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3results about How to "Avoid death" patented technology

Construction method of spontaneous mouse brain edema model and application thereof

ActiveCN119586586BSpontaneous cerebral edemaSmall individual differencesCompounds screening/testingMicrobiological testing/measurementDiseasePhysiology
This invention relates to animal models and their applications, specifically to a method for constructing a spontaneous mouse cerebral edema model and its application. This invention utilizes PEN2... fl / + Mice and PEN2 fl / + Mice were mated to obtain PEN2. fl / fl Homozygous mice; then the obtained PEN2 fl / fl Mice and hGFAP Cre / + Mice were mated to obtain PEN2. fl / + hGFAP Cre / + Mice; the final PEN2 obtained fl / + hGFAP Cre / + Mice and PEN2 fl / fl Mice were mated to obtain PEN2. fl / fl hGFAP Cre / + The mouse model is a spontaneous mouse cerebral edema model. In this model, PEN2 protein levels are significantly downregulated, and the mouse exhibits a severe cerebral edema phenotype. This model can be used to establish a cerebral edema drug screening platform. It can also be used for research on cerebral edema-related diseases, such as the pathogenesis of cerebral edema caused by infection, glioma, and traumatic brain injury, as well as for the development of technologies and products for the diagnosis and treatment of related diseases.
Owner:NANJING DRUM TOWER HOSPITAL

A multifunctional cell culture multiwell plate for electroporation

PendingCN122278624AImprove practicalityavoid deathBiomedical engineeringMultiwell plate
This application relates to the field of cell electroporation technology, and provides a multifunctional cell culture multiwell plate for electroporation, including a consumable cover, a consumable interlayer, and a consumable base plate. The top surface of the base plate has multiple wells for containing cell solutions. The consumable interlayer is located on top of the base plate, and a cavity for containing cell solutions is formed between the consumable interlayer and the base plate. Electrode slots are provided on the consumable interlayer at positions corresponding to both sides of each well. The consumable cover is located on top of the interlayer, and a removable electrode is provided on the cover at a position corresponding to each electrode slot. An impedance detection electrode assembly is provided on the bottom surface of the base plate at a position corresponding to each well. This application improves the practicality of the multifunctional cell culture multiwell plate.
Owner:DALIAN BOJIAN BIOTECHNOLOGY CO LTD

A fish fry screening device for aquaculture

ActiveCN224522119Uachieve shakingFlexible adjustment of shaking range
The utility model provides a kind of fry screening device for aquaculture, it is related to aquaculture technical field, including organism, the inside of the organism is provided with adjustable shaking screening mechanism, the side of the organism is provided with humidification mechanism, the other side of the organism is equipped with PLC controller, the wiring end of the PLC controller is connected with device inner wire arrangement.This utility model in, by setting adjustable shaking screening mechanism, first servo motor drives the rotation of one-way screw rod, moves the moving block under the restriction of first limit rod, further let rack drive gear and rotating rod rotate, realize that screen cylinder shakes, simultaneously, second servo motor drives the rotation of two-way screw rod, can adjust the interval of two adjusting plate and contact sensor, when moving block touches contact sensor, will feedback signal to PLC controller, control first servo motor reverses, to this flexible adjustment screen cylinder shaking range, solved the problem that existing device cannot flexibly adjust shaking range.
Owner:ANHUI CHUANGYUAN AGRI DEV CO LTD