle configured to create an opening in a recipient site; a housing coupled to the extraction unit; and a user interface extending from the housing and movable relative to the housing. The user interface includes a pin movable within the coring needle relative to the housing.

A hair implant suitable for subcutaneous implantation comprises (a) an anchor comprising: (i) an anchor body and (ii) at least one collagen receiving structure comprising at least one a tunnel disposed through the anchor body. The hair implant further comprises: (b) at least one hair element projecting from a distal end of the anchor body, wherein the hair implant is unitary in structure. The at least one collagen receiving structure is configured to support collagen ligature growth after subcutaneous implantation of the hair implant so as to anchor the anchor to a hair implant recipient.

There is provided a device for skin bioprinting and a method of making a device for skin bioprinting, the device comprising: a dispenser module configured to actuate and dispense a bioink from a first chamber, and to actuate and dispense a crosslinker from a second chamber: a storage module coupled to the dispenser module, the storage module comprising the first chamber for storing the bioink and the second chamber for storing the crosslinker; a mixing module coupled to the storage module for mixing the bioink and the crosslinker dispensed from the first and second chambers respectively; and a rotatable applicator coupled to the mixing module for rotatably applying a mixture of the bioink and crosslinker from the mixing module onto a surface of a patient in need of skin regeneration.

The present disclosure relates generally to tissue container systems and kits that find use in the transport of tissues and methods of using the tissue container systems. In particular, systems and kits that support the transport, thawing and use of cryopreserved human skin equivalents, and methods of their use by a health care provider are provided.

The present invention provides a skin in-situ printing device, which is used for applying biological glue and crosslinking agent to a predetermined part of a patient to form artificial skin by printing, and has the following characteristics, including: a platform device, which is used to carry and rotate the patient; a print head device, which is used to apply the biological glue and crosslinking agent to the predetermined part, and has a bracket unit and a nozzle unit arranged on the bracket unit; a coating power device, which is used to provide power for the biological glue and crosslinking agent to be squeezed out of the nozzle unit during coating; a three-axis moving device, which is used to drive the print head device to move to the predetermined part; and a control device, which is used to control the above devices to cooperate with each other, wherein the nozzle unit has a first nozzle assembly for accommodating and applying the biological glue and a second nozzle assembly for accommodating and applying the crosslinking agent, the first nozzle assembly includes a first barrel and a first needle, the second nozzle assembly includes a second barrel and a second needle, and the first needle and the second needle are parallel to each other.