236 results about "Microcirculation" patented technology

The invention discloses a pressure injury risk early warning method and equipment, and relates to the technical field of medical monitoring instruments. The pressure sensor array layout can be self-adaptive to the body shape of a patient, a key osseous process part is covered, no monitoring dead angle is ensured, a temperature compensation mechanism is built in, environmental interference is reduced, the measurement precision is improved, an abnormal pressure threshold value can be dynamically set based on individual medical record data, data verification is performed before early warning is triggered, false alarm is avoided, and the array structure is light, thin and flexible. The mask is comfortable to fit skin, supports long-term wearing and is easy to disinfect and maintain; environment temperature and humidity parameters and pressure data are subjected to fusion analysis, the influence of a high-temperature and high-humidity environment on skin microcirculation can be recognized, the risk of pressure sores can be evaluated in an auxiliary mode, a calibration algorithm is built in a sensor, environment fluctuation interference is reduced, and data reliability is ensured; and the early warning unit comprises sound-light alarm equipment which supports a multi-stage alarm mode and is used for triggering an early warning signal and pushing information when the risk index exceeds a threshold value, so that the early warning timeliness is ensured and the false alarm risk is reduced.

The invention discloses a multi-mode synchronous monitoring method and system based on traditional Chinese medicine pulse conditions and microcirculation, and relates to the technical field of traditional Chinese medicine intelligent diagnosis. A pulse position coordinate set is generated by combining a preset space mapping relation; a pulse pressure signal and a microcirculation blood flow image are synchronously acquired; frequency domain transformation is performed on the pulse pressure signal and a pathological risk probability L is calculated; a comprehensive node feature vector is constructed to form a graph structure; a pathology mode recognition result is output by matching a pathology sub-atlas template library, dynamic correlation analysis of traditional Chinese medicine pulse conditions and microcirculation is achieved, and the technical bottlenecks that traditional pulse diagnosis is high in subjectivity, multi-mode asynchronous and difficult in pathology quantification are broken through.

The invention provides a real-time processing method for endoscopic image blood vessel enhancement and microcirculation evaluation, which comprises the following steps of: processing an original endoscopic image, and locally enhancing a brightness channel through a contrast-limited adaptive histogram equalization technology; self-adaptive frequency domain-space domain decomposition is realized based on local texture complexity analysis; performing multi-scale Hessian matrix blood vessel detection on the low-frequency component; applying a directional Gabor filter bank to the high-frequency component; spatial-temporal feature fusion is realized through multi-resolution pyramid optical flow calculation; synchronously completing blood vessel probability prediction, blood vessel diameter estimation and blood flow direction prediction by using a lightweight multi-task deep learning network; the blood flow velocity is analyzed and calculated based on a speckle mode, the perfusion density is subjected to accelerated statistics through an integrogram, and vascular morphological parameters are extracted by adopting an improved skeleton algorithm. According to the invention, an enhanced blood vessel visualization effect and a real-time microcirculation quantitative evaluation function can be provided, and the overall improvement of the endoscope image processing quality and efficiency is realized.

The invention discloses a bedside skin flap blood flow monitoring and early warning device and computing equipment, and the device comprises a skin flap tissue perfusion monitoring module which comprises a probe housing, a microcirculation blood flow velocity sensor, a tissue oxygenation degree sensor and a flexible connecting arm; the data acquisition and transmission module is used for receiving the blood flow velocity data and the oxygenation degree data through a data line and carrying out analog-to-digital conversion and data packaging; the central processing unit comprises a data storage module, a data analysis module and an early warning module; the data analysis module comprises a baseline establishment sub-module, an anomaly detection sub-module and a trend prediction sub-module; and the early warning module is used for displaying a red alarm through a bedside display screen and sending a short message alarm containing the patient name, the bed number, the early warning type and the severity information to a medical staff mobile terminal through the wireless notification module. According to the invention, the abnormal condition of skin flap blood perfusion can be found and predicted in time, and the workload of medical staff is reduced.

The invention discloses a wound healing state evaluation method and system based on artificial intelligence, and belongs to the field of wound healing evaluation. The method comprises the following steps: integrating medical record data and wound physiological parameters, and extracting relevance between a medication history and an infection type to form a multi-dimensional pathological factor; hemoglobin oxygenation, blood flow and metabolic heat are subjected to cross-period correlation analysis to construct dynamic physiological time-space information, pathological factors and the physiological time-space information are fused into a heterogeneous graph, nodes comprise drug intensity quantized values, infection risk levels and microcirculation fluctuation values, and edge weights are determined by the time sequence matching degree of drug doses and blood flow changes; based on the node weight and the edge association relationship, the treatment time and the physiological parameter acquisition period are aligned to generate a spatio-temporal evolution matrix, the spatial distribution of the infection risk level and the metabolic heat value characteristics are combined, the dynamic association of the drug action intensity and the microcirculation fluctuation is analyzed, and wound healing evaluation information is generated. The accuracy of wound healing state evaluation can be improved.

The invention provides a preparation method of medicinal liquor and application of the medicinal liquor in preparation of products for preventing cardiovascular and cerebrovascular diseases and improving microcirculation, and belongs to the technical field of pharmaceutical compositions. The preparation method comprises the following steps: (1) crushing; (2) extracting; (3) standing and separating; and (4) freezing and filtering to obtain the medicinal liquor. In the preparation process, traditional Chinese medicine components are extracted through the steps of batch crushing, mixed extraction, standing, freezing and separation of supernate and suspension in different separation modes to obtain the medicinal liquor, and the medicinal liquor is high in active ingredient activity, good in stability, free of layering after being placed for a long time, free of sediment and free of toxic and side effects. And the traditional Chinese medicine composition has obvious effects on preventing cardiovascular and cerebrovascular diseases and improving microcirculation.

The invention provides eye protection liquid for improving eye microcirculation and a preparation method thereof, and belongs to the technical field of medical configuration products. The composition comprises the following components: surface-modified magnetic nanoparticles, a calendula extract, a fermented dogwood extract, xanthophyll, taurine, sodium hyaluronate, hydrolyzed sodium hyaluronate, soya bean lecithin, borneol and fermented vegetable oil. The efficiency of active ingredients is improved through a double-fermentation technology, magnetic targeting and multi-channel compounding are combined, and the preparation method has remarkable advantages in the field of improving periorbital microcirculation. The traditional Chinese medicine composition has an obvious relieving effect on asthenopia and dry skin around eyes; the components of the eye microcirculation eye protection liquid are mild, and adverse reactions such as allergy cannot be caused.

The invention discloses a hematopoietic preparation for treating androgenetic alopecia and a preparation method of the hematopoietic preparation. The hematopoietic preparation is prepared from 5-30 parts of radix polygoni multiflori preparata, 5-30 parts of wine ligustrum lucidum ait, 5-30 parts of mulberry, 5-30 parts of eclipta, 5-30 parts of radix paeoniae alba, 5-30 parts of astragalus membranaceus and 5-30 parts of rhizoma cibotii. The medicine composition and the specific dosage are obtained through a large number of experimental screening and clinical medication experience screening. The whole formula takes tonifying liver and kidney and benefiting essence and blood as the monarch, and takes tonifying spleen and qi and removing heat to cool blood as the minister and assistant, based on the traditional Chinese medicine theory that essence is stored in kidney and is warmed on hair, by inhibiting DHT generation, resisting hair follicle apoptosis and improving scalp microcirculation, the traditional Chinese medicine composition has the remarkable effect of treating androgenetic alopecia, is weak in toxic and side effects, and can be prepared into various clinical dosage forms.

The invention discloses an intracranial anterior artery circulation functional evaluation method and device, computer equipment and a storage medium, and relates to the field of vascular function evaluation, and the method comprises the steps: based on an intracranial angiography image and near-end pressure data, carrying out the five working processes of data input, blood vessel segmentation and segmentation, boundary condition calculation, hemodynamic simulation and functional parameter calculation; according to the method, functional parameters verified in the coronary artery field are migrated to intracranial blood vessel evaluation without additional equipment, the clinical problem that traditional morphological evaluation is not matched with functionality is solved, individualized function quantification is achieved by integrating blood vessel morphological characteristics and hemodynamic simulation, and the method is suitable for being applied to intracranial blood vessel evaluation. According to the method, an objective basis is provided for cerebrovascular disease diagnosis and treatment, the intracranial vascular disease is promoted to be converted from anatomy orientation to function orientation, the clinical decision accuracy is remarkably improved, popularization and application of functional evaluation in the field of neural intervention are accelerated, and construction of a cerebrovascular disease accurate diagnosis and treatment system is assisted.

The invention relates to the technical field of intraoperative intelligent monitoring, and particularly discloses a spinal canal debonding method and system for real-time state evaluation, and the method comprises the steps: collecting neural structure microcirculation blood flow data in real time through integrating a micro-sensing unit at a working end part of a surgical instrument, and extracting blood flow oscillation frequency and capillary hematocrit parameters; performing multi-scale signal decomposition on the blood flow oscillation frequency to obtain an energy distribution parameter, and performing dynamic mode recognition on the hematocrit data to obtain a main variation characteristic value; fusing the two characteristic parameters to generate a nervous tissue vitality index; inputting the index into a pre-trained neural network for time sequence feature analysis, and outputting a graded ischemia risk early warning signal; the operation rhythm is automatically adjusted through a decision tree control mechanism based on the early warning signal, and self-adaptive regulation and control according to the state of the nervous tissue are achieved; the technical problem that the risk of neural ischemia cannot be monitored in real time in a traditional spinal canal release operation is solved, and occult nerve injury caused by asymptomatic neural ischemia can be prevented.

The invention relates to the technical field of intelligent diagnosis and treatment, and discloses an intelligent diagnosis and treatment system for dynamic risk early warning and intervention of orthopedic patients, and the system comprises a dynamic monitoring end, an intelligent grading end, a precise intervention end, a voice alarm module and a doctor's advice cooperation module. A multi-source sensor is used for continuously collecting vital signs of a patient and local microcirculation and behavior data of an affected limb in real time, and dynamic fusion analysis is carried out based on an orthopedic specialized risk model, so that early abnormal changes of deep venous thrombosis, stress injury and falling risks can be recognized in real time; the method overcomes the hysteresis quality of traditional manual intermittent evaluation and static scale, ensures the accuracy and timeliness of early warning of severe risks, and reduces clinical risks caused by untimely intervention.

The invention relates to the field of artificial intelligence medical treatment, in particular to a multi-modal feature fusion analysis system and method for gynecological face diagnosis, and aims to improve the early diagnosis precision of gynecological diseases, the system fuses multispectral images and symptom text data, and captures capillary morphology and hemodynamic parameters through a microcirculation feature extraction module; the region mapping analysis module is combined with the face region-gynecological viscera knowledge graph to generate viscera abnormality scores; the endocrine cycle modeling module constructs a dynamic model based on historical data and monitors cycle abnormity; the semantic attention fusion module fuses the symptom text and the microcirculation features by using a bidirectional cross attention mechanism to form a fusion feature vector; the knowledge reasoning feedback module is used for generating a diagnosis result and a personalized conditioning scheme based on dynamic knowledge graph multi-path reasoning, and optimizing a diagnosis and treatment path. The system overcomes the limitation of a traditional two-dimensional RGB image, effectively captures the subepidermal microcirculation state, and provides an important basis for early diagnosis of gynecological diseases.

A microcirculation reconstruction bone implant capable of generating internal stress comprises a support shell and a support inner core. The support inner core is sleeved with the support shell, and the support shell and the support inner core form a matched structure. The stent shell is located between the bone tissue and the stent inner core, and the stent shell generates elastic deformation to generate internal stress and applies the internal stress to the surrounding bone tissue when the stent is implanted and loaded; a microcirculation reconstruction passage is also loaded on the stent inner core; by adopting a mode that the stent inner core is matched with the stent shell, the stent inner core is matched with the stent shell to form an elastic effect, so that internal stress can be continuously applied to bone tissues in postoperative application to promote bone growth and integration; and a complex stress environment can be adaptively adjusted, so that the stress compatibility between the implant and a bone tissue is ensured, new intraosseous circulation is established, and the postoperative healing effect after the implant is applied is promoted.

The invention relates to the technical field of cosmetics, in particular to a composition for promoting skin microcirculation as well as a preparation method and application thereof, and the key point of the technical scheme is that the composition consists of the following components: rhizoma bletillae, motherwort, poria cocos, moutan bark, ginseng, peach blossom and lotus. According to the composition, the deep-eutectic solvent is combined with a micro-jet extraction technology, so that the extraction efficiency of active ingredients such as flavonoids is remarkably improved, and functional ingredients for resisting oxidation, resisting aging and promoting blood circulation are effectively reserved. According to the composition disclosed by the invention, the comprehensive effects of improving skin microcirculation, relieving dark skin color and delaying senescence are systematically realized by efficiently extracting active substances, activating a microcirculation core pathway and cooperating with coherent effects of a whitening and repairing mechanism.

The invention discloses a coronary artery lesion detection method based on retinal vessel marker concept perception and multi-modal fusion, and relates to the problem that in the coronary artery lesion detection technology, the existing method is difficult to effectively utilize retinal vessel markers and realize multi-modal feature fusion detection. Coronary artery lesion is a main cardiovascular disease threatening human health, and early diagnosis is of great significance. Traditional detection depends on contrast examination and has the limitations of trauma, high cost and the like. The retinal blood vessel reflects the microcirculation state of the whole body, and a new way is provided for non-invasive detection by combining clinical indexes. The invention provides a coronary artery lesion detection method based on fusion of retinal vascular marker concept perception and multi-mode. The method has the advantages that (1) markers such as blood vessel density and curvature are calculated, and retinal blood vessel morphology is quantified; and (2) image features and clinical features are fused through a cross-modal attention aggregation mechanism, so that coronary artery disease diagnosis performance is improved. The method can be used for auxiliary detection of coronary artery lesions.

The invention is suitable for the technical field of bio-photonics, and provides a capillary refilling time self-adaptive measurement system and method, and the system comprises a negative pressure adsorption module, a step release module, a modulation module, a detection module, a demodulation module, a signal processing module and a main control unit. Standardized microcirculation stimulation is realized through negative pressure adsorption and step release; adopting a frequency domain modulation and demodulation technology to obtain the phase and the amplitude of the optical signal, and inverting an absolute absorption coefficient and a reduced scattering coefficient by utilizing a frequency domain diffusion equation; and selecting an absolute absorption coefficient under equal absorption point wavelength as a blood volume index, fitting a recovery curve through a system identification model, and calculating to obtain self-adaptive capillary refilling time. According to the collaborative scheme, the problems that in the prior art, stimulation is not standard, the result is greatly influenced by skin color and temperature, and absolute parameter support is lacked are solved, and objective and accurate measurement which is high in repeatability, cross in skin color and resistant to environmental interference is achieved.

The invention relates to the technical field of medical image processing, in particular to a cardiovascular surgery patient circulation state image real-time monitoring and early warning system. Comprising a video acquisition module, an image preprocessing module, a microcirculation evaluation module, a multi-part perfusion fusion module based on differential manifold, a trend prediction and early warning module and a clinical interaction and data integration module. A local perfusion index and a pulsation stability index are extracted after preprocessing, multi-part microcirculation signals are creatively mapped to a differential manifold for characterization, time-frequency dual-channel fusion driven by Riemannian geometry and an attention weighting mechanism are integrated into a whole-body perfusion comprehensive index, modeling is carried out based on a dynamic system on the manifold, and a whole-body perfusion model is established. Early warning can be provided before the conventional blood pressure is obviously reduced, precious time is gained for clinical intervention, invasive complications are avoided through a non-invasive monitoring mode, and whole-course continuous monitoring can be achieved.

The invention relates to a dietary therapy formula for improving microcirculation of inner ears and a preparation method. Components with homology of medicine and food are selected, the black rice, the blueberries and the purple cabbages are rich in anthocyanin and beneficial to removing free radicals in cochlea and inhibiting hair cell apoptosis, the walnut kernels and the Chinese wolfberry fruits can improve blood vessel elasticity and protect auditory neurons, and the radix salviae miltiorrhizae, the hawthorn fruits and the radix puerariae can increase blood flow of inner ears, promote nutrition delivery, reduce blood viscosity and reduce vasospasm, so that the health-care food is suitable for being eaten by people. The whole component is low in sugar content, suitable for diabetics and capable of expanding the crowd. Effective components are processed into non-medicinal products, food therapy is beneficial to improving microcirculation of inner ears, relieving ear symptoms such as tinnitus and the like and delaying hearing loss, and a user can eat the food for a long time without psychological burden of medication.

The invention discloses a traditional Chinese medicine composition for treating qi deficiency and collateral arthralgia type depression. The composition is mainly prepared from the following traditional Chinese medicines in parts by weight: 25 to 400 parts of ginseng, 30 to 500 parts of cassia twig, 30 to 600 parts of radix paeoniae alba, 30 to 150 parts of radix curcumae and 30 to 150 parts of honey-fried licorice root. The composition can also comprise 20-200 parts of fresh ginger. Tests prove that the treatment effect of the composition on qi-deficiency collateral-arthralgia type depression is equivalent to or better than that of fluoxetine, the composition has remarkable treatment effects of tonifying qi and dredging collaterals while resisting depression, the symptoms of weakness, wind intolerance, gastrointestinal weakness and blood microcirculation injury of patients are effectively relieved, and the positive drug fluoxetine does not have the effects.

The application discloses a kind of solid teeth pain-relieving and inflammation-clearing traditional Chinese medicine composition, it is related to traditional Chinese medicine product technical field.The composition is composed of gypsum, raw rehmannia, coptis, talc, ocher, radix cyathulae and salvia miltiorrhiza seven raw medicinal materials, wherein gypsum, raw rehmannia are monarch drug, clear and purge stomach fire, cool blood and nourish yin;Coptis, talc are ministerial drug, clear heat and dry dampness, lead heat down;Ocher, radix cyathulae are auxiliary drug, heavy town counteract, lead fire down;Salvia miltiorrhiza is servant drug, promote blood circulation and remove blood stasis, promote tissue repair.Modern pharmacological research shows that each drug of the present party has the effects of anti-inflammatory, analgesic, antibacterial, improving microcirculation and protecting periodontal tissue etc.Clinical observation shows that the pain of most patients caused by stomach fire attacking upward, gum redness and swelling, burning pain, bleeding is significantly reduced after taking 1-2 doses, redness and swelling gradually subside.Compared with existing Chinese patent medicines, the present application is simple in prescription, low in cost, has the dual effects of rapid pain relief and long-term tooth fixation, and is especially suitable for patients with recurrent toothache and early periodontitis.

The invention belongs to the technical field of diabetic foot clinical path management, and discloses a diabetic foot patient path management method and system based on lower limb vasculopathy grading. Mapping the ulcer position to the corresponding perfusion area and the artery segment to generate ulcer space characteristics; calculating a blood supply risk score of the perfusion area and generating a space risk map by combining the blood vessel image detection data and the microcirculation detection data; then collecting time sequence data including an ulcer index, an infection index, a blood supply index and a space risk map, and predicting the progress speed and the risk level of the future ulcer course; and finally, according to the blood supply risk score and the disease course prediction result, generating an individualized path management scheme through a joint triggering rule. According to the invention, precise and dynamic management of the diabetic foot ulcer is realized, the healing rate is improved, and the recurrence rate and the medical cost are reduced.

The application relates to the technical field of medical devices, in particular to a rear-end cover sealing and waterproof structure of a microcirculation imaging device. The rear-end cover sealing and waterproof structure comprises a cylindrical shell with a rear-end opening, an inner cover and an outer cover. The inner cover is embedded into the shell from the rear-end opening of the shell and is fixedly connected with one end of an inner support of the shell. The outer edge of the inner cover is attached to the inner surface of the shell, and a groove is arranged on the outer edge of the inner cover for mounting a sealing rubber ring. A first protruding ring is arranged on the outer end surface of the inner cover. A second protruding ring and a third protruding ring are arranged on the inner end surface of the outer cover. The ring surface of the second protruding ring is attached to the inner surface of the shell, and the third protruding ring is fixedly connected with the first protruding ring through screw threads. The outer edge of the inner cover is attached to the inner surface of the shell, and a groove is arranged on the outer edge of the inner cover for mounting a sealing rubber ring, so that the sealing rubber ring is tightly attached to the inner surface of the shell, and water is prevented from entering the shell from the gap between the outer edge of the inner cover and the inner surface of the shell.

The invention relates to the field of traditional Chinese medicine compositions, in particular to a traditional Chinese medicine composition for relaxing muscles, stimulating blood circulation and dredging collaterals and a preparation method and application thereof. Comprising the following raw materials in parts by weight: 10-18 parts of angelica sinensis, 22-30 parts of ligusticum wallichii, 10-18 parts of safflower carthamus, 10-18 parts of peach kernel, 10-18 parts of radix achyranthis bidentatae, 22-30 parts of earthworm, 10-18 parts of cassia twig and 22-30 parts of fructus psoraleae. Through the synergistic effect of the angelica sinensis, the ligusticum wallichii, the safflower, the peach kernel, the radix achyranthis bidentatae, the earthworm, the cassia twig and the fructus psoraleae, the traditional Chinese medicine has the effects of promoting blood circulation to remove blood stasis, relaxing tendons and dredging collaterals, dispelling wind and eliminating dampness, and relieving swelling and pain; modern pharmacological studies show that the prescription can improve local microcirculation, inhibit release of inflammatory factors, regulate immune response and promote repair of damaged tissues, so that the treatment targets of relieving pain and recovering functions are achieved.

The invention belongs to the field of biological medicine, and particularly relates to a traditional Chinese medicine composition for treating xerophthalmia and relieving asthenopia and a preparation method thereof, the traditional Chinese medicine composition comprises mulberry leaf, chrysanthemum, cassia seed, wolfberry, rehmannia, dogwood, moutan bark, Chinese yam, lily, poria cocos, rhizoma alismatis, dendrobe, Chinese angelica, marigold, blueberry, lycium ruthenicum, raspberry, lutein ester and bear gall gold powder. Through the scheme, the traditional Chinese medicine composition provided by the invention can effectively treat clinical symptoms of xerophthalmia, increase tear secretion, improve fundus microcirculation and increase ciliary muscle blood flow, thereby eliminating asthenopia symptoms and improving eyesight.

The invention discloses a traditional Chinese medicine tea drink for preventing and treating oral mucosa diseases and a preparation method of the traditional Chinese medicine tea drink. The traditional Chinese medicine tea drink is prepared from 10-15 parts of radix astragali, 8-12 parts of radix codonopsis, 6-10 parts of radix salviae miltiorrhizae, 5-9 parts of radix angelicae sinensis, 3-6 parts of fructus psoraleae, 6-9 parts of rhizoma polygonati, 6-9 parts of radix adenophorae, 6-10 parts of rhizoma atractylodis macrocephalae, 5-9 parts of radix ophiopogonis, 3-5 parts of radix glycyrrhizae, 4-6 parts of pericarpium citri reticulatae and 5-8 parts of herba taraxaci. Aiming at the core pathogenesis of low immunity, long-term deficiency, long-term deficiency and kidney-yang insufficiency of patients suffering from oral mucosa diseases, qi tonifying, blood activating and kidney-qi strengthening are taken as a core treatment method, the formula is scientific and reasonable, all the medicinal materials act synergistically, the overall immune function of the body is adjusted, T lymphocyte subpopulation imbalance and cell factor network disorder are improved, and the curative effect is good. The oral mucosa microcirculation is improved, local inflammation is relieved, the immunity of a patient is improved fundamentally, the recurrence rate of oral mucosa diseases is reduced, and the problems that an existing tea drink is not high in pertinence and limited in curative effect are solved. The tea drink is appropriate in taste, good in compliance, high in safety and suitable for people with various oral mucosa diseases and low immunity.

The invention discloses a prostate therapeutic instrument, and belongs to the technical field of medical instruments. A massage head slides at the front end of the shell, and a plurality of guide sliding grooves are evenly distributed in the massage head. A center column is fixed to the center of the shell, and a first disc body and a second disc body are arranged on the center column. A plurality of sliding sleeves are arranged between the first disc body and the second disc body in a circumferential array mode, connecting blocks are arranged on the multiple sliding sleeves, each connecting block is arranged in the corresponding guide sliding groove, and air cavities are formed in the multiple sliding sleeves; wherein a plurality of stand columns are arranged on the first disc body in the circumferential direction in an array mode, the stand columns are inserted into the corresponding air cavities in a sliding mode respectively, and each stand column is connected with an air pipe. Through an inflation and deflation circulation system driven by a micro air pump, the sliding sleeves can be regularly pushed to reciprocate along the stand columns, and then the massage heads are driven to generate displacement; pulse type mechanical stimulation on a prostate focus part is formed; the dynamic pressing can effectively promote microcirculation of prostate tissues.

The invention relates to a deep learning fundus blood flow imaging method based on OCT amplitude and phase information, and belongs to the field of fundus blood flow imaging. An artificial neural network is used for fusing multi-modal information from OCT, multiple labels from OCTA are used for optimizing the network, and finally high-precision reconstruction of a blood flow image is achieved. Compared with the prior art, the method has the following outstanding advantages that firstly, phase information which is not fully utilized in a traditional method is creatively integrated, and the microvessel recognition sensitivity is remarkably improved through an amplitude-phase bimodal feature collaborative learning mechanism; secondly, a blood flow texture-blood flow position double-label supervised learning strategy is creatively provided, blood vessel position labels are introduced in a function loss stage, the network is assisted to accurately position the blood flow position, the characterization capacity of the network on capillary and other small blood vessel structures is effectively enhanced, and blood flow microcirculation visualization is achieved; and thirdly, blood flow information can be reconstructed by using single OCT scanning data.

The present application relates to the technical field of medical diagnosis, and discloses a blood oxygen real-time monitoring system based on a photoelectric volume pulse wave, which comprises the following steps: inducing a vasomotor response through periodic thermal excitation, and demodulating a physiological pulse wave from a thermal modulation signal by using a synchronous phase-locked amplification technology. The present application solves the signal acquisition problem in a silent low perfusion state, converts background signals regarded as invalid noise in traditional monitoring into a resolvable vital sign carrier, and realizes non-invasive evaluation of microcirculation function through a thermal response index, thereby providing an early screening means for peripheral vascular diseases. The system maintains medical-grade precision while realizing the engineering feasibility of a consumer-grade device with an extremely simple hardware architecture.

This invention relates to the field of medical device technology, and more particularly to an intelligent probe patch for monitoring blood circulation in microscopic free flaps, comprising: a disposable probe patch configured to be attached to the surface or edge of the free flap; a biocompatible adhesive layer is provided on the bottom surface of the flexible base of the disposable probe patch, and an auxiliary structure is provided on the top of the flexible base to resist postoperative tissue activity or secretions; the disposable probe patch integrates an optical sensing unit and a temperature sensing unit for collecting local blood oxygen saturation, pulse rate, and surface temperature of the flap, respectively; a repeater, establishing non-contact near-field coupling with the disposable probe patch, the repeater being configured to provide working power to the disposable probe patch through near-field coupling, enabling it to operate without a built-in battery; and synchronously receiving physiological parameter data reflecting the local microcirculation status of the flap collected by the disposable probe patch; and a terminal device, wirelessly connected to the repeater, receiving and processing the physiological parameter data.

The application discloses a tongue fur and finger end microcirculation combined detection device based on multispectral fusion. The device synchronously applies multi-band optical excitation to the tongue detection area and the finger end detection area through an excitation unit, forming a multispectral excitation sequence; a collection unit obtains the reflection, absorption and scattering response of the tongue under different spectral excitation conditions, generating a tongue multi-layer spectral response data set; a response unit collects the deep optical interference and polarization change of the finger end, and extracts a finger end microcirculation dynamic parameter set; a modeling unit constructs a cross-tissue feature constraint relationship between the tongue tissue response and the finger end microcirculation response, and generates a joint feature constraint vector; a generation unit performs joint mapping calculation on the tongue multi-layer spectral response data set and the finger end microcirculation dynamic parameter set under the limitation of the joint feature constraint vector, and outputs a constitution type identifier and a constitution stability evaluation index, so that the collaborative constraint of multi-site physiological information and reliable constitution determination are realized.