654 results about "Flavonoid" patented technology

The invention belongs to the technical field of hair care products, and particularly relates to composite acid gel for scalp care and a preparation method thereof. Salicylic acid, glycolic acid, piroctone azelate olamine salt, echinacea purpurea-lactic acid bacteria yeast, an emulsifier and water are combined, wherein the echinacea purpurea-lactic acid bacteria yeast is prepared by performing enzymolysis on echinacea purpurea through bacillus subtilis protease and then performing aerobic fermentation with lactic acid bacteria. Salicylic acid, glycolic acid and azelaic acid in the composite acid gel are compounded, so that stimulation of salicylic acid is weakened, and the effect of dissolving hair follicle grease is reserved; glycolic acid and azelaic acid are added to accelerate keratin metabolism, regulate sebum secretion and create safe and healthy shielding for the scalp environment, and polysaccharide and flavonoid compounds in the echinacea purpurea-lactic acid bacteria leavening are beneficial to exerting the anti-oxidation and immune regulation effects of the echinacea purpurea-lactic acid bacteria leavening. Therefore, the composite acid gel provided by the invention is green, safe and non-irritant, the preparation method is simple and convenient, and the composite acid gel can be used for inhibiting bacteria and reducing scalp inflammation.

The invention provides tartary buckwheat herbal baijiu and a preparation method thereof.The method aims at solving the problems that existing tartary buckwheat baijiu is lost in active ingredient, single in flavor and unstable in baijiu body, firstly, tartary buckwheat submicron powder, radix puerariae submicron powder and rhizoma polygonati submicron powder are put into Maotai-flavor base liquor together, and two-section type closed extraction is conducted at the normal temperature and then at the low temperature, adding a part of citric acid solution to adjust the pH at the initial stage of extraction; squeezing and filtering extract liquor, immediately adding bamboo leaf extract and phytic acid to carry out synergistic anti-oxidation treatment, and carrying out short-term aging; and finally, blending with the residual base wine. According to the preparation method disclosed by the invention, the retention rate of active ingredients such as tartary buckwheat flavone and the stability of the wine body are remarkably improved through staged extraction and dual antioxidant protection, the wine body is successfully endowed with coordinated baking fragrance, sauce fragrance and herbal flavor, and the taste is mellow and mild.

The invention discloses a method for synergistically extracting flavonoid compounds in epimedium wushanense by combining a ternary eutectic solvent with in-situ ultrasound, which is characterized in that choline bitartrate-urea-glycerol (Chb: Ure: Gly) is used as the ternary eutectic solvent, and the flavonoid compounds in epimedium wushanense are synergistically extracted by the in-situ ultrasound. The method is high in extraction speed and good in repeatability, solvent consumption can be reduced, operation steps are simplified, and efficiency is improved.

The invention belongs to the technical field of biosynthesis of plant secondary metabolites, and particularly relates to a key gene for biosynthesis of large-fruit hawthorn flavonoid compounds and a screening method and application of the key gene. Through combined analysis of metabolome and transcriptome, a key gene combination containing seven structural genes and three transcription factor genes is screened out; the expression of the genes is remarkably positively correlated with the accumulation of a target flavone metabolite [6]-gingerol, and the genes are core factors for regulating and controlling the synthesis of the flavonoid compounds of the big-fruit hawthorns through experimental verification. According to the invention, the key gene for regulating and controlling the synthesis of flavone substances such as [6]-gingerol in the big hawthorn fruit is systematically identified for the first time, and a target spot is provided for analyzing a quality formation mechanism from a molecular level; the gene can be used for molecular marker-assisted breeding so as to cultivate a new variety of large-fruit hawthorn with high flavone content, and also can provide gene resources and technical support for the development of functional food and health care products.

The invention discloses an extraction method of rose flavonoids, which comprises the following steps: S1, crushing selected dry Hetian rose buds, and storing for later use; s2, accurately weighing 1g of rose powder and putting the rose powder into a conical flask; s3, then, according to the material-liquid ratio of 1: 40, 40% ethanol is used as a solvent, and the materials are poured into a conical flask to be mixed; and S4, finally, soaking in a constant-temperature water area, extracting for 2 hours, and finally, taking supernate for later use. According to the invention, the solid-liquid ratio of 1: 40 ensures that the rose powder is fully infiltrated by an enough solvent (40% ethanol). Under the proportion, the ethanol can be in full contact with target components (such as flavonoid compounds and the like) in the rose powder. Each 1g of rose powder is surrounded by 40ml of solvent, so that target components have more opportunities to be dissolved out of powder particles to enter the solvent, and the extraction completeness can be improved compared with the condition that a feed liquid is relatively small.

The invention relates to the technical field of biological medicine, in particular to anti-acne hydrogel and a preparation method thereof. The anti-acne hydrogel is prepared from metal-polyphenol network nanoparticles and a hydrogel base material, the metal-polyphenol network nanoparticles comprise a first polyphenol compound, a second polyphenol compound and metal ions, the first polyphenol compound is a tannic acid compound, and the second polyphenol compound is a flavonoid compound; the hydrogel base material comprises a hydrophilic high-molecular polymer and a cationic polymer. The metal-polyphenol network nano-particles are creatively utilized, the anti-inflammatory and anti-oxidation activity of flavonoid compounds, the convergence and protein binding characteristic of tannin and the antibacterial activity of metal ions are integrated at the same time, and the vicious circle of acne can be intervened at the same time from multiple links of antibacterial, anti-inflammatory, anti-oxidation and keratinization adjustment; and the defect of single action target spot of the existing medicine is overcome.

The invention belongs to the technical field of active substance extraction, and discloses a method for extracting boxthorn leaf total flavonoids through an ultrasonic-assisted deep-eutectic solvent and application of the boxthorn leaf total flavonoids. Heating and mixing the hydrogen bond acceptor and the hydrogen bond donor, stirring to be transparent, and adding water to reduce viscosity to obtain the eutectic solvent; mixing the boxthorn leaf powder with a deep-eutectic solvent, performing ultrasonic extraction and centrifugation, and collecting supernate; adsorbing by using macroporous resin, washing and desorbing to obtain an eluent; and performing vacuum freeze drying to constant weight. According to the method disclosed by the invention, the eutectic solvent with low melting point and strong solubility is selected, the flavonoid compounds in the boxthorn leaves are green and efficiently extracted, and the total flavonoid content of the boxthorn leaves obtained by taking the eutectic solvent as an extraction solvent is 123.94 + / -1.04 mg / g and is far higher than the total flavonoid content of the boxthorn leaves obtained by traditional ethanol extraction by 64.60 + / -0.87 mg / g; the method is good in safety, short in time consumption and high in extraction rate.

The present invention relates to the technical field of functional food products. Disclosed are a rose enzyme liquid and rose enzyme beverage for promoting emotional health, and a preparation method therefor. Sour cherry flesh, double-petaled red roses, roselle, and Perillae folium are subjected to a colloid mill, and water is added for extraction and separation to obtain a concentrate. The concentrate is fermented with Lactiplantibacillus plantarum and Bifidobacterium longum to obtain a rose enzyme liquid, and the rose enzyme liquid is compounded with a saffron extract, a Mentha spicata extract, a bamboo leaf flavonoid, etc. to obtain a rose enzyme beverage. The rose, roselle, sour cherry and Perillae folium, which are both medicinal and edible, are selected as raw materials. The raw materials are fermented by means of using specific probiotic strains to effectively release active ingredients, which are then converted into small molecular substances that are easily absorbed by the human body and relieve emotional anxiety. Moreover, functional ingredients comprising the saffron extract, the Mentha spicata extract and the bamboo leaf flavonoid are compounded to effectively relieve stress, regulate daily negative emotions, and promote physical and mental relaxation, and enhance mental well-being. The sour and sweet taste satisfies consumers' pursuit for flavor, taste and efficacy.

The invention relates to the technical field of cosmetics, in particular to a composition for promoting skin microcirculation as well as a preparation method and application thereof, and the key point of the technical scheme is that the composition consists of the following components: rhizoma bletillae, motherwort, poria cocos, moutan bark, ginseng, peach blossom and lotus. According to the composition, the deep-eutectic solvent is combined with a micro-jet extraction technology, so that the extraction efficiency of active ingredients such as flavonoids is remarkably improved, and functional ingredients for resisting oxidation, resisting aging and promoting blood circulation are effectively reserved. According to the composition disclosed by the invention, the comprehensive effects of improving skin microcirculation, relieving dark skin color and delaying senescence are systematically realized by efficiently extracting active substances, activating a microcirculation core pathway and cooperating with coherent effects of a whitening and repairing mechanism.

The invention discloses a method for predicting liquid chromatography retention time of traditional Chinese medicine active ingredients. The method comprises the following steps: detecting retention time of flavonoid compounds or anthraquinone compounds under different chromatographic conditions through a reverse high performance liquid chromatograph; performing structure optimization on the flavonoid compound or the anthraquinone compound; performing molecular descriptor calculation on the optimized compound structure to obtain a molecular descriptor data set; performing genetic algorithm screening on the molecular descriptor data set to obtain characteristic molecular descriptors; combining the characteristic molecule descriptors with the different chromatographic conditions into a complete data set; the complete data set serves as an input variable, retention time serves as an output variable, and a gradient elevator GB algorithm or a random forest method RF is adopted for modeling to obtain a QSRR model; and predicting the retention time of flavonoid or anthraquinone compounds under different chromatographic conditions by using the constructed QSRR model.

The application discloses application of total flavones of chrysanthemum morifolium ramat and metabolites thereof in preparation of uric acid-lowering or liver and kidney protecting drugs or health care products. The total flavones of chrysanthemum morifolium ramat contain various flavone compounds. In a hyperuricemia model mouse, the total flavones of chrysanthemum morifolium ramat can significantly reduce blood uric acid level, and has a significant protective effect on liver and kidney, and the effect is achieved by inhibiting the activity and expression of xanthine oxidase and adenosine deaminase in the liver, and regulating the expression of uric acid related transporters in the kidney. Meanwhile, metabolites of the total flavones of chrysanthemum morifolium ramat, luteolin-7-O-glucuronide and apigenin-7-O-glucuronide, can also play a pharmacological role in the mouse body. In vitro experiments and mouse primary hepatocytes further prove that luteolin-7-O-glucuronide and apigenin-7-O-glucuronide have an inhibiting effect on the activity and expression level of xanthine oxidase. The application widens the application range of traditional Chinese medicinal materials, and provides a new direction for development of efficient and low-toxic uric acid-lowering and anti-gout drugs or health care products.

This invention relates to the field of daily chemical products technology, and more particularly to a method for preparing and applying a cosmetic camel thorn extract. The method for preparing the cosmetic camel thorn extract includes: crushing camel thorns, adding an ethanol solution, performing ultrasonic extraction at least twice, combining the extracts, concentrating, and obtaining the extract. This invention, based on the distribution of active ingredients in the camel thorn extract, specifically targets and extracts the active components, thereby ensuring sufficient enrichment of active ingredients and guaranteeing the stability and reliability of the extract quality. The ultrasonic treatment and vacuum concentration processes improve production efficiency and reduce production costs. Furthermore, the extract contains a variety of active ingredients, including flavonoids, polysaccharides, and other compounds, significantly enriching the composition of the extract and enhancing the potential for product efficacy and application development.

The invention discloses a ginkgo natural extract copolymerized antibacterial conductive gel as well as a preparation method and application thereof. The conductive gel is prepared from the following raw materials in parts by mass: 1 to 10 parts of ginkgo natural extract, 1 to 8 parts of imidazolyl alkenyl amic acid compound, 0.02 to 0.1 part of stabilizer, 0.01 to 0.2 part of emulsifier, 0.5 to 1 part of organic silicon cross-linking agent, 1 to 5 parts of modifier, 0.05 to 0.3 part of organic oxidant, 1 to 10 parts of natural polysaccharide, 15 to 25 parts of organic solvent and 10 to 30 parts of water. The gingko natural extract has an antibacterial effect, micro-current is conducted by the gingko natural extract through a macromolecular chain and aromatic continuous conjugated structures in flavonoids and olefinic terpenoids, the antibacterial and conductive gel which is low in toxicity and can be applied to organism tissue repair is prepared, and the gel serving as a flexible medium can conduct electric signals and also can be used for repairing tissues of organisms. The foreign matter reaction risk can be reduced through the antibacterial function, meanwhile, the toxicity of metal ion leakage is avoided, and the method has unique advantages in the micro-current related fields such as flexible electronic sensors and bioelectrical stimulation dressings.

The invention belongs to the technical field of facility horticulture postharvest treatment, and particularly relates to a tomato postharvest quality regulation and control light supplementing system based on white light-metabolism key enzyme coupling activation and an application method thereof, and the tomato postharvest quality regulation and control light supplementing system comprises an enzyme activity targeting white light module, an enzyme activity feedback module and a fruit bearing regulation and control module. According to the postharvest tomato quality regulation and control light supplementing system based on white light-metabolic key enzyme coupling activation, a white light spectrum segmentation-key enzyme activity dynamic matching coupling mechanism is innovatively designed by combining the regulation and control rule of white light on the activity of key enzymes such as carotenoid synthetase and phenylpropane metabolic enzyme of tomato fruits; through an adjustable broad-spectrum white light source and an enzyme activity feedback module, directional accumulation of beneficial metabolites such as carotenoids and flavonoid compounds and efficient degradation of alkaloids are realized.

The invention belongs to the technical field of natural pharmaceutical chemistry, and discloses a flavonoid compound in lomatogonium radiatum as well as a preparation method and application thereof.The flavonoid compound is separated from lomatogonium radiatum of a gentiaceae lomatogonium plant, the medicinal material of lomatogonium radiatum is extracted and concentrated, and the flavonoid compound is obtained. And sequentially carrying out macroporous adsorption resin separation, gel column chromatography separation, medium-low pressure ODS column chromatography separation and semi-preparative high performance liquid chromatography separation. Pharmacological studies show that the compound provided by the invention can effectively inhibit the levels of COX2, IL-6 and TNF-alpha in mouse macrophages RAW246.7 caused by lipopolysaccharide (LPS), which indicates that the compound has obvious anti-inflammatory activity and can be used for preparing anti-inflammatory drugs.

The invention discloses an extraction process for optimizing general flavone of strobilanthes cusia through a response surface method. An ultrasonic extraction method is adopted to extract total flavonoids in strobilanthes cusia, on the basis of a single factor experiment, an extraction process of the strobilanthes cusia total flavonoids is optimized through a response surface method, and comprehensive experiment conditions, operability and rationality are considered, so that the optimal extraction process is obtained as follows: the material-liquid ratio is 1: 27, the ethanol concentration is 72%, the ultrasonic extraction time is 39 min, and the extraction time is 30 min; under the condition, the total flavone extraction rate reaches 0.736 + / -0.015% and is basically consistent with a response predicted value. The extraction process is simple and stable in operation and high in extraction rate. In-vitro anti-oxidation experiments show that the strobilanthes cusia total flavonoids have certain DPPH free radical and ABTS free radical scavenging capacity, and a reference basis is provided for more fully and reasonably utilizing strobilanthes cusia resources.

Aspects of disclosure relate to a composition and methodology for treating menopause symptoms utilizing a cannabinoid-based nanoplatform composition. The composition includes phytocannabinoids like CBD, CBG, and CBN, alongside isoflavones and polyphenols, all integrated into nanoplatform designed for enhanced bioavailability and controlled release. The formulation is designed to alleviate key menopause-related issues, including vasomotor symptoms (VMS), genitourinary syndrome of menopause (GSM), bone loss, mood disturbances, and sleep disorders, while addressing cardiovascular disease (CVD) risks. The composition combines cannabinoids, such as CBD, with isoflavones and polyphenols, and is incorporated into nanoplatforms for enhanced delivery and efficacy. Additionally, the disclosure includes a kit comprising oral capsules, intravaginal ovules, and instructions for use. The capsules contain a blend of cannabinoids, flavonoids, and polyphenols, while the ovules are composed of CBD and cocoa butter. The kit provides a comprehensive solution for managing menopause symptoms and mitigating cardiovascular risks.

The invention discloses a method for analyzing orange peel microbial community structure difference based on a high-throughput sequencing technology, which comprises the following steps: S1, standardized preparation of a sample: collecting orange peel, opening the orange peel, drying in the shade, turning the orange peel and sun-drying until the water content is less than or equal to 12% to obtain an orange peel sample; s2, crushing the orange peel sample, adding a buffer solution containing an impurity adsorbent, and performing water bath and centrifugation to remove flavonoid and polysaccharide impurities; extracting DNA by adopting a DNA extraction kit, and verifying the integrity and purity of the DNA; s3, designing primers for the specific high-resolution sequencing areas of bacteria and fungi, constructing a PCR system by using high-fidelity enzyme, performing amplification, and constructing a sequencing library after recovering target fragments; and S4, obtaining sequence data through a high-throughput sequencing platform, generating a flora feature table, calculating an Alpha diversity index to evaluate the community richness, analyzing and evaluating the community differentiation degree through Beta diversity, and screening core differential flora by adopting a standard that LDAscore is greater than 2. The efficient analysis on the structure difference of the orange peel microbial community is realized.

The invention relates to a green process for extracting natural components of pericarpium citri reticulatae with water and application of the natural components in a beverage. The process comprises the following steps: crushing and drying a dried orange peel raw material; extracting with water at 105-125 DEG C under 0.8-1.5 MPa under a low-oxygen condition to obtain a first extracting solution and first-stage residues; the residues are extracted at the temperature of 130-150 DEG C and the pressure of 1.5-2.2 MPa, and a second extracting solution is obtained; treating the second extracting solution at the temperature of 145-165 DEG C and the pressure of 1.8-2.5 MPa to obtain a low-ester pectin component containing bound flavone; mixing the first extracting solution with the low-methoxyl pectin component, and homogenizing, so that the volatile oil component is dispersed in the water phase containing the low-methoxyl pectin component; and concentrating and / or drying the obtained dispersion to obtain the pericarpium citri reticulatae extract. The extract can be used as a natural flavor additive for beverages.

The invention belongs to the technical field of biological medicines, and particularly discloses an anti-fatigue and joint protection composition for sports people, which comprises the following components in percentage by mass: 10-25% of citrus bioflavonoid, 5-15% of taurine, 15-30% of eggshell membrane powder, 2-8% of curcumin compound, 1-5% of citric acid and the balance of maltooligosaccharide. Under the synergistic interaction of the citrus bioflavonoid, the taurine, the eggshell membrane powder and the curcumin compound, the composition with excellent anti-fatigue and joint protection effects is obtained.

This invention discloses a method and product for preparing Pien Tze Huang herbal wine fermented on Cordyceps militaris culture medium, belonging to the field of health wine brewing technology. This method uses Cordyceps militaris culture medium (SCM) and Pien Tze Huang herbal wine (GFE) as raw materials, and prepares a health wine with hypoglycemic and antioxidant effects through a complex fermentation process including raw material pretreatment, enzymatic hydrolysis, yeast activation, anaerobic fermentation, and post-treatment. It aims to solve the problems of low raw material utilization, low active ingredient content, and insufficient antioxidant activity in existing technologies. Pretreatment employs ultrasonic extraction. Fermentation conditions are anaerobic fermentation at 28℃ for 18 days, with 3% sugar supplementation every 2 days, controlling the alcohol content at 6%-10% vol, and preferably using an SCM:GFE ratio of 2:1. The resulting product has an alcohol content of 8% vol, is rich in total phenols and total flavonoids, has an α-glucosidase inhibition rate of 82.6%, a DPPH free radical scavenging rate of 78.3%, and a FRAP value of 82.6 mM Fe. 2+ Equivalents / mL, with a harmonious flavor and significant health benefits, provide an effective way for the comprehensive development of Cordyceps militaris and Pien Tze Huang.

This invention provides a drug-coated balloon catheter, its preparation method, and its application, relating to the field of medical device technology. The drug-coated balloon catheter includes a balloon catheter and a drug coating disposed on the surface of the balloon catheter; the drug coating includes an active drug and an excipient; the active drug is a flavonoid. The drug-coated balloon catheter utilizes flavonoids, which combine the advantages of low toxicity and high water solubility. While reducing the toxic side effects of the drug coating, it achieves rapid release and efficient absorption of the drug. Furthermore, through a dual mechanism of anti-proliferation and anti-inflammation, it effectively solves the problems of potential toxic side effects, limited transport efficiency, and limited functionality that may exist in existing products at high dose densities.

The invention relates to the technical field of agricultural product processing, in particular to a preparation method and application of high-activity medicinal and edible lily tea drink dried flowers. The method solves the problem that active ingredients such as flavonoids, aromatics, steroid saponins and alkaloids are easy to lose in the existing dried lily preparation. In the prepared dried medical lily flowers, the relative concentration of honeysuckle glycoside is larger than or equal to 1460 micrograms / g, the relative concentration of benzene and substituted derivatives thereof is larger than or equal to 960 micrograms / g, the relative concentration of steroid sapogenin-O-glucose is larger than or equal to 2120 micrograms / g, the relative concentration of choline is larger than or equal to 699 micrograms / g, the medical value and edible quality of the dried medical lily flowers are remarkably improved, and the method is suitable for large-scale production.

The application discloses an evaluation method for distinguishing different quality of momordica grosvenori of different origins. The application adopts high performance liquid chromatography to establish the fingerprint of momordica grosvenori, carries out gradient elution by taking water-acetonitrile as a mobile phase, and detects the wavelength of 203 nm to obtain the HPLC fingerprint of momordica grosvenori; the obtained chromatogram is introduced into a traditional Chinese medicine chromatographic fingerprint similarity evaluation system to generate a control fingerprint, different origins of momordica grosvenori are distinguished through similarity comparison and / or chemical pattern recognition analysis; and chemical markers with VIP>1 such as 5-hydroxymethyl furfural, momordica grosvenori flavonoid, momordica grosvenori saponin V and momordica grosvenori saponin IIIA2 are screened. The application can effectively distinguish two main origins of green skin fruit and red hair fruit, overcomes the defects that traditional trait identification is subjective and it is difficult to distinguish similar appearance samples, and provides an objective, accurate and stable technical means for origin identification, quality consistency evaluation and authenticity identification of momordica grosvenori.

The application discloses a kind of detection flavonoid compound magnetic composite material, preparation, detection method and the application of preparation standard substance, belong to analytical chemistry technical field.Magnetic composite material includes magnetic nanoparticle core, double lanthanide series metal organic framework (MOF) first shell and covalent organic framework (COF) second shell successively coated on its surface, and phenylboronic acid group grafted on the surface of second shell.The material uses the specific covalent binding of phenylboronic acid and the characteristic ortho-diphenol hydroxyl group of flavonoid compound to realize efficient capture and enrichment;Through double lanthanide series MOF shell, promote energy transfer, COF shell provides high specific surface area and ordered diffusion channel, and magnetic core is convenient for rapid separation, which realizes high selectivity identification of flavonoid compound.The material has the advantages of high sensitivity, strong anti-matrix interference ability, rapid and simple detection, etc., and is suitable for accurate analysis of flavonoid compound in complex sample and development of related standard substance.

This invention discloses an optimized extraction and purification process for total flavonoids from Hypericum perforatum and its application in photodamage protection. Belonging to the field of natural product extraction technology, the process includes the following steps: using Hypericum perforatum powder as raw material, ultrasonic-assisted extraction is performed, followed by centrifugation, collection of the supernatant, and repeated extraction of the residue twice. The supernatants are combined to obtain a total flavonoid extract from Hypericum perforatum. The extract is then purified by adsorption using a macroporous adsorption resin, and the eluent is collected, concentrated, and dried to obtain high-purity total flavonoids from Hypericum perforatum. This invention features a stable process, high extraction efficiency, and is environmentally friendly, making it suitable for industrial production. The prepared total flavonoids from Hypericum perforatum exhibit high purity and significant antioxidant and photoprotective effects, and can be widely used in antioxidant, skin protection, and sunscreen products.

The invention discloses a separation and purification method of total flavonoids of mesembryanthemum crystallinum, which comprises the following specific steps: firstly, washing, drying and crushing fresh mesembryanthemum crystallinum to obtain dry mesembryanthemum crystallinum powder; adding the dried mesembryanthemum crystallinum powder into an ethanol water solution, performing ultrasonic extraction to obtain a mesembryanthemum crystallinum total flavone extracting solution, and performing freeze-drying to obtain a mesembryanthemum crystallinum total flavone crude extract; and selecting HPD-722 type macroporous resin, and carrying out dynamic adsorption elution on the mesembryanthemum crystallinum total flavone crude extract to obtain a mesembryanthemum crystallinum total flavone refined product. The mesembryanthemum crystallinum total flavonoids with high purity are separated and purified from fresh mesembryanthemum crystallinum, the purity of the mesembryanthemum crystallinum total flavonoids before and after a dynamic separation and purification test is improved by more than three times, and the purification effect is ideal.

This invention discloses a method for blanching and drying honeysuckle and its application, relating to the field of traditional Chinese medicine processing technology. The method includes: microwaving fresh honeysuckle with a power of 300-350 kW for 3-5 minutes; followed by drying the blanched honeysuckle at 80-90℃ for 3-5 hours. This invention, by employing a high-power microwave blanching combined with constant-temperature drying, significantly improves the retention rate of core active ingredients such as chlorogenic acid, flavonoids, and polyphenols in honeysuckle, while also achieving excellent sensory quality. Testing showed that the honeysuckle prepared by this method contained chlorogenic acid ≥140 mg / g, flavonoids ≥80 mg / g, and polyphenols ≥22 mg / g, with a weighted sensory evaluation score ≥90 points. The honeysuckle prepared by this method possesses excellent heat-clearing, detoxifying, antibacterial, anti-inflammatory, and antioxidant effects, making it suitable for continuous industrial production.

The invention belongs to the technical field of feed additives and preparation thereof, and discloses a preparation method and application of a hemerocallis citrina baroni extract for promoting lactation of sows, and the preparation method comprises the following steps: S1, selecting a hemerocallis citrina baroni raw material; s2, mixing the day lily with ethanol or pure water with the volume fraction of 80-95% according to the material-liquid ratio of (1: 5)-(1: 10), and performing reflux extraction; s3, combining the extracting solutions, filtering to remove impurities, and concentrating into thick paste; and S4, carrying out spray drying or vacuum drying treatment on the concentrated solution, and crushing the dried material to obtain daylily extract powder. The extracts are obtained from different parts of the day lily through a water extraction or alcohol extraction process, are rich in flavonoid and hydroxy fatty acid active ingredients, can significantly improve the lactation performance of sows and the weight of weaned piglets, and realize feed additive and industrial popularization and application in the field of animal husbandry.

The invention discloses a method for extracting flavonoid in apples, and belongs to the technical field of extraction and detection of plant active ingredients, a smashing shell is included, a feeding hopper is arranged at the upper end of the smashing shell, a screen is arranged in the smashing shell, a connecting rod is arranged at the lower end of the side edge of the smashing shell, and a centrifugal box is arranged at the other end of the connecting rod; a crushing mechanism is arranged at the upper end of the side edge of the crushing shell, a material taking mechanism is arranged at the lower end in the crushing shell, and a centrifugal mechanism is arranged in the centrifugal box. The crushing mechanism is arranged, a first motor drives a driven gear to rotate reversely through a driving gear, a first crushing roller and a second crushing roller roll oppositely for shearing, freeze-dried apple blocks are crushed instantly, dry powder with the particle size smaller than or equal to 0.425 mm is screened out on line through a screen, crushing and screening are integrally completed, particles are uniform, the extraction rate is stable, uneven manual grinding and dust flying are avoided, and the production efficiency is improved. Pretreatment standardization is achieved, a foundation is laid for follow-up efficient dissolution of flavonoids, and the detection reproducibility is remarkably improved.