Patents
Literature
Patsnap Eureka AI that helps you search prior art, draft patents, and assess FTO risks, powered by patent and scientific literature data.

20 results about "Monascus anka" patented technology

Natto red yeast rice herb bean flour and preparation method thereof

PendingCN121534141AFungiBacteriaBiotechnologyMonascus anka
The invention relates to the technical field of microbial fermentation engineering, and particularly discloses natto red yeast rice herb bean flour and a preparation method thereof. The preparation method comprises the following steps: respectively activating specifically preserved bacillus natto and monascus to obtain secondary seed solutions; inoculating the two seed solutions into a solid-state fermentation culture medium for co-fermentation; and inactivating, drying and crushing the fermentation product to obtain a finished product. The solid-state fermentation culture medium is prepared by compounding a bean matrix (soybeans, black beans or chickpeas) and herb tea components (roses, lotus leaves, chrysanthemums, mulberry leaves, haws, cassia seeds and the like). Through the synergistic effect of the bacillus natto and the monascus, nattokinase and monacolin K are efficiently enriched in a single fermentation system at the same time, conversion of soy isoflavone to a high-bioavailability aglycone type is remarkably promoted, and the obtained product has multiple health-care functions of thrombolysis, lipid reduction, efficient absorption and the like.
Owner:JIANGNAN UNIV +1

Fungus preparation for improving fermentation performance of monascus purpureus and application of fungus preparation

The invention discloses a fungal preparation for improving the fermentation performance of monascus purpureus and application of the fungal preparation. The fungus preparation is prepared by compounding Aspergillus niger MQM20136, Monascus purpureus 40269 and Saccharomyces cerevisiae JH301 direct vat set fungicide, the Aspergillus niger MQM20136 is preserved in the China Center for Type Culture Collection in Wuhan, the preservation time is September 25, 2025, and the preservation number is CCTCC (China Center for Type Culture Collection) NO: M 20252120. According to the invention, a fungus preparation taking the aspergillus niger MQM20136 as a main body is constructed, a mutualism and synergistic interaction microbial system is formed in the fungus preparation, and when the fungus preparation is used for pure compound preparation of the monascus purpureus, the quality stability, the esterification capacity, the wine yield and other fermentation properties of the monascus purpureus can be improved.
Owner:INST OF AGRI ENG TECH FUJIAN ACAD OF AGRI SCI

Monascus yellow pigment composition and application thereof, composition with alpha-glucosidase inhibitory activity and application thereof

ActiveCN117442605BRed yeast riceAlglucerase
This invention application provides compositions containing red yeast rice pigment and their applications, compositions with α-glucosidase inhibitory activity and their applications, and further, their application in α-glucosidase inhibitors, belonging to the technical field of natural active compounds inhibiting α-glucosidase. The compositions of this invention comprise one or both of red yeast rice pigment and red yeast rice pigment: wherein the molar ratio of acarbose to red yeast rice pigment is 400:400-600:300; the molar ratio of acarbose to red yeast rice pigment is 400:200-600:150; and the molar ratio of red yeast rice pigment to red yeast rice pigment is 150:400-200:300. The compositions involved in this invention have a significant synergistic inhibitory effect on α-glucosidase, superior to using the above compounds alone, and can achieve reduced drug dosage and reduced drug side effects.
Owner:TIANJIN UNIV OF SCI & TECH +1

Fingerprint detection method of red yeast rice

The invention discloses a red yeast rice fingerprint spectrum detection method. The fingerprint detection method is developed for the monacolin compound in the monascus, whether the to-be-detected sample contains the monascus meeting the quality requirement or not can be directly judged by comparing the similarity of the to-be-detected sample and the contrast fingerprint, the detection efficiency is improved, and the detection cost is reduced.
Owner:SHANGHAI INST FOR FOOD & DRUG CONTROL

Quality control method of fried red yeast rice

The invention relates to the field of food preparation, in particular to a quality control method of fried monascus, which comprises the following steps: estimating the growth situation of monascus according to character data of monascus in a culture medium so as to adjust activation culture conditions; obtaining biological characteristics of monascus in the culture medium, and carrying out subregion calibration on the culture medium, so as to extract monascus and prepare a monascus strain solution; curing the pretreated rice raw material to obtain an inactivated raw material, and adjusting the inoculation operation of the inactivated raw material according to the internal structure of the inactivated raw material; predicting the fermentation trend according to the fermentation actual condition data of the inactivated raw material so as to adjust the fermentation condition, and screening the fermentation product to obtain a monascus product; and performing adjustable stir-frying operation on the red yeast rice product to obtain the processed red yeast rice. According to the method, the whole process from monascus culture to monascus extraction and strain liquid preparation is optimized, the purity of the monascus strain liquid is improved, the monascus production period is shortened, and a raw material with reliable and stable quality is provided for improving the monascus production quality.
Owner:TONG JUN GU SHENG WU YI YAO KE JI (ZHE JIANG) YOU XIAN GONG SI

A device for preparing monascus oral liquid

ActiveCN224541492UMonascus ankaMechanical engineering
The utility model relates to oral liquid processing technical field especially relates to a kind of deployment device of red yeast oral liquid, it includes red yeast oral liquid deployment cylinder, and red yeast oral liquid deployment cylinder inside is provided with mixing mechanism, and red yeast oral liquid deployment cylinder side is provided with circulating mechanism;Mixing mechanism includes rotating lever, and rotating lever is rotatably installed at red yeast oral liquid deployment cylinder bottom, and several lower folding rods and upper folding rods are evenly installed on the lateral wall of rotating lever, and the lateral wall of lower folding rod and upper folding rod is fixedly connected with web plate, and the lateral wall of web plate is evenly provided with through-hole, and the inside of rotating lever is fixedly installed with electric telescopic rod, and the output end of electric telescopic rod is slidably passed to the upper side of rotating lever and the upper end of electric telescopic rod is fixedly installed with top disc piece.The utility model is provided with mixing mechanism, can strengthen stirring mixing action, and part of solution will pass through from the through-hole in web plate while stirring, realizes the convection effect of part of solution while stirring, and improves the mixing effect of solution.
Owner:HUBEI COLLEGE OF TRADITIONAL CHINESE MEDICINE +1

Preparation method of monascus summer tea

PendingCN121512065APre-extraction tea treatmentMetaboliteMonascus anka
The invention is applicable to the technical field of functional tea drink processing, and provides a preparation method of monascus summer tea, which comprises the following steps: carrying out synergistic pretreatment of pulsed electric field and compound enzymolysis on summer tea; inoculating a compound microbial agent composed of monascus, aspergillus niger and lactobacillus plantarum for fermentation; the synthesis of different metabolites is accurately regulated and controlled by adopting a four-stage dynamic temperature change process; a targeted activator system composed of L-arabinose, vitamin C and betaine is added in a key metabolism window stage; an in-situ enzymatic glycosylation system composed of cyclodextrin glycosyl transferase and sucrose synthase is introduced, and monacolin K and tea polyphenol are modified. According to the invention, pH / temperature dual-response targeted activation, fructo-oligosaccharide synergistic in-situ glycosylation and stable network construction are fused with multi-strain synergistic fermentation and dynamic metabolism regulation for the first time, so that the yield, bioavailability, flavor quality and storage stability of monacolin K in a final product are remarkably improved.
Owner:HANGZHOU TWIN-HORSE BIOENGINEERING CO LTD

A high-efficiency concentrating and separating device for monascus extract

This utility model relates to the technical field of red yeast rice extract processing equipment, and discloses a high-efficiency concentration and separation device for red yeast rice extract, including a processing mechanism with a support mechanism at the bottom; the processing mechanism includes a base plate, a mixing tank fixedly connected to the top left side of the base plate, a rotating rod rotatably connected inside the mixing tank, a spiral stirring blade fixedly connected to the surface of the rotating rod, a motor fixedly connected to the top of the rotating rod, a heater installed inside the mixing tank, and a feed pipe fixedly connected to the top of the mixing tank. This high-efficiency concentration and separation device for red yeast rice extract, driven by the motor, enables the spiral stirring blades to form a three-dimensional circulating stirring effect within the mixing tank. This stirring method can fully disperse the raw materials, allowing the extract to have comprehensive and multi-layered contact and reaction with the raw materials, greatly increasing the chances of dissolution and precipitation of the effective components, thereby significantly improving the extraction rate of the effective components.
Owner:HANGZHOU TWIN-HORSE BIOENGINEERING CO LTD

Application of polysaccharide monascus extract in preparation of nerve cell antioxidant drugs

The invention relates to the technical field of biology, and discloses application of a polysaccharide monascus extract in preparation of a nerve cell antioxidant drug, and the nerve cell antioxidant drug is used for reducing cell death caused by oxidation and reducing cell active oxygen. The polysaccharide monascus extract has a protection effect on nerve cells in an oxidative stress state. The polysaccharide monascus extract provided by the invention can reduce cell viability reduction, cell death and the level of cell reactive oxygen species (ROS) caused by oxidative stress.
Owner:GUANGDONG ZHENHONG BIOTECHNOLOGY CO LTD

An analysis method for evaluating the quality of monascus based on HPLC fingerprint and multi-component quantification

PendingCN122259757AComponent separationBiotechnologyHplc fingerprint
This invention proposes an analytical method for evaluating the quality of red yeast rice based on HPLC fingerprinting and multi-component quantitative analysis, belonging to the field of quality control technology for red yeast rice and related products. The method includes: taking a red yeast rice sample, ultrasonically extracting it with 50% methanol, centrifuging, and filtering to prepare a test solution; performing detection using high-performance liquid chromatography; constructing a red yeast rice fingerprint chromatogram based on the detection results, and simultaneously determining the content of six active ingredients: ankaflavin, citrinin, lactone-type mevastatin, lactone-type lovastatin, acid mevastatin, and acid lovastatin; and combining chemical pattern recognition methods to perform discriminant analysis on red yeast rice samples from different sources to evaluate the quality of the red yeast rice. This invention achieves an organic combination of simultaneous quantitative analysis of multiple components in red yeast rice and overall quality evaluation based on fingerprint chromatograms. Methodological validation shows that this method has good precision, repeatability, and stability, and is accurate and reliable, suitable for the quality control of red yeast rice raw materials and health foods and pharmaceuticals containing red yeast rice.
Owner:HUNAN UNIV OF CHINESE MEDICINE

Anti-precipitation stirring device for monascus extract storage

The utility model relates to the technical field of monascus extract storage, and disclose a kind of anti-deposition stirring device for monascus extract storage, comprising: support plate, its top is equipped with accommodating groove, the accommodating groove is fixedly connected with the storage container for storing monascus extract in;Vertically arranged stirring shaft.The anti-deposition stirring device for monascus extract storage, driving motor drives stirring shaft rotation, so that three groups of stirring vane and the conical anti-deposition head of bottom rotate, and the rotational direction of adjacent two groups of stirring vane is opposite and is arranged to enhance fluid axial mixing ability, form up and down convection, break down sedimentation stratification, bottom sharp cone structure reduces sedimentation adhesion, spoiler further disturbs fluid boundary layer, spoiler is made of stainless steel sheet, with certain strength and corrosion resistance, while circulating pump extracts container bottom liquid by first circulating pipe, is transported to top by second circulating pipe, forms forced circulation flow, makes up partiality of mechanical stirring, realizes full container uniform mixing.
Owner:HANGZHOU TWIN-HORSE BIOENGINEERING CO LTD

Monascus polysaccharide-based fully biodegradable packaging material and preparation method thereof

PendingCN121554830AFlexible coversWrappersPolymer scienceMonascus anka
The invention belongs to the technical field of degradable packaging materials, and relates to a monascus polysaccharide-based fully biodegradable packaging material, which is prepared from the following raw materials in parts by weight: 60 to 70 parts of modified monascus polysaccharide; 10 to 20 parts of a composite modifier; 5-10 parts of a plasticizer; 3-5 parts of a filling agent; 0.3 to 0.5 part of vitamin E; the mechanical property, the water resistance and the forming stability of the monascus polysaccharide-based material are improved through a composite modification system, and finally the degradable packaging material which is low in cost, high in degradation efficiency and excellent in use performance is prepared.
Owner:HUBEI COLLEGE OF TRADITIONAL CHINESE MEDICINE

Packaging box (monascus tablet)

ActiveCN309954487SRed yeast riceMonascus anka
1. Name of the product in this design: Packaging Box (Red Yeast Rice Tablet). 2. Purpose of this design: For use in packaging boxes. 3. The key design features of this product are the combination of shape and pattern. 4. The image or photograph that best illustrates the design's key features: the front view.
Owner:XIAMEN SHIXIN PHARMACEUTICAL CO LTD

Monascus fermentation product for reducing nodules

This invention provides a red yeast rice fermentation product for eliminating nodules. A group of important compositions for eliminating nodules were screened and obtained, including dihydroquercetin, Tian Shan snow lotus culture, chicken gizzard lining, dandelion, prunella vulgaris, platycodon grandiflorus, and black buckwheat. The culture medium was prepared using the traditional Chinese medicine composition, and red yeast rice was inoculated for fermentation. This process transformed the large active molecules in the traditional Chinese medicine composition that eliminate nodules into small active molecules such as aglycones, thereby enhancing the efficacy of eliminating nodules and significantly improving the therapeutic effect of the traditional Chinese medicine composition in eliminating nodules, thus meeting clinical needs.
Owner:QIANJIEXIAO (ZHEJIANG) BIOTECHNOLOGY CO LTD

A material washing device for monascus fermentation

This utility model discloses a material washing device for red yeast rice fermentation; belonging to the field of red yeast rice fermentation material washing, it includes a first washing component, a drive component at the front end of the first washing component, and a second washing component inside the first washing component; the drive component includes an equipment box, a motor inside the equipment box, a drive shaft fixedly connected to the drive end of the motor, the drive shaft being rotatably connected to the equipment box, and multiple connecting arms fixedly connected to the outer wall of the drive shaft. Automated reciprocating washing is achieved through motor drive, improving efficiency and reducing labor costs; the design of springs and movable rods inside the equipment box plays a buffering and reset role, ensuring stable operation and extending service life; the plug-in method of the washing bucket hook strip and movable strip facilitates installation and disassembly, and is conducive to maintenance; the water tank drain pipe facilitates wastewater discharge; the reciprocating motion ensures full contact between the material and water without damaging the outer surface of the material, ensuring the integrity of the material and improving the washing quality.
Owner:WUHAN JIACHENG BIOTECH

Starch-based monascus pigment microcapsule as well as preparation method and application thereof

The invention provides a starch-based monascus pigment microcapsule as well as a preparation method and application thereof, and belongs to the technical field of food. The starch-based monascus pigment microcapsule disclosed by the invention forms a stable embedding structure through hydrogen bonds, so that the thermal decomposition temperature is increased from 260 DEG C to over 296 DEG C, and after microencapsulation, the light stability and storage stability of the monascus pigment are remarkably enhanced; the raw materials adopted by the starch-based monascus pigment microcapsule are all natural sources and accord with the national food safety standard, the preparation process is a pure physical process, and no chemical reaction is introduced; the coloring agent adding mode is compatible with a traditional sausage production process, the preparation and application process is simple and controllable, the equipment requirement is low, and industrial popularization is easy. The starch-based monascus pigment microcapsule is applied to preparation of sausages, the redness value and sensory score of the sausages are remarkably improved, the peroxide value of the sausages is remarkably reduced, and the problem that the existing sausages fade and become yellow due to oxidative degradation of monascus pigments in the storage process is solved.
Owner:SOUTH CHINA AGRICULTURAL UNIVERSITY

Monascus strain capable of producing monascin and / or ankaflavin with high yield and use thereof

PCT designated stageWO2026145497A1BiotechnologyLiver and kidney
Provided are a monascus strain capable of producing monascin and / or ankaflavin and the use thereof. Particularly, provided are a new monascus strain assigned with the accession number CGMCC NO. 41335 and the use thereof in the production of high-content monascin and / or ankaflavin and related products thereof. The strain is Monascus purpureus ZYXQ-2206, can produce potent and non-toxic lipid-lowering ingredients monascin and / or ankaflavin with a high yield, and does not produce harmful and toxic ingredients lovastatin (LOV) and citrinin (CIT). Since excessive intake of LOV can cause serious side effects such as liver and kidney injury and rhabdomyolysis, and excessive intake of CIT can cause toxic responses such as renal tubular dilation and degeneration and necrosis of epithelial cells, the monascus products produced by using the strain can effectively avoid these safety risks, and have extremely high application prospects and market potentials. By screening and optimizing a fermentation process, the monascus strain having high productivity, no toxicity and high functionality is provided, which has significant application value in the fields of development of lipid-lowering functional foods and dietary supplements.
Owner:BEIJING SCICURECANCER TECH CO LTD

A method for simultaneously detecting monascus yellow MS and AK

The present application relates to the technical field of pigment detection, and discloses a method for simultaneously detecting monascine MS and monascin AK, which comprises the steps of adding an extraction solvent to a test sample to perform extraction, obtaining a test sample solution, and performing HPLC detection. The HPLC detection conditions are as follows: using a cholesteryl group bonded silica gel filler as a filler, using acetonitrile as a mobile phase A, and using 0.05-0.2% (v / v) formic acid as a mobile phase B to perform gradient elution. In the method for simultaneously detecting monascine MS and monascin AK, the extraction efficiency of target components MS and AK in a sample is improved by optimizing an extraction process, HPLC detection effectively separates MS, AK and other interfering components in monascin, realizes accurate quantification of MS and AK, and the quantitative results are directly related to medicinal efficacy, thereby meeting compliance requirements of active ingredient labeling.
Owner:CHINA RESOURCES SANJIU MEDICAL & PHARMA CO LTD

Monascus culture function cabinet

The utility model relates to the technical field of monascus, in particular to a monascus culture function cabinet which comprises a cabinet body, a plurality of placing trays are installed in the cabinet body at equal intervals through sliding structures, and the placing trays are used for bearing mixtures of monascus strains and rice. The pneumatic jacking and humidifying assembly is arranged, so that a mixture of rice and monascus strains can be subjected to vibration loosening, ventilation cooling, humidification and oxygenation at the same time, and culture of the monascus and fermentation of the monascus on the rice can be accelerated; vibration, air adding, humidifying and oxygen adding are all carried out from the bottom of the mixture, so that air containing oxygen and moisture penetrates through the mixture through gaps generated by vibration and makes contact with the mixture more fully and evenly, cooling, humidifying and oxygen adding are more comprehensive and thorough, and compared with direct water spraying humidifying through a spray head, water consumption is lower, and energy consumption is lower. The lifting column is driven by air to lift, and the mixture can be vibrated without a polarization motor.
Owner:HANGZHOU DERUNQUAN BIOPHARMACEUTICAL CO LTD

Use of a monascus composition in the preparation of a medicament for treating coronary microcirculation disorder

ActiveCN120771236BPerivascular edemaMonascus anka
The application provides application of a monascus composition in preparation of a medicine for preventing and / or treating coronary microcirculation disorder, wherein the monascus composition comprises one or more of mulberry bark, mulberry branch and mulberry leaf, monascus and pueraria. When the monascus composition is applied in preparation of the medicine for preventing and / or treating coronary microcirculation disorder, the following effects can be achieved: 1) improving microvascular structure abnormality (increasing myocardial microvascular density MVD, reducing perivascular edema of microvessels, improving lumen stenosis phenomenon, and good endothelial cell condition); 2) improving microvascular obstruction (pathological results show that the content of microvessels is reduced); 3) improving abnormal microvascular vasomotor function (increasing NO); 4) improving blood lipid metabolism disorder; and 5) improving heart function (increasing left ventricular ejection fraction LVEF and left ventricular short axis shortening rate LVFS, increasing left ventricular internal pressure maximum rising rate LV+dp / dtmax and left ventricular internal pressure maximum falling rate LV‑dp / dtmax).
Owner:BEIJING WBL PEKING UNIV BIOTECH