11 results about "Monascus anka" patented technology

This invention application provides compositions containing red yeast rice pigment and their applications, compositions with α-glucosidase inhibitory activity and their applications, and further, their application in α-glucosidase inhibitors, belonging to the technical field of natural active compounds inhibiting α-glucosidase. The compositions of this invention comprise one or both of red yeast rice pigment and red yeast rice pigment: wherein the molar ratio of acarbose to red yeast rice pigment is 400:400-600:300; the molar ratio of acarbose to red yeast rice pigment is 400:200-600:150; and the molar ratio of red yeast rice pigment to red yeast rice pigment is 150:400-200:300. The compositions involved in this invention have a significant synergistic inhibitory effect on α-glucosidase, superior to using the above compounds alone, and can achieve reduced drug dosage and reduced drug side effects.

The utility model relates to oral liquid processing technical field especially relates to a kind of deployment device of red yeast oral liquid, it includes red yeast oral liquid deployment cylinder, and red yeast oral liquid deployment cylinder inside is provided with mixing mechanism, and red yeast oral liquid deployment cylinder side is provided with circulating mechanism;Mixing mechanism includes rotating lever, and rotating lever is rotatably installed at red yeast oral liquid deployment cylinder bottom, and several lower folding rods and upper folding rods are evenly installed on the lateral wall of rotating lever, and the lateral wall of lower folding rod and upper folding rod is fixedly connected with web plate, and the lateral wall of web plate is evenly provided with through-hole, and the inside of rotating lever is fixedly installed with electric telescopic rod, and the output end of electric telescopic rod is slidably passed to the upper side of rotating lever and the upper end of electric telescopic rod is fixedly installed with top disc piece.The utility model is provided with mixing mechanism, can strengthen stirring mixing action, and part of solution will pass through from the through-hole in web plate while stirring, realizes the convection effect of part of solution while stirring, and improves the mixing effect of solution.

This utility model relates to the technical field of red yeast rice extract processing equipment, and discloses a high-efficiency concentration and separation device for red yeast rice extract, including a processing mechanism with a support mechanism at the bottom; the processing mechanism includes a base plate, a mixing tank fixedly connected to the top left side of the base plate, a rotating rod rotatably connected inside the mixing tank, a spiral stirring blade fixedly connected to the surface of the rotating rod, a motor fixedly connected to the top of the rotating rod, a heater installed inside the mixing tank, and a feed pipe fixedly connected to the top of the mixing tank. This high-efficiency concentration and separation device for red yeast rice extract, driven by the motor, enables the spiral stirring blades to form a three-dimensional circulating stirring effect within the mixing tank. This stirring method can fully disperse the raw materials, allowing the extract to have comprehensive and multi-layered contact and reaction with the raw materials, greatly increasing the chances of dissolution and precipitation of the effective components, thereby significantly improving the extraction rate of the effective components.

This invention proposes an analytical method for evaluating the quality of red yeast rice based on HPLC fingerprinting and multi-component quantitative analysis, belonging to the field of quality control technology for red yeast rice and related products. The method includes: taking a red yeast rice sample, ultrasonically extracting it with 50% methanol, centrifuging, and filtering to prepare a test solution; performing detection using high-performance liquid chromatography; constructing a red yeast rice fingerprint chromatogram based on the detection results, and simultaneously determining the content of six active ingredients: ankaflavin, citrinin, lactone-type mevastatin, lactone-type lovastatin, acid mevastatin, and acid lovastatin; and combining chemical pattern recognition methods to perform discriminant analysis on red yeast rice samples from different sources to evaluate the quality of the red yeast rice. This invention achieves an organic combination of simultaneous quantitative analysis of multiple components in red yeast rice and overall quality evaluation based on fingerprint chromatograms. Methodological validation shows that this method has good precision, repeatability, and stability, and is accurate and reliable, suitable for the quality control of red yeast rice raw materials and health foods and pharmaceuticals containing red yeast rice.

The utility model relates to the technical field of monascus extract storage, and disclose a kind of anti-deposition stirring device for monascus extract storage, comprising: support plate, its top is equipped with accommodating groove, the accommodating groove is fixedly connected with the storage container for storing monascus extract in;Vertically arranged stirring shaft.The anti-deposition stirring device for monascus extract storage, driving motor drives stirring shaft rotation, so that three groups of stirring vane and the conical anti-deposition head of bottom rotate, and the rotational direction of adjacent two groups of stirring vane is opposite and is arranged to enhance fluid axial mixing ability, form up and down convection, break down sedimentation stratification, bottom sharp cone structure reduces sedimentation adhesion, spoiler further disturbs fluid boundary layer, spoiler is made of stainless steel sheet, with certain strength and corrosion resistance, while circulating pump extracts container bottom liquid by first circulating pipe, is transported to top by second circulating pipe, forms forced circulation flow, makes up partiality of mechanical stirring, realizes full container uniform mixing.

This invention provides a red yeast rice fermentation product for eliminating nodules. A group of important compositions for eliminating nodules were screened and obtained, including dihydroquercetin, Tian Shan snow lotus culture, chicken gizzard lining, dandelion, prunella vulgaris, platycodon grandiflorus, and black buckwheat. The culture medium was prepared using the traditional Chinese medicine composition, and red yeast rice was inoculated for fermentation. This process transformed the large active molecules in the traditional Chinese medicine composition that eliminate nodules into small active molecules such as aglycones, thereby enhancing the efficacy of eliminating nodules and significantly improving the therapeutic effect of the traditional Chinese medicine composition in eliminating nodules, thus meeting clinical needs.

This utility model discloses a material washing device for red yeast rice fermentation; belonging to the field of red yeast rice fermentation material washing, it includes a first washing component, a drive component at the front end of the first washing component, and a second washing component inside the first washing component; the drive component includes an equipment box, a motor inside the equipment box, a drive shaft fixedly connected to the drive end of the motor, the drive shaft being rotatably connected to the equipment box, and multiple connecting arms fixedly connected to the outer wall of the drive shaft. Automated reciprocating washing is achieved through motor drive, improving efficiency and reducing labor costs; the design of springs and movable rods inside the equipment box plays a buffering and reset role, ensuring stable operation and extending service life; the plug-in method of the washing bucket hook strip and movable strip facilitates installation and disassembly, and is conducive to maintenance; the water tank drain pipe facilitates wastewater discharge; the reciprocating motion ensures full contact between the material and water without damaging the outer surface of the material, ensuring the integrity of the material and improving the washing quality.

Provided are a monascus strain capable of producing monascin and / or ankaflavin and the use thereof. Particularly, provided are a new monascus strain assigned with the accession number CGMCC NO. 41335 and the use thereof in the production of high-content monascin and / or ankaflavin and related products thereof. The strain is Monascus purpureus ZYXQ-2206, can produce potent and non-toxic lipid-lowering ingredients monascin and / or ankaflavin with a high yield, and does not produce harmful and toxic ingredients lovastatin (LOV) and citrinin (CIT). Since excessive intake of LOV can cause serious side effects such as liver and kidney injury and rhabdomyolysis, and excessive intake of CIT can cause toxic responses such as renal tubular dilation and degeneration and necrosis of epithelial cells, the monascus products produced by using the strain can effectively avoid these safety risks, and have extremely high application prospects and market potentials. By screening and optimizing a fermentation process, the monascus strain having high productivity, no toxicity and high functionality is provided, which has significant application value in the fields of development of lipid-lowering functional foods and dietary supplements.

The present application relates to the technical field of pigment detection, and discloses a method for simultaneously detecting monascine MS and monascin AK, which comprises the steps of adding an extraction solvent to a test sample to perform extraction, obtaining a test sample solution, and performing HPLC detection. The HPLC detection conditions are as follows: using a cholesteryl group bonded silica gel filler as a filler, using acetonitrile as a mobile phase A, and using 0.05-0.2% (v / v) formic acid as a mobile phase B to perform gradient elution. In the method for simultaneously detecting monascine MS and monascin AK, the extraction efficiency of target components MS and AK in a sample is improved by optimizing an extraction process, HPLC detection effectively separates MS, AK and other interfering components in monascin, realizes accurate quantification of MS and AK, and the quantitative results are directly related to medicinal efficacy, thereby meeting compliance requirements of active ingredient labeling.

The application provides application of a monascus composition in preparation of a medicine for preventing and / or treating coronary microcirculation disorder, wherein the monascus composition comprises one or more of mulberry bark, mulberry branch and mulberry leaf, monascus and pueraria. When the monascus composition is applied in preparation of the medicine for preventing and / or treating coronary microcirculation disorder, the following effects can be achieved: 1) improving microvascular structure abnormality (increasing myocardial microvascular density MVD, reducing perivascular edema of microvessels, improving lumen stenosis phenomenon, and good endothelial cell condition); 2) improving microvascular obstruction (pathological results show that the content of microvessels is reduced); 3) improving abnormal microvascular vasomotor function (increasing NO); 4) improving blood lipid metabolism disorder; and 5) improving heart function (increasing left ventricular ejection fraction LVEF and left ventricular short axis shortening rate LVFS, increasing left ventricular internal pressure maximum rising rate LV+dp / dtmax and left ventricular internal pressure maximum falling rate LV‑dp / dtmax).