494 results about "Chloroauric acid" patented technology

The invention discloses a core-shell structure Au-coated CeO2 nano-catalyst and a preparation method and application thereof, and belongs to the technical field of core-shell structure catalysts.The preparation method of the catalyst comprises the following steps that S1, a chloroauric acid solution and a low-concentration cerium chloride solution are added into deionized water and stirred and mixed at the temperature of 5 DEG C, then an ammonia water solution is rapidly added, stirring and mixing are conducted at the temperature of 5 DEG C, and a mixed solution is obtained; quickly adding a high-concentration cerium chloride solution, and continuously stirring for 30 minutes to obtain a mixed solution; s2, carrying out centrifugal separation on the mixed solution to retain a precipitate, washing the precipitate with deionized water and absolute ethyl alcohol, and carrying out freeze drying to obtain a catalyst precursor; s3, performing cleaning treatment and annealing treatment on the catalyst precursor, and cooling to room temperature to obtain a core-shell structure Au-coated CeO2 nano-catalyst; when the catalyst is applied to catalytic synthesis of the BODIPY fluorescent dye, excellent catalytic performance and recycling performance are shown, and the yield of the BODIPY fluorescent dye can be remarkably increased.

The present invention provides a kind of spherical gold powder and preparation method thereof, relate to the technical field of precious metal powder preparation, the preparation method uses aqua regia to prepare chloroauric acid solution, and uses concentrated hydrochloric acid to adjust pH to 1.5-2, then adds ammonia water to adjust pH to 7-9, stirs 20-60s, then adds concentrated hydrochloric acid to adjust pH to 1.2-2 again, obtains mixed solution B;Then, the first dispersant solution is poured into the aforementioned mixed solution B, after stirring evenly, the mixed solution A of the second dispersant and the reducing agent is quickly added, after stirring reaction, sedimentation, post-treatment, obtains spherical gold powder. Wherein, spherical gold powder of different sizes with a particle size within the range of 0.3-4 μm can be prepared by adjusting pH twice, and adding two different dispersants in a specific order of addition can make the prepared spherical gold powder uniform in particle size, good in dispersibility, regular in shape and smooth in surface. The preparation method reacts rapidly, the process is short and stable, and it has been stably expanded to 500g, which can realize large-scale industrial production.

The invention relates to the technical field of precious metal recovery, in particular to a process for separating precious metal from copper-nickel smelting waste, which comprises the following steps: crushing and grading the waste, adding a sulfuric acid solution containing etidronic acid, leaching, and washing, drying and crushing filter residues to obtain a pretreated material; mixing the pretreated material with a sodium peroxide-sodium carbonate composite flux, roasting, leaching with water, and filtering to obtain a filter residue B; adding a leaching agent containing hydrochloric acid, sodium chlorate and 1, 2-cyclohexanediamine tetraacetic acid into the filter residue B according to the ratio of 1: 3-1: 5, and filtering to obtain filtrate C and filter residue C; adjusting the pH value of the filtrate C to 1.5-2.5, adding an ethanol solution of sodium N, N-diethyldithiocarbamate, precipitating, washing and calcining to obtain sponge palladium; adding ammonium chloride into the filtrate D, precipitating and calcining to obtain sponge platinum; and leaching the filter residue C by using a hydrochloric acid-chloroauric acid mixed solution containing diphenylthiourea, and replacing and calcining zinc powder to obtain crude gold. According to the process, the leaching rates of platinum, palladium and gold and the product purity are greatly improved; flux and reagent systems are optimized, consumption and energy consumption are reduced, waste liquid treatment is matched for up-to-standard discharge, and efficient resource recovery and environment-friendly cooperation are achieved.

The invention belongs to the technical field of precious metal electronic paste, and particularly relates to a preparation method and application of submicron spherical gold-platinum-palladium alloy powder used for being matched with low-temperature co-fired ceramics. The preparation method comprises the following steps: mixing a tetrachloroauric acid solution, a hexachloroplatinic acid solution and a tetrachloropalladium (II) acid solution to obtain a gold-platinum-palladium mixed solution; the gold-platinum-palladium mixed solution, the dispersing agent solution and the modified reducing agent solution are mixed for a second time, after a reduction reaction is conducted, static settlement and solid-liquid separation are conducted in sequence, obtained solids are washed and dried in sequence, and the obtained submicron spherical gold-platinum-palladium alloy powder used for being matched with the low-temperature co-fired ceramic has the advantages of being uniform in particle size, free of agglomeration, high in dispersity and the like. After low-temperature co-firing with a ceramic substrate, the substrate has the characteristics of flatness, no bubble, excellent weldability and soldering resistance, good batch stability and the like.

The invention provides a GelMA microneedle patch loaded with chromogenic gold nano bipyramids and a preparation method thereof.The method comprises the steps that citric acid, chloroauric acid and a CTAC solution are mixed, then sodium borohydride is added, and a seed solution is obtained through stirring and standing; mixing chloroauric acid, silver nitrate, hydrochloric acid and CTAB (cetyltrimethyl ammonium bromide), and sequentially adding ascorbic acid and the seed solution to obtain a growth solution; carrying out centrifugation, morphology regulation and chemical etching purification to obtain a chromogenic gold nano bipyramid solution; the preparation method comprises the following steps: reacting gelatin with methacrylic anhydride in PBS, dialyzing and freeze-drying to obtain GelMA; dissolving GelMA in the gold nanoparticle bipyramid solution, and adding a photoinitiator LAP to obtain a mixed precursor solution; and the GelMA microneedle patch loaded with the gold nano bipyramid is prepared through mold casting, centrifugation, ultraviolet light crosslinking and drying demolding. The microneedle extraction and gold nano bipyramid color development integrated scheme is initiated, blood sampling is not needed, the dermis interstitial fluid is extracted in a minimally invasive mode through the microneedle, detection pain and trauma are reduced, the cross infection risk of blood treatment is avoided, and the microneedle microneedle microneedle microneedle microneedle microneedle microneedle microneedle microneedle microneedle microneedle microneedle microneedle microneedle microneedle microneedle microneedle microneedle microneedle microneedle microneedle microneedle microneedle microneedle

The invention belongs to the technical field of electro-catalysis, and particularly relates to a one-pot preparation method of a high-alloying gold-silver alloy aerogel material and application of the high-alloying gold-silver alloy aerogel material in electro-catalytic reduction of CO2. According to the preparation method, chloroauric acid and silver nitrate are selected as precursors for synthesizing the AuAg alloy aerogel, the AuAg alloy aerogel is prepared through a simple one-pot preparation method, and complex processes such as ultrafiltration centrifugal purification and concentration and heat treatment are not needed. Compared with an existing two-step method, the preparation process is complex, time and labor are consumed, and heat treatment is needed. However, according to the one-pot preparation method used in the invention, the high-alloying AuAg alloy aerogel can be obtained only by simply feeding, stirring and standing at room temperature. Moreover, the alloying degree of the obtained AuAg aerogel is higher, higher CO selectivity is shown in CO2RR application, and compared with AuAg alloy aerogel obtained through an existing two-step method, the CO Faraday efficiency of the AuAg aerogel is improved by about 37.1%.

The invention provides a preparation method of an organ-shaped MXene and one-dimensional WO3 nanorod nano self-reduction growth Au nanoparticle NO2 gas-sensitive composite material. The preparation method comprises the following specific steps: (1) preparing a high-molecular flexible substrate; (2) preparation of organ-shaped MXene; (3) preparing an MXene / WO3 composite material; and (4) preparation of an MXene / WO3 / Au composite material: the adding mass of accordion-shaped MXene is 5-160 mg, the adding amount of tetrachloroauric acid (HAuCl4. 3H2O) is 30 [mu] L, the product obtained by reaction is the MXene / WO3 / Au composite material, and the flexible substrate on which the composite gas sensitive material is deposited is the prepared NO2 sensor. The organ-shaped MXene and one-dimensional WO3 nanorod self-reduction growth Au nanoparticle NO2 gas-sensitive composite material prepared by the invention has a uniformly dispersed composite structure, the introduction of the organ-shaped MXene effectively improves the conductivity of WO3, and meanwhile, rich functional groups on the surface of the composite material contribute to improving the gas-sensitive property of WO3. Different electrodes can be deposited on the flexible substrate, the cost is low, the steps are simple and controllable, the flexibility is good, the sensitivity is high, and NO2 detection can be realized at room temperature.

The invention provides high-permeability colorimetric hydrogel for detecting the content of glucose in sweat and a preparation method of the high-permeability colorimetric hydrogel, and relates to the technical field of wearable colorimetric sensing. The preparation method of the high-permeability colorimetric hydrogel comprises the following steps: mixing polyoxyethylene polyoxypropylene ether, chloroplatinic acid, chloroauric acid and water, and then adding L-ascorbic acid for reaction to obtain gold-platinum nanocrystalline dendrites; the preparation method comprises the following steps: mixing polyvinyl alcohol, 3, 3 ', 5, 5'-tetramethyl benzidine, gold-platinum nanocrystalline dendrites, ethylene glycol and water to obtain a hydrogel precursor solution, and curing the hydrogel precursor solution to obtain a hydrogel precursor; and soaking the hydrogel precursor in a sodium chloride solution to obtain the high-permeability colorimetric hydrogel for detecting the content of glucose in sweat. The gold-platinum nanocrystal dendrite nanoenzyme has tandem bio-enzyme activity, glucose oxidase activity and peroxidase double-enzyme activity, and TMB is used as a chromogenic substrate to prepare the hydrogel, so that colorimetric detection of glucose can be realized.

The invention discloses a preparation method of nanorods, micro-nano particles and flaky mixed gold powder. The preparation method comprises the following steps: (1) taking ethylene glycol, high-purity water or a mixed solution of ethylene glycol and high-purity water as a solution a; (2) dissolving chloroauric acid in the solution a to obtain a solution b; (3) dissolving disodium ethylene diamine tetraacetate in the solution b to obtain a solution c; (4) dissolving polyvinylpyrrolidone in the solution c to obtain a solution d; (5) dissolving a reducing agent in the solution d to obtain a solution e; (6) adding sodium hydroxide into the solution e to obtain a solution f; (7) transferring the solution f into a polytetrafluoroethylene liner, and then performing hydrothermal reaction to prepare gold powder; and (8) washing, separating and drying the gold powder to prepare the gold powder with different shapes and sizes. The preparation method is simple, high-cost equipment is not needed, the batch morphology of the product is stable, and large-scale low-cost preparation of the gold powder is facilitated.

The invention belongs to the technical field of metal-organic framework functional materials, and particularly relates to a nickel-based metal-organic framework material, a plasmon nickel-based metal-organic framework composite material and a synthesis method and application of the nickel-based metal-organic framework material and the plasmon nickel-based metal-organic framework composite material. According to the invention, chloroauric acid is directly reduced into gold nanoparticles by using the reducibility of the nickel-based metal organic framework material, and the gold nanoparticles are loaded on the nickel-based metal organic framework material, so that uniform dispersion and firm loading of the gold nanoparticles on the nickel-based metal organic framework material are realized. The method has the advantages of simple synthesis method, convenience in operation and no need of additional reducing agent, is easy for large-scale preparation, and has better market application value and development prospect. The prepared plasmon nickel-based metal organic framework composite material is used as a photoelectrocatalytic reaction catalyst to be applied to photoelectrocatalytic reduction of nitrate to prepare ammonia, and the catalytic performance is excellent.

The invention discloses a device for preparing chloroauric acid through an electrolytic method, and particularly relates to the technical field of chloroauric acid preparation. The electrolytic preparation device for the chloroauric acid comprises a preparation pool, liquid discharge pipes are arranged on the two sides of the lower portion of the front end of the preparation pool, a central partition plate is arranged in the middle of the interior of the preparation pool, a flange plate frame is arranged in the central partition plate, and an anion exchange membrane is arranged in the flange plate frame; a reference electrode is arranged on one side of the anion exchange membrane, an anode plate is arranged on one side of the reference electrode, a cathode plate is arranged on the other side of the anion exchange membrane, connecting frames are arranged above the anode plate and the cathode plate, and a passivation cleaning mechanism is further arranged above the anode plate. And through the passivation cleaning mechanism, the problems that when the voltage in the groove of an existing preparation device rises to 1.30 V, the surface of an Au positive electrode is passivated, the positive electrode needs to be taken out to be washed or inhibited, and the electrolytic preparation efficiency is affected are solved.

The invention discloses a preparation method of a full-spectrum response plasmon photocatalyst for reducing carbon dioxide to prepare methane, and belongs to the technical field of photocatalytic reduction of CO2. Tungsten hexacarbonyl and silver nitrate, nickel chloride or chloroauric acid are used as raw materials, and a solvothermal reaction is performed to obtain a plasmon W18O49 nanowire photocatalyst doped with different metal ions. According to the preparation method for preparing the CH4 plasmon photocatalyst through full-spectrum response CO2 reduction, the prepared Au, Ag or N metal ion doped plasmon W18O49 nanowires have high ultraviolet-visible-near infrared light absorption capacity and rich surface oxygen vacancy concentration, adsorption and activation of CO2 molecules are facilitated, meanwhile, the surface oxygen vacancy concentration is increased, and meanwhile, the surface oxygen vacancy concentration is increased. The surface of the catalyst can effectively stabilize a * CO intermediate generated in the photocatalytic CO2 reduction process, and the performance and selectivity of the original plasmon W18O49 for preparing CH4 through photocatalytic CO2 reduction are remarkably improved.

The invention discloses a method for recovering valuable metals from copper anode slime step by step, and belongs to the technical field of metallurgy and chemical industry. According to the method, through control over the oxidation-reduction potential, the oxidation-reduction potential is high in the leaching stage, and it is guaranteed that gold, selenium, tellurium and the like can be oxidized to enter a leaching solution; in the reduction stage, gold, selenium and tellurium products are reduced step by step according to the difference of gold, selenium and tellurium in reduction potentials; in the leaching stage, soluble chlorine salt is added while enough oxidation potential is guaranteed, enough chloride ions are provided for the solution, and therefore gold can enter the solution in the form of AuCl4-(tetrachloroauric acid); meanwhile, in the oxidation leaching stage, a small amount of silver enters the solution in the form of silver sulfate or silver complex, and under the condition that enough chloride ions are provided, silver is precipitated and retained in residues in the form of silver chloride, so that separation of gold and silver is achieved, and meanwhile dispersion of gold and silver in the leaching process is reduced. According to the method, valuable metal is efficiently separated and recycled.

The invention discloses a gold-silver alloy nanoprobe based on double-signal cooperative detection, a preparation method and application thereof, and belongs to the technical field of sensing. Then mixing the gold nanorod, a Raman report molecule p-methylthiobenzonitrile and a chiral stimulating factor L-cysteine, and jointly incubating at room temperature to obtain a mixed solution; sequentially adding silver nitrate, chloroauric acid tetrahydrate and ascorbic acid into the mixed solution, and magnetically stirring; and placing the mixed solution under a constant temperature condition to react for a certain time, so that the gold-silver alloy shell fully grows, and finally obtaining the spiral structure alloy nanoprobe with Raman signals and CD signals. The probe realizes the dual detection functions of Raman signals and circular dichroism signals, and can detect the lactic acid concentration with high sensitivity and high selectivity by combining the specific catalytic action of the lactate oxidase, and meanwhile, the Raman signals and CD signals of the silent zone can further expand the application range of the probe.

The invention belongs to the field of biosensor detection, and particularly discloses a colorimetric detection method based on functionalized copper cysteine nano-enzyme, which comprises the following steps: preparing a specific functionalized copper cysteine nano-enzyme composite material; and constructing a detection reaction system containing hydrogen peroxide, tetramethyl benzidine, an acetate buffer solution and a target solution, and determining the concentration of the target by using a colorimetric analysis technology. Particularly, CuCl2. 2H2O is used as a copper source, PEG-4000 is used as polyethylene glycol, reaction is performed under nitrogen protection and alkalescence conditions, and then the reaction product reacts with chloroauric acid and trisodium citrate to prepare the composite material. According to the method, hydrogen peroxide and tetramethyl benzidine are taken as substrates, high-sensitivity detection of a target object (such as dopamine) is realized by measuring an absorption peak value of a reaction system at 652nm, and a standard curve is drawn so as to accurately measure the concentration of a solution to be measured. The method is simple and convenient to operate and high in sensitivity, and has a wide application prospect in detection of biological molecules such as dopamine.

The invention provides a water-phase preparation method of sodium citrate-mediated size-controllable gold layer-coated ferroferric oxide nanoparticles. The water-phase preparation method comprises the following steps: step 10, preparing a sodium citrate-modified ferroferric oxide nanoparticle solution; and step 20, adding a sodium citrate solution, a chloroauric acid solution and a hydroxylamine hydrochloride solution into the sodium citrate modified ferroferric oxide nano-particle solution to prepare the gold layer coated ferroferric oxide nano-particles. According to the water-phase preparation method of the sodium citrate-mediated size-controllable gold layer-coated ferroferric oxide nano-particles, provided by the invention, the preparation of the gold layer-coated ferroferric oxide nano-particles with controllable size, adjustable magnetic nucleus size, no intermediate layer and low cost can be realized.

The invention relates to a preparation method and application of an AuPd alloy nanoparticle doped ZnO sensing material, and belongs to the field of gas sensing. According to the invention, sodium hydroxide is used as a solution to provide an alkaline environment, zinc nitrate hexahydrate is used as a zinc source, chloroauric acid and palladium chloride are used as a gold source and a palladium source, deionized water is used as a solvent, and the AuPd-ZnO gas-sensitive sensing material is prepared through the steps of mechanical stirring, microwave-assisted hydrothermal method synthesis, centrifugation, drying and the like. The sensor based on the AuPd-doped ZnO nano material has good gas-sensitive performance on acetone, and has high response, ideal stability and good selectivity. The response to 50 ppm ethanol is 32, the lower limit of detection is 5 ppm, and high stability is shown in a continuous peripheral gas-sensitive test. The method is simple in preparation process, low in equipment requirement and high in controllable degree, and the obtained product is uniform, has excellent gas-sensitive performance, can realize trace detection of ethanol and can be used as an ideal sensing device for ethanol detection.

The invention provides a preparation method of a nano-gold star material, which comprises the following steps: stirring and heating a chloroauric acid solution, adding a sodium citrate solution, continuously stirring and heating, when the color of the solution is changed from colorless to dark red, adjusting the rotating speed to 600rpm, turning off a heating device, cooling at room temperature, filtering the reacted solution by using a water-based filter membrane, and drying to obtain the nano-gold star material. Removing impurities to obtain a gold seed solution; characterizing the gold seed solution and the gold seed particles; the preparation method comprises the following steps: adding a 4-hydroxyethyl piperazine ethanesulfonic acid solution, a gold seed solution, a hydroxylamine solution and a magnetic rotor into deionized water, dropwise adding a 22.5 mM chloroauric acid solution, adjusting the rotating speed to 700rpm, and reacting for 15 minutes at room temperature to obtain the nano gold star material. The prepared nano gold star material is uniform, stable, adjustable in particle size and high in dispersity, the material is in a three-dimensional multi-branch shape, and the diameter of the material is adjustable within 50-200 nm.

The invention discloses a microbial fermentation real-time monitoring and molecular analysis method based on a single-cell Raman spectrum technology. The method comprises the following steps: firstly, preparing basic gold nanospheres which are microcosmically spherical and have the particle size distribution of 20-40 nm through a chloroauric acid oxidation reduction method, and characterizing the morphology of the basic gold nanospheres; secondly, the surface of the basic gold nanosphere is coated with a silicon dioxide thin layer through tetraethoxysilane hydrolysis and polymerization reaction, and the silicon dioxide functionalized gold nanosphere with the core-shell structure is prepared to serve as the microorganism living cell probe. The probe and different microbial cells are co-cultured, Raman fingerprint spectrums of the cells are sensitively captured, the single-cell Raman fingerprint spectrums are deeply analyzed by adopting a machine learning technology, and differential analysis (including strain difference, environment difference, metabolic capability difference and the like) is combined to determine the single-cell Raman fingerprint spectrums of the cells. Molecular indexes of specific expression of the microbial cells in different industrial production processes and different culture periods are screened out. The invention provides a universal tool for accurately realizing real-time monitoring and molecular analysis of microbial cells in different industrial processes, and has a wide industrial application prospect.

The invention belongs to the field of catalytic materials, and particularly discloses a double noble metal supported molecular sieve catalyst for catalyzing oxygen to oxidize methane to prepare acetic acid. The preparation method comprises the following steps: mixing a chloroauric acid solution and another noble metal chloride solution as precursors with a molecular sieve, adjusting a certain pH value, stirring and aging at a proper water bath temperature for a certain time, and then filtering, drying and calcining to obtain the catalyst. According to the catalyst, a molecular sieve is used as a carrier, gold is used as an oxidation active center, carbon-carbon coupling is achieved with another precious metal, high-selectivity acetic acid preparation through methane pure oxygen direct oxidation can be achieved under the mild condition of 120-240 DEG C, and the selectivity reaches up to 97.2%. The catalyst preparation method adopted by the invention is simple in process, green and pollution-free, high in noble metal loading efficiency, low in price and easy for expanded production, and provides a thought for developing and preparing a high-efficiency catalyst for direct selective oxidation of methane under mild conditions.

The present invention belongs to but is not limited to the field of medical detection technology, and particularly relates to a system, method and equipment for detecting information of a target in a cell, including: a glass capillary pretreatment module: the nano glass tube used is a borosilicate glass tube with a specification of BF100-58-10, and a capillary puller P-2000 is used to pull a nano pipette with a size of about 200 nanometers; a gold particle nanolayer is modified inside the tip of the nano pipette by a chloroauric acid reduction method; a detection probe design unit module: a controllable light-activated functional DNA probe containing a thiol bond is used to modify the functionalized DNA on the surface of the gold layer inside the nano pipette through the action of a gold-sulfur bond. Based on the probe design unit module, the detection system will feedback different information according to the detected object, thereby realizing the specific detection of the target in the cell; the detection unit module: electrochemical signal detection, fluorescence signal detection and dual signal collection are performed.

The invention discloses an Au7Cu10 nanocluster and a preparation method and application thereof.The preparation method comprises the following steps that chloroauric acid and cuprous chloride serve as a gold source and a copper source respectively and are dissolved and stirred in a solvent, 1-adamantanethiol is added, and the color of the solution is changed into dark green from yellow; continuously adding diphenyl-2-pyridine phosphine to enable the color of the solution to be changed from dark green to light orange, continuously adding a mixed solution of sodium borohydride and ice water, and isolating air to enable the color of the solution to be quickly changed into black; and centrifuging to remove a water phase, evaporating an organic phase, washing black precipitate, recrystallizing a crude product at low temperature, and culturing to obtain the Au7Cu10 nanocluster. The Au7Cu10 nanocluster disclosed by the invention shows excellent performance, so that the Au7Cu10 nanocluster has the potential of serving as molecular triplet energy and an electronic substitute in optoelectronics, photocatalysis and solar energy conversion.

The invention discloses a nano-enzyme detection method for aflatoxin B1, and relates to the technical field of analysis and detection.The method comprises the following specific steps that nano-enzyme preparation and carrier selection are conducted, specifically, nano-gold is prepared through a sodium citrate reduction method to serve as the nano-enzyme, a chloroauric acid solution is added into a round-bottom flask and heated to be boiled, and a carrier is obtained; according to the method, the PNIPAM serves as an immobilization carrier of the nano-enzyme, reversible immobilization of the nano-enzyme is achieved, cyclic utilization of the nano-enzyme is promoted, the detection cost is reduced, after detection is completed, phase change of the PNIPAM can be achieved by changing environmental conditions, and therefore effective separation of nano-gold and the carrier is achieved; after the recovered nanogold is washed and subjected to re-functionalization treatment, the catalytic activity of the nanogold is maintained, and the nanogold can be used for detecting aflatoxin B1 again, so that the utilization rate of the nano-enzyme is increased, and the waste of resources is reduced.

The invention discloses a visible light photocatalyst for in-situ synthesis of hydrogen peroxide and a preparation method and application thereof, belonging to the technical field of photocatalytic material preparation; the invention adopts a wet impregnation method to impregnate a covalent organic polymer with chloroauric acid so that the chloroauric acid is evenly distributed on the inner surface of the covalent organic polymer, thereby assisting sodium borohydride reduction to obtain gold nanoparticles and loading them on the covalent organic polymer to synthesize a gold-loaded covalent organic polymer (Au / COFs) visible light photocatalyst; the photocatalyst can significantly improve the absorption capacity of visible light, has good visible light photoresponse and excellent photocatalytic performance, and can efficiently reduce oxygen to synthesize hydrogen peroxide in situ under visible light; the photocatalyst can be applied to the environmental field of sustainable development and the field of clean production, sterilizes water bodies by combining with advanced oxidation technology, and the preparation method is simple, the synthesis efficiency is high, meets the actual production needs, and has high practical value and good environmental significance.

The application provides a preparation method of a SERS substrate of a zirconium-based MOF-808 / AuNPs. The method comprises three steps: in the first step, an AuNPs solution is prepared by using deionized water, chloroauric acid and sodium citrate to perform an oil bath reaction to obtain the AuNPs solution; in the second step, MOF-808 is prepared by mixing zirconium chlorohydrate, 1,3,5-benzene tricarboxylic acid, N,N-dimethylformamide and formic acid, and then performing a hydrothermal reaction on the mixed solution, centrifuging and vacuum drying to obtain activated MOF-808-Zr powder; in the third step, the activated MOF-808-Zr powder is dissolved in anhydrous ethanol, and then fully stirred and mixed with AuNPs solutions of different amounts to form a zirconium-based MOF-808 / AuNPs solution; and in the fourth step, the zirconium-based MOF-808 / AuNPs solution is poured into sample boxes containing silicon substrates, and the silicon substrates are immersed, and after drying, a SERS substrate of the zirconium-based MOF-808 / AuNPs is obtained. The method has the advantages of simple preparation process, low cost, good uniformity of the prepared substrate, good signal repeatability, high sensitivity, good structural stability and the like.

The invention relates to a nanogold aggregate capable of realizing kidney excretion, a preparation method and application of the nanogold aggregate as a CT contrast agent, and the preparation method comprises the following steps: mixing a chloroauric acid solution, an alkali solution and a sulfydryl hydrophilic compound to obtain a mixed solution A; under the ice-water bath and stirring conditions, a reducing agent is added into the mixed solution A, and a mixed solution B containing nano-gold particles is obtained; mixing the mixed solution B with a wrapping material-buffer solution to obtain a mixed solution C containing the gold nanoparticles and the wrapping material; adding a positively charged compound solution into the mixed solution C to obtain a mixed solution D; the nanogold becomes a stable aggregate through a positively charged compound; and centrifuging the mixed solution D to obtain the nanogold aggregate capable of realizing kidney excretion. The synthesized ultra-small nanogold is agglomerated into the nanogold aggregate with a stable structure, the contrast agent can be obtained through simple centrifugal concentration, the contrast agent is stable in property and good in biocompatibility, and the contrast agent can be discharged out of a body along with urine within a period of time after entering the body.

The application belongs to the technical field of fluorescent probe detection, and discloses a bimetallic nanocluster fluorescent probe compound and application thereof in preparation of a product for rapidly detecting acetylene. The fluorescent probe compound is a gold-copper bimetallic nanocluster solution modified by adamantane thiol, which is used as a fluorescent probe for acetylene detection. The solution has a clear and controllable preparation process. Through specific proportioning and reaction conditions of cuprous chloride, adamantane thiol, tetrachloroauric acid, sodium borohydride and other reagents, a probe solution with stable fluorescence characteristics can be prepared. The bimetallic nanocluster fluorescent probe compound is applied in preparation of a product for rapidly detecting acetylene. Through specific combination of fluorescent molecules and acetylene gas to trigger the secondary effect of fluorescence quenching, detection is realized, and other substances cannot trigger quenching. At a wavelength of 700 nm, the linear relationship (R 2 >0.99) between the fluorescence intensity and the acetylene concentration realizes accurate quantification of the acetylene concentration, and the minimum detection limit is 0.026 muL / L.

The invention provides a preparation method of high-sphericity gold powder, and relates to the technical field of nano material preparation. The preparation method comprises the following steps: sequentially adding a multi-ligand stabilizer solution and an acid solution into a chloroauric acid solution, and adjusting the pH value of a reaction system to 4.0-5.0 to obtain a solution A; then, quickly adding a dispersing agent solution into the solution A for first-stage mixing, and then, quickly adding a reducing agent solution for second-stage mixing; and then, a morphology optimizing agent solution is dropwise added into a reaction system, precipitates are collected after full reaction, and the high-sphericity-degree gold powder is obtained. According to the method, a multi-ligand stabilizer is added into a chloroauric acid solution, and accurate control over the morphology of the gold powder is achieved through competitive adsorption between ligands. On the basis, an acid solution is added into a chloroauric acid solution, morphology control over the gold powder is further consolidated, the pH value of the solution adjusted through the acid solution is acidic, the reduction rate is further decreased, and the gold powder is better in dispersity and more uniform in size.

The utility model discloses a chloroauric acid crystallization device which comprises a crystallization kettle and a driving motor, the bottom of a stirring piece is rotatably connected with the inner wall of the crystallization kettle through a rotating shaft, scrapers are fixedly connected to the two sides of the curved surface of a transmission column, and a water inlet device is arranged at the bottom of the driving motor. A cleaning device used in cooperation with the water inlet device is arranged at the top of the inner cavity of the crystallization kettle, a transmission assembly used in cooperation with the cleaning device is arranged at the top of the scraper, and a transmission gear ring used in cooperation with the transmission assembly is arranged at the top of the curved-surface inner wall of the crystallization kettle. According to the crystallization kettle, the water inlet device, the cleaning device and the transmission assembly are matched for use, so that the problems that after an existing crystallization kettle is used, residues usually appear on the inner wall of the crystallization kettle, the residues on the inner wall generally need to be manually removed, the process is time-consuming and high in labor intensity, and the use of the crystallization kettle is influenced are solved.

The invention belongs to the technical field of pyruvic acid biological detection, and relates to a pyruvic acid sensing chip of a Prussian blue nano frame / gold nano composite material. The method comprises the following steps: adding soluble metal salt containing ferricyanide ions into water; the method comprises the following steps: adding soluble ferric salt and a complexing agent into water, mixing, and carrying out hydrothermal synthesis reaction to obtain PB powder; adding PB powder into ethanol, adding ammonia water for reaction, mixing with conductive carbon paste to obtain nano printing paste, and printing the printing paste on a substrate to form a working electrode; the preparation method comprises the following steps: preparing a working electrode, drying the working electrode, placing the working electrode in a chloroauric acid solution for constant potential electrodeposition, mixing a PBS solution of pyruvate oxidase, a polylysine solution and an EDC solution, dropwise adding the mixture on the surface of the working electrode, and drying to obtain the pyruvic acid sensing chip. The obtained pyruvic acid sensor can reach the sensitivity of 50.42 [mu] A.mM <-1 >. Cm <-2 >, and is simple in preparation process and relatively low in cost.