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399 results about "Embedding rate" patented technology

Method for preparing mono-disperse microemulsion, liposome and microsphere based on microfluidic technology

The invention discloses a method for preparing mono-disperse microemulsion, liposome and microspheres based on a microfluidic technology. The method comprises the following steps: taking aqueous solution (or oily solution) of a hydrophilic medicine (or a lipid-soluble medicine) as a disperse phase; taking an oil phase (or an aqueous phase) as a continuous phase; and respectively conveying the disperse phase and the continuous phase into corresponding micro-channels of a microfluidic chip device, shearing the phases into mono-disperse liquid drops of the encapsulated medicine, then curing the liquid drops by a certain curing method, and finally obtaining the medicine-carrying liposome, microspheres or the biodegradable microspheres with uniform size and dispersion stability. Under an optimum condition, the diameter distribution coefficients of the microemulsion and the microspheres can be less than 5%, and the diameter is 10-500microns. By utilizing the method, the problems such as uneven size, low embedding rate, poor dispersibility, poor targeting property, low bioavailability, low bioactivity of enzyme and cells, immune suppression and the like of the medicine-carrying microemulsion, the liposome and the microspheres prepared by the traditional ultrasonic method, agitation emulsification method and film hydration-dispersion method are solved.
Owner:TSINGHUA UNIV

Flaxseed oil microcapsule and production method thereof

The invention discloses a flaxseed oil microcapsule and a production method thereof. The core material of the flaxseed oil microcapsule is flaxseed oil, and the wall material is made of modified starch, maltodextrin and sodium caseinate. The production method comprises steps of adding the modified starch, the maltodextrin and the sodium caseinate to hot water with high-speed stirring until the the modified starch, the maltodextrin and the sodium caseinate are dissolved completely and forming a water phase; weighing and taking the flaxseed oil, adding vitamin E, rosemary and tea polyphenol step by step, stirring the mixture until the mixture is dissolved completely and forming an oil phase; conducting high-speed cutting for the obtained water phase by using a cutting machine, adding the obtained oil phase slowly and obtaining an emulsion; homogenizing the emulsion by using a high-pressure homogenizer; sterilizing the emulsion which is homogenized by using an ultra high-temperature sterilizing machine; and spraying and drying the sterilized and obtaining the flaxseed oil microcapsule. The embedding rate of the flaxseed oil microcapsule is more than 90%, the capacity of the flaxseed oil can reach 45%, the process is simple, the taste is special, the scent is obvious and the shelf life is long.
Owner:CHINA NAT RES INST OF FOOD & FERMENTATION IND CO LTD +3

Linseed oil microcapsule powder and preparation process thereof

The invention relates to linseed oil microcapsule powder and a preparation process thereof. The microcapsule powder is prepared from the following components in parts by weight: 38-45 parts of linseed oil, 0.002-0.02 part of an antioxidant, 48-54 parts of a filling agent, 6-8 parts of an emulsifier, 0-0.1 part of a stabilizer and 65-80 parts of water. The preparation process comprises the following steps: preparing an aqueous phase, preparing an oil phase, performing pre-emulsification, homogenizing and granulating. According to the final product obtained in the technical scheme of the invention, the surface is spherical under an environment scanning electron microscope, the particle size ranges from 35 microns to 100 microns, and the obtained product is a quick-dissolving product and is high in liquidity, high in re-watering stability, high in microcapsule oil embedding rate, good in embedding performance, good in taste and high in absorption rate; and moreover, the preparation process is simple, large-scale production is conveniently realized, contact between the linseed oil and air is effectively isolated by virtue of the microcapsule embedding technology, the biological activity of alpha-linolenic acid in the linseed oil is protected, waste residues and wastewater are not produced in the production process, and the product is green and environment-friendly.
Owner:王维义

Micro-capsulated suspended microbial seed coating agent and preparation method thereof

InactiveCN104430307AReduce adverse effectsGuaranteed effective bacteria contentBiocidePlant growth regulatorsSurvivabilityPseudomonas
The invention relates to a micro-capsulated suspended microbial seed coating agent and a preparation method thereof. The micro-capsulated suspended microbial seed coating agent comprises a functional bacteria microcapsule and auxiliaries, wherein the functional bacteria microcapsule is prepared from wall materials such as sodium alginate and gelatin by virtue of an endogenous emulsion process, the grain size of the microcapsule is 20-60 mu m, the content of functional bacteria is not lower than 10<9>cfu/g, and the embedding rate is over 80%. Functional microbes are selected from two or more of pseudomonas, bacillus subtilis, bacillus amyloliquefaciens, enterobacter cloacae, raoultella planticola and bacillus atrophaeus. The auxiliaries comprise one or more of a film-forming agent, a dispersant, a tackifier, an anti-freezing agent and a coloring agent. The prepared functional bacteria microcapsule is uniformly mixed with the auxiliaries to obtain a finished product. The product has the advantages of good film-forming performances, thallus persistence, high survivability, good slow-controlled release, strong application stability, environment friendliness, convenience in use, and the like, can be used for promoting seed germination and seedling growth of cottons, soya beans, wheat and potatoes, and the like, controlling the diseases at the seedling stage, improving stress resistance, and the like.
Owner:SHIHEZI UNIVERSITY +1

Spray freeze-drying preparation technology for polyunsaturated fatty acid oil microcapsule

The invention relates to a spray freeze-drying preparation technology for a polyunsaturated fatty acid oil microcapsule, which comprises the following technological steps: mixing oil containing polyunsaturated fatty acid with emulsifier and water to obtain mixture; homogenizing the mixture to obtain emulsion; atomizing the emulsion into liquid drops which are sprayed into a spray drying device with temperature of negative 60 DEG C to negative 10 DEG C, wherein powder embedding materials are contained at the bottom part of the spray drying device, and blasting low-temperature gas to fully mix the materials in the spray drying device and to keep the temperature in the spray drying device to be the set temperature; and further drying and screening to obtain polyunsaturated fatty acid oil microcapsule products. The invention has the advantages that the drying temperature of the preparation technology is low, the speed is fast and the nutritional ingredients are not apt to be damaged; the technology is simple and convenient and the automatic mass production can be realized; and the oil embedding rate of the obtained independent polyunsaturated fatty acid oil microcapsule particles is high, the embedding performance is good, the product shelf life is long and the stability is good.
Owner:CABIO BIOTECH WUHAN CO LTD

Anti-adhesion fiber membrane with hemostasis and antibiosis functions and preparation method thereof

InactiveCN102397580AIncrease embedding volumeHigh embedding rateAbsorbent padsBandagesFiberSurgical operation
The invention discloses an anti-adhesion fiber membrane with hemostasis and antibiosis functions and a preparation method thereof. The preparation method comprises the following steps of: dissolving medicinal molecules into an organic or inorganic solvent to prepare a medicinal molecular solution; dissolving different high molecular materials into medicinal solutions of a hemostasis agent and an antibiosis agent respectively to prepare a high molecular solution; and performing electrostatic spinning on a mixed solution of organic high molecules and the hemostasis agent and a mixed solution of high molecules and the antibiosis agent to obtain a compound fiber material. In the invention, nanofiber is produced by using an electrostatic spinning technology; an organic high molecular solution and the medicinal molecules are mixed for electrostatic spinning to obtain the compound fiber material; by adjusting the high molecular material, the embedding amount and embedding rate of medicaments are increased, a fiber material which can keep the medicinal bioactivity and is used for controlling the release of different medicaments at different stages is prepared, and dual effects of preventing postoperative adhesion and postoperative infection can be achieved; and moreover, the entire preparation process is simple, has low cost, and has wide application prospect in the field of surgical operation.
Owner:WUXI ZHONGKE GUANGYUAN BIOMATERIALS

Reversible information hiding method based on blocked self-adaptive histogram translation

The invention relates to the field of multimedia information security, in particular relates to a reversible information hiding method based on blocked self-adaptive histogram translation. The method comprises the following steps: (1) blocking a carrier image, and computing a peak value of each sub-block histogram; (2) self-adaptively selecting a sub-block for embedding information according to embedding capacity of each sub-block; (3) adopting a method for self-adaptively selecting histogram translation direction while embedding the information. The invention is a novel histogram translation method which is capable of effectively embedding the information and losslessly extracting the embedded information and recovering an original image; through the adoption of the blocked method, the embedded information is safer and the integral embedding rate is improved, the self-adaptive selected histogram translation direction can effectively improve the peak signal to noise ratio of the image to further improve the image quality, thereby providing help for the medical treatment, military and the like applications. Through the adoption of the method, the higher the precision of the image is, the better the reversible information hiding effect is.
Owner:SUN YAT SEN UNIV

Biodegradable microorganism sustained-release agent as well as preparation method and application thereof

The invention relates to a biodegradable microorganism sustained-release agent. The biodegradable microorganism sustained-release agent is prepared from microorganism bacterium powder, a carbon-source sustained-release body and a hydrogel bacterium agent carrier, wherein the microorganism bacterium powder and the carbon-source sustained-release body are suspended in the hydrogel bacterium agent carrier; the mass ratio of the carbon-source sustained-release body to the hydrogel bacterium agent carrier is 1 to (1 to 10000); the invention further relates to a preparation method and application of the microorganism sustained-release agent. The microorganism sustained-release agent provided by the invention has a remarkable sustained-release effect, the embedding rate of the microorganism bacterium powder is high and the sustained-release effect of the microorganism bacterium powder is remarkable; furthermore, the preparation method is simple and secondary pollution is effectively avoided; controllable release of a carbon source can be realized; the biodegradable microorganism sustained-release agent is applied to sewage management and waste of the carbon source, caused by flowing of a water body, can be effectively avoided through sustained-release of the carbon source, so that the utilization efficiency of microorganisms on the carbon source is improved and the nitrogen removal efficiency is improved; the ammonia-nitrogen reducing rate can reach 80 percent or more and the reducing rate of total nitrogen can reach 20 percent; a relatively good quality effect is realized.
Owner:浙江天韵生态环境工程有限公司 +1

Abscisic acid-embedded chitosan nanoparticles and preparation method thereof

The invention discloses abscisic acid-embedded chitosan nanoparticles and a preparation method thereof. The abscisic acid-embedded chitosan nanoparticles are nanoparticles formed by wrapping aqueous solution of abscisic acid by an embedding material which is formed by dilute solution of acetic acid of chitosan and a crosslinking agent. The preparation method comprises the following steps of: adding the chitosan into the dilute solution of acetic acid to be dissolved, and then adding solution of sodium hydroxide to adjust the pH value to obtain dilute solution of acetic acid of the chitosan; preparing abscisic acid into aqueous solution; preparing the crosslinking agent into aqueous solution; adding the solution of dilute acetic acid of the chitosan into the aqueous solution of abscisic acid, and then adding the aqueous solution of crosslinking agent drop by drop; and fully mixing uniformly to obtain the abscisic acid-embedded chitosan nanoparticles. The method is simple and easy, and has high embedding rate; the obtained embedding nanoparticles have no adhesion, good glomeration and round surface; after the embedding, the abscisic acid can be protected from external interference, and the stability of the abscisic acid can be improved; the abscisic acid is steadily and slowly released, which prolongs action time and strengthens induced resistance effect; and the chitosan serving as a wall material has disease-resistant and induced resistance effects.
Owner:GUIZHOU TOBACCO SCI INST
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