732 results about "Nitration" patented technology

The invention belongs to the technical field of sewage treatment, and particularly relates to an anaerobic ammonia oxidation-photoelectric denitrification deep nitrogen removal method. The method comprises the following steps: firstly, adopting a double-chamber reactor; introducing part of sewage into the cathode chamber, carrying out Anammox reaction under a dark state condition to remove ammonia nitrogen and part of nitrite nitrogen, and synchronously generating nitrate nitrogen; turning on a light source to irradiate the anode chamber, exciting photo-induced electrons by a photosensitizer, transmitting the photo-induced electrons to the cathode chamber through an external circuit, and driving the sulfur autotrophic denitrification sludge to reduce residual nitrite nitrogen and nitrate nitrogen generated by Anammox; the total nitrogen removal rate is close to 100%. According to the invention, photo-induced electrons are used as the only denitrification electron donor, so that the addition of a carbon source / sulfide is thoroughly avoided, and the risk of secondary pollution is eliminated. The method is suitable for green low-carbon deep treatment of sludge digestion liquid and pharmaceutical wastewater high-ammonia-nitrogen low-carbon-nitrogen-ratio sewage.

The invention belongs to the technical field of sewage treatment, and discloses a two-stage MABR-based efficient denitrification system, method and application, the system comprises an MABR-PN / DN reactor, an MABR-PN / A reactor, a peristaltic pump, an aeration hollow fiber membrane module, a carrier, an aeration pump, a gas flowmeter, a pressure gauge and a liquid flowmeter, and the MABR-PN / DN reactor and the MABR-PN / A reactor are arranged along the vertical direction. According to the system, the series design of the MABR-PN / DN and the MABR-PN / A is utilized, the adverse effect of organic matter in sewage on anaerobic ammonia oxidation treatment of high-concentration ammonia nitrogen wastewater is reduced, nitrate nitrogen generated by the MABR-PN / A flows back to the first-stage MABR-PN / DN to achieve denitrification, the denitrification limitation of a single reactor and a single denitrification path is broken through, and the overall total nitrogen removal rate of the system is higher than 90%.

The invention relates to the technical field of synthesis of a polymerization inhibitor DNBP, in particular to an efficient production method of the polymerization inhibitor DNBP, which comprises the following steps: step 1, material preparation: selecting corresponding raw materials, weighing and classifying the raw materials, and dividing the raw materials into three main materials, auxiliary materials and additives, the auxiliary material comprises a sulfonic acid type ion exchange resin catalyst, the additive is an ethanol-water mixed solvent, and during weighing, weighing and proportioning are performed according to the molar ratio of nitric acid to o-tert-butylphenol being 2.15: 1 and the mass ratio of o-tert-butylphenol to carbon tetrachloride being 0.15: 1; according to the method, a gradient temperature control strategy is adopted, and a multi-stage microchannel reactor is combined, so that efficient mass and heat transfer of nitration reaction is realized, deep nitration side reaction is inhibited, the content of dinitro isomer impurities is greatly reduced, meanwhile, the total residence time can be accurately controlled, the explosion risk caused by local overheating in a traditional process is avoided, and the method is suitable for industrial production. The reaction selectivity and the safety are obviously improved.

The invention relates to a particulate composition comprising, or substantially consisting of, urea, an inhibitor, preferably a urease inhibitor and / or a nitrification inhibitor, and an additive, wherein the additive comprises components (i), (ii), and optionally (iii): (i) one or more polyhydric alcohols; preferably one or more carbohydrates, preferably selected from monosaccharides, disaccharides, and oligosaccharides; (ii) a first polymer, preferably an amine-containing polymer; more preferably a polyvinylamine or a polyalkyleneimine; and (ii) optionally, a second polymer, preferably a polar polymer; more preferably a water-soluble polar polymer. The invention further relates to a process for producing the particulate composition, an additive for a particulate composition, and the use of the particulate composition as a fertilizer.

Systems and methods for producing ammonium nitrate are disclosed herein. Exemplary systems can comprise a bioreactor positioned to receive a feed including ammonia. The bioreactor can hold a liquid solution including (i) an ammonia oxidizing bacteria (AOB) and (ii) a nitrite oxidizing bacteria (NOB). The AOB can facilitate oxidation of the ammonia to produce a nitrite at a nitritation rate and the NOB can facilitate oxidation of the nitrite at a nitratation rate. Thus, the bioreactor can produce a mixed liquor comprising a nitrate biologically. The system can further comprise a filter positioned to receive the mixed liquor and produce a permeate and a sludge. A sensor can measure the concentration of the liquid solution of the bioreactor, and a controller coupled to the sensor can regulate the mass flow of nitrogen and / or phosphorus of the bioreactor feed based on the measured concentration of the liquid solution.

The utility model belongs to the technical field of sewage treatment, and relates to a sewage treatment system which comprises a first-stage anoxic tank, a first-stage aerobic tank, a second-stage anoxic tank and a second-stage aerobic tank which are sequentially connected through pipelines, and sludge generated after reaction in the second-stage aerobic tank flows back to the first-stage aerobic tank. Sludge generated after nitrification in a secondary aerobic tank in a wastewater treatment process flows back to a primary aerobic tank for cyclic nitrification, so that the chemical oxygen demand and the total nitrogen load in the sludge are reduced, and the chemical oxygen demand and the total nitrogen in discharged water are reduced; meanwhile, by arranging two-stage anoxic denitrification and two-stage nitration reaction, the nitration and denitrification reaction time is prolonged, the removal rate of ammonia nitrogen and total nitrogen in sewage is increased, the content of ammonia nitrogen and total nitrogen in drained water is reduced, the content of ammonia nitrogen, total nitrogen, chemical oxygen demand and total phosphorus in sewage is further reduced through the synergistic effect, and the emission standard is met.

The invention relates to the technical field of water treatment, and discloses a sludge quality-divided reflux type aerobic-anoxic sulfur autotrophic activated sludge denitrification process. The process comprises the following steps: wastewater enters a sectional type aerobic tank, the wastewater enters the sectional type aerobic tank, organic matters are removed in a strengthened manner in a first section of aerobic tank, part of ammonia nitrogen is converted into nitrite nitrogen and nitrate nitrogen, and nitrification is strengthened in a second section of aerobic tank, so that the ammonia nitrogen is deeply removed; effluent of the sectional type aerobic tank enters an anoxic tank and is completely mixed with sulfur particles and activated sludge for sulfur autotrophic denitrification; effluent of the anoxic tank enters a secondary sedimentation tank for sedimentation, supernate is discharged, and bottom mud enters a hydrocyclone to be divided into heavy sludge and light sludge; the heavy sludge flows back to the front end of the anoxic tank, the light sludge flows back to the front end of the sectional aerobic tank, and the remaining sludge is discharged. According to the invention, sulfur autotrophic denitrification is deeply integrated into an activated sludge system, so that high-efficiency nitrogen removal without carbon source and internal reflux is realized.

The invention belongs to the field of microorganisms, and particularly relates to a high-efficiency denitrification heterotrophic nitrification-aerobic denitrification klebsiella and a culture method and application thereof.A biological material of the high-efficiency denitrification heterotrophic nitrification-aerobic denitrification klebsiella is named as Klebsiella oxytoca CT4 and is preserved in Guangdong Microbial Culture Collection Center (GDMCC) on July 21, 2025, the preservation number of the Klebsiella oxytoca CT4 is CGMCC NO.9687, and the preservation number of the Klebsiella oxytoca CT4 is CGMCC NO.987. The preservation address is Institute of Microbiology, Guangdong Academy of Sciences, on the fifth floor of building 59, No. 100 courtyard, Xianlie Middle Road, Guangzhou, Guangdong Province; the preservation number of the strain is GDMCCNO: 66723; according to the strain, the ammonia nitrogen removal rate can reach 98.7% through nitrification-denitrification, the nitrite accumulation amount in the whole process is lower than 0.5 mg / L, and accumulation of toxic intermediate products is avoided. The strain has wide environmental adaptability, can keep efficient denitrification activity under the conditions that the pH is 5.0-10.0 and the C / N ratio is 5-30, can tolerate fluctuation of wastewater quality, does not need to repeatedly adjust the pH value when being used for treating aquaculture wastewater with a high C / N ratio (greater than 20), and can still stabilize the total nitrogen removal rate to be 80% or above, so that the addition cost in a conventional process is remarkably reduced.

The invention belongs to the technical field of energetic plasticizer preparation, and particularly discloses a method for preparing N-butyl nitroxyethyl nitramine through ionic liquid nitration. The method comprises the following steps: mixing an ionic liquid nitrating agent with butyl ethanolamine to obtain a mixed solution; and mixing the mixed solution with a catalyst and acetic anhydride, reacting, and carrying out post-treatment to obtain the N-butyl nitroxyethyl nitramine. According to the method, the ionic liquid with stable properties is adopted as the nitrating agent, the reaction is mild when the ionic liquid is mixed with the butylethanolamine, violent heat release caused when fuming nitric acid is in contact with the butylethanolamine is effectively avoided, and the ionic liquid precursor can be recycled through simple extraction after the reaction.

The pure membrane MBBR sewage treatment system comprises an anoxic denitrification zone, an anaerobic ammonia oxidation zone, an aerobic oxidation zone, a high-density sedimentation zone, an MBBR biological filtration zone, a backwashing water tank and an equipment room, the anoxic denitrification region is used for carrying out amination reaction, organic matter hydrolysis reaction and denitrification reaction on the sewage and nitrate and nitrite in the anoxic denitrification region; the anaerobic ammonia oxidation zone is used for reacting the sewage with nitrite to generate nitrogen; the aerobic oxidation zone is used for promoting microorganisms to degrade organic matters in sewage and convert ammonia nitrogen; the high-density settling zone is used for separating muddy water in sewage; the MBBR biological filtration area is used for filtering suspended matters in the sewage; the backwashing water tank is used for providing backwashing make-up water for the MBBR biological filtration area; and the equipment room is used for placing disinfection equipment, a fan and a power distribution control system.

The invention relates to a sulfur autotrophic denitrification expanded bed and a sewage deep denitrification method thereof, and belongs to the technical field of sewage deep treatment.The sulfur autotrophic denitrification expanded bed comprises a water inlet device, a backflow device water inlet, a backflow device water outlet, a first sampling port, a second sampling port and a water drainage port, and a pebble bed, a filler layer and a clear water layer are arranged in the device from bottom to top; according to the technical scheme, a reinforced filler is loaded through a layered double hydroxide-bentonite composite material, and is combined with hydroxyl polyethylene glycol sulfydryl after being coated with elemental sulfur, so that the modified denitrification filler is obtained; the sulfur autotrophic denitrification expanded bed is filled with the modified denitrification filler, and the change of the expansion rate is realized by optimizing the particle size of the filler and controlling the reflux ratio, which reflects that the filler with smaller particle size can effectively increase the denitrification rate and improve the denitrification efficiency; through the expanded bed process, the removal effect on nitrate nitrogen, ammonia nitrogen and total phosphorus in sewage can be better enhanced, and the denitrification performance of the sulfur autotrophic denitrification expanded bed is improved.

The invention belongs to the technical field of sewage treatment, and particularly relates to a composite carbon source additive and a preparation method thereof. The composite carbon source additive comprises the following components in parts by weight: 30-40 parts of bagasse, 8-12 parts of a polyvinyl alcohol derivative, 2-4 parts of a functional filler, 5-8 parts of potassium citrate and 5-8 parts of sodium pyruvate, the preparation process of the polyvinyl alcohol derivative comprises the following steps: adding polyvinyl alcohol, 1, 3, 5-benzene trisulfonic acid, triethylamine and 4-dimethylaminopyridine into dichloromethane to react, filtering, washing and drying; the polyvinyl alcohol derivative is obtained. The composite carbon source additive can be slowly released in the denitrification process and continuously and stably provide a carbon source, the denitrification process is promoted, and the denitrification efficiency is improved.

The invention particularly relates to a low-carbon robust short-cut nitrification process, which is used for low-carbon treatment of various ammonia-nitrogen-containing wastewater. The device has the characteristics that oxygen is supplied in a manner of combining micro-nano pre-aeration with external circulation, so that the device has higher oxygen supply uniformity, the reaction rate and the DO utilization rate in the short-cut nitrification reactor are greatly improved, meanwhile, accurate oxygen supply is realized, the oxygen supply energy consumption is effectively reduced, and carbon emission is reduced; according to the invention, oxygen is supplied in a manner of combining pre-aeration with external circulation, so that the concentration of DO in the short-cut nitrification reactor is ensured, meanwhile, N2O release caused by bubble disturbance is avoided, N2O emission factors in the short-cut nitrification process are effectively reduced, and low-carbon short-cut nitrification is realized; by coupling alkaline inhibition and salt inhibition, NOB activity is effectively controlled, and long-term stability of short-cut nitrification is realized.

The invention discloses a method for realizing deep autotrophic nitrogen removal of sludge digestion liquid based on alternate intermittent aeration of a double-membrane aeration bio-membrane reactor (MABR). The process device comprises a sludge digestion liquid raw water tank, a single-stage double-MABR reactor, two MABR devices and a water outlet tank. According to the method, sludge digestion liquid enters the single-stage double-MABR reactor, the two MABR devices are alternately and intermittently aerated, the state of one aeration and one aeration stopping is always kept, and ammonia nitrogen in raw water is converted into nitrite through ammonia oxidizing bacteria enriched on the inner side of an MABR membrane. And simultaneously supplying to anaerobic ammonium oxidation bacteria enriched on the outer sides of the two MABR membranes through matrix diffusion for denitrification and generation of nitrate. Denitrifying bacteria enriched on the outer side of the MABR membrane utilize raw water organic matters to drive short-cut denitrification to synchronously supply nitrite to anaerobic ammonium oxidation bacteria so as to realize deep autotrophic nitrogen removal. According to the invention, a double-anaerobic ammonia oxidation reaction hot area is constructed through alternate intermittent aeration of double MABRs, and efficient deep autotrophic nitrogen removal of the sludge digestion liquid can be stably realized.

The invention discloses an anti-leaching nutrient slow-release synergistic compound fertilizer, and particularly discloses an anti-leaching nutrient slow-release synergistic compound fertilizer and a preparation method thereof. The compound fertilizer comprises the following components in parts by weight: 30-50 parts of urea particles, 15-25 parts of monoammonium phosphate, 20-30 parts of potassium sulfate, 2-5 parts of a slow-release synergistic coating agent, 1-3 parts of a bonding wrapping layer and 10-20 parts of a filling material. The slow-release synergistic coating agent comprises polyaspartic acid (PASP) and a composite inhibitor (a urease inhibitor and a nitrification inhibitor), and the bonding wrapping layer is made of a polyvinyl alcohol / sodium polyethylene acid-based cementing material. The preparation method comprises the following steps: mixing and granulating raw materials, carrying out primary coating (slow-release synergist), carrying out secondary coating (bonding a coating layer), and drying and screening. Through the synergistic effect of the double coating technology and the compound inhibitor, the nitrogen conversion and release are obviously delayed, the nutrient leaching loss is reduced by 20-40%, the fertilizer utilization rate is improved by 25-30%, and the compound fertilizer is suitable for high-temperature and rainy areas.

The application provides a method for continuously preparing nitrobenzene by using benzene and NO2 as raw materials. The method is characterized in that: a solid catalyst capable of catalyzing the nitration of benzene by NO2 is filled in a pipe reactor, benzene, NO2 and O2 are continuously fed into the pipe reactor at a certain flow rate, and the reaction is carried out at a certain temperature to obtain nitrobenzene. This route is safe, green, economical and efficient, and is a safe, green, economical and efficient nitrobenzene synthesis route.

The invention discloses an asphalt-based double-salt template porous carbon electrode material as well as a preparation method and application thereof, and relates to the technical field of porous carbon electrode materials. The preparation method sequentially comprises the following steps: adding asphalt into concentrated nitric acid, stirring for reaction, and washing to obtain a nitration product; and uniformly mixing the nitration product, active organic potassium salt and inert inorganic carbonate, performing ball milling, then performing pre-oxidation and carbonization treatment, and washing to be neutral to obtain the asphalt-based double-salt template porous carbon electrode material. The invention also discloses the asphalt-based double-salt template porous carbon electrode material and application of the asphalt-based double-salt template porous carbon electrode material in removal of nitrate radicals and ammonia nitrogen in a water body through a capacitive deionization technology. According to the invention, a macropore-mesopore-micropore synergistic hierarchical pore structure is constructed in an asphalt carbon skeleton through a double-salt template, efficient adsorption of two nitrogen pollutants of nitrate and ammonia nitrogen is realized, and the method has important practical application value.

The invention relates to a method for improving resistance of a denitrification strain to a new pollutant perfluorinated compound, and belongs to the field of biological denitrification of sewage. The method comprises the following steps: under an aerobic condition, culturing a denitrification strain by using a sterilized TSB culture medium to obtain OD600 = 1.8; resuspending with a sterile PBS buffer solution to obtain a bacterial suspension; (2) preparing a synchronous nitrification and denitrification culture medium, and sterilizing for later use; (3) respectively adding a perfluorinated compound into the synchronous nitrification and denitrification culture medium, and respectively inoculating the bacterial suspension in the step (1) into the synchronous nitrification and denitrification culture medium containing the perfluorinated compound according to the inoculum size of 1% (v / v); and (4) placing the inoculated synchronous nitrification and denitrification culture medium in an aerobic environment, culturing for 2 hours in a shaking table at the temperature of 30 DEG C and the rotating speed of 150rpm, and carrying out weak ultrasonic treatment on the strain by using an ultrasonic generator. According to the method, the denitrification strain is treated by weak ultrasound, so that the inhibition effect of the perfluorinated compound on the denitrification strain is slowed down, and the resistance of the denitrification strain on the perfluorinated compound is improved.

The present invention belongs to the field of biomedicine, and specifically relates to a light-controlled release of ONOO － Compounds and preparation methods and applications thereof. The present invention provides ONOO ‑ The donor is composed of a diphenyl phenothiazine analogue and arginine covalently linked. Its strong conjugation effect makes it extremely photoresponsive. The polymer has near-infrared light emission and excellent reactive oxygen and reactive nitrogen generation capabilities. When L6 is irradiated with a 660nm laser, it will produce superoxide anions and singlet oxygen. Singlet oxygen oxidizes the guanidine group of arginine to produce NO and ·O2 ‑ and NO to form peroxynitrite (ONOO ‑ ), achieving the goal of highly effective tumor cell killing. Therefore, this compound is a potentially highly effective photosensitizer for tumor killing. Compared to conventional photosensitizers, this killing method has stronger oxidative and nitrative cell damage capabilities, and its development cycle is shorter than that of other photosensitizers, thus possessing great potential application value in clinical treatment.

The invention relates to a method for preparing an intermediate for synthesis of olpinapone. The method comprises the step of nitrating vanillic acid in anhydride by using a nitrating agent. The present invention also relates to an intermediate for the synthesis of olpiapone produced by this process. In addition, the present invention relates to a solution of an intermediate for the synthesis of olpiapone in an anhydride.

The invention relates to the technical field of environmental microbial resource development and sewage denitrification. The invention discloses an efficient denitrification strain Paracoccus sp.N21 with a flocculation characteristic, which is preserved in the China General Microbiological Culture Collection Center (CGMCC), and the preservation number is CGMCC No.34710. The invention further discloses a preparation method of the efficient denitrification strain Paracoccus sp.N21. The strain obtained by the invention can completely remove ammonia nitrogen within 12 hours and thoroughly remove nitrate nitrogen within 48 hours, the removal rate reaches 100%, and ammonia nitrogen is preferentially degraded in a mixed nitrogen source. The method has the unique advantages that the flocculation rate in the nitrification process and the flocculation rate in the denitrification process exceed 93.9%, and the usage amount of a flocculating agent can be greatly reduced. When actual kitchen wastewater is treated, the ammonia nitrogen removal rate reaches 100%, and the removal rate reaches up to 7.51 mg / (L.h). The application of the strain can effectively reduce the volume of a reactor, reduce energy consumption and operation cost, provides a new solution for simplifying a biological denitrification process, is particularly suitable for treating high-ammonia-nitrogen kitchen wastewater, and has remarkable environmental and economic benefits.

The application provides a synthesis method of p-benzoquinone dioxime. The synthesis method comprises the following steps: (1) adding solid acid into an ethanol solution of phenol to obtain a mixed solution A, then vacuumizing and filling with inert gas; dissolving nitrite into ethanol, uniformly mixing to obtain an ethanol solution of nitrite, then vacuumizing and filling with inert gas; in an inert gas atmosphere, adding the ethanol solution of nitrite into the mixed solution A dropwise to perform nitrosation reaction, to obtain a reaction liquid B; in the inert gas atmosphere, adding an ethanol solution of hydroxylamine into the obtained reaction liquid B to perform oximation reaction; after the reaction is completed, filtering the obtained reaction liquid C, performing reduced pressure distillation on the obtained filtrate, and performing washing, filtering and drying on the obtained residual liquid of the reduced pressure distillation, to obtain p-benzoquinone dioxime. The method provided by the application reduces the occurrence of side reactions, improves the conversion rate of the reaction, and improves the yield and purity of p-benzoquinone dioxime.

The invention discloses a preparation method of 6-nitro-m-cresol, and belongs to the technical field of organic synthesis.The method comprises the steps that raw materials are subjected to esterification, water washing, sulfonation, nitration, desulfonation and refining in sequence, and the 6-nitro-m-cresol is obtained. According to the method, it can be guaranteed that the intermediate product is the 6-nitro derivative, generation of isomer impurities such as 2-site and 4-site is greatly reduced from the source, the reaction path is clear, and atom economy is good. The method does not need to depend on complicated means such as time-consuming column chromatography or precise fractionation, the requirement for high purity can be met only through conventional extraction and crystallization operation, the technological process is simple, the method is very suitable for large-scale production, and the product purity (measured through HPLC (High Performance Liquid Chromatography)) can stably reach 98% or above.

The present invention provides a tower-type denitrification reaction device and process for landfill leachate, comprising a UASB reactor, a nitrification tank, a material mixer, and a denitrification tower. The UASB reactor is provided with a gas-liquid separation device to separate materials generated by landfill leachate in the reactor into waste gas and waste liquid. The waste liquid is input into the nitrification tank, which is provided with an ammonia nitrogen detector and a nitric nitrogen and total nitrogen detector. The nitrification tank is linked with an aeration device of the nitrification tank through a PLC control program to achieve intelligent control of the air intake of the aeration device, thereby saving fan energy consumption and reducing labor waste. The waste liquid discharged from the nitrification tank and the waste gas discharged from the UASB reactor are mixed in the material mixer and then discharged into the denitrification tower. The waste gas plays a stirring role in the denitrification reaction, effectively increasing the denitrification reaction rate. The denitrification tower is provided with a nitrate nitrogen separation device to separate residual nitrate nitrogen. The separated nitrate nitrogen is refluxed to the UASB reactor to react with the landfill leachate, thereby achieving full utilization of the carbon source.

The invention relates to the field of chemical equipment, in particular to a 1-nitroanthraquinone continuous production process based on a dynamic liquid membrane continuous flow reactor, which comprises a solid feeding device, a homogeneous emulsifier, a quenching kettle, a solid-liquid separator, a centrifugal separator and a dynamic liquid membrane reactor, a sulfuric acid storage tank is divided into two branches through a sulfuric acid feeding pump, one branch is connected to the dynamic liquid membrane reactor, the other branch is connected to the dynamic liquid membrane reactor through a flow self-control valve, the quenching kettle is connected to a solid-liquid separator, the solid-liquid separator is divided into two branches, one branch is connected to an anthraquinone crude product storage tank, the other branch is connected to a centrifugal separator, and the other branch is connected to a gas-liquid separator. The centrifugal separator is divided into two branches, one branch is connected to the acid water storage tank, and the other branch is connected to the dichloroethane storage tank, so that the reaction selectivity of the anthraquinone nitration reaction can be effectively improved, high-viscosity solids are prevented from being blocked, and the conversion rate of raw materials in the continuous reaction of the anthraquinone nitration reaction is improved.

The present application relates to the technical field of microorganism, and provide a kind of low temperature resistant nitrosomonas and its application.The nitrosomonas is nitrosomonas (Nitrosomonas europaea.) H1, and the preservation number is CCTCC NO:M 2024693.The nitrosomonas H1 of the present application has the characteristics of low temperature resistance, grows well at 10 DEG C, and has good ammonia oxidation capacity, is suitable for the treatment of northern winter low temperature wastewater, and does not need to be heated or take other measures to maintain the stability of biochemical system.

Fertilizers with urease inhibitors and / or nitrification inhibitors are described. The fertilizer can include an extruded granule containing urea, a polymeric binder, and a nitrification inhibitor and / or an urease inhibitor.

The invention discloses a synthesis method of 5-(1H-pyrrole-1-yl)-2-mercaptobenzimidazole, which comprises the following steps: carrying out cyclization condensation reaction on o-phenylenediamine and thiourea in an acidic environment provided by hydrochloric acid to obtain 2-mercaptobenzimidazole; the preparation method comprises the following steps: carrying out nitration reaction on 2-mercaptobenzimidazole, sulfuric acid and nitric acid to obtain 2-mercapto-5-nitrobenzimidazole; the preparation method comprises the following steps: carrying out nitro reduction reaction on 2-sulfydryl-5-nitrobenzimidazole and hydrogen under the catalysis of nickel to obtain 5-amino-2-sulfydryl benzimidazole; the preparation method comprises the following steps: carrying out an N-alkylation reaction on 5-amino-2-mercapto benzimidazole and tetrahydro-2, 5-dimethoxyfuran under the catalysis of copper chloride to generate 5-(1H-pyrrole-1-yl)-2-mercapto benzimidazole, and carrying out a reaction on the 5-amino-2-mercapto benzimidazole and tetrahydro-2, 5-dimethoxyfuran to generate the 5-(1H-pyrrole-1-yl)-2-mercapto benzimidazole. The method disclosed by the invention has the outstanding advantages of mild and easily-controlled conditions, simple and convenient post-treatment, high yield, economy, environmental protection, suitability for large-scale production and the like, conforms to the green chemical development concept, and has important application value.

The invention discloses a method for preparing nitro-mesitylene through a micro-channel nitration reaction. The method comprises the following steps: respectively conveying mesitylene, fuming nitric acid and sulfuric acid to a micro-channel reaction module through a metering pump, and completing nitration reaction within a retention time of tens of seconds to several minutes. The introduction sequence of nitration reaction materials, the reaction retention time and the reaction temperature are cooperatively controlled, the nitration reaction is completed in the microchannel reactor in a continuous flow mode, operation is easy and convenient, safety is high, efficient continuous production can be achieved, meanwhile, emission of three wastes is reduced, and the industrial application advantages of being environmentally friendly and economical are achieved.