232 results about "Nitrocellulose" patented technology

The invention discloses a porcine delta coronavirus monoclonal antibody and application thereof in preparation of an antigen detection test strip. The detection test strip comprises a polyvinyl chloride bottom plate on the lowest layer, and a sample pad, a conjugate pad, a nitrocellulose membrane and a water absorption pad are sequentially laid on the polyvinyl chloride bottom plate in the flowing direction; the sample pad is partially overlapped on the combination pad, and the combination pad and the water absorption pad are respectively overlapped on two sides of the nitrocellulose membrane; a detection line and a quality control line are arranged on the nitrocellulose membrane along the flowing direction; an antibody marked by red latex microspheres is sprayed on the combination pad, a coated antibody is sprayed on the detection line, and coated commercial goat anti-mouse IgG is sprayed on the quality control line. The test strip adopts a double-antibody sandwich method for detection, and has the advantages of high detection speed, high sensitivity, strong specificity and the like. The detection result is visual, clear and easy to interpret; the detection process does not need any instrument and equipment, operators do not need professional training, operation is easy and convenient, and the method is particularly suitable for on-site rapid diagnosis.

The invention relates to the technical field of microorganism test paper preparation, in particular to test paper for rapidly detecting microorganisms and a preparation method thereof.The method includes the steps that a combination pad used for fixing color microspheres is pasted to one end of a nitrocellulose membrane, the pasted combination pad is rolled, and a plurality of frames of contour images of overlapped areas are obtained; determining a rebound coefficient according to the comparison condition of different frame contour images so as to judge whether there is an abnormal fitting risk, determining fitting characterization parameters according to the contour image of the feature frame in the preset acquisition period so as to determine the spraying abnormality category of the overlapping region, selecting a spraying adjustment mode of the color microspheres according to the spraying abnormality category, and adjusting the color microspheres according to the spraying adjustment mode. And the sample pad and the water absorption pad are connected with the nitrocellulose membrane and the combination pad to prepare the target test paper, so that the rapid identification of the abnormal fitting risk tendency of the nitrocellulose membrane and the adaptive adjustment of the spraying mode of the color microspheres are realized, and the preparation reliability of the detection test paper is improved.

The invention discloses a preparation method and application of an HPV16 / 18 type E6 / E7 protein multi-target detection test strip, and belongs to the technical field of biological immunodetection analysis. The detection test strip comprises a back plate, a sample pad, a combination pad, a nitrocellulose membrane and an absorption pad, AIE fluorescent microsphere labeled probes are distributed on the combination pad, and a capture antibody and an AIE solution are distributed on the nitrocellulose membrane. The preparation method comprises the following three steps: preparation of the nitrocellulose membrane, preparation of the combination pad and assembly of the test strip. The detection test strip can synchronously and quantitatively detect PV16 E6, HPV16 E7, HPV18 E6 and HPV18 E7, each target corresponds to four signal points, multi-target synchronous rapid detection is achieved, the linear range is wide, the detection limit is low, operation is easy and convenient, cost is low, and the detection test strip is expected to become a novel efficient and reliable on-site screening tool for cervical cancer and precancerous lesions.

A qualitative or quantitative test method to detect a substance to be detected contained in a specimen, the test method including a preparation step of preparing a test sample from the specimen, and a test step of testing at least part of the test sample with a reagent to detect each of a first substance to be detected and a second substance to be detected, in which the first substance to be detected has an isoelectric point of 10.0 or more, and in any one or both of the preparation step and the test step, the first substance to be detected is brought into contact with any one or both of a glass-made member and a nitrocellulose-made member in the presence of a cationic substance. In this test method, two or more substances to be detected including a substance having an isoelectric point of 10.0 or more can be detected with high sensitivity using the same specimen while suppressing a decrease in measurement sensitivity.

The invention discloses an MOFs (Metal-Organic Frameworks) derived bimetallic mesoporous Cu / Ni-MNC (Metal Nitrocellulose) material and a preparation method thereof. The method comprises the following steps: adding a metal salt mixed solution into an organic ligand solution, standing, centrifuging and drying to obtain a Cu / Ni-ZIF material; the preparation method comprises the following steps: adding a Cu / Ni-ZIF-TA material into ethanol, then adding a methanol solution of tannic acid, stirring at room temperature for different times, centrifuging and drying to obtain a Cu / Ni-ZIF-TA material; and the Cu / Ni-ZIF-TA material is calcined, and the bimetallic mesoporous Cu / Ni-MNC material is obtained. Compared with a traditional synthesis template method, an activation method and the like, the method is easy and convenient to operate, safe and environmentally friendly; on one hand, due to introduction of low-boiling-point Zn, agglomeration of nanoparticles at high temperature is inhibited, and on the other hand, etching treatment of tannic acid and nitrogen doping enable the material to have different degrees of defects. The material shows excellent catalytic performance in hydrogenation reduction reaction of furfural, and has a good application prospect.

The utility model discloses nitrocotton alcohol-based solid alcohol automatic production equipment which comprises an alcohol storage tank, an outlet of the alcohol storage tank is connected with an inlet of a stirring reaction kettle through a pipeline, a nitrocotton feeding box is arranged at the top of the stirring reaction kettle, and a gas outlet of the stirring reaction kettle is connected with a gas inlet of a condenser through a pipeline. A reflux inlet of the condenser is connected with an inlet of the crude alcohol metering tank through a pipeline, the crude alcohol metering tank is connected with a reflux inlet of the stirring reaction kettle through a pipeline, and a discharge hole of the stirring reaction kettle is connected with the solid alcohol forming device through a pipeline; according to the utility model, the continuity of the nitrocotton alcohol-based solid alcohol production process is improved, the productivity is greatly improved, all the reaction containers are connected through the pipelines, most of the whole production process is carried out in a closed environment, and the possibility that industrial alcohol is exposed in the environment in the production process is reduced to the greatest extent.

A rapid dual test kit (1) for DHA and EPA detection and method of preparation thereof; that detects DHA and EPA within 0-20 minutes, preferably 1 min; comprising of-a test device (2), a test diluent (29), a dropper (32), a pack insert (33) and a silica gel (34), an immuno-chromatographic strip (3) further comprising of a sample release pad (5), a conjugate pad (6), a nitrocellulose membrane (7), and an absorbent pad (8) arranged in a sequential overlapping manner over a backing material (4); encased in a test device (2) consisting of three open areas namely a sample port (11), test line viewing area (30), and control line viewing area (31); allowing lateral flow of sample (29) from sample release pad (5) to absorbent pad (8) via capillary action; and the method of preparation of kit is disclosed.

The present invention relates to the technical field of the detection of ancient silk fabrics, and discloses a preparation method and application of an immunomagnetic bead test strip for rapidly detecting trace proteins in cultural relics, comprising the following steps: (1) after the carboxyl magnetic beads are subjected to a coupling reaction with protein antibodies, the supernatant is removed by magnetic separation, and after washing with a buffer solution and a cleaning agent in sequence, immunomagnetic beads are obtained; (2) the immunomagnetic beads are sprayed on a pretreated nitrocellulose membrane, and after drying, they are reserved for use; the diluted antibody solution I and antibody solution II are respectively sprayed on the test line and the quality control line of the nitrocellulose membrane, and after drying, they are reserved for use; (3) a sample pad, an immunomagnetic bead conjugate pad, a nitrocellulose membrane and a water absorption pad are assembled and cut in sequence to obtain an immunomagnetic bead test strip, which is stored in a dry and sealed manner. The present invention can achieve rapid and sensitive detection while enriching trace proteins, is convenient for operation at the archaeological site, and takes a short time.

This utility model discloses a concentration device for the production of nitrocellulose, including a tank and an annular frame. An annular groove is formed on the inner wall of the annular frame, and a cross is rotatably connected to the inner side of the annular groove. A barrier frame is fixedly connected to the bottom of the cross, and a barrier net is fixedly connected between adjacent support members of the barrier frame. Two opposing lifting grooves are formed on the inner wall of the tank. Slider blocks are fixedly connected to the outer surfaces of both sides of the annular groove, and the two sliders are located inside the two lifting grooves and slidably connected to them. This utility model uses the barrier frame and barrier net to separate the material, thereby preventing the material from being carried out during liquid extraction, which could lead to blockage and material reduction, thus improving concentration efficiency.

This invention discloses a quantitative test strip for HBV PreS1 antibody based on the AIE molecule, its preparation method, and its applications, relating to the fields of molecular biology, immunology, and biodetection technology. The test strip includes a sample pad, a labeling pad, a nitrocellulose membrane (NC membrane), an absorbent pad, and a base plate. The NC membrane detection line is coated with HBV PreS1 antigen to capture PreS1 antibodies in the sample. The labeling pad contains an immobilized Anti-Human IgG antibody conjugated to the AIE molecule, which binds to the PreS1 antibodies in the sample to form an immune complex. The test strip of this invention enables rapid detection of PreS1 antibodies and achieves enhanced fluorescence in the detection results. Combined with a fluorescence reader or fluorescence card reader, the detection results can be digitally and quantitatively analyzed. It is simple to operate, rapid in detection, and significantly improves detection sensitivity and enables quantitative analysis.

The present disclosure discloses a detection kit and a preparation method thereof and a detection method for novel coronavirus, and relates to the technical field of biomedicine, including an antigen test strip. The antigen test strip includes a substrate, bibulous paper, immune nitrocellulose membrane, and immune microsphere pad. The immune microsphere pad, the immune nitrocellulose membrane and the bibulous paper are pasted on the substrate. The immune microsphere pad is coated with latex microsphere-labeled novel coronavirus SARS-CoV-2 monoclonal antibody 1. The immune nitrocellulose membrane is provided with a test line coated with novel coronavirus SARS-CoV-2 monoclonal antibody 2 and a quality control line coated with goat anti-mouse IgG polyclonal antibody. The present disclosure uses latex particles as labeled tracer, and uses antigen-antibody reaction and lateral chromatography to detect and analyze targets, having advantages of convenience and swift.

The invention belongs to the technical field of chemical engineering, and relates to a composition for a detonation sound agent, the detonation sound agent and a preparation method and application of the detonation sound agent. The technical problems that in the prior art, pyrotechnic composition and aluminum magnesium alloy powder serve as raw materials, potential safety hazards exist in the preparation and storage process, sulfur dioxide generated after combustion easily forms acid rain, and the detonation sound value does not reach the standard are solved. The invention provides a composition for a detonation sound agent, which comprises the following raw materials: 75-85 wt% of lead tetraoxide, 10-15 wt% of aluminum-silicon alloy powder and 5-10 wt% of nitrocellulose gum solution, and has the effects of high detonation sound value, high stability and safety, and suitability for large-scale industrial production and use. The invention further provides a detonation sound agent and a preparation method of the detonation sound agent. Meanwhile, the invention further provides application of the detonation sound agent in preparation of the bird repelling bomb, when the explosive quantity is 300 mg, the set-off sound level value at the position 2 m away from the acting position can reach 120 dB or above, and the good high-altitude bird repelling effect is achieved.

A rapid test kit for Omega-3 fatty acid molecule detection and method of preparation thereof; for detection of DHA or EPA within one minute; comprising of - an immunochromatographic strip (3) further comprising of a sample release pad (5), a conjugate pad ( 6), a nitrocellulose membrane, and an absorbent pad, arranged in a sequential overlapping manner over a backing material; encased in a cassette (2) consisting of three open areas namely a sample port (11), test line viewing area (12), and control line viewing area; allowing lateral flow of sample from sample release pad (5) to absorbent pad via capillary action; and the method of preparation of kit includes steps of; cutting, coating of various pads and nitrocellulose membrane, preparation of capture and detector antibodies, lamination of plastic pad, assembly of cut laminates in cassettes, packing, sealing, preparing, dispensing test diluent into dropper bottle, packing sealed pouches and diluent bottles in boxes.

This invention relates to the field of biodetection technology, and more particularly to a fluorescent test strip for detecting canine parvovirus, along with hybridoma cells, monoclonal antibodies, and their applications. The test strip of this invention has fluorescent microspheres coated with canine parvovirus monoclonal antibody and fluorescently labeled rabbit IgG within the conjugate pad; a detection line and a control line are disposed on the surface of a nitrocellulose membrane, with the detection line coated with canine parvovirus monoclonal antibody and the control line coated with rabbit anti-IgG; wherein the canine parvovirus monoclonal antibody is secreted using hybridoma cells with accession number C202355. The test strip of this invention can be used to simultaneously detect feline parvovirus, canine parvovirus, and various genotypes of canine parvovirus, exhibiting high sensitivity and specificity, and possessing the technical advantages of accuracy, speed, and simplicity.

The centrifugal machine for nitrocellulose comprises a bottom plate, supporting assemblies are symmetrically arranged on the upper portion of the bottom plate, the two supporting assemblies comprise positioning plates, round penetrating holes are correspondingly formed in the two positioning plates, fixing cylinders are arranged on the inner side walls of the two round penetrating holes, and square grooves are formed in the upper portions of the fixing cylinders. A mounting box is arranged at the position, corresponding to the square groove, of the upper portion of the fixing cylinder, a rotating rod is rotationally connected into the mounting box through a bearing, a plurality of fixing plates are arranged on the outer side wall of the rotating rod, a brush is arranged on the outer side wall of each fixing plate, and the arranged fixing cylinder can be matched with the mounting box so that the rotating rod can be supported; the rotating rod can rotate on the rotating rod, so that the multiple groups of brushes can be mounted on the rotating rod through the fixing plate, the outer side wall of the centrifugal barrel can be brushed through the multiple groups of brushes when the centrifugal barrel rotates at a high speed, and the filtering holes of the centrifugal barrel are prevented from being blocked.

The present application relates to the technical field of light polyurethane varnish, especially to the field of IPC C09D175 / 175, more particularly to a clear finish for home products, a preparation method and application thereof. The components include: A component and B component, the weight ratio between the A component and the B component is 1:(0.3-0.6); the A component, by weight percentage, the raw materials include: 50-70% alkyd resin, 1-15% nitrocellulose, 1-5% polyamide wax, 1-5% additives, 3-8% matting powder, and the first solvent makes up the balance; the B component, by weight percentage, the raw materials include: 50-90% TDI curing agent, 0.1-2% dehydrating agent, and the second solvent makes up the balance. The short oil alkyd resin is used in combination with 3106-B-70 and 33089 from Changxing Chemical Industry, which can effectively solve the problem of large difference between positive and negative gloss in the actual production process.

The present invention belongs to the field of chemical coatings, and in particular to a polyurethane net odor high-transparency full matte skin feeling clear surface coating material and preparation method. The material is prepared by evenly allocating a main agent, a curing agent and a diluent by weight ratio; by weight, the main agent is prepared by the following raw materials: 35-55 parts of alkyd resin, 10-25 parts of adipic acid polyester polyol resin, 1-10 parts of butyl acetate, 3-8 parts of ethyl acetate, 5-20 parts of nitrocellulose, 7-15 parts of organic matting powder, 0.1-0.5 parts of defoaming agent, 0.3-1 parts of dispersant, 1-5 parts of anti-settling agent and 0.1-0.5 parts of leveling agent. The present invention is based on adipic acid polyester polyol resin as the main body, and the skin feeling effect achieved by collocation of part of the leveling agent is better and more unique than conventional clear topcoat feel, and the skin feeling effect is permanent, and adipic acid polyester can also react with alkyd resin to form a tight three-dimensional grid structure, thereby improving the adhesion and chemical resistance of the coating.

The utility model discloses a fluorescent quantitative rapid detection card for ofloxacin quantum dot microspheres. The ofloxacin quantum dot microsphere fluorescent quantitative rapid detection card comprises a test strip, the test strip comprises a bottom plate, a sample pad, a fluorescent microsphere conjugate pad, a nitrocellulose membrane and a water absorption pad, the sample pad, the fluorescent microsphere conjugate pad, the nitrocellulose membrane and the water absorption pad are arranged on the bottom plate and connected in sequence, and detection lines and quality control lines which are distributed at intervals are arranged on the nitrocellulose membrane. The detection line is close to the fluorescent microsphere conjugate pad, the quality control line is close to the water absorption pad, the detection line is coated with a micromolecule ofloxacin antigen, the quality control line is coated with a goat anti-mouse IgG antibody, and a microsphere labeled antibody conjugate in the fluorescent microsphere conjugate pad is a fluorescent microsphere labeled ofloxacin antibody. The method is simple and rapid to operate, is less affected by environment temperature and solvent reagents, is suitable for rapid detection of food safety, and is accurate in detection result.

The utility model relates to the technical field of alcohol recovery devices for nitrocellulose production, in particular to a portable low-concentration alcohol recovery device which can effectively prevent a distillation tank from colliding with a box body when the distillation tank is taken and placed, so that the distillation tank is more convenient to take and place, convenience is brought to workers, and the practicability is improved. Comprising a box body, four sets of universal wheels are fixedly installed at the bottom end of the box body, a taking and placing opening is formed in the front end of the box body, a box door covers the taking and placing opening in a rotating mode through hinges, a motor is fixedly installed at the position, close to the rear portion, of the right end of the box body, a push plate is fixedly connected to the rear sides of the top ends of two sets of T-shaped bearing rods, and the bottom end of the push plate makes contact with the top end of a supporting plate. Two sets of hinge seats are symmetrically and fixedly arranged at the rear end of the push plate, two sets of hinge seats are also fixedly arranged on the two sets of transmission threaded sleeves, two sets of transmission battens are symmetrically hinged to the rear end of the push plate through the two sets of hinge seats, and the front ends of the two sets of transmission battens are hinged to the hinge seats on the two sets of transmission threaded sleeves respectively.

The invention discloses a micro gas generator homogeneous mixed medicament for a safety belt and a preparation method of the micro gas generator homogeneous mixed medicament, the micro gas generator homogeneous mixed medicament is prepared from the following components in percentage by mass: 90-97% of green gas generating medicament particles and 3-10% of nitrocellulose medicament particles uniformly dispersed in gaps of the green gas generating medicament particles, and the sum of the mass percentages of the components is 100%. By utilizing the advantages of high combustion speed and low ignition threshold of the nitrocellulose agent, the ignition delay and the combustion period of the mixed agent are shortened, the exposure time of the safety belt elbow in a high-temperature environment is shortened, the structural strength of the safety belt elbow is ensured, the problem of elbow explosion in a bonfire test is finally solved, and meanwhile, the environment-friendly characteristic of a green gas-producing agent is reserved; in addition, through the two-time charging process of the automatic production line, the mixed charging efficiency is high, and the product consistency is good.

The utility model provides a rapid detection kit for synchronously detecting cell factors IFN-gamma and TNF-alpha, comprising: a kit body comprising a card box and a box cover which covers the bottom of the card box; the detection card is arranged in the card box; the liquid suction device is connected with the detection card and extends out of the card box, and the box cover hermetically wraps the sample suction device; the detection card comprises a bottom plate and test strips adhered to the bottom plate, and the test strips comprise a first test strip and a second test strip which are symmetrically arranged on the two sides of the surface of the bottom plate; the first test strip comprises a sample pad, a first latex microsphere pad, a first nitrocellulose membrane and absorbent paper which are sequentially lapped; the second test strip comprises a sample pad, a second latex microsphere pad, a second nitrocellulose membrane and absorbent paper which are sequentially lapped. The kit is simple in structure, the kit comprises the two detection cards in parallel, IFN-gamma and TNF-alpha can be synchronously detected at a time, manpower and material resources are greatly saved, and operation is easy and fast.

The invention provides a progesterone detection reagent strip based on an antibody synergistic effect and a preparation method of the progesterone detection reagent strip. The progesterone detection reagent strip comprises a bottom plate, a sample pad, a combination pad, a nitrocellulose membrane and a water absorption pad, the combination pad is sprayed with fluorescent nano-microspheres coupled with a goat-derived PROG antibody and fluorescent nano-microspheres coupled with a goat anti-rabbit antibody, a detection line of the nitrocellulose membrane is coated with a PROG antigen, and a quality control line of the nitrocellulose membrane is coated with a rabbit anti-goat IgG antibody. According to the progesterone detection reagent strip based on the antibody synergistic effect, the competition method detection principle is adopted, the fluorescent microspheres are used as markers, the progesterone antibody and the fluorescent microspheres are combined in a coupling mode, the specificity and binding efficiency of antigen-antibody reaction are optimized based on the antibody synergistic effect, and the progesterone detection reagent strip can be used for detecting progesterone. The stability and sensitivity of the detection system are remarkably improved, and high-sensitivity and high-specificity detection of the progesterone level in serum or plasma is achieved.

The utility model discloses a detection kit for rapidly detecting chicken, duck and pork mixed in beef and mutton. The detection kit comprises a detection card and a plastic card, the detection card is formed by sequentially lining absorbent paper and a sample pad below a nitrocellulose membrane, cutting the nitrocellulose membrane into test strips, and packaging the test strips in the plastic card; due to the fact that specific species antibodies of chickens, ducks and pigs are preset in the detection kit, chicken, duck or pork components which are as low as 3% and mixed in milligram-level samples can be sensitively detected at a time through antigen-antibody reaction.

The application discloses a preparation method and application of an HPV16 / 18 type E6 / E7 protein multi-target detection test strip, and belongs to the technical field of biological immune detection and analysis. The test strip comprises a back plate, a sample pad, a combination pad, a nitrocellulose membrane and an absorption pad, AIE fluorescent microsphere labeled probes are distributed on the combination pad, and capture antibodies and AIE solution are distributed on the nitrocellulose membrane. The preparation method comprises three steps of preparation of the nitrocellulose membrane, preparation of the combination pad and assembly of the test strip. The test strip can quantitatively detect PV16 E6, HPV16 E7, HPV18 E6 and HPV18 E7 simultaneously, four signal points correspond to each target, multi-target synchronous rapid detection is realized, the linear range is wide, the detection limit is low, the operation is simple and convenient, the cost is low, and the test strip is expected to become a new tool for efficient and reliable on-site screening of cervical cancer and precancerous lesions.

The invention discloses a preparation method and application of a clothianidin fluorescent test strip, belongs to the technical field of agricultural detection, and solves the problems that the existing bombyx mori pesticide poisoning detection sensitivity is low, and the clothianidin residue concentration cannot be quickly judged. According to the method, a nitrocellulose membrane is prepared, a detection line is coated with a clothianidin-BSA antigen, and a quality control line is coated with an anti-mouse IgG antibody; when the fluorescent pad is prepared, carboxylated fluorescent microspheres and an anti-clothianidin antibody are coupled to form a labeled probe; when the test strip is assembled, the nitrocellulose membrane, the fluorescent pad, the sample pad and the absorbent paper are stacked and fixed on the bottom plate to form a chromatography structure. Clothianidin in a sample is combined with the labeled probe to form an immune complex, chromatography migrates to the detection line to be competitively combined with clothianidin-BSA antigen, the uncombined probe is captured and develops color, and the quality control line develops color through an anti-mouse IgG antibody. The test strip is used for rapidly detecting clothianidin residues in mulberry leaves and bombyx mori bodies, the sensitivity reaches 0.02 mg / L, pesticide poisoning events can be effectively prevented, and safe production of the sericulture industry is guaranteed.

To provide a printing ink composition for surface printing, which can form a printing layer having excellent adhesion to a substrate and excellent resistance to heat yellowing, even when the substrate is a polyethylene film that has not been subjected to corona discharge treatment. [Solution] A printing ink composition for surface printing, comprising a binder resin (A), a terpene resin (B), and an organic solvent, wherein the binder resin (A) comprises a nitrocellulose resin (A1) and a polyurethane resin (A2), the terpene resin (B) has a solubility parameter calculated by the Fedors method of 10.0 or less and a softening point of 90°C or more, and the content of the terpene resin (B) converted to solid content is 2 to 25 mass% relative to the total mass of the solid content of the printing ink composition for surface printing.

This application relates to the field of packaging paper technology, specifically to a flame-retardant cigarette tipping paper, comprising a substrate and a color layer and a flame-retardant layer laminated on the surface of the substrate; wherein, the flame-retardant layer comprises an electroplated aluminum layer and / or a metallic ink layer; the flame-retardant layer completely covers the color layer, or the flame-retardant layer partially covers the color layer in a strip shape with the covered portion close to the end of the flame-retardant cigarette tipping paper used for connecting with the cigarette, and the total width of the flame-retardant layer is ≥4mm; by mass percentage, the raw materials of the metallic ink layer include the following components: 7%–12% nitrocellulose resin, 4%–8% flame-retardant resin, 10%–20% metallic pigment, and 0.5%–2% additives, with the balance being solvent; the printing transfer amount of the metallic ink on the color layer is 1.5g / m 2 ~2.0g / m 2 The flame-retardant cigarette tipping paper provided in this application has a good flame-retardant effect; and the subsequent decoration process does not require additional color sequence, which can reduce production costs.

Lateral flow immunoassay systems include test strips having unique geometries to enhance fluid dynamics, including but not limited to: (1) conjugate pads having sinusoidal, meandering, and nozzle-diffuser patterns; and (2) nitrocellulose membrane pads having constriction zones corresponding to the location of T-lines and / or C-lines. The systems can further include a cartridge with a two-step rotation mechanism for contamination-free sample delivery to the sample pad of a test strip, and an AI-based detection system for quantifying the concentration of a detected analyte based on colorimetric signal intensities. The system exhibits improved analyte sensitivity over prior systems, reduces traditional assay time, eliminates subjective interpretation of colorimetric signal intensities, and quantifies analyte concentration levels.

The invention relates to the technical field of non-invasive glycosylated hemoglobin detection, and discloses non-invasive glycosylated hemoglobin detection test paper and method.The non-invasive glycosylated hemoglobin detection test paper comprises a sampling layer, a combination cushion layer is bonded to the lower surface of the sampling layer, and a nitrocellulose membrane layer is bonded to the side face, away from the sampling layer, of the combination cushion layer; a water absorption layer is adhered to one side surface, far away from the combined cushion layer, of the nitrocellulose membrane layer; a PVC bottom plate is adhered to one side surface, far away from the nitrocellulose membrane layer, of the water absorption layer; through cooperation of the structures, the pain feeling during sampling can be reduced, and the tissue fluid collecting efficiency is improved.

The invention discloses a test strip biosensor for detecting uranyl ions, the test strip biosensor comprises a reaction system and a test strip, the reaction system comprises a DNAzyme substrate chain and a DNAzyme enzyme chain; the test strip comprises a substrate, a sample pad, a coupling pad, a nitrocellulose membrane and an absorption pad, the sample pad, the coupling pad, the nitrocellulose membrane and the absorption pad are sequentially overlapped on the substrate, a gold nanoparticle-DNA probe I compound is fixed on the coupling pad, a test line and a control line are arranged on the nitrocellulose membrane, an SA-biotin-DNA probe II is fixed on the test line, and an SA-biotin-DNA probe II is fixed on the control line. And an SA-biotin-DNA probe III is fixed on the control line. Compared with the prior art, the biosensor can realize high-sensitivity and high-specificity detection of uranyl ions by integrating a DNA enzyme induced cleavage reaction and a gold nanoparticle mediated colorimetric detection technology, the detection process is simple and rapid, and an important technical support is provided for field monitoring of UO2 < 2 + > in environment and biological samples.