100205results about How to "Reduce in quantity" patented technology

Conductive layers having knots are adjacently formed with uniform distance therebetween. Droplets of the conductive layers are discharged to stagger centers of the droplets in a length direction of wirings so that the centers of the discharged droplets are not on the same line in a line width direction between the adjacent conductive layers. Since the centers of the droplets are staggered, parts of the conductive layers each having a widest line width (the widest width of knot) are not connected to each other, and the conductive layers can be formed adjacently with a shorter distance therebetween.

To provide a semiconductor device and a display device which can be manufactured through a simplified process and the manufacturing technique. Another object is to provide a technique by which a pattern of wirings or the like which is partially constitutes a semiconductor device or a display device can be formed with a desired shape with controllability.

An electro-mechanical surgical device, system and / or method may include a housing, at least two opposing jaw, and at least one electrical contact associated with at least one of the jaws. The electrical contact may include at least one of a bipolar electrical contact and an ultrasonic electrical contact. The electrical contact may be a row of electrodes located on one or all of the jaws. A sensor may also be associated with any tissue located between the jaws to sense and report the temperature of that tissue. A piercable ampulla containing fluid may also be placed on at least one of the jaws so that the fluid is releasable when the jaws are in closed position and the electrode(s) pass through the tissue into the piercable ampulla.

In a semiconductor device, and a method of manufacturing thereof, the device includes a substrate of single-crystal semiconductor material extending in a horizontal direction and a plurality of interlayer dielectric layers on the substrate. A plurality of gate patterns are provided, each gate pattern being between a neighboring lower interlayer dielectric layer and a neighboring upper interlayer dielectric layer. A vertical channel of single-crystal semiconductor material extends in a vertical direction through the plurality of interlayer dielectric layers and the plurality of gate patterns, a gate insulating layer being between each gate pattern and the vertical channel that insulates the gate pattern from the vertical channel.

Devices and methods for determining analyte levels are described. The devices and methods allow for the implantation of analyte-monitoring devices, such as glucose monitoring devices that result in the delivery of a dependable flow of blood to deliver sample to the implanted device. The devices include unique architectural arrangement in the sensor region that allows accurate data to be obtained over long periods of time.

A method for enabling users to exchange group electronic mail by establishing individual profiles and criteria, for determining personalized subsets within a group. Users establish subscriptions to an electronic mailing list by specifying user profile data and acceptance criteria data to screen other users. When a user subscribes, a web server establishes and stores an individualized recipient list including each matching subscriber and their degree of one-way or mutual match with the user. When the user then sends a message to the mailing list, an email server retrieves 100% her matches and then optionally filters her recipient list down to a message distribution list using each recipient's message criteria. The message is then distributed to matching users. Additionally, email archives and information contributions from users are stored in a database. A web server creates an individualized set of web pages for a user from the database, containing contributions only from users in his recipient list. In other embodiments, users apply one-way or mutual criteria matching and message profile criteria to other group forums, such as web-based discussion boards, chat, online clubs, USENET newsgroups, voicemail, instant messaging, web browsing side channel communities, and online gaming rendezvous.

A medical apparatus and method useful for positioning one or more members within the gastro-intestinal tract is disclosed. The medical apparatus can include a track supported on a sheath sized to receive an endoscope, and a carrier slidable with respect to the track. A feeding tube accessory adapted to slidably engage the carrier is disclosed.

A device for dispensing an individual plastic fastener from a supply of fastener stock to couple together two or more objects. The supply of fastener stock includes a plurality of equidistantly spaced cross links which are coupled at one end to a continuous side rail. The fastener dispensing device includes a hollowed sharpened needle shaped to define a longitudinal bore and a feed mechanism for advancing the continuous side rail of the fastener stock into direct axial alignment behind the longitudinal bore of the hollowed needle. The feed mechanism includes a rotatably mounted feed shaft, a pair of feed wheels fixedly mounted on the feed shaft, each feed wheel comprising a plurality of sprockets which are sized and shaped to engage the supply of fastener stock, and first and second clutch wheels which are releasably matingly engageable with one another, the first clutch wheel being fixedly mounted on the feed shaft and the second clutch wheel being rotatably mounted on the feed shaft, each of the first and second clutch wheels including a plurality of ratchets. As a feature of the invention, the number of ratchets on each clutch wheel is at most equal to the number of sprockets on each feed wheel.

A virtual assistant uses context information to supplement natural language or gestural input from a user. Context helps to clarify the user's intent and to reduce the number of candidate interpretations of the user's input, and reduces the need for the user to provide excessive clarification input. Context can include any available information that is usable by the assistant to supplement explicit user input to constrain an information-processing problem and / or to personalize results. Context can be used to constrain solutions during various phases of processing, including, for example, speech recognition, natural language processing, task flow processing, and dialog generation.

The present device provides an apparatus for securely positioning a medical instrument relative to a patient. The apparatus comprises a drive assembly for moving the medical instrument along a first axis that is substantially parallel to the length of the instrument; an adapter comprising an elongated member and a pair of cooperating hubs for connecting the drive assembly to a positioning system. The cooperating hubs serving to allow separation of sterile from non sterile components. The positioning system comprises two motors each for moving the instrument about a different axis than the drive assembly. The apparatus moving the instrument about a point which is external to the patient. The device further comprises a sterile bag which encloses the positioning system, the bag having at least one opening for receiving an axel from a sterile adapter assembly, thereby rendering the entire apparatus sterile.

Exploiting the substantive reciprocity of internode channel responses through dynamic, adaptive modification of receive and transmit weights, enables locally enabled global optimization of a multipoint, wireless electromagnetic communications network of communication nodes. Each diversity-channel-capable node uses computationally efficient exploitation of pilot tone data and diversity-adaptive signal processing of the weightings and the signal to further convey optimization and channel information which promote local and thereby network-global efficiency. The preferred embodiment performs complex digital signal manipulation that includes a linear combining and linear distribution of the transmit and receive weights, the generation of piloting signals containing origination and destination node information, as well as interference-avoiding pseudorandom delay timing, and both symbol and multitione encoding, to gain the benefit of substantive orthogonality at the physical level without requiring actual substantive orthogonality at the physical level.

A medical stapler is provided with a sterilized cartridge removably attached to a stapler body 1 and accommodating a predetermined number of staples 9, a driving mechanism for driving a staple 9 supplied to a driving section at the tip of the cartridge, a manipulating lever 2 for actuating the driving mechanism and a counter device 20. The counter device 20 counts the number of staples 9 driven from the driving mechanism and indicates the counted result.

Methods and systems for endovascular, endocardiac, or endoluminal approaches to a patient's heart to perform surgical procedures that may be performed or used without requiring extracorporeal cardiopulmonary bypass. Furthermore, these procedures can be performed through a relatively small number of small incisions. These procedures may illustratively include heart valve implantation, heart valve repair, resection of a diseased heart valve, replacement of a heart valve, repair of a ventricular aneurysm, repair of an arrhythmia, repair of an aortic dissection, etc. Such minimally invasive procedures are preferably performed transapically (i.e., through the heart muscle at its left or right ventricular apex).

A system for performing in vivo procedures is provided. The system may include a tool for performing an in vivo procedure. The tool may have an in vivo sensor for obtaining in vivo information; a functional element for performing an interventional or diagnostic in-vivo procedure; a processor in communication with the tool for receiving and optionally processing the in vivo information obtained by the tool and a monitor in communication with the processor for displaying the optionally processed in vivo information. The communication between the elements of the system may be wireless, or, optionally, wired.

An apparatus facilitating the delivery of electrical stimulation to physiologically excitable retinal nerve cells includes: (a), a receiver / decoder / stimulator comprising a semiconductor integrated circuit and other components hermetically sealed within a capsule, implanted and fixed within the eye of the patient such that it may receive power, and decode information from (b), an externally worn image processor / encoder / transmitter comprising an image detector, an image processor capable of translating the image into an array of discreet pixels of varying intensity, encoding the pixel information into a series of discreet data bursts representing the chosen current amplitude, pulse duration, stimulating electrode or electrodes, and reference electrode or electrodes, and transmitting this data to the receiver / decoder / stimulator through a tuned, inductive communication link such that the system may deliver controlled, charge balanced, diphasic, constant current stimulus pulses to (c), discreet metallic electrodes on a flexible, multiple site electrode array implanted on, near or under the surface of the retina. The apparatus provides for flexibility in the external image processing system such that future advancements in processing techniques shall not require revision surgery or modification to the implanted receiver / decoder / stimulator. Safeguards to protect the patient from the delivery of inappropriate stimulus are incorporated into the apparatus, and a method of external collection of diagnostic data from the implanted receiver / decoder / stimulator is described.

A conversational, natural language voice user interface may provide an integrated voice navigation services environment. The voice user interface may enable a user to make natural language requests relating to various navigation services, and further, may interact with the user in a cooperative, conversational dialogue to resolve the requests. Through dynamic awareness of context, available sources of information, domain knowledge, user behavior and preferences, and external systems and devices, among other things, the voice user interface may provide an integrated environment in which the user can speak conversationally, using natural language, to issue queries, commands, or other requests relating to the navigation services provided in the environment.

Improved duplicate and near-duplicate detection techniques may assign a number of fingerprints to a given document by (i) extracting parts from the document, (ii) assigning the extracted parts to one or more of a predetermined number of lists, and (iii) generating a fingerprint from each of the populated lists. Two documents may be considered to be near-duplicates if any one of their fingerprints match.

The present invention provides an acoustic vibration analyzing apparatus for carrying out acoustic vibration analysis by picking up data of sounds generated due to rotation of a plurality of gears and data of the number of revolutions of a gear selected from a plurality of gears when a transmission of a vehicle having the plurality of gears operates. The acoustic vibration analyzing apparatus comprises an acoustic vibration calculation portion for analyzing acoustic data in terms of frequency, an order calculation portion for calculating an order in compliance with the specifications of a plurality of gears, a speed calculation portion for calculating the speed of a vehicle, and a display unit for displaying acoustic pressure levels with the order and vehicle speed associated therewith.

The invention relates to a method of preparing heteromultimeric polypeptides such as bispecific antibodies, bispecific immunoadhesins and antibody-immunoadhesin chimeras. The invention also relates to the heteromultimers prepared using the method. Generally, the method provides a multispecific antibody having a common light chain associated with each heteromeric polypeptide having an antibody binding domain. Additionally the method futher involves introducing into the multispecific antibody a specific and complementary interaction at the interface of a first polypeptide and the interface of a second polypeptide, so as to promote heteromultimer formation and hinder homomultimer formation; and / or a free thiol-containing residue at the interface of a first polypeptide and a corresponding free thiol-containing residue in the interface of a second polypeptide, such that a non-naturally occurring disulfide bond is formed between the first and second polypeptide. The method allows for the enhanced formation of the desired heteromultimer relative to undesired heteromultimers and homomultimers.

Methods of treating cancer and infectious diseases utilizing a treatment regimen comprising administering a compound that reduces inhibitory signal transduction in T cells, in combination with a potentiating agent, such as cyclophosphamide, to produce potent T cell mediated responses, are described. Compositions comprising the PD-1 antagonists and potentiating agents useful in the methods of the invention are also disclosed.

In electrophoretic media, it is advantageous to use pigment particles having about 1 to 15 percent by weight of a polymer chemically bonded to, or cross-linked around, the pigment particles. The polymer desirably has a branched chain structure with side chains extending from a main chain. Charged or chargeable groups can be incorporated into the polymer or can be bonded to the particles separately from the polymer. The polymer-coated particles can be prepared by first attaching a polymerizable or polymerization-initiating group to the particle and then reacting the particle with one or more polymerizable monomers or oligomers.

A method and apparatus for communicating with and monitoring the operation of a device implanted within a patient. A transceiver capable of being implanted within a patient provides a communication interface between an implanted medical device and a monitor external to the patient's body. The external monitor can communicate with a remote monitoring center over a communication network. The external monitor also provides control signals to the implanted device via the transceiver unit. The transceiver apparatus is capable of two-way communication between the implanted device and the external monitor. The transceiver apparatus is also capable of detecting actions performed by the implanted device and physiological signals directly from the patient's body. Thus, the transceiver apparatus provides circuitry for determining whether an implanted medical device is operating properly. The transceiver apparatus provides a way to remotely reprogram one or more implanted medical devices.

There is disclosed a radio communication system in which a constitution of a base station and further a control station can be simplified. A radio communication system according to the present invention converts a received signal received by a plurality of antenna elements in a base station to a signal of different frequency band, and then conflates the converted signal in order to generate sub-carrier wave multiplex signal. The signal is converted to an optical signal, and then the optical signal is transmitted to a control station via an optical fiber. Or the control station performs weighting to phase of the transmitted signal transmitted from a plurality of antennas of a base station, and then performs frequency conversion to different frequency band, and then conflates the converted signal in order to generate the sub-carrier wave multiplex signal. The signal is converted to an optical signal, and then an optical signal is transmitted to the base station side via the optical fiber. The control station and the base station divides the received sub-carrier wave multiplex signal by each frequency band, and then the frequency of the divided signals are converted to the same frequency band in order to generate the transmitted / received signal of each antenna element. By such a constitution, it is possible to reduce constituent of the optical transmission components to the minimum and to simplify the constitution of the base station. Furthermore, it is possible to maintain the relative phase difference and the relative intensity of the transmitted / received signal of each antenna element. Because of this, it is possible to estimate an arrival direction of the received signal and to control radiation beam pattern of the transmitted signal.

CCRM is a business method and computer software system, to be used by Enterprises selling portfolios of products / services, aiming to optimize the expected value of transactions (or contracts) with consumers or business customers. At a transaction level, CCRM estimates the probability of choice of potential offers by the customer. These offers may be presented alone with possible variation of their attributes (such as price), or in combinations / sets, or in sequences. CCRM calculates the probability of consequent conversion and realization of the sale. Probabilities of choice and conversion are forecasted based on a disaggregated customer choice model, taking into account customer characteristics and stated preferences as well as product / service attributes such as price. Offers are then scored and ranked by expected value based on their revenue, cost and choice probability. Finally, CCRM recommends which offer(s) to present to the customer, at which price(s) and in which display / sequence order, to maximize a business objective function such as the expected value of the transaction / contract.

Devices and methods for determining the concentration of an analyte are provided. Embodiments of the subject devices include analyte monitoring systems that include an analyte sensor capable of providing clinically accurate analyte data without a substantial time delay after operably positioning the sensor in a patient. Embodiments of the subject methods include operably positioning an analyte sensor in a patient and obtaining clinically accurate analyte data without a substantial time delay after the positioning. Also provided are systems and kits for use in analyte monitoring.

Exploiting the substantive reciprocity of internode channel responses through dynamic, adaptive modification of receive and transmit weights, enables locally enabled global optimization of a multipoint, wireless electromagnetic communications network of communication nodes. Each diversity-channel-capable node uses computationally efficient exploitation of pilot tone data and diversity-adaptive signal processing of the weightings and the signal to further convey optimization and channel information which promote local and thereby network-global efficiency. The preferred embodiment performs complex digital signal manipulation that includes a linear combining and linear distribution of the transmit and receive weights, the generation of piloting signals containing origination and destination node information, as well as interference-avoiding pseudorandom delay timing, and both symbol and multitone encoding, to gain the benefit of substantive orthogonality at the physical level without requiring actual substantive orthogonality at the physical level.

Described herein is a system for executing distributed transactions. A coordinator and one or more participants cooperate to execute a distributed transaction, the distributed transaction including for each participant a transaction executed by the participant. To manage the transaction, the coordinator and the participant communicate over a network using, for example, a stateless protocol. Before each participant commits the transaction, the participants determine that the coordinator has committed the transaction. The coordinator commits the transaction after receiving acknowledgment from all the participants that they will commit the transaction. To determine whether the coordinator has committed the transaction, a participant transmits a message to the coordinator to acknowledge that it will commit the distributed transaction. The participant commits its respective transaction if it receives an acknowledgement from the coordinator. For the particular transaction being executed by a participant, the participant prevents other transactions from modifying a data item affected by the particular transaction. The participant will prevent such modifications until termination criteria for the particular transaction is satisfied, in which case the participant terminates the transaction.