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815 results about "PANAX NOTOGINSENG ROOT" patented technology

Panax notoginseng is a species of the genus Panax, and it is commonly referred to in English as Chinese ginseng or notoginseng. In Chinese it is called tiánqī (田七), tienchi ginseng, sānqī (三七) or sanchi, three-seven root, and mountain plant.

Whitening essence suitable for sensitive skin and preparation method thereof

The invention relates to the technical field of whitening essence, and discloses whitening essence suitable for sensitive skin and a preparation method thereof.The whitening essence suitable for sensitive skin is prepared from, by mass, 2%-3% of prinsepia utilis royle oil, 1%-2% of portulaca oleracea extract, 1.5% of camellia yunnanensis flower extract, 0.5% of panax notoginseng root extract, 3% or less of nicotinamide, 1% or less of 1, 2-propylene glycol and the balance deionized water. 1%-1.5% of 1, 2-hexanediol, 0.1%-0.3% of sodium hyaluronate and 60%-70% of deionized water. According to the whitening essence suitable for the sensitive skin and the preparation method of the whitening essence, through the synergistic combination of prinsepia utilis royle oil (barrier repair), purslane (anti-inflammatory), camellia japonica (tyrosinase inhibition) and pseudo-ginseng (microcirculation improvement), melanogenesis is inhibited through multiple channels, the sensitive skin is relieved synchronously, nicotinamide (3%) is compounded with the prinsepia utilis royle oil, and the skin whitening effect is achieved. The synergism of whitening and barrier repair is enhanced through a dual mechanism of promoting ceramide synthesis and inhibiting melanin transport, and the problems that a traditional whitening agent has different degrees of irritation, allergy phenomena such as skin redness, swelling and pain are easily caused by improper use, and a skin intolerance phenomenon exists are solved.
Owner:SHANGHAI MEIFEN BIOMEDICAL TECH CO LTD

Pseudo-ginseng seed storage method

The invention discloses a pseudo-ginseng seed storage method, relates to the technical field of seed treatment, and aims to solve the problems that pseudo-ginseng seeds are difficult to store, easy to lose vigor and severely mildew.The pseudo-ginseng seed storage method adopts a specially-made bionic microenvironment packaging unit to wrap the seeds, the inner layer of the specially-made bionic microenvironment packaging unit contains a moisture slow-release agent, and a bacteriostatic agent and active substances needed by germination can be intelligently released in a staged mode; the outer layer of the seed packaging box is a selective breathable film which integrates humidity and microbial contamination state indication functions and stress buffer characteristics, then the packaged seed is placed in an intelligent regulation and control storage cabin, and the temperature and humidity are accurately regulated and controlled by the storage cabin; gas components (such as low oxygen, high carbon dioxide or ozone) regulation and control, efficient air filtration and an intelligent monitoring and remote management system can be selected, the service life of the seeds can be remarkably prolonged, high germination rate and activity are kept, mildew is effectively inhibited, physiological after-ripening and germination are optimized, and intelligentization, standardization and refinement of seed storage management are achieved.
Owner:INST OF MEDICINAL PLANTS YUNNAN ACAD OF AGRI SCI

Method for producing notoginsenoside and ginsenoside by utilizing panax notoginseng cotyledon embryo

The invention relates to a method for producing notoginsenoside and ginsenoside by utilizing panax notoginseng cotyledon embryos, and belongs to the technical field of plant adventitious root tissue culture. The method comprises the following steps: inducing embryogenic calluses by utilizing immature zygotic embryos of panax notoginseng; proliferating the panax notoginseng embryogenic callus on a plate culture medium; s2, putting the pseudo-ginseng embryogenic callus obtained in the step S2 into a liquid culture medium, carrying out cell dispersion, and sieving by using a sieve with the aperture of 24-30 meshes; a mechanical stirring type bioreactor is filled with a liquid culture medium, and the globular embryo and the heart-shaped embryo are placed in the mechanical stirring type bioreactor to be cultured; s3, recovering the filtrate in the step S3, filtering by using a screen with the aperture of 30-80 meshes and 80-150 meshes to obtain uniform panax notoginseng embryogenic cells, and differentiating the panax notoginseng embryogenic cells in a triangular flask for the step S4; and drying the cotyledon embryo obtained in the step S4 at 45 DEG C, and grinding into powder. According to the method, large-scale generation of cotyledon embryos can be completed only in 4-6 weeks, the production process is remarkably accelerated, the method is suitable for industrial batch production requirements, and the production efficiency is high.
Owner:KUNMING INST OF BOTANY CHINESE ACAD OF SCI +1

Pseudo-ginseng MYB transcription factor gene PnMYB8 and application thereof

The invention discloses a panax notoginseng MYB transcription factor gene PnMYB8, the nucleotide sequence of the gene PnMYB8 is as shown in SEQ ID NO: 1, an MYB transcription factor is encoded, molecular biology and functional genomics related technologies prove that the PnMYB8 gene has the capability of improving fungal infection resistance of plants, the PnMYB8 gene is constructed on a plant expression vector and transferred into tobacco for overexpression, and the yield of the panax notoginseng MYB transcription factor gene PnMYB8 is improved. Experimental results show that the resistance of the transgenic tobacco overexpressed with the PnMYB8 to the tryptophan destructor (Cylindrocarpon destructor), the fusarium latericum (Fusarium latericum), the fusarium equiseti (Fusarium equiseti) and the phoma herbarum (Phoma herbarum) is obviously enhanced, and the resistance of the transgenic tobacco overexpressed with the PnMYB8 to the tryptophan destructor (Fusarium latericum) is obviously enhanced.
Owner:KUNMING UNIV OF SCI & TECH

E3 ubiquitin ligase gene ulA and application thereof

The invention discloses an E3 ubiquitin ligase gene ulA, the nucleotide sequence of which is shown as SEQ ID NO: 1. The gene is knocked out from fusarium oxysporum by using a homologous recombination method to obtain a mutant strain ulA; compared with a wild strain, the mutant hulA has the advantages that the spore yield is reduced, the spore germination is delayed, the response capability to various abiotic stresses is reduced, the pathogenicity to panax notoginseng plants is reduced, and the sensitivity to six bactericides is increased, and experimental results show that the gene plays an important role in pathogenicity, drug resistance and the like of fusarium oxysporum. The gene can be used as a target gene for developing an anti-fusarium oxysporum preparation.
Owner:KUNMING UNIV OF SCI & TECH

Pseudo-ginseng flower maturity detection method based on improved YOLOv11 model

The invention discloses a pseudo-ginseng flower maturity detection method based on an improved YOLOv11 model, belongs to the field of agricultural intelligent detection and deep learning application, and relates to deep learning algorithm improvement with YOLOv11 as a baseline model, mainly to optimize and enhance three aspects of backbone network replacement, neck network optimization and loss function improvement. On the premise of slightly increasing the complexity of the model, the detection speed is kept to adapt to edge equipment, and the real-time operation requirement of the picking robot is met. A core detection method is provided for intelligent picking of the panax notoginseng flowers, the detection technology blank of small-target and easily-confused growth stages in a complex field environment is filled, and the method has engineering application value for promoting automatic upgrading of the panax notoginseng industry.
Owner:KUNMING UNIV OF SCI & TECH

Preparation method, use, and quality detection method of panax notoginseng-bletilla striata oral liquid

A preparation method, a use, and a quality detection method of a Panax notoginseng-Bletilla striata oral liquid are provided. The preparation method is simple and close to the traditional Chinese medicine preparation technology. An oral liquid solution finally prepared is clear, has a high viscosity, and exhibits better efficacy than the primary drug. In the present disclosure, the prepared Panax notoginseng-Bletilla striata oral liquid is used for the first time in preparation of an antialcoholic and hepatoprotective product. Research results show that the oral liquid can enhance the oxidation resistance of endogenous antioxidase such as glutathione (GSH) to some degree, inhibit an impact of free radical-mediated lipid peroxidation on a liver injury, and exhibit a prominent antialcoholic and hepatoprotective effect for drunk mice. The quality and efficacy of an oral liquid can be monitored scientifically by the quality detection method.
Owner:BEIJING VVHEALTH TECHNOLOGY CO LTD

Panax notoginseng bHLH transcription factor gene PnbHLH2 and application thereof

The invention discloses a pseudo-ginseng bHLH transcription factor gene PnbHLH2, the nucleotide sequence of the pseudo-ginseng bHLH transcription factor gene PnbHLH2 is as shown in SEQ ID NO: 1, a bHLH transcription factor is encoded, molecular biology and functional genomics related technologies prove that the PnbHLH2 gene has the capability of improving fungal infection resistance of plants, the PnbHLH2 gene is constructed on a plant expression vector and transferred into tobacco for overexpression, and the yield of the pseudo-ginseng bHLH transcription factor gene PnbHLH2 is improved. Experimental results show that the resistance of the transgenic tobacco overexpressed with the PnbHLH2 to fusarium latericum, fusarium moniliforme, humicola fucoatra and cylindrocarpon destructor is obviously enhanced, and the resistance of the transgenic tobacco overexpressed with the PnbHLH2 to the fusarium latericum, the fusarium moniliforme, the humicola fucoatra and the cylindrocarpon destructor is obviously enhanced. The transgenic tobacco overexpressed with the PnbHLH2 has the advantages that the resistance of the transgenic tobacco overexpressed with the PnbHLH2 to the fusarium latericum, the fusarium moniliforme, the fusarium moniliforme and the cylindrocarpon destructor is obviously improved;
Owner:KUNMING UNIV OF SCI & TECH

Application of plant-derived extracellular vesicles in preparation of product for preventing and treating photoaging and topical application composition

The invention discloses application of plant-derived extracellular vesicles in preparation of a product for preventing and treating photoaging and a topical application composition. Pseudo-ginseng is used as a raw material for extraction and purification of plant-derived extracellular vesicles, and results show that the pseudo-ginseng-derived extracellular vesicles can significantly treat or improve photoaging. The invention explores the practical application of the fresh pseudo-ginseng extracellular vesicles based on the traditional theory of traditional Chinese medicine, and clarifies the molecular mechanism of the pseudo-ginseng extracellular vesicles. In a word, the extracellular vesicles derived from pseudo-ginseng have a wide application prospect in treatment of skin aging.
Owner:GUANGDONG MODERN HANFANG TECH CO LTD

Modified pseudo-ginseng exosome as well as intestinal conditioning gel composition and application thereof

The invention relates to the technical field of functional food and biological medicine, in particular to a modified pseudo-ginseng exosome and an intestinal conditioning gel composition and application thereof. According to the gel beverage, an exosome derived from panax notoginseng callus cultured in a laboratory is used as a core active component, is modified through phosphatidylserine-aminated pectin-genipin and is embedded into a hydrogel matrix composed of carboxymethyl chitosan and sodium alginate, so that the exosome is protected from being degraded in the stomach, and the activity of the exosome in the stomach is improved. The exosome can be effectively released under the intestinal pH and flora environment, so that the targeted delivery of the intestinal tract is realized, and the preparation method is suitable for improving the intestinal inflammation and maintaining the intestinal health. The invention can effectively solve the technical problems of uncontrollable raw material quality and safety, low oral delivery stability and active ingredient availability and poor medication compliance of the existing plant exosome.
Owner:JIANGSU JICUI FUNCTIONAL MATERIALS RES INST CO LTD

Water-saving greenhouse for planting organic pseudo-ginseng

The utility model provides a water-saving greenhouse for planting organic pseudo-ginseng. The water-saving greenhouse for planting the organic pseudo-ginseng comprises a framework pipeline; the transparent plastic shed cloth is arranged on the framework pipeline; the plurality of spray heads are all arranged on the framework pipeline; the multiple first anchor rods are all arranged at the bottom of the framework pipeline; the two rainwater collecting mechanisms are both arranged on the framework pipeline, and the two rainwater collecting mechanisms are used for collecting rainwater; and the two filtering mechanisms are arranged on the two rainwater collecting mechanisms correspondingly, and the two filtering mechanisms are used for filtering impurities in rainwater. The water-saving greenhouse for planting the organic panax notoginseng has the advantages of having the functions of rainwater collection and auxiliary irrigation, and being convenient to operate and even in irrigation.
Owner:WENSHAN ZANQI TECH CO LTD

Pseudo-ginseng stem and leaf rare ginsenoside as well as preparation method and application thereof

The invention discloses radix notoginseng stem and leaf rare ginsenoside as well as a preparation method and application thereof, and belongs to the technical field of ginsenoside. The radix notoginseng stem and leaf rare ginsenoside comprises Rk3, Rh4, S-Rg3, R-Rg3, Rk1 and Rg5. The radix notoginseng stem and leaf rare ginsenoside can be used for preparing radix notoginseng stem and leaf rare ginsenoside. The preparation method comprises the following steps: mixing the pseudo-ginseng stem and leaf extract with an acetic acid aqueous solution, reacting at 105-120 DEG C for 10-40 minutes, and drying; in the preparation process, macroporous resin purification is not carried out. According to the scheme, part of chemical substances in the panax notoginseng stem and leaf extract can be rapidly converted at a low temperature, new active substances Rh4, S-Rg3, R-Rg3, Rk1 and Rg5 with high purity are obtained at the same time, and the obtained panax notoginseng stem and leaf rare ginsenoside can effectively inhibit propionibacterium acnes, burkholderia cepacia and malassezia furfur.
Owner:SHENZHEN INSTITUTE FOR DRUG CONTROL (SHENZHEN TESTING CENTER OF MEDICAL DEVICES)

Automatic seedling raising device for soilless culture

The utility model is applicable to the technical field of pseudo-ginseng cultivation, and provides a soilless culture automatic seedling raising device which comprises a cultivation box used for cultivating pseudo-ginseng seedlings, a plurality of liquid collecting boxes used for containing soilless culture nutrient solutions are arranged in the cultivation box, detachable seedling raising plates are arranged in the liquid collecting boxes, and the detachable seedling raising plates are connected with the liquid collecting boxes. A plurality of seedling holes are formed in the seedling raising plate; the liquid injection pipe is fixedly communicated with one side of the liquid collection box and is used for injecting a nutrient solution; and the liquid storage box is arranged at the top of the cultivation box and is used for storing a nutrient solution required by seedling culture. According to the automatic seedling raising device for soilless culture, the soilless culture mode is adopted, the device gets rid of limitation of soil quality, a more ideal growth environment is provided for panax notoginseng, and therefore the yield and quality are improved.
Owner:WENSHAN YUCAI PANAX NOTOGINSENG PLANTING CO LTD +1

Navigation method of intelligent pseudo-ginseng harvester based on LSTM and GNSS / INS multi-mode fusion

The invention discloses a navigation method of an intelligent pseudo-ginseng harvester based on LSTM and GNSS / INS multi-modal fusion, which comprises the following steps: firstly, acquiring multi-modal data of the harvester through a GNSS receiver and an INS inertial measurement unit, and performing timestamp alignment and noise suppression preprocessing on the multi-modal data; then, a GNSS / INS data fusion model is constructed, preliminary data fusion is realized through a Kalman filtering algorithm, and the positioning precision is improved; meanwhile, a long short-term memory network (LSTM) model is introduced, during the interruption period of GNSS signals, historical INS and GNSS data are utilized to predict GNSS pseudo position increment, pseudo GNSS position information is generated, and the pseudo GNSS position information and INS resolving data are fused again; and finally, in combination with navigation information fused by a Kalman filtering algorithm, realizing accurate positioning of the pseudo-ginseng harvester. The method can effectively improve the precision and robustness of a navigation system, and is suitable for efficient operation of the pseudo-ginseng combine harvester in complex environments of hills and mountains.
Owner:KUNMING UNIV OF SCI & TECH

A pharmaceutical composition containing fucoidan for preventing and treating chronic atrophic gastritis

The invention discloses a pharmaceutical composition for preventing and treating chronic atrophic gastritis. The pharmaceutical composition is prepared from the following raw materials in the following weight ratio: 14-18 parts of peach kernel, 10-14 parts of Chuanxiong rhizome, 8-12 parts of Panax notoginseng, 6-10 parts of safflower, 20-28 parts of kelp, 10-14 parts of selfheal, 15-25 parts of codonopsis pilosula, 10-14 parts of atractylodes macrocephala, 12-16 parts of fructus aurantii, 8-12 parts of amomum villosum, 12-16 parts of bupleurum, 10-18 parts of citron, and 5-10 parts of fucoidan. The pharmaceutical composition is used to treat chronic atrophic gastritis of gastric collateral blood stasis type by promoting blood circulation and removing blood stasis, unblocking meridians and relieving pain, eliminating phlegm, softening and dispersing nodules, invigorating qi and promoting qi circulation, and soothing the liver and harmonizing the stomach. The invention also discloses a preparation method of the pharmaceutical composition.
Owner:THIRD INSTITUTE OF OCEANOGRAPHY STATE OCEANI C ADMINISTRATION

Composition for relieving anxiety and improving sleep as well as preparation method and application of composition

PendingCN121040619AFood shapingFood technologyBlack chokeberry
The invention relates to the technical field of food, in particular to a composition for relieving anxiety and improving sleep and a preparation method and application thereof, and the composition is composed of jujuboside, anthocyanin, gamma-aminobutyric acid and ginsenoside Rb1. The jujuboside is derived from spina date seeds, the anthocyanin is derived from at least one of lycium ruthenicum, blueberry purple epidermis, aronia melanocarpa and mulberries, and the ginsenoside Rb1 is derived from at least one of ginseng roots, ginseng stems and leaves, ginseng flowers, panax notoginseng roots, panax notoginseng stems and leaves, panax notoginseng flowers, panax notoginseng fibrous roots and American ginseng. According to the invention, a plurality of components are synergistic, the efficacy is comprehensive and the pertinence is strong, the effective components are not simply mixed, but form a highly synergistic action system, and the efficacy covers multiple dimensions of improving sleep, relieving anxiety and improving the overall state.
Owner:HANGZHOU QIREN BIOTECHNOLOGY CO LTD +1

Application of traditional Chinese medicine composition in preparation of anti-hepatoma drugs

The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to application of a traditional Chinese medicine composition in preparation of anti-hepatoma medicines. The traditional Chinese medicine composition comprises red ginseng, ox horn tip, musk, borneol, safflower, bezoar, radix aconiti lateralis praeparata slice, venenum bufonis, pseudo-ginseng, benzoin and pearl. Experimental results show that the traditional Chinese medicine composition can induce apoptosis and necrosis of liver cancer cells and inhibit proliferation of the liver cancer cells; and liver cancer cells are retarded to be in a G1 cell cycle. Therefore, the invention provides a new therapeutic drug for clinical treatment of liver cancer, and the raw materials are natural medicinal materials, have wide sources and have good application prospects.
Owner:GUANGDONG LIFESTRONG PHARMACY CO LTD

Application of camphene in promoting seed germination and seedling growth of Panax notoginseng

The invention relates to the technical field of Panax notoginseng planting, and in particular to the application of camphene in promoting the germination of Panax notoginseng seeds and the growth of seedlings. The invention can increase the seed germination rate of Panax notoginseng by fumigating the soil for planting Panax notoginseng with camphene, a volatile substance, and then planting Panax notoginseng seeds on the soil fumigated with camphene, thereby helping the Panax notoginseng seedlings to increase biomass, increasing the above-ground development of Panax notoginseng, promoting the extension of the roots of Panax notoginseng, facilitating the absorption of soil nutrients by Panax notoginseng, and having a significant promoting effect on the germination of Panax notoginseng seeds and the growth of seedlings.
Owner:INST OF MEDICINAL PLANTS YUNNAN ACAD OF AGRI SCI

Preparation method and application of tannic acid and panax notoginseng total saponin composite drug-loaded multifunctional hydrogel

The invention provides a preparation method and application of tannic acid and panax notoginseng total saponins composite drug-loaded multifunctional hydrogel, and relates to the technical field of biomedical materials.Chitosan, one of the components of the hydrogel, is subjected to carboxymethylation modification to form carboxymethyl chitosan, the carboxymethyl chitosan and aldehyde-modified xanthan gum are subjected to a Schiff base reaction, and the hydrogel is prepared into the multifunctional drug-loaded tannic acid and panax notoginseng total saponins composite drug-loaded multifunctional hydrogel. Meanwhile, tannic acid and panax notoginseng saponins are loaded, and the composite hydrogel is obtained. The hydrogel loaded with the tannic acid and the panax notoginseng saponins, provided by the invention, carries the tannic acid and the panax notoginseng saponins as active substances, can keep the activity of the medicine for a long time, and has good injectability, self-healing property and wound exudate absorption property, the tannic acid can inhibit inflammatory response and reduce the generation and release of inflammatory factors, and the hydrogel loaded with the tannic acid and the panax notoginseng saponins can be used for treating wound exudate. The tannic acid has a wide antibacterial property, such as IL-1beta, IL-6, TNF-alpha and the like, and can inhibit the growth and reproduction of various bacteria, including common pathogenic bacteria such as staphylococcus aureus, escherichia coli and the like.
Owner:UNIV OF JINAN

Traditional Chinese medicine fermented disaccharide encapsulated nano anti-dandruff, hair-growing and oil-controlling shampoo and preparation method thereof

The invention provides traditional Chinese medicine fermented disaccharide encapsulated nano anti-dandruff, hair-growing and oil-controlling shampoo and a preparation method, and relates to the field of daily chemical products, and the shampoo comprises the following components: a compound fermentation product, lactobacillus crispatus, lactobacillus plantarum, a disaccharide activity protection system, a basic component and a nano oil-controlling component; the compound leavening is prepared from cacumen biotae, radix polygoni multiflori, radix ginseng, fructus cnidii and orchid; the disaccharide activity protection system comprises maltotetraose and trehalose; the disaccharide activity protection system wraps a fermented material formed by fermenting the compound fermentation product, the lactobacillus crispatus and the lactobacillus plantarum to form a disaccharide glassy state layer; the nano oil control component is prepared from calamine powder and chitosan-sodium alginate; the basic component is prepared from tea bran, radix sophorae flavescentis, herba ecliptae, radix notoginseng, fructus ligustri lucidi, tea saponin microcapsules and tremella polysaccharide. According to the invention, through fermentation conversion of the orchid, disaccharide glassy state protection and slow release of the nano calamine, activity enhancement, stable retention and accurate release are realized, and the effects of removing dandruff, relieving itching, controlling oil and growing hair are achieved.
Owner:HENGYANG AIMINKANG BIOTECHNOLOGY CO LTD

A traditional Chinese medicine composition for clearing away heat, removing blood stasis, stopping bleeding and regulating menstruation and its preparation method

ActiveCN117582468BOrganic active ingredientsSexual disorderAucubinExcessive menstrual flow
The present invention provides a traditional Chinese medicine composition for clearing heat, removing blood stasis, stopping bleeding and regulating menstruation, and a preparation method thereof, relating to the technical field of traditional Chinese medicine. The traditional Chinese medicine composition of the present invention comprises the following components: catalpol, aucubin, β-sitosterol, emodin, chrysophanol, sanguisorba officinalis extract, Panax notoginseng saponins, septamine, cuttlefish scaly, rubiacin, typhaneuroside, and p-coumaric acid; the components synergistically work together to significantly reduce plasma prothrombin time and plasma recalcification time, and significantly reduce the whole blood viscosity, plasma viscosity, and hematocrit of rats with blood stasis syndrome. The traditional Chinese medicine composition of the present invention is used in the preparation of drugs for menstrual disorders or menstrual bleeding and metrorrhagia, and has a significant therapeutic effect on irregular menstruation, excessive menstrual bleeding, or metrorrhagia.
Owner:JIANGXI POZIN PHARMA

Traditional Chinese medicine composition for treating fatty liver diseases related to metabolic dysfunction and application of traditional Chinese medicine composition

The invention discloses a traditional Chinese medicine composition for treating fatty liver diseases related to metabolic dysfunction. The traditional Chinese medicine composition is prepared from the following raw material medicines: Qu fructus aurantii, lotus leaves, semen cassiae, gynostemma pentaphylla, rhizoma alismatis, rhodiola rosea, radix salviae miltiorrhizae, pseudo-ginseng and rhizoma atractylodis macrocephalae. The traditional Chinese medicine composition and the traditional Chinese medicine compound preparation disclosed by the invention can improve the blood sugar and blood fat levels of fatty liver diseases related to metabolic dysfunction and improve the metabolic level, are remarkable in clinical curative effect, improve the living quality of patients, have the effects of regulating qi, soothing the liver, tonifying the spleen and removing stasis, slow down liver fibrosis by improving blood sugar and blood fat metabolism, and are quick in curative effect and low in price.
Owner:THE FIRST AFFILIATED HOSPITAL OF ZHEJIANG CHINESE MEDICAL UNIVERSITY

Arabinose glycosyl transferase and application of arabinose glycosyl transferase in preparation of panax japonicus saponin IV

The invention discloses arabinose glycosyl transferase PnUGT73B4 and application thereof to preparation of panax japonicus saponin IV, the amino acid sequence of the arabinose glycosyl transferase is shown as SEQ ID NO: 1, under the catalysis of the arabinose glycosyl transferase PnUGT73B4, UDP-arabinose is added to a glucuronic acid group on the C3 site of panax japonicus saponin IVa, and the panax japonicus saponin IV is generated; according to the method, the requirement for raw material plants can be reduced, agricultural land is saved, the product is single, preparation of the panax japonicus saponin IV is facilitated, the biosynthesis route of oleanane type triterpenoid saponin is analyzed, and a breakthrough solution is provided for biosynthesis of the panax japonicus saponin IV.
Owner:KUNMING UNIV OF SCI & TECH

Traditional Chinese medicine composition for resisting aging of stem cells as well as preparation method and application of traditional Chinese medicine composition

The invention relates to the technical field of traditional Chinese medicines, and discloses a traditional Chinese medicine composition for resisting stem cell aging as well as a preparation method and application thereof. The traditional Chinese medicine composition comprises 30 parts of astragalus membranaceus, 15 parts of fructus psoraleae, 15 parts of codonopsis pilosula, 15 parts of roasted rhizoma atractylodis macrocephalae, 10 parts of eucommia ulmoides, 15 parts of herba epimedii, 15 parts of glossy privet fruit, 15 parts of Chinese yam, 15 parts of radix paeoniae alba, 15 parts of gynostemma pentaphylla, 6 parts of pseudo-ginseng powder, 20 parts of sculellaria barbata, 15 parts of poria cocos, 10 parts of radix bupleuri, 30 parts of raw oyster shell, 15 parts of vinegar turtle shell, 15 parts of rhizoma pinellinae praeparata, 15 parts of eclipta, 6 parts of pericarpium citri reticulatae and 6 parts of liquorice. The preparation method comprises water extraction and concentration to prepare powder. The composition can be used for inhibiting the aging of the mesenchymal stem cells and improving the cell activity, and can be combined with the mesenchymal stem cells to treat degenerative bone diseases including osteoporosis and femoral head necrosis.
Owner:THE SECOND AFFILIATED HOSPITAL OF GUANGXI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE

Probiotic composition for improving immunity and preparation method thereof

The invention provides a probiotic composition for improving immunity and a preparation method thereof, and belongs to the technical field of probiotics. The preparation method comprises the following steps: fermenting selenium-enriched nostoc sphaeroides through selenium-enriched saccharomycetes to extract selenium-enriched nostoc sphaeroides polysaccharide and selenium-enriched nostoc sphaeroides protein peptide, mixing with traditional Chinese medicine polysaccharide obtained by extracting astragalus membranaceus, rhodiola rosea, codonopsis pilosula and pseudo-ginseng, and reacting with ferric salt to prepare a polysaccharide-Fe / selenium compound; solid residues are mixed and fermented, and active protein peptide is prepared from the solid residues and selenium-rich nostoc sphaeroides protein peptide; the probiotic composition capable of improving immunity is prepared by extracting a polysaccharide-Fe / selenium compound and a polysaccharide-Fe / selenium compound through an organic solvent, extracting a permeate through an organic solvent to obtain an active component, collecting a bacterial liquid, mixing and embedding the bacterial liquid in the polysaccharide-Fe / selenium compound and sodium alginate, and uniformly mixing the bacterial liquid with the active protein peptide, the active component, taurine and ginsenoside Rg3, so that the probiotic composition capable of improving immunity can play good anti-inflammatory, anti-oxidation, immunoregulation, anti-tumor, anti-virus and other roles, and has a good application prospect. Wide application prospects are realized.
Owner:余昭军

Multi-input multi-output fuzzy neural network control method and system for panax notoginseng planting greenhouse

The invention discloses a multi-input multi-output fuzzy neural network control method and system for a pseudo-ginseng planting greenhouse, and the method comprises the steps: obtaining original parameters including greenhouse temperature, humidity, illumination, water and fertilizer concentration, pseudo-ginseng growth state and water flow velocity, and carrying out the standardization of the original parameters, and obtaining input parameters; inputting the parameter into a three-layer back propagation neural network pre-training model, and outputting initial adjustment coefficients of six control quantities such as the opening degree of the sunshade; constructing a fuzzy rule base based on a parameter coupling scene, inputting a preliminary adjustment coefficient to obtain a fuzzy output quantity, and performing defuzzification through a gravity center method to obtain a corrected adjustment coefficient; a control instruction is calculated in combination with an equipment rated range, and closed-loop control is realized through dynamic adjustment. The system automatically operates through a multi-parameter acquisition module, an equipment control output module and the like. The application breaks through the traditional single-input single-output limitation, reduces the parameter fluctuation by more than 50%, adapts to the whole growth cycle of pseudo-ginseng, improves the utilization rate and yield of water and fertilizer, reduces the labor cost, and has remarkable economic benefits.
Owner:KUNMING UNIV OF SCI & TECH

Method for high-yield production of rare saponin Rg3 through gene editing of panax notoginseng adventitious root saponin synthesis pathway

The invention discloses a method for high-yield production of rare saponin Rg3 through gene editing of a panax notoginseng adventitious root saponin synthesis pathway, which comprises the following steps: 1) inputting a gene CYP716A53V2 into an online tool CRISPR to find a series of potential Cas9 target sites, and carrying out random selection; (2) respectively designing downstream primers according to different selected Cas9 target sites, and carrying out PCR (Polymerase Chain Reaction) amplification by using a U6p.4-F primer as an upstream primer to respectively obtain different sgRNA sequences; (3) respectively connecting the sgRNA-n with a linearized pP1C.4 carrier, so as to obtain a recombinant plasmid; 4) respectively transforming the recombinant plasmids into agrobacterium rhizogenes, and culturing to obtain different recombinant bacterial liquids; and (5) respectively putting the pseudo-ginseng adventitious roots into different positive recombinant bacteria solutions, carrying out vacuum infection, and screening out the transgenic pseudo-ginseng adventitious roots with high Rg3 content. The method has the advantages of controllable steps, accurate regulation and control, greenness, environmental protection and high yield of saponin Rg3.
Owner:TIANJIN UNIV

Pseudo-ginseng flower maturity detection method based on improved RT-DETR model

The invention discloses a pseudo-ginseng flower maturity detection method based on an improved RT-DETR model, and belongs to the field of agricultural intelligent detection and deep learning application, the pseudo-ginseng flower maturity detection method is an improvement of a deep learning algorithm taking RT-DETR as a baseline model, and mainly performs optimization and enhancement on three aspects of backbone network replacement, neck network optimization and AIFI module partial replacement. On the premise of ensuring the detection speed, the lightweight detection model with lower complexity and higher detection precision is successfully realized. The model provides a core detection method for intelligent picking of panax notoginseng flowers, fills the blank of small-target and easily-confused growth stage detection technologies in a complex field environment, has important engineering application value, and promotes automatic upgrading of the panax notoginseng industry.
Owner:KUNMING UNIV OF SCI & TECH

A Chinese medicine composition for treating hyperlipidemia and its preparation method and application

The present invention provides a Chinese medicine composition for treating hyperlipidemia, and a preparation method and application thereof. The Chinese medicine composition, by weight, comprises: 4-12 parts of hawthorn, 8-12 parts of salvia miltiorrhiza, 4-12 parts of panax notoginseng and 4-12 parts of pearly buds. The preparation method comprises: (1) crushing the Chinese medicinal materials hawthorn, salvia miltiorrhiza, panax notoginseng and pearly buds to obtain a powder; (2) using an ethanol aqueous solution as an extraction solvent to extract the powder, and concentrating the obtained extract to obtain a compound extract of the Chinese medicine composition. Although pearly buds have no effect on lowering blood lipids, when it is used in combination with hawthorn, salvia miltiorrhiza and panax notoginseng, it can improve the blood lipid lowering effect of the hawthorn, salvia miltiorrhiza and panax notoginseng composition.
Owner:ZHUHAI HENGQIN AOYE HEALTH TECH CO LTD

Preparation method and equipment of freckle-removing mask

The invention discloses a freckle-removing mask preparation method and equipment, and relates to the technical field of beauty and skincare, the freckle-removing mask preparation method comprises the following steps: S1, selecting and purchasing: selecting and purchasing high-quality formula raw materials; s2, inspection: inspecting the purchased raw materials; s3, pretreatment: washing part of the Chinese herbal medicine raw materials with clear water, and drying the Chinese herbal medicine raw materials; s4, pre-processing: crushing and grinding the prepared raw materials, and screening and filtering to remove impurities; the facial mask is prepared from ligusticum, radix angelicae, radix asparagi, astragalus membranaceus, bighead atractylodes rhizome, silkworm larva, bletilla striata, radix paeoniae alba, poria cocos, salvia miltiorrhiza, ampelopsis japonica, tribulus terrestris, pseudo-ginseng, rose, ginseng, honeysuckle, pearl and other blood-activating and repairing components, so that the effect of eliminating laser spots and heavy metal residual spots is improved, and meanwhile, the whitening degree and the skin glossiness are improved; the ductility, the moistening property and the permeability are improved, the stickiness and the greasiness are reduced, the moisturizing and water locking durability is improved through moisturizing factors of various components, and the spot fading effect is improved.
Owner:GUANGXI HUIHUATANG AGRICULTURAL CO LTD