This invention relates to the field of
biomedical technology and discloses an
exosome preparation for treating thin
endometrium and its preparation method. The preparation method includes the following steps: Step 1, culturing mesenchymal stem cells; Step 2, extracting exosomes; Step 3, preparing a collagen solution; Step 4, preparing
traditional Chinese medicine components; Step 5, stirring the collagen solution and sheep
placenta powder extract evenly at 4°C, then adding the
exosome solution and mixing, then adding soy isoflavone solution and excipients, and after sufficient reaction, obtaining an
exosome gel, which is then stored at 4°C. This invention utilizes the above-mentioned exosome preparation for treating thin
endometrium and its preparation method, using
collagen gel as a sustained-release matrix to provide three-dimensional structural support for the active substances, slowing down their degradation. Simultaneously, the growth factors in the sheep
placenta powder extract work synergistically with the exosomes to activate
angiogenesis, improve
blood supply, and promote endometrial regeneration.