150 results about "Hydrazide" patented technology

The invention discloses HA-PAS hydrogel for enhancing cartilage repair of early osteoarthritis and a preparation method of the HA-PAS hydrogel. According to the hydrogel, formylated hyaluronic acid, hydrazide modified low-methoxyl pectin and phenylboronic acid modified alginate form a ternary polysaccharide skeleton, a double-dynamic cross-linked network is formed through acylhydrazone bonds and boric acid ester bonds, and a triple network structure is formed by combining permanent cross-linking catalyzed by horse radish peroxidase. The hydrogel integrates functional components such as nano-selenium, a pulullan-strontium chelate and a mesenchymal stem cell source exosome, so that multiple effects of resisting oxidation, resisting inflammation, promoting cartilage differentiation and repairing subchondral bones are achieved. The compression modulus of the hydrogel is 0.8-1.5 MPa, and the hydrogel can be injected for in-situ gelling and MMP responsive degradation, shows an excellent cartilage repair effect in animal experiments, and provides a new solution for treatment of early osteoarthritis.

The invention discloses a preparation method of a photo-thermal conversion-phase change heat storage polyurethane flexible film, and relates to the technical field of polyurethane phase change materials. According to the invention, polyethylene glycol is used as a polymeric monomer and a phase change heat storage substrate, diisocyanate and dimethylolbutyric acid are used as reaction monomers, any one of 3, 3-dithio-bis-propionyl hydrazide or (R, R)-3, 3 '-diseleno-bis (2-aminopropionic acid) is used as a cross-linking agent, and transition metal carboxylate and a nano photo-thermal conversion agent are introduced to prepare the phase change heat storage material. And the polyurethane flexible film with photo-thermal conversion-phase change heat storage is prepared. A hydrazide group at the tail end of a cross-linking agent and an isocyanate group are subjected to nucleophilic addition reaction to generate a hydrazide-urea structure of which the main chain contains disulfide bonds and constructs multiple hydrogen bonds, and meanwhile, a metal carboxylate coordination bond is introduced, so that the film is endowed with an excellent mechanical response effect in a wide temperature range; the nano photo-thermal conversion agent is added into the system, so that the system has good photo-thermal conversion performance.

The invention generally relates to nuclear transport modulators, e.g., CRM1 inhibitors, and more particularly to a compound represented by structural formula I:or a pharmaceutically acceptable salt thereof, wherein the values and alternative values for the variables are as defined and described herein. The invention also includes the synthesis and use of a compound of structural formula I, or a pharmaceutically acceptable salt or composition thereof, e.g., in the treatment, modulation and / or prevention of physiological conditions associated with CRM1 activity.

The invention relates to the technical field of high polymer materials, and discloses a furyl polyurethane adhesive and a synthesis method thereof, polymer polyol is used as a soft segment, isocyanate and two specific furyl chain extenders are used as hard segments, polymerization is performed through a one-step method, and the method has the advantages of simple process, short flow, mild reaction conditions and the like. Wherein a furan ring and an amide group of the two specific furyl chain extenders endow the material with rigidity and excellent bonding performance, and form a high-density hydrogen bond network with a hydrazide group, so that the mechanical strength, the toughness and the bonding performance of the material are remarkably improved. By regulating and controlling the proportion of the components, the rigidity and flexibility of the material can be effectively balanced, so that the polyurethane adhesive with excellent comprehensive performance is prepared. The furyl polyurethane adhesive prepared by the invention has relatively high adhesion strength and mechanical strength, and can be applied to the fields of buildings, automobile manufacturing, medical treatment, packaging, aerospace, electronics and the like.

A water-based coating composition comprising: water, (a) a binder comprising (a1) a core-shell latex copolymer with side-mounted carbonyl groups, and (b) a crosslinker comprising (b1) at least one polyhydrazide compound having at least two hydrazide groups of the formula -C(=O)-NH-N(R h )(R i ) includes, where R h and R i independent H or C1-C 12 -Alkyl groups, where the molar ratio of hydrazide groups to carbonyl groups is 5:1 to 1:5 in the composition.

The invention discloses a 3D printing polyurethane elastomer as well as a preparation method and application thereof, and relates to the technical field of high polymer materials. The polyurethane elastomer is composed of a prepolymer containing a dynamic hydrazide urea bond and a hindered urea bond and a monomer containing primary amine, the prepolymer takes polyether polyol and diisocyanate as basic raw materials, a dynamic hydrazide urea bond hard segment is introduced into the prepolymer through a hydrazide chain extender, a side chain is introduced through glycidyl methacrylate, and the primary amine-containing monomer is prepared. A dynamic hindered urea bond and a photocuring group are introduced through an acrylate end-capping reagent, and a reactive diluent and a photoinitiator are matched to optimize the forming performance. In the preparation process, a prepolymer and a primary amine-containing monomer are mixed and then subjected to 3D printing forming, in the low-temperature stage, reversible exchange of dynamic hydrazide urea bonds and hindered urea bonds is promoted to heal interlayer defects, and in the high-temperature stage, the hindered urea bonds are triggered to break and react with primary amine to form a stable cross-linked network. The 3D printing polyurethane elastomer has excellent rebound resilience, mechanical strength and hydrophobic effect.

The application belongs to the field of citrus cultivation, and particularly relates to a citrus coloring and sweetening composition and application. The main components of the citrus coloring and sweetening composition are maleic hydrazide and ethylene, and the mass ratio of the maleic hydrazide to the ethylene is 2:(1-4). The application is prepared by compounding maleic hydrazide and ethylene. The test results show that the application can promote early coloring of citrus, prevent reverse acidification of citrus after application of maleic hydrazide, increase average sugar content of citrus, has no negative effect on growth of citrus, has no pollution to the environment, and can be widely used in planting and production of different regions and different citrus varieties.

This invention belongs to the field of mineral flotation technology, and discloses a flotation collector for non-ferrous metal sulfide ores, its preparation method, and its application. The collector uses O,O-dialkyldithiophosphate as a starting material, and reacts sequentially with a halocarboxylic acid ester, hydrazine hydrate, potassium hydroxide, and carbon disulfide in anhydrous ethanol in a three-step reaction to obtain the target product, O,O-dialkyldithiophosphate hydrazide-N′-dithiocarbamate potassium. Its molecular structure simultaneously contains three active groups: a dithiophosphate group, an hydrazide group, and a dithiocarbamate group. This invention achieves efficient process connection and smooth transition by optimizing the material ratio, temperature, and time of each reaction step, and has advantages such as mild reaction conditions, simple operation, few side reactions, high yield, and stable product. The prepared collector exhibits excellent collecting performance and good selectivity for non-ferrous metal sulfide ores such as chalcopyrite, and is suitable for widespread application in sulfide ore flotation processes.

The invention provides a preparation method of a bio-based reversible cross-linked polyurethane hot melt adhesive. The method comprises the following steps: firstly, carrying out polymerization reaction on bio-based polyol PO3G (poly trimethylene ether glycol) and isophorone diisocyanate which are used as raw materials to prepare an isocyanate-terminated bio-based prepolymer; then, diethyl toluenediamine and isophthaloyl hydrazine are adopted as a mixed chain extender for a chain extension reaction, and after drying treatment, the bio-based polyurethane hot melt adhesive is obtained. The bio-based hot-melt adhesive prepared by the invention is suitable for hot-melt sealants in the field of electronic devices. The adhesive shows good bonding performance to a stainless steel base material, the tensile shear strength reaches 0.45-0.5 MPa, the adhesive has excellent reversible disassembly characteristic, and convenient separation of a bonding interface can be achieved by heating at 100 DEG C for 10 minutes.

A film-forming thermoset coating composition includes: (a) an aqueous medium; and Option 1 and / or Option 2 as follows: Option 1: (b1) polyurethane-acrylate core-shell particles including a polymeric acrylic core at least partially encapsulated by a polymeric shell including urethane linkages, where the polymeric shell includes an acid functional group and two or more hydrazide functional groups, where the polymeric shell is covalently bonded to at least a portion of the polymeric core; and (c1) (i) formaldehyde; (ii) polyformaldehyde; and / or (iii) a compound that generates formaldehyde; Option 2: (b2) polyurethane-acrylate core-shell particles including a polymeric acrylic core at least partially encapsulated by a polymeric shell including urethane linkages, where the polymeric shell includes an acid functional group and two or more N-methylolated hydrazide functional groups, where the polymeric shell is covalently bonded to at least a portion of the polymeric core.

A combination for use in treating cancer is provided. The combination comprises a therapeutically effective amount of an inhibitor of nuclear import protein Karyopherin Beta 1 (Kpnβ1) such as the substituted pyrrolo[2,3-b]quinoxalines of Formula I and a therapeutically effective amount of an inhibitor of nuclear export protein Chromosome Maintenance 1 (Crm1) such as the hydrazide- containing compounds of Formula II. The combination therapy provides an enhanced anti-cancer therapeutic effect compared to the effect of each of the nuclear transport inhibitors administered alone.

The present application relates to the technical field of pesticides, and discloses a chromene aryl hydrazide derivative, a preparation method and application thereof, a structural general formula of the chromene aryl hyydrazide derivative is as formula (I); the preparation method is as follows: taking p-hydroxybenzaldehyde as raw material, and obtaining the chromene aryl hydrazide compound through substitution reaction, cyclization reaction, oxidation reaction, acylation reaction and hydrazinolysis reaction. The chromene aryl hydrazide compound is used for preparing an agricultural bacteriostatic agent. The present application combines aryl hydrazine and chromene skeleton by using the pharmacophore splicing principle in medicinal chemistry, and designs and synthesizes a series of chromene aryl hydrazide compounds. The bacteriostatic activity test result shows that the compounds have excellent bacteriostatic activity, and can be used as active ingredients for preparing a plant pathogenic fungus fungicide.

The invention relates to the technical field of structural adhesives, in particular to an epoxy composition capable of being used for bonding a camera module support and a preparation method of the epoxy composition, and the epoxy composition comprises the following components in parts by weight: 7-10 parts of epoxy resin; 20-25 parts of flexible epoxy resin; 5-10 parts of a core-shell epoxy resin toughening agent; 20-25 parts of a compound filler; 30 to 31 parts of organic hydrazide; and 8-9 parts of a modified amine adduct. The flexible epoxy resin has at least one structural characteristic of a long-chain polyether structure and an indene structure. The compound filler comprises calcium carbonate and silicon dioxide. The epoxy composition capable of being used for bonding the camera module support has the advantages of low precipitation, low curing shrinkage, high bonding strength, low modulus and excellent falling resistance, the reliability of the camera module support structure can be remarkably improved, and the epoxy composition is suitable for application environments of various miniature high-performance camera modules.

The present invention provides an inkjet ink in which the colorant is stably and highly dispersed, has excellent injection stability (droplet formation and droplet recovery), and can improve the texture and friction fastness of printed materials. [Solution] An inkjet ink comprising a urethane resin having (A) a structural unit derived from polyisocyanate, (B) a structural unit derived from polyol, and (C) a structural unit derived from polyamine, and an organic solvent, wherein the (B) polyol comprises (B1) a polyether polyol and (B2) a diol compound having a carboxyl group and / or a carboxylate group, and the (C) polyamine comprises (C1) a first polyamine having two groups selected from an amino group, an imino group, and a hydrazide group, and (C2) a second polyamine having three or four groups selected from an amino group, an imino group, and a hydrazide group, and the mass ratio of the organic solvent to the urethane resin (mass of organic solvent / mass of urethane resin) is 1.0 or more.

There is provided a resin composition including a resin having an alkyl group on a side chain of a molecule thereof, an inorganic filler and an antioxidant, wherein the antioxidant is either of a hydrazide-based antioxidant or a combination of a hindered phenol-based antioxidant and an organic metal chelate-based antioxidant.

The invention relates to a thermally expandable composition comprising: a) At least one thermoplastic polymer TP and / or at least one solid rubber R and b) At least one polymeric blowing agent BA selected from the group consisting of sulfonyl hydrazide-functionalized polymers, sulfonyl semicarbazide-functionalized polymers, carbamate-functionalized polymers, and ureido carbamate-functionalized polymers, wherein the polymeric blowing agent BA has a number average molecular weight (Mn) determined by gel permeation-chromatography (GPC) using polystyrene 0 as standard of at least 500 g / mol, preferably at least 750 g / mol.

The present application belongs to the technical field of herbicide safener, and particularly relates to the use of chlorindole hydrazide as a herbicide safener, chlorindole hydrazide as a safener of nicosulfuron, carfentrazone-ethyl, benzenesulfonamide and quizalofop-p-ethyl, which can relieve or eliminate the crop phytotoxicity caused by the above herbicides, and is applied after or before the crop phytotoxicity is caused. The application amount of chlorindole hydrazide (converted into the original drug) is 1-2 g / mu, the mass concentration of chlorindole hydrazide is 0.00667-0.01333% when applied, and a very good control effect can be achieved.

The invention relates to a novel chemical cross-linking agent with mass spectrum fragmentable trehalose disaccharide as a skeleton structure and a preparation method thereof. The cross-linking agent disclosed by the invention has the following characteristics: 1) trehalose disaccharide is used as a skeleton structure, so that the cross-linking agent has excellent biocompatibility; 2) the trehalose skeleton has a pair of symmetrical mass spectrum fragmentable glucosidic bonds, so that a cross-linked peptide fragment can be simplified into a conventional peptide fragment modified by a cross-linking agent fragment; 3) the enrichment of the cross-linked peptide fragment can be realized by the trehalose skeleton under the condition of not adding an enrichment handle; and 4) active groups of the cross-linking agent comprise but not limited to a plurality of reactive groups such as succinamide ester, diaziridine, phenylsulfonyl fluoride, hydrazide group, amino group, hydroxylamine group and the like, and chemical cross-linking of a plurality of amino acids except lysine is realized. The trehalose cross-linking agent disclosed by the invention is applied to the field of proteomics, and provides technical support for realizing large-scale analysis of a protein complex in a complex sample, spatial structure analysis of protein and a protein-protein interaction network.

The invention discloses a long-side-chain internal-plastic toughened polyurethane elastomer as well as a synthesis method and application thereof, and belongs to the technical field of high-performance elastomers. According to the invention, a long side chain toughening element is introduced as a cohesive reinforcing unit, binary hydrazide is adopted as a chain extender for cooperation, and the long side chain toughening element reacts with an isocyanate prepolymer to construct a strong hydrogen bond cross-linked polymerization network. The structure integrates the processability / stretchability / low temperature resistance of the flexible chain segment and the high toughness / thermal stability / chemical resistance of the long side chain toughening element. By regulating and controlling the component proportion of the soft chain segment, the stretchability and mechanical toughness of the material can be balanced and rejected, so that high Td and chemical resistance are maintained, and on the premise of not reducing the modulus and tensile strength of the material, the low-temperature toughness is improved, the combination of rigidity and toughness is realized, and the defect of insufficient toughness of the existing commercially available polyurethane elastomer is overcome.

The invention discloses chloroindole hydrazide-loaded nanogel and a preparation method and application thereof, and relates to the technical field of pesticides, the chloroindole hydrazide-loaded nanogel is successfully prepared, CHI can be stably loaded, slow release is realized, and the chloroindole hydrazide-loaded nanogel has excellent leaf adhesiveness, can resist rain wash and avoid loss of pesticide effect, and can be used as a pesticide for preventing and treating diseases. The application pain point of CHI and the defects of a traditional nano-carrier are overcome; the nano-scale characteristic assists plant cell endocytosis and uptake, breaks through the transport limitation of cell membranes, and gives full play to the high induced resistance activity of CHI. High-speed centrifugal purification is not needed in the preparation process, the process is simplified, the yield is increased, large-scale production is adapted, and meanwhile energy consumption and cost are reduced. Compared with a traditional nano-carrier, the nano-gel does not need expensive precursors or complex modification, is good in dispersity and free of the agglomeration problem, preparation is low in energy consumption and pollution, the comprehensive performance is more suitable for practical application of pesticide carriers, and a solution with practicability and economical efficiency is provided for efficient prevention and treatment of plant virus diseases.

The invention discloses a preparation method and application of a coumarin-hydrazide-based semi-sandwich type iridium and ruthenium complex, the structural formula of the complex is as shown in formula (I), the complex takes a coumarin-hydrazide derivative as an NO bidentate ligand, and an oxygen coordination atom in the ligand is derived from hydroxyl of a coumarin mother nucleus; iridium or ruthenium is used as a metal center, benzene is used as a unique solvent, alkali does not need to be added additionally under the protection of nitrogen, and the ligand can be prepared through a coordination reaction of the ligand and a metal dimer. The complex shows good anti-cancer activity, the drug effect of the complex is close to that of cis-platinum, and the complex has the potential value of becoming a novel anti-cancer drug.

The invention provides a drug carrier based on N-acetylglucosamine, a drug preparation and a preparation method. The drug carrier based on N-acetylglucosamine comprises N-acetylglucosamine and a cross-linking agent, the cross-linking agent is a compound with an aldehyde group or a ketone group, and the aldehyde group or the ketone group reacts with the deacetylated N-acetylglucosamine to generate one or more of a hydrazide bond, a hydrazone bond or an imine bond. The drug carrier based on N-acetylglucosamine shows remarkable advantages in the aspects of particle size distribution, drug loading capacity, encapsulation efficiency and cumulative drug release rate.

The invention discloses application of a hydrazide nucleating agent containing a long alkyl chain in polyethylene glycol terephthalate, and relates to the technical field of polyethylene glycol terephthalate modification. A long alkyl chain structure in the hydrazide nucleating agent containing the long alkyl chain plays a lubricating role in a polyethylene glycol terephthalate matrix, and regular arrangement of molecular chains of the polyethylene glycol terephthalate matrix is promoted. Meanwhile, rich-NH on a molecular chain of the hydrazide nucleating agent containing the long alkyl chain can generate hydrogen bond interaction with polyethylene glycol terephthalate, so that the interface bonding force between the hydrazide nucleating agent and the polyethylene glycol terephthalate is greatly enhanced, the hydrazide nucleating agent is uniformly dispersed into the polyethylene glycol terephthalate, and the full play of the toughening effect of the hydrazide nucleating agent is ensured.

The invention discloses a polyurethane damping foam material and a preparation method thereof.The polyurethane damping foam material is prepared from a material A and a material B. The material A comprises, by mass, 10-30% of polypropylene oxide polyol, 40-60% of polypropylene oxide-ethylene oxide block copolymerized polyol, 10-30% of polymer polyol and auxiliary components such as a foaming agent and a chain extender; the material B is a mixture of diphenylmethane diisocyanate, a polyether polyol modified isocyanate prepolymer and a hydrazide modified isocyanate prepolymer, and the addition amount of the material B is 20-40% of the total mass of the material A. The preparation method comprises three steps of material A preparation, material B preparation and foaming molding. Through the synergistic effect of a specific polyol system and the modified isocyanate prepolymer, the foam material has good structural uniformity, mechanical stability, high resilience and high shock absorption and energy absorption performance, the forming process is simple, conditions are mild, and the foam material is suitable for industrial production and can be widely applied to the fields of sports protection products, shock absorption seat cushions and the like.

The invention discloses a < 131 > I labeled SNO hydrogel material and a preparation method of the < 131 > I labeled SNO hydrogel material. The hydrogel material is mainly composed of hyaluronic acid, firstly, one kind of hyaluronic acid is modified, API molecules are modified on the side chain of the hyaluronic acid, a reaction site is provided for marking of < 131 > I nuclide, meanwhile, the hyaluronic acid is subjected to oxidation treatment, the hyaluronic acid rich in aldehyde groups becomes a monomer for forming the hydrogel, the hyaluronic acid with another molecular weight is selected, and the molecular weight of the hyaluronic acid is changed into the molecular weight of the hydrogel. ADH rich in hydrazide groups is introduced into a side chain through amidation reaction, a hydrazone bond is formed through reaction of aldehyde groups and hydrazide, and the chemical bond can endow the hydrogel with injectable and self-healing characteristics. Nuclide labeling of the hydrogel is completed for the first time through a chloramine T method, the overall labeling rate reaches about 80%, the hydrogel has good stability under physiological conditions, < 131 > I is not prone to falling off from the hydrogel, and the hydrogel has a good antibacterial effect at 500 mu ci. By constructing a bacterial infection osteoarthritis model, it is verified that the < 131 > I-labeled HA hydrogel has good injectability, the in-situ enrichment capacity of iodine < 131 > I is improved, and therefore the antibacterial efficiency is improved, the method is simple in preparation, the < 131 > I labeling efficiency is high, the method can be widely applied to osteoarthritis caused by bacterial infection, and the application prospect is wide. And a wide prospect is provided for clinical treatment of the disease.

The invention relates to the technical field of 3D printing materials, and discloses 3D printing resin and a preparation method thereof. The adhesive comprises the following components in percentage by mass: 40-70% of a polyurethane acrylic resin oligomer containing a latent isocyanate group; 15%-50% of a reactive diluent; 3%-8% of a curing agent; 0.5%-10% of a photoinitiator; 0.1%-1.2% of an ultraviolet absorbent; 0.05%-0.2% of a defoaming agent; 0.5%-5% of a dispersant; 0.1%-0.5% of an antioxidant; wherein the curing agent is solid hydrazide of which the surface is modified by a surfactant. The preparation method comprises the following steps: taking a polyurethane acrylic resin oligomer containing a latent isocyanate group, adding the reactive diluent, uniformly stirring, then adding the photoinitiator, the ultraviolet absorbent and the sensitizer, uniformly stirring, then adding the dispersing agent and the curing agent, uniformly stirring, then adding the flatting agent, the defoaming agent and the antioxidant, uniformly stirring, and finally adding the curing agent, the flatting agent and the antioxidant. And finally, rolling and grinding. The 3D printing resin provided by the invention has excellent mechanical properties and long-term weather resistance, and can maintain room temperature storage stability as long as 6 months.

A multi-part aqueous coating composition comprising: water; (I) a first part comprising (a1) a core-shell latex copolymer having pendant hydroxyl groups and pendant carbonyl groups; and (II) a second part comprising (b1) at least one polyisocyanate compound having pendant-NCO groups wherein: the multi-part composition further comprises (c) at least one polyhydrazide compound having at least two hydrazide groups of the formula-C (= O)-NH-N (Rh) (Ri) wherein Rh and Ri are independently H or a C1-C12 alkyl group; the molar ratio of hydroxyl to-NCO groups in the composition is (5: 1)-(1: 5); and the molar ratio of the hydrazide group to the carbonyl group in the composition is 5: 1 to 1: 5.

The application discloses a high-temperature and high-humidity resistant polyurethane hot melt adhesive PUR and a preparation method thereof. The high-temperature and high-humidity resistant polyurethane hot melt adhesive PUR comprises the following components in parts by mass: 80-100 parts of polyether type polyurethane particles, 5-8 parts of hexagonal boron nitride nanosheets, 1-3 parts of hollow nanosilica, 3-5 parts of hydrazide-based capture agent, 1-2 parts of heat-activated microspherical epoxy resin, 0.5-1 part of zirconium aluminate, and 5-10 parts of hydrogenated terpene resin. The application utilizes multi-component synergy, simultaneously improves the high-temperature and high-humidity resistance of the polyurethane hot melt adhesive PUR, and solves the problems of softening failure of the adhesive layer caused by high temperature and molecular chain hydrolysis and peeling caused by high humidity in electronic device packaging.

The invention provides a preparation method and application of a flame-retardant-plasticizing-self-repairing polyester plasticizer for polyvinyl chloride, and belongs to the technical field of polymer functional materials and polyvinyl chloride modification. According to the method, binary acid and dihydric alcohol are used as basic raw materials, a polyester main chain is constructed through esterification and polycondensation under the action of a catalyst, and a phosphorus-nitrogen flame-retardant structural unit and a reversible disulfide bond structure are cooperatively constructed in polyester molecules by introducing a binary acid monomer containing a DOPO-hydrazide structure and 4, 4 '-diaminodiphenyl disulfide. The molecular structure of the obtained polyester plasticizer simultaneously has a flexible aliphatic chain segment, an internal flame-retardant group and a dynamic reversible covalent bond, and has good plasticizing performance, flame-retardant performance and structure reconstruction capability. When the plasticizer is blended with polyvinyl chloride resin for use, the flexibility and processability of the material can be maintained, the flame-retardant safety of the material can be improved, rearrangement and self-repairing of a microstructure can be realized under a heating condition, and the plasticizer is suitable for the field of polyvinyl chloride materials with comprehensive requirements on flame retardance, flexibility and service stability.

The invention discloses a polymeric solid electrolyte with a three-dimensional structure and a preparation method thereof, and relates to the technical field of electrochemical energy storage devices, the polymeric solid electrolyte comprises a polymer matrix and a polyurethane-hydrazide cross-linked network formed by polyethylene glycol, isophorone diisocyanate and isophthaloyl hydrazine through two-step reaction; the lithium salt is selected from at least one of lithium bis (trifluoromethanesulfonyl) imide, lithium bis (fluorosulfonyl) imide and lithium hexafluorophosphate; the functional additive comprises a combination of a halloysite nanotube and a solid electrolyte material or a nano oxide material, and the prepared solid electrolyte keeps good processability and interface contact characteristics of a polymer system by constructing a chemically crosslinked polymer three-dimensional network and synergistically compounding the chemically crosslinked polymer three-dimensional network and the uniformly dispersed inorganic functional filler. The ionic conductivity and the mechanical strength are effectively improved.