43 results about "Cardiopulmonary bypass" patented technology

A removable vascular filter system for capture and retrieval of emboli while allowing continuous perfusion of blood during a cardiopulmonary bypass procedure, comprising a porous filter membrane with variable diameter holes, and a filter membrane support structure. The system may minimize the incidence of stroke, myocardial infarction or other clinical complications that may be associated with cardiopulmonary bypass procedures.

A method and system for performing a cardiopulmonary bypass procedure are provided. The method includes accessing a source of blood in a patient body from which source the blood is to be passed through a cardiopulmonary bypass machine, drawing blood from the source through the cardiopulmonary bypass machine and introducing the blood into an aortic artery of the patient body through a plurality of separate passages, after the blood has been passed through the cardiopulmonary bypass machine. The system includes a cardiopulmonary bypass machine, a tubular member coupled to an outlet port of the cardiopulmonary bypass machine and a plurality of separate needle members connected in fluid flow communication with the tubular member, the needle members being arranged to be connected in fluid flow communication with an aortic artery, during a cardiopulmonary bypass procedure.

A customizable and intuitive user interface for medical systems and devices, such as cardiopulmonary bypass systems, perfusion systems, extracorporeal circulation apparatuses, and heart-lung machines, is provided, which allows for ease of access to critical patient data to facilitate blood perfusion and to monitor and regulate various physiological parameters of a patient and an extracorporeal blood flow circuit during surgical procedures, such as cardiopulmonary bypass and extracorporeal membrane oxygenation (ECMO).

The present invention relates to devices and systems that alter intracranial compliance, cerebral blood flow and/or intracranial pressure pulsatility/waveform by oscillating the contraction and expansion of a compressible composition within the cranial or spinal cavities such that they increase intracranial capacity. The contraction and expansion of the compressible composition in the oscillating compliance devices can be due to an individual's intracranial pressure, the result of the expansion and compression of a reservoir which is mediated by the contractility of the heart or driven by a pump gaited to a biorhythm. The invention also relates to methods for protecting an individual's brain from abnormal arterial pulsations and for altering an individual's cerebral blood flow using the devices and systems of the invention. The oscillating compliance devices can be used to treat several diseases and/or conditions characterized by altered/abnormal intracranial compliance, cerebral blood flow and/or intracranial pressure pulsatility/waveform, including hydrocephalus, stroke, dementia and migraine headaches, vasospasms, congestive heart failure, cardiopulmonary bypass or carotid endarterectomy.

A method and system for use in the course of extracorporeal blood flow, e.g., cardiopulmonary bypass, dialysis, and angioplasty procedures, in order to reduce or minimize inflammation, excessive bleeding, and other undesirable side effects. The system can include one or more automated blood parameter sensor modules and one or more blood parameter regulating modules. The system is particularly well suited to monitor and/or regulate blood parameters that include blood analytes (e.g., biomolecules, drugs or metabolites) as well as blood functions (e.g., clotting time, fibrinolytic activity, immune response). The system is particularly well suited for use in the management of clotting (e.g., heparing/protamine) and bleeding (e.g., aprotinin).

A method is disclosed for using fructose-1,6-diphosphate (FDP) to reduce and prevent two very serious problems caused by surgery that requires cardiopulmonary bypass. Before bypass begins, a liquid that contains FDP is intravenously injected into the patient, preferably over a period such as about 10 to 30 minutes, to allow the FDP to permeate in significant quantity into the heart and lungs while the heart is still beating. FDP can be added to the cardioplegia solution that is pumped through the heart to stop the heartbeat, and/or during bypass. This treatment was found to reduce two very important and serious problems that have unavoidably plagued CPB surgery in the past, which are: (1) elevated levels of pulmonary vascular resistance (PVR), which includes pulmonary hypertension; and (2) high occurrence rates for atrial fibrillation. Prior to this discovery, there has never been any satisfactory treatment which could reduce the severity and occurrence rates for these two major problems. FDP also can be co-administered in this manner, along with (1) a buffering or alkalizing agent that counteracts acidosis, such as sodium bicarbonate or THAM, and/or (2) a drug that reduces the formation of lactic acid, such as dichloroacetate.

A treatment apparatus including: a bronchoscope including a flexible shaft having working channel; a transbronchial ablation probe configured to extend from a distal end of the working channel and extend thru a wall of a trachea and into tissue outside of the trachea; and a stabilization element mounted to a distal portion of the flexible shaft, wherein the stabilization element is configured to brace the distal portion against the wall of the trachea while the transbronchial ablation probe is extended through the wall of the trachea.

A system for delivering blood, cardioplegia solution, and other medications or fluids in a pulsatile flow pattern to a patient during cardiopulmonary bypass is disclosed. In a preferred embodiment, a pumping apparatus having at least one chamber is utilized in which a pumping action is achieved by compressing one of the chambers with a piston mechanism, while allowing the other chamber to fill with fluid via retracting its respective piston. The instantaneous flow rate of either of the chambers is determined by the speed of the piston. In a preferred embodiment, a pulsatile flow of fluid is achieved by cyclically alternating the velocity of the piston between two different speeds. A desired average flow rate and/or delivery pressure and/or constant pulse pressure is maintained by adjusting the alternating velocities at the desired frequency and duty cycle. The calculations necessary to obtain a desired average flow rate are performed by a microprocessor, which also controls the movement of the pistons.

The present invention relates to an electro hydraulic-typed blood pulsation pump for the heart cardiopulmonary bypass. The shell of the blood pump is provided with a blood package, which is arranged in the inlet and out blood vessels at the two ends of the blood pump shell. The liquid is pumping in or pumping out of the pump by a piston mechanism, therefore the blood package in the pump can shrink and expand and the blood can pump in and pump out of the blood package. A butterfly-typed valve with single direction is arranged in two ends of his inlet and out blood vessels. The blood can flow in and flow out of the blood package in single direction; therefore the blood supply function of the heart is formed. The circuit, the pulse and the blood flow are controlled by the industrial control computer. By adjusting the rotating speed of the motor, the treatment effect is guaranteed according to the settled moving parameter.

Cerebral and retinal perfusion monitoring devices, systems, and methods, are described. Such devices, systems, and methods can be used during surgical procedures, including cardiac surgery with cardiopulmonary bypass and spine surgery in prone position, to monitor a patient's brain perfusion in real time. In some embodiments, such monitoring allows trends in perfusion over time to be assessed. Such monitoring allows appropriate medical interventions to be undertaken in the event a state of hypoperfusion is detected, thereby reducing risks of brain hypoperfusion and stroke for patients undergoing heart surgery with cardiopulmonary bypass, as well as minimizing risk of retinal artery thrombosis with resulting blindness for patients undergoing prolonged procedures in the prone position.

The invention relates to a cardiopulmonary bypass artificial lung, characterized by leading venous blood in large superficial veins of a human body, conducting in vitro gas exchange in a lung sac cavity consisting of a lung sac cavity, an oxygen intake sac cavity, a diaphragm and capillary bundles, generating arterial blood with supersaturated oxygen content, and transfusing the arterial blood back into the veins for participating in metabolic cycles of the human body. Compared with a physiological gas exchange process of the human body, the artificial lung uses a unidirectional segmented continuous mode to replace a gas exchange mode adopting exhaling and inhaling reciprocating bidirectionally in the same breathing pipeline in an intermittent alternating way, so that the efficiency is higher and the exchange is more thorough. Compared with allopathy in medical care in the prior art which improves the supplied gas quality and increases the amount, the artificial lung changes the inherent defects of body hypoxia situations, is independent and unique, does not rely on a physiological lung to complete gas exchange, and has replacement and compensation functions for treating pulmonary function defects and insufficiencies.

The invention discloses a multi-purpose medical instrument internal structure disinfection machine, which includes a box body, an ozone generator connected with a positive pressure air pump, a negative pressure air pump and a control circuit are arranged in the box body, the ozone generator is connected with the first The negative pressure air pump is connected to the filter through the second conduit, the atomizer is arranged in the box, the atomizer is connected to the first conduit through the third conduit, and the control circuit controls the positive Compression pump, ozone generator, atomizer and negative pressure air pump are opened or closed, and described atomizer is provided with the hydrogen peroxide aqueous solution that volume percent concentration is 8%~12%, and the present invention is applied to various Disinfection of the inside of pipeline medical equipment, such as ventilator, anesthesia machine, lung function tester, extracorporeal circulation machine, artificial kidney dialysis machine, it can completely disinfect the inside of the contaminated instrument without being corroded or damaged.

A maternal-fetal blood group incompatibility immunosorbent therapy apparatus used in the medical field is characterized in that a blood separator and a plasma adsorber are connected through a circulation line to form a cardiopulmonary bypass adsorption device, wherein the blood separator is used for separating blood cells and plasma, as the separated plasma flows through and filters through the plasma adsorber, wherein the pathogenic antibody is adsorbed, the filtered plasma is combined with the separated blood cells and then re-enters a cardiopulmonary bypass adsorption device for circulatingadsorption to achieve the purpose of cleaning the pathogenic antibody, and the plasma adsorber is filled with a solid-phase carrier coated with blood group antigen or anti-blood group antibody with high to low gradient titer from an inlet to an outlet in a layered manner.

A self expanding cannula with improved drainage properties based upon its greater length is provided, along with methods of using the cannula in cardiopulmonary bypass.

The present invention relates to priming solutions used during cardiopulmonary bypass procedures. In particular, the present invention relates to a cardiopulmonary bypass priming solution comprising a balanced salt solution and a combination of oncotic and non-oncotic dextran molecules. The present invention also relates to the use of the priming solution in a cardiopulmonary bypass method, a method of maintaining oncotic pressure in a patient during a cardiopulmonary bypass procedure, and a combination of cardiopulmonary bypass priming solution and cardiopulmonary bypass apparatus.