1053 results about "Nitrobenzene" patented technology

The invention discloses a preparation method of second-generation denitrified flavin TND1128, which comprises the following steps: S1, by taking 1-methylbarbituric acid and o-aminobenzaldehyde as raw materials and a mixture of water and alcohol as a solvent, heating and reacting to generate an intermediate I; s2, taking the intermediate I as a raw material, and performing ethylation under the combined action of inorganic alkali and an ethylation reagent to generate a TND1128 crude product; s3, the TND1128 crude product is purified, and a TND1128 pure product is obtained; according to the invention, 1-methylbarbituric acid and 2-nitrobenzaldehyde are taken as raw materials for cyclization synthesis of an intermediate I, then ethylation and pulping purification are carried out under the combined action of inorganic base and an ethylation reagent, and high-purity TND1128 is synthesized in a high-yield, high-specificity and high-selectivity manner; the method has the advantages of simple process route, good reaction selectivity, high yield, cheap and easily available raw materials, low equipment requirement, easy realization of industrial production and the like.

The invention discloses a method for joint production of cyclohexylamine and dicyclohexylamine, which comprises the following steps: 1) feeding aniline tail gas of a nitrobenzene catalytic hydrogenation production device into a gas-liquid separator for gas-liquid separation to obtain aniline tail hydrogen and aniline condensate; 2) mixing aniline tail hydrogen and new hydrogen as a raw material A, and mixing defective aniline and fresh aniline in proportion as a raw material B; (3) feeding the vaporized raw material B and the vaporized raw material A into a fixed bed reactor according to a certain hydrogen-oil ratio, and carrying out hydrogenation reaction; a hydrogenation reaction product is subjected to heat exchange condensation and then enters a gas-liquid separator for gas-liquid separation, a gas phase serves as recycle hydrogen to be mixed with the raw material A, and a liquid phase is fed into a distillation device; and 4) carrying out primary distillation and rectification purification in sequence to obtain cyclohexylamine and dicyclohexylamine. According to the method, aniline tail gas resources and defective aniline are fully utilized, the three-waste treatment cost is reduced, product benefits can be improved, pollution to the environment can be reduced, and economic benefits and social benefits are remarkable.

The invention relates to a method for degrading nitrobenzene pollutants by using a humus-synergistic enhanced Fenton system, which comprises the following steps: adding a peroxide oxidant, a Fe (III) catalyst and a water-soluble organic reducing agent with Fe (III) reducing capacity into soil containing nitrobenzene pollutants, uniformly mixing to form a Fenton system, adding humus, and uniformly mixing to form the nitrobenzene pollutants. Mixing and reacting to obtain the soil for degrading the nitrobenzene pollutants. Compared with the existing Fenton technology, the method has the advantages that the overall catalytic efficiency can be improved, the initial pH does not need to be adjusted, and the method is green, safe and environmentally friendly.

The invention discloses a crystallization process of o-chloro-p-nitroaniline, which comprises the following steps: feeding a material into a crystallization kettle to crystallize the o-chloro-p-nitroaniline, regulating and controlling the temperature in the kettle body in the crystallization process, cooling to a metastable region of the o-chloro-p-nitroaniline, preserving the heat in the metastable region for a first preset time length, and then cooling to a second preset time length; continuously cooling to a first temperature lower than the melting point of the o-chloro-p-nitroaniline, keeping the temperature at the first temperature for a second preset duration, continuously cooling to a second temperature, and outputting the material out of the crystallization kettle for filtration and separation; in the cooling process, the cooling speed in the kettle body is controlled to be 0.1-0.2 DEG C / min. According to the invention, the interior of the kettle body can be slowly cooled, and the cooling speed of each part in the kettle body can be more uniform, so that the crystallization purity and the product quality of o-chloro-p-nitroaniline are finally improved.

The invention discloses a metal supported activated carbon catalyst for efficiently preparing aquacide dichloride and application of the metal supported activated carbon catalyst. The catalyst is prepared by taking activated carbon as a carrier, loading Lewis acid active components such as aluminum ions, zinc ions, iron ions, copper ions and the like through an impregnation method, and carrying out vacuum pyrolysis activation treatment at 300-600 DEG C. The catalyst synergistically catalyzes a nucleophilic substitution reaction of a pyridine derivative and alkyl halide in an aprotic polar solvent such as acetonitrile or nitrobenzene, and synthesis of diquat dichloride can be realized under the conditions that the temperature is 100-180 DEG C and the pressure is 1-3 MPa. In a reaction system, the mass ratio of the pyridine derivative to the catalyst to the solvent is 1: (0.01-0.05): (5-8), and real-time monitoring and regulation are performed through an online infrared spectrum, a liquid chromatograph and a gas chromatograph-mass spectrometer. The purity of the product is more than 99% after the product is subjected to filtration, recrystallization with an ethanol-water mixed solvent and vacuum drying. The catalyst provided by the invention has the characteristics of high activity, strong stability and recoverability, obviously improves the atom economy of the reaction, simplifies the production process, reduces the energy consumption and pollution, and is suitable for large-scale industrial production.

The invention discloses an aggregation-induced emission metal organic framework, a preparation method thereof and application of the aggregation-induced emission metal organic framework in portable detection of low-concentration nitrobenzene. According to the aggregation-induced emission metal organic framework, ZrCl4 provides Zr < 4 + >, 2-sulfonic terephthalic acid and AIE molecule 2, 3, 5, 6-tetra (4-carboxyl phenyl) pyrazine as organic ligands, an aggregation-induced emission fluorescent material is obtained through a solvothermal method, due to the coordination effect and limited intramolecular rotation, the material shows bright blue fluorescence, and the fluorescence intensity of the aggregation-induced emission metal organic framework is greatly improved. The aggregation-state fluorescence can be obviously quenched after the fluorescent probe is contacted with nitrobenzene. The aggregation-induced emission metal organic framework material is obtained by utilizing the aggregation-induced emission performance of aggregation-induced emission molecules, and the material has good detection capability on nitrobenzene, can rapidly and efficiently detect nitrobenzene in a solution, and has good cycle performance. Meanwhile, the nitrobenzene gas can be detected for multiple times, and good sensitivity and practicability are achieved.

The invention discloses a selective etching solution for a titanium and / or copper metal layer of a circuit board and a preparation method of the selective etching solution, and the selective etching solution comprises the following components: 10-20% of persulfate, 4-8% of o-nitrobenzenesulfonate, 0.5-1% of phosphoric acid, 0.2-0.8% of 3-(aminomethyl) pyrazole, 0.3-1.5% of ammonium fluoride, 2-5% of cyclohexanediamine tetraacetic acid, 0.1-0.5% of cyclodextrine and the balance of water. The etching solution can selectively etch a titanium and / or copper metal layer, through selection and cooperation of etching solution components, etching is uniform and stable, taper angle and lateral etching control is good, metal wires are smooth, no metal residues exist, and a good etching solution is provided for the circuit board etching process.

The present invention relates to a fluxapyroxad intermediate trifluoronitrobiphenyl synthesis method, and belongs to the technical field of organic synthesis, the method comprises the following steps: Step 1: under nitrogen protection, adding 3, 4, 5-bromotrifluorobenzene, o-nitrophenylboronic acid, a catalyst, a promoter, an alkali and a solvent into a reaction flask, and after addition, carrying out a heat preservation reaction; and Step 2: after the reaction is finished, carrying out phase splitting and organic phase concentration to obtain the 3 ', 4', 5 '-trifluoro-2-nitrobiphenyl. Compared with a traditional synthetic method of the trifluoro-nitrobiphenyl, the synthetic method of the trifluoro-nitrobiphenyl has the advantages that the 3, 4, 5-trifluoro-bromobenzene and the o-nitrophenylboronic acid are directly used as raw materials, the production step of preparing the 3, 4, 5-trifluoro-phenylboronic acid from the 3, 4, 5-trifluoro-bromobenzene through a multi-step reaction is avoided, the yield can be effectively improved, the utilization rate of the raw materials is high, and the method is suitable for industrial production. And the o-nitrophenylboronic acid preparation method is simple, the reaction cost can be effectively reduced, the reaction route is shorter, simpler and more efficient, the reaction conditions are mild, and the method has higher industrial application value.

The invention discloses a phase transfer catalyst of metal ion complexing crown ether for efficiently preparing aquacide dichloride and application of the phase transfer catalyst. The catalyst is prepared by taking crown ethers as 18-crown-6 and dicyclohexyl-18-crown-6 ether and complex ions as lewis acid active components such as potassium ions, lithium ions, cobalt ions, copper ions and the like through a direct chemical method. The catalyst synergistically catalyzes a nucleophilic substitution reaction of a pyridine derivative and alkyl halide in an aprotic polar solvent such as acetonitrile or nitrobenzene, and synthesis of diquat dichloride can be realized under the conditions of 60-140 DEG C, normal pressure and no oxygen. The mass ratio of the pyridine derivative to the catalyst to the solvent in a reaction system is 1: (0.001-0.05): (5-8), and real-time monitoring and regulation are performed through an online infrared spectrum, a liquid chromatograph and a gas chromatograph-mass spectrometer. The purity of the product is more than 99% after the product is subjected to filtration, recrystallization with an ethanol-water mixed solvent and vacuum drying. The catalyst provided by the invention has the characteristics of high activity, strong stability and recoverability, obviously improves the atom economy of the reaction, simplifies the production process, reduces the energy consumption and pollution, and is suitable for large-scale industrial production.

The invention relates to the technical field of chloronitrobenzene hydrogenation catalysts, in particular to a chloronitrobenzene hydrogenation catalyst and a preparation method thereof.The method comprises the steps that 1, after an active metal source, a carbon source, a template agent and a solvent are mixed, the solvent is removed, and a solid is obtained; (2) roasting the solid obtained in the step (1) in an inert gas atmosphere to obtain a roasted product; and (3) contacting the roasted product with an acid solution, separating, washing and drying to obtain the hydrogenation catalyst. The active metal source is soluble salt of active metal, and the active metal is selected from one or more of Fe, Co, Ni, Cu and Zn; the template agent is selected from one or more of magnesium-containing compounds. According to the preparation method of the hydrogenation catalyst, the non-noble metal is selected, the pickling solution can be recycled, the catalyst is environment-friendly, the production and recovery cost is reduced, and the catalyst is excellent in performance and has no dechlorination phenomenon when being used for preparing chloroaniline through hydrogenation of chloronitrobenzene.

The invention discloses 1, 2-dibromo-6-tert-butyl-9-(4-tert-butylphenyl)-9H-carbazole and a synthesis method of the 1, 2-dibromo-6-tert-butyl-9-(4-tert-butylphenyl) The method comprises the following steps: taking 3-nitrophthalic acid as an initial raw material, reacting trichloroisocyanuric acid with liquid bromine to obtain 1, 2-dibromo-3-nitrobenzene, reducing by stannous chloride to obtain 2, 3-dibromoaniline, carrying out diazotization reaction to obtain 2, 3-dibromophenylhydrazine, reacting with p-tert-butyl cyclohexanone, and reacting by using 2, 3-dichloro-5, 6-dibromophenylhydrazine to obtain 2, 3-dibromophenylhydrazine. The preparation method comprises the following steps: carrying out dehydrogenation on 2, 6-dicyanobenzoquinone to obtain 1, 2-dibromo-6-tert-butyl-9H-carbazole, and finally reacting the 1, 2-dibromo-6-tert-butyl-9H-carbazole with 4-tert-butyl iodobenzene to obtain the 1, 2-dibromo-6-tert-butyl-9-(4-tert-butylphenyl)-9H-carbazole. Due to the existence of a bromine atom functional group on the 1, 2-dibromo-6-tert-butyl-9-(4-tert-butylphenyl)-9H-carbazole, the further conversion of the compound has expandability, and the compound can be used as a material / drug molecule precursor in the fields of organic light-emitting semiconductors, pharmaceutical chemistry and the like.

The invention discloses a method for reducing nitro compounds through an electrochemical microreactor. According to the method, nitrobenzene or a derivative thereof is subjected to electrochemical catalysis in a multi-channel series electrolytic tank in a constant-current electrolysis mode to be reduced to generate aniline or a corresponding aniline derivative. According to the method disclosed by the invention, the Faraday efficiency is improved from 40% to more than 80% under the condition that the yield of the nitrobenzene is kept unchanged compared with that of the existing electrochemical reduction nitrobenzene, so that the fixed energy consumption is greatly reduced, and rapid, efficient, continuous and large-scale production of the nitrobenzene and the derivatives thereof is realized.

The invention belongs to the field of electrochemistry, and discloses a self-growing solid electrolyte interface in an electrolysis process and application of the self-growing solid electrolyte interface in aniline production. The method comprises the following steps: dissolving nitrobenzene, 2-piperidone, lithium bromide and tris (N, N-tetramethylene) phosphamide in an organic solvent to obtain an electrolyte, and placing the electrolyte in a single-chamber electrolytic tank provided with an anode and a cathode for electrolysis, so that a solid electrolyte interface automatically grows on the cathode along with electrolysis and generates electrocatalytic activity. According to the method, hydrogen is not used, so that the risks of combustion and explosion are avoided; the device can be coupled with clean energy power generation, and is environment-friendly and sustainable; the device is simple, the size of the device is obviously reduced, and an exchange membrane does not need to be used for separating a cavity; a catalyst does not need to be loaded on an electrode, and the cost and technical difficulty of synthesizing and loading the catalyst are avoided; the price is low and operation is easy; the problems of inactivation and shedding of the catalyst do not need to be considered, and the long-term stability is good.

The invention belongs to the technical field of optical drive catalytic materials, and discloses a preparation method of a foamed ceramic-metal organic framework composite catalytic material and application of the foamed ceramic-metal organic framework composite catalytic material in photo-thermal catalytic elimination of nitro compounds. According to the invention, photo-thermal catalytic MOFs are loaded on foamed ceramic, and a floatable integrated photocatalytic material is formed through in-situ self-assembly and is used for solar-driven nitro-compound thermal elimination. MOFs have high specific surface area, high porosity, good light absorption and high photo-thermal conversion efficiency; the foamed ceramic has the characteristics of strong adsorbability, good heat conduction, light weight, adjustable size and the like. The combination of the two overcomes the problems of difficult recovery, more residues and low efficiency of the traditional powder catalyst and the high cost, high energy consumption, high-temperature danger and the like of the traditional photo-thermal catalysis, and shows huge application potential. The method can be used for treating organic wastewater containing toxic nitro compounds (such as trinitrotoluene, dinitrobenzene, nitrochlorobenzene and the like), and a new thought is provided for wastewater treatment in the fields of explosives, medicines, pesticides, dyes and the like.

The invention discloses a synthesis method of 2, 4, 5-trifluorophenylacetic acid, which comprises the following steps: by taking cheap and easily available o-chloronitrobenzene as a raw material, reacting with sodium nitrate in a sulfuric acid and trifluoroacetic acid system, separating generated 2, 4-dinitrochlorobenzene through melt crystallization, and continuing to synthesize 2, 4-dinitrochlorobenzene in methyl chloroacetate to obtain 2, 4, 5-trifluorophenylacetic acid. The method comprises the following steps: carrying out indirect aromatic nucleophilic substitution reaction on 2, 4-dinitrophenylacetic acid under the condition of sodium hydride to generate 5-chloro-2, 4-dinitrophenylacetic acid methyl ester, separating, carrying out fluorination reaction on the 5-chloro-2, 4-dinitrophenylacetic acid methyl ester and potassium fluoride under the action of a phase transfer catalyst, carrying out rectification separation to obtain 2, 4, 5-trifluorophenylacetic acid, and carrying out hydrolytic acidification on the 2, 4, 5-trifluorophenylacetic acid in a sodium hydroxide aqueous solution to obtain 2, 4, 5-trifluorophenylacetic acid. And the process route is safer, more environment-friendly, more efficient and lower in cost.

The invention discloses a high-flame-retardant bio-based aerogel material and a preparation method thereof, and belongs to the technical field of flame-retardant bio-based aerogel. The high-flame-retardant bio-based aerogel material prepared by the preparation method disclosed by the invention is prepared from the following raw material components in parts by mass: 10 parts of a bio-based flame-retardant filler with a porous structure, 40 to 50 parts of a hydrophobic siloxane monomer, 12.4 to 12.6 parts of an ammonium phytate solution, 6.2 to 6.3 parts of guanosine, 31.1 to 31.4 parts of cellulose nanofibers and 0.01 to 0.02 part of benzaldehyde-polyethylene glycol-silane, the preparation method comprises the following steps: firstly, carrying out hydrolytic polycondensation on a bio-based flame-retardant filler with a porous structure and a hydrophobic siloxane monomer to form a siloxane polymer network with the bio-based flame-retardant filler as a branching center; then adding cellulose nanofibers, guanosine and an ammonium phytate solution, and performing freeze casting-freeze drying-heating post-treatment to obtain the composite material. Wherein the bio-based flame-retardant filler is obtained by compounding a porous cuttlefish ink carbon quantum dot composite material with phytic acid siloxane and trimethoxy (3-(4-nitrophenoxy) propyl) silane.

The invention provides bisphenol A polyoxypropylene ether and a preparation method thereof. The bisphenol A polyoxypropylene ether is prepared from bisphenol A, epoxypropane and a modified chain extender, the modified chain extender is obtained by modifying pentaerythritol with a compound containing nitryl, phenyl, halogen atoms and silane; the chain extender is beneficial to improving the rebound resilience of a polyether system, and the branched structure increases the volume / mass ratio and is beneficial to light weight; according to the bisphenol A polyether, the NO2 group has a certain self-extinguishing property, and the combination of aryl, F and Si has a good synergistic flame-retardant effect, so that a positive contribution is made to the flame-retardant property, and especially in the aspects of forming a stable carbon layer and suppressing smoke, the sealing, rebounding, flame-retardant and lightweight properties of the bisphenol A polyether are synergistically improved.

The invention relates to a preparation method of a carbon-based gold-containing bimetallic catalyst. The specific method comprises the following steps: carrying out secondary doping on eigenstate polyaniline, carrying out high-temperature pyrolysis in an inert atmosphere to obtain a heteroatom-doped carbon-based carrier, and changing the variety, the content and the distribution of heteroatoms on the carbon surface of the carrier by adjusting the variety and the content of acid. And preparing gold-containing bimetallic nanoparticles by using a colloid method, and depositing bimetallic particles by virtue of adsorption of the carbon carrier and bimetallic to obtain the carbon-based gold-containing bimetallic catalyst. Wherein the doping element can anchor and disperse the noble metal, and the introduced second metal can improve the hydrogenation activity of the catalyst. The catalyst is simple in preparation process, good in activity, excellent in selectivity and excellent in cycling stability, is particularly suitable for a reaction for preparing 4-chloroaniline through catalytic hydrogenation of 4-chloronitrobenzene, and has good application potential.

The invention belongs to the technical field of preparation of nano noble metal catalysts, and relates to a preparation method of a doped carbon-based nano noble metal catalyst. Phytic acid doped polyaniline is prepared through chemical oxidative polymerization, a nitrogen and phosphorus co-doped carbon carrier is obtained through pyrolysis under the nitrogen atmosphere, gold and palladium bimetal is loaded through a metal colloid adsorption method, the doped carbon-based nano noble metal catalyst is obtained, the introduced doped element phosphorus has anchoring and dispersing effects on noble metal, and the noble metal is more stable in performance. The activity of the catalyst is remarkably improved by introducing a trace amount of second component metal palladium. The catalyst prepared by the invention is simple in synthesis method, high in activity, good in selectivity and excellent in cycling stability, is suitable for preparing parachloroaniline by hydrogenation of parachloronitrobenzene, and has a relatively wide application prospect.

The invention discloses a method for synthesizing a pyrrole compound. The method comprises the following steps: mixing a beta-nitrostyrene compound, an alpha-fluoro-beta-ketone ester compound, cesium carbonate and ethanol, carrying out an addition reaction at 40-60 DEG C, cooling to room temperature after the reaction is finished, adding acetic acid and zinc particles, and carrying out a cyclization reaction at 60-100 DEG C to obtain the pyrrole compound. The method does not need to add a noble metal catalyst and a large number of redox agents, the reaction is carried out under normal pressure, operation is easy and convenient, raw materials are cheap and easy to obtain, and the method is suitable for large-scale production.

The invention relates to the technical field of organic chemical separation, and discloses a nitrobenzene washing and purifying device and method.The device comprises a nitration separator, an alkali washing module and a water washing module which are sequentially connected in series; the nitration separator is a gravity settling tank; the alkali washing module comprises an alkali washing mixer and an alkali washing separator which are connected in sequence; a central pipe with a cavity inside is arranged in an inner cavity of the alkali washing mixer, and spiral sheets and central pipe jet holes are axially distributed outside the central pipe; the alkali washing separator is a fiber reinforced separator; and mixers and separators used by the water washing module and the alkali washing module are the same in structure. The particle coalescer is arranged behind the nitration separator, so that acid entrained in nitrobenzene is separated in an intensified manner; the alkali washing module and the water washing module adopt the combination of an intensified mixing device and a coalescence demulsification separation device, so that sufficient mixing is realized in the acid-base neutralization and nitrobenzene water washing processes, the acid and products of the acid neutralization reaction are further removed, and the purification of nitrobenzene and the consumption reduction of alkali liquor are realized.

The invention discloses a C2 spiro indolone compound as well as a preparation method and application thereof, simple and easily available N-indole connected o-alkynyl nitrobenzene compound is used as a raw material, and the C2 spiro indolone compound is obtained by heating reaction in a solvent under the catalysis of a cheap metal copper catalyst. The C2 spiro indolone compound prepared by the invention has a relatively good inhibition effect on phytopathogen, and can be used for preventing and treating botrytis cinerea, sclerotinia rot of colza and botryosphaeria dothidea; the preparation method does not need to use an expensive metal catalyst, does not need an additional reducing agent, and has the advantages of simple operation, high chemical selectivity, wide reaction substrate range and the like.

The invention relates to a polycarboxylic acid water reducer and a preparation method thereof, and the water reducer is prepared from the following raw materials: 45 to 55 percent of isopentenyl polyoxyethylene ether, 28 to 35 percent of acrylic acid, 1.5 to 2.5 percent of modifier, 0.3 to 0.5 percent of ammonium persulfate, 0.03 to 0.06 percent of ascorbic acid, 5 to 8 percent of hydroxyethyl methylacrylate, 0.15 to 0.25 percent of 2, 4-diphenyl-4-methyl-1-pentene and the balance of water. The modifier is prepared from the following raw materials: 1, 5-dichloronaphthalene, p-nitrostyrene, dimethyl sulfate, ceric ammonium nitrate and tetramethylpiperidine oxide. The polycarboxylate superplasticizer has excellent neat paste fluidity and fluidity retention capability, has low 1h time-dependent variable slump which is below 18mm and optimally 10mm when applied to concrete, has a water-reducing rate of more than 40% and a gas content of less than 3.8%, and also has more advantages in compressive strength ratio.

The invention discloses nearly-spherical silver powder formed by self-assembly of silver nanosheets and a preparation method and application of the nearly-spherical silver powder, and belongs to the technical field of micro-nano material preparation. The preparation method comprises the following steps: firstly, adding a dispersing agent solution into a silver precursor compound solution, stirring, then adding a morphology control agent solution, stirring, and finally adding a reducing agent solution for reaction; and after the reaction is completed, the prepared silver powder is washed and dried, and the nearly-spherical silver powder formed by self-assembly of the silver nanosheets is obtained. The nearly-spherical silver powder is formed through self-assembly of the silver nanosheets, the particle size range of the nearly-spherical silver powder is 0.5-2.0 m, the thickness range of the self-assembled silver nanosheets is 10-50 nm, the overall size is uniform, a large number of stacking faults exist on the surfaces of the silver nanosheets, and the silver nanosheets show an excellent catalytic effect in conversion of p-nitrophenol into p-aminophenol.

The invention relates to the technical field of preparation of N-(2, 4-dinitrophenyl)-4-nitrobenzoyl aniline, in particular to a method for preparing a nitro amide compound by adopting a microreactor. The method for preparing the nitro amide compound comprises the following steps: introducing a sulfuric acid solution of 4-nitro-N-phenylbenzamide and a nitric acid aqueous solution into a microreactor, and reacting to obtain N-(2, 4-dinitrophenyl)-4-nitrobenzamide; the microreactor is provided with at least two reaction modules which are connected in series, and a sulfuric acid solution of 4-nitro-N-phenylbenzamide is divided into at least two strands which are respectively fed into a first reaction module of the microreactor and other reaction modules except the first reaction module; and the nitric acid aqueous solution enters the microreactor in a way of at least one stream. According to the method, the microreactor is used as a reaction carrier, the temperature in the reaction process is controllable, the raw material conversion rate is increased, and the residual amount of an intermediate N-4-nitro-(4-nitrophenyl) benzamide is reduced.

The invention relates to the technical field of synthesis of organic compounds, and discloses a synthesis method of an o-aminoanisole compound, which comprises the following steps: preparing a composite alkali slow-release system consisting of inorganic alkali and organic alkali; preparing a catalytic reduction reaction system containing a metal complex stabilizer, a transition metal catalyst and a hydrophilic ether cosolvent; a catalytic reduction reaction of o-nitroanisole is carried out, and the slow-release alkali-coated material gradually releases the composite alkali to maintain a stable pH environment; after the reaction is completed, adding a packing material rapid digesting agent to remove a packing material structure, and meanwhile, rapidly separating and protecting a product by using a product protective extracting agent and an antioxidant synergistic protective agent; and purifying and recovering the final product to obtain a high-purity o-aminoanisole product. The reaction efficiency, the product purity, the service life of the catalyst and the separation efficiency are comprehensively improved through the synergistic effect of the eight components, the product purity reaches 99.5% or above, the catalyst can be recycled for 5-8 batches, and the separation time is shortened to 0.5-1 hour.

The invention discloses a synthesis method of 5-bromoindole-2-carboxylic acid methyl ester, and the synthesis route comprises the following steps: S1, taking 2-iodo-4-broronitrobenzene and dimethyl malonate as raw materials, and under the catalysis of a solid sulfonic acid resin catalyst, carrying out nucleophilic substitution reaction to prepare 2-(5-bromo-2-nitrophenyl) dimethyl malonate; s2, taking the dimethyl 2-(5-bromo-2-nitrophenyl) malonate prepared in the step S1 as a raw material, taking a ZSM-5 molecular sieve loaded with cobalt acetate as a catalyst, and introducing hydrogen for reduction reaction to prepare a 5-bromoindole-2-carboxylic acid methyl ester crude product; and S3, carrying out recrystallization on the 5-bromoindole-2-carboxylic acid methyl ester crude product prepared in the step S3 by using ethanol, so as to prepare a 5-bromoindole-2-carboxylic acid methyl ester pure product. The synthesis yield is relatively high, the environmental protection property is relatively good, and the prepared 5-bromoindole-2-carboxylic acid methyl ester is relatively excellent in quality and relatively low in cost.

The invention discloses a high-strength energetic compound based on a polydopamine and thiourea polymer and a preparation method of the high-strength energetic compound, and the energetic compound is composed of energetic crystal 1, 3, 5-triamino-2, 4, 6-trinitrobenzene, the polydopamine and the thiourea polymer. The preparation method comprises the following steps: modifying an energetic crystal 1, 3, 5-triamino-2, 4, 6-trinitrobenzene through polydopamine in advance; the polythiourea is obtained through reaction of 2, 2 '-(ethylene dioxygen) diethylamine, carbon disulfide and trimethylolpropane tripolypropylene glycol ether, and the addition amount is 2.5 wt.%-10 wt.%; and mixing the two components by a kneading method, and drying to obtain the energetic compound. The obtained compound has the characteristics of strengthening and toughening, the Brazil mechanical strength reaches 14.76 MPa, and the fracture strain reaches 0.474%. By introducing polyphenol polydopamine and polythiourea to achieve a synergistic effect, the mechanical property of the explosive is greatly improved, and a technical support can be provided for the application of the explosive; meanwhile, the preparation method is simple, mild in reaction condition and easy for large-scale production.

The invention discloses a method for synthesizing p-aminophenol through electrolytic reduction, which comprises the following steps: carrying out electrolysis by adopting a diaphragm electrolytic cell and taking an oxidation reaction of hydrogen as an anode reaction, taking a reduction reaction of nitrobenzene as a cathode reaction, taking a sulfuric acid aqueous solution as an anode liquid and taking an aqueous solution containing nitrobenzene and sulfuric acid as a cathode liquid, and recycling an electrolysis product in the cathode liquor to obtain the p-aminophenol. According to the invention, the oxidation reaction of hydrogen is used as the anode reaction, a membrane electrode or a gas diffusion electrode is preferably used as the anode, and an iridium oxide anode and a lead anode are not used, so that the cost is effectively reduced or pollution is avoided; the electrolytic reaction is carried out under the condition that the pressure intensity of the anode chamber is not lower than that of the cathode chamber, the electrolytic voltage is reduced by about 1.6-2.3 V (compared with an iridium oxide anode), the energy consumption is obviously reduced, and the yield of p-aminophenol is improved by about 10%.

The invention discloses a method for synthesizing L-γ-glutamyl-3-carboxyl-4-nitroaniline ammonium salt, and relates to the technical field of organic synthesis. According to the invention, Glupa-C is synthesized by using 5-amino-2-nitrobenzoic acid and 3-nitrophthaloyl-L-glutamic anhydride as starting materials through a condensation reaction and a hydrazinolysis reaction under the catalytic action of a Lewis acid. Compared with traditional alkaline preparation conditions, the use of highly toxic reagents and the safety hazard of explosion during the preparation process are avoided, production risks are reduced, and energy consumption is lowered. In addition, the synthesis method provided by the invention can achieve a total yield of 47.8% and a purity of 99.96% for the product Glupa-C, and is suitable for industrial production.