38 results about "Gentiana" patented technology

The invention provides a lipid-lowering traditional Chinese medicine composition and extract as well as a preparation method and application thereof, and belongs to the technical field of traditional Chinese medicines. The lipid-lowering traditional Chinese medicine composition is prepared from the following raw materials: rhizoma cyperi and radix gentianae. The invention further provides an extract of the lipid-lowering traditional Chinese medicine composition. The extract is obtained by mixing rhizoma cyperi and radix gentianae and then co-extracting. The composition or the extract can be used for preparing medicines for preventing and / or treating hyperlipemia, and can be used for improving lipid metabolism disorder of liver cells and reducing the content of triglyceride and total cholesterol in the liver cells.

The invention discloses a roegneria ciliata PmRc1 gene, a protein coded by the roegneria ciliata PmRc1 gene and application of the roegneria ciliata The sequence of the powdery mildew resistance gene PmRc1 is derived from a small fragment translocation line TT-7 created by tetraploid roegneria ciliata and common wheat, the nucleotide sequence of the powdery mildew resistance gene PmRc1 is SEQ ID NO.1, and the amino acid sequence of the powdery mildew resistance gene PmRc1 is SEQ ID NO.2. The roegneria ciliata PmRc1 gene and the recombinant expression vector are applied to cultivation of wheat varieties with powdery mildew resistance. According to the candidate gene of the powdery mildew resistance gene PmRc1 derived from roegneria ciliata, the susceptibility can be enhanced by silencing the gene in a disease-resistant material, and the powdery mildew resistance can be improved by overexpressing the gene. The invention has important significance on wheat powdery mildew resistance breeding.

The invention belongs to the technical field of external traditional Chinese medicine ointment, and particularly relates to traditional Chinese medicine ointment for treating arthralgia. The traditional Chinese medicine composition specifically comprises the following raw materials: ground beetles, saline scorpions, centipedes, leeches, earthworms, silkworm larva, cantharides, rhizoma drynariae, shelled semen strychni, corydalis amabilis, peach kernels, saffron crocus, notopterygium roots, gentiana macrophylla, trogopterus dung, buttercup, cottonrose hibiscus leaves, borneol and musk. According to the invention, synergy of insect drugs and botanical drugs for dispelling wind and promoting blood circulation is taken as a core, and the composition is adapted to complex syndromes of arthralgia. The problems of component inactivation, degradation and insufficient extraction are avoided by adopting split-phase extraction; controlled-release microcapsules are separately arranged for high-risk groups such as cantharides to reduce stimulation and slow release, borneol and musk are included to increase stability, and infiltration promotion and slow release are complementary; an oil-water system is constructed by the cream matrix, and the cream has sealing performance, spreadability and residence performance and is suitable for external massage.

The application provides a device for soil removal and root separation of gentiana root system and a working method thereof. The device comprises a feeding port, a sliding hammer impact mechanism, an eccentric vibrating conveyor belt, an extrusion roller pair, a main motor, a turnover plate, a flexible rubber belt beating mechanism, a rack, a concave-convex roller system combing mechanism and a collecting tank. The eccentric vibrating conveyor belt comprises an upper eccentric vibrating conveyor belt and a lower eccentric vibrating conveyor belt. The extrusion roller pair comprises an inclined extrusion roller pair and a horizontal extrusion roller pair connected with each other. The sliding hammer impact mechanism, the flexible rubber belt beating mechanism and the eccentric vibrating conveyor belt realize the separation of the root system and the soil through knocking, beating and vibrating. The extrusion roller pair and the concave-convex roller system combing mechanism damage the net structure formed by the entanglement of the root systems of different plants through extrusion and pulling, so that the root separation effect of different plants is realized.

The invention relates to the technical field of oral care, and provides Chinese herbal medicine plant toothpaste and a preparation method thereof.The toothpaste is composed of wild mint, paris polyphylla roots, pseudo-ginseng roots, dandelion, radix paeoniae alba, moutan bark, honeysuckle, wild chrysanthemum flowers, gentiana rigescens, verbena, herba lycopi, gypsum, calculus bovis and matrix auxiliary materials, and core raw materials are Yunnan genuine medicinal materials. The preparation process combining segmented extraction and nitrogen protection superfine grinding is adopted, effective components of Chinese herbal medicines are fully released, all the components have a synergistic effect, and the toothpaste has the comprehensive effects of preventing oral ulcer, whitening, removing halitosis, strengthening teeth, diminishing inflammation, killing bacteria, reducing stomach fire, stopping bleeding and strengthening the oral cavity; particularly, the effects of inhibiting oral pathogenic bacteria, repairing gingival injury and removing dental plaque are obvious. The product is controllable in process, high in stability, mild and non-irritant, can comprehensively solve various potential oral problems, and meets the high-quality oral care requirements of consumers.

The application provides a kind of external use traditional Chinese medicine composition for treating gouty arthritis and its preparation method and application, it is related to the technical field of traditional Chinese medicine.The external use traditional Chinese medicine composition comprises, by mass fraction, radix tripterygii wilfordii 10-35 parts, zanthoxylum 5-25 parts, phellodendron 15-35 parts, herba lycii 5-25 parts, alisma 10-35 parts, panax notoginseng 40-90 parts, gentiana 40-90 parts, notopterygium 40-90 parts and dried ginger 40-90 parts.Through the triple recombination of radix tripterygii wilfordii and zanthoxylum, phellodendron and herba lycii, gentiana and notopterygium, the external use traditional Chinese medicine composition obtained under a specific ratio has few medicinal ingredients, good effect, easy storage and convenient carrying, and can effectively treat gouty arthritis.

The invention discloses an external nursing cream containing white muscardine silkworm and gentiana macrophylla and a preparation method thereof, the nursing cream takes white muscardine silkworm and gentiana macrophylla as main raw materials, the main raw materials are extracted by ethanol with the concentration of 20-99%, and the ethanol can be edible wine, health care medicinal liquor or medical ethanol; and the finished product is mild for external use after being blended by a matrix, and the irritation is controllable. Auxiliary materials such as artificial musk, ground beeltle, mirabilite, myrrh and angelica sinensis can be selectively added, and the ointment is prepared by extracting, concentrating and adding an external matrix. The invention has the advantages of simple and mild formula, flexible and simple process, easily available raw materials and wide application range, and is suitable for daily external skin care.

The invention discloses a traditional Chinese medicine composition for treating rhinitis and a preparation method and application thereof, and belongs to the technical field of traditional Chinese medicine, the traditional Chinese medicine composition comprises a medicine for external application and a medicine for oral administration, the medicine for external application comprises the following components in parts by weight: 1-2 parts of dried raw centipede, 1-5 parts of river worm, 1-2 parts of prepared kusnezoff monkshood root, 1-10 parts of dried raw scorpion and 1-2 parts of prepared monkshood; the medicine for oral administration comprises the following components in parts by weight: 1-20 parts of felwort, 1-20 parts of roasted rhizoma atractylodis macrocephalae, 1-10 parts of fructus forsythiae, 1-3 parts of mint, 1-5 parts of chrysanthemum morifolium ramat, 1-10 parts of honeysuckle, 1-3 parts of liquorice, 1-30 parts of pollen and 1-10 parts of towel gourd vine. The traditional Chinese medicine composition provided by the invention can effectively relieve rhinitis symptoms and improve the living quality of patients in a manner of combining external application and oral administration, and is low in recurrence rate and free of obvious side effects.

The invention relates to a mild moisturizing and soothing composition and application thereof.The composition is prepared from, by weight, 5-10 parts of lactobacillus / algae extract fermentation products, 2-5 parts of capparis spinosa fruit extract, 3-5 parts of olive fruit oil and 10-15 parts of schisandra chinensis fruit extract-radix gentianae extract, and the four components synergistically improve the moisturizing and soothing effect of the composition. The fructus schisandrae chinensis extract-radix gentianae extract disclosed by the invention is subjected to biotransformation and synergistic metabolism through compound zymophyte, so that the utilization rate of active ingredients in the fructus schisandrae chinensis extract and the radix gentianae extract is remarkably increased, the efficacy range of the fructus schisandrae chinensis extract and the radix gentianae extract is expanded, and the fructus schisandrae chinensis extract-radix gentianae extract can achieve the effects of regulating inflammatory response, reinforcing skin barrier and whitening skin. The skin barrier problem of eczema is fundamentally solved, skin scratching, stabbing and discomfort are reduced, eczema relapse is reduced, the dry peeling problem caused by indoor and outdoor temperature difference and dry areas is solved, water loss is reduced, oxidative damage is resisted, and the like.

The present invention relates to a quality control method for Jingutongxiao pills, belonging to the technical field of traditional Chinese medicine. The quality control method is based on the existing quality standards, by adding the thin layer identification of licorice, improving the thin layer identification of cyperus rotundus, cinnamon twig, white peony root, cyperus rotundus and gentiana, and using HPLC to simultaneously determine cryptotanshinone, tanshinone I and tanshinone II A The content of the product was optimized and the chromatographic conditions were optimized, thus achieving the technical goal of better controlling the product quality.

The application discloses a traditional Chinese medicine oral liquid for preventing and treating pig viral diarrhea disease and a preparation method and application thereof. The traditional Chinese medicine oral liquid comprises the following active components: honeysuckle, radix scutellariae, capillaris, viticis trifolia, gardenia, gentiana, salvia miltiorrhiza, dried tangerine or orange peel, radix notoginseng, ligustrum lucidum and liquorice. The traditional Chinese medicine oral liquid has the effects of clearing heat and resolving toxins, drying dampness and purging fire, invigorating the spleen and stomach, nourishing yin and generating fluid, and can be effectively used for preventing and treating pig viral diarrhea disease and bacterial diarrhea disease. The traditional Chinese medicine oral liquid has the characteristics of scientific prescription compatibility, wide raw material sources, simple preparation process, safe and wide application, and is suitable for industrialized breeding, and has clear efficacy, stable quality and strong market competitiveness.

The invention discloses a traditional Chinese medicine extract composition for assisting in reducing uric acid and a preparation method, and relates to the technical field of traditional Chinese medicine compositions, the traditional Chinese medicine extract composition comprises poria cocos, cichorium intybus, radix puerariae, gentiana macrophylla, rhizoma smilacis glabrae, Tibetan capillary, emblic leafflower fruit, glabrous sarcandra herb, Chinese starjasmine stem, wild buckwheat rhizome and white gourd. The traditional Chinese medicine extract composition breaks through the limitation of single existing uric acid reducing mechanism, plays a role in uric acid generation and excretion links, regulates a key pathway of uric acid metabolism through traditional Chinese medicine components to reduce uric acid generation, promotes urination to promote uric acid excretion, inhibits inflammatory mediator release and relieves oxidative damage by means of glabrous sarcandra herb and wild buckwheat rhizome components, and has a good application prospect. According to the traditional Chinese medicine preparation, the effect of multi-link synergistic effect of reducing uric acid, resisting inflammation and resisting oxidation is achieved, meanwhile, the blood uric acid level is reduced, the gout arthralgia symptom is relieved, the problem that an existing traditional Chinese medicine preparation cannot give consideration to comprehensive curative effect is solved, the requirement of a patient for comprehensive improvement of the illness state is met, and the overall effectiveness of treatment is improved.

The invention discloses a gentiana rigescens stem and leaf fermentation liquid mask preparation and a preparation method thereof. The gentiana rigescens stem and leaf fermentation liquid mask preparation is prepared from the following components in percentage by mass: 10-20% of gentiana rigescens stem and leaf fermentation liquid, 5-10% of glycerol, 2-4% of 1, 2-propylene glycol, 0.2-0.4% of sodium hyaluronate, 1.5-3% of sodium carboxymethyl cellulose, 0.2-0.4% of citric acid and the balance of deionized water. The mask preparation disclosed by the invention has excellent moisturizing performance, and the moisturizing degree can reach 90.5% in 24 hours in a high-humidity environment. Compared with a liquid before fermentation, the mask preparation after fermentation has definite antioxidant capacity, the clearance rate of DPPH free radicals is 67%, and the mask preparation shows good anti-aging activity. The compound disclosed by the invention can be used for inhibiting intestinal organs, has higher antibacterial activity on staphylococcus aureus, has the minimum inhibitory concentration of 2.5-5mu g / mL, can also be used for better improving the expression of inflammatory factors IL-1beta and IL-6 of intestinal organs, and has good anti-inflammatory activity. In addition, the mask preparation is good in stability and can be kept clear under the refrigeration condition.

To provide a skin care preparation which is derived from a natural product, is excellent in biological safety, and exhibits functions of preventing or improving skin roughness, improving the transparency of the skin, and suppressing cell aging by suppressing the secretion of inflammatory substances (cytokine and chemokine) in the skin.SOLUTION: An extract of Gentiana lutea belonging to the genus Gentiana of the family Gentianaceae and an extract of Bletilla striata belonging to the genus Bletilla of the family Orchidaceae are used as active ingredients for suppressing the secretion of inflammatory factor (cytokine and chemokine).SELECTED DRAWING: None

The application discloses a gentiana rigescens endophytic Streptomyces coelicoflavus and application thereof, and belongs to the technical field of microorganisms. The application relates to the gentiana rigescens endophytic Streptomyces coelicoflavus, which is preserved in the China General Microbiological Culture Collection Center on September 23, 2022, and the strain preservation name is MEP0301, and the preservation number is CGMCC No. 25778. The strain can significantly promote the increase of the total flavone content and the total triterpene content in the gentiana rigescens, and can be artificially cultured, is genetically stable, and is easy to be produced on a large scale. The strain can be used for artificial planting of the gentiana rigescens, can effectively improve the quality of medicinal materials, and has a good application prospect.

The invention provides an iridoid glycoside compound and a preparation method thereof. The iridoid glycoside compound is 2 '-O-(2, 3-dihydroxybenzoyl)-6'-O-acetyl sweroside, and the iridoid glycoside compound is a novel iridoid glycoside compound found from gentiana rigescens for the first time. The invention further provides a method for extracting, separating and purifying the compound from gentiana rigescens, the method comprises the steps of extraction, macroporous adsorption resin column chromatography, MCI microporous resin column chromatography, preparative high performance liquid chromatography separation and the like, the high-purity compound can be prepared through the method, the preparation process is simple, and industrial production is easy.

The invention belongs to the technical field of traditional Chinese medicine preparations, and discloses a traditional Chinese medicine composition capable of regulating spleen and kidney to promote children to grow tall as well as a preparation method and application thereof. The traditional Chinese medicine composition is prepared from rhizoma anemarrhenae, astragalus membranaceus, coptis chinensis, radix curcumae, liquorice, felwort, fructus alpiniae oxyphyllae, prepared rhizoma polygonati, acanthopanax, fructus psoraleae, semen cuscutae, glossy privet fruit, cistanche, prepared rhizoma cibotii, radix rehmanniae recen, prepared rehmannia root, agastache rugosus, schisandra chinensis, pericarpium citri reticulatae and poria cocos. The preparation method comprises the following steps: S1, preparing and pretreating raw materials: weighing the raw materials, cleaning, selecting and washing the raw materials, and then crushing the raw materials; s2, concentration and extraction: firstly decocting the pretreated raw materials, then separating, and finally concentrating to obtain the required traditional Chinese medicine composition. The traditional Chinese medicine composition can improve the problems of picky eating, anorexia, dyspepsia, sallow complexion, difficulty in falling asleep, night crying, dysphoria, irritability and the like, and can effectively promote children to grow tall.

The invention discloses a traditional Chinese medicine composition for treating diabetic lower limb vascular ischemia as well as a preparation method and application of the traditional Chinese medicine composition. The traditional Chinese medicine composition is prepared from the following sixteen raw material medicines according to a specific weight ratio: radix aucklandiae, pericarpium citri reticulatae, rhizoma cyperi, fructus aurantii, folium perillae, herba schizonepetae, radix saposhnikoviae, rhizoma seu radix notopterygii, radix angelicae pubescentis, radix gentianae macrophyllae, ramulus mori, loofah sponge, radix angelicae sinensis, rhizoma chuanxiong, cassia The traditional Chinese medicine composition can be prepared into various oral preparations, and the preparation method comprises the steps of crushing, extracting, filtering, concentrating and the like. Pharmacodynamic experiments show that the traditional Chinese medicine composition can significantly improve expression of angiogenesis factors, improve blood perfusion of lower limbs, promote angiogenesis and effectively treat diabetic lower limb blood vessel ischemia and symptoms such as limb numbness, pain and ulcer caused by diabetic lower limb blood vessel ischemia, and has the advantages of being definite in curative effect, high in safety and low in cost.

The present application relates to a kind of multi-effect herbaceous plant composite soothing repair composition and its preparation method, belong to the cosmetic technical field.The present application is by mixing glacial low deuterium water and superoxide dismutase to obtain A component, add D component (specific proportion nicotinamide mononucleotide (NMN) and modified hyaluronic acid microsphere) by the special interaction of the two with low deuterium water, form "triple synergistic carrier system", significantly improve the penetration and stability of active substance;B component is to mix hydroxyl asiaticoside and humectant.Meanwhile, the composite extract prepared by mixing the extract of radix stephaniae tetrandrae, the extract of gentiana and the extract of piper methysticum is C component, after mixing with A, B, D each component, low deuterium water can well carry the active ingredient in plant extract, hydroxyl asiaticoside and humectant in B component are mixed, can give full play to the moisturizing effect.The composition obtained after mixing A, B, C, D component has excellent soothing repair effect.

The invention discloses a series of benzoxane compounds as well as a preparation method and application thereof, novel benzoxane compounds 1a and 1b are extracted and separated from dry roots and rhizomes of a Gentiana plant Gentiana (Gentiana scabra Bge.), chiral resolution of the benzoxane compounds is realized for the first time, and the novel benzoxane compounds 1a and 1b have the advantages that the chiral resolution of the benzoxane compounds 1a and 1b is realized; and the anti-inflammatory activity evaluation is carried out on the obtained enantiomers 1a and 1b. The compounds 1a and 1b show significant nitric oxide (NO) release inhibitory activity, can significantly inhibit mRNA expression of cytokines IL-1beta, IL-6 and COX-2 in an inflammatory cell model, and show good development potential as lead compounds of anti-inflammatory drugs.

The application provides a traditional Chinese medicine composition which has excellent effect of treating liver cancer. The traditional Chinese medicine composition is composed of gentiana, dandelion, capillary random fiber, Chinese toona, eupolyphaga, monitor lizard, paris polyphylla, inula flower, ocher, tuber fleeceflower root, stone cypress, epimedium, cat's claw. The preparation method of the traditional Chinese medicine composition comprises the following steps: gentiana, dandelion and the like are respectively crushed and mixed, then extracted by using an organic solvent to obtain an organic solvent extract; the extract obtained by drying the organic solvent extract under reduced pressure is crushed, and ocher after crushing is added, so that the traditional Chinese medicine composition is obtained. The raw medicinal materials selected by the application are synergistic and mutually complementary in nature and effect, and jointly play a role in accordance with the overall concept of traditional Chinese medicine and inhibit the growth of cancer cells. The traditional Chinese medicine composition has the advantages of simple preparation process and the like, is suitable for commercial application, and has a wide application prospect.

The application discloses a kind of synchronous rapid detection and quality evaluation method of gentiana officinalis medicinal materials multiple components, belong to traditional Chinese medicine analysis and quality control technical field.The present application is directed to the defects that the comprehensive detection and analysis efficiency are difficult to be considered and the specificity of base source identification is insufficient in prior art, adopts phenyl-hexyl silane bonded silica gel chromatographic column, with acetonitrile-water as mobile phase, by specific three-stage gradient elution, in 20 minutes, the three major active ingredients of nucleosides, iridoid glycosides, flavonoids in gentiana are separated synchronously, the fingerprint containing 17 common peaks is constructed, the origin identification of multiple index component quantitative determination and gentiana and hard gentiana can be completed synchronously.The precision, stability and repeatability of the method are good, the detection efficiency and quality control comprehensiveness are greatly improved, and the method is suitable for industrialized batch rapid quality inspection of gentiana officinalis medicinal materials.

The invention discloses a method for extracting polysaccharide and bitter glycoside from radix gentianae, which comprises the following steps: by taking dry radix gentianae as a raw material, crushing the radix gentianae, adding an extraction solvent water, regulating the pH value by using sulfuric acid, performing ultrasonic extraction, filtering, regulating the pH value of an extracting solution by using ammonia water, centrifuging, concentrating, adding a polyethylene glycol aqueous solution into an extract, regulating the pH value by using ammonia water, performing ultrasonic extraction, and filtering to obtain the polysaccharide and bitter glycoside. And carrying out centrifugation, phase separation, ultrafiltration, nanofiltration and other steps to obtain an extract containing gentian polysaccharide and bitter glycoside. According to the method, polysaccharide and bitter glycoside are synchronously extracted and purified, the efficiency is high, no organic solvent is adopted, a large amount of energy consumption can be saved, production equipment has no anti-explosion requirement, the production process is simple and easy to control, the method has the advantages of being green, environmentally friendly, safe and efficient, and the obtained extract is high in purity.

The application relates to the cosmetic technical field, and particularly discloses a composition for micro-ecological balance and circadian rhythm repair and lightening and application. The composition for micro-ecological balance and circadian rhythm repair and lightening comprises the following components in mass percentage: glycyrrhiza glabra root extract 0.001%-1%, olea europaea leaf extract 0.1%-5%, hydraena elongata extract 0.1%-2%, gentiana rigescens 0.5%-3%, inulin 0.1%-5%, tripeptide-3 0.001%-0.01%, jasminum nudiflorum extract 0.5%-2%, and the balance is water. The composition has the advantages of systematically solving multiple problems such as skin redness, dullness and rhythm disorder.

The application discloses a traditional Chinese medicine composition for treating lumbar pain caused by diseases of the motor system and application thereof, and relates to the technical field of traditional Chinese medicines.The traditional Chinese medicine composition comprises yam, dogwood, prepared rehmannia, cassia twig, radix angelicae pubescentis, raw eucommia, rhizoma anemarrhenae, drynaria, frankincense, myrrh, chuanxiong, angelica sinensis, cyperus rotundus, achyranthes bidentata, amomum villosum, tangerine peel, gentiana, polygala, and licorice.The traditional Chinese medicine composition has the effects of tonifying liver and kidney, strengthening bones and muscles, promoting blood circulation to remove meridian obstruction, and relieving swelling and pain, and can be used for treating lumbar pain caused by various diseases of the motor system, such as lumbar hyperosteogeny, intervertebral disc herniation, lumbar vertebra hypertrophy, spinal stenosis, lumbar fracture, spinal canal tumor, acute and chronic trauma or strain of the lumbar region, lumbar muscle strain, and ankylosing spondylitis, and has outstanding curative effects on acute and chronic lumbar pain.

The invention discloses a gentiana rigescens stem and leaf fermented feed additive with anti-inflammatory and immunomodulatory effects, the optimal gentiana rigescens stem and leaf and lactobacillus plantarum fermentation catalysis process are screened out through an orthogonal process, a fermentation product is obtained, swertiamarin, caffeic acid and loganic acid with higher anti-inflammatory activity are newly generated, and the anti-inflammatory and immunomodulatory effects of the gentiana rigescens stem and leaf fermented feed additive are improved. And the content of active ingredients such as gentiopicroside is increased. By establishing a DSS-induced mouse ulcerative colitis model and determining related indexes, the feed additive can significantly improve mouse colitis symptoms, reduce DAI score, reduce weight loss, inhibit colon shortening and reduce expression of inflammatory factors IL-1beta and IL-6 through intragastric administration, and has significant anti-inflammatory and immunomodulatory effects. According to the invention, innovative application of non-medicinal parts of traditional Chinese medicinal materials in the field of feed can be promoted, efficient utilization of agricultural by-products is realized, and a wide application prospect is provided for sustainable development of green animal husbandry.

The present application relates to a kind of mild moisturizing soothing composition and its application, the composition includes the following weight parts of component: 5-10 parts of lactobacillus / fermentation product of algal extract, 2-5 parts of capparis zeylanica fruit extract, 3-5 parts of olive fruit oil and 10-15 parts of schisandra fruit extract-gentiana root extract, four synergistically improve the moisturizing soothing effect of composition.The schisandra fruit extract-gentiana root extract of the present application is biotransformed and synergistically metabolized by compound fermentation bacteria, significantly improves the utilization rate of active ingredients in schisandra fruit extract and gentiana root extract, and expands its efficacy range, can play the role of regulating inflammatory response, reinforcing skin barrier, solving the problem of eczema skin barrier, reducing scratching skin stinging discomfort, reducing eczema recurrence, solving the problem of dry peeling caused by indoor and outdoor temperature difference, dry area, reducing water loss and antioxidant damage and other multiple effects.

The invention provides a planting method for promoting growth of gentiana dahurica fisch and improving commodity grade, and belongs to the technical field of medicinal plant cultivation, the planting method comprises the following steps: selecting chestnut soil or sandy loam with appropriate altitude, annual average temperature, annual rainfall, pH and organic matter; covering black films after deep ploughing and base fertilizer application; first-level seedlings are cultivated through the seeds; planting in a fixed distance for 3-year, 4-year and 5-year; irrigating, topdressing and picking buds for 2-3 times; digging, and dividing into first-class, second-class and third-class products according to the diameter of the lower part of the reed; according to the method, by constructing a comprehensive evaluation system for multiple indexes including plant height, leaf length, leaf width, root diameter, root length, seedling keeping rate, yield and commodity grade, an optimal density scheme for different growth years is determined, so that a synergistic promotion effect is formed among the indexes of the gentiana dahurica fisch.

The application provides a traditional Chinese medicine preparation for dispelling wind and removing dampness and application, and relates to the technical field of traditional Chinese medicine preparation, wherein the traditional Chinese medicine preparation is composed of ten traditional Chinese medicines including Lonicera japonica, Spatholobus suberectus Dunn, silkworm sand, gentiana, safflower, persica, cortex fraxini, ardisia japonica, medicated leaven and honeycomb; the traditional Chinese medicine preparation can significantly reduce the swelling degree of ankle joint of an acute gouty arthritis model rat, reduce the expression level of serum TNF-alpha, IL-1beta and IL-6 inflammatory factors, and reduce the content of serum uric acid, creatinine and XOD, so as to achieve the effects of anti-inflammation and analgesia, reduction of blood uric acid, and the like; the clinical test results show that the traditional Chinese medicine preparation can reduce the pain degree of a patient, reduce the levels of inflammation related factors TNF-alpha and IL-1beta in synovial fluid of a knee joint of the patient, reduce the inflammation indexes WBC, ESR and CRP in serum, reduce the inflammation reaction of the patient's body, reduce the incidence of adverse reactions, and provide a new traditional Chinese medicine preparation with high safety and good curative effect for the treatment of acute attack of gout.

The invention provides a skin care composition with a synergistic anti-allergy effect and a skin care product containing the skin care composition. The skin care composition with the synergistic anti-allergy effect is prepared from the following components in parts by weight: 10 to 25 parts of plant extract, 10 to 15 parts of humectant and 50 to 90 parts of water, wherein the plant extract is selected from a mixture of a radix gentianae extract, a stephania tetrandra extract, a piper nigrum root extract and a radix sophorae flavescentis extract, and the mass ratio of the radix gentianae extract to the stephania tetrandra extract to the piper nigrum root extract to the radix sophorae flavescentis extract is (5-10): (5-10): (5-10): (1-5). In the implementation process, different plant extracts are mixed for use, and the mass ratio of the plant extracts is controlled, so that the effects of resisting allergy, diminishing inflammation, repairing and moisturizing are achieved; the plant extract has the effects of bacteriostasis and repair, and can fundamentally solve the problem of skin allergy.