1356 results about "Combined treatment" patented technology

A method is provided for treatment of cataract in combination with a glaucoma procedure while maintaining the intraocular pressure by permitting aqueous to flow out of an anterior chamber of the eye through a surgically stented pathway. A trabecular stent is adapted for implantation within the trabecular meshwork of an eye such that intraocular liquid flows controllably from the anterior chamber of the eye to Schlemm's canal, bypassing the trabecular meshwork. Depending upon the specific treatment contemplated, pharmaceuticals may be utilized in conjunction with the trabecular stent enabling post-cataract healing processes.

The present invention provides a comprehensive solution to skin problems of infants and incontinent adults related to diaper rash, also known as diaper dermatitis. This is based on certain novel divalent metal and quaternary ammonium complexes (ion-pairs) of zeolites (that are made by an in-situ process), which in synergistic combination with certain other compositions, provide a comprehensive treatment for diaper rash that encompasses the following aspects: (1) deactivation of lipase and protease enzymes on skin surface, (2) the controlled-release delivery of skin protectant compositions, such as divalent metal zinc cation, (3) trapping of acidic and alkaline chemicals deposited on skin from body exudates and enzyme activity, (4) controlled-release delivery of anti-inflammatory agents, and COX and LOX enzyme inhibitors, (5) controlled-release delivery of antibacterial and antifungal compositions, and (6) absorption of excess moisture in the diaper zone.

A method is provided for treatment of cataract in combination with a glaucoma procedure while maintaining the intraocular pressure by permitting aqueous to flow out of an anterior chamber of the eye through a surgically stented pathway. A trabecular stent is adapted for implantation within the trabecular meshwork of an eye such that intraocular liquid flows controllably from the anterior chamber of the eye to Schlemm's canal, bypassing the trabecular meshwork. Depending upon the specific treatment contemplated, pharmaceuticals may be utilized in conjunction with the trabecular stent enabling post-cataract healing processes.

A cryoprobe supports administration of an active agent to a location of cryogenic treatment. The cryoprobe may optionally be combined with a syringe to form a cryoprobe system; alternatively and optionally, the syringe may be external to the cryoprobe.

A medical treatment planning system includes a computer including a processor and memory, data stored in the memory, said data including a priori of information relating to medical conditions, medical treatments and treatment results, and treatment planning logic stored in the memory and executable by the processor. The treatment planning logic includes logic that obtains pre-treatment patient data describing the patient's medical condition, logic that analyzes the pre-treatment patient data relative to the a priori of information and, based on the analysis, formulates a first treatment plan for treating the patient, and logic that outputs the first treatment plan for evaluation by medical personnel.

Chemotherapeutic treatment for certain cancers may be combined with low intensity, intermediate frequency alternating electric fields that are tuned to a particular type of target cell. When the tuned fields were combined with Paclitaxel, Doxorubicin or Cyclophosphamide, excellent results were obtained against human breast cancer cells (MDA-MB-231) and non-small cell lung (H1299) carcinomas in culture. More specifically, cell proliferation inhibition similar to that obtained by drug alone was reached by exposure to the combined treatment at drug concentrations between one and two orders of magnitude lower than for drug-only regimens of treatment.

The present invention provides a method for treating tumors or tumor metastases in a patient, comprising administering to the patient simultaneously or sequentially a therapeutically effective amount of an EGFR kinase inhibitor and gemcitabine combination, with or without additional agents or treatments, such as other anti-cancer drugs or radiation therapy. The invention also encompasses a pharmaceutical composition that is comprised of an EGFR kinase inhibitor and gemcitabine combination in combination with a pharmaceutically acceptable carrier. A preferred example of an EGFR kinase inhibitor that can be used in practicing this invention is the compound erlotinib HCl (also known as Tarceva™).

The invention provides a method, and dosage form therefor, of treating impaired motor function associated with Parkinson's disease, anti-Parkinson's drug treatment, e.g. L-Dopa therapy, and / or dementia associated with Parkinson's disease. The invention includes the combined administration of an NMDA receptor antagonist and an antidepressant, e.g., the combination of amantadine and citalopram or venlafaxine, or an NMDA receptor antagonist and an anxiolytic agent, e.g., amantadine and buspirone or trazodone, for the amelioration of undesired tremors, akinesia, dyskinesia, or bradykinesia associated with one or more different disorders or diseases. The drugs can be included in a single dosage form. One embodiment includes a combination dosage form containing each drug in controlled release forms. Another embodiment includes a combination dosage form providing a controlled release of an NMDA receptor antagonist and a rapid release of a neuroactive agent after administration to a subject.

The invention discloses integrated equipment for omnibearing treatment of kitchen garbage and a production method of products. The equipment comprises a central intelligent automatic control system, an air treatment system, a straw biochemical system, an advanced oxidization artificial forced inactivation system, a combined screening and impurity removal system, a compound biochemical system, an automatic drying system, a combined conveying system, a waste plastic reversion engineering system, a sludge treatment system, a sewage treatment system, an oil treatment system and a hot smoke combined treatment system. Produced finished products comprise high-nutrition microbial protein feed, mineral state III diesel, biodiesel, emulsification diesel, low-sulfur clean fire coal, hybrid charge adsorbents and industrial recycle water. A recycling rate of the kitchen garbage reaches above 95%; basically no waste water is discharged, no sludge is transferred, no room temperature discharge exists, no peculiar smell or smoke is discharged and no residue is transferred during production; and the environment-friendly, safe and reliable highly-integrated production equipment and the production method are provided for the treatment of the kitchen garbage.

The present invention provides a method for treating NSCL, pancreatic, colon or breast cancer tumors or tumor metastases in a patient, comprising administering to the patient simultaneously or sequentially a therapeutically effective amount of a combination of an EGFR kinase inhibitor and an agent that sensitizes tumor cells to the effects of EGFR kinase inhibitors, wherein the agent is an mTOR inhibitor, with or without additional agents or treatments, such as other anti-cancer drugs or radiation therapy. The present invention also provides a method for treating tumors or tumor metastases in a patient, comprising administering to said patient simultaneously or sequentially a therapeutically effective amount of a combination of an EGFR kinase inhibitor and an agent that sensitizes tumor cells to the effects of EGFR kinase inhibitors, wherein said agent is an mTOR inhibitor that binds to and directly inhibits both mTORC1 and mTORC2 kinases. The present invention also provides a pharmaceutical composition comprising an EGFR kinase inhibitor and an mTOR inhibitor that binds to and directly inhibits both mTORC1 and mTORC2 kinases, in a pharmaceutically acceptable carrier. A preferred example of an EGFR kinase inhibitor that can be used in practicing the methods of this invention is the compound erlotinib HCl (also known as TARCEVA®).

Chemotherapeutic treatment for certain cancers may be combined with low intensity, intermediate frequency alternating electric fields that are tuned to a particular type of target cell. When the tuned fields were combined with Paclitaxel, Doxorubicin or Cyclophosphamide, excellent results were obtained against human breast cancer cells (MDA-MB-231) and non-small cell lung (H1299) carcinomas in culture. More specifically, cell proliferation inhibition similar to that obtained by drug alone was reached by exposure to the combined treatment at drug concentrations between one and two orders of magnitude lower than for drug-only regimens of treatment.

The present invention relates to a Chinese medicine composition for curing asthma radically. Said medicine is made of 40 Chinese medicinal materials of Sichuan fritillaria bulb, Zhejiang fritillaria bulb, tussilago flower, stemona root, aster root, licorice and others as raw material according to a certain mixing ratio through a certain preparation process.

The invention provides a new combined treatment process for oilfield solid waste (oil sludge, industrial solid waste and household garbage). In the process, liquid-solid separation is performed on the oil sludge of an oilfield by adopting a conditioning-centrifugal separation process; the separated liquid enters oil-water separation equipment constructed on the oilfield for recovering crude oil; the oil recovery rate is up to 65 to 90 percent; after drying separated solid residue, the separated solid residue and pre-crushed industrial solid waste and household garbage are mixed and enter a countercurrent-type rotary gasification incinerator; combustible components in the oilfield solid waste are decomposed and gasified into combustible gases which are combusted partially in the incinerator; the combustible gases are combusted completely in a secondary combustion chamber; high-temperature smoke gas afterheat is recovered by a conduction oil afterheat boiler and air preheating equipment; and low-temperature smoke gas of which the afterheat is recovered is harmlessly exhausted after being treated by a sharp-quenching deacidification tower, an activated carbon adsorption tower and a bag-type dust remover. The process realizes the purposes of decrement, harmlessness and resources of oilfield solid waste treatment.

The present invention provides a method for treating NSCL, pancreatic, colon or breast cancer tumors or tumor metastases in a patient, comprising administering to the patient simultaneously or sequentially a therapeutically effective amount of a combination of an EGFR kinase inhibitor and an agent that sensitizes tumor cells to the effects of EGFR kinase inhibitors, wherein the agent is an mTOR inhibitor, with or without additional agents or treatments, such as other anti-cancer drugs or radiation therapy. The present invention also provides a method for treating tumors or tumor metastases in a patient, comprising administering to said patient simultaneously or sequentially a therapeutically effective amount of a combination of an EGFR kinase inhibitor and an agent that sensitizes tumor cells to the effects of EGFR kinase inhibitors, wherein said agent is an mTOR inhibitor that binds to and directly inhibits both mTORC1 and mTORC2 kinases. The present invention also provides a pharmaceutical composition comprising an EGFR kinase inhibitor and an mTOR inhibitor that binds to and directly inhibits both mTORC1 and mTORC2 kinases, in a pharmaceutically acceptable carrier. A preferred example of an EGFR kinase inhibitor that can be used in practicing the methods of this invention is the compound erlotinib HCl (also known as TARCEVA®).

Disclosed are methods, compositions of matter and cells for treatment of cardiovascular disease through concurrent inhibition of oxidative stress while administration of a cell therapy. The invention also concerts the modulation of oxidative stress for preferential induction of differentiation while concurrently inhibiting inflammatory processes that decrease efficacy of cellular therapy.

The invention relates to an urban sludge, excrement and kitchen garbage combined treatment process as a novel process, in particular to an urban sludge, excrement and kitchen garbage combined treatment process under the demands of lower investment from government, less occupying area and lower running cost. In the combined treatment process, a pretreatment unit, a combined tempering unit, an intermediate-temperature anaerobic digestion unit, a digestive juice dewatering unit, a methane purifying unit and a biogas treating unit are included. The invention provides a novel treatment process in order to solve the problems of pollution from urban sludge, excrement and kitchen garbage.

The combined treatment process of high concentration ammonia nitrogen waste water belongs to the field of waste water treating technology. The combined treatment process of high concentration ammonia nitrogen waste water features the combination of blow-off method, MAP method and nitrosation-anaerobic ammoxidation biological method. The treating process of the present invention includes the steps of: adding lime into the waste water in a regulating tank to reach pH of 11-12; blow-off and aerating in a blow-off tank, with the blow-off tail gas entering to an absorbing tank and the blow-off water entering to a MAP reaction tank; treating the blow-off effluent in the MAP reaction tank with thrown disodium hydrogen phosphate and magnesia to produce magnesium ammonium phosphate precipitate exhausted; and the final nitrosation-anaerobic ammoxidation biological treatment. The process has low power consumption and other advantages.

Age-related macular degeneration (AMD) results in the formation of new blood vessels in the eye. The walls of these vessels leak fluid, which causes scarring in the surrounding tissue and results in reduced vision or loss of vision. Photodynamic therapy (PDT) alone has been used to treat AMD, but many retreatments are needed, which cause further damage to the already diseased area. Laser treatment to coagulate the fluid actually causes additional new vessels to form. However, the inventive method of treating patients with both PDT and scatter threshold laser coagulation therapy surprisingly either improved vision, or prevented further loss of vision. Moreover, the combined treatment eliminated the need for retreatment, and did not generate new vessel growth. Threshold laser coagulation and PDT may be administered within the same treatment session or either may be administered first and the other may be administered within ninety days.

The invention relates to a biological contact oxidation and artificial wetland bioecological combined treatment system for the grey water of a residential area. The system consists of a biological contact oxidation pre-treatment device and an artificial wetland post-treatment device. The system treats the grey water of the residential area and recycles the treated water as the water for landscapes of environment-friendly buildings by using biological contact oxidation and artificial wetland combined technology as the technical core; and the water quality of the outlet water reaches the restrictive control index TN of the standard for landscape recycled water. For the grey water of the residential areas of different concentrations, the system can meet the requirements of the landscape recycling standard on the outlet water by adjusting the operating mode of the combined technology: an intermittent operating mode is used for the grey water of the residential areas of high pollution concentration; a continuous aeration operating mode of low gas-water ratio is used for the grey water of the residential areas of low pollution concentration; the treated grey water can be used as the water for the landscapes of the environment-friendly buildings; and the system has a simple structure and low operating cost and is a practical and feasible technical system for the treatment of the grey water of the residential areas suitable for the conditions of China.

It is a method for preparation and the special device of nanocrystalline ingotting from metallic fondant treated jointly by magnetic field and supersonic wave, solving the present technique problem of complex device, high cost, and difficulty to prepare large-scale nanometer material and so on. The invented method is as the following steps: melting and heating the matched raw material, deairing the metallic fuse-elements, pouring rapidly the deaired metallic fuse-elements into preheated crucible, heating upwards the liquidus curve, applying electromagnetic mixing and ultrasonic vibration, chilling until it freezes totally, then the block-shaped nanocrystalline ingotting being prepared; the special device that applied joint treatment of electromagnetic mixing and ultrasonic vibration having a holding furnace, which is equipped with a crucible, the special being characterized in that outboard of the holding furnace is equipped with magnetic field generator, over the crucible there is a ultrasonic transducer, and bottom of the crucible is equipped with a chiller.

The invention relates to a natural active drug-polysaccharide targeted compound with antitumor activity and targeting property. A natural active drug is introduced onto a polysaccharide framework by chemical grafting, and physically mixed with a ligand distearoylphosphatidyl ethanolamine-polyethyleneglycol-anisoyl amine with targeted transmission capacity to form a natural active drug-polysaccharide targeted compound, and the natural active drug-polysaccharide targeted compound can be self-assembled in water to form a nano micelle. The method is characterized in that the natural active drug-polysaccharide targeted compound has targeted transmission capacity, enhances the tumor transfer efficiency of the preparation, reduces the untoward reaction and enhances the tolerance of the patient; the hydrophobic inner core formed by the hydrophobic group can physically wrap the antineoplastic drug, thereby obviously improving the water solubility of the antineoplastic drug; and the antineoplastic drug which is physically wrapped by the chemically coupled ursolic acid can implement combined treatment of tumors and lower the toxic or side effect. The preparation method is simple and easy to operate, has the advantage of higher yield, and can easily implement industrialization.

Methods for controlling contamination of a food product are provided which utilize a combined treatment comprising thermal surface treatment and introduction of an antimicrobial solution to a food package prior to vacuum sealing the package.

A comprehensive localized therapy method and equipment for tumor features that various endoscopes are used to inject the magnetic immune microspheres carrying biologic medicine and the antineoplastic magnetic chemical medicine into tumor focus, the liquid radioactive source is poured in the inner cavity of catheter, and an alternative magnetic field is generated around the tumor focus to induce the microspheres to generate heat and adsorbing the antineoplastic medicine to round the tumor focus. Its advantage is the combination of biotherapy, chemicotherapy, radiotherapy and thermotherapy.

Systems and methods of the present invention provide a calibration model that requires minimal information compared with prior techniques. These systems and methods represent the first generalized approach for combined treatment of spectroscopic measurements of a dynamic, mass-transfer system with the underlying kinetic model of said system. The technique can be applied to non-invasive glucose monitoring or monitoring of chemical reaction dynamics.

The invention discloses an industrial production method of hydrolyzed wheat protein for feeding, belonging to the technical field of feed additive production. In the method, through the method of synergy of multiple enzymes and combined treatment of multiple steps, the hydrolyzed wheat protein for feeding is prepared by taking wheat gluten meal and water with weight ratio of 1:10-1:2 and adding compound enzyme, ensuring the mass percent concentration of the compound enzyme in the solution is 0.2-1.4%, hydrolyzing the mixture for 1-13h under the conditions that the temperature is 30-70 DEG C and pH value is 5.0-10.0, then carrying out such processes as filtering, decoloring and drying, etc. Compared with the traditional methods, the method of the invention features mild hydrolysis conditions, sanitation and safety and maintains the original nutritive composition of amino acid free of loss; the hydrolysate is low in salt content, mellow in mouth feel and high in yield which is up to 98%. The tests that the hydrolyzed wheat protein is added in the feed for suckling pigs, chicks, calves, aquaculture and the like to be used show that the hydrolyzed wheat protein has the advantages and evident effects of improving daily feed intake, reducing diarrhea rate, enhancing immunity, slowing weanling stress, improving growth performance and the like.

A bariatric treatment system providing a comprehensive array of therapeutic services for the morbidly obese patient is disclosed. The treatment system generally comprises a stable bed frame upon which is mounted a low air loss therapeutic mattress system. Integrated hardware and software controls provide such therapies as pulsation, percussion, rotation, cardiac chair and Trendelenburg. Means are disclosed whereby the bariatric patient may safely and comfortably enter and exit the bed with relative ease. The bed is adaptable for transport within a hospital, including such features as a TRANSPORT MODE wherein the bed's lateral axis is minimized and battery backup to maintain necessary therapies during patient transport. A plurality of control means are disclosed for simplification of caregiver workload and ease of patient utilization.

The invention relates to a combined treatment technology for oil-containing sludge, which is particularly suitable for oil-containing sludge which is generated in sewage treatment processes of petrochemical plants. The method comprises: adding a texturizer into the oil-containing sludge for texturizing treatment, adding an oil displacement agent for uniformly mixing, mechanically dehydrating the oil-containing sludge to reduce a water content to 50-90%, then sending the oil-containing sludge into squeezing equipment for squeezing, mixing mud cakes after squeezing with a mixed extractant, uniformly stirring for extraction, sending a mixture into a solid-liquid separator after extraction, introducing a separated liquid into a rectifying tower for regenerating the extractant, and mixing separated solid residue after dried with coal to used as a fuel. The treatment technology of the invention has advantages of low energy consumption for oil-containing sludge treatment, and fast extraction speed, can recover oil in the oil-containing sludge, and can implement resource utilization and harmlessness treatment of the oil-containing sludge.

The invention relates to a method for performing combined treatment on livestock and poultry excrement, straws and sewage. The method mainly comprises two processes of anaerobic fermentation and biological contact oxidation and comprises the main steps of: 1) mixing the crushed straws, excrement and sewage and performing anaerobic fermentation treatment; 2) removing suspended matters from methane liquid generated by the anaerobic fermentation treatment, homogenizing water quality, removing oil, performing biological contact oxidation treatment to reduce chemical oxygen demand (COD) and ammonia nitrogen, precipitating and draining water for agricultural irrigation; and 3) dehydrating and desulfurizing methane generated by the anaerobic fermentation treatment to serve as energy and composting methane slag to prepare into organic fertilizer. The invention also discloses a device for implementing the method. The device can treat the livestock and poultry excrement, the straws and the sewage, can also generate methane, realizes resource utilization of wastes and has the characteristics of simple and intensive process, higher utilization ratio of the resources and good operation effect.

The invention discloses a nanometer medicine particle. The nanometer medicine particle comprises a hydrophobic polymer, a single-layer lipid molecule, an amphipathy macromolecular compound, at least one chemotherapy drug attached to the hydrophobic polymer, and at least one near-infrared photothermal conversion agent, wherein the hydrophobic polymer, the at least one chemotherapy drug attached to the hydrophobic polymer, and the at least one near-infrared photothermal conversion agent form a hydrophobic core; the single-layer lipid molecule surrounds the surface of the hydrophobic core to form an intermediate layer; and the amphipathy macromolecular compound intersperses in the intermediate layer to form a shell. The invention also provides a preparation method of the nanometer medicine particle. The nanometer medicine particle can realize the combined treatment of thermotherapy and chemotherapy and has high biocompatibility; and the preparation method is simple, convenient and easy to carry out.