77 results about "Gold particles" patented technology

The invention relates to the technical field of semiconductors, in particular to a gallium oxide nanowire / porous gallium nitride heterojunction and a preparation method and application thereof. The method comprises the following steps: sequentially growing a GaN buffer layer, a u-GaN layer and a p-GaN layer on a substrate to obtain a base; in mixed gas of hydrogen and inert gas, performing thermal decomposition on the substrate to obtain porous gallium nitride; heating the porous gallium nitride in mixed gas of oxygen and inert gas to obtain a gallium oxide / porous gallium nitride heterojunction; spraying gold on the surface of the gallium oxide / porous gallium nitride heterojunction, and annealing the gold into gold particles in an inert atmosphere; in mixed gas of oxygen and inert gas, a gallium source is arranged beside the gallium oxide layer in the previous step for heating, and the gallium oxide nanowire / porous gallium nitride heterojunction is obtained. The prepared heterojunction has excellent carrier transport characteristics, light absorption efficiency and charge separation capability, and is suitable for the fields of solar-blind ultraviolet photoelectric detection, photocatalysis, high-sensitivity sensors, high-power electronic devices and the like.

This invention discloses a functionalized biomodified electrode for rapid pathogen detection and its preparation method, relating to the fields of biosensing and electrochemical detection technology. It includes a glassy carbon electrode substrate, the surface of which is sequentially modified with a reduced graphene oxide layer, an electropolymerized polydopamine film, and an electrodeposited gold nanoparticle layer, forming a composite nanomaterial modified electrode. Antibodies are captured and fixed to the electrode surface through covalent interactions. This functionalized biomodified electrode for rapid pathogen detection and its preparation method, using the same electrochemical workstation, first electropolymerizes dopamine to form a film and then electrodeposits gold nanoparticles. This allows for precise control of film thickness, gold particle size, and coverage density by parameters such as polymerization potential, scan cycles, deposition potential, and deposition time. This avoids batch-to-batch fluctuations caused by dissolved oxygen and solution disturbances in traditional chemical methods, reducing the relative standard deviation of peak current detection from different batches of electrodes from 18.7% to 4.2%–4.5%.

The invention belongs to the technical field of harmful microorganism detection, and particularly provides an electrochemical sensor for detecting escherichia coli (escherichia coli O157: H7) in food and a preparation method of the electrochemical sensor. According to the electrochemical sensor, the surface of a substrate electrode is sequentially modified with an electron transduction layer and a recognition molecular layer; wherein the electron transduction layer is formed by an infinite coordination polymer composite material of gold nanoparticles; the recognition molecular layer is a nucleic acid aptamer. The electrochemical sensor is high in sensitivity, good in selectivity and low in detection limit; compared with other detection methods, the method does not need incubation and can be directly used for in-situ and rapid detection of bacteria.

The application discloses a kind of electron microscope colloidal gold label aggregation degree quantitative analysis method, including obtaining transmission electron microscope colloidal gold label picture, then the electron microscope colloidal gold label picture is pretreated, for the picture after pretreatment parameter-dependent semi-automatic division gold particle and manually selected region of interest, then the area density of real gold particle in region of interest is calculated, the aggregation degree of gold particle is calculated using average nearest neighbor analysis method to electron microscope colloidal gold in the range of 60-140 area density, finally identify ANNA numerical value between 0.6-1.4 electron microscope colloidal gold is labeled as qualified positive marker data.The application selects suitable gold particle positive marker data by the calculation of gold particle area density and aggregation degree, eliminates the interference of false positive to ANNA quantitative analysis, so that average nearest neighbor analysis method can be suitable for electron microscope colloidal gold label scene quantitative analysis.

The catalyst for the oxidative esterification of methacrolein to methyl methacrylate comprises a support having an average diameter of at least 0.8 mm. The support is selected from oxides of silicon, carbides of silicon, metal oxides, and metal carbides. The catalyst further comprises nickel oxide and gold particles disposed on the support. The gold particles have an average diameter of less than 12 nm and a standard deviation of + / - 4 nm. A process for preparing methyl methacrylate from methacrolein and methanol using the catalyst is also disclosed.

The invention discloses a technology for improving the leaching rate of micro-fine particle wrapped gold based on microwave and oxidizing agent combined pretreatment, and belongs to the technical field of gold extraction metallurgy. The process comprises the steps of ore pulp pretreatment, concentration and pulp mixing, composite oxidizing agent adding, microwave pretreatment, cyanidation leaching and the like. According to the method, the microwaves and the composite oxidizing agent are utilized, a microfine particle gold wrapping carrier is efficiently destroyed, the leaching rate of gold is increased to 85-92% from 45-55% of a traditional method, meanwhile, energy consumption is reduced by 40% or above, sulfur dioxide emission is avoided, and the method has the advantages of being efficient, low in consumption, environmentally friendly and the like and is particularly suitable for extraction of arsenic-containing, sulfur-containing, carbon-containing and other microfine particle wrapping type refractory gold ores.

The application discloses a small-molecule multi-connection detection kit based on a biochip, a preparation method and a detection method thereof. The kit comprises nano-gold particle labeled antibodies, a multi-connection detection chip plate and a detection buffer. The nano-gold particle labeled antibodies comprise nano-gold particle labeled florfenicol antibodies and enrofloxacin antibodies. The multi-connection detection chip plate is coated with florfenicol antigens and enrofloxacin antigens in detection holes. The detection buffer is composed of 10-40 mM phosphate buffer and 0.05-0.5 wt% surfactant S17. The application can simultaneously detect florfenicol and enrofloxacin small molecules by using one detection buffer, thereby saving time and labor.

The invention discloses a zinc oxide nano sound-sensitive agent as well as a preparation method and application thereof, and belongs to the technical field of sound-sensitive agents. The zinc oxide nano sound-sensitive agent prepared by the invention comprises composite zinc oxide and a mesoporous silicon dioxide layer with glutathione responsiveness from inside to outside; the mesoporous silica layer with glutathione responsiveness is subjected to hydrothermal treatment after being aminated and is modified with hyaluronic acid; the composite zinc oxide is obtained by depositing nano gold particles on the surface of zinc oxide after carbon doping; the zinc oxide nano sonosensitizer prepared by the method is relatively good in biological safety, has better sonodynamic activity and can efficiently generate active oxygen.

The application relates to a kidney-excretable nano-gold aggregate, a preparation method and application as a CT contrast agent, and comprises the following steps: mixing chloroauric acid solution, lye and a mercapto hydrophilic compound to obtain mixed solution A; under the condition of ice water bath and stirring, a reducing agent is added into the mixed solution A to obtain mixed solution B containing nano-gold particles; the mixed solution B is mixed with a wrapping material-buffer solution to obtain mixed solution C containing nano-gold particles@wrapping material; a positively charged compound solution is added into the mixed solution C to obtain mixed solution D; the nano-gold is made into a stable aggregate by the positively charged compound; and the mixed solution D is centrifuged to obtain the kidney-excretable nano-gold aggregate. The synthesized super-small nano-gold is agglomerated into a nano-gold aggregate with stable structure, and the contrast agent can be obtained by simple centrifugal concentration, the contrast agent is stable in property, has good biocompatibility, and can be discharged out of the body along with urine within a period of time after entering the body.

This invention belongs to the field of battery technology. It provides a pre-lithiation separator, its preparation method, and its applications. The pre-lithiation separator includes a separator substrate with a coating. The coating includes a lithiophilic material, a reinforcing material, and a binder. The lithiophilic material includes at least one of copper oxide particles, graphene, silver particles, or gold particles. The reinforcing material includes inorganic non-metallic particles. A lithium metal layer is disposed on the side of the coating away from the separator substrate. The lithiophilic material has a strong affinity for lithium, promoting uniform lithium deposition and enhancing the binding between the separator and lithium. The reinforcing material enhances the heat resistance and mechanical properties of the separator, resisting damage to the separator during the preparation of the lithium metal layer. By setting this specific coating, the lithium uniformity of the pre-lithiation separator can be fundamentally improved, thereby enhancing the mechanical properties and heat resistance of the pre-lithiation separator, which is beneficial for further improving battery performance.

The invention provides a laboratory column leaching method, and belongs to the technical field of hydrometallurgy. According to the method, interference of fine-grained materials and coarse-grained gold on leaching is effectively eliminated through rigorous particle size separation and pretreatment steps, and the effect that the fine-grained materials are stacked and covered on the surface of deep leached ore along with a leaching agent in the simulated dump leaching process and the pressure borne by the deep ore are combined, so that the leaching efficiency of the deep leached ore is improved. The physical and chemical conditions of the deep ore in the dump leaching process are further simulated, the industrial dump leaching conditions are more truly reduced, the actual leaching rate of elements to be recycled in the ore in the actual dump leaching process is accurately evaluated, production is guided, and scientific data support is provided.

The application relates to a preparation method of modified micron gold dispersion liquid and conductive gold paste. Gold powder is prepared by an in-situ synthesis method, the gold powder is modified by CTAB, the gold is directly transferred into an organic solution by utilizing the different surface tension of the gold particles after surface modification in different solutions, the gold can be directly configured into a slurry, the gold powder can be uniformly dispersed in the slurry without needing to be precipitated, dried and re-dispersed, the problems of uneven dispersion of the gold powder and unstable performance after sintering caused by the precipitation and dispersion in the traditional process are avoided, meanwhile, the yield of the gold powder is higher, and new impurities are avoided in the drying step.

The application relates to the field of gas sensors, and particularly discloses an electrochemical acetylene sensor electrode, a preparation method thereof and an electrochemical acetylene sensor. The electrochemical acetylene sensor electrode comprises a polytetrafluoroethylene film and a slurry coated on the polytetrafluoroethylene film, wherein the slurry comprises nano gold particles, nano magnesium oxide, nano barium oxide, modified conductive carbon powder and a Nafion solution in a weight ratio of (0.47-0.50):(0.02-0.20):(0.02-0.18):(1-3):(0.6-2.0); and the modified conductive carbon powder is obtained by mixing potassium permanganate, deionized water and conductive carbon and then performing ball milling. The application realizes the effects of high sensitivity and high linearity of acetylene gas, greatly improves the selectivity of the electrochemical acetylene sensor, and has the advantages of low detection limit, high sensitivity and good selectivity.

The invention discloses a method for extracting gold through leaching after preoxidation of sulfide gold ore, and aims to solve the problems of low recovery rate, serious environmental pollution and the like of a traditional gold extraction method. The method comprises the following steps: firstly, mixing and finely grinding the gold sulfide ore and caustic soda flakes to 325 meshes, and adjusting the concentration of ore pulp to 33%; then, oxygen-enriched air is introduced into the reaction kettle and heated to 90 DEG C, pre-oxidation treatment is carried out for 18 hours, sulfide minerals are oxidized and decomposed, and gold particles are exposed; then, adding a golden cicada environment-friendly gold extraction agent and activated carbon for leaching, continuously reacting for 18 hours to form a thiosulfate complex of gold, and adsorbing the thiosulfate complex by the activated carbon; and finally, recovering gold by filtering and analyzing electrolytic activated carbon, and performing dry discharge on tailings to prepare bricks. By implementing the method, the leaching recovery rate of gold can be remarkably increased to 97%, meanwhile, cyanide is prevented from being used, environmental pollution is reduced, comprehensive utilization of resources is achieved, and the method has the multiple advantages of being efficient, environmentally friendly, economical and the like.

The present invention relates to a novel liposomal system for incorporating nano-sized edible gold particles into olive oil. This system utilizes liposomes composed of phospholipids and, optionally, cholesterol to encapsulate gold particles within the olive oil, ensuring uniform dispersion and preventing clumping or sedimentation. The liposomal formulation enhances the aesthetic appeal of the oil by maintaining a shimmering effect, and it can be further stabilized with antioxidants to prevent oxidation and prolong shelf life. The invention provides a stable, visually appealing product suitable for use in premium food items, cosmetics, and luxury gift products. Methods for preparing the liposomal system include thin-film hydration, reverse-phase evaporation, and emulsification, each ensuring effective encapsulation of the gold particles. The system is biodegradable and free from synthetic surfactants, aligning with growing demands for natural and sustainable products in the food and cosmetic industries.

The application relates to a nanowire array, a growth method and a thermoelectric device, and the growth method comprises the following steps: obtaining a SnTe template and SnTe powder, taking the SnTe template as a growth substrate, and coating gold particles on the SnTe template; placing the SnTe powder in a high-temperature zone and the SnTe template in a low-temperature zone, heating the SnTe powder in the high-temperature zone to sublimate into a gaseous state, and when the gaseous SnTe flows to the SnTe template in the low-temperature zone, the gaseous SnTe is cooled and grows into SnTe nanowires under the induction of the gold particles, and the SnTe nanowires are nanowires grown along the 100 direction. The growth method utilizes a selective growth mechanism with the lowest energy to obtain a directional and ordered SnTe nanowire array, and the obtained nanowire thermal conductivity can be as low as 5.6 Wm ‑1 K ‑1 .

The invention discloses an FET (Field Effect Transistor) biosensor based on aptamer functionalized carbon nanotubes as well as a preparation method and application of the FET biosensor, and belongs to the technical field of pesticide residue detection. The FET biosensor comprises a chip provided with a conducting channel and an aptamer recognition layer constructed on the chip, according to the chip, a semiconductor single-walled carbon nanotube film sorted by polycarbazole is used as a conducting channel, and gold nanoparticles are synthesized on the surface of the channel in situ; the aptamer recognition layer contains a specific aptamer and is fixed with the nano-gold particles through a gold-sulfur bond. Meanwhile, the invention also provides a preparation method of the FET biosensor. The detection limits of the sensor to chlorpyrifos, isocarbophos and omethoate in a phosphate buffer solution respectively reach 0.51 fM, 0.47 fM and 0.21 fM, the linear detection range is 1 * 10 < M > to 1 * 10 < M >, the adding standard recovery rate is 86-105%, and the variation between the sensors is less than 5%. Specific experiments show that the sensor has no obvious response to non-organophosphorus pesticides.

The invention discloses an antimony-gold concentrate flotation antimony removal process, belongs to the technical field of ore flotation, and aims to solve the technical problem that the gold enrichment performance and antimony removal performance of antimony-gold concentrate flotation need to be further improved in the prior art. According to the method, a step-by-step interface regulation and control system composed of an arsenic directional collecting agent, an antimony selective collecting agent and a lead chelating dispersing agent is constructed, and interface substrate reforming, target phase interface recognition strengthening and terminal interface convergence are sequentially achieved in ore pulp, so that a flotation layering environment with gradient selectivity is formed; according to the technical scheme, the interface stability of associated impurities such as arsenic, antimony and lead can be weakened step by step while interface activation of gold particles is kept, and efficient purification of refractory gold concentrate is achieved.

The invention provides a sensor for multichannel respiratory virus impedance detection and a detection method thereof. The synchronous detection of four respiratory viruses by the single-electrode chip is realized by electrodepositing nano-gold particles on the surface of a screen-printed carbon electrode and constructing a carboxyl self-assembled single layer, and fixing different virus specific antibodies on the surfaces of different working electrodes by adopting EDC / NHS (Ethylene Diamine Chloride / N-Hydroxysuccinimide). And recording an electrochemical impedance spectrum by using a red oxidation-reduction probe, and carrying out quantitative analysis based on total impedance change. The method has the advantages of high sensitivity, strong specificity, short detection period, low cost, suitability for on-site rapid screening and the like.

The application provides an immunocolloidal gold electron microscope detection method based on Spurr embedding plant tissue samples and ultrathin sections, and belongs to the technical field of plant tissue embedding. The application provides application of Spurr as an embedding agent of plant tissues to ultrathin sections in immunocolloidal gold electron microscope detection. In the immunocolloidal gold electron microscope detection provided by the application, the plant tissues are embedded by using the Spurr embedding agent, plant tissue ultrathin sections are obtained, and then the plant tissue ultrathin sections are treated by using an immunocolloidal gold labeling method and then detected, so that a detection result with clear virus morphology and cell ultrastructure and high gold particle contrast can be obtained, and false positives are not prone to occurring in the detection result.

This invention provides an automatic gold enrichment device for placer gold flow channels, belonging to the field of mining machinery technology. The device includes a support mechanism, a posture adjustment mechanism, a feeding mechanism, and multi-stage enrichment units. The feeding mechanism is mounted on the support mechanism, and a gold-adhesive conveyor belt is installed in a counter-rotating manner within its feeding trough. The multi-stage enrichment units are arranged sequentially along the slurry flow direction, including a material distribution mechanism, a vortex generating mechanism, a vibration settling mechanism, and an automatic material collection mechanism. This invention achieves continuous enrichment and automatic material collection without stopping the machine by coordinating the counter-rotating gold-adhesive conveyor belt with the automatic material collection mechanism, avoiding production interruptions and manual cleaning. The combination of the vortex generating mechanism to extend the residence time of fine gold particles and the vibration settling mechanism to prevent mud and sand caking and enhance fluidized settling reduces the risk of secondary gold particle loss, improves the efficiency and stability of fine gold recovery, and is suitable for continuous and efficient placer gold enrichment operations under different working conditions.

The invention relates to a high-activity nano-enzyme with rich gold nano-islands and a preparation method and application of the high-activity nano-enzyme. The invention belongs to the technical field of nanomaterials. The preparation method comprises the following steps: preparing a tellurium-selenium nanorod from a tellurium precursor substance, a selenium precursor substance and a reducing agent; and carrying out chemical reaction on the precursor substances of platinum and gold by taking the precursor substances as a chemical template. Wherein after a gold precursor substance is added, a large number of tiny gold particles distributed on the surface of the nanorod like islands are generated through chemical reaction between the gold precursor substance and a template component, so that more modification sites can be provided, the catalytic activity of the material is improved, the distance between a modification substrate and the platinum surface is closer, and efficient catalytic reaction is realized. The problems that in an existing combination mode of the platinum / gold heterostructure, gold particles and platinum particles are connected through a very small number of heterointerfaces, so that modifiers of gold particle parts are possibly far away from platinum particle parts, and catalytic reaction of platinum on the modifiers is not facilitated are solved.

The invention relates to the technical field of nanometer manufacturing and braze coating, in particular to amorphous nanometer alloy particles for braze coating and a preparation method of the amorphous nanometer alloy particles. The preparation method comprises the following steps: S1, adopting a metal salt mixture of at least two different metals as a target material, and loading the target material onto a substrate; s2, adding ionic liquid into the liquid-phase organic medium, and dispersing to obtain a composite medium; s3, immersing the substrate into the composite medium, and irradiating the metal salt by adopting double-pulse femtosecond laser to carry out liquid phase ablation; and S4, a passivating agent is added into the reaction liquid obtained in the step S3, mixing is conducted, solid-liquid separation, washing and drying are conducted, a passive film is formed on the surface of alloy particles, and the amorphous nano-alloy particles are obtained. The method disclosed by the invention is a universal method and is suitable for preparing various multi-component amorphous nano-alloy particles; and the prepared nano alloy particles are high in amorphous state degree and excellent in oxidation resistance.

This invention discloses a pretreatment method for preparing a gold catalyst, the gold catalyst itself, and its applications, belonging to the field of catalyst preparation and application technology. The invention firstly involves preparing a catalyst impregnation solution with gold as the active component and titanium-silicon molecular sieves as the carrier through impregnation. Then, a two-stage freeze-vacuum drying process is used to remove moisture from the catalyst impregnation solution, preventing the migration, reduction, aggregation, and growth of gold species on the catalyst surface under high-temperature air drying conditions. Secondly, a mixture of hydrogen and hydrogen chloride is used to activate the catalyst. Hydrogen primarily serves to transfer heat and inhibit the aggregation and growth of gold particles, while hydrogen chloride primarily activates the gold to its oxidized state. Compared to catalysts obtained through traditional high-temperature drying pretreatment, the catalyst prepared by combining freeze-vacuum drying and two-component gas activation exhibits smaller gold particle sizes and superior activity and stability in the acetylene hydrochlorination reaction to synthesize vinyl chloride.

One aspect according to the present invention relates to: a gold nanozyme including glycol chitosan and gold particles; and a pharmaceutical composition for preventing or treating inflammatory bowel disease, the composition comprising the gold nanozyme. The gold nanozyme and the pharmaceutical composition comprising same according to one aspect of the present invention was found to inhibit the expression of inflammatory factors, inhibit the generation of reactive oxygen species (ROS) and reactive nitrogen species (RNS) inside cells, and reduce the production of nitric oxide (NO) inside cells. In addition, the gold nanozyme was found to inhibit the secretion of Hight Mobility Group Box 1 (HMGB1) when further including glycyrrhizin. In addition, the gold nanozyme and the composition comprising same were found to enable the recovery of the length, weight, etc., of damaged intestines, and thus can be used in the inflammatory bowel disease prevention and / or treatment industry / market.

The invention belongs to the technical field of gastrin detection reagents, and discloses a gastrin chemiluminescence detection kit and a preparation method thereof, the gastrin chemiluminescence detection kit comprises a reagent I and a reagent II, the reagent I is a magnetic bead suspension coated with a G17 antibody 1; and the reagent II is a nano gold particle suspension carrying a nano antibody 2-B-SA-PolyHRP. The preparation method of the gastrin chemiluminescence detection kit comprises the following steps: S1, preparation of a reagent I: adding a G17 antibody 1 into a magnetic bead suspension to prepare a magnetic bead suspension coated with the G17 antibody 1; and S2, preparation of a reagent II: firstly synthesizing nano-gold particles, and then preparing HRP labeled G17 antibody modified nano-gold particles. The kit is simple in component, and based on a double-antibody sandwich method, G17 in a sample is respectively combined with a G17 antibody 1 on the surface of a magnetic bead in the reagent I and a gastrin nano antibody 2-B-SA-PolyHRP on nano gold particles in the reagent II, so that a sandwich structure is formed, and accurate and sensitive detection of gastrin G17 is realized.

The application discloses a low-toxicity and environment-friendly gold beneficiation method, which comprises the following steps: mixing gold ore with water to obtain slurry A, adding sodium citrate into the slurry A to obtain slurry B, grinding the slurry B to obtain slurry C, wherein the particle size of more than 90% of the ore powder particles in the slurry C is 50-100 mu m; adding a flotation agent into the slurry C to obtain rough selected ore, mixing the rough selected ore with water to obtain slurry D, adding ammonia water into the slurry D to adjust the pH value, adding a pretreatment agent into the slurry D to obtain fine selected ore after stirring and filtering, wherein the pretreatment agent comprises sodium persulfate, methyl isobutyl carbinol, low alcohol, sodium dodecyl sulfate and water; mixing the fine selected ore with water to obtain slurry E, adding a composite leaching agent into the slurry E to obtain leaching liquid, and obtaining gold mud from the leaching liquid by using a displacement method. The application solves the problem of difficult exposure of gold particles in the refractory gold ore, and improves the gold extraction efficiency by using the composite environment-friendly gold extraction agent for gold leaching.

The invention discloses a preparation method of a plasmon nanopore array, which comprises the following steps: immersing a substrate sheet in a positively charged silane coupling agent solution, and drying to obtain a first surface; forming a single-layer polymer microsphere colloid on the first surface through self-assembly, and forming to obtain a second surface; removing the silane coupling agent layer, which is not shielded by the microspheres, on the second surface to obtain a third surface; removing the microspheres on the third surface, and exposing the array region covered with the silane coupling agent layer to obtain a fourth surface; the fourth surface is immersed in a gold particle solution containing a protective agent, gold particles are electrostatically adsorbed in the array area, and a fifth surface is obtained; and performing high-temperature annealing on the fifth surface to obtain the plasmon nanopore array. The method provided by the invention is simple in preparation process and controllable in structure, and has wide application prospects in the aspects of life science, medical diagnosis and the like.

The invention discloses preparation and application of an Au / S-1 catalyst for oxidative esterification, the catalyst takes a pure silicon molecular sieve S-1 as a carrier, the hydrophobicity of the carrier can be improved through silanization treatment, and methanol and propionaldehyde are enriched by enhancing the adsorption effect of organic matters and the catalyst, so that the catalytic activity of the catalyst is improved. The interaction between gold and S-1 can be effectively enhanced, the size of the gold nanoparticles is controlled to be 2-5 nm, contact between reactants and active sites is facilitated, and the center utilization rate of gold is increased; meanwhile, a complexing agent is added for modification, a protection effect on the gold particles is achieved, the stability of the gold particles is enhanced, the catalytic activity is improved by modifying the catalyst, and the method has great industrial production value.

Systems and methods for minimally-invasive lipolysis in a target area by injecting the area with a solution of photo-absorbing nanoparticles such as substantially spherical gold nanoshells that may comprise a non-conducting core, and irradiating the injected area with a beam of near infrared (NIR) light adapted to excite the nanoparticles to melt or ablate fat within the target area.