119 results about "Gastric fluid" patented technology

The invention discloses a self-power-generation stomach residence electronic capsule and application thereof, and belongs to the technical field of medical capsules, the self-power-generation stomach residence electronic capsule structurally comprises a capsule shell, and a self-power-generation stomach residence unit, a drug release unit and a circuit system which are arranged in the capsule shell; the self-generating stomach residence unit structure comprises an anode, a plurality of elastic support arms, a cathode and a fastener, and the fastener fixes the plurality of elastic support arms between the anode and the cathode; the anode and the cathode are subjected to primary battery reaction in a gastric juice environment to generate power; the drug release unit is detachably connected with the self-generating gastric residence unit, the drug release unit comprises a drug cabin and a propelling module, the propelling module comprises an electrolyte, an isolating membrane and a propellant, the isolating membrane plays a role in isolating the electrolyte and the propellant and can be dissolved by the electrolyte under the condition that voltage is applied, and the drug cabin is connected with the drug cabin. After the electrolyte is in contact with the propellant, pushing force is generated to release the medicine in the medicine cabin.

The invention belongs to the technical field of preparation of biological materials, and particularly discloses a sea cucumber flower self-assembled polypeptide-iron nano-carrier as well as a preparation method and application of the sea cucumber flower self-assembled polypeptide-iron nano-carrier. The preparation method comprises the following steps: dissolving freeze-dried sea cucumber flower powder in deionized water, adjusting the pH value to be alkaline, heating and stirring, centrifuging, discarding the precipitate, adjusting the pH value to be acidic, centrifuging, collecting the precipitate, and freeze-drying to obtain sea cucumber flower protein powder; preparing a reaction solution, adding simulated gastric juice and simulated intestinal juice, stirring for reaction, inactivating protease, centrifuging, taking supernatant, and freeze-drying to obtain sea cucumber flower self-assembled polypeptide; the preparation method comprises the following steps: preparing a solution from sea cucumber, adding FeCl2. 4H2O and ascorbic acid, adjusting the pH value to be acidic, carrying out heating reaction, centrifuging, discarding the supernatant, and freeze-drying to obtain the sea cucumber flower self-assembled polypeptide-iron nano-carrier. The invention discloses a sea cucumber flower self-assembled polypeptide-iron nano-carrier as well as a preparation method and application thereof. The carrier can promote absorption of an organism to iron, a relatively high iron ion release rate is maintained in an intestinal environment, and the in-vivo bioavailability of iron ions is improved.

The invention discloses a sea cucumber flower self-assembled polypeptide-selenium nano-carrier with antioxidant activity and a preparation method and application thereof, belongs to the technical field of functional protein peptides, and particularly relates to a preparation method of the sea cucumber flower self-assembled polypeptide-selenium nano-carrier with antioxidant activity, which comprises the following steps: heating a sea cucumber flower protein solution; the preparation method comprises the following steps: mixing sea cucumber with simulated gastric juice, reacting for 30-150 minutes, then adding simulated intestinal juice, reacting for 20-120 minutes, carrying out enzyme deactivation treatment, centrifuging, taking supernate, and freeze-drying to obtain sea cucumber flower self-assembled polypeptide; and mixing the sea cucumber flower self-assembled polypeptide with deionized water to prepare a sea cucumber flower self-assembled polypeptide solution, mixing the sea cucumber flower self-assembled polypeptide solution with a sodium selenite solution and a phosphate buffer solution, reacting for 20-60 minutes, washing with an ethanol solution, centrifugally collecting precipitate, and freeze-drying to obtain the sea cucumber flower self-assembled polypeptide-selenium nano-carrier. The sea cucumber flower self-assembled polypeptide-selenium nano-carrier prepared by the invention has good antioxidant activity and potential of effectively delivering selenium to an organism.

The invention provides a visual stomach tube convenient for guide wire traction adjustment, which comprises a stomach catheter for feeding, a visual sleeve for visualization is sleeved at the bottom end of the stomach catheter, a traction wire connected with the visual sleeve is arranged in the stomach catheter in a penetrating manner, one side of the stomach catheter is connected with a shunt tube, the other end of the shunt tube is connected with a filter sleeve, and the filter sleeve is connected with a guide wire. A conductive wire is embedded in the stomach catheter, the traction wire is hollow, a wire set used for signal transmission and power supply is connected to the middle of the traction wire in a penetrating mode, and a filling cavity is formed in the bottom end of the stomach catheter. The stomach tube can be prevented from entering the trachea by mistake, meanwhile, after use is completed, gastric juice is extracted synchronously for inspection, operation steps are reduced, meanwhile, the visual sleeve and the guiding traction wire can be recycled, the overall use cost is reduced, and the burden of a patient is reduced.

The present invention discloses a nasogastric feeding device for nursing the digestive tract with anti-backflow, which relates to the field of nasogastric feeding technology, including a feeding device and a hose, wherein the feeding device includes a driving rod and a housing, the upper and lower ends of the housing are respectively provided with end caps and a sleeve, a pressing plate and a mesh plate are installed inside the housing, a cavity is formed between the end cap and the sleeve, a four-way pipe is installed on the end cap, an air pump and a control valve are installed inside the four-way pipe, the pressing plate and the mesh plate are provided with a driving rod, and the four ports of the four-way pipe are respectively connected to the external environment, the cavity, the air pump and the space inside the housing. The present invention performs air extraction before food processing to prevent the liquid food from carrying a large amount of air into the patient's stomach during the infusion period, thereby preventing the patient from experiencing bloating. At the same time, the hose is provided with an anti-backflow mechanism to prevent the phenomenon of gastric fluid backflow due to the patient's body posture.

This invention belongs to the field of microbial technology, specifically relating to a strain of *Pediococcus pentosaceus* SUN02 with acetylcholinesterase inhibitory activity and its applications. This *Pediococcus pentosaceus* SUN02 is deposited at the China General Microbiological Culture Collection Center (CGMCC) with accession number CGMCC No. 29705. The *Pediococcus pentosaceus* SUN02 provided by this invention exhibits strong acid and bile salt resistance, good tolerance in simulated gastric and intestinal fluids, and can successfully reach the human intestine. *Pediococcus pentosaceus* SUN02, in its bacterial suspension and inactivated cells, possesses strong acetylcholinesterase inhibitory activity, produces γ-aminobutyric acid (GABA), and has antioxidant and other probiotic functions. Its application in probiotic products may help improve Alzheimer's disease, enhance learning and memory abilities, regulate mood, and improve sleep.

The invention discloses a reversible regulation coordination type rare earth nanocrystal-organic dye, which comprises a rare earth nanocrystal and a cyanine dye, the cyanine dye forms reversible coordination with the rare earth nanocrystal on the surface of the rare earth nanocrystal, the cyanine dye has a structure shown as a formula I: # imgabs0 #, and R is halogen or a group # imgabs1 # * represents a bonding position. The reversible regulation coordination type rare earth nanocrystal-organic dye can be subjected to reversible coordination, the structure of the organic dye is not damaged, continuous detection can be performed, the detection sensitivity is relatively high, and the anti-interference capability is strong. The invention also discloses a preparation method of the reversible regulation coordination type rare earth nanocrystal-organic dye, a luminescent probe, application of the luminescent probe in biological detection, and a method for detecting the pH value of gastric juice by using the luminescent probe.

The invention relates to the technical field of biological medicine, and discloses bifidobacterium adolescentis YF-01 and application thereof in fermented milk. The bifidobacterium adolescentis YF-01 is separated from adult excrement and is preserved in the China Center for Type Culture Collection, and the preservation number is CCTCC NO: M 20251308. Experiments prove that the bifidobacterium adolescentis YF-01 has good gastrointestinal fluid tolerance, the survival rate of the bifidobacterium adolescentis YF-01 can reach 90.1% after simulated gastric fluid treatment for 3 h, and the survival rate of the bifidobacterium adolescentis YF-01 can reach 72% after simulated intestinal fluid treatment for 4 h The strain has the self-aggregation rate of 88.83% and the hydrophobicity of 79.41%, has remarkable scavenging capacity on DPPH free radicals and hydroxyl free radicals, shows good antioxidant activity and adhesion capacity, and provides a theoretical basis for application of the strain in fermented milk. The strain and metabolites thereof can be used for preparing food, medicines or health care products capable of regulating intestinal flora and enhancing oxidation resistance, and have remarkable application potential in development of functional fermented milk products.

The invention provides a pet hair decomposer with synergistic effect of bacillus subtilis and keratinase, the pet hair decomposer comprises bacillus subtilis ZYpet-015 and keratinase, the preservation number of the bacillus subtilis ZYpet-015 is CGMCC (China General Microbiological Culture Collection Center) No.34790, and the preservation date is June 6, 2025; the protease activity of the bacillus subtilis is greater than or equal to 129.92 U, the survival rate of the bacillus subtilis in simulated gastric juice within 3 hours is greater than 50%, and the tolerance rate of the bacillus subtilis in intestinal juice within 4 hours is greater than 90%. According to the pet hair decomposing agent, hair keratin is synergistically degraded through protease secreted by the bacillus subtilis ZYpet-015 and keratinase, and the hair decomposing efficiency reaches 28.07% + / -2.79% and is remarkably higher than that of a single treatment group. Meanwhile, experiments prove that the pet hair decomposer can effectively destroy the hair cuticle structure, is suitable for a pet hair-melting nutritional supplement and can relieve the hair ball symptom.

The invention relates to the technical field of microorganisms, in particular to lactobacillus plantarum, selenium-rich lactobacillus plantarum and application thereof. The lactobacillus plantarum with the preservation number of GDMCC No: 64006 is provided, selenium is enriched through the lactobacillus plantarum, and inorganic selenium is converted into biological nano-selenium which can be preserved in vivo for a longer time. The invention provides a technical scheme that lactobacillus plantarum is subjected to selenium-enriched culture to prepare the selenium-enriched lactobacillus plantarum, the elimination capability of the prepared selenium-enriched lactobacillus plantarum to free radicals DPPH and ABTS < + > and the endurance capability of the prepared selenium-enriched lactobacillus plantarum to simulated gastric juice can be remarkably improved, and the tolerance of the prepared selenium-enriched lactobacillus plantarum to cholate and simulated artificial intestinal juice cannot be reduced; meanwhile, the AIEC associated colitis can be relieved from the aspects of accelerating weight recovery, reducing colon tissue pathological damage, reducing AIEC colonization, promoting intestinal barrier repair, reducing the proinflammatory factor level, improving the selenium level, improving intestinal flora disorder and the like.

This application relates to the field of functional composition technology, and in particular to a GABA-vitamin D neuroprotective composition and its preparation method, comprising medium-chain triglycerides, modified phospholipids, and a GABA-vitamin D blend. This application utilizes the low interfacial tension and strong amphiphilic compatibility of medium-chain triglycerides and modified phospholipids, enabling them to be miscible with the blend, thus improving the characteristics of GABA and vitamin D being easily degraded and oxidatively inactivated under complex physiological environments, and solving the problems of poor stability and asynchronous absorption. In the preparation method, the preferred component mass ratio is (0.6–1.5):1:(1–1.6), and mixing is carried out at 50–80°C for 10–60 min. The resulting system features high encapsulation efficiency, uniform particle size distribution, and high bioavailability. After treatment in simulated gastric fluid (pH 1.2) for 2 hours, the average GABA retention rate is ≥88% (optimal up to 94.3%), and the average vitamin D retention rate is ≥94% (optimal up to 96.8%). After treatment in simulated intestinal fluid (pH 6.8) for 4 hours, the simultaneous release rate of GABA and vitamin D is ≥90%, achieving precise intestinal delivery and making it suitable for industrial production.

The invention relates to a microbial single-cell gelation encapsulation method based on aloe gel and application, the method realizes single-cell gelation encapsulation through electrostatic interaction of sterile aloe gel and intestinal anaerobic bacteria (such as Agathobacter rectasis), and the method comprises the specific steps of aloe gel preparation, bacterial suspension culture and oscillation mixing to form a stable structure. The preparation method has the advantages that the acid resistance and biocompatibility of the natural aloe gel are utilized to replace a traditional synthetic material, so that the gastrointestinal tolerance of thalli is improved; meanwhile, the synergistic effect of aloe active ingredients (such as aloe-emodin) and intestinal bacterial metabolites (butyric acid) is combined, so that the anti-inflammatory and intestinal steady-state regulation and control effects are enhanced. Experiments show that the survival rate of the encapsulated bacteria in simulated gastric juice within 4 hours is larger than or equal to 90%, the intestinal colonization rate is effectively increased compared with naked bacteria, the inflammatory factor level of a colitis model mouse can be remarkably reduced, and a safe and efficient new strategy is provided for micro-ecological treatment of inflammatory bowel diseases.

The present invention relates to a stable oral liquid pharmaceutical composition of celecoxib or pharmaceutically acceptable salts thereof. The celecoxib present in the compositions as described herein do not show any precipitation when subjected in Fasted-State Simulated Gastric Fluid (FaSSGF) at pH 2.0, temperature of 37° C.±0.5° C. and under stirring at a speed of 50 rpm at least for 60 minutes. It also relates to the process of preparing and method of using said composition of celecoxib.

The present invention relates to the field of microbial technology, and provides a Pediococcus acidilactici YYS-J2 that can degrade acrylamide and produce high levels of phenyllactic acid, and its application. Pediococcus acidilactici The preservation number of YYS-J2 is CGMCC No. 28183. This *Pediococcus lactis* YYS-J2 exhibits excellent acrylamide removal capacity, high efficiency in L-phenylalanine utilization and metabolism, high-quality phenyllactic acid production capacity, and excellent *Streptococcus mutans* antibacterial activity. It also produces superoxide dismutase (SOD) and shows good tolerance in simulated gastric and intestinal fluids. This *Pediococcus lactis* YYS-J2 can provide a new probiotic source for the development of functional products such as acrylamide removal products, antibacterial products, and SOD-producing products, and has significant application value.

The invention discloses a composite particle with a prebiotic function and colon-targeted co-delivery performance as well as a preparation method and application thereof, and belongs to the technical field of functional foods and intestinal micro-ecological regulators. According to the composite particle, the curcumin and the resveratrol are encapsulated by the peanut protein isolate to form a nano core, the outer layer of the nano core is a composite shell layer composed of the carboxymethyl konjac glucomannan and the prebiotics, a stable core-shell structure is formed, and the composite particle is small in particle size, good in dispersity and stability and good in stability. The stability of a protein-based delivery system in a gastrointestinal tract environment can be obviously improved; the release rate of the composite particles in simulated gastric juice and intestinal juice is low, and the composite particles can be specifically degraded and release active ingredients in simulated colon fluid containing beta-mannase, so that colon-targeted co-delivery can be realized. The composite particle disclosed by the invention is simple in preparation process and stable in function, can be applied to the fields of functional foods, health foods, formula foods for special medical purposes and the like, realizes dual purposes of active component delivery and intestinal microenvironment regulation, and has a wide application prospect.

The invention relates to a colon-targeted micro-ecological regulation composition. The colon-targeted micro-ecological regulation composition is prepared by compounding the following functional components in percentage by weight: 5-95% of a component A, 1-15% of a component B and 4-94% of a component C, the component A is resistant starch, the polymerization degree DP is greater than or equal to 15, and the crystallinity is greater than or equal to 35%; the component B is probiotics and is embedded through a complex coacervation method or an extrusion-gel method, the embedding rate is larger than or equal to 75%, and the particle size is 200-800 microns; the survival rate is greater than or equal to 60% after treatment in simulated gastric juice for 2 hours, and the survival rate is greater than or equal to 50% after treatment in simulated intestinal juice for 4 hours; the component C comprises functional nutritional auxiliary materials, the functional nutritional auxiliary materials comprise prebiotics and a medicinal and edible composition, and the prebiotics comprise rapid fermentation type prebiotics, medium-speed fermentation type prebiotics, slow fermentation type prebiotics and a non-fermentation type water-holding expansion component. By constructing a carbon source slow release-flora orientation-metabolism regulation ternary interaction collaborative network, accurate regulation and multi-target metabolism intervention of the whole digestive tract are realized.

This invention discloses a selenium-enriched dairy product from selenium-enriched dairy cows and its preparation method, comprising the following components and process characteristics: Basic milk matrix: by mass percentage, containing 85-95% raw milk or reconstituted milk, 0.5-2% milk protein concentrate, and 0.1-0.5% fructooligosaccharides; Probiotic-polyphenol complex: composed of *Lactobacillus plantarum* LP-33 (preservation number CGMCC No. 24567) and grape seed polyphenols, wherein the polyphenols are compounded in a 1:1 ratio with zein-chitosan bilayer microencapsulated form in a free state, with a total addition amount of 50-100 mg / L; Dynamic pH control system: during fermentation, the pH value is monitored in real time and a 0.1-0.5 mol / L sodium bicarbonate buffer solution is automatically added to maintain the pH at 5.0-5.5. This invention achieves breakthroughs in viable count and acid resistance; through dynamic pH control and synergistic protection by polyphenols, the viable count of the finished product is ≥1×10⁻⁶. 9 With a CFU / mL concentration, the survival rate of probiotics in simulated gastric juice for 2 hours is >80%, solving the problem of "high output but low intake" of probiotics in traditional fermentation.

The invention relates to the technical field of medical instruments, in particular to a portable multi-channel glottis cover. Comprising an external cylinder, the external cylinder is fixedly connected with an air guide pipe, the external cylinder is fixedly connected with a flow guide pipe, the flow guide pipe is fixedly connected with an inflator pump, and the inflator pump is provided with a flow blocking unit; the flow blocking unit comprises first protruding rings distributed at intervals, the first protruding rings distributed at intervals are communicated with the inflator pump, and the inflator pump is communicated with second protruding rings distributed at intervals. Through the shape design and staggered arrangement of the first convex rings and the second convex rings, a plurality of annular cavities with opposite volume changes are formed in cooperation with the esophagus of a patient, when the first convex rings and the second convex rings are extruded by reflux gastric juice, the directions of counter-acting force provided by the adjacent annular cavities after the adjacent annular cavities are pressed are different, and the counter-acting force is uniform. The counter-acting force in different directions can effectively disperse external force, the deformation quantity of the first convex ring and the second convex ring is reduced, and therefore the probability of sealing failure is reduced.

The present invention discloses a magnetically guided sampling capsule robot and a sampling method, which relate to the technical field of capsule robots. A first capsule shell and a second capsule shell interlock to form an internal cavity. An internal magnet is located in the internal cavity. A first soft magnetic film and a second soft magnetic film are located on either side of the internal magnet. In the absence of an external magnetic field, the first soft magnetic film and the second soft magnetic film both protrude toward the internal magnet. A first sampling hole is provided on the first capsule shell, forming a first sampling cavity between the first capsule shell and the first soft magnetic film. A second sampling hole is provided on the second capsule shell, forming a second sampling cavity between the second capsule shell and the second soft magnetic film. The present invention is used for sampling gastric fluid and / or mucosa at a lesion site, can achieve anchored sampling under the action of an external magnetic field, and can achieve a single gastric entry and multiple sampling operations through the design of the symmetrically arranged first and second sampling cavities.

The invention discloses a negative pressure gastric lavage device for pediatric medicine, and relates to the technical field of gastric lavage devices, the negative pressure gastric lavage device comprises a machine body and a suction mechanism, one side of the machine body is provided with a controller, and the other side of the machine body is provided with a storage tank and a collection tank. According to the negative-pressure gastric lavage device for the pediatric department, purified water is injected into the storage tank through the water adding pipe, and along with rising of the water level in the storage tank, a floating plate can drive a rack rod to be meshed with a transmission gear, so that a transmission shaft on one side of the transmission gear is driven to rotate, and a rubber sleeve and a connecting ball connected with one end of the transmission shaft also rotate; when the stirring rod rotates, the connecting ball can feed liquid medicine in the medicine feeding cavity into the medicine spraying mechanism through the conveying pipe, quantitative adding of the liquid medicine is completed, when the stirring rod rotates, the medicine spraying mechanism can evenly feed the liquid medicine into the storage tank, gastric lavage liquid can be evenly fed into the stomach of a child through the suction mechanism, impurities in the stomach are completely pumped out, and gastric lavage is completed.

The invention relates to a separation type critical patient liquid diet feeding device which comprises a main box body, a first storage cavity and a second storage cavity are formed in the main box body, a connecting base and a Y-shaped three-way pipe are installed outside the main box body, and a first pipe cavity and a second pipe cavity are formed in the connecting base. One end of the first tube cavity and one end of the second tube cavity are communicated with two branch tubes of the Y-shaped three-way tube respectively, the other end of the first tube cavity and the other end of the second tube cavity are communicated with the first storage cavity and the second storage cavity respectively, and a main tube of the Y-shaped three-way tube is connected with a stomach tube communicated with the stomach led into a patient. An opening and closing piece used for adjusting the first pipe cavity and the second pipe cavity to be closed or opened is movably installed in the connecting base, pushing pressure is generated in the first storage cavity, so that liquid food is conveyed, liquid food feeding operation of a patient is facilitated, meanwhile, regurgitated gastric juice of the patient is conveniently pumped into the second storage cavity, and the patient can conveniently feed the liquid food. And the first storage cavity and the second storage cavity do not interfere with each other under the action of the opening and closing piece, so that pollution caused by liquid food storage is avoided.

The present invention discloses an enteric-coated lignin bacterial embedding particle for treating ulcerative colitis and its preparation. Based on the principle of electrostatic interaction, the present invention uses anionic lignin to embed bacteria. Under neutral or weakly alkaline conditions, the surface of the bacteria carries a negative charge. Through electrostatic interaction, a layer of Ca<supgt;2+< / supgt; is adsorbed on the surface of the bacteria, and then Ca<supgt;2+< / supgt; adsorbs anionic lignin to form a nano-coating on the surface of the bacteria, realizing the embedding of the bacteria. The preparation process of the enteric-coated lignin bacterial embedding particle of the present invention is simple. It not only increases the viable count of bacteria in simulated gastric juice and is smoothly released in simulated intestinal juice, but also lignin and the embedded bacteria can play a synergistic therapeutic effect, effectively treating DSS-induced colitis in mice and increasing the colon length of diseased mice, providing new ideas for the development of new oral dosage forms of bacteria, and expanding the high-value application range of lignin, promoting the development and application of biomass resources.

The utility model relates to a simulated human device applied to stomach tube and sengstaken-blakemore tube implantation, which comprises a simulated human model which is an upper human body model comprising a nasal cavity part, an oral cavity part, a throat part, an esophagus part and a stomach part, and simulated skin is arranged on the outer surface of the simulated human model; the replaceable one-way valve is arranged between the esophageal part and the cardia, is in a valve design and is used for controlling the circulation direction of the simulated gastric juice; the first pressure receptor is arranged at the lower part of the esophageal part and is used for detecting the pressure on the esophageal part after the gas injected into the gastric sac and the esophageal sac is expanded; and the second pressure receptor is arranged at the stomach base position of the stomach and is used for detecting the pressure on the stomach after the injection gas of the gastric sac and the esophageal sac is expanded. By adopting the dummy device applied to the stomach tube and sengstaken-blakemore tube implantation operation, the clinical operation process can be simulated more truly, students are helped to master key skills, and the operation accuracy and safety are improved.

The present invention relates to the field of medical auxiliary equipment, and in particular to a multifunctional gastric lavage solution preparation system, comprising a containing water tank, a water inlet pipe connected to the containing water tank is provided on one side of the containing water tank, a purification and filtering device is provided on the water inlet pipe, a liquid heating device and a water outlet pipe are provided at the bottom of the containing water tank, the liquid heating device is detachably installed on the containing water tank, the water outlet pipe is located beside the liquid heating device, a first solenoid valve and a dosing device are provided on the water outlet pipe, a holding bucket is installed on the water outlet of the water outlet pipe, a controller, an operation display screen and a temperature display are provided at the front end of the containing water tank, and the operation display screen, the temperature display, the purification and filtering device, the first solenoid valve and the dosing device are all connected to the controller. The present invention realizes automatic heating of water source, medical staff can get the heated water source at any time, and can automatically and accurately mix the medicine and add it into the holding bucket to form gastric lavage solution.

The utility model relates to the field of medical instruments, and discloses a nasal gastrointestinal tube multifunctional connector which comprises a connector body, a one-way valve is arranged at the top end of the connector body, a nutrition catheter is fixedly connected to the bottom end of the connector body, a liquid extraction gastral cavity is fixedly connected to one side of the connector body, and the liquid extraction gastral cavity is fixedly connected to the other side of the connector body. The other side of the connector body is fixedly connected with a nutrition enteric cavity, the outer wall of the nutrition catheter is provided with an external thread, the outer wall of the external thread is in threaded connection with a threaded sleeve, the outer wall of the threaded sleeve is provided with an elastic band, and the outer wall of the elastic band is fixedly connected with a first fixing piece. According to the utility model, by arranging the structures such as the external thread, the threaded sleeve, the elastic band, the fixing piece I and the fixing piece II, the connector can be adjusted and fixed beside the body of a user according to the operation convenience of a worker, so that the stability of the connector main body when gastric juice is sucked and nutrient solution is conveyed to the intestinal tract is ensured, and the stability and the safety of a pipeline are ensured.

The present invention relates to compositions in the form of cationic microemulsion preconcentrates that contain at least one lipophilic and water-insoluble active agent, at least one polyglyceryl-containing emulsifier, at least one cationic emulsifier, carrier oils, solubilizers, antioxidants, and preservatives. When contacted with either an aqueous medium, gastric or intestinal fluid, the cationic microemulsion preconcentrates self-assemble into cationic microemulsions that are stable in gastric and intestinal fluids. The invention is also related to methods of making and methods of using the cationic microemulsion preconcentrates.

Systems and methods for effecting bariatric procedures are disclosed. Each system includes an instrument, a control valve and, optionally, a suction controller. The instrument is in the form of an elongated, flexible sizing tube having a distal end portion including a plurality of apertures. The control valve enables suction to be applied to the patient's stomach via the apertures to drain gastric fluids and to bring adjacent portions of the patient's stomach into engagement the sizing tube to provide a visually perceptible delineation line along which a portion of the stomach may be resected, sealed and tested.

Systems and methods for effecting bariatric procedures are disclosed. Each system includes an instrument, a control valve and, optionally, a suction controller. The instrument is in the form of an elongated, flexible sizing tube having a distal end portion including a plurality of apertures. The control valve enables suction to be applied to the patient's stomach via the apertures to drain gastric fluids and to bring adjacent portions of the patient's stomach into engagement the sizing tube to provide a visually perceptible delineation line along which a portion of the stomach may be resected, sealed and tested.

The utility model relates to the technical field of gastroenterology department, in particular to a pressurized gastric lavage device for emergency gastroenterology department, which is provided with an independent detachable dirt storage barrel structure and is combined with a gastric lavage mechanism to form a single pipeline, so that the pressurized gastric lavage device is more portable and efficient to clean, and the practicability is improved; comprising a base, a connecting frame, a water bath mechanism, a gastric lavage liquid storage barrel, a first external thread opening, a first internal thread cover, a pressure pump, a pressure pipe, a pressure reduction pump, an air suction pipe, a second internal thread cover, a dirt storage barrel, a second external thread opening and a grip, the middle of the top end of the base is connected with the bottom end of the connecting frame, and the top end of the connecting frame is connected with the pressure pump and the pressure reduction pump; the bottom end in the connecting frame is connected with the top end of a second internal thread cover, the inner side of the second internal thread cover is detachably screwed with the outer side of a second external thread opening, the bottom end of the second external thread opening is connected with the top end of a dirt storage barrel, the middle of one side of the outer end of the dirt storage barrel is connected with the inner side of a grip, and a gastric lavage tube structure is arranged on the outer sides of the gastric lavage liquid storage barrel and the second internal thread cover.

The preparation method comprises the following steps: (1) compounding hermetia illucens larvae, whole tenebrio molitor and euphausia superba according to a mass ratio of (3-5): (2-4): 1, carrying out enzymolysis, and reacting with a yeast cell wall extract to form a glycopeptide compound; (2) coating the glycopeptide compound with a mannan oligosaccharide and chitosan solution to form microcapsules, and controlling the release rate of the microcapsules in simulated gastric juice to be lower than 30% and the release rate of the microcapsules in simulated intestinal juice to be higher than 80%; (3) co-fermenting the microcapsules, clostridium butyricum and pediococcus acidilactici, and adsorbing fermentation liquor on the porous starch; (4) performing dry mixing on the functional compound, the fermentation compound and the base material, and performing low-temperature puffing; and (5) sequentially spraying a vitamin D3 grease layer, a pectin-whey protein protective layer and a solution containing TGF-beta2 on the surfaces of the particles. Through cooperation of multiple processes, the immune function and intestinal health of pets are remarkably improved, and the product is good in stability and palatability.