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426results about How to "Little side effects" patented technology

Novel interventional medical device

The invention provides a novel interventional medical device, which comprises a ball, a catheter and a connecting device, wherein the catheter connects the ball and the connecting device and is a four-cavity tube, a thread guide cavity, an expansion cavity, an isolating cavity and a medicine transmission cavity are formed in the catheter, and the thread guide cavity runs through the whole catheter. A far-end ball, a middle ball and a near-end ball are arranged on the far end of the four-cavity tube; the far-end ball and the near-end ball can be communicated with the connecting device through the isolating cavity and the middle ball can be communicated with the connecting device through the expansion cavity, and thus, the far-end ball and the near-end ball can stop blood flow in an operation process so as to form a temporary closed cavity; and the middle ball can conduct an expansion function. In addition, the temporary closed cavity can be communicated with the connecting device through the medicine transmission cavity. When the novel interventional medical device is used, the singleness of the function of the conventional ball expansion catheter is overcome, the narrow part in a blood vessel can be expanded, a medicine can be transmitted to the expanded blood vessel immediately, and the damage of the medicine to the normal blood vessel is prevented.
Owner:SHANGHAI MICROPORT MEDICAL (GROUP) CO LTD

Chinese medicine oral preparation for hair growth and hair blackening

The invention relates to a Chinese medicine oral preparation for hair growth and hair blackening, which comprises radix rehmanniae, rehmannia glutinosa, angelica sinensis, red-rooted salvia root, radix ophiopogonis, poria with hostwood, radix polygoni multiflori preparata, cacumen biotae, semen sesami nigrum, dogwood, pericarpium granati, folium mori, poria cocos, eclipta, glossy privet fruit, fructus psoraleae, herba siegesbeckiae and Chinese magnoliavine fruit. The Chinese medicine oral preparation for hair growth and hair blackening is prepared according to pathogenesis of traditional Chinese medical science. The eclipta has a function of fast growing hair; the radix polygoni multiflori preparata and the fructus psoraleae have functions of hair blackening and hair growth; the angelica sinensis and the poria with hostwood have functions of promoting blood production and tonifying heart, promoting blood circulation and removing blood stasis, improving microcirculation and the like; the glossy privet fruit, the radix rehmanniae, the rehmannia glutinosa and the folium mori are used for nourishing hair follicle; and the cacumen biotae, the semen sesami nigrum, the dogwood and the Chinese magnoliavine fruit are used as supplements, so that the Chinese medicine oral preparation for hair growth and hair blackening really plays a role in hair blackening, hair growth and hair nourishing through a synergistic effect of all the compositions. The Chinese medicine oral preparation for hair growth and hair blackening, provided by the invention, has the functions of blackening hair, prompting hair growth, prompting blood production and tonifying heart, promoting blood circulation and regulating vital energy, nourishing brain and kidney, and relaxing tendons and replenishing qi and blood, is free of any chemical composition harmful to a human body, has less side effect, is effective in treatment and simple to take, and has low preparation cost.
Owner:祁银学

Gastrointestinal series agent

The invention discloses a gastrointestinal series agent containing a Chinese medicinal extract. The gastrointestinal series agent consists of the following components in parts by weight: 50-70 parts of barium sulfate and 20-30 parts of a Chinese medicinal extract, wherein the Chinese medicinal extract is prepared with a preparation method comprising the following steps of: mixing 20-30 parts of heterophylly falsestarwort root, 10-20 parts of fried large-head atractylodes rhizome, 10-20 parts of pseudo-ginseng root, 20-30 parts of tall gastrodia tuber, 10-20 parts of fortune's drynaria rhizome, 20-30 parts of honeysuckle flower, 5-15 parts of fragrant solomonseal rhizome, 20-30 parts of dried orange peel, 10-20 parts of white paeony root, 5-10 parts of liquoric root and 10-20 parts of honey; adding water for soaking; decocting for 30-40 minutes; filtering a filtrate; and concentrating the filtrate under reduced pressure, and performing freeze drying to obtain a Chinese medicinal extract. The gastrointestinal series agent containing the Chinese medicinal extract has the advantages of small side effect, capability of conditioning or treating stomach, liver and the like apart from a radiography function, better use effect, suitability for patients suffering from gastric hemorrhage and wider application range.
Owner:QIANFOSHAN HOSPITAL OF SHANDONG

Sacculus expansion catheter for drug treatment

The invention provides a sacculus expansion catheter for drug treatment, which comprises a catheter and a plurality of sacculus bodies fixed on the catheter. The catheter adopts a multi-cavity catheter and comprises a guide wire cavity penetrating through the whole catheter, a sacculus expansion cavity and a drug loading cavity used for accommodating drugs; the sacculus expansion catheter is provided with at least two sacculus bodies which can be separated in expansion to form a closed blood vessel cavity between a blood vessel wall, the sacculus expansion cavity is respectively communicated with one or more corresponding sacculus body/bodies, and the expansion and contraction of the sacculus bodies are controlled through the sacculus expansion cavity; and the parts of the catheter between adjacent sacculus bodies are provided with an opening communicated with the drug loading cavity so that the drugs can be dissolved in the closed blood vessel cavity. Drug losses of the traditional sacculus expansion catheter for drug treatment can be overcome, the drugs can be dissolved in the blood of a patient to treat the pathological area, the narrow area of the blood vessel can be expanded effectively, the high-pressure effects of external drugs on the pathological blood vessel wall can be reduced, and potential adverse effects of the external drugs on the human body can also be avoided.
Owner:SHANGHAI VASOLUTIONS MEDTECH CO LTD

Chinese soft-shell turtle aeromonas phage and application thereof

The invention provides a Chinese soft-shell turtle aeromonas phage of which the preservation number is CGMCC: No. 9623. Partial sequence fragments of the nucleic acid of the phage and the aeromonas phage are above 75% in homology, bacteriophage plaque can be formed for the Chinese soft-shell turtle aeromonas hydrophila, and a splitting action can be played on pathogenic aeromonas, so the Chinese soft-shell turtle aeromonas phage can be used for treating and preventing diseases caused by the aeromonas by adopting a biological treatment method. The Chinese soft-shell turtle aeromonas phage disclosed by the invention has the beneficial effects of being high in specificity, small in side effects, high in multiplication capacity, hard to cause resistance and pathogenic bacteria dependence, convenient to use and capable of having a remarkable treatment effect on Chinese soft-shell turtle neck sore, white-spot diseases and the like. By adopting the Chinese soft-shell turtle aeromonas phage disclosed by the invention to treat the Chinese soft-shell turtle neck sore, the white-spot diseases and the like, the aims of realizing high specificity, small side effects, high multiplication capacity, hard generation of resistance and pathogenic bacteria dependence and convenience in use can be fulfilled.
Owner:ZHEJIANG INST OF FRESH WATER FISHERIES

Anti-influenza virus medicament screening model and application thereof

The invention relates to an anti-influenza virus medicament screening model, an anti-influenza virus medicament screening method and application, in particular to an influenza virus RNA polymerase suppressant screening model and the application thereof. The method of the invention comprises the following steps that: by utilizing the transcriptional activity of four polymerase (PB1, PB2, PA and NP) genes of influenza A viruses, cells are transfected with the four RNA polymerase genes and reporter genes, and the reporter genes are transcribed and expressed in the cells; and then anti-influenza virus medicaments are screened by detecting the luminous intensity of the fluorescence reporter genes generated by the transcription or indirectly detecting the variations of reporter gene substrates with a fluorescence detection apparatus, such as a fluorescence microscope and the like. In the invention, the novel anti-influenza virus medicament screening model adopts the RNA polymerase of which an influenza virus infection and growth cycle plays an important role and is relatively more stable so as to be expected to develop novel anti-influenza virus medicaments, which are used for damaging enzymatic structures or suppressing enzymatic activity and has high efficiency, low toxicity and little side effect.
Owner:CHINA PHARM UNIV

Taxus polysaccharide immunologic adjuvant and influenza vaccine containing same

The invention provides a taxus polysaccharide immunologic adjuvant and an influenza vaccine containing the same. The taxus polysaccharide immunologic adjuvant consists of the following components in percentage by mass: 0.001 to 100 percent of taxus polysaccharide and 0 to 99.999 percent of carrier. A mass ratio of the taxus polysaccharide immunologic adjuvant to hemagglutinin of the influenza vaccine is 50 to 183,500. The taxus polysaccharide is a natural substance extracted from branches of taxus; when the taxus polysaccharide is used as the immunologic adjuvant, applicable experiment results are obtained, and the taxus polysaccharide has high safety and small side effect. The influenza vaccine containing the taxus polysaccharide immunologic adjuvant is easy and convenient to prepare, the quality of the vaccine is easy to control, the immunogenicity of the vaccine can be better improved, and the dosage of antigen of the vaccine is greatly reduced; experiments prove that the dosage ofthe antigen of the vaccine, which takes the taxus polysaccharide as the adjuvant, is only half or lower than half of the dosage of the antigen of the vaccine, which takes aluminum hydroxide as the adjuvant, but the immune protective effect is the same.
Owner:INST OF MEDICAL BIOLOGY CHINESE ACAD OF MEDICAL SCI

Preparation method of healthcare dragon beard tea

InactiveCN103734423ALittle side effectsImprove kidney functionTea substituesHigh Blood PressuresPlastic bag
The invention relates to a preparation method of healthcare dragon beard tea. The method comprises the following steps: (1) removing upper blackheads and impurities from corn stigmas taken as a raw material, picking out impurities from radix polygonati officinalis taken as another raw material, respectively smashing the corn stigmas and the radix polygonati officinalis, and then sieving the smashed corn stigmas and the smashed radix polygonati officinalis through a sieve of 50 meshes; (2) weighing the treated corn stigmas and the treated radix polygonati officinalis according to the mass ratio of 2:1, adding certain amount of pure drinking water into the weighed materials and evenly mixing; (3) granulating the matched materials in a granulator with a sieve of 50 meshes; (4) evenly spreading the granulated dry materials in a stainless steel disc and performing drying sterilization; (5) sieving the whole granules from the dried material granules by a sieve of 2mm, selecting the partial intermediate granules, removing fine powder and sieving off coarse granules; and (6) sub-packaging the obtained granules by a tea sub-packaging machine and filter cotton paper under the condition that each bag contains 2.0g of granules, putting the sub-packaged paper bags into a plastic bag and cartoning the plastic bag, thereby obtaining the finished product, namely, the dragon beard tea. The dragon beard tea can be used for preventing the occurrence of high blood pressure, high blood fat and high blood sugar and cannot generate toxic and side effects, and does no harm to a human body.
Owner:公主岭国家农业科技园区九正生物医药科技有限公司
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