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Hydrated crystalline form of lazertinib methanesulfonate and methods of making and uses thereof

The application relates to the field of pharmaceutical chemistry. The application relates to a hydrate crystal form of lazertinib monomethanesulfonate and a preparation method and application thereof. The hydrate crystal form of lazertinib monomethanesulfonate provided by the application has at least one of the following advantages: good stability, good solubility, good dissolution, low hygroscopicity, uniform particle size distribution, good morphology, good fluidity, good crystallinity, stable storage, avoidance of degradation, impurity increase, appearance change and crystal transformation during development and storage, simple and reliable preparation method, and great development value.
Owner:SOLIPHARMA

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