94 results about "Thiophenol" patented technology

The invention is applied to the technical field of compound preparation, and discloses a synthesis method of o-aminothiophenol, which comprises the following steps: uniformly mixing 2-chloronitrobenzene, water and strongly basic anion exchange resin, heating, dropwise adding a hydrosulfide aqueous solution, carrying out heat preservation reaction, cooling and filtering after the reaction is finished, and drying to obtain the o-aminothiophenol. Eluting the filter cake with liquid alkali, acidifying and layering to obtain an o-aminothiophenol crude product, and distilling to obtain the product. The thiophenol and the basic group of the resin are salified, the main reaction for generating 2-nitrothiophenol is promoted in the early stage, and the generation of a nitroreduction byproduct 2-aminochlorobenzene is greatly reduced, so that the product yield is greatly improved; the product stability is improved by salifying, so that disulfides are prevented from being formed by bimolecular oxidation of thiophenol, reduction is not needed, the product can be obtained by acidification after alkali elution, the process is shortened, and the cost is reduced; the production process is simple to operate, pressure reaction is avoided, the requirement on equipment is low, and the yield is high and can reach 95% or above; the purity of the obtained product can reach 99% or above.

The application discloses a preparation method of perfluoroalkyl aryl sulfide, and a structural formula of the perfluoroalkyl aryl sulfide is shown as formula (I); the method comprises the following steps: firstly, obtaining corresponding aryl sulphenyl chloride by chlorination of thiophenol; under the condition that fluoride and crown ether exist, obtaining perfluoro-1,1-dimethylbutyl negative ion by addition of D-2 ‑ And the aryl sulphenyl chloride added is subjected to a nucleophilic substitution reaction to synthesize a product (1,1,1,3,3,4,4,5,5,5-decafluoro-2-trifluoromethylpent-2-yl)(aryl)sulfide. The application adopts a reaction strategy of efficient coupling of thiophenol and perfluoroalkyl, and can be used for preparing various fluorine-containing benzene sulfide compounds.

The application discloses a preparation method of a key intermediate of dapagliflozin, and belongs to the technical field of preparation of medical intermediates. The preparation method of the key intermediate of dapagliflozin comprises the following steps: 1, 1-ethoxy-4-methylbenzene is prepared by using p-cresol, sodium hydroxide and diethyl sulfate; 2, (4-ethoxybenzyl) phenyl sulfide is prepared by using 1-ethoxy-4-methylbenzene, thiophenol, a palladium catalyst, an alkali and an oxidant; 3, 1-benzyl-4-ethoxybenzene is prepared by using (4-ethoxybenzyl) phenyl sulfide under a hydrogen atmosphere; 4, 4-ethoxy-2'-chlorobenzhydrol is prepared by carrying out chlorination reaction on 1-benzyl-4-ethoxybenzene; and 5, 5-bromo-2-chloro-4'-ethoxybenzhydrol is prepared by carrying out bromination reaction on 4-ethoxy-2'-chlorobenzhydrol. The yield and purity of 5-bromo-2-chloro-4'-ethoxybenzhydrol prepared by the method are higher, the process is safer, and the production cost is reduced.

The invention discloses a preparation method of an Elobixibat intermediate 2, 4-dibromo-5-methoxybenzene sulfonyl chloride (I), and belongs to the field of preparation of drug intermediates. The method comprises the following steps: oxidizing 3-methoxythiophenol serving as a raw material with hydrogen peroxide to generate a compound II, halogenating the compound II with bromine to generate a compound III, and finally oxidizing and chlorinating with zirconium chloride and hydrogen peroxide to generate the compound 2, 4-dibromo-5-methoxybenzenesulfonyl chloride (I). The preparation method of the intermediate compound III has the advantages of stable property, high yield, high purity, good product appearance, simple post-treatment, suitability for industrial production and the like.

This invention provides a polynuclear metal cluster based on salicylaldehyde acetal-2-thiophenol ligand, its preparation method, and its application. The chemical formula of the polynuclear metal cluster is Co4(C 13 H9NOS)6·2CH3CN·CH3OH, where C 13 H9NOS is salicylaldehyde acetal-2-thiophenol, with Co forming a six-coordinate octahedral configuration with N, O, and S. The salicylaldehyde acetal-2-thiophenol ligand in the polynuclear metal cluster of this invention can effectively stabilize the active center of metallic cobalt, resulting in a polynuclear metal cluster with significant OER activity and broad prospects for practical applications.

The invention discloses a method for efficiently preparing benzo [e] [1, 2, 3] oxathiazide 2, 2-dioxide derivatives with various structures by catalyzing aromatic benzo [e] [1, 2, 3] oxathiazide 2, 2-dioxide and NHC catalytic oxidation cross dehydrogenation coupling of amine, alcohol, phenol, thiol and thiophenol through carbene, and is characterized in that benzo [e] [1, 2, 3] oxathiazide 2, 2-dioxide, a nucleophilic reagent, a carbene catalyst and alkali are used as raw materials for preparing the benzo [e] [1, 2, 3] oxathiazide 2, 2-dioxide derivatives with various structures. The preparation method comprises the following steps: putting benzo [e] [1, 2, 3] oxathiazide 2, 2-dioxide as a raw material, an oxidant and a solvent in an air atmosphere, reacting at room temperature or under a heating condition, removing the solvent in vacuum to obtain a coarse material, and performing silica gel column chromatography purification on the coarse material to obtain the target compound benzo [e] [1, 2, 3] oxathiazide 2, 2-dioxide derivative. The reaction is carried out under extremely mild conditions, the substrate range is wide, and the tolerance of functional groups is good. In addition, the biological activity research of the target compound shows that the compound has the potential of being developed into an effective antifungal agent for crop protection. The compound can be used as a potential candidate drug for inhibiting phytopathogen fungi, and has good research and development value.

The present application relates to the fine chemical technology field, specifically to a kind of preparation of bis (4-tolyl sulfenyl) di-deuteromethane method.The domestic research and synthesis of bis (4-tolyl sulfenyl) di-deuteromethane are less reported, only a few foreign literatures provide corresponding preparation method.Aiming at the above problems, the present application provides a kind of preparation of bis (4-tolyl sulfenyl) di-deuteromethane method, the present application is reacted by 4-methyl phenyl sulfenol and 1-(chloro di-deuteromethyl)-1,4-diazabicyclo [2.2.2] octane-1-ammonium chloride in the acetonitrile solution containing HI, bis (4-tolyl sulfenyl) di-deuteromethane is successfully prepared, the synthetic route of the present application is simple and efficient, raw material is easy to obtain, and has good commercial value.

The application belongs to the technical field of biological medicine, and discloses a synthesis method of aryl F-18 labeled sulfuryl chloride and application of the aryl F-18 labeled sulfuryl chloride in amine compound labeling. The method takes thiophenol derivative as a labeling precursor, obtains F-18 labeled thiophenol intermediate through photocatalytic aryl F-18 fluorination reaction, and then obtains aryl F-18 labeled sulfuryl chloride through N-chlorosuccinimide oxidation chlorination. The obtained aryl F-18 labeled sulfuryl chloride (4-[ 18 F] fluorobenzenesulfonyl chloride) can occur sulfurylization reaction with various amine compounds at room temperature, and the radiochemical conversion rate is as high as 98%. The application is successfully applied to novel synthesis of AMPA receptor PET imaging agent[ 18 F]2 (the conversion rate is 96%, which is much higher than 13% reported in the literature). The application has the advantages of mild reaction condition, high conversion rate and wide substrate application range, and provides an efficient method for innovative preparation of F-18 labeled PET probes.

The invention relates to the field of rubber materials, and particularly discloses a golf ball inner core material, a preparation method thereof and a high-elasticity golf ball. The invention discloses an inner core material of a golf ball. The inner core material comprises the following raw materials in parts by weight: 100 parts of butadiene rubber, 25-30 parts of zinc acrylate, 0.5-1.5 parts of a vulcanizing agent, 4-8 parts of zinc stearate, 0.4-0.8 part of pentachlorothiophenol, 4-8 parts of zinc oxide and 15-20 parts of filler. The golf ball inner core material has the advantages of being good in rebound resilience and good in hitting resistance, the service life can be prolonged, and a better ball hitting feeling can be brought.

The invention discloses a thiophenol-heptamethine cyanine dye derivative as well as self-assembled nanoparticles, a preparation method and application thereof. The derivative is a thiophenol-heptamethine cyanine dye monomer derivative or a 1, 3, 5-benzene trithiophenol-heptamethine cyanine dye triad derivative; the thiophenol or the 1, 3, 5-benzene trithiophenol is connected with a meso-carbon atom of the heptamethine cyanine dye through a sulfur atom, and the heptamethine cyanine dye is formed by connecting two nitrogen-containing heterocyclic ring units through a conjugated methine chain; the nanoparticles are obtained by dropwise adding a derivative solution into water and then removing an organic solvent. The synthesis method of the thiophenol-cyanine dye derivative is simple and easy to implement, stable nanoparticles can be formed, the tumor targeting property can be improved, the aggregation effect far better than that driven by traditional weak interaction is achieved, synchronous optimization of high tumor accumulation and extremely high heat production efficiency is successfully achieved through self-assembly of nanoparticles, and the thiophenol-cyanine dye derivative has good application prospects. An innovative strategy is provided for the development of a high-performance tumor photo-thermal reagent.

The invention discloses an efficient and simple synthesis method of a dibenzotetrathiafulvalene derivative, which is characterized in that benzene-1, 2-thiophenol or a derivative of benzene-1, 2-thiophenol is subjected to dimerization in a solvent containing acetic acid under a solvothermal reaction condition to obtain the dibenzotetrathiafulvalene or the derivative of dibenzotetrathiafulvalene. The solvothermal reaction conditions are mild, the operation is simple, and the method is suitable for large-scale preparation and environment-friendly. No toxic by-product is generated in the reaction, the reaction product does not need to be purified, the high-purity crystal compound can be obtained, the product efficiency is improved, and the selectivity is guaranteed.

The invention discloses a green light-emitting diode device and a preparation method thereof. FAPbBr3 perovskite nanocrystals are synthesized by a ligand-assisted reprecipitation method, wherein FABr and PbBr2 serve as FA sources, Pb sources, and Br sources, chloroform serves as an antisolvent, and acetonitrile serves as a reaction quencher. The green light-emitting diode device comprises a substrate printed with an anode, a hole transport layer, a hole injection layer, a light-emitting layer, a first electron transport layer, a second electron transport layer, and a cathode, which are arranged in sequence from bottom to top. By adding thiophenol as a new organic ligand to acetonitrile to replace part of the traditional ligand, the surface defects of the material are significantly passivated, thereby improving the photoluminescence quantum yield of the material and the photoelectric performance of the LED prepared from the material. Unlike traditional ligands, thiophenol does not contain a long alkyl chain but has a benzene ring with better conductivity, so the electrical performance of the LED prepared using the thiophenol is also improved. In addition, it can be proved that the introduction of thiophenol does not affect the emission wavelength of the LED.

The invention relates to the technical field of tire rubber manufacturing, and discloses an electric vehicle tire tread rubber composition containing a thiophenol lignin hybrid material and a mixing method of the electric vehicle tire tread rubber composition, and the thiophenol lignin hybrid material is added into the rubber composition. The thiophenol lignin hybrid material is a hydrophobic thiophenol material obtained through reaction modification of lignin and sulfur, can be directly applied to traditional dry-method mixing, effectively improves the dispersity of lignin in rubber, improves the mechanical property and stability of a rubber material, reduces rolling resistance, realizes effective replacement of carbon black, and is simple in process, convenient to operate, convenient, fast and efficient. And large-scale industrial production can be realized more easily.

The invention discloses a hydrophobized thiol-modified silver nanostar paper-based material, a preparation method, and an application thereof, and belongs to the field of perchlorate detection. The method comprises the following steps: first, using NaCl to displace citrate modified on the surface of a silver nanostar sol, and then removing excess chloride ions to obtain the displaced silver nanostar sol; then, using 4-aminothiophenol to perform thiol modification on the displaced silver nanostar sol to obtain the thiol-modified silver nanostar sol; and finally, loading the thiol-modified silver nanostar sol on filter paper by vacuum filtration to obtain a paper-based substrate. The paper-based substrate is then hydrophobized using polydimethylsiloxane to obtain the hydrophobized thiol-modified silver nanostar paper-based material. The method is simple and reliable, and can achieve trace and rapid detection of perchlorate in water by synthesizing an AgNS structure with high plasmon activity, and then performing thiol modification, loading the paper-based substrate, and hydrophobizing the paper-based substrate.

The invention discloses a novel photoinitiator as well as a preparation method and application thereof, a thiophenol group substituted by methyl, ethyl or isopropyl is introduced into a molecular structure of the photoinitiator, so that the absorption wavelength of the photoinitiator is adaptive to a UV-LED light source of 365-405nm, and the problem that the existing photoinitiator is insufficient in matching with the UV-LED light source is solved. The preparation method comprises the following steps: carrying out acylating chlorination on 2, 4, 6-trimethylbenzoyl phenylphosphonic acid through thionyl chloride, condensing the 2, 4, 6-trimethylbenzoyl phenylphosphonic acid and substituted p-thiophenol in an organic solvent, and purifying to obtain a target product, and the preparation process is simple and convenient to operate and suitable for industrial production. The obtained photoinitiator shows good compatibility and efficient curing efficiency in a UV-LED photocuring system, can be widely applied to the fields of printing ink, photocureable coatings, UV adhesives and the like, and has important significance in promoting popularization of a UV-LED curing technology.

The application discloses a metal organic complex with controllable morphology and a preparation method thereof, and belongs to the technical field of metal organic complex preparation. The preparation method of the metal organic complex with controllable morphology comprises the following steps: dissolving cuprous oxide and 4-hydroxythiophenol in anhydrous ethanol to form a mixed solution A; circulating nitrogen into the mixed solution A and performing air extraction and inflation to obtain a mixed solution B; and performing a heating reaction on the mixed solution B under stirring to obtain a reaction liquid capable of controlling the morphology of the metal organic complex; wherein the morphology of the metal organic complex is controlled by controlling the heating reaction time; and the reaction liquid is sequentially filtered, washed and dried to obtain the metal organic complex, wherein the morphology of the metal organic complex is linear or flaky. According to the method, linear or flaky two completely different morphologies can be stably and controllably obtained by only adjusting the heating reaction time, and the flexibility and convenience of morphology control are remarkably improved.

The invention discloses a preparation method of hydrobromic acid vortioxetine, and belongs to the technical field of organic synthesis. The method comprises the following steps: by taking o-aminothiophenol and Boc2O as initial raw materials, carrying out amino protection to obtain an intermediate 1; reacting the intermediate 1 with 2, 4-dimethyl bromobenzene under an alkaline condition to form a thioether bond, and acidifying to obtain an intermediate 2; carrying out high-temperature cyclization on the intermediate 2 and bis (2-bromoethyl) amine hydrobromide in mesitylene, so as to obtain a crude product of the hydrobromic acid vortioxetine; and recrystallizing the crude product with 95% ethanol to obtain a high-purity final product. The route is simple, only three-step reaction is needed, a noble metal catalyst is not needed in the whole process, and the problem of metal residues is fundamentally avoided; the selected raw materials are easy to obtain, the reaction condition is mild, the operation is simple and convenient, the process is stable, the total yield is good, the product purity is as high as 99.9%, and the method is suitable for large-scale production.

The application discloses an aggregation-induced emission material with high fluorescence quantum yield and large stokes shift, a preparation method and application thereof, and belongs to the technical field of preparation of the aggregation-induced emission material. The preparation method comprises the following steps: obtaining an intermediate by means of Suzuki-Miyaura coupling reaction of an organic boric acid and bromosalicylaldehyde; and adding the intermediate, sodium metabisulfite and aminophenylthiophenol into an organic solvent, and then performing high-temperature reaction to prepare the aggregation-induced emission material. The aggregation-induced emission material is synthesized by means of a two-step method, can be rapidly and mass-produced, and has the advantages of high fluorescence efficiency, large stokes shift, good stability and the like.

The present application relates to the determination of pentachlorothiophenol in rubber, comprising the following steps: (1) pyrolysis gas chromatography mass spectrometry test standard solution; (2) draw standard curve; (3) sample test; (4) sample qualitative judgment; (5) sample quantitative calculation result. The present application optimizes the quantitative method of pyrolysis-gas chromatography-mass spectrometry (Py-GC-MS) for detecting the content of pentachlorothiophenol in rubber products, and quickly confirms the content of pentachlorothiophenol in rubber products.

This invention discloses a method for preparing co-assembled nanoparticles of thiophenol-heptamethine dye monomer and its triplet derivative, as well as their applications. The co-assembled nanoparticles comprise thiophenol-heptamethine dye monomer and a triplet derivative. The derivative is formed by linking the sulfur atom of thiophenol to the middle carbon atom of heptamethine dye, and the heptamethine dye is formed by two nitrogen-containing heterocyclic units linked by a conjugated methylene chain. The method involves mixing solutions of the two derivatives and adding them dropwise to water, followed by removal of the organic solvent to obtain co-assembled nanoparticles with uniform particle size. This invention significantly enhances the assembly stability of the nanoparticles while successfully retaining the excellent photothermal conversion efficiency of the triplet derivative, overcoming the technical bottleneck of the difficulty in stabilizing high-heat-generating molecules into particles. It achieves synergistic optimization of the assembly stability and photothermal efficiency of photothermal reagents, providing a novel design strategy and technical support for the development of high-performance tumor photothermal therapy drugs.

This invention discloses an internal standard-assisted petal-shaped SERS nanoprobe, its preparation method, and its applications. The internal standard-assisted petal-shaped SERS nanoprobe of this invention is a core-molecule-shell structure gold nanoprobe consisting of a gold nanosphere core, an internal standard modifying molecule, a petal-shaped gold nanoshell, and a recognition molecule, 4-nitrobenzenethiophenol. The internal standard modifying molecule is a Raman signal molecule with nitrile, alkyne, or azide functional groups. This invention uses a Raman signal molecule as an internal standard modifying molecule to modify the gold nanosphere core. The corrected working curve exhibits good reproducibility and small error, improving the reliability of the detection results. Growing a petal-shaped gold nanoshell on the molecular layer of the internal standard modifying molecule enhances the SERS activity both inside and outside the SERS substrate, and the petal-shaped shell increases the surface area of ​​the SERS substrate. Furthermore, the recognition molecule of this invention enables ratiometric Raman detection of hydrogen sulfide, effectively reducing background signal interference and improving detection sensitivity.

The invention discloses a synthesis method of diaryl methyl sulfide under a biological compatibility condition, which comprises the following steps: adding a p-methylene benzoquinone derivative and a thiophenol thiol derivative into a reaction solvent, stirring and reacting for 4 hours at room temperature to obtain a reaction solution, filtering and removing the reaction solvent of the reaction solution to obtain diaryl methyl sulfide. And purifying by thin layer chromatography / column chromatography to obtain the diaryl methyl thioether compound. The p-methylene benzoquinone derivative used in the method is easy to synthesize, high in conversion rate and wide in applicable substrate range, and in addition, the method is simple in step, convenient to operate and high in product yield, does not use any metal compound, and has the advantages of being high in atom economy and environmentally friendly.

This invention belongs to the field of electrocatalytic materials technology, and relates to a nitrogen-sulfur co-doped mesoporous carbon catalyst, its preparation method, and its application. The catalyst is a nitrogen-sulfur co-doped carbon-based material, obtained by self-assembly and high-temperature carbonization using F127 as a template agent and m-aminothiophenol as a precursor. The catalyst possesses abundant active sites, optimized electronic structure, and mesoporous morphology, exhibiting high activity, high selectivity, and excellent stability in the electrocatalytic oxygen reduction reaction, making it suitable for efficient and environmentally friendly electrosynthesis of hydrogen peroxide.

The application discloses a reactive phosphate functional emulsifier and a preparation method thereof, relates to the technical field of emulsifiers, and comprises the following steps: mixing vinyl salicylaldehyde, ethyl acetate and triethylamine, stirring under an inert atmosphere, adding phenyl phosphorodichloridate in an ice bath, centrifuging, washing and drying after warming reaction to obtain a preform; ultrasonically mixing the preform with anhydrous ethanol, adding hyperbranched polyether amine, continuously ultrasonically mixing, then adding 2-amino-4-fluorothiophenol for constant-temperature reaction, washing and drying after removing the solvent to obtain a mixture; stirring the mixture with anhydrous ethanol and an initiator, high-speed dispersing cyclic siloxane, adding glycidyl methacrylate for heating reaction, washing and drying after gradient cooling and solidification to obtain the emulsifier; by introducing cyclic siloxane and hyperbranched polyether amine, a hydrophobic film and a hydrogen bond network hierarchical protection system are constructed, the hydrolysis resistance and the flame resistance of the emulsifier are improved, and the stability of water-based paint is improved.

This invention relates to a method for preparing and applying an ordered silver nanoparticle@bismuth nanosheet@copper mesh array. First, bismuth nanosheets are grown on the surface of a copper mesh through an etching reaction using an immersion method. Then, silver nanoparticles are sputtered onto the surface of the bismuth nanosheets, resulting in an ordered silver nanoparticle@bismuth nanosheet@copper mesh array film. This array film is then immersed in a 4-p-aminobenzaldehyde (4-ABZ) solution, adsorbing 4-ABZ molecules onto the surface of the silver nanoparticle@bismuth nanosheet@copper mesh array as signal probe molecules. The silver nanoparticle@bismuth nanosheet@copper mesh array with adsorbed 4-ABZ molecules is then placed as a substrate in a packaging environment containing seafood, meat, or other meat-derived foods. The SERS signal intensity of the 4-ABZ molecules on the substrate surface is used to monitor the freshness of the meat-derived foods. As the freshness of the meat-derived foods decreases, the SERS signal of the 4-ABZ molecules on the substrate surface gradually decreases. Meanwhile, the silver nanoparticle@bismuth nanosheet@copper mesh array also exhibits excellent SERS signal response and signal uniformity for organic dye pollutant molecules such as rhodamine 6G and 4-aminobenzylthiophenol (4-ATP), and has important application prospects in the field of environmental monitoring.

The application provides a cheap and simple method for regulating and controlling reduction products of photochemical reactions driven by plasmons at an interface, and belongs to the technical field of catalysis.The application can realize high selectivity and high efficiency of reduction of p-mercaptobenzoic acid (PMBA) molecules adsorbed on silver nanoparticles to generate thiophenol (TP), p-mercaptobenzaldehyde (PMBALD) or p-mercaptobenzyl alcohol (PMBALC) by adjusting excitation of localized surface plasmon resonance (LSPR) and the concentration of silver nitrate.In the method, the generation selectivity of TP, PMBALD or PMBALC is close to 100% by fine tuning the concentration of silver nitrate, and the generation selectivity of PMBALD or PMBALC is realized by regulating excitation power, excitation wavelength and excitation time of plasmon resonance (LSPR).

The invention relates to the technical field of organic synthesis, in particular to a method for preparing 3H-1, 2-benzodisulfonyl-3-ketone. The invention relates to a conventional synthesis method of 3, 3, 3-H-1, 2-benzodisulfonyl-3-ketone, which needs to use a thiophenol raw material with an unpleasant smell or a transition metal catalyst or a large amount of organic acid. In order to solve the technical problem, the invention provides the method for preparing the 3H-1, 2-benzobenzene-3-ketone, which comprises the following steps: by taking hydriodic acid as an additive and taking 2-methylbenzo [d] isothiazole-3 (2H)-ketone and a sodium sulfide hydrate as reaction raw materials, stirring and reacting in an organic solvent to generate the 3H-1, 2-benzene-3-ketone. In the reaction process, any thiophenol raw material or transition metal catalyst or a large amount of organic acid does not need to be added, the method is simple, raw materials are easy to obtain, and the method is green, environmentally friendly and high in yield and has good application prospects.

The invention relates to the technical field of nanometer material synthesis and catalysis, in particular to a gold nanocluster and a preparation method thereof, a catalyst and a preparation method and application of the catalyst. The molecular formula of the gold nanocluster is Au40 (TBBT) 24 (TPMP); wherein the TBBT is 4-tert-butyl thiophenol, and the TPMP is tri (m-phenyl) phosphine. According to the present invention, the gold nano-particles have the accurate number of atoms and the determined molecular structure, the synergistic effect of the mixed ligands (mercaptan and phosphine) on the surface of the gold atomic nucleus further regulates the electronic structure and the surface property of the cluster, and the adsorption and activation ability of the substrate molecule is optimized so as to improve the catalytic efficiency and the stability; especially for reduction reactions such as reduction of 4-nitrophenol, the cluster can realize efficient catalytic conversion under mild conditions.

This invention relates to a class of compounds containing isopropanolamine substructures, their preparation methods, and applications. These compounds have the structure shown in general formula (I). Based on 4-chlorothiophenol, this invention introduces a nitrogen-containing fragment into this system to synthesize a series of compounds containing isopropanolamine substructures. These compounds exhibit excellent inhibitory effects on plant pathogenic bacteria such as *Bacillus thuringiensis*, *Citrus canker*, *Rhizoctonia solani*, and *Ophiopogon japonicus*.

This invention discloses a fluorescent probe for detecting hypochlorite based on the synergistic effect of ESIPT and AIE in a benzothiazole structure, its preparation method, and its application, belonging to the field of fluorescent probe technology. The invention uses 2-aminobenzylthiophenol and 2-hydroxy-5-methoxybenzaldehyde as starting materials, condensing them to form a benzothiazole derivative as the fluorescent core. A diaminomaleitrile recognition group is introduced through an aldehyde-amine condensation reaction to synthesize the fluorescent probe. After the probe undergoes a specific oxidation reaction with hypochlorite, the C=N double bond breaks, and the ESIPT and AIE effects are synergistically activated, resulting in a significant enhancement of fluorescence. This probe exhibits a fast response, a linear range of 0-200 μM, a detection limit of 29.1 nM, excellent selectivity and anti-interference properties, and stability under pH 6-10 conditions, making it suitable for highly sensitive detection of hypochlorite in aqueous solutions and complex systems.