1165 results about "Flavonoid" patented technology

The invention discloses a calendula double-bacterium fermentation product as well as a preparation method and application thereof, and relates to the technical field of plant fermentation. The preparation method of the calendula double-bacterium fermentation product disclosed by the invention comprises the following steps: carrying out primary fermentation by using lactobacillus plantarum, then carrying out secondary fermentation by using saccharomyces cerevisiae, and carrying out sterilization and filtration treatment on the calendula fermentation liquid subjected to secondary fermentation, so as to obtain the calendula fermentation liquid. The calendula fermentation liquor is subjected to combined fermentation through lactobacillus plantarum and saccharomyces cerevisiae, and the content of polyphenol and flavone in the calendula double-bacterium fermentation product is remarkably increased. Meanwhile, the calendula double-bacterium fermentation product has the effects of preserving moisture, resisting oxidation, relieving and controlling oil, and has a wide application prospect in the field of cosmetics.

The invention provides application of an enhanced and optimized mesenchymal stem cell exosome in knee osteoarthritis and muscle cartilage injury, and belongs to the technical field of biological medicine. The treatment activity of the umbilical cord mesenchymal stem cell exosome is remarkably improved by combining a composite pretreatment technology with a 3D culture system. Through the synergistic effect of the total flavonoids of rhizoma drynariae and tanshinone IIA, the pathological process of knee osteoarthritis can be regulated and controlled in multiple dimensions, including inflammatory reaction inhibition, cartilage repair promotion and joint function improvement, and the functional limitation of single-component pretreatment is broken through. The invention provides a safe and efficient novel treatment technical strategy for relieving knee osteoarthritis and muscle cartilage injury, and has a wide clinical application prospect.

The invention relates to a whitening and freckle-removing composition containing a composite plant extract and a preparation method of the whitening and freckle-removing composition, and belongs to the technical field of cosmetics. The composition disclosed by the invention is prepared from the following raw materials in parts by weight: 5 to 8 parts of pineapple leaf nano cellulose, 10 to 16 parts of modified starch, 10 to 15 parts of longan seed extract, 6 to 10 parts of mulberry bark extract, 5 to 8 parts of nicotinamide and 8 to 10 parts of hyaluronic acid. The pineapple leaf nanocellulose contains flavonoid and phenolic compounds with double-bond, conjugated double-bond and triple-bond structures, and modified starch is used as a filler to form a film on the surface of skin, so that an anti-ultraviolet protection wall is formed; the betaine-malate ionic liquid is added into the longan seeds, so that extraction of polyphenol in the longan seeds is improved, the longan seeds have acid-base buffering capacity, an auxiliary does not need to be added to adjust the pH value, the components of the prepared composition interact, and the whitening and freckle removing effects are achieved from multiple aspects of ultraviolet resistance, oxidation resistance, inflammation resistance and skin metabolism improvement.

The invention discloses a fructus psoraleae total flavone extract as well as a preparation method and application thereof in promoting hair growth. According to the preparation method of the fructus psoraleae total flavone extract, the specific eutectic solvent is adopted, the ultrasonic technology is combined for extraction, the content of total flavone in the fructus psoraleae extract can be remarkably increased, and the fructus psoraleae total flavone can be efficiently extracted; and the adopted extraction solvent has the advantages of greenness, environmental protection, efficient process, low cost, high safety and the like, and can solve the problems of the existing extraction process. The malaytea scurfpea fruit total flavone extract obtained by the method has the effect of promoting hair growth and can remarkably promote hair follicle cell proliferation and prolong the hair growth period, the prepared external gel product has the hair growth effect, the preparation method is simple, and external use is convenient. The malaytea scurfpea fruit total flavone extract provided by the invention can be used for developing more cosmetics and medical products for preventing alopecia and promoting hair growth, and a new scheme is provided for green extraction of natural active ingredients and treatment of alopecia.

The invention discloses an application of a CsHCT1 gene in increasing the content of citrus flavonoids, belongs to the technical field of agricultural biological genetic engineering, and provides an application of the CsHCT1 gene in increasing the content of citrus flavonoids, and the nucleotide sequence of the CsHCT1 gene is as shown in SEQ ID NO.1. The invention further discloses an application of the CsHCT1 gene in increasing the content of citrus flavonoids. The invention also discloses a method for improving the flavone compound of the citrus peel by using the CsHCT1 gene. The method comprises the following steps: cloning the citrus CsHCT1 gene; a CsHCT1 overexpression vector is constructed; transforming the overexpression vector to agrobacterium tumefaciens to obtain an agrobacterium tumefaciens liquid; and injecting the CsHCT1 gene into the citrus fruit to obtain the CsHCT1 gene overexpressed citrus fruit. A new choice is provided for increasing the flavonoid compounds in the citrus peel, the content of vicenin-2 and / or hesperidin in the citrus peel is effectively increased, and the application has great application value for cultivating new functional citrus varieties and accelerating the breeding process.

The invention belongs to the technical field of hair care products, and particularly relates to composite acid gel for scalp care and a preparation method thereof. Salicylic acid, glycolic acid, piroctone azelate olamine salt, echinacea purpurea-lactic acid bacteria yeast, an emulsifier and water are combined, wherein the echinacea purpurea-lactic acid bacteria yeast is prepared by performing enzymolysis on echinacea purpurea through bacillus subtilis protease and then performing aerobic fermentation with lactic acid bacteria. Salicylic acid, glycolic acid and azelaic acid in the composite acid gel are compounded, so that stimulation of salicylic acid is weakened, and the effect of dissolving hair follicle grease is reserved; glycolic acid and azelaic acid are added to accelerate keratin metabolism, regulate sebum secretion and create safe and healthy shielding for the scalp environment, and polysaccharide and flavonoid compounds in the echinacea purpurea-lactic acid bacteria leavening are beneficial to exerting the anti-oxidation and immune regulation effects of the echinacea purpurea-lactic acid bacteria leavening. Therefore, the composite acid gel provided by the invention is green, safe and non-irritant, the preparation method is simple and convenient, and the composite acid gel can be used for inhibiting bacteria and reducing scalp inflammation.

The invention provides tartary buckwheat herbal baijiu and a preparation method thereof.The method aims at solving the problems that existing tartary buckwheat baijiu is lost in active ingredient, single in flavor and unstable in baijiu body, firstly, tartary buckwheat submicron powder, radix puerariae submicron powder and rhizoma polygonati submicron powder are put into Maotai-flavor base liquor together, and two-section type closed extraction is conducted at the normal temperature and then at the low temperature, adding a part of citric acid solution to adjust the pH at the initial stage of extraction; squeezing and filtering extract liquor, immediately adding bamboo leaf extract and phytic acid to carry out synergistic anti-oxidation treatment, and carrying out short-term aging; and finally, blending with the residual base wine. According to the preparation method disclosed by the invention, the retention rate of active ingredients such as tartary buckwheat flavone and the stability of the wine body are remarkably improved through staged extraction and dual antioxidant protection, the wine body is successfully endowed with coordinated baking fragrance, sauce fragrance and herbal flavor, and the taste is mellow and mild.

The invention relates to the technical field of preparation methods of giant salamander peptide and eucommia ulmoides male flower tablets, in particular to a preparation method of giant salamander peptide and eucommia ulmoides male flower tablets. The giant salamander peptide and eucommia ulmoides male flower tablets comprise the following raw materials in parts by weight: 30-40 parts of giant salamander peptide powder, 20-25 parts of eucommia ulmoides male flowers, 10-15 parts of rape pollen, 10-15 parts of sea cucumber intestine peptide powder, 10-12 parts of a filler, 3-5 parts of an adhesive and 1-3 parts of a lubricant. According to the invention, the eucommia male flower contains geniposidic acid, chlorogenic acid, aucubin lignin, iridoid and phenylpropanoid natural active nutrient substances, flavonoid compounds, polysaccharide and other bioactive substances in the rape pollen, polysaccharide and peptide components in the sea cucumber intestine peptide powder, and the like. The andrias davidianus peptide powder is added into the andrias davidianus peptide powder, the andrias davidianus peptide powder cooperates with antioxidant peptide and immunomodulatory peptide in the andrias davidianus peptide powder to jointly form a rich bioactive substance library, and the components regulate the physiological functions of the human body from different angles, provide comprehensive nutrition support for the body and improve the fatigue resistance of the human body.

The invention discloses a SiERF109 gene for regulating drought resistance, salt tolerance and flavonoid accumulation of millet and application of the SiERF109 gene, and belongs to the technical field of plant breeding. According to the invention, a gene SiERF109 with a nucleotide sequence shown as SEQ ID NO.1 is separated and cloned from millet, and fluorescent quantitative expression analysis shows that SiERF109 participates in drought and salt stress response of millet. After the gene is over-expressed in foxtail millet, in drought and salt stress experiments, compared with a wild type strain, the survival rate and chlorophyll content of a strain over-expressed with the SiERF109 gene are remarkably increased, the flavonoid content is increased by 33.5%-39.5%, and active oxygen accumulation is remarkably reduced; it is shown that the SiERF109 gene and the protein coded by the SiERF109 gene can remarkably improve the drought resistance, the salt resistance and the flavonoid content of the plant.

The invention discloses preparation and application of an arundina graminifolia fermentation extract. The arundina graminifolia is fermented by adopting saccharomyces cerevisiae, so that the yield of total polyphenol (increased by 119.1%) and the yield of flavone (increased by 43.8%) in an arundina graminifolia extracting solution can be remarkably increased. The content of soluble solids in the obtained fermentation broth is 9.12 mg / mL, and the fermentation broth has acetylcholin esterase inhibitory activity (IC50 is 4.0 mg / mL) and oxidation resistance (the free radical scavenging rates IC50 of ABTS and DPPH are 0.116 mg / mL and 16.2 [mu] g / mL respectively); the fermentation liquor is high in sensory evaluation and palatability, and can be applied to nerve health maintenance in the field of homology of medicine and food as well as antioxidant functional beverages and health care products.

The invention belongs to the technical field of biological bacterial fertilizers, and discloses a Chinese herbal medicine carrier-based multifunctional microbial bacterial fertilizer, which comprises a microbial strain group, a Chinese herbal medicine active component group, an organic matter and nutrition carrier, mineral elements and auxiliary components, and a functional synergist. Through the synergistic interaction of Chinese herbal medicine active ingredients and functional microbial flora, breeding of harmful bacteria in soil is inhibited, synthesis of acetylcholin esterase of nematodes is interfered, a continuous cropping disease occurrence chain is blocked from the source, and meanwhile, organic acid and flavonoid substances slowly released by a Chinese herbal medicine carrier are utilized to activate resistance gene expression of a plant system, so that the disease resistance of the nematodes is improved. The tolerance threshold of crops to high temperature, cold damage and diseases is enhanced; in the composite carrier, humic acid and diatomite are crosslinked through hydrogen bonds to form a stable granular structure, the cation exchange capacity and porosity of soil are effectively improved, the strong hydration capacity of polyglutamic acid is combined to lock nutrients and moisture, and development of meristem of a root system and proliferation of capillary roots are promoted.

The invention belongs to the technical field of microorganisms, and relates to a plant lactobacillus NXU-F1 strain and application thereof. The classification name of the bacterial strain is lactobacillus plantarum, the bacterial strain is preserved in Guangdong Microbial Culture Collection Center on June 20, 2025, and the preservation number of the bacterial strain is GDMCC No.66563. The invention also discloses a preparation method of the bacterial strain. The plant lactobacillus is strong in growth capability, has good adaptive capacity to environment, and can obviously increase the content of antioxidant substances when being applied to plant matrix fermentation. The lycium barbarum and grape compound fermented beverage is prepared by fermenting the lycium barbarum and grape compound fermented beverage, the content of polyphenol, flavone, polysaccharide and procyanidine in the beverage is obviously increased, and the increase of resveratrol and ferulic acid is particularly obvious; meanwhile, ester compounds are increased and aldehyde substances are reduced, so that the beverage is endowed with strong longan fruity flavor, and the flavor of harmonious sour and sweet taste and lingering aftertaste is formed.

The invention discloses targeted prebiotic plant extraction dietary powder for relieving hyperuricemia and a preparation technology of the targeted prebiotic plant extraction dietary powder, and belongs to the technical field of dietary powder.In a formula of the targeted prebiotic plant extraction dietary powder for relieving hyperuricemia, as a patented bacterial strain, the bacillus coagulans MKSWC01 can directly act on the intestinal tract environment, uric acid precursor substances generated by purine metabolism are degraded in a targeted mode, and generation of uric acid is reduced from the source; the chicory root superfine powder and the mulberry leaf DNJ extract respectively activate kidney excretion protein, inhibit the activity of glycosidase, accelerate discharge of uric acid through urine and block the path of conversion from fructose metabolism to uric acid; the celery seed flavone and the smilax glabra polysaccharide further play an anti-inflammatory role, the deposition risk of urate crystals at joints is reduced, and potential inflammatory response caused by hyperuricemia is relieved. Meanwhile, the resistant dextrin and the xylooligosaccharide serve as prebiotics, nutrients are provided for probiotics to support planting of the probiotics, the overall metabolic environment can be improved by adjusting intestinal flora balance, the pathological link of hyperuricemia is comprehensively covered, and the relieving effect is improved.

The invention belongs to the technical field of natural product extraction, and particularly relates to a research method for extracting polyphenol and flavonoid compounds in peony petals through an electrochemically-assisted eutectic solvent. The invention provides a research method for extracting polyphenols and flavonoids compounds in peony petals by using an electrochemically-assisted deep eutectic solvent, electrochemical wall breaking and DES regulation are combined for the first time by using a solvent design-electrochemical activation-targeted extraction method, phenol oxidation caused by traditional heating is avoided, and meanwhile, the extraction efficiency of the polyphenols and flavonoids compounds in peony petals is improved. The dissolution of target components is selectively enhanced through electrode reaction, the extraction efficiency of bioactive components in the peony petal powder is effectively improved, and the method has the advantages of greenness, high efficiency, short-time consumption reduction and the like, overcomes the defects in the prior art, and has a good application prospect.

The invention discloses a Lactobacillus buchneri strain with high yield of gamma-aminobutyric acid and application of the Lactobacillus buchneri strain in preparation of nutritional and healthy fruit and vegetable juice. The strain is Lactobacillus buchneri GM3, and is preserved in the Guangdong Microbial Culture Collection Center on January 9, 2025, and the preservation number of the strain is GDMCC No: 65737. The invention further discloses a preparation method of the Lactobacillus buchneri strain. The strain not only has the capacity of producing gamma-aminobutyric acid at high yield, but also has good acid resistance, cholate resistance and gastrointestinal fluid resistance, and is very suitable for fermentation production of fermented fruit and vegetable juice. The contents of gamma-aminobutyric acid and flavonoid substances in fruit and vegetable juice fermented by the strain are greatly increased, and the nutritional value of the fruit juice is remarkably increased; moreover, the contents of alkaloid substances and total sugar are remarkably reduced, so that the tea is healthier, and the flavor is better and more unique. The Lactobacillus buchneri GM3 is a safe lactic acid bacterium, and the Lactobacillus buchneri GM3 and the technology for producing fruit and vegetable juice through fermentation of the Lactobacillus buchneri GM3 have very good application value and market prospect.

The invention provides a prawn immunity-enhanced fermented functional feed and a preparation method thereof. Belongs to the field of animal feed. The feed comprises a basal feed and a feed additive, the feed additive comprises the following components: lactobacillus plantarum fermentation liquor, passion flower flavone and an immature bitter orange extract. Three functional components including the lactobacillus plantarum fermentation liquor, the passion flower flavone and the immature bitter orange extract are fused, a synergistic interaction system is constructed through a definite proportion, and the immunity of prawns is remarkably improved; the sources and the content of effective components of the immature bitter orange extract and the lactobacillus plantarum fermentation liquor are strictly limited, and the controllable product quality is ensured; the preparation process of the feed is simple, the key growth stage of shrimp culture is accurately positioned, and a comprehensive solution integrating probiotic regulation and control, plant active ingredient immune activation and process feasibility is provided for healthy culture of prawns.

The invention provides a method for extracting and separating a general flavone crude extract from paeonia lactiflora stems and leaves, which comprises the following steps: adding a choline chloride-malic acid eutectic solvent into paeonia lactiflora stem and leaf powder, soaking, carrying out ultrasonic treatment, carrying out suction filtration to remove solid impurities to obtain a paeonia lactiflora stem and leaf extracting solution, diluting with ultrapure water, carrying out electrodialysis treatment, and drying to obtain the general flavone crude extract. A solid-liquid mixture containing solid residues is obtained in the middle chamber, precipitates are reserved after centrifugation, and the total flavone crude extract is obtained after blow-drying. The invention also provides application of the extracted and separated total flavone crude extract in preparation of medicines, cosmetics or functional foods for antioxidation, anti-inflammation, anti-tumor, cardiovascular protection or / and immunoregulation. The method is high in separation speed, high in separation rate and environment-friendly, flavone loss can be reduced to the maximum extent, and the yield of the total flavone crude extract is 0.27%-0.39%.

The invention discloses a method for synergistically extracting flavonoid compounds in epimedium wushanense by combining a ternary eutectic solvent with in-situ ultrasound, which is characterized in that choline bitartrate-urea-glycerol (Chb: Ure: Gly) is used as the ternary eutectic solvent, and the flavonoid compounds in epimedium wushanense are synergistically extracted by the in-situ ultrasound. The method is high in extraction speed and good in repeatability, solvent consumption can be reduced, operation steps are simplified, and efficiency is improved.

The invention relates to the technical field of dried orange peel enzyme beverages, in particular to a dried orange peel enzyme beverage and a preparation method thereof. The dried orange peel enzyme beverage is prepared from the following raw materials in percentage by mass: 3-10% of dried orange peel, 0.5-2% of lemon juice, 5-15% of haws, 5-15% of pineapples, 3-10% of bitter gourds, 5-15% of red dates, 3-10% of longans, 1-5% of Chinese wolfberry fruits, 3-10% of sea-buckthorn and the balance of deionized water. According to the pericarpium citri reticulatae enzyme beverage and the preparation method thereof provided by the invention, through a specific fermentation process, the pericarpium citri reticulatae and a plurality of medicinal and edible food materials such as the hawthorn fruits, the Chinese wolfberry fruits and the bitter gourds are subjected to mixed fermentation, so that the original medicinal components of the pericarpium citri reticulatae are reserved, macromolecular substances are converted into micromolecular substances which are easily absorbed by a human body through the action of microorganisms, and the taste of the pericarpium citri reticulatae enzyme beverage is improved. The dried tangerine or orange peel beverage can be used as a raw material, such as lysine, arginine, histidine, oligosaccharide, flavonoids, polyphenols and the like, so that the innovative beverage not only enriches the variety of dried tangerine or orange peel products, but also provides a healthy and convenient health-preserving choice for modern people.

The invention belongs to the technical field of biosynthesis of plant secondary metabolites, and particularly relates to a key gene for biosynthesis of large-fruit hawthorn flavonoid compounds and a screening method and application of the key gene. Through combined analysis of metabolome and transcriptome, a key gene combination containing seven structural genes and three transcription factor genes is screened out; the expression of the genes is remarkably positively correlated with the accumulation of a target flavone metabolite [6]-gingerol, and the genes are core factors for regulating and controlling the synthesis of the flavonoid compounds of the big-fruit hawthorns through experimental verification. According to the invention, the key gene for regulating and controlling the synthesis of flavone substances such as [6]-gingerol in the big hawthorn fruit is systematically identified for the first time, and a target spot is provided for analyzing a quality formation mechanism from a molecular level; the gene can be used for molecular marker-assisted breeding so as to cultivate a new variety of large-fruit hawthorn with high flavone content, and also can provide gene resources and technical support for the development of functional food and health care products.

The invention discloses an extraction method of rose flavonoids, which comprises the following steps: S1, crushing selected dry Hetian rose buds, and storing for later use; s2, accurately weighing 1g of rose powder and putting the rose powder into a conical flask; s3, then, according to the material-liquid ratio of 1: 40, 40% ethanol is used as a solvent, and the materials are poured into a conical flask to be mixed; and S4, finally, soaking in a constant-temperature water area, extracting for 2 hours, and finally, taking supernate for later use. According to the invention, the solid-liquid ratio of 1: 40 ensures that the rose powder is fully infiltrated by an enough solvent (40% ethanol). Under the proportion, the ethanol can be in full contact with target components (such as flavonoid compounds and the like) in the rose powder. Each 1g of rose powder is surrounded by 40ml of solvent, so that target components have more opportunities to be dissolved out of powder particles to enter the solvent, and the extraction completeness can be improved compared with the condition that a feed liquid is relatively small.

The invention relates to a method and application of an LmbZIP11 gene and a homologous NbbZIP11 gene of the LmbZIP11 gene in regulating and controlling the content of chlorogenic acid and total flavonoids in plants. The method comprises the following steps: extracting RNA (Ribonucleic Acid) of leaves of lonicera macranthoides, designing a specific primer, cloning to obtain an LmbZIP11 gene, further constructing a recombinant overexpression vector and a VIGS (Vinyl Insulin Growth Sequence) silencing vector of the LmbZIP11 gene, and respectively transforming arabidopsis thaliana and nicotiana benthamiana; experiments show that the content of total flavonoids and chlorogenic acid in arabidopsis thaliana is remarkably increased through overexpression of the LmbZIP11 gene, and the content of metabolites in tobacco is remarkably reduced through silence of the NbbZIP11 gene homologous with the LmbZIP11 in Benen tobacco; the invention provides a new strategy for regulating the synthesis of plant secondary metabolites by using the LmbZIP11 gene, and can be used for improving the quality of medicinal plants.

The invention belongs to the technical field of medicine detection, and discloses a Raman spectrum-based traditional Chinese medicine decoction piece total flavone content detection method, which comprises: obtaining standard spectrum data of a standard flavone compound and characteristic spectrum data of a traditional Chinese medicine decoction piece sample; performing correlation degree evaluation according to the characteristic spectrum data and the standard spectrum data to obtain a flavone characteristic peak recognition matrix of each traditional Chinese medicine decoction piece sample; screening an effective characteristic wave band based on the flavone characteristic peak identification matrix; according to the spectral absorption intensity and the structure information of the effective characteristic wave band of each traditional Chinese medicine decoction piece sample, compiling a flavone quantitative characterization vector of the sample; detecting the content of total flavonoids in the traditional Chinese medicine decoction pieces on the basis of the flavone quantitative characterization vectors; the detection accuracy of the total flavone content of the traditional Chinese medicine decoction pieces is greatly improved.

The invention provides an extraction and detection method of a day lily active matter and application of the day lily active matter in anti-neuritis. Hemerocallis fulva contains various bioactive substances including flavone, polysaccharide and saponin, and the substances have potential application value in the fields of medicines and health care products. The invention provides a method for extracting the active components step by step, and rapid identification and detection are carried out by utilizing technologies such as fluorescence and ultraviolet-visible spectrophotometry. In addition, the invention also develops a detection method for evaluating the anti-neuritis effect of the active substances. Lipopolysaccharide (LPS) is used for stimulation to establish an inflammation model, day lily active substances are added, and the active substances are found to be capable of remarkably inhibiting generation and release of inflammatory factors and promoting growth and differentiation of neurons. Scientific basis is provided for developing new neuritis treatment methods, related drugs and the like.

The invention is applied to the technical field of health-care products, and discloses a sea-buckthorn soft capsule, which comprises a capsule shell and a content, the capsule shell is composed of gelatin, water, glycerin and an auxiliary material, the auxiliary material is a preservative or a plasticizer, the content is composed of one of seabuckthorn seed oil or fruit oil, seabuckthorn powder and an auxiliary material, the auxiliary material is one of a suspending aid and an antioxidant or a mixture of the suspending aid and the antioxidant, the seabuckthorn powder is rich in flavone, and the auxiliary material is a mixture of the suspending aid and the antioxidant. The soft capsule has the effects of lowering lipid, softening blood vessels and preventing vascular diseases. According to the hippophae rhamnoides soft capsule, a product capsule shell is prepared from gelatin, water and glycerin according to a specific proportion, it can be guaranteed that the capsule shell has proper hardness and elasticity and is convenient to process and store, hippophae rhamnoides seed (fruit) oil and hippophae rhamnoides powder in the content are matched according to a reasonable proportion, the hippophae rhamnoides powder is rich in flavone, and the hippophae rhamnoides powder and the hippophae rhamnoides seed (fruit) oil act the effects of lowering lipid, softening blood vessels and preventing vascular diseases can be better exerted.

The invention relates to the technical field of biological medicine, in particular to anti-acne hydrogel and a preparation method thereof. The anti-acne hydrogel is prepared from metal-polyphenol network nanoparticles and a hydrogel base material, the metal-polyphenol network nanoparticles comprise a first polyphenol compound, a second polyphenol compound and metal ions, the first polyphenol compound is a tannic acid compound, and the second polyphenol compound is a flavonoid compound; the hydrogel base material comprises a hydrophilic high-molecular polymer and a cationic polymer. The metal-polyphenol network nano-particles are creatively utilized, the anti-inflammatory and anti-oxidation activity of flavonoid compounds, the convergence and protein binding characteristic of tannin and the antibacterial activity of metal ions are integrated at the same time, and the vicious circle of acne can be intervened at the same time from multiple links of antibacterial, anti-inflammatory, anti-oxidation and keratinization adjustment; and the defect of single action target spot of the existing medicine is overcome.

This invention discloses a mechanochemical-assisted extraction method for total flavonoids from Hibiscus mutabilis flowers. Hibiscus mutabilis flowers and an auxiliary agent are added to a ball mill jar, zirconium beads are added as the grinding medium, and the jar is placed in a ball mill for co-grinding. After the reaction, the product is separated from the zirconium beads, and the ball-milled product is ultrasonically extracted with water to obtain a crude extract of total flavonoids from Hibiscus mutabilis flowers. This invention utilizes a mechanical ball milling reaction between the auxiliary agent and Hibiscus mutabilis flower powder. Under mechanical force, the particle size of the dried coarse Hibiscus mutabilis flower powder decreases, and the cell structure is destroyed, promoting the release of its active ingredients. Furthermore, by selectively adding solid reagents during co-grinding, utilizing the physicochemical properties of flavonoids, the flavonoids and auxiliary agent form salts under mechanical force, thereby increasing the extraction rate of flavonoids in water. Compared with existing extraction methods, this method has advantages such as environmental friendliness, good water solubility, high extraction rate, and simple operation, and has broad market application prospects.

The invention belongs to the technical field of active substance extraction, and discloses a method for extracting boxthorn leaf total flavonoids through an ultrasonic-assisted deep-eutectic solvent and application of the boxthorn leaf total flavonoids. Heating and mixing the hydrogen bond acceptor and the hydrogen bond donor, stirring to be transparent, and adding water to reduce viscosity to obtain the eutectic solvent; mixing the boxthorn leaf powder with a deep-eutectic solvent, performing ultrasonic extraction and centrifugation, and collecting supernate; adsorbing by using macroporous resin, washing and desorbing to obtain an eluent; and performing vacuum freeze drying to constant weight. According to the method disclosed by the invention, the eutectic solvent with low melting point and strong solubility is selected, the flavonoid compounds in the boxthorn leaves are green and efficiently extracted, and the total flavonoid content of the boxthorn leaves obtained by taking the eutectic solvent as an extraction solvent is 123.94 + / -1.04 mg / g and is far higher than the total flavonoid content of the boxthorn leaves obtained by traditional ethanol extraction by 64.60 + / -0.87 mg / g; the method is good in safety, short in time consumption and high in extraction rate.

The present invention relates to the technical field of functional food products. Disclosed are a rose enzyme liquid and rose enzyme beverage for promoting emotional health, and a preparation method therefor. Sour cherry flesh, double-petaled red roses, roselle, and Perillae folium are subjected to a colloid mill, and water is added for extraction and separation to obtain a concentrate. The concentrate is fermented with Lactiplantibacillus plantarum and Bifidobacterium longum to obtain a rose enzyme liquid, and the rose enzyme liquid is compounded with a saffron extract, a Mentha spicata extract, a bamboo leaf flavonoid, etc. to obtain a rose enzyme beverage. The rose, roselle, sour cherry and Perillae folium, which are both medicinal and edible, are selected as raw materials. The raw materials are fermented by means of using specific probiotic strains to effectively release active ingredients, which are then converted into small molecular substances that are easily absorbed by the human body and relieve emotional anxiety. Moreover, functional ingredients comprising the saffron extract, the Mentha spicata extract and the bamboo leaf flavonoid are compounded to effectively relieve stress, regulate daily negative emotions, and promote physical and mental relaxation, and enhance mental well-being. The sour and sweet taste satisfies consumers' pursuit for flavor, taste and efficacy.

The invention belongs to the field of microbial fermentation, and particularly discloses a method for fermenting astragalus membranaceus by lactobacillus plantarum. The method comprises the following steps: S1, crushing and sterilizing astragalus membranaceus; s2, inoculating lactobacillus plantarum LP-301; and S3, carrying out fermentation culture. After astragalus membranaceus is fermented by the lactobacillus plantarum LP-301, the contents of substances such as flavonoids, quinones and terpenes in a fermentation product are remarkably increased, so that the lactobacillus plantarum LP-301 can be used for preparing antioxidant products or anti-inflammatory products and has a relatively high application value.