35 results about "Alkalizing agent" patented technology

The present invention relates to a pharmaceutical composition for oral administration comprising a GLP receptor agonist or a pharmaceutically acceptable salt or derivative thereof, one or more penetration enhancers, one or more mucous membrane adhesives, and one or more basifying agents. More preferably, the penetration enhancer is a penetration enhancer based on medium chain fatty acids.

The invention discloses a soybean protein adhesive film and a preparation method thereof. The soybean protein adhesive film is prepared from the following raw materials: 6 parts of soybean protein, 0.1-1 part of an alkalizer, 0.5-5 parts of a protein denaturant, 1.2-2.4 parts of a polyol plasticizer and 30-60 parts of a solvent. The preparation method comprises the following steps: S1, dispersing soybean protein in a solvent to form a suspension, adding an alkalizer and a protein denaturant to obtain a mixed solution A, and heating and stirring for protein denaturation treatment to obtain a denatured soybean protein solution; s2, adding a polyol plasticizer into the modified soybean protein solution, and uniformly mixing to obtain a film forming solution; s3, coating a substrate with the film forming liquid to form a wet film; and S4, drying the wet film to obtain the soybean protein glue film. By reasonably using the basifier, the protein denaturant and the plasticizer, the solid content of the soybean protein adhesive film is improved, so that the prepared soybean protein adhesive film exists in a solid adhesive film form, the amount of water needing to be evaporated in the hot pressing process is reduced, and the problem that the solid content of traditional liquid soybean meal adhesive is low is thoroughly solved.

Methods for treating fibromyalgia and one or more of its associated symptoms of pain, sleep disturbance and / or fatigue comprising administering to a subject in need thereof, 5.6 mg cyclobenzaprine HCl per day in one or more dosage units by transmucosal administration, the cyclobenzaprine HCl being in a form of a eutectic, and the one or more dosage units further comprising a basifying agent.

Disclosed are novel phenalene-l-one photosensitizers capable of generating singlet oxygen, compositions comprising at least one novel phenalene-l-one photosensitizer, and uses of the novel phenalene-l-one photosensitizers. The compositions are bleaching compositions, comprising at least one phenalene-l-one photosensitizer, at least one persulfate, at least one alkalizing agent and at least one peroxide source. (Formula I)

The invention relates to a solid water-dispersible pharmaceutical composition for use in the treatment of a disease, said treatment comprising dispersing said pharmaceutical composition into an aqueous liquid to produce an enteraliy administrable liquid containing at least 0.5 gram of said pharmaceutical composition and at least 0.3 g / 1 of edaravone, followed by enteral administration of said enteraliy administrable liquid to a human patient in an amount to provide a dose of 30-300 mg of edaravone, said pharmaceutical composition comprising: 2-50 weight % of 3-methyl-l-phenyl-2-pyrazolin-5-one (edaravone); and 3-50 weight % of a water-soluble alkalizing agent. This solid composition containing edaravone can be easily dispersed in an aqueous liquid to prepare an aqueous solution of edaravone that can be ingested by a patient. The solid composition of the invention provides the advantage that when the composition is introduced into water the edaravone dissolves very rapidly and the enteraliy administrable liquid thus obtained has a high oral bioavailability.

The present invention relates to a bleaching and / or lightening composition A for keratin fibres, preferably human keratin fibres, more preferably human hair, comprising: a) tris (hydroxymethyl) aminomethane and / or 2-amino-2-methyl-1, 3-propanediol, and / or salts thereof, and / or mixtures thereof; b) one or more inorganic basifying agents, c) one or more ammonium salts or alkali metal salts or alkaline earth metal salts of peroxysulfates or peroxysulfates.

The present invention relates to a bleaching and coloring composition for keratin fibers, preferably for human keratin fibers, more preferably for human hair, comprising one or more alkalizing agents, one or more bleaching compounds, HC Blue 18 and / or its salts, tetrabromophenol blue and / or its salts.

The presently claimed invention relates to hair colouring formulations comprising 2-amino-1-Propanol (2A1P / Alanilol) as an alkalizing agent. The compositions of the presently claimed invention provide a series of desirable properties to the user such as a pleasant low chemical odour and a high level of hair bleaching with an acceptable damage profile. The compositions of the presently claimed invention further enable formulators to deliver a wider range of shades or colour formulations by reducing the off-toning adducts of oxidative dyes.

Compositions and Processes for Modifying Hair Color: The disclosure relates to compositions for modifying the color of keratin fibers and processes for using the compositions. The compositions include (a) a bonding system comprising (i) at least one first bonding agent selected from alpha-hydroxy acids comprising at least three hydrogen-donating carboxyl groups and / or their salts; (ii) at least one second bonding agent selected from glycine and / or its salts; and (iii) optionally, at least one third bonding agent selected from aminosulfonic acids and / or their salts; (b) at least one fatty alcohol; (c) at least one fatty acid; (d) at least one alkyl polyglucoside; (e) at least one alkalizing agent; and (f) at least one solvent. The compositions may further comprise one or more oxidation dyes, couplers, oxidizing agents, or combinations thereof. Figure: None

The present invention relates to a liquid composition for capsule filling containing acetylcysteine ​​and a soft capsule formulation containing the same. The liquid composition for capsule filling according to the present invention comprises acetylcysteine, polyethylene glycol having an average molecular weight of 300 to 600, and an alkalizing agent. The liquid composition for capsule filling according to the present invention can be used as a filler for soft capsule formulations and can improve the storage stability of acetylcysteine ​​even in the form of a liquid composition. In addition, the soft capsule formulation according to the present invention can exhibit dissolution characteristics of acetylcysteine ​​under various pH conditions.

The invention discloses a method for treating dirt deposition on the secondary side of a steam generator of a nuclear power plant, which comprises the following steps of: filtering and measuring the content of corrosion products in each water supply system of the nuclear power plant by adopting a sampling device with the filtering precision less than or equal to 0.4 mu m; each water supply system of the nuclear power plant comprises a steam drainage system, a condensation water system and a main water supply system. Adding a mixed alkalizer of ethanolamine and ammonia into the steam drainage system to increase the pH value of the steam drainage system; and adding a polyacrylic acid dispersing agent into the main water supply system. By applying the secondary side dirt deposition treatment method for the nuclear power plant steam generator, secondary side dirt deposition of the nuclear power plant steam generator can be effectively reduced. Effective reduction of dirt deposition on the secondary side of the steam generator of the nuclear power plant not only facilitates prolonging of the service life of steam generator equipment, but also is the key of prolonging of the service life of the steam generator from 40 years to 60 years, and unnecessary maintenance and labor cost and overhaul period of a nuclear power unit can be saved.

Compositions and Methods for Modifying Hair Color: This disclosure relates to compositions for modifying the color of keratin fibers and methods for using the compositions. The compositions include (a) a bonding system comprising (i) at least one first bonding agent selected from citric acid and / or salts thereof, and (ii) at least one second bonding agent selected from amino acids, aminosulfonic acids, salts thereof, or combinations thereof; (b) at least one fatty alcohol; (c) at least one fatty acid; (d) at least one alkyl polyglucoside; (e) at least one alkalizing agent; and (f) at least one solvent. The compositions may further include one or more oxidizing dyes, couplers, oxidizing agents, or combinations thereof. Figure for abstract: 1

The present disclosure relates to a solid oral pharmaceutical composition comprising a therapeutically effective amount of pitavastatin or a pharmaceutically acceptable salt, an alkalizing agent and colloidal silicon dioxide. Furthermore, the present disclosure also relates to said composition further comprising a therapeutically effective amount of Ezetimibe.

A single-agent air-oxidative hair coloring product according to an aspect of the present disclosure contains (A) gallic acid or a derivative thereof, (B) an alkalizing agent, and (C) an oxidative dye. A method for producing a single-agent air-oxidative hair coloring product containing a plurality of components including (A) gallic acid or a derivative thereof, (B) an alkalizing agent, and (C) an oxidative dye according to another aspect of the present disclosure comprises: adding component (A) to a stirring tank and stirring; adding component (B) to the stirring tank and stirring; and adding component (C) to the stirring tank and stirring. In another aspect of the present disclosure, component (A) is added to the stirring tank and stirred before component (B) is added to the stirring tank or after component (B) is added to the stirring tank and stirred.

This disclosure is also based on the discovery that it is possible to eliminate the sweetener from a fexofenadine zwitterion dihydrate suspension and still achieve satisfactory taste masking by including the sweetener solely in the external phase. In addition, this disclosure is based on the discovery that it is possible to use an inert matrix containing only mannitol when turning suspensions of fexofenadine zwitterion dihydrate into granules. Accordingly, this disclosure is directed to sugar-free chewable fexofenadine tablets comprising sprayed and dried fexofenadine granules comprising a mannitol matrix and a composition devoid of a sweetener, said composition comprising fexofenadine zwitterion dihydrate, a wetting agent, a binder, an alkalizing agent, and a buffer; and an external phase comprising a flavoring agent, a disintegrant, the wetting agent, a diluent, a sweetener, and one or more lubricant. The disclosure also includes methods of making these tablets. In one embodiment, the method of producing a sugar- free chewable fexofenadine tablet includes: generating fexofenadine granules by spraying and drying a liquid fexofenadine suspension devoid of a sweetener comprising fexofenadine zwitterion dihydrate, a wetting agent, a binder, an alkalizing agent, and a buffer onto a mannitol matrix; and compressing the fexofenadine granules with an external phase comprising a flavoring agent, a disintegrant, the wetting agent, a diluent, a sweetener, one or more lubricant.

This invention discloses a method for preparing organothioether compounds, using thiophenol compounds and olefins as raw materials, and reacting them with an alkalizing agent and a catalyst in a solvent under blue light irradiation at room temperature. The method involves using a tert-butanol salt to abstract a hydrogen atom at the S-position of R-thiophenol, generating an R-thiophenol anion. Under light irradiation, the R-thiophenol anion loses electrons to generate an R-thiophenol free radical. The R-thiophenol free radical then passes through Fe... 3+ The method involves catalytic reaction with olefins to yield organosulfur ethers. This well-designed method does not rely on halogens, is relatively reactor- and environmentally friendly, achieves a yield of up to 65%, and is cost-effective. It provides a novel approach for the synthesis of organosulfur ethers and shows promise for industrial applications.

The invention relates to the technical field of capsule preparation, and discloses a high-stability isavuconazole sulfate capsule and a preparation method thereof.The preparation method comprises the following steps that S1, isavuconazole sulfate, a polymer carrier, a disintegrating agent and a surfactant are dissolved in an organic solvent to obtain an organic phase, and a water-soluble stabilizer is dissolved in purified water to obtain a water phase; s2, dropwise adding the organic phase into the water phase by using an injection pump while stirring, continuously stirring after dropwise adding to form primary emulsion, homogenizing the primary emulsion, adding a spray drying protective agent, stirring for dissolving, performing spray drying, performing cyclone separation, collecting powder, and drying until the water content is less than or equal to 3.0 to obtain a pretreated prodrug; and S3, mixing the pretreated prodrug, a filler, an alkalizer and a lubricant, and filling a capsule shell with the mixture to obtain the capsule. The isavuconazole sulfate capsule prepared by the invention has high drug loading capacity, excellent in-vitro dissolution performance and outstanding long-term chemical and physical stability, and provides a high-quality oral preparation choice for clinic.

Disclosed are novel phenalene-1-one photosensitizers capable of generating singlet oxygen, compositions comprising at least one novel phenalene-1-one photosensitizer, and uses of the novel phenalene-1-one photosensitizers. The compositions are bleaching compositions, comprising at least one phenalene-1-one photosensitizer, at least one persulfate, at least one alkalizing agent and at least one peroxide source.

An antibacterial catheter and a preparation method therefor, and an external drainage device. The antibacterial catheter (1) comprises a catheter main body, wherein the materials of the catheter main body comprise silica gel. A solvent used during the preparation process of the antibacterial catheter (1) comprises hexafluoroisopropanol. The catheter main body is swelled by means of using the solvent, such that the antibacterial agent is dispersed inside the catheter main body. The catheter main body of the antibacterial catheter (1) is swollen by means of the solvent, and the solvent used contains hexafluoroisopropanol. Hexafluoroisopropanol has a good swelling effect on a catheter main body containing silica gel, and does not require the addition of an additional alkalizing agent, penetrant or drug solubilizer, or the use of subsequent treatments, such as heating or autoclaving. The external drainage device (4) can be connected to the antibacterial catheter (1). By means of the outer drainage device (4), it is convenient to adjust the height of a drainage drip bottle (300), and the accuracy and convenience of the reading of the drainage drip bottle (300) is improved; and it is convenient fix a liquid collection bag. In addition, the structure of the outer drainage device (4) is simple.

The present invention is directed to embodiments of a method for coloring hair using an oxidative hair coloring composition based upon the primary dye compounds MBB, Aminol and optional secondary precursor and coupler compounds PAP, DPE, MAP, AHT and EOAP, a carbonate and / or bicarbonate source, an alkalizer and one or more amino acids. Additional subsidiary precursors and couplers may be included to broaden the color space delivered by the primary dye compounds. The oxidative hair coloring composition is free of resorcinol and C1-C10 alkyl resorcinol. The L*a*b* color space of embodiments of the oxidative hair coloring composition as measured by L*a*b* techniques is about the same as that delivered by the resorcinol based composition.

To provide sheet-like processed food materials having a meat-like texture such as chicken skin, and a method for manufacturing the same.SOLUTION: Sheet-like processed food materials having a meat-like texture such as chicken skin are obtained by mixing at least one type selected from plant protein materials and dietary fiber materials with at least plant-based milk, konjac raw material, an alkalizing agent, and water to obtain a raw material mixture, forming the raw material mixture into sheet-like shapes, and heating and solidifying them.SELECTED DRAWING: Figure 1

The present disclosure relates to hair dye cartridges and compositions for use in hair dye cartridges. The present disclosure relates to hair dye base compositions and color developer compositions that can be incorporated into hair dye cartridges, combining these compositions and dispensing them onto the hair. The hair dyeing box comprises (a) one or more hair dyeing color base compositions; and (b) one or more developer compositions that can combine to form an active hair dye composition and dispense onto the hair. The hair dye base compositions generally comprise one or more oxidation dye precursors; one or more basifying agents; one or more reducing agents; optionally, one or more cationic conditioning polymers; one or more surfactants; one or more water soluble solvents; and water. The developer compositions typically comprise one or more oxidizing agents; one or more surfactants; and water. The unique components and fluid characteristics of the various compositions allow devices or appliances comprising them to combine and dispense a hair color base composition with a developer composition in a predetermined ratio precisely with excellent consistency for application to the hair.

Disclosed are novel phenalene-1-one photosensitizers capable of generating singlet oxygen, compositions comprising at least one novel phenalene-1-one photosensitizer, and uses of the novel phenalene-1-one photosensitizers. The compositions are bleaching compositions, comprising at least one phenalene-1-one photosensitizer, at least one persulfate, at least one alkalizing agent and at least one peroxide source.

The invention relates to agents for oxidative hair dyeing, containing, in each case based on the weight of the agent, 78-95 wt.%, preferably 82-91 wt.%, water, at least one oxidation dye precursor, at least one alkalizing agent, at least one non-ionic surfactant in a total amount of 0.1-3 wt.%, preferably 0.3-2.5 wt.%, and particularly preferably 0.8-2 wt.%, a thickener system containing cellulose fibers and at least one further thickener from the group of polysaccharides and modified polysaccharides and mixtures thereof, wherein no saturated and unsaturated non-alkoxylated alkanols having a hydroxy group and 1 to 50 carbon atoms in the alk(en)yl group and no saturated and unsaturated alkane carboxylic acids having 1 to 50 carbon atoms and no oxidizing agents are contained; the invention also relates to a packaging unit containing this agent, and to methods using this agent.

The present invention relates to a pharmaceutical composition for oral administration comprising a GLP receptor agonist or a pharmaceutically acceptable salt or derivative thereof, one or more medium-chain fatty acid-based penetration enhancer comprising an aromatic functional group, and one or more medium-chain fatty acid-based penetration enhancer not comprising an aromatic functional group. The pharmaceutical composition may also optionally include an alkalizing agent.

The application discloses a chemical cleaning corrosion inhibitor desorption agent and belongs to the technical field of chemical cleaning. The desorption agent is composed of 15-25% alkalizer, 0.1-1.0% solubilizer and desalted water. The corrosion inhibitor used in the chemical cleaning process is adsorbed on the metal surface and is difficult to be washed out of the system by water. During the start and operation of the unit, the corrosion inhibitor is gradually desorbed and decomposed, which leads to the problems of over-standard water vapor hydrogen conductivity, unqualified water quality for a long time and the like. After the chemical cleaning is completed, the desorption agent is added during the water washing work, so that the desorption of the corrosion inhibitor is promoted, the corrosion inhibitor is taken out of the system with the water washing, and the problems of over-standard unit water vapor hydrogen conductivity caused by the adsorption of the corrosion inhibitor are solved.

The present disclosure relates to a solid oral pharmaceutical composition comprising a therapeutically effective amount of pitavastatin or a pharmaceutically acceptable salt, an alkalizing agent and colloidal silicon dioxide. Furthermore, the present disclosure also relates to said composition further comprising a therapeutically effective amount of Ezetimibe.

A tannery product designed to be introduced into a bath for oxidative hair removal treatment of animal hides and skins includes a perhydrate compound, an alkalizing agent and an activating agent. The treatment bath can be used in a method for oxidative hair removal of animal hides and skins. The method includes introducing the activating agent into the bath in a proportion to the weight of the hide and skin to be treated between 0.0001 and 0.01.

This invention discloses a modified polyaluminum sulfate quick-setting agent, its preparation method, and its application. The agent comprises the following raw materials in parts by weight: 20-60 parts aluminum sulfate, 1-6 parts solid alkalizing agent, and 30-70 parts modified polyacrylamide. The preparation process of the modified polyacrylamide includes the following steps: 2-(2,4-dihydroxyphenyl)-2H-benzotriazole is dissolved in anhydrous ethanol solution and mixed with a 0.1% (w / w) Na2CO3 aqueous solution under nitrogen protection. Then, 1,2,7,8-diepoxyoctane is added, and the reaction is carried out at 80°C for 7 hours to obtain intermediate 1. Intermediate 1 is mixed with (1,3-dimethylbutyl)-N'-phenyl-p-phenylenediamine and reacted to obtain intermediate 2. A polyacrylamide solution is added to intermediate 2, and the reaction is carried out to obtain modified polyacrylamide. This invention effectively improves the antioxidant and UV-resistant capabilities of the modified polyaluminum sulfate quick-setting agent, thus extending its service life.

The present invention is directed to an oxidative dyeing composition A for keratin fibers, preferably for human keratin fibers, more preferably for human hair, comprising a) one or more oxidative hair dye(s), b) one or more inorganic pigment(s), c) one or more alkalizing agent(s), wherein the weight ratio of one or more compound(s) according to group b) to compound(s) according to group a) is 1 or more.