1462 results about "Flavonoid" patented technology

The invention discloses a calendula double-bacterium fermentation product as well as a preparation method and application thereof, and relates to the technical field of plant fermentation. The preparation method of the calendula double-bacterium fermentation product disclosed by the invention comprises the following steps: carrying out primary fermentation by using lactobacillus plantarum, then carrying out secondary fermentation by using saccharomyces cerevisiae, and carrying out sterilization and filtration treatment on the calendula fermentation liquid subjected to secondary fermentation, so as to obtain the calendula fermentation liquid. The calendula fermentation liquor is subjected to combined fermentation through lactobacillus plantarum and saccharomyces cerevisiae, and the content of polyphenol and flavone in the calendula double-bacterium fermentation product is remarkably increased. Meanwhile, the calendula double-bacterium fermentation product has the effects of preserving moisture, resisting oxidation, relieving and controlling oil, and has a wide application prospect in the field of cosmetics.

The invention belongs to the technical field of food microorganisms, and relates to lactobacillus plantarum and application thereof in preparation of products for relieving insomnia. The preservation number of the lactobacillus plantarum is GDMCC No: 65061. The lactobacillus plantarum can be applied to efficient fermentation of spina date seed juice, the content of GABA, polypeptide, total phenols and total flavonoids in the spina date seed juice is increased, and the content of spinosin, 6 ''-feruloyl spinosin, jujuboside A, jujuboside B and betulinic acid is increased; the reduction of whole brain coefficient and the increase of liver coefficient caused by long-term insomnia are relieved, the bad condition caused by long-term insomnia in a hippocampus DG region in the brain of the mouse is improved, the sleep time of the mouse is prolonged, and the insomnia symptom of the mouse is relieved; the content of inhibitory neurotransmitters 5-hydroxytryptamine, melatonin and gamma-aminobutyric acid in the hypothalamus of the mouse is increased, the content of excitatory neurotransmitter glutamic acid is reduced, and the reduction of organism immunity and oxidative stress of brain tissues caused by insomnia are relieved.

The invention provides a preparation method of cereal fermentation broth postbiotics and application of the cereal fermentation broth postbiotics in improvement of systemic chronic inflammation and reduction of cholesterol and low-density lipoprotein, and belongs to the technical field of fermentation engineering. The invention provides a preparation method of cereal fermentation broth metabiotics, which is characterized in that mixed cereals are used as raw materials, anaerobic fermentation is carried out by using compound enzymes and various bacteria, and polysaccharides and proteins in the cereal raw materials can be quickly converted into functional small molecular substances, such as polypeptides, total phenols and total flavonoids. The cereal fermentation broth metagen can inhibit secretion of a macrophage proinflammatory medium, inhibit generation of inflammatory factors of liver, heart and intestinal tissues, and improve activation of adipose tissue macrophages related to body inflammation. After the cereal fermentation liquor is subjected to post-biogen treatment, glucose and lipid metabolism disorder can be effectively improved, liver function damage can be relieved, and the intestinal barrier function can be effectively improved.

The invention discloses an ulva lactuca composite wall-breaking enzymolysis fermentation product as well as a preparation method and application thereof, and relates to the field of cosmetics. The preparation method comprises the following steps: soaking ulva powder, and performing physical cell wall breaking treatment; mixed enzymes are added for an enzymolysis reaction, wherein the mixed enzymes comprise lipase, cell wall breaking enzyme, enzyme and protease; adding the enzymolysis product into a culture medium, and inoculating bacterial liquid for fermentation culture to obtain fermentation liquid. According to the application, active ingredients such as macromolecular polysaccharide and protein in the ulva lactuca are extracted and decomposed by adopting physical cell wall breaking, composite enzymolysis and bifidus yeast fermentation technologies, and the prepared fermentation product is rich in various composite micromolecular active ingredients such as oligosaccharide, polypeptide, amino acid, polyphenols and flavonoids, has high free radical scavenging capacity, and can be used for preparing the ulva lactuca beverage. The anti-wrinkle and anti-oxidation composition has good anti-wrinkle and anti-oxidation effects, is beneficial to skin absorption when being applied to cosmetics and has high absorption efficiency, and the prepared cosmetics have excellent anti-wrinkle, anti-oxidation, soothing and repairing effects.

The invention provides application of an enhanced and optimized mesenchymal stem cell exosome in knee osteoarthritis and muscle cartilage injury, and belongs to the technical field of biological medicine. The treatment activity of the umbilical cord mesenchymal stem cell exosome is remarkably improved by combining a composite pretreatment technology with a 3D culture system. Through the synergistic effect of the total flavonoids of rhizoma drynariae and tanshinone IIA, the pathological process of knee osteoarthritis can be regulated and controlled in multiple dimensions, including inflammatory reaction inhibition, cartilage repair promotion and joint function improvement, and the functional limitation of single-component pretreatment is broken through. The invention provides a safe and efficient novel treatment technical strategy for relieving knee osteoarthritis and muscle cartilage injury, and has a wide clinical application prospect.

The invention relates to application of turmeric rhizome extract emulsifiable concentrate in preventing and treating corn leaf spot and tomato gray mold. Compared with the prior art, the turmeric rhizome extract missible oil disclosed by the invention contains an effective substance aromatic turmerone, and the aromatic turmerone can reduce the spore germination rate and sporulation quantity of pathogenic bacteria, increase the permeability of hypha cell membranes and cause overflow of contents, so that normal growth of hyphae is inhibited, and an antibacterial effect is achieved. Aromatic turmerone acts on plants, so that plant cells generate more polyphenol and flavonoid substances, and the immunity of the plants is improved. Pharmacodynamic test results in fields in two fields show that the 6.5% turmeric rhizome extract emulsifiable concentrate can be used for stably and effectively preventing and treating corn northern leaf blight and tomato gray mold after being diluted by 150-300 times, and also has a yield increasing effect.

The invention relates to the technical field of food, and particularly discloses a compound prebiotics embedded probiotic microcapsule and a preparation method and application thereof.The green tea leaves serve as main raw materials, water extraction is conducted on the green tea leaves, meanwhile, ultrasonic-assisted treatment is adopted, active ingredients in the green tea leaves can be more effectively released, the extraction time is shortened, and the content of probiotics in the green tea leaves is increased; the extraction rate of active ingredients in the green tea leaves is improved; then, lactobacillus acidophilus is adopted to ferment the extract liquid, so that the green tea fermentation liquid contains more antioxidant active ingredients, combined polyphenol in the extract liquid can release micromolecular polyphenol in the fermentation process, the content of substances such as flavone and polyphenol in the green tea fermentation liquid is increased, and the antioxidant activity is further improved; and then the modified dietary fiber is used as a main wall material of the microcapsule to embed the green tea fermentation liquor and the probiotics, so that the stability of active substances and the probiotics in the green tea fermentation liquor is improved, and the green tea fermentation liquor can play a role in protection and slow release in the simulated digestion process.

The invention relates to a whitening and freckle-removing composition containing a composite plant extract and a preparation method of the whitening and freckle-removing composition, and belongs to the technical field of cosmetics. The composition disclosed by the invention is prepared from the following raw materials in parts by weight: 5 to 8 parts of pineapple leaf nano cellulose, 10 to 16 parts of modified starch, 10 to 15 parts of longan seed extract, 6 to 10 parts of mulberry bark extract, 5 to 8 parts of nicotinamide and 8 to 10 parts of hyaluronic acid. The pineapple leaf nanocellulose contains flavonoid and phenolic compounds with double-bond, conjugated double-bond and triple-bond structures, and modified starch is used as a filler to form a film on the surface of skin, so that an anti-ultraviolet protection wall is formed; the betaine-malate ionic liquid is added into the longan seeds, so that extraction of polyphenol in the longan seeds is improved, the longan seeds have acid-base buffering capacity, an auxiliary does not need to be added to adjust the pH value, the components of the prepared composition interact, and the whitening and freckle removing effects are achieved from multiple aspects of ultraviolet resistance, oxidation resistance, inflammation resistance and skin metabolism improvement.

The invention discloses a fructus psoraleae total flavone extract as well as a preparation method and application thereof in promoting hair growth. According to the preparation method of the fructus psoraleae total flavone extract, the specific eutectic solvent is adopted, the ultrasonic technology is combined for extraction, the content of total flavone in the fructus psoraleae extract can be remarkably increased, and the fructus psoraleae total flavone can be efficiently extracted; and the adopted extraction solvent has the advantages of greenness, environmental protection, efficient process, low cost, high safety and the like, and can solve the problems of the existing extraction process. The malaytea scurfpea fruit total flavone extract obtained by the method has the effect of promoting hair growth and can remarkably promote hair follicle cell proliferation and prolong the hair growth period, the prepared external gel product has the hair growth effect, the preparation method is simple, and external use is convenient. The malaytea scurfpea fruit total flavone extract provided by the invention can be used for developing more cosmetics and medical products for preventing alopecia and promoting hair growth, and a new scheme is provided for green extraction of natural active ingredients and treatment of alopecia.

The invention discloses an application of a CsHCT1 gene in increasing the content of citrus flavonoids, belongs to the technical field of agricultural biological genetic engineering, and provides an application of the CsHCT1 gene in increasing the content of citrus flavonoids, and the nucleotide sequence of the CsHCT1 gene is as shown in SEQ ID NO.1. The invention further discloses an application of the CsHCT1 gene in increasing the content of citrus flavonoids. The invention also discloses a method for improving the flavone compound of the citrus peel by using the CsHCT1 gene. The method comprises the following steps: cloning the citrus CsHCT1 gene; a CsHCT1 overexpression vector is constructed; transforming the overexpression vector to agrobacterium tumefaciens to obtain an agrobacterium tumefaciens liquid; and injecting the CsHCT1 gene into the citrus fruit to obtain the CsHCT1 gene overexpressed citrus fruit. A new choice is provided for increasing the flavonoid compounds in the citrus peel, the content of vicenin-2 and / or hesperidin in the citrus peel is effectively increased, and the application has great application value for cultivating new functional citrus varieties and accelerating the breeding process.

The invention belongs to the technical field of hair care products, and particularly relates to composite acid gel for scalp care and a preparation method thereof. Salicylic acid, glycolic acid, piroctone azelate olamine salt, echinacea purpurea-lactic acid bacteria yeast, an emulsifier and water are combined, wherein the echinacea purpurea-lactic acid bacteria yeast is prepared by performing enzymolysis on echinacea purpurea through bacillus subtilis protease and then performing aerobic fermentation with lactic acid bacteria. Salicylic acid, glycolic acid and azelaic acid in the composite acid gel are compounded, so that stimulation of salicylic acid is weakened, and the effect of dissolving hair follicle grease is reserved; glycolic acid and azelaic acid are added to accelerate keratin metabolism, regulate sebum secretion and create safe and healthy shielding for the scalp environment, and polysaccharide and flavonoid compounds in the echinacea purpurea-lactic acid bacteria leavening are beneficial to exerting the anti-oxidation and immune regulation effects of the echinacea purpurea-lactic acid bacteria leavening. Therefore, the composite acid gel provided by the invention is green, safe and non-irritant, the preparation method is simple and convenient, and the composite acid gel can be used for inhibiting bacteria and reducing scalp inflammation.

A method for improving health conditions of mammals or livestock by feeding, to the mammals or livestock, a licorice extract including: (A) glycyrrhizic acid, a glycyrrhizic acid derivative, glycyrrhetinic acid, and / or a glycyrrhetinic acid derivative; (B) licorice saponins other than (A); and (C) licorice flavonoids; (B) including at least a licorice saponin H2, a licorice saponin G2, and macedonoside A, (C) including at least liquiritin apioside, isoliquiritin apioside, and isoliquiritin, where feeding is of 0.017 g / day / head or more of the licorice saponin H2, 0.002 g / day / head or more of the licorice saponin G2, and 0.002 g / day / head or more of the macedonoside A, 0.001 g / day / head or more of the liquiritin apioside, 0.001 g / day / head or more of the isoliquiritin apioside, and 0.001 g / day / head or more of the isoliquiritin.

The invention discloses a FaABI3 gene and application thereof in regulation and control of strawberry fruit maturity and strawberry flavonoid content, and relates to the field of gene engineering, the nucleotide sequence of the FaABI3 gene is shown as SEQ ID NO.1, and the amino acid sequence of protein encoded by the FaABI3 gene is shown as SEQ ID NO.2. A FaABI3 gene silencing vector is constructed and is used for infecting octaploid strawberry fruits in a small green period, so that the strawberry fruit maturity and strawberry flavonoid content can be regulated and controlled, and the strawberry fruit maturity and strawberry flavonoid content can be regulated and controlled. Strawberry fruits with the FaABI3 gene silenced are obtained through screening according to the gene expression quantity in the fruits, it is indicated that by changing the expression quantity of the FaABI3 gene in strawberries, the growth and development of the strawberries can be regulated and controlled, the FaABI3 gene can be applied to strawberry genetic breeding, an important foundation is laid for strawberry variety improvement, and the method has a wide application prospect. The application of the FaABI3 gene in increasing the content of strawberry flavonoid spinosin, sophoricoside, formononin and delphinidin is found for the first time, and further understanding of a strawberry flavonoid regulation mechanism is facilitated, so that the strawberry flavonoid content can be regulated by utilizing a biotechnological means, and an important foundation is laid for strawberry variety improvement.

The invention discloses an edible and medicinal composition for dispelling effects of alcohol and protecting liver as well as a preparation method and application thereof, and belongs to the technical field of functional foods. The composition consists of the following raw materials in parts by weight: 1-8 parts of ampelopsis grossedentata extract freeze-dried powder, 1-8 parts of astragalus membranaceus extract freeze-dried powder, 1-5 parts of kudzu vine root extract freeze-dried powder, 1-8 parts of hawthorn extract freeze-dried powder and 1-5 parts of cassia seed extract freeze-dried powder. The composition is designed according to a multi-component synergistic interaction principle, and the functions of protecting the liver and dispelling the effects of alcohol are enhanced through targeted interaction of active ingredients such as ampelopsis grossedentata flavone, puerarin and astragaloside; the compound preparation has the compound effects of protecting the liver, dispelling the effects of alcohol, resolving dampness, resisting oxidative stress, regulating lipid metabolism and the like, can remarkably relieve the problems of acute and chronic liver injury and metabolic disorder caused by alcohol intake, and meets the food-grade safety standard and the medicinal activity requirement; the important application prospect is realized in the aspect of preparing a preparation for relieving alcoholic liver injury and improving the liver detoxification function.

The invention provides tartary buckwheat herbal baijiu and a preparation method thereof.The method aims at solving the problems that existing tartary buckwheat baijiu is lost in active ingredient, single in flavor and unstable in baijiu body, firstly, tartary buckwheat submicron powder, radix puerariae submicron powder and rhizoma polygonati submicron powder are put into Maotai-flavor base liquor together, and two-section type closed extraction is conducted at the normal temperature and then at the low temperature, adding a part of citric acid solution to adjust the pH at the initial stage of extraction; squeezing and filtering extract liquor, immediately adding bamboo leaf extract and phytic acid to carry out synergistic anti-oxidation treatment, and carrying out short-term aging; and finally, blending with the residual base wine. According to the preparation method disclosed by the invention, the retention rate of active ingredients such as tartary buckwheat flavone and the stability of the wine body are remarkably improved through staged extraction and dual antioxidant protection, the wine body is successfully endowed with coordinated baking fragrance, sauce fragrance and herbal flavor, and the taste is mellow and mild.

The invention discloses a supercritical entrainment extraction device for total flavonoids in folium cortex eucommiae, and relates to the technical field of pharmaceutical production. Comprising a fluid supply mechanism and an extraction mechanism, the fluid supply mechanism comprises a material mixing tank, a stirring pipe is rotatably arranged in the material mixing tank, a plurality of strip-shaped shells are fixedly arranged on the surface of the stirring pipe, and a plurality of nozzles are fixedly embedded in the surfaces of the strip-shaped shells. A dispersing disc and a grinding roller are arranged in the extraction tank, eucommia ulmoides leaves on the surface of the dispersing disc can be ground and smashed, and meanwhile, supercritical carbon dioxide mixed fluid is sprayed to the surfaces of the eucommia ulmoides leaves on the surface of the dispersing disc through a spray head on the surface of a rotating arm, so that the mixed fluid and the eucommia ulmoides leaves fully react; by utilizing the dissolving capacity of the supercritical carbon dioxide mixed fluid, a worker can conveniently extract the total flavonoids from the folium cortex eucommiae dissolved solution, so that the residual of solvent toxicity under the traditional solvent extraction condition can be effectively avoided, and meanwhile, the poison to a human body and the pollution to the environment in the extraction process are also prevented.

The invention discloses Kluffa yeast and application of the Kluffa yeast in preparation of red camellia fermentation liquor with anti-aging and repairing functions, the Kluffa yeast is used for repairing PR-LQX002, the Latin name of the Kluffa yeast is Lachancea kluyveri, and the preservation number of the Kluffa yeast is CCTCC NO: M 20241723. The invention also provides a red camellia fermentation broth, a composition containing the fermentation broth and application of the red camellia fermentation broth in preparation of products with anti-oxidation, anti-saccharification, anti-wrinkle or repair effects. The fermentation broth is prepared from the following raw materials: red camellia flowers, red camellia leaves and Kluffa yeast PR-LQX002. The Kluffa yeast can greatly promote fermentation of flowers and leaves of the red camellia, and the obtained red camellia fermentation liquor not only contains active substances such as flavone, polyphenol and free amino acid, but also contains lipid substances such as ceramide, and has multiple effects such as saccharification resistance, repair, wrinkle resistance and oxidation resistance.

The additive 50 is used alone as a tablet or capsule, or together with a base product 54, to produce an enhancing product 52 that provides a health benefit 34 to a person 20 ingesting or using the additive 50, the additive 50 including an enzyme that stimulates the naturally occurring in the human body. The additive 50 has one or more hydrogenated substances 58, such as erythritol 58a, xylitol 58b, hydrogenated dihydromyricetin 58c and / or quercetin dihydrate 58d, and a flavonoid dihydromyricetin 14a. The flavonoid 14 may be extracted from Ampelopsis grossedentata plant 17 and / or a plant 16 selected from the genus Hovenia (e.g., Japanese raisin tree). The additive may also have one or more solvents 60, such as a bicarbonate compound 60a or an alcohol solvent 60b, a pH balanced acid 62, and / or a preservative 64. The base product 54 may be a liquid 66, a solid 68, a powder 70, a chew 72, a medicament 74, a cosmetic 76, or an emulsion or other coating product 78. The reinforced product 52 is a base product 54 reinforced by an additive.

The invention discloses an icaritin carbamate prodrug as well as a preparation method and application thereof, belongs to the field of pharmacy, and particularly relates to an icaritin carbamate prodrug as shown in a formula 3-N or 7-N and pharmaceutically acceptable salts thereof as well as a preparation method and application of the icaritin carbamate prodrug. Specifically, a main metabolic site (3-site or 7-site hydroxyl) of a natural flavone compound icaritin is subjected to structural modification through a chemical synthesis method, and an appropriate group is introduced into the site to form the icaritin carbamate prodrug. Amines adopted by the carbamate are aliphatic amines. Due to existence of a carbamate structure, II-phase metabolism of icaritin in SD rats is reduced, compared with icaritin raw material medicine, the 3-N-01 prodrug has the advantages that oral bioavailability is remarkably improved, the 3-N-01 prodrug is the optimal prodrug, clinical medication is expected to be capable of reducing administration dosage and improving patient compliance, and the 3-N-01 prodrug can be applied to preparation of the SD rats. And an effective strategy is expected to be provided for improving the oral bioavailability of phenolic drugs. # imgabs0 #

The invention discloses a method for extracting total flavonoids from Chinese redbud seeds, and belongs to the technical field of natural product extraction and separation. The method adopts a deep eutectic solvent (DES) as an extraction medium, and specifically comprises the following steps: mixing dried Chinese redbud seed powder with the DES, carrying out ultrasonic-assisted extraction, and then carrying out centrifugal separation; and purifying the extracting solution by using macroporous adsorption resin, and eluting by using distilled water and ethanol in sequence to finally obtain the total flavonoids. According to the invention, cyclic utilization of the DES solvent is innovatively realized, DES in the loading effluent and the distilled water eluent is recovered through evaporation, and the DES solvent can be repeatedly used for at least three times. Compared with a traditional ethanol reflux extraction method, the method has the remarkable advantages that the total flavone extraction amount is increased by 3 times, and the method is simple and convenient in operation process, high in safety, environment-friendly and low in cost. The method not only improves the extraction efficiency, but also meets the requirements of modern green processing, and provides a new technical approach for sustainable development of natural products.

The invention discloses a gene for regulating and controlling taro flavone biosynthesis and application thereof, and belongs to the technical field of biology. The gene comprises a CeHCT1 gene and a CeHCT2 gene; the nucleotide sequence of the CeHCT1 gene is as shown in SEQ ID NO. 9; and the nucleotide sequence of the CeHCT2 gene is as shown in SEQ ID NO. 10. The invention also provides application of the gene in regulation and control of taro flavone content and improvement of plant nutritional quality. The CeHCT1 and / or CeHCT2 genes of the main cultivated variety Xinhua Longxiang taro are / is subjected to multi-target knockout through a gene editing technology, the flavonoid content in the taro can be effectively increased, the nutritional quality of the taro is efficiently enhanced, and the method has a great significance in accelerating development and utilization of taro genes and has a great application prospect. The method for improving the nutritional quality of the taros by applying a biological enhancement technology has important theoretical and practical significance.

The invention relates to a flavonoid active fraction of an Abelmoschi corolla, a preparation method and an application thereof, and belongs to the field of traditional Chinese pharmaceutics. A high-purity Abelmoschi corolla flavonoid active fraction is prepared, which is found to have better therapeutic activity for kidney disease, and especially have a significant therapeutic effect for diabetic kidney disease and lupus nephritis, or contrast-induced kidney injury and eye diseases. Meanwhile, the Abelmoschi corolla flavonoid active fraction described in the invention also has good safety.

The invention provides a microorganism synergistic nitrogen fixation fertilizer based on flavone induction and a preparation method thereof, and belongs to the technical field of agricultural fertilizers. The fertilizer induces the formation of an azotobacter biofilm through a flavonoid compound, promotes the colonization and nitrogen fixation of rhizosphere azotobacter, improves the nitrogen supply capability of soil, and reduces the dependence on chemical nitrogen fertilizer. The fertilizer comprises the following components: 5-15% of a flavone extract, 3-8% of an azotobacter, 20-30% of an organic carrier, 30-40% of an inorganic nutrient medium and 5-15% of a filler. The preparation method comprises the following steps: mixing the organic carrier and the inorganic nutrient substrate, adding the filling agent, granulating, adding the nitrogen-fixing bacterial agent and the flavone extract to form a composite liquid, spraying the composite liquid, drying and packaging. Compared with the prior art, the fertilizer disclosed by the invention has the advantages of remarkably improving the nitrogen fixation efficiency, reducing the use of chemical nitrogen fertilizer, enhancing the slow release performance, improving the fertilizer utilization rate, improving the soil ecological environment and promoting the healthy growth of plants. The method is simple, efficient and suitable for large-scale production and application.

The invention relates to the technical field of preparation methods of giant salamander peptide and eucommia ulmoides male flower tablets, in particular to a preparation method of giant salamander peptide and eucommia ulmoides male flower tablets. The giant salamander peptide and eucommia ulmoides male flower tablets comprise the following raw materials in parts by weight: 30-40 parts of giant salamander peptide powder, 20-25 parts of eucommia ulmoides male flowers, 10-15 parts of rape pollen, 10-15 parts of sea cucumber intestine peptide powder, 10-12 parts of a filler, 3-5 parts of an adhesive and 1-3 parts of a lubricant. According to the invention, the eucommia male flower contains geniposidic acid, chlorogenic acid, aucubin lignin, iridoid and phenylpropanoid natural active nutrient substances, flavonoid compounds, polysaccharide and other bioactive substances in the rape pollen, polysaccharide and peptide components in the sea cucumber intestine peptide powder, and the like. The andrias davidianus peptide powder is added into the andrias davidianus peptide powder, the andrias davidianus peptide powder cooperates with antioxidant peptide and immunomodulatory peptide in the andrias davidianus peptide powder to jointly form a rich bioactive substance library, and the components regulate the physiological functions of the human body from different angles, provide comprehensive nutrition support for the body and improve the fatigue resistance of the human body.

The invention relates to the field of shampoo preparation, and particularly discloses a preparation method of anti-hair-loss, hair-growth and oil-control shampoo based on plant active ingredients, which comprises the following steps: step 1, soaking folium artemisiae argyi and pepper in warm water of 50-60 DEG C for 30 minutes, decocting for 30 minutes with medium fire, and filtering to obtain a first extracting solution; the preparation method comprises the following steps: soaking soapberry, cacumen biotae, duckweed, fructus cnidii, fructus kochiae, angelica sinensis, radix rehmanniae, radix paeoniae alba, rhizoma atractylodis macrocephalae, coptis chinensis, golden cypress, scutellaria baicalensis, radix sophorae flavescentis and ligusticum wallichii for 2 hours, and decocting at 95-100 DEG C for 4 hours; a functional closed loop of'oil control purification-hair follicle activation-inflammation blocking 'is formed through a three-element synergistic mechanism of sapindus, cacumen biotae and duckweed, sapindus saponin constructs microenvironment balance through targeted removal of hair follicle fat suppository, cacumen biotae flavone activates a hair papilla cell proliferation signal channel, duckweed polysaccharide forms an anti-inflammatory protection barrier, and the anti-inflammatory effect is achieved. The three components form a three-dimensional protective network on the molecular level, so that the pathological process of seborrheic alopecia is effectively blocked.

The invention discloses a SiERF109 gene for regulating drought resistance, salt tolerance and flavonoid accumulation of millet and application of the SiERF109 gene, and belongs to the technical field of plant breeding. According to the invention, a gene SiERF109 with a nucleotide sequence shown as SEQ ID NO.1 is separated and cloned from millet, and fluorescent quantitative expression analysis shows that SiERF109 participates in drought and salt stress response of millet. After the gene is over-expressed in foxtail millet, in drought and salt stress experiments, compared with a wild type strain, the survival rate and chlorophyll content of a strain over-expressed with the SiERF109 gene are remarkably increased, the flavonoid content is increased by 33.5%-39.5%, and active oxygen accumulation is remarkably reduced; it is shown that the SiERF109 gene and the protein coded by the SiERF109 gene can remarkably improve the drought resistance, the salt resistance and the flavonoid content of the plant.

The invention provides a traditional Chinese medicine composition for resisting gastric mucosal lesion as well as a preparation method and application thereof. The preparation method comprises the following steps: S1, performing vacuum drying on the red-knees herb and the daphniphyllum calycinum, crushing to obtain mixed powder, and collecting dry condensate water for later use; s2, dry condensate water and compound enzyme are mixed to prepare enzymatic hydrolysate, the enzymatic hydrolysate is evenly sprayed to the mixed powder, then enzymolysis is conducted, and an enzymolysis mixture is obtained; s3, adding the enzymolysis mixture into an aqueous two-phase extraction solvent, performing ultrasonic extraction, filtering, centrifuging, taking supernate, performing vacuum concentration, eluting with macroporous adsorption resin, collecting eluent, performing vacuum concentration, and performing low-temperature vacuum drying to obtain the traditional Chinese medicine composition. According to the method, the red-knees herb and the daphniphyllum calycinum are subjected to ultrasonic extraction through the combination of proper enzymolysis and an aqueous two-phase extraction solvent, so that the dissolution of total flavonoid substances can be enhanced, the total flavonoid substances can be prevented from being damaged, the extraction yield of the total flavonoid substances is increased, and the extraction time is effectively shortened. The prepared traditional Chinese medicine composition can also obviously relieve gastric mucosal lesion and is good in acting effect.

The invention relates to the technical field of medicine preparation, in particular to a preparation method of licoflavone. The preparation method comprises the following steps: providing a licorice raw material, crushing, sieving, and carrying out solid-state fermentation to obtain licorice powder after solid-state fermentation; the preparation method comprises the following steps: adding a first mixed organic solution into a reaction kettle, soaking, adding a second mixed organic solution into the first mixed aqueous solution again, soaking, adding a second mixed organic solution, extracting, collecting an organic phase, carrying out enzymolysis enzyme deactivation and impurity removal on a solid product, and adding the second mixed organic solution again for extracting; and combining the organic phases, dialyzing, purifying and concentrating to obtain the licoflavone.

The invention relates to a polygonatum cyrtonema fresh rhizome processing quality grade evaluation method, which is characterized in that a production enterprise only needs to detect seven content values of polysaccharides, total saponins, total phenols, total flavonoids, reducing sugar, crude protein and crude fat of processed polygonatum cyrtonema rhizomes by themselves or entrusting a third-party mechanism, and then can calculate and evaluate by themselves; the method is simple and easy to learn, convenient to operate, high in precision, high in efficiency and low in cost, can be widely applied to quality self-evaluation of edible polygonatum cyrtonema production enterprises and separation of superior and inferior products, is beneficial to grading sales of edible polygonatum cyrtonema products, improves the added value of the products, and meets the demand of consumers for purchase according to needs.