3196 results about "PANAX NOTOGINSENG ROOT" patented technology

This invention provides a composition for heart disease comprising extracts from raw herbs of 80.0-97.0% Radix Salviae Miltorrhizae, 1.0-19.0% Panax Notoginseng and 0.1-1.0% Borneol and its active ingredients. This invention also provides a method for preparing said composition and the active ingredients of the composition. Finally, this invention provides various uses of said compositions and the active ingredients.

The invention pertains to the technical field of biology and medicine, and relates to a bacterial strain of streptomyces fradiae NTGA-334 with a preseravation no. of CGMCC No.2074, and a process for using the bacterial strain to ferment and transform Compound K in glycol group in various notoginsenosides so as to prepare 20-O-beta-D-glucopyranoside-20 (S)-protopanaxadiol. The culture media are Gause's no.1, ISP2, corroding acid (HSG culture medium) and asparagine culture medium. During the fermentation, the dosing proportions of various notoginsenosides are 0.1-10% (w / v), fermenting temperature is 18-50 DEG C, dynamically adjusted pH value of 0.1-35%(w / v) aqueous ammonia is 0.1-30% (w / v). The invention transforms and ferments in a scaled way various notoginsenosides, prepares Compound K, provides a streptomycete stain that is of steady condition, simple nutrition requirement and good growth, and provides a process for fermenting and separating by a simple and easy fully automatic fermenting tank. Using this bacterial strain and process to produce Compound K, the production cost is low, the foreign matter is less, and the yield rate is high.

The invention discloses bacillus amyloliquefaciens (Ba 168) and a preparation method and an application of the bacillus amyloliquefaciens, and aims at providing a biological control method of phytopathogens. The bacterial strain is preserved in the China General Microbiological Culture Collection Center (CGMCC), and the preservation number is CGMCC No.6462 on August 21, 2012. The bacterial strain is separated and obtained from soil in the Qinling Mountain virgin forest, and subjected to bacteria activation, shake-flask fermentation, seed liquid fermentation and large tank fermentation to obtain fermentation liquid; and the fermentation liquid is subjected to filtration and concentration, ultrafiltration membrane separation, and spray drying and packaging to be prepared into bactericide. The bacillus amyloliquefaciens has the advantages that the bacillus amyloliquefaciens can well prevent and cure bighead atractylodes rhizome root rot, American ginseng root rot, pseudo-ginseng root rot and other root rot caused by fusarium oxysporum.

The invention discloses a dressing composition used for inhibiting scars and accelerating wound healing and application thereof. The dressing composition consists of chitosan, acidic polysaccharide and panax notoginseng saponins in a weight proportion of 100:10-50:10-100, wherein the chitosan is selected from chitosan, chitosan lactate, acetate and hydrochloride; the acidic polysaccharide is selected from sodium carboxymethyl chitosan, sodium hyaluronate, zinc hyaluronate, sodium alginate and sodium carboxymethyl cellulose; and the panax notoginseng saponins accounts for no less than 40.0 percent of the total weight of ginsenosides Rg1 and Rb1. The formulations of the dressing composition are xerogel powder, capsules, gel membranes, hydrogels and fiber coatings. The dressing composition is used for wounds, burns, scalds, crush injuries, skin ulcers, gastroenteric ulcers and no healing of the wounds, has the advantages of rapid hemostasis, exudate reduction, moisturizing, air permeability, bacteriostasis, inflammation diminishing, itch relieving, no adhesion, effective inhibition of scarring, remarkable reduction of wound healing time and no need of replacing dressings, so that thedressing composition basically meets requirements of perfect functional external dressings.

The invention discloses panax notoginseng active ingredient-containing medicinal toothpaste and a preparation method and application thereof. The panax notoginseng active ingredient-containing medicinal toothpaste comprises 0.1 to 0.4 weight percent of total panax notoginseng saponins and 0.2 to 0.5 weight percent of panax notoginseng polysaccharide which are panax notoginseng active ingredients,abrasive, a wetting agent, surfactant, a foaming agent, adhesive, a stabilizing agent and deionized water. The preparation method for the toothpaste comprises the following steps of: preparing materials, mixing, grinding, and degassing to obtain a toothpaste body. According to the toothpaste, total panax notoginseng saponins and panax notoginseng polysaccharide are used as the core functional components of the toothpaste, so that the toothpaste has the function of cleaning teeth, and the obvious effects of promoting recovery of dental ulcer, gingivitis and periodontitis, inhibiting swelling and aching of gums, relieving bleeding of gums, and delaying gingival atrophy and aging. The total panax notoginseng saponins and the panax notoginseng polysaccharide which are used as the active ingredients are natural plant extract, so that damage to ecological environment of normal flora in an oral cavity can be avoided, and the panax notoginseng active ingredient-containing medicinal toothpasteis suitable to be used for a long tome and is good in effect.

The invention discloses a panax notoginseng polysaccharide extract and a preparation method, preparations and applications thereof. The panax notoginseng polysaccharide extract is prepared by taking waste residues produced after panax notoginseng saponins are extracted as raw materials through the steps of extraction, concentration, purification, drying, crushing and detection, wherein the content of panax notoginseng polysaccharides is not less than 15%. The preparation method of the panax notoginseng polysaccharide extract comprises the steps of extraction, concentration, purification, drying, crushing and detection, and specifically comprises the steps of adding waste residues produced after panax notoginseng saponins are extracted into purified water for extracting, carrying out filtration and concentration on the obtained object, adding ethanol into the obtained object for precipitating, and carrying out filtration, purification and drying on the obtained product so as to obtain a target dried product. Pharmaceutical excipients are added into the panax notoginseng polysaccharide extract to be prepared into powder, capsules, granules, tablets or pills; and the panax notoginseng polysaccharide extract is applied to the preparation of antineoplastic drugs and immunity enhancing drugs. According to the invention, waste residues produced after panax notoginseng saponins are extracted are reused, thereby changing waste material into things of value, facilitating the comprehensive utilization of panax notoginseng resources, reducing the cost and improving the economic benefits.

The invention relates to tartary buckwheat-maize instant noodles, which are prepared from the following materials in parts by weight: 300-340 parts of maize flour, 80-90 parts of mung bean starch, 60-70 parts of tartary buckwheat, 30-40 parts of millet, 100-120 parts of green tea juice, 50-60 parts of oyster mushroom juice, 60-70 parts of honey, 20-30 parts of lemon, 40-50 parts of chufa and the like. The invention discloses the tartary buckwheat-maize instant noodles in which tartary buckwheat and millet are added so that very good functions of treating hypertension, hyperlipidemia and hyperglycemia and nourishing the stomach are achieved. In addition, extracts of coreopsis tinctoria flowers, cushaw flowers, panax notoginseng powder, hawthorn and the like have the efficacies of resisting and preventing cancer, reducing blood fat and blood pressure, eliminating fat and losing weight. Therefore, the tartary buckwheat-maize instant noodles are health food.

The invention relates to an ecological planting method of panax notoginseng and belongs to the technical field of planting of traditional Chinese medicinal materials. The method comprises specific steps as follows: land selection and preparation; ditching and plot arrangement; planting of panax notoginseng; piling and shed building; net and film covering; field management (including film uncovering for germination, weed removal, irrigation and drainage, shade frame adjustment, removal of flower buds, fertilization, disease and pest prevention and control as well as stalk cutting for passing of the winter); digging of the panax notoginseng. The method is based on the bionic cultivation principle of the traditional Chinese medicinal materials, physiological and biological characteristics of the panax notoginseng are combined, the ecological environment suitable for growth and development of the panax notoginseng is created, the resistance of the panax notoginseng is enhanced through agricultural comprehensive prevention and control measures, field diseases and pests are reduced, high-quality and green panax notoginseng is produced, and the method is simple and easy to implement, conforms to the development direction of ecological planting of medicinal plants at home and abroad and is a technological revolution in cultivation of the panax notoginseng.

The invention relates to an environment-friendly prevention and control method of panax notoginseng diseases and belongs to the technical fields of plant disease prevention and control and plant cultivation. The prevention and control method comprises land selecting and soil preparation, panax notoginseng planting and seed handling and growing period management, wherein thoroughly-decomposed cow dung, begasses, compound fertilizers and plant ash are mixed according to the volume ratio of 5:4:1:1; 6000-10000kg / hm<2> of improved soil is adopted; xiandi, 1cm of marigold limbs and trichoderma harzianum are applied after ditching and less xiandi is used for mixing with roots before transplanting; crofton weed and the marigold limbs are covered on a moisture face after transplanting, bottom-ventilated row covers are constructed, two sides of the bottom-ventilated row covers are vertical to the ground, and the bottom-ventilated row covers are 15cm in length, 1.8m in width and 1.2m in arc height; the trichoderma harzianum and the marigold infusion are applied in a sprayed mode according to the ratio of 1:200 after emergence of seedling to irrigate roots, and 100g / L of jasmonic acid methyl ester are applied to leaf faces in a sprayed mode. The environment-friendly prevention and control method has the advantages of being simple in operation, low in cost and easy to popularize, protecting the environment, being environment-friendly and the like, lays a good foundation to pollution-free planting of the panax notoginseng and has good economic benefits, ecological benefits and social benefits.

The invention discloses a method for planting Panax notoginseng. The method includes the following steps of firstly, selecting a land, wherein the geographical condition, weather condition, soil condition, production requirement and environment quality of the land are suitable for planting the Panax notoginseng; secondly, plowing and improving the land; thirdly, setting up an arch shed and covering the arch shed with a sunshade net; fourthly, arranging ridges, digging pits, arranging the bed and preventing soil insects; fifthly, selecting, germinating, sowing and watering seeds; sixthly, managing plantation in the first year, namely, removing a film so that seedlings can emerge, adjusting luminance in a shed, conducting irrigation and drainage, removing grass and applying fertilizers, and conducting ventilation drying and pest control; seventhly, managing plantation in the second year to the third year, namely, shearing stalk and applying fertilizers, removing a film so that seedlings can emerge, adjusting luminance in the shed, conducting irrigation and drainage, conducting ventilation drying, applying fertilizers, picking buds, and conducting pest control; eighthly, managing plantation in the fourth year, namely, conducting field management, picking and digging, cleaning, drying and storing. By improving and adjusting related technological steps and parameters in Panax notoginseng plantation, the method is more reasonable and high in operability, and manual plantation of the Panax notoginseng is achieved.

The invention discloses a double-formula medicine used for treating insomnia, and a preparation method thereof. With existing insomnia-treating medicines, a simultaneous kidney invigorating, liver soothing and tranquilizing function can hardly be achieved. The medicine assists in solving the problem. With the medicine, various depressive insomnias can be treated with multiple targets, multiple links and multiple approaches. The double-formula medicine provided by the invention is composed by a formula A and a formula B. The formula A is composed of a Tiantai radix linderae extract, a corydalis tuber extract, panax notoginseng powder, a Chinese clematis root and rhizome extract, black common monkshood daughter root, an eucommia extract, and the like. The formula B is composed of a white mulberry root-bark extract, a psoralea corylifolia extract, a dipsacus asper extract, a silktree albizia bark extract, an oriental waterplantain tuber extract, an asiatic plantain seed extract, a Chinese arborvilae seed extract, a thinleaf milkwort root extract, a spine date seed extract, a common cnidium fruit extract, and the like. The invention also provides a preparation method of the double-formula medicine. With the method, various depressive insomnias can be treated with multiple targets, multiple links and multiple approaches. The medicine is advantaged in safe treatment, no toxic or side effect, fast effect, and thorough treatment.

The invention belongs to the medicine technical filed, in particular to a preparation method of monomeric compound ginsenoside Rg1, ginsenoside Rb1 and total arasaponin and the application in the medicine field thereof. The fresh medicinal material, the dried medicinal material and the medicinal material on the market of Panax notoginseng are taken as the raw materials; according to the polarity and the solubility property of a compound, separation and purification are carried out by adopting the solvent extraction method, the crystallization process and the chromatography and total arasaponin powder is prepared by combining the common drying means, such as decompression concentration drying, freeze drying, vacuum drying and the like; by carrying out one or more methods of recrystal, normal phase, opposite phase silica gel column chromatography, daiamid column chromatography and sephadex chromatography and the like on the powder, the ginsenoside Rg1 and the ginsenoside Rb1 monomers are prepared. The medicines which take the ginsenoside Rg1 and the ginsenoside Rb1 monomers or the total arasaponin as the active ingredients can be used for preventing and / or curing the senile dementia, the neurodegenerative diseases, the cerebrovascular disorder, various dysmnesia, the central lesion and other diseases.

The invention belongs to the cultivation technology of Chinese herbal medicines, and relates to a process method for the continuous cropping soil of Panax Notoginseng. The process method specifically comprises the following steps: (1) after the collection of Panax Notoginseng in July-August (the collection of the winter Panax Notoginseng is in December), immediately clearing the plant residues, such as Notoginseng stems, leaves, hair roots and the like, in the furrows, removing the covering materials, such as mulching film, straw, cogon or pine needle, on the surface of the furrows; (2) broadcasting 9000-13500 kg of crushed rape-seed meal per hectare, intertilling the land by artificial or mechanical method, ploughing the rape-seed meal under the soil in the furrows evenly; (3) irrigating enough water to the furrows in the Notoginseng shed so that the soil in the shed reaches the saturated state of water intake; (4) covering the furrow surface in the Notoginseng shed by an unbroken plastic thin film whose peripheries are tamped down by heaping the soil to prevent contact with air; (5) recovering the thin film till November (the field of the winter Panax Notoginseng is in next December), turning over the soil, and planting the Panax Notoginseng anew in December. The invention overcomes the Panax Notoginseng continuous cropping obstacles to a certain degree, has no pollution to the environment, provides organic fertilizer for the growth of Panax Notoginseng better, and has good social, ecological and economic benefits.

The invention discloses a medicine combination of adjusting hypertension, hyperlipidemia and angina, consisting of astragalus, panax, salvia, cynostemma, americanwater plantain, ginkgo biloba, panax notoginseng, hawthorn, mythic fungus, schisandra, fragrant solomonseal rhizome and wolfberry fruit. The medicine combination of the invention has the advantages of invigorating qi and replenishing yin, activating blood and stabilizing pain, nourishing heart and calming mind, replenishing qi and nourishing blood, supplementing spleen and invigorating kidney, promoting moisture and urination, clearing heat, detoxifying and cooling blood, reducing tension, clearing liver, reducing lipid, nourishing yin, improving eyesight, reinforcing kidney, reducing sugar, dual directionally regulating and etc. Meanwhile, the medicine has an obvious effect on treating hypertension, hyperlipidemia, angina, and the hypertensions and anginas caused by unknown reasons.

The invention provides an oral capsule used to cure the pains in neck, waist and legs, as well as the preparation method thereof. The oral capsule is composed of 36 species of traditional Chinese medicines by the weight ratios and the formula as follows (takes preparing 1000 oral capsules as the standard): heracleum hemsleyanum michaux 9 to 90 gram, gentian root 9 to 90 gram, ledebouriella seseloides 9 to 90 gram, asarum herb 3 to 30 gram, viscum album 12 to 120 gram, angelica 9 to 90 gram, white peony root 9 to 90 gram, ligusticus wallichii franchet 8 to 80 gram, arable land 9 to 90 gram, cortex eucommiae 10 to 100 gram, butter 10 to 100 gram, butcher shop 9 to 90 gram, Japanese teasel 12 to 120 gram, cassia bark 5 to 50 gram, codonopsis pilosula 12 to 120 gram, astragalus root 12 to 120 gram, rhizoma gastrodiae 6 to 60 gram, Chinese wolfberry 12 to 120, kudzu root 10 to 100 gram, akebiaquinata 10 to 100 gram, atractylis ovata 10 to 100 gram, clematis chinensis 10 to 100 gram, safflower 6 to 60 gram, cortex moutan 6 to 60 gram, mastic 6 to 60 gram, common myrrh 6 to 60 gram, Chinese flowering quince 10 to 100 gram, drynaria 12 to 120 gram, caulis spatholobi 12 to 120 gram, panax notoginseng 10 to 100 gram, crow 10 to 100 gram, dried body of scorpion 9 to 90 gram, centipedes 2 to 15, dragon blood 10 to 100 gram, eupolyphaga 12 to 120 gram and broiled licorice root 0 to 30 gram; the quality of all traditional Chinese medicines satisfies the standard of the Chinese Pharmacopoeia, and the traditional Chinese medicines are made into powder according to the Chinese traditional medicine preparation method, and are then canned into capsules.

The invention provides a cosmetic composition containing a TCM (traditional Chinese medicine) extracting solution. The TCM extracting solution is composed of the following Chinese herbal medicines in parts by weight: ginseng, angelica sinensis, snow lotus herbs, folium artemisiae argyi, panax notoginseng, olibanum, fortune eupatorium herbs, radix pseudostellariae, agrimonia pilosa ledeb, radix polygonati officinalis, corn cervi pantotrichum, radix gentianae, flos magnolia, selaginella tamariscina, peony, Chinese herbaceous peony, herba centellae, pogostemon cablin, rhizoma ligustici wallichii, poria cocos, radix aucklandiae, anthemis tinctoria, and fructus lycii. The invention also provides a preparation method of the cosmetic composition containing a TCM extracting solution. The cosmetic composition disclosed by the invention is a cosmetic product which is implemented by the collaborative application of multiple TCM skin care products, and is good in extraction effect and high in quality, and each product reaches the international standards.

The invention discloses a health-care food for resisting aging and enhancing immunity and a preparation method of the health-care food. The health-care food comprises the following components by mass percent: 20-40 percent of broken-wall haematococcus pluvialis powder, 15-30 percent of broken-wall pine pollen, 10-20 percent of spirulina powder, 5-10 percent of ultramicro maca powder, 10-15 percent of ultramicro American ginseng powder, 6-10 percent of ultramicro moringa seed powder and 3-5 percent of panax notoginseng saponins. The health-care food for resisting aging and enhancing immunity is prepared by the following steps: mixing the broken-wall haematococcus pluvialis powder, the broken-wall pine pollen and the spirulina powder to obtain mixed powder; subjecting the mixed powder to enzymolysis to obtain an enzymolysis product; and adding the panax notoginseng saponins, the ultramicro maca powder, the ultramicro American ginseng powder and the ultramicro moringa seed powder to the obtained enzymolysis product, and mixing the obtained mixture. The formula of the health-care food provided in the invention is reasonable, is safe and reliable, has a remarkable effect and has an excellent synergistic effect in resisting aging and enhancing immunity. The health-care food provided in the invention has the efficacy of resisting oxidation, enhancing immunity, supplementing various nutritious substances, tonifying qi, nourishing yin, promoting the secretion of saliva or body fluid, relieving restlessness, invigorating the circulation of blood, reducing blood pressure and blood fat, and the like.

The invention discloses a healthcare wine for improving immunity. The healthcare wine is prepared from the following components by weight (gram): morinda officinalis, loranthus parasiticus, semen cuscutae, Chinese yam, radix ophiopogonis, angelica sinensis, fructus schizandrae, flos carthami, ligusticum wallichii, medicated leaven,ginger mangnolia officinalis, unhairing rosa laevigata michx, polygonum multiflorum, pulp of dogwood fruit, earthworm, clematis chinensis, pawpaw, herba epimedii, rhizoma cibotii, shawanzi (Chinese character), codonopsis pilosula, poria cocos, semen coicis, asparagus fern, radix scrophulariae, polygala tenuifolia, peach seed, panax notoginseng, rhizoma dioscoreae nipponicae, costusroot, jujube, mulberry, radix glycyrrhizae, radix sophorae flavescentis, eucommia, dipsacus root, fructus rubi, rhizoma atractylodis macrocephalae, radix rehmanniae, radix polygonati officinalis, rhizoma acori graminei, radix paeoniae rubra, sinapis alba, radix paeoniae alba, glossy privet fruit, fritillaria thunbergii miq, cuttlebone, notopterygium, hippocampus, astragalus membranaceus, pinellia ternate, cistanche salsa, rhizoma drynariae, cynomorium songaricum, cortex phellodendri, rhizoma atractylodis, radix rehmanniae preparata, dendrobium, salviae miltiorrhizae, cortex moutan, hawthorn, fructus cnidii, fatmelon kernel, dry longan, pericarpium citri reticulatae, wolfberry, lily and malt.

The invention discloses a method for improving notoginseng main functional components through fermentation, which comprises following steps: (1)culturing bacillus LB inclined surface seed for 24 hours, moving it to LB liquid culture medium, culturing and getting culture liquid; (2)mixing notoginseng with water, disinfecting and getting notoginseng convertible culture medium; (3)inoculating culture liquid got in step (1)to notoginseng convertible culture medium, converting notoginseng; (4)drying converted notoginseng until the weight is constant, getting target product. The main functional component content after biological fermentation is increased by 4-6 times, the extract liquid amount is increased by about two times. The invention provides good method and platform for further development and utilization of Chinese traditional medicine.

The invention relates to a traditional Chinese medicine preparation for treating cardiovascular and cerebrovascular diseases, mainly containing one or more of Salvia miltiorrhiza, folium ginkgo, panax notoginseng, kudzuvine root Pueraria lobata, rhizoma ligustici wallichii, hawthorn and lotus leaf. The preparation method comprises the steps of selecting one or more of the Salvia miltiorrhiza, the folium ginkgo, the panax notoginseng, the kudzuvine root Pueraria lobata, the rhizoma ligustici wallichii and the hawthorn and lotus leaf, decocting, extracting active ingredients and concentrating the extracting solution to a certain concentration to obtain the Chinese traditional medicine preparation. In addition, the concentrated solution can be further made into capsules, tablets, granules, oral liquid, pills, pulvis, injection and sustained and controlled release preparations. Toxicologic and pharmacologic agent experiments show that the invention has no toxic side effect, is safe to use, has the functions of promoting blood circulation, remove blood stasis, reducing fat, freeing channels and eliminating phlegm and is suitable for phlegm stasis internal-block type cardiovascular and cerebrovascular diseases.

The invention discloses a traditional Chinese medicinal preparation for stopping bleeding and disinfecting, which is prepared from the following traditional Chinese medicinal materials by weight: 2-8 parts of Panax notoginseng, 2-8 parts of Flos Lonicerae, 2-6 parts of ciliate desert-grass, 2-6 parts of Artemisia argyi leaf, 1-5 parts of Corydalis yanhusuo, 1-5 parts of Imperata cylindrica root, 2-6 parts of Salvia miltiorrhiza, 1-4 parts of Ramulus Uncariae Cum Uncis, 1-4 parts of Angelica dahurica, 1-5 parts of Portulaca oleracea, 1-3 parts of Herba Taraxaci, 0.5-1.2 parts of Fuligo Plantae, 1-3 parts of Artemisia annua, and 1-3 parts of borneol. The traditional Chinese medicinal preparation for stopping bleeding and disinfecting is appropriate for cleaning and disinfecting the wound of skin, mucosa or tissue in a general surgical operation and stopping bleeding and disinfecting the traumatic wound. The traditional Chinese medicinal preparation of the invention is used to stop bleeding of the wound, resists infection, has remarkable curative effect, is fast to stop bleeding with no secondary infection of the wound, and has no toxic and side effects and no irritation. The effective rate is 100% and no scars are left after recovery. The medicines adopted by the invention are all folk herbs in China and convenient to pick up, and low in cost.

The invention discloses a method for preparing ginseng rare anti-cancer saponin Compound K from composite bacteria, and belongs to the fields of functional food and pharmacy. According to the method, RB1 or ginseng, American ginseng and panax notoginseng serve as raw materials, 1 to 5 percent of sugar and milk powder are added, preferable saccharomycetes for producing beta-glucosaccharase, lactic acid bacteria and bifidobacterium are adopted, fermentation is conducted at 30 to 37 DEG C for 5 to 14 days, microbial transformation of the compound bacteria is conducted, and the rare ginseng containing saponin C-K is obtained. The obtained fermented ginseng powder and panax notoginseng powder have strong and attractive fragrance and good taste, and the health-care effect and the nutritional value of ginseng and panax notoginseng are greatly improved.

The invention relates to a herbal drug for hemorrhoids with natural plants, in particular to a drug with specific formulation, comprising a plurality of active pharmaceutical ingredients, certain amount of penetration enhancer and certain amount of pharmacyeutical adjuvant with the following weight proportion. The active pharmaceutical ingredient comprises one hundred shares of sophoricoside, eighty shares of panax notoginseng, one hundred and ten shares of lightyellow sophora root, one hundred shares of bletilla striata, one hundred shares of common cnidium fruit, one hundred shares of patrinia scabiosaefolia link, sixty-five shares of moxa leaf, eighty shares of pursslane, sixty-five shares of honeysuckle, sixty-five shares of parsnip, fifty shares of alumen, fifty shares of borax, five shares of borneol, and thirty shares of licorice. The penetration enhancer comprises a certain amount of laurocapram and a certain amount of propanediol with the weight proportion of eighty to fifteen - thirty; the adding amount of the penetration enhancer is point zero eight to point four percent of the weight of the active pharmaceutical ingredient. The drug has the advantage of being more effective than oral drugs and external lotion due to full play of effective ingredients by adding penetration enhancer in specific prescription and formulation.

The invention discloses a method for biotransformation of Panax notoginseng (Burk.) F. H. Chen medicinal materials by using Monascus purpureus. The method mainly comprises the following operating steps of: 1) preparation of Monascus purpureus strains; 2) preparation of Panax notoginseng (Burk.) F. H. Chen culture medium; and 3) fermentation and culture to obtain fermentation products containing active components, product post-treatment and detection of major efficacy components. By using the method for fermenting the Panax notoginseng (Burk.) F. H. Chen by using the Monascus purpureus provided by the invention and by directly using Panax notoginseng (Burk.) F. H. Chen raw medicinal materials as fermentation substrate, through one-step fermentation process, medicinal components, i.e. Panax notoginseng (Burk.) F. H. Chen and Monascus purpureus are simultaneously obtained, the culture is enabled to have dual effects of the Panax notoginseng (Burk.) F. H. Chen and the Monascus purpureus, the products contain lovastatin which is a lipid-decreasing active component according to experiments, the type and the content of saponin are obviously changed, and rare saponin with higher pharmacological activity is produced.

The invention relates to the technical field of Chinese herb planting, in particular to a panax notoginseng planting method. The panax notoginseng planting method is characterized in that whole process management of panax notoginseng planting is realized by means of performing seed selection, seed treatment through seed dressing agents, sowing and plant growing and row spacing control in planting season of panax notoginseng, and taking water retention and fertilizer-saving measures and managing the seedling implanting stage and the seedling stage. The panax notoginseng planting method has the advantages that by the adoption of special treatment of seeds, rational close planting, sowing in good time and effective fertilization, survival rate of panax notoginseng plants is increased effectively, and accordingly planting benefit is improved; the method is simple and feasible, and can be grasped by ordinary farmers.

The invention belongs to the technical field of prevention and control of plants diseases and particularly relates to a trichoderma koningiopsis T5-1 bacterial strain and an application thereof in improvement of growth of panax notoginseng and prevention and control of root rot. The bacterial strain is named trichoderma koningiopsis, and is assigned the accession number of CGMCC No. 12779 in China General Microbiological Culture Collection Center. The trichoderma koningiopsis T5-1 bacterial strain has developed mycelia and fluffy and dense aerial mycelia, and is free of generation of pigments. The trichoderma koningiopsis T5-1 bacterial strain can improve growth of panax notoginseng and also can inhibit growth of root rot fungus. The bacterial strain can be hyper-parasitized on the root rot fungus, so that spore production of the root rot fungus is inhibited by means of volatile organic compounds from the bacterial strain in a sealed condition. The bacterial strain lays a good foundation for development and utilization of bio-bacterial fertilizers.

The invention discloses a preparation method of an anti-allergy and anti-pruritus composite plant extract. The preparation method comprises the following steps of (1) taking panax notoginseng, adding water in the panax notoginseng, performing ultrasonic cell wall-breaking treatment for subsequent use, and pulverizing honeysuckle and chamomile for subsequent use; (2) uniformly mixing the panax notoginseng, the honeysuckle and the chamomile which are pretreated in the step (1), and adding cellulase and maltase to carry out enzymolysis so as to obtain enzymatic hydrolysate; and (3) extracting the enzymatic hydrolysate by using extracting solvent to obtain extracting solution, and performing follow-up treatment on the extracting solution to obtain the anti-allergy and anti-pruritus composite plant extract. The invention also discloses the anti-allergy and anti-pruritus composite plant extract prepared by the method. The composite plant extract is safe and non-irritant, and can be used for preparing anti-allergy and anti-pruritus medicines or cosmetics. The anti-allergy and anti-pruritus effect of the anti-allergy and anti-pruritus composite plant extract is obviously higher than that of a plant extract prepared by a traditional method.

The invention discloses a method for preparing a probiotic fungicide for preventing panax notoginseng continuous cropping diseases, belonging to the field of microbial fermentation. The method comprises the steps of fermenting, namely respectively culturing individual production strains of the probiotic fungicide into a primary seed solution, inoculating to a culture medium which takes corn flour-potato-bean pulp as a principle component for performing aerobic mixed fermentation and enlarged cultivation, wherein the production strains are selected from seven bacteria-fungi such as bacillus subtilis; and adsorbing and immobilizing the fermentation end products to turf charcoal so as to prepare a solid fungicide. The continuous cropping diseases which are ubiquitous in the conventional panax notoginseng plantation technology are solved, and continuous cropping and continuous harvest can be realized in the panax notoginseng planting fields after the panax notoginseng is planted for 2-3 years. The preparation method has the outstanding characteristics of low production cost, short fermentation period and high flora density. According to the fungicide, dead seedlings, yellow seedlings, wither, dried leaves, root rot and other ecological soil symptoms in the panax notoginseng planting process can be prevented; and meanwhile, according to the method, root growth can be promoted, the soil is loosened, strong seedlings are cultivated, and pesticide and fertilizer residues are removed and the obvious function of ecologically repairing the soil is achieved.

The invention relates to panax notoginseng saponins medicine combination and the application thereof, which are characterized in that the active ingredient is composed of panax notoginseng saponins which contains notoginsenoside R1, ginsenoside Rg1, ginsenoside Rb1, ginsenoside Re, ginsenoside Rd, ginsenoside Rb3 and ginsenoside Rb2; the combination with different contents and ingredients of saponins are prepared; the combinations have different treatment effects.

The invention relates to a plaster for treating rheumatism which is prepared from 40 traditional Chinese medicinal materials including syngnathus, pubescent angelica, angelica, agkistrodonbungarus minimus, peach kernel, safflower, phellodendron, radix sileris, catnip, asarum, pinellia ternate, yazao, erhua, forsythia, pangolin, nux vomica, rhizoma gastrodiae, panax notoginseng, papaya, hyssop, cortex eucommiae, cassia twig, olibanum, myrrh, angelica, coptis, notopterygium, fritillaria, sophora, whole worm, centipede, dragon's blood, radix auckladiae, realgar, musk, clove, borneol, astragalus, sesame oil and guangdan. The plaster has special curative effect for treating intractable rheumatism, and has advantages of quick result, short treatment period, high cure rate and low cost.