The invention relates to a detection method for supermolecular
chirality of an amplified interface monomolecular film, belongs to the field of supermolecular
chirality, and solves the problems of inaccurate
chirality detection and difficult quantitative characterization of supermolecular chirality when an in-situ second-order
nonlinear optical method is used for detecting an interface monomolecular film with small chirality in the prior art. The invention discloses a method for detecting supermolecular chirality of an amplified interface monomolecular film. The method comprises the following steps: S1, dissolving chiral molecules in a volatile
solvent to obtain a sample solution; s2, respectively spreading the sample solution on the surface of pure water and the surface of the protonated achiral molecule solution, and after the
solvent is completely volatilized, self-assembling chiral molecules on an interface to form a monomolecular film; s3, detecting an SHG
signal of the monomolecular film in situ, and quantitatively characterizing the supramolecular chirality of the monomolecular film; and S4, detecting an SFG
signal of the monomolecular film in situ, and judging the group chirality and molecular
assembly mechanism of the monomolecular film. The method for amplifying and quantitatively characterizing the
supermolecule chirality of the monomolecular film is simple and easy to operate.