12results about How to "Scalable production" patented technology

This invention discloses a method for preparing fermented Chinese medicine wine, comprising the following steps: S1: Preparing brewing grains by weight, soaking, steaming, and treating with saccharifying enzymes to obtain saccharified grains; S2: Treating Chinese medicinal materials with compound enzymes to obtain enzymatically hydrolyzed Chinese medicinal materials; S3: Mixing the saccharified grains and enzymatically hydrolyzed Chinese medicinal materials, adding yeast for anaerobic fermentation to obtain fermented material; S4: Distilling and aging the fermented material to obtain fermented Chinese medicine wine. The advantages of this invention compared to existing technologies are: providing a method for preparing fermented Chinese medicine wine that achieves efficient release and full conversion of the effective components of Chinese medicinal materials, ensuring a mellow flavor and stable quality.

The invention discloses a synthesis method and application of high-relaxation-rate manganese-based nanogel. The synthesis method comprises the following steps: S1, dissolving VCL, AA, VPA, BAC and SDS in water; s2, under the protection of nitrogen, stirring the solution at 70 DEG C to realize homogenization, and initiating a further polymerization reaction by using AAPH to generate nanogel; s3, after the polymerization reaction is finished, purifying the nanogel by adopting an HCL precipitation and NaOH redissolution method so as to remove unreacted monomers; s4, after purification is finished, an HEPES buffer solution with the pH being 7.4 is used for dissolution, a MnCl2 solution is added for a reaction at the temperature of 37 DEG C, and the manganese-based nanogel is obtained. The r1 relaxation rate of the manganese-based nanogel reaches up to 29.8 mM <-1 > S <-1 > under the field intensity of 3.0 T, and the manganese-based nanogel is uniform in size, controllable in particle size, high in long-term stability, free of cytotoxicity, good in biological safety and capable of being applied to magnetic resonance imaging T1WI enhancement of liver, kidney and bone tumors.

The invention provides power generation cloth based on friction power generation and a preparation method thereof.The power generation cloth comprises a first friction assembly and a second friction assembly, and friction-based power generation is achieved through friction between the first friction assembly and the second friction assembly, the first friction assembly comprises a strip-shaped fabric composite layer, a conductive fabric layer and a ring-shaped fabric composite layer, the strip-shaped fabric composite layer and the conductive fabric layer are stacked in parallel, and the ring-shaped fabric composite layer surrounds the strip-shaped fabric composite layer and the conductive fabric layer which are stacked in parallel. The invention belongs to a green, clean and renewable energy source conversion technology. The power generation cloth disclosed by the invention has high elasticity, high flexibility, high flame retardance and washability. According to the power generation cloth, various mechanical energy can be converted into electric energy, the conversion efficiency is improved, and resource waste is reduced to a certain extent.

The invention belongs to the technical field of lipopeptide preparation, genetic engineering and biological medicine, and particularly relates to novel double-fat-chain lipopeptide as well as a preparation method and application thereof. According to the invention, a novel artificial gene cluster rhc is successfully constructed through precise editing and recombination of a functional module of a natural non-ribosomal lipopeptide gene cluster, and after heterologous expression of the gene cluster, a brand new double-fat-chain lipopeptide product Rhcolide A can be synthesized; the rhc gene cluster used for preparing the novel double-fat-chain lipopeptide Rhcolide A is the first artificial double-fat-chain lipopeptide synthetic gene cluster constructed through genetic engineering modification. A biological function test verifies and finds that Rhcolide A has excellent ferroptosis sensitizing activity, can be used as a ferroptosis sensitizer to be combined with a ferroptosis inducer to prepare a non-small cell carcinoma resisting drug, provides a brand new drug molecular entity for treatment of non-small cell carcinoma, and has important clinical application value and industrialization prospect.

This invention discloses a sustained-release cocrystal of insect behavior regulators, its preparation method, and its applications. The cocrystal of this invention is formed from raw materials including insect behavior regulators and ligands; the ligands are selected from at least one of agrochemicals. The novel cocrystal of insect behavior regulators and ligands provided by this invention exhibits excellent sustained-release performance, a constant release rate, a long sustained-release period, and stable effects, surpassing existing pure insect behavior regulators and commercially available rubber stopper carriers, and has promising application prospects.

The application belongs to the technical field of vegetable planting, and discloses an ecological planting method for big green onions, which takes a polyglutamic acid-silicate mineral grid fertilizer as a core, combines a green auxiliary prevention and control reagent and scientific field management, and specifically comprises the steps of soil pretreatment, seedling transplanting, precise fertilization in stages, green disease prevention and control, and whole-process ecological field management. The application realizes the synergistic unity of soil improvement, green disease prevention and control and yield improvement for the big green onions in a heavy-rotation plot, significantly improves the physicochemical indexes such as soil pH and bulk density, greatly reduces the number of fusarium, controls the total disease incidence of the big green onions within 7.3%, increases the yield per mu to more than 4390 kg, and is green, environmentally friendly, sustainable, simple, scalable, and suitable for the ecological planting of the big green onions in the heavy-rotation plot for more than 3 years.

The application relates to the technical field of liquid flow batteries, and discloses a high-stability flow channel plate, a preparation method thereof and a liquid flow battery, which comprises the following steps: processing and shaping a conductive plate material, and performing plasma pretreatment to introduce active groups on the surface of the conductive plate material, so as to obtain a pre-oxidized flow channel plate; preparing film-forming slurry, wherein the film-forming slurry comprises a solvent, a dispersing agent, a perfluoroalkyl phosphonic acid and a conductive agent; soaking the pre-oxidized flow channel plate in the film-forming slurry, and performing a self-assembly reaction under light-proof conditions, so that the perfluoroalkyl phosphonic acid is chemically bonded with the active groups on the surface of the pre-oxidized flow channel plate through phosphonic acid groups, and the conductive agent is distributed in a hydrophobic film layer formed by the perfluoroalkyl phosphonic acid, so as to construct a hydrophobic conductive composite film; and cleaning and drying the flow channel plate after the reaction, so as to obtain the high-stability flow channel plate. The application has the advantages of high conductivity, hydrolysis resistance, acid and alkali resistance, high-temperature resistance, blistering resistance and low cost.

The invention provides a nitrocellulose membrane with a backing as well as a preparation method and application of the nitrocellulose membrane, and belongs to the technical field of high polymer materials. The preparation method of the nitrocellulose membrane with the backing comprises the following steps: S10, dissolving nitrocellulose, a pore-foaming agent and a hydrophilic polymer in DMF (Dimethyl Formamide) and / or DMA (Dimethyl Formamide), and filtering and degassing to obtain a uniform and stable nitrocellulose membrane casting solution; s20, the nitrocellulose membrane casting solution is subjected to membrane scraping forming on a backing made of a PVC material, and a precursor membrane is obtained; s30, performing phase splitting on the precursor film in a solution to obtain a semi-wet film; and S40, washing and drying the semi-wet membrane to obtain the nitrocellulose membrane with the backing. The nitrocellulose membrane with the backing has the characteristics of uniform and controllable aperture, good hydrophilicity, strong protein binding capacity, large-scale production and the like, and has a wide application prospect in the field of in-vitro diagnostic reagents.

The invention belongs to the technical field of electromagnetic wave regulation and control, and particularly discloses a transmission and reflection integrated beam regulation and control unit and a metasurface array system.The beam regulation and control unit is of a seven-layer structure including four metal layers and three medium / bonding layers from top to bottom, transmission and reflection mode switching is achieved through PIN diode on-off control, and the metasurface array system is formed. 180-degree phase difference can be generated in the two modes, interlayer signal transmission is achieved through plated-through holes, the electromagnetic performance is improved through inductors, and direct-current and alternating-current signals are isolated. The array system is composed of M * N units and is matched with a feed source antenna and a control module, transmission beam scanning, reflection, retroreflection and transmission and reflection cooperative work are achieved through three control methods, and directional communication and radar echo camouflage / enhancement are completed at the same aperture. The device is compact in structure, low in cost, low in power consumption, stable in phase regulation and control, adaptive to light platforms such as an unmanned aerial vehicle and capable of being applied to scenes such as cooperative communication and electronic countermeasure.

The invention discloses a Cu-Lis self-assembled nano-drug as well as a preparation method and application thereof, and belongs to the technical field of nano-medicines. The nano-drug is formed by self-assembly of Cu < 2 + > and liensinine (Liensinine, Lis) under mediation of polyvinylpyrrolidone (PVP) at room temperature, the particle size is 11.14 nm, the surface potential is-8.04 mV, and the nano-drug has good physiological stability and biological safety. According to the invention, an LCD-pyroptosis cycle injury amplification effect is utilized to cooperate with a tumor killing and immune reprogramming mechanism of copper death for the first time, osteosarcoma cells are induced to generate strong pyroptosis and immunogenic cell death, and an immunosuppression microenvironment is reconstructed. The preparation method of the Cu-Lis self-assembled nano-drug is mild in condition, raw materials are easy to obtain, large-scale production can be achieved, and the Cu-Lis self-assembled nano-drug has remarkable application prospects in the field of osteosarcoma immunotherapy.

The invention discloses an efficient preparation method of a hard carbon composite material, which solves the problems of high energy consumption and low efficiency of high-temperature treatment and need of inert gas protection in the existing hard carbon preparation method, high specific capacity and high initial coulombic efficiency are obtained, the prepared product is good in conductivity and high in activity, and the obtained material mainly has the following characteristics: (1) the specific capacity is high and is 145-195mAh / g; (3) first coulombic efficiency gt; 80%.

The present invention provides a power-generating cloth based on friction power generation and a preparation method thereof, wherein the power-generating cloth comprises a first friction component and a second friction component, wherein the friction between the first friction component and the second friction component realizes power generation based on friction, wherein the first friction component comprises: a belt-shaped fabric composite layer, a conductive fabric layer and a ring-shaped fabric composite layer, wherein the belt-shaped fabric composite layer and the conductive fabric layer are stacked in parallel, and the ring-shaped fabric composite layer surrounds the outer periphery of the parallel stacked belt-shaped fabric composite layer and the conductive fabric layer. The present invention belongs to green, clean and renewable energy conversion technology. The power-generating cloth of the present invention has high elasticity, high flexibility, high flame retardancy and washability. The power-generating cloth of the present invention can convert various mechanical energies into electrical energy, and improves the conversion efficiency, reducing resource waste to a certain extent.