67 results about "Dinitrobenzene" patented technology

The invention belongs to the technical field of catalyst preparation, and provides an M2 diatomic site catalyst for a reaction for preparing phenylenediamine through dinitrobenzene hydrogenation and a preparation method and application thereof.The catalyst is formed by anchoring transition metal M diatomic sites to the surface of a diamond-graphene carrier and is prepared by taking nano-diamond powder as a raw material through a one-step reaction. Annealing treatment is carried out at the high temperature of 750-850 DEG C, a diamond-graphene carrier of an sp3 atsp2 core-shell structure is constructed, and the surface defect density of the diamond-graphene carrier is regulated and controlled in the process; and depositing metal species on the surface of the carrier through ALD double-step deposition to obtain the M2 diatomic site catalyst with high density and stable structure. The M2 diatomic site catalyst is applied to a reaction for preparing a corresponding phenylenediamine compound through hydrogenation of a dinitrobenzene compound, and high conversion rate and high selectivity can be achieved with low metal loading capacity under mild conditions. The method can be popularized to construction of diatomic catalysts of various transition metals, and has a wide application prospect.

The invention relates to the technical field of preparation of N-(2, 4-dinitrophenyl)-4-nitrobenzoyl aniline, in particular to a method for preparing a nitro amide compound by adopting a microreactor. The method for preparing the nitro amide compound comprises the following steps: introducing a sulfuric acid solution of 4-nitro-N-phenylbenzamide and a nitric acid aqueous solution into a microreactor, and reacting to obtain N-(2, 4-dinitrophenyl)-4-nitrobenzamide; the microreactor is provided with at least two reaction modules which are connected in series, and a sulfuric acid solution of 4-nitro-N-phenylbenzamide is divided into at least two strands which are respectively fed into a first reaction module of the microreactor and other reaction modules except the first reaction module; and the nitric acid aqueous solution enters the microreactor in a way of at least one stream. According to the method, the microreactor is used as a reaction carrier, the temperature in the reaction process is controllable, the raw material conversion rate is increased, and the residual amount of an intermediate N-4-nitro-(4-nitrophenyl) benzamide is reduced.

A curcumin nanococrystal composition including curcumin, a coformer, and a stabilizer. The coformer may include at least one of 3,5-dinitrobenzoicacid, gentisic acid, phloroglucinol, 4,4-bipyridine, tartaric acid, citric acid, and gallic acid. The curcumin nanococrystal composition has a particle size less than 10 nm, and the curcumin has a water-solubility between 5 mg / ml and 20 mg / ml.

The invention relates to a detection method, in particular to a method for detecting aldehyde impurities in polysorbate 20. According to the method, interference caused by the purity of 2, 4-dinitrophenylhydrazine is avoided, derivatization of a reference substance is performed by adopting a method synchronously operating with a test sample, eight aldehyde ketone substances can be detected at the same time, and compared with literature methods, the method is high in specificity, good in precision, high in accuracy, simple and easy to implement and high in operability.

The invention relates to the technical field of Stefan acid purification, in particular to a method for purifying Stefan acid from a dinitrobenzene nitration byproduct mixture, which comprises the following steps: S1, dissolving the dinitrobenzene nitration byproduct mixture in water, adjusting the pH value to be alkaline, and filtering to obtain filtrate and filter residue dinitrobenzene solid; s2, adding the filtrate into an organic solvent, extracting, separating liquid, and retaining a water phase; and S3, adjusting the pH value of the water phase to be acidic, heating for acid precipitation, and then cooling for crystallization to obtain a mixed crystal of Stefan acid and picric acid. And S4, heating and mixing the mixed crystal and toluene, and filtering to obtain the high-purity Stefan acid. According to the method, efficient separation is realized through a two-step core process of'alkali dissolution-acidification 'and'selective dissolution'. In the final product, the content of dinitrobenzene can be reduced to 0%, the content of picric acid can be reduced to 1% or below, and the purity of Stefan acid can reach 99% or above.

The application belongs to the technical field of near-infrared luminescence and ultrasonic treatment materials, discloses a kind of activatable acoustic power nano materials based on conjugated polymer and its preparation method and application, comprising the following steps: 2,6-di (trimethyl tin) -4,4-di (2-ethylhexyl) -dithiophene and cyclopentadiene, 4,7-dibromo-5,6-dinitrobenzo [c] [1,2,5] thiazole, catalyst tetra (triphenylphosphine) palladium are added into reaction tube, toluene is added, and the reaction product is settled with methanol under nitrogen protection, to obtain conjugated polymer;Degradable mesoporous silica is used to wrap to realize the water-soluble of molecule, and the corresponding activatable acoustic treatment reagent is obtained.The material disclosed in the application can be used for activatable acoustic dynamics treatment guided by near-infrared two-zone imaging, which helps to improve the specificity of tumor treatment, and mesoporous silica wrapping can also be used for drug loading and transport.

The invention discloses a flavonol-based fluorescent probe for continuously detecting hydrogen sulfide and hypochlorous acid as well as a preparation method and application of the flavonol-based fluorescent probe. The flavonol-based fluorescent probe is 3-(2, 4-dinitrophenoxy)-7-(4-(diphenylamino) phenyl)-2-(4-(thiomorpholinophenyl) chromone, and the structural formula of the flavonol-based fluorescent probe is shown in the specification. According to the invention, 7-(4-(diphenylamino) phenyl)-3-hydroxy-2-(4-thiomorpholinophenyl) chromone is used as an initial raw material, and the 7-(4-(diphenylamino) phenyl)-3-hydroxy-2-(4-thiomorpholinophenyl) chromone and 2, 4-dinitrofluorobenzene are subjected to nucleophilic substitution reaction to obtain the compound 3-(2, 4-dinitrophenoxy)-7-(4-(diphenylamino) phenyl)-2-(4-(thiomorpholinophenyl) chromone. The compound is firstly subjected to selective thiolysis reaction under the action of hydrogen sulfide, the fluorescence color of a solution of the compound is changed from colorless to bright orange under the irradiation of ultraviolet light with the wavelength of 365 nm, then hypochlorous acid is continuously added into the solution, and the compound can be further subjected to specific oxidation reaction with the hypochlorous acid, so that the compound can be obtained. And the fluorescence color of the solution is changed from bright orange to bright cyan. Therefore, the compound can be used as a fluorescent probe for continuously detecting hydrogen sulfide and hypochlorous acid, has the advantages of low detection limit, high response speed, good light stability, wide pH application range and the like, and shows a good application prospect.

The present invention provides novel 2,4-dinitrophenol (DNP) derivatives and prodrugs thereof as modulators of mitochondrial function. The present invention also provides pharmaceutical compositions comprising the compounds of the present invention and methods for using the same to treat various diseases and conditions associated with or related to mitochondrial dysfunction (e.g., obesity, diabetes, insulin resistance, liver disease, heart or kidney failure, neurodegenerative diseases, and aging-related diseases, including but not limited to sarcopenia, osteoporosis, etc.).

The invention discloses an unsymmetrical dimethylhydrazine detection method based on a 2, 4-dinitrobenzaldehyde chromogenic reaction, a reagent and a sensing film, and belongs to the field of dangerous chemical detection, the embodiment of the invention further provides the unsymmetrical dimethylhydrazine detection method based on the 2, 4-dinitrobenzaldehyde chromogenic reaction, a to-be-detected sample is in contact with an absorption liquid, and the absorption liquid is detected through the unsymmetrical dimethylhydrazine detection method based on the 2, 4-dinitrobenzaldehyde chromogenic reaction. Observing whether a color change from yellow to brownish red appears; the absorption liquid comprises 2, 4-dinitrobenzaldehyde, an acidic medium and a solvent. The existence of unsymmetrical dimethylhydrazine is judged by observing whether the color change from yellow to brownish red appears or not and observing the color depth or the size of a color change area. According to the method, the unsymmetrical dimethylhydrazine as low as 1 ppm in a gas phase and as low as 0.1% in a liquid phase can be subjected to rapid and distinct yellow-to-brown yellow chromogenic reaction, and common interference such as 50 ppm ammonia gas can be effectively inhibited in an acidic environment.

The invention belongs to the technical field of fine chemical engineering, and particularly discloses a method for synthesizing mixed phenylenediamine through hydrogenation of mixed dinitrobenzene. The method comprises the following steps: adding mixed dinitrobenzene, a polar solvent and a catalyst into a jet type supergravity multi-phase reaction device, enabling the mixed dinitrobenzene and the polar solvent to circularly flow in the jet type supergravity multi-phase reaction device in a hydrogen atmosphere, and reacting to obtain mixed phenylenediamine; the jet type supergravity multiphase reaction device comprises an annular reaction kettle, a jet ejector, a supergravity rotary drum, a heat exchanger, a circulating pump, a gas circulating pipeline and an ejector air suction port. The synthetic method of mixed phenylenediamine disclosed by the invention has the characteristics of high mass and heat transfer efficiency, substantial improvement of hydrogenation efficiency, intrinsic safety, greenness and high efficiency, and has a wide industrial application prospect.

The invention belongs to the technical field of nitration reaction product separation, and particularly relates to a mixed dinitrobenzene extraction separation process applied to nitration reaction. Through three-section gradient dilution and accurate concentration control, the problem of incomplete separation caused by high solubility of high-concentration sulfuric acid to nitrobenzene is effectively solved, meanwhile, the hidden danger of pipeline blockage caused by dinitro compound crystallization is eliminated, and the production safety and the product purity are remarkably improved. According to the invention, a complete material closed-loop system is established, the extractant-nitrobenzene is directly reused for nitration reaction after deep dehydration and impurity removal, and the waste sulfuric acid is completely returned to a production system for recycling after being treated, so that the utilization rate of raw materials is greatly improved, and the discharge of waste acid is reduced. According to the method, key parameters such as temperature, concentration and flow are monitored in real time, so that the nitration reaction yield is stabilized at 97.2% or above, the operation cycle of the device is effectively prolonged, and reliable technical guarantee is provided for industrial production.

The invention belongs to the technical field of propellants, and provides a boron-containing fuel-rich propellant and a preparation method thereof.The propellant adopts fluorine-containing composite boron powder to replace common boron powder; a combination of hydroxyl-terminated polybutadiene and hydroxyl-terminated poly (polyethylene glycol succinate) is adopted as an adhesive; hydroxyl-terminated polyethylene glycol terephthalate containing a benzene ring rigid structure is adopted as a reinforcing agent, a polyethylene glycol chain segment, epoxy resin on the surface of boron powder and an oxidizing agent form a hydrogen bond, and hydroxyl-terminated polyether ester fixes a solid filler in a curing network and adjusts the crosslinking density at the same time; chemical bonds are generated on the surfaces of filler particles, so that the modulus of the propellant is further improved; the perfluoro diacid diester is used as a plasticizer, so that the burning efficiency is improved while the processing property of the propellant is not influenced; ferric polyacrylate, 2, 4-dinitrophenoxy ethanol and the like are used as combustion regulators to promote efficient oxidation of the boron powder. The boron-containing fuel-rich propellant provided by the invention can solve the demand problem of a solid ramjet engine on a high-modulus boron-containing fuel-rich propellant.

The present application discloses a co-crystal of omeprazole and 3,5-dinitrobenzoic acid, wherein the molar ratio of omeprazole to 3,5-dinitrobenzoic acid is 1:1, and the co-crystal has higher stability, in-vivo absorption speed and onset speed compared with omeprazole.

This invention belongs to the field of fine chemical synthesis technology and relates to a method for preparing 2,4-diaminodiphenylamine, an intermediate in p-phenylenediamine antioxidants. Aniline and m-dinitrobenzene undergo a catalytic nucleophilic substitution reaction under negative pressure to obtain a reaction system with 2,4-dinitrodiphenylamine as the main product. The reaction system with 2,4-dinitrodiphenylamine as the main product is diluted with methanol and then subjected to catalytic hydrogenation. After the reaction, post-treatment yields 2,4-diaminodiphenylamine. This invention uses m-dinitrobenzene as the reactant, which is halogen-free and does not produce halogen-containing wastewater. It also has lower requirements for the corrosion resistance of production equipment, higher atom economy, and is more in line with the concept of green chemistry. The solvent and catalyst in this invention are recyclable, resulting in low cost.

The invention provides a method for preparing 1, 2, 3-trifluorobenzene, which comprises the following steps: by taking 1, 2, 3-trichloro-4, 6-dinitrobenzene as a starting material, carrying out fluorination reaction, hydrogenation reduction reaction, diazotization reaction and deamination reaction to obtain the 1, 2, 3-trifluorobenzene. The initial raw material can be prepared from 1, 2, 3-trichlorobenzene through a nitration reaction, and the preparation method has the advantages of high yield, few three wastes, high safety and the like, is a green method which is high in selectivity, high in economical efficiency and environmentally friendly, and is suitable for industrial production.

The invention relates to the field of underground engineering, in particular to a waterproof corrosion-resistant anti-cracking plugging material for underground engineering as well as a preparation method and application of the waterproof corrosion-resistant anti-cracking plugging material. The problems that an existing plugging material is poor in corrosion resistance and insufficient in anti-cracking capacity are solved. A polyethylene glycol grafted terpyridyl benzotriazole copolymer is added into the plugging material, and the preparation method of the polyethylene glycol grafted terpyridyl benzotriazole copolymer comprises the following steps: firstly, reacting 2, 4-dinitrobenzaldehyde with 2-acetylpyridine, and then reducing with stannous chloride dehydrate to obtain diaminophenyl terpyridyl; the preparation method comprises the following steps: carrying out a series of reactions on 2, 5-methyl benzotriazole to obtain epoxy benzotriazolyl oxadiazole, and carrying out a cross-linking reaction on diaminophenyl terpyridyl, polyethylene glycol diglycidyl ether and epoxy benzotriazolyl oxadiazole to obtain a polyethylene glycol grafted terpyridyl benzotriazole copolymer. The corrosion resistance, crack resistance and impermeability of the material are improved, and the long-term stability and reliability of the material are improved.

The application discloses a 2,4-dinitrophenol / Pb (II) double-template imprinted polymer adsorbent and a preparation method thereof. The double-template imprinted monolithic adsorbent is prepared by using in-situ polymerization technology, 2,4-dinitrophenol and Pb (II) are used as imprinting templates, 4-vinylpyridine and dimethylaminopropyl acrylamide are used as functional monomers. The functional monomers and the templates are effectively combined through hydrogen bond action and coordination action, and then a porogen and a crosslinking agent are added to react to form a polymer. The double templates are eluted, and a three-dimensional cavity structure with specific recognition function is left. The specific binding sites and shapes on the cavity are used to realize selective extraction of NP S and Pb (II). Meanwhile, the prepared double-template imprinted adsorbent has the advantages of simple operation, good permeability, low cost and wide application range, and therefore the double-template imprinted polymer monolithic adsorbent prepared by the application has good practical application value.

The utility model discloses an electric connector. Relates to the connector field. Comprising an insulating shell; a terminal housed inside the housing and connected to an end portion of a conductive wiring substrate; an alignment plate which is mounted on the housing and has a terminal accommodating hole into which the front end portion of the terminal is inserted; the terminal includes: a terminal body extending toward a conductor portion along a surface of the wiring substrate; an extension portion extending from the terminal body in a direction intersecting and separating from the surface of the wiring substrate; the extension part is inserted into the terminal accommodating hole of the alignment plate; and the shell is covered with a 3, 5-dinitrobenzoyl chloride coating. According to the electric connector provided by the utility model, the terminal body is provided with the extension part which extends along the cross direction of the surface of the wiring substrate, and the extension part is inserted into the terminal accommodating hole of the alignment plate, so that the extension part of the terminal can be corrected through the alignment plate, thereby being positioned to a preset position and contacted with the wiring substrate. Thus, stable connection between the terminal and the wiring substrate can be realized, and the reliability of the connector can be improved.

The invention discloses a ternary component potassium-based supramolecular energetic material as well as a preparation method and application thereof, and belongs to the technical field of energetic material development. The preparation method comprises the following steps: 1) adding 4, 5-dinitrobenzo-18-crown-6, potassium nitrate and nitro potassium into a solvent according to a molar ratio of 1: 1: 1, and stirring and filtering to obtain an assembly solution; and 2) adjusting the gas pressure to 0.1-0.5 Mpa and the temperature to 70-90 DEG C, pumping the assembled solution into a spray head through a feed pump, dispersing the assembled solution into fine fog drops under the action of high-pressure hot air flow, rapidly volatilizing the solvent, and rapidly combining, assembling and gathering crystals to form the dry 4, 5-dinitrobenzo 18-crown-6 / potassium nitrate / nitrate imitated potassium supramolecular energetic material. The invention provides the novel ternary component supramolecular energetic material, the preparation method is simple and rapid, the 4, 5-dinitrobenzo 18-crown-6 / potassium nitrate / nitrate imitated potassium supramolecular energetic material can be rapidly prepared through pressure-assisted assembly, the process is simple and easy to operate, the preparation efficiency is high, and continuous preparation is easy.

This invention relates to the field of organic synthesis technology, specifically disclosing a method for preparing N-(2,4-diaminophenyl)-4-aminobenzamide. The method involves using N-(2,4-dinitrophenyl)-4-nitrobenzamide as a raw material, adding a catalyst, buffer salt, and water, mixing the mixture, and then purging with nitrogen gas to maintain pressure. The nitrogen gas is then replaced with hydrogen gas, and a hydrogenation reaction is carried out under a hydrogen atmosphere. After the reaction is complete, an acid is added to quench the reaction, the catalyst is removed by filtration, and then an alkali is added to adjust the pH to above 8. The mixture is then filtered to obtain crude N-(2,4-diaminophenyl)-4-aminobenzamide. The crude product is purified by recrystallization and finally dried to obtain N-(2,4-diaminophenyl)-4-aminobenzamide. The method provided by this invention has high selectivity, few side reactions, protects the amide bond from hydrolysis, and produces a product with high purity.

The method for simultaneously determining multiple nitrophenol compounds in different food matrices according to the present invention involves preparing a series of mixed solutions with different concentrations of 2,4-dinitrophenol, 2,5-dinitrophenol, 2,6-dinitrophenol, 3,4-dinitrophenol, and 3,5-dinitrophenol using acetonitrile-acetic acid solution as standard samples; the food matrices to be tested are then subjected to extraction and purification treatment. The sample was obtained through a process; then, high-performance liquid chromatography-tandem mass spectrometry was used to detect the sample and standard to obtain the concentrations of 2,4-dinitrophenol, 2,5-dinitrophenol, 2,6-dinitrophenol, 3,4-dinitrophenol, and 3,5-dinitrophenol in the sample. The content of each nitrophenol compound in the food matrix was then calculated based on the concentrations of 2,4-dinitrophenol, 2,5-dinitrophenol, 2,6-dinitrophenol, 3,4-dinitrophenol, and 3,5-dinitrophenol in the sample.

The invention relates to the technical field of analytical chemistry detection, in particular to a color developing agent for rapidly measuring the content of lignan and a preparation method thereof.The color developing agent is composed of a liquid component and a solid component dispersed in the liquid component, and the liquid component comprises the following components by volume: a color developing agent, a 2, 4-dihydroxy-2, 4-dihydroxy-2, 4-dihydroxy-2, 4-dihydroxy-2, 4-dihydroxy-2, 4-dihydroxy-2, 4-dihydroxy-2, 4-dihydroxy-2, 4- adding an acidic ethanol solution of 2, 4-dinitrophenylhydrazine; the nano signal enhancer is surface modified gold nanorod sol with the concentration of 3 to 8 nM; the catalytic oxidant is iron (III) porphyrin with the concentration of 0.05 to 0.15 mmol / L; a dispersion stabilizer: polyethylene glycol 400 with a volume fraction of 1-3%; the solvent system is a mixed solvent of a buffer solution with the pH value of 2.0-3.0 and ethanol; the solid component is lignan molecularly imprinted polymer microspheres, and the concentration of the lignan molecularly imprinted polymer microspheres in the color developing agent is 0.5-2.0 g / L. According to the method, lignans can be conveniently detected, the sensitivity is high, the molecularly imprinted polymer provides specific recognition capability, and rapid, high-sensitivity and high-selectivity colorimetric detection on lignan components is realized.

The invention relates to the technical field of organic chemical synthesis, in particular to a preparation method of 3, 4 '-diaminodiphenyl ether.The preparation method comprises the steps that S1, under inert gas and in a first solvent, m-dinitrobenzene and p-acetamidophenol are subjected to a heating reaction under the condition of a weak base catalyst, and 3-nitro-4-acetamido diphenyl ether is prepared; s2, in a second solvent, the 3-nitro-4-acetamido diphenyl ether is subjected to a hydrogenation reduction reaction, and 3-amino-4-acetamido diphenyl ether is prepared; and S3, dissolving the 3-amino-4-acetaminodiphenyl ether in an alcohol solvent system, adding alkali and water, controlling the reaction temperature, carrying out a hydrolysis reaction, and after the reaction is finished, carrying out post-treatment to obtain the 3, 4 '-diaminodiphenyl ether. The preparation method provided by the invention has the advantages of easily available raw materials, low price, good selectivity and high product yield, and is more suitable for industrial production by comprehensively considering economical efficiency and safety.

This invention discloses the application of a eutectic material based on ethyl column[5] aromatics in the visual adsorption separation of a mixture of n-pentane and isoprene. The macrocyclic eutectic material formed by ethyl column[5] aromatics and 3,5-dinitrobenzonitrile is used to selectively adsorb and separate n-pentane from a mixture of n-pentane and isoprene. During the adsorption and separation of n-pentane and isoprene, a visual color change is observed. The separation process does not require distillation, has low energy consumption, and is fast. The visible color change phenomenon during the adsorption of n-pentane provides visual monitoring of the separation process. Furthermore, the eutectic material used has high stability, can be recycled, and has stable separation performance.

The application discloses a method for synthesizing 2,4-dinitroanisole based on a channel type continuous flow. The method uses a methanol solution of 2,4-dinitrochlorobenzene as a first mixed solution, an aqueous sodium hydroxide solution as a second mixed solution, then controls parameters of a micro-channel reactor, pumps the first mixed solution and the second mixed solution into the micro-channel reactor for mixing and reaction, finally cools and collects the mixed solution by using ice water, and filters and dries to obtain 2,4-dinitroanisole. In the method, the conversion rate of 2,4-dinitrochlorobenzene is high, the yield of 2,4-dinitroanisole is high, the quality of 2,4-dinitroanisole is high, the synthesis process is environmentally friendly, and safety is good.

The utility model discloses a nitrobenzene continuous isothermal nitration reaction system based on dilute nitric acid, which comprises a first circulation nitrator, a second circulation nitrator, a first nitration kettle, a second nitration kettle and a third nitration kettle which are connected in sequence, and is characterized in that an acidic benzene outlet pipeline of an acidic benzene storage tank is connected with an acid benzene mixer through a pump; a waste acid outlet pipeline of the waste acid head tank is connected with a circulating acid cooler, a cooling acid outlet pipeline of the circulating acid cooler is divided into two branch pipes, one branch pipe is connected with an acid-benzene mixer, and an outlet pipeline of the acid-benzene mixer is connected with an acid-benzene inlet pipeline of the first circulation nitrator. Low-temperature nitration is carried out firstly, then the nitration temperature is gradually increased, generation of by-products dinitrobenzene and nitrophenol is reduced, and continuous automatic production can be achieved.

The invention discloses a ratio type near-infrared fluorescent probe Dn-NIR-Sec of selenocysteine as well as a preparation method and application of the ratio type near-infrared fluorescent probe Dn-NIR-Sec. The chemical structural formula of the ratio type near-infrared fluorescent probe Dn-NIR-Sec is shown as a formula (I). The preparation method comprises the following steps: condensing a compound 1 shown as a structural formula (1) with cyclohexanone under an acidic condition to obtain a compound 2 shown as a structural formula (2); the preparation method comprises the following steps: firstly, preparing a compound 2, then condensing the compound 2 and a compound 3 with a structural formula as shown in a formula (3) to obtain a ratio-type near-infrared dye platform Dn-NIR-OH, and finally reacting with 2, 4-dinitrobenzenesulfonyl chloride to obtain the ratio-type near-infrared dye platform Dn-NIR-OH. Experimental results show that the ratio-type near-infrared fluorescent probe Dn-NIR-Sec can complete rapid fluorescent response to Sec within 5 minutes, real-time dynamic detection is facilitated, selective recognition performance on selenocysteine is remarkable, light stability is good, and meanwhile the ratio-type near-infrared fluorescent probe Dn-NIR-Sec has good cell membrane permeability and low cytotoxicity. Therefore, the probe can be widely applied to the fields of biological detection and the like as a fluorescence detection tool.

The present invention provides novel 2, 4-dinitrophenol (DNP) derivatives and prodrugs thereof as modulators of mitochondrial function. The invention also provides pharmaceutical compositions comprising the compounds of the invention and methods of their use in the treatment of various diseases and conditions associated or associated with mitochondrial dysfunction (e.g., obesity, diabetes, insulin resistance, liver disease, heart failure or renal failure, neurodegenerative disease, or aging-related disease).

This invention discloses an interpenetrating polymer network (IPN) material for the efficient purification of volatile organic compounds (VOCs) and its preparation method. The method first employs a B-H (-NO2) coupling method, using tris(4-nitrophenyl)amine or p-dinitrobenzene as the core component, and various aromatic amine linkers to construct a primary conjugated microporous polymer network (N-CMPs) under a palladium catalysis system. Subsequently, through post-molecular weaving and expansion technology, secondary crosslinking is carried out using p-phenylenedichlorobenzyl or acyl chloride external crosslinking agents under Lewis acid catalysis, significantly improving the density and specific surface area of ​​the framework. The prepared HCCP1-X series materials exhibit a saturated adsorption capacity of 961 mg / g for toluene and 895 mg / g for ethyl acetate at 25 °C, providing a new pathway for the development of highly efficient VOCs adsorbents.