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106 results about "Freckle" patented technology

Freckles are clusters of concentrated melaninized cells which are most easily visible on people with a fair complexion. Freckles do not have an increased number of the melanin-producing cells, or melanocytes, but instead have melanocytes that overproduce melanin granules (melanosomes) changing the coloration of the outer skin cells (keratinocytes). As such, freckles are different from lentigines and moles, which are caused by accumulation of melanocytes in a small area. Freckles can appear on all types of skin tones. Of the six Fitzpatrick skin types, they are most common on skin tone 1 and 2, which usually belong to North Europeans. However, it can be found in all ethnicities.

Whitening and freckle-removing composition, gel, preparation method therefor, and use thereof

Provided are a whitening and freckle-removing composition, a gel, a preparation method therefor, and a use thereof, relating to the technical field of skin-care products. The whitening and freckle-removing composition comprises tranexamic acid, nicotinamide, 4-butylresorcinol, licorice extract, 3-o-ethyl ascorbic acid, and glutathione. For the whitening composition, by inhibiting the activity of tyrosinase, blocking the transfer of melanin from melanocytes to keratinocytes, and inhibiting the formation and accumulation of melanin by means of multiple mechanisms including oxidation resistance, and by means of the synergistic action of all components, cosmetic benefits of whitening and freckle-removing are achieved. The whitening and freckle-removing gel has a simple preparation method, has a mild and non-sensitizing formula, is safe and non-irritating, and is suitable for large-scale production and application.
Owner:BEIJING CAS MICRONEEDLE TECH LTD +1

Medical soap for sterilizing, relieving itching and removing acne and manufacturing method thereof

InactiveCN107034048Aanti-allergySkin careSoap detergent compositionsSmelly feetAdditive ingredient
The invention discloses medical soap for sterilizing, relieving itching and removing acne and a manufacturing method thereof, belonging to the field of articles of everyday use. The medical soap is prepared from ingredient A, ingredient B and ingredient C, wherein the ingredient A is prepared from dandelions, folium isatidis, rabdosia rubescens and glabrous sarcandra herb; the ingredient B is prepared from radix angelicae, rhizoma typhonii, white poria, Chinese angelia root tai, radix pseudostellariae, raw milkvetch root, Chinese honeylocust fruit, red paeony root, prepared kusnezoff monkshood root, radices lithospermi, cortex dictamni, thunberg fritillary bulb, fiveleaf akebia fruit, white muscardine silkworms and solanum lyratum; the ingredient C is prepared from soap base, honey and bovine bone marrow oil. The medical soap disclosed by the invention is used for external washing or smearing after being wet by adding water in the morning and evening every day; after a person with smelly feet washes the feet, the medical soap is smeared in gaps between toes; and the medical soap is not suitable for use when the skin is damaged. The medical soap prepared by the invention is a black brown solid body, and has soap medicine odor; the medical soap can be used for nourishing the skin, is antiallergic, beautifies the features, removes acne, relieves itching, removes freckles, clearing heat and deterring sweat; the medical soap can beautify the features, whiten the skin, and remove the acne and the freckles when used for washing the face, and can deter the sweat, remove the smelly odor and treat dermatophytosis when used for washing the feet; and the medical soap has a control effect on the itching toxin which appears after mosquito bite, and has a moisturizing effect for the person having the dry skin.
Owner:崔新民

Use of a compound containing dendrobium officinale leaf extract in the preparation of a whitening and freckle-removing preparation

The application discloses application of a complex containing Dendrobium officinale leaf extract in preparation of a whitening and freckle-removing preparation, and the complex comprises the Dendrobium officinale leaf extract, a Rhizoma Polygonati extract and beta arbutin. After the components of the complex are mixed in a specific ratio and fully combined and synergized, the ability of inhibiting tyrosinase activity can be significantly improved by 300%, 175% and 87% respectively compared with the Dendrobium officinale leaf, the Rhizoma Polygonati and the beta arbutin, the melanin generation in zebra fish within 72 hours can be effectively inhibited, the melanin content can be obviously reduced, the melanin inhibition rate is increased by 394%, 532%, 24.14% and 37.39% respectively compared with the Dendrobium officinale leaf group, the Rhizoma Polygonati group, the beta arbutin group and the Dendrobium officinale leaf-Rhizoma Polygonati group, the Dendrobium officinale leaf-Rhizoma Polygonati complex can obviously improve the melanin inhibition rate in zebra fish, the combination of the two and the beta arbutin can make the melanin inhibition rate reach 98.70%, and the whitening and freckle-removing effect of skin can be greatly enhanced.
Owner:ZHEJIANG UNIV OF TECH

Preparation method and equipment of freckle-removing mask

The invention discloses a freckle-removing mask preparation method and equipment, and relates to the technical field of beauty and skincare, the freckle-removing mask preparation method comprises the following steps: S1, selecting and purchasing: selecting and purchasing high-quality formula raw materials; s2, inspection: inspecting the purchased raw materials; s3, pretreatment: washing part of the Chinese herbal medicine raw materials with clear water, and drying the Chinese herbal medicine raw materials; s4, pre-processing: crushing and grinding the prepared raw materials, and screening and filtering to remove impurities; the facial mask is prepared from ligusticum, radix angelicae, radix asparagi, astragalus membranaceus, bighead atractylodes rhizome, silkworm larva, bletilla striata, radix paeoniae alba, poria cocos, salvia miltiorrhiza, ampelopsis japonica, tribulus terrestris, pseudo-ginseng, rose, ginseng, honeysuckle, pearl and other blood-activating and repairing components, so that the effect of eliminating laser spots and heavy metal residual spots is improved, and meanwhile, the whitening degree and the skin glossiness are improved; the ductility, the moistening property and the permeability are improved, the stickiness and the greasiness are reduced, the moisturizing and water locking durability is improved through moisturizing factors of various components, and the spot fading effect is improved.
Owner:GUANGXI HUIHUATANG AGRICULTURAL CO LTD

Whitening and spot-fading composition and application thereof

PendingCN121081310ACosmetic preparationsToilet preparationsBiotechnologyGlycyrrhiza glabra Root
The invention discloses a whitening and spot-fading composition and application thereof, and belongs to the technical field of cosmetics. The whitening and spot-fading composition is prepared from the following components in percentage by mass: 0.1 to 5.0 percent of nicotinamide, 0.0001 to 3.0 percent of tranexamic acid, 0.0001 to 1.0 percent of glycyrrhiza glabra root extract, 0.0001 to 0.4 percent of phenethyl resorcinol, 0.0001 to 2.0 percent of ascorbyl tetraisopalmitate, 0 to 1.0 percent (not including 0) of radix gentianae extract, 0.15 to 4.0 percent of emulsifier, 0.1 to 2.5 percent of antioxidant and the balance of water. By matching with various whitening active ingredients, the comprehensive whitening, brightening and skin improving effects are realized in the aspects of inhibiting melanin generation, blocking melanin transfer, accelerating melanin metabolism and the like; the combination of the specific emulsifier and the thickener can effectively improve the component stability of the composition. The composition is mild in performance, free of irritation to skin and good in market value.
Owner:广东博然堂生物科技有限公司

Use of steroidal compounds

The present application provides a kind of application of the steroid compound in preparation prevention or treatment skin pigmentation related condition or anti-aging related product, the steroid compound is as shown in formula I, and has treatment, lightening and / or alleviating effect on senile plaques, freckles, chloasma and the like caused by pigmentation on the skin of mammal.(I).
Owner:OCUSUN OPHTHALMIC PHARM (GUANGZHOU) CO LTD

Maqui berry extracts for treatment of skin diseases

The present invention relates generally to maqui berry for use in the treatment or prevention of skin diseases, wherein maqui berry may be the primary natural active ingredient. Particular embodiments as disclosed herein find application in, inter alia, the prophylaxis and the treatment of skin diseases, in particular, dermatitis, atopic dermatitis (neurodermatitis), dermatitis solaris, eczema, hand eczema, lichen planus, lupus erythematosus, psoriasis, urticaria, itching, scabies, age spot, freckles and dry / atopic skin of humans. In particular, the present invention relates to the use of maqui berry extract in the manufacture of a medicament or dietary supplement for use in treating or preventing said skin diseases or defects.
Owner:ANKLAM EXTRAKT GMBH

Mud mask containing corn stigma extract and having effects of repairing, resisting wrinkles and removing freckles and preparation method of mud mask

The invention provides a corn stigma extract-containing mask mud with repairing, anti-wrinkle and freckle-removing effects and a preparation method thereof, and relates to the technical field of cosmetics. The mask mud is prepared from the following raw materials: corn stigma extract, guava fruit extract, white willow bark extract, tamarix chinensis flower extract, sulfonic acid hydroxypropyl ester lauryl glucoside cross-linked polymer sodium and auxiliary materials. The corn stigma extract is taken as a main raw material, and the three natural extracts, namely the guava fruit extract, the white willow bark extract and the tamarix chinensis flower extract, are compounded according to a specific proportion, so that multiple effects of resisting wrinkles, removing acnes, whitening, resisting allergy, repairing, removing freckles, tightening, moisturizing, soothing and the like are realized at the same time, and the effect of the corn stigma extract is remarkably improved; sulfonic acid hydroxypropyl ester lauryl glucoside cross-linked polymer sodium is used as a surfactant, so that the lotion is milder and more moisturizing, no preservative is added, and damages such as skin irritation, allergy, red and swollen skin, cuticle damage and dry skin are reduced.
Owner:YUNONGYUAN FOOD CO LTD

A composition with whitening and freckle-removing effects, and a preparation method and application thereof

PendingCN122321062ABiotechnologyMetabolic waste
This invention discloses a composition with whitening and freckle-removing effects, its preparation method, and its application, belonging to the field of composition technology. The composition provided by this invention reduces the body's oxidative stress level, providing a suitable internal microenvironment for the efficacy of various drugs and the repair of damage; it provides a sufficient, diverse, and easily absorbed material basis for skin damage repair; it significantly improves the whitening and freckle-removing effect by increasing the activity, purity, and content of the components that directly have whitening and freckle-removing effects; and it promotes the excretion of metabolic waste by improving gastrointestinal health. It is extremely safe, requires minimal equipment, and is environmentally friendly, making it suitable for daily skin repair and whitening / freckle-removing edible use.
Owner:恢春丹生物科技(海南)有限公司

Freckle-removing and whitening mask and preparation method thereof

The invention discloses a freckle-removing and whitening mask which is prepared from the following raw materials: chrysanthemum, pearl, radix angelicae, almond, poria cocos, rhizoma atractylodis macrocephalae, peach kernel, ginseng, mung bean, bletilla striata, cortex moutan, rhodiola rosea, silkworm larva, Chinese yam, honeysuckle and the like. The facial mask is a pure traditional Chinese medicine facial mask, has remarkable curative effects on whitening, removing freckles, removing acnes and minimizing pores, and can effectively reduce facial skin damage, effectively inhibit growth of facial germs, promote vigor of subcutaneous capillaries of the damaged face, improve metabolism of the skin and enable the facial skin to reappear in a compact and refined state. In addition, the facial mask can enhance the ability of facial skin to resist invasion and stimulation of external germs, form a natural protective barrier for the facial skin, well repair, moisten and care the facial skin, and keep the facial skin comfortable, beautiful and healthy for a long time. Pure traditional Chinese medicine raw materials are selected, chemical components are not added, and harm to facial skin and the body is avoided.
Owner:董西源

Preparation method and equipment of skin care product for whitening, removing freckles, smoothing skin and preserving moisture

The invention relates to the technical field of skin care product preparation, and discloses a skin care product preparation method and equipment capable of whitening skin, removing freckles, smoothing skin and preserving moisture, and the skin care product is prepared from the following raw materials in percentage: 30% of tea leaf extract, 15% of oat extract, 15% of rose extract, 20% of centella asiatica extract, 5% of vitamin E, 10% of pearl powder and 5% of chitosan. The skin care product capable of whitening, removing freckles, smoothing skin and preserving moisture can be prepared, in the preparation process, the liquid level of mixed liquid can be moved upwards during stirring, raw materials left on plastic cloth due to liquid level recovery after stirring is stopped are flapped and shaken off into the mixed liquid, full utilization of the raw materials is guaranteed, the preparation effect is improved, and the skin care product can be used for whitening, removing freckles, smoothing skin and preserving moisture during flapping and shaken off. And the flapped raw materials can be blown downwards, so that the raw materials are prevented from flying onto the stirring assembly, and the raw materials are ensured to fully return to the mixed liquid.
Owner:GUANGZHOU KONI INT BIOTECHNOLOGY CO LTD

Anti-aging repair essence containing active ingredients of chlorella vulgaris and preparation method thereof

PendingCN122643203ACholesterolSkin repair
The present application relates to a kind of anti-aging repair essence containing chlorella active ingredient and preparation method thereof.The component of the anti-aging repair essence containing chlorella active ingredient includes chlorella active ingredient, barrier repair agent, humectant, antioxidant, thickening agent and deionized water;The barrier repair agent includes ceramide, cholesterol and plant sphingosine alcohol.The essence provided by the present application takes chlorella active ingredient as main active ingredient, is supplemented with barrier repair agent, humectant, antioxidant and other components, is synergized by promoting cell regeneration, antioxidant protection, promoting collagen synthesis, repairing skin barrier and other multi-target points, realizes the multiple effects of skin repair, anti-aging, whitening and freckle removal, and safety is good, is suitable for long-term use of various skin qualities.
Owner:YAZHI YOUPIN (GUANGDONG) INTELLIGENT BIOTECHNOLOGY CO LTD +1

Laser therapy machine (YL900-2024)

1. Name of the product subject to this design: Laser Therapy Machine (YL900-2024). 2. Application of this design: for use in the medical aesthetics industry for skin rejuvenation, freckle removal, pigmentation reduction, and treatment of rosacea. 3. The key design feature of this product is its shape. 4. The image or photograph that best illustrates the design's key points: 3D view 1. 5. The bottom surface of this product is a part that is not easily seen or cannot be seen during use, so the bottom view is omitted.
Owner:SHANDONG JIEMEI MEDICAL TECH

Highly absorbable whitening and freckle-removing skin care product and preparation process thereof

The application discloses a high-efficiency absorption whitening and freckle-removing skin care product and a preparation process thereof, and belongs to the technical field of cosmetics. The high-efficiency absorption whitening and freckle-removing skin care product contains the following components in terms of weight parts: 0.1-5 parts of a whitening compound (I), 5-10 parts of cocoyl glucoside, 0.5-1 part of menthol, 5-10 parts of phospholipid, 0.5-1 part of EDTA, 0.1-1 part of hyaluronic acid and 150-200 parts of deionized water. The whitening and freckle-removing skin care product has good antioxidant and tyrosinase enzyme activity inhibiting effects, and can realize the effects of whitening and freckle removal.
Owner:GUANGDONG CONFULAY BIOTECHNOLOGY CO LTD

Essential oil composition having whitening and spot-fading effects and method for preparing the same

PendingCN122097201ACosmetic preparationsFungiBiotechnologySandalwood oil
The present application relates to a kind of essential oil composition with whitening and freckle lightening effect and its preparation method, belong to the technical field of cosmetics.The essential oil composition with whitening and freckle lightening effect provided by the present application includes Italian helichrysum oil, rice germ oil, sandalwood oil, white spring chamomile flower oil, rust red rose seed oil and pink passion fruit seed oil treated by specific fermentation process, all ingredients are derived from natural plants, no chemical synthetic substance is added, irritability is low, safety is high, has good whitening, freckle lightening effect, also has anti-inflammatory, antioxidant and barrier repair effect, suitable for various skin.
Owner:ZHUHAI ONWARD BIOCHEM TECH

A whitening and anti-aging composition for skin care and application thereof, and an essence oil and a preparation method thereof

The present application relates to the field of skin care products, and discloses a whitening and anti-aging composition for skin care products and application thereof, and an essence oil and a preparation method thereof. The whitening and anti-aging composition for skin care products contains an active substance combination and a compound essential oil and plant oil combination; the active substance combination contains glabridin, 4-butyl resorcinol, undecylenoyl phenylalanine, natural bisabalol, ascorbic acid tetraisopalmitate and teprenone; the compound essential oil and plant oil combination contains Damascus rose essential oil, magnolia essential oil, frankincense essential oil, Roman chamomile essential oil, carrot seed essential oil, passion fruit seed oil, red wolfberry seed oil, rose fruit oil and sea buckthorn fruit oil. The skin care product prepared from the whitening and anti-aging composition has a more moderate and efficient transdermal absorption rate, and has excellent anti-photoaging effect and whitening and freckle-removing effect.
Owner:CHANGSHA DAISY BIOTECHNOLOGY CO LTD

Packaging box (autumn He Lai people blemish whitening set)

1. The name of the design product: packaging box (autumn He Lai people white and freckle beauty set). 2. The use of the design product: used for the packaging of freckle-removing and whitening skin care products. 3. The design points of the design product: the combination of shape and pattern. 4. The picture or photo that best indicates the design points: perspective drawing.
Owner:YINGDIAN ENTERPRISE MANAGEMENT (NANJING) CO LTD

Handle of intense pulsed light therapeutic instrument (QMC-C-H03)

ActiveCN309555752SFacial skinBiochemistry
1. The name of the design product: Intense pulsed light therapy instrument handle (QMC-C-H03). 2. The use of the design product: The design product is used for facial skin tender, wrinkle removal, hair removal, and freckle removal. 3. The design points of the design product: The shape of the product. 4. The picture or photo that best indicates the design points: perspective view.
Owner:MEDUSA (CHONGQING) MEDICAL DEVICES CO LTD

Handle of intense pulsed light therapeutic instrument (QMC-C-H04)

ActiveCN309561643SFacial skinBiochemistry
1. The name of the design product: Intense pulsed light therapy instrument handle (QMC-C-H04). 2. The use of the design product: The design product is used for facial skin tender, wrinkle removal, hair removal, and freckle removal. 3. The design points of the design product: The shape of the product. 4. The picture or photo that best indicates the design points: perspective view.
Owner:MEDUSA (CHONGQING) MEDICAL DEVICES CO LTD

Whitening facial cleanser and preparation method thereof

PendingCN121313507ACosmetic preparationsToilet preparationsOLEAMIDOPROPYL BETAINESodium Lauryl Sarcosinate
The invention discloses a whitening facial cleanser and a preparation method thereof, and relates to the field of skin care products. The whitening facial cleanser is prepared from 35 to 42 weight percent of a cleaning agent, 1 to 2 weight percent of a whitening and freckle-removing agent, 0.8 to 1.2 weight percent of a skin conditioner, 4 to 8 weight percent of an emollient, 4 to 6 weight percent of a humectant, 0.3 to 0.5 weight percent of a preservative, 0.05 to 0.1 weight percent of a chelating agent, 4 to 4.5 weight percent of a thickening agent, 0.2 to 0.5 weight percent of an aromatic, 0.8 to 1.0 weight percent of a pH regulator and the balance of a solvent. The cleaning agent is prepared from sodium lauroyl isethionate, sodium cocoyl aminopropionate, cocamidopropyl betaine and sodium lauroyl sarcosinate according to the weight ratio of (3.5 to 4.5) to 1 to 1 to 1; the preservative comprises DMDM hydantoin and methylparaben in a weight ratio of (3-4): 1. The whitening facial cleanser provided by the invention has both cleaning power and mildness, and also has a whitening effect.
Owner:ZHAOQING QIAOQIAO DAILY CHEM CO LTD

A facial mask with whitening, moisturizing and freckle-removing functions and its preparation method

This application relates to the field of health product technology, specifically disclosing a facial mask with whitening, moisturizing, and freckle-removing functions and its preparation method. This facial mask with whitening, moisturizing, and freckle-removing functions comprises the following components in parts by weight: 15-25 parts of peach blossom Bletilla striata polysaccharide complex, 5-12 parts of silkworm pupae enzymatically hydrolyzed oligopeptides, 10-20 parts of biomimetic membrane-modified starch microspheres, 35-50 parts of winter melon juice lactic acid bacteria fermentation supernatant, and 1-3 parts of antioxidant complex. This application uses peach blossom Bletilla striata polysaccharide complex, silkworm pupae enzymatically hydrolyzed oligopeptides, biomimetic membrane-modified starch microspheres, winter melon juice lactic acid bacteria fermentation supernatant, and antioxidant complex in a compounded manner according to their weight proportions. The complex and oligopeptides exist in a molecular-level dispersion state, the microspheres act as carriers to uniformly carry the active components, and the antioxidant complex maintains the stability of the system. Therefore, it achieves the effects of highly dispersed active ingredients, sufficient contact with the skin during application, and improved retention rate of active substances after washing.
Owner:BENMIN (HAINAN) INVESTMENT CO LTD

Makeup applicator comprising protrusions

Devices and methods for applying makeup to skin are generally provided. In some embodiments, the devices and methods disclosed herein may be used to apply makeup to skin in a pattern that mimics a natural arrangement of freckles or other pigment irregularities of the skin. In some embodiments, the appearance of pigment irregularities such as those that mimic naturally occurring arrangements of freckles may be desirable, based on the aesthetic preferences of a user. Advantageously, the devices and methods disclosed herein may allow for the application of makeup to the skin in a pattern that looks similar to (e.g., mimics) naturally occurring arrangements of freckles. Without wishing to be bound by a particular theory, it is believed that several features of the disclosed devices (e.g., variations in the height and / or spacing of protrusions configured to mimic an arrangement of freckles, as described in greater detail below) may accurately mimic the variations in size and spacing found in naturally occurring arrangements of freckles. The methods as described herein may also allow for a user to control the level of pigmentation, shape, and / or spacing of deposits of makeup transferred to the skin, which is believed to also allow for the accurate mimicking of variations of size, shape, and pigmentation levels in naturally occurring arrangements of freckles.
Owner:LOVE YOUR FRECKLES LLC

Aesthetic skin care

Device: The invention aims to treat skin imperfections (spots, angiomas, freckles, marks, spots, discolorations, stretch marks, scars, etc.), to erase them, and to diminish their appearance. More and more people are experiencing problems with skin imperfections (spots, angiomas, freckles, marks, spots, discolorations, stretch marks, scars, etc.), and are particularly sensitive to what they consider a problem. This constitutes a real societal phenomenon. Many people are distressed by these visual aspects of their skin. It is therefore necessary to make these features invisible or less visible. The proposed technical solution is to use colored inks to create a skin tone match and to tattoo the area to be treated with this ink. [Fig. 1] A specific needle [Fig. 2] can be used for this procedure.
Owner:CRESSONNIER RODOLPHE

High-concentration hydrogen peroxide emulsion for treating senile plaques and application of high-concentration hydrogen peroxide emulsion

The invention provides a high-concentration hydrogen peroxide emulsion for treating senile plaques and application thereof, and in the high-concentration hydrogen peroxide emulsion, hydrogen peroxide is used as an active component, can oxidize and decompose melanin in skin, and has a freckle removing effect; the hydrogenated polydecene is used as an emollient, so that the skin can be moistened and the texture of the skin is improved; hydrogenated castor oil (PEG-40) is used as an emulsifier, so that an emulsion system is stable; the bisabolol has anti-inflammatory and soothing effects, and can relieve the irritation of hydrogen peroxide to the skin; citric acid can adjust the pH value of the emulsion, so that the emulsion is more suitable for the physiological environment of skin; sodium hyaluronate has a moisturizing effect and can enhance the barrier function of skin. All the components have a synergistic effect, so that the emulsion has a good senile plaque treatment effect, and meanwhile, irritation to skin is reduced.
Owner:胡中柱

Undecylenoyl phenylalanine nicotinamide whitening and freckle lightening ternary co-assembly, and preparation method and application thereof

PendingCN122624311APersonal careCyclodextrin
The application belongs to the technical field of biological medicine, cosmetics, personal care and health, and discloses a undecylenoyl phenylalanine nicotinamide whitening and freckle lightening ternary co-assembly body as well as a preparation method and application thereof. The method comprises the following steps: first, preparing an alcohol phase pre-solution of undecylenoyl phenylalanine, dissolving nicotinamide and cyclodextrin in an alcohol-water mixed solution to prepare a co-solution, mixing the two, and then performing high-shear homogenization and spray drying to obtain the ternary co-assembly body. The three components form a co-assembly system through non-covalent forces such as hydrogen bonds, van der Waals forces and hydrophobic interactions, can inhibit the crystallization of active substances, and improve the synergistic dispersion stability of whitening components. The water phase dispersibility, permeability and formula compatibility of the ternary co-assembly body are improved. At the same time, the co-assembly body is beneficial to the synergistic delivery of undecylenoyl phenylalanine and nicotinamide, perfects the whitening action paths such as melanin generation signal regulation, melanin transport intervention, skin color improvement and auxiliary improvement of cell energy metabolism, and can be applied as a cosmetic active raw material in whitening and skin care products such as essences, emulsions, masks and creams.
Owner:HUIBO BIOTECHNOLOGY (GUANGZHOU) CO LTD

Packaging box (whitening freckle-removing mask)

1. The name of the design product: packaging box (whitening and freckle-removing mask). 2. The use of the design product: for product packaging. 3. The design points of the design product: in shape. 4. The picture or photo best indicating the design points: perspective view 1.
Owner:GUANGZHOU YANHOU COSMETICS CO LTD

Freckle Removal Cream (with Yellow Skin Essential Oil)

1. Name of the product in this design: Freckle Removal Cream Pen (Yellow Skin Essential Oil). 2. Purpose of this design: A freckle-removing ointment pen for removing freckles. 3. The key design feature of this product is its shape. 4. The image or photograph that best illustrates the design's key points: 3D view 1.
Owner:GUANGZHOU CITY POLYTECHNIC

Tranexamic acid-tyrosinase inhibitor hybrid conjugate as well as preparation method and application thereof

The invention discloses a tranexamic acid-tyrosinase inhibitor hybrid conjugate as well as a preparation method and application thereof, belongs to the technical field of cosmetics and biological medicines, and particularly relates to a tranexamic acid-tyrosinase inhibitor hybrid conjugate shown in a formula (I) and a skin composition taking the compound as an active component. According to the hybrid conjugate, tranexamic acid and a tyrosinase inhibitor are integrated into a single-structure molecule through an ester bond, so that the transdermal efficiency can be improved and the transdermal dynamic difference limitation of a traditional compound preparation can be broken through by adjusting the hydrophilic-hydrophobic balance of the compound; and plasmin activity can be inhibited through cooperation of tranexamic acid, so that melanin generation signal transmission capability and tyrosinase inhibition capability of tyrosinase inhibitor specificity are reduced, and efficient and mild multi-channel whitening and spot fading are realized. As a whitening active matter, the tranexamic acid-tyrosinase inhibitor hybrid conjugate disclosed by the invention has a great application prospect in the aspects of whitening and freckle removing effects.
Owner:SHENZHEN TIDAL INTERFACE BIOTECHNOLOGY CO LTD

Freckle-removing mask for transdermal drug delivery of soluble microneedle array and preparation method of freckle-removing mask

The invention discloses a soluble microneedle array transdermal drug delivery freckle-removing mask and a preparation method of the soluble microneedle array transdermal drug delivery freckle-removing mask. The mask comprises a backing layer and a soluble micro-needle array arranged on the backing layer, the micro-needle array is composed of a needle tip and a base, and the needle tip comprises a freckle-removing active component, a nano-carrier material, a micro-needle matrix material and a stabilizer. The freckle-removing active components comprise tranexamic acid, sodium ascorbyl phosphate, Maojian green tea extract, licoflavone and nicotinamide; the nano carrier material is selected from hydroxyl cyclodextrin, chitosan nanoparticles and alginic acid-chitosan nanoparticles; the microneedle matrix material comprises hyaluronic acid, polyvinylpyrrolidone and polyvinyl alcohol. Through combination of a nano-carrier technology and a micro-needle system, the drug loading capacity, stability and transdermal efficiency of freckle-removing active ingredients are remarkably improved, and the freckle-removing micro-needle has the advantages of being good in freckle-removing effect, painless, noninvasive, convenient to use and the like, and is suitable for prevention and treatment of chloasma, freckles, hyperpigmentation after inflammation and other pigmented skin diseases.
Owner:JINHUA JINGDI MEDICAL SUPPLIES CO LTD

Markers for skin metabolic phenotyping and uses thereof

PendingCN122307078AMetaboliteMetabolomics data
This invention belongs to the field of biodetection technology, specifically disclosing a novel skin typing method, biomarkers based on skin surface metabolomics typing, and their applications. Based on population-level skin surface metabolite measurement data and through multi-dimensional scientific analysis, this application ultimately discovered that the skin samples of the subjects formed two distinct clusters. This demonstrates that differences in metabolomics clusters based on skin typing objectively exist. Furthermore, the two distinct clusters based on the aforementioned skin surface metabolomics data are named "Metabolic Type 1" or "Metabolic Type 2." Simultaneously, these two typing methods also exhibit differences in various skin condition indicators (e.g., sebum levels, actual age, wrinkles, freckles, etc.). By using the typing method provided in this application to study skin surface metabolomics substances, one or more metabolites can be used as biomarkers to identify the specific skin typing level and guide adjustments to the desired skin condition. This application overcomes the limitations of existing methods that define skin typing solely based on dry, oily, etc., providing more comprehensive guidance for practice.
Owner:GUANGDONG HONG KONG MACAO GREATER BAY AREA PRECISION MEDICINE RESEARCH INSTITUTE (GUANGZHOU)