91 results about "Coordination site" patented technology

The invention relates to a unique battery having an active, porous membrane and method of making the same. More specifically the invention relates to a sealed battery system having a porous, metal oxide membrane with uniform, physicochemically functionalized ion channels capable of adjustable ionic interaction. The physicochemically-active porous membrane purports dual functions: an electronic insulator (separator) and a unidirectional ion-transporter (electrolyte). The electrochemical cell membrane is activated for the transport of ions by contiguous ion coordination sites on the interior two-dimensional surfaces of the trans-membrane unidirectional pores. The membrane material is designed to have physicochemical interaction with ions. Control of the extent of the interactions between the ions and the interior pore walls of the membrane and other materials, chemicals, or structures contained within the pores provides adjustability of the ionic conductivity of the membrane.

The invention relates to a preparation method of a ternary polymer molecular brushes heavy metal capture agent. The preparation method is characterized by comprising the following steps: dissolving 5-10 parts of ternary polymer molecular brushes in 10-50 parts of water; and stirring at 20-30 DEG C for 1-10 h to obtain a nanometer heavy metal capture agent micellar solution. The ternary polymer molecular brushes contain multi-sulfur polymer and flocculation polymer simultaneously. Each molecular chain can provide hundreds of coordination sites to carry out coordination crosslinking with heavy metal ions so as to generate micron-level aggregate. Under the action of the flocculation polymer, millimeter level and above of aggregate is rapidly generated and is rapidly deposited and separated from the water body. The generated aggregate has good stability, is not easy to decompose, and is not easy to generate secondary pollution.

PCT No. PCT / EP96 / 03888 Sec. 371 Date Mar. 11, 1998 Sec. 102(e) Date Mar. 11, 1998 PCT Filed Sep. 4, 1996 PCT Pub. No. WO97 / 10054 PCT Pub. Date Mar. 20, 1997Olefins can be epoxidized using catalysts I where M is a metal of the 4th to 7th transition group of the Periodic Table of the Elements, L1 is an amine oxide, phosphine oxide, arsine oxide, pyridine N-oxide or pyridine ligand of the formula II, III, VII or VIII, L2 is a customary auxiliary ligand or a further ligand L1 or a free coordination site, X is oxo oxygen or an imido ligand, m is 1 or 2, and n is 1, 2 or 3.

Biodegradable chelating agents comprising a substituted iminodisuccinic acid having six coordination sites and a simplified method for making same are disclosed. The method calls for mixing together an acid anhydride or lactone with a polyfunctional amine to obtain an amide which is further reacted with an amine. The chelating agents are particularly useful for agricultural applications such as fertilizers.

The invention relates to a preparation method of binary polymer molecule brush heavy metal chelating agent. The preparation method is characterized by comprising steps of dissolving 5-10 parts by weight of binary polymer molecule brush in 10-50 parts of water; stirring for 1-10 hours under 20-30 DEG C, and obtaining micellar solution of nanometer heavy metal chelating agent. The invention solves the defects that the settling effect of heavy metal ion is bad and the settlement is completed by micromolecule polysulfide; every molecular chain can provide hundreds and even thousands of coordination sites to match and crosslink with heavy metal ions, and thereby obtaining micron order to millimeter aggregation, and effectively settling and separating from water body. The generated aggregation is good in stability, not easy to decompose and generate the secondary pollution.

The invention relates to an iron / cobalt duplex-metal organic framework material as well as a preparation method and application thereof. The preparation method comprises the steps: dissolving cobalt nitrate hexahydrate, iron dichloride tetrahydrate and terephthalic acid into N,N dimethyl formamide to obtain a precursor solution; performing hydrothermal reaction on the precursor solution for 14 to27 h under the temperature of 110 to 170 DEG C; cooling, washing and drying to obtain the iron / cobalt duplex-metal organic framework material. Duplex transition metal coordination sites which are highly dispersed in the prepared iron / cobalt duplex-metal organic framework material disclosed by the invention can enhance effective contact between the iron / cobalt duplex-metal organic framework material and persulfate and can efficiently catalyze the persulfate to generate sulfate radicals; thus, persistent organic pollutants in wastewater can be removed. The iron / cobalt duplex-metal organic framework material is suitable for treating varieties of organic wastewater and has the advantages of high activity, small use amount, wide application pH range, good durability, convenience in operation and environmental friendliness and wide prospect in treating toxic and harmful organic wastewater which is difficult to biodegrade.

The invention discloses a method for removing low-concentration antibiotics in water through In-Co-contained MOFs adsorption and excitation persulphate synergism. The method comprises the steps that under the normal temperature, In-Co-contained MOFs and persulphate are added into wastewater containing antibiotics; on one hand, an inner cavity of the In-Co-contained MOFs can directly adsorb antibiotics in a water solution; on the other hand, dual-transition metal coordination sites in the In-Co-contained MOFs can remarkably improve the persulphate excitation efficiency to generate sulfate radical free radicals with the strong oxidizing property, the sulfate radical free radicals further oxidize the low-concentration antibiotics in the water solution to mineralize and degrade the antibiotics, and therefore the wastewater containing antibiotics is purified. The added In-Co-contained MOFs water solution is good in stability, easy to recycle and capable of repeatedly used. The method is low in cost, high in processing efficiency under the normal temperature and easy to implement, and has the great potential in the technical field of degradation-resistant antibiotics-contained wastewater treatment.

Biodegradable chelating agents comprising a substituted iminodisuccinic acid having six coordination sites and a simple method for making same are disclosed. The method calls for mixing together an acid anhydride or lactone with a polyfunctional amine to obtain an amide which is further reacted with an amine. The chelating agents are particularly useful for agricultural applications such as fertilizers.

The invention belongs to the technical field of environmental detection, and particularly relates to a covalent organic framework material, a preparation method thereof and application thereof in a fluorescent sensor. The covalent organic framework material (COFS-DT) is obtained by reacting monomers 2,6-dihydroxynaphthalene-1,5-dialdehyde (DHNDA) and 1,3,5-tris (4-aminophenyl) benzene (TAPB) through Schiff base reaction by a solvothermal method. The crystallinity, porosity and chemical stability of the COFS-DT are improved through O-H..N = C hydrogen bond interaction, and the COFS-DT is connected with many bidentate coordination sites interacting with target ions. Compared with the monomers, the COFS-DT shows stronger fluorescence when dispersed in isopropanol. The strong fluorescence and the bidentate coordination sites enable the COFS-DT to be used to construct a high-performance fluorescence sensor with high sensitivity, high selectivity and high stability for detecting Cu<2+>.

The invention discloses an azacyclic transition metal zinc complex containing multiple coordination sites, and a preparation method and application of the azacyclic transition metal zinc complex. The azacyclic transition metal zinc complex is a 1-(benzotriazole-1-methyl)-1-(2-ethyl imidazole) zinc complex, and has a molecular formula of [Zn (SCN) 2(C12H13N5)2]. The azacyclic transition metal zinc complex, namely, the 1-(benzotriazole-1-methyl)-1-(2-ethyl imidazole) zinc complex provided by the invention has a higher inhibiting effect for alpha-amylase, and the inhibiting effect of the 1-(benzotriazole-1-methyl)-1-(2-ethyl imidazole) zinc complex is much higher than that of singly-used 1-(benzotriazole-1-methyl)-1-(2-ethyl imidazole) or transition metal salt for the alpha-amylase and is higher than that of commonly-used hypoglycemic agent acarbose for the alpha-amylase. Therefore, the azacyclic transition metal zinc complex is proved to have a good hypoglycemic effect so as to be effectively used for preparing medicines for treating diabetes mellitus, and is an innovation in the aspect of medicines for treating the diabetes mellitus.

The invention provides a quinoline thiosemicarbazone-copper pyridine complex and a preparation method and application thereof. The structural formula of the copper complex is shown in the formula I orthe formula II which is shown in the description. Thiosemicarbazide, quinoline and pyridine groups are combined, a new compound has multiple advantages of thiosemicarbazide, quinoline and pyridine and has coordination sites formed by drug effect groups of different types, and the coordination selectivity and diversity of the compound are improved. A ligand is bonded with metal ions to form the complex, and the double advantages of a metal center and an organic compound are presented. Through diversified coordination modes of the ligand and the formed complex with a specific structure, the specific biological activity is generated. The copper complex formed by human endogenous metal copper has the biological activity and expresses extremely high activity of resisting tumor cell proliferation.

The invention relates to a homogeneous time resolved fluorescence immunoassay chelating agent and the preparation method thereof. The chelating agent is N, N, N', N'-((2, 6-di(3'-aminomethyl)-1-pyrazole)-4-(4-isothiocyanate(phenylacetylene)-pyridine))-tetraacetic acid. A luminous group is 2, 6-di(pyrazole) pyridine; the invention has high triplet-state energy level, the excitation wavelength after the combination with rare earth ions is 320nm, the emission wavelength is 520 to 620nm, the luminous service life is 2.99ms, the quantum yield is 0.58, the invention is in line with the requirements of homogeneous TRFIA to be combined with phenylacetylene at the pyridine 4-position, and the acetylene bond can block protein macromolecules from consuming luminous energy. The phenyl 4-linking isothiocyanate at the pyridine 4-position can be coupled with protein without injury, so as to be conductive to the high-efficient measurement of the luminescence of the chelating agent. The polyammonia polycarboxyl structure of 11 coordination site can exclude the quenching function of water molecules on rare earth luminescence and improve the solubility of the chelating agent in water and the dynamic stability of the chelating agent in the water r solution.

An adsorbate-selective metal organic framework includes a transition metal; and a plurality of organic molecules coordinated to the transition metal so as to preserve open coordination sites for selectively adsorbing molecules that have low-lying π* orbitals. The transition metal has a lowest energy spin state in the presence of the selectively adsorbed molecules that are strongly bonding to the transition metal through π-donating interactions which is different than the lowest energy spin state in the absence of these adsorbed molecules. The transition metal has also a lowest energy spin state in the presence of non-selected molecules that are weakly bonding to the transition metal through σ- and / or π-accepting and / or donating interactions.

The invention relates to a nickel magnetic microsphere and a preparation method and an application thereof. A magnetic silicon dioxide microsphere is prepared by adopting a sol-gel method, wherein themagnetic silicon dioxide microsphere takes magnetic substrate particles as a core, takes tetraethoxysilane as a silicon source and forms a shell through a reaction; the microsphere, used as a template, is modified by epoxy silane coupling agent KH-560 and iminodiacetic acid to form a ligand which is used as a complexing agent for chelating metal nickel ions to prepare the magnetic silicon dioxidemicrosphere with chelated nickel ions on the surface. By adopting the iminodiacetic acid modified silicon dioxide microsphere, multiple coordination sites can be provided for metal nickel ions, so that relatively high acting force between the modified microspheres and the metal nickel ion can be ensured, and the unsaturated coordination sites of metal ions can be acted with protein, thereby realizing that the magnetic silicon dioxide microsphere with chelated nickel ions on the surface can separate protein from a solution.

A charge-neutral organometallic dendrimer is described, said dendrimer having the formula (I):CORE-[DENDRITE(-Q)a]n  (I)in which CORE represents a group of formula MXxYz, in which M represents a metal cation, x represents an integer of 1 or more, each X which may be the same or different represents a mono-, bi- or tri-dentate coordinating group, z represents 0 or an integer of 1 or more, and each Y which may be the same or different represents a coordinating group, the total of (b.x)+(c.z) being equal to the number of coordination sites on M, wherein b is the number of coordination sites on X and c is the number of coordination sites on Y; n represents an integer of 2 or more; each DENDRITE which may be the same or different represents a dendritic molecular structure bonded to a group X; a represents 0 or an integer of 1 or more; and each Q which may be the same or different represents a surface group; CORE terminating in the first single bond which is connected to a branching group or branching atom of DENDRITE; which dendrimer has a structure in which no hemisphere of a notional sphere centred on M and containing the dendrimer is devoid of a said first single bond.

The invention discloses an amphipathic nano-micelle with a POSS (Polyhedral Oligomeric Silsesquioxane) based capping end sensitive to metal ions and a preparation method of the amphipathic nano-micelle. POSS serves as a lyophobic end of an amphipathic macromolecule; the tail end of a hydrophilic chain is subjected to functional modification; 2,6-pyridinedicarboxylic acid is introduced as a coordination site; modified PEG (Polyethylene Glycol) has certain responsivity to the metal ions; the amphipathic molecule of the micelle is sensitive to the metal ions; the micelle is in a metastable state structure in a selective solvent; when the metal ion concentration in a surrounding environment is changed, the assemble form and volume of the micelle are changed quickly and significantly; and the micelle has potential application values in medicine loading, release controlling, molecule sensors and other aspects.

A titano-silico-aluminophosphate which contains tetrahedrally coordinated titanium in the framework structure, which has a free coordination site for CO which can be detected by means of a characteristic IR band at 2192±5 cm−1. The titano-silico-aluminophosphate has extremely high hydrothermal stability and has a good adsorption capacity even at higher temperatures. Also, a hydrothermal method to obtain a titano-silico-aluminophosphate starting from a synthetic gel mixture of an aluminium, phosphorus, silicon and a titanium source, as well as corresponding templates.

Organic polymeric multi-metallic alkoxide or aryloxide composites are used as dielectric materials in various devices with improved properties such as improved mobility. These composites comprise an organic polymer comprising metal coordination sites, and multi-metallic alkoxide or aryloxide molecules that are coordinated with the organic polymer, the multi-metallic alkoxide or aryloxide molecules being represented by:(M)n(OR)x wherein at least one M is a metal selected from Group 2 of the Periodic Table and at least one other M is a metal selected from any of Groups 3 to 12 and Rows 4 and 5 of the Periodic Table, n is an integer of at least 2, R represents the same or different alkyl or aryl groups, and x is an integer of at least 2.

The invention relates to a chlortetracycline (CTC) molecularly imprinted (MIP) affinity membrane sensor and a preparation method thereof. The specific affinity membrane is formed based on an electropolymerization method, and CTC as a template molecule and o-aminophenol (OAP) as a functional monomer form a molecularly imprinted polymer membrane on the surface of a glassy carbon electrode by an electrochemistry method. CTC contains a phenolic hydroxyl group, an enol group and a dimethylamino group and the hydroxyl group in the OAP structure can be used as a latent coordination site so that OAP amino group, and phenolic hydroxyl group and enol group of CTC undergo intermolecular hydrogen bond interaction. OAP hydroxyl group and CTC dimethylamino group undergo a reaction so that multiple binding sites between OAP and CTC exist and the prepared molecularly imprinted polymer has very high CTC selectivity and bonding capability. The sensor can be used for on-site fast detection, does not need specimen pre-treatment, and has a low cost, simple processes and high sensitivity. The sensor has a detection linear range of 20-610nM and sensitivity of 15nM.

A multidentate ligand includes at least two planar tetradentate coordination sites in one plane, each of the planar tetradentate coordination sites containing four nitrogen-containing groups of at least one of imino, amido and amino groups, and has the nitrogen atoms of the four nitrogen-containing groups as coordinating atoms in one plane. A metal complex assembly has one of two-dimensional and three-dimensional structures and contains metal complex chains and electroconductive wires, the metal complex chains each contain assembled metal complexes, the electroconductive wires each contain molecules serving as at least one of an acceptor and a donor, and the metal complex chains intersect with the electroconductive wires at such positions that the metal complexes and the molecules serving as at least one of an acceptor and a donor are capable of interacting with each other.

The invention relates to a diagnosis and treatment integrated bovine serum albumin anticancer nanoparticle and a preparation method thereof. The particle comprises bovine serum albumin, rare earth metal ion and anticancer drug, wherein the rare earth metal ion and bovine serum albumin form nanoparticle with imaging function through coordination, the anticancer drug is immobilized on the nanoparticle and is bound to the rare earth metal ion coordination site that interacts with bovine serum albumin. Compared with the prior art, according to the invention, bovine serum albumin solution with certain concentration and rare earth metal ion solution form a compound particle through coordination. The structure and morphology of the compound particle can be regulated by changing the concentration of the two solutions to improve the particle performance. In addition, an element (rare earth metal ion) with MRI effect is introduced at the coordination site of the system. Compared with the traditional nanoparticle, the preparation method has the advantages of flexible and easily controllable regulation, and good repetitiveness, and the obtained nanoparticle has excellent properties.

The invention belongs to the field of environmental protection and specifically relates to a preparation method of heavy metal ion-adsorbed high polymer material modified adsorbent resin and adsorption performance thereof. The preparation process comprises the following steps: synthesizing polyaniline, synthesizing diglycerol acyl chloride, and grafting the diglycerol acyl chloride on the polyaniline. The polyaniline is generally applied to a conductive material, a sensor, and the like, and not applied to the environmental protection field. The invention discloses a preparation technology of modified polyaniline chelate resin with multiple coordination sites, wherein material resource is wide, operation steps are simple, reaction conditions are gentle, and removing effect on metal ion Cu<2+> is over 90%.

Organic polymeric multi-metallic alkoxide or aryloxide composites are used as dielectric materials in various devices with improved properties such as improved mobility. These composites comprise an organic polymer comprising metal coordination sites, and multi-metallic alkoxide or aryloxide molecules that are coordinated with the organic polymer, the multi-metallic alkoxide or aryloxide molecules being represented by:(M)n(OR)x wherein at least one M is a metal selected from Group 2 of the Periodic Table and at least one other M is a metal selected from any of Groups 3 to 12 and Rows 4 and 5 of the Periodic Table, n is an integer of at least 2, R represents the same or different alkyl or aryl groups, and x is an integer of at least 2.

The invention belongs to the field of the paramagnetic labeling of the proteins, and provides a DTPA (Diethylene Triamine Pentacetic Acid) analogue for paramagnetic labeling of proteins. The DTPA analogue with eight coordination sites is a mercaptopyridine activated paramagnetic label and can be directly used for labeling the connection of protein and protein; if lanthanide series metal ions are added dropwise to the DTPA analogue, the DTPA analogue is capable of generating huge pseudocontact shifts and residual dipolar couplings and thus can be still used even at a low pH.

The present invention is generally directed to a method of prophylaxis against viral infection of a cell or subject or a method of treating a subject infected with a virus including administering an antiviral composition having the general Structure III,wherein each of R1, R2, R3, R4, R5 and R6 is the same or different and includes an N-based ligand donor atom selected from the group consisting of ammonia, primary amine or secondary amine, or salt thereof. The present invention is also generally directed to a method of preparing an antiviral agent including providing a cobalt pentammine salt having a non-amine coordination site and mono-substituting the non-amine coordination site with a functional group incorporating a strong coordinator atom to cobalt to form a CoHex structure of Structure III, in which R1 incorporates the functional group having the strong coordinator atom coordinated with the cobalt atom, or a salt thereof.

The invention relates to a chiral paramagnetic probe using 1,4,7,10-tetraazacyclododecane as a skeleton. The chiral paramagnetic probe has the chemical name of 1,4,7,10-tetraazacyclododecane-1-(2-methyl-4-phenylsulfonyl-6-methylene)pyridine-2,3,4-tri(S)-propionic acid anion-Tm3 + complex, the chemical formula of C30H40N5O8STm, and the chemical structural formula as shown in the description. The chiral paramagnetic probe provided by the invention has the advantages of 1) specific chirality, single conformation, only a set of peaks in a spectrogram and high sensitivity; 2) high chemical selectivity; 3) electric neutrality and small impact on macromolecules; 4) good water solubility, more coordination sites, strong stability and high denticity; 5) extremely strong rigidity and good fixation effect on macromolecules; 6) performing of intracellular measurement due to the connection between the probe and a protein through stable thioether bonds. The advantages have an important promotion effect of the chiral paramagnetic probe on the paramagnetic study of proteins.

The invention relates to the technical field of supramolecular recognition, and discloses a preparation method and application of a constructed metal-organic limited domain structure based on a flexible ligand. Ce3+, Eu3+ or Tb3+ which are provided with certain coordination modes in rare earth metal salt are taken as nodes, and a metal-organic clathrate compound of a flexible limited domain cavitystructure is prepared by regulating and controlling the proportion of coordination sites to metal nodes in the ligand and utilizing a poor solvent diffusion method or layering diffusion method. Flexible functional groups are introduced in the target material to strengthen the interaction effect between limited range host molecules and guest small molecules, can show adaptive ability similar to 'abreath effect' in the supramolecular interaction process, and can show excellent selective recognition on natural small molecules with similar structures and sizes. Compared with the prior art, the method has the advantages of good adaptability, high supramolecular interaction, high concentrated selectivity, convenient visual detection and the like and has a better application prospect in the fields of molecular recognition, fluorescence probes and the like.

Provided are a near-infrared-ray-absorbing composition having strong near-infrared shielding properties when a cured film is produced, a near-infrared-ray cut filter, a manufacturing method therefor, a camera module, and a manufacturing method therefor. The near-infrared-ray-absorbing composition includes a copper complex obtained by reacting a compound (A) having at least two coordination sites with a copper component.

The invention relates to a kaoline-2-pyrazine carboxylic acid intercalation compound and a preparation method thereof. The preparation method comprises steps as follows: 1) natural kaoline soil is subjected to ultrasonic cleaning for 0.5 h, and washed kaoline is obtained; 2) the washed kaoline and dimethyl sulfoxide are stirred for 12 h at the room temperature, and a precursor is prepared; 3) the precursor and 2-pyrazine carboxylic acid (in the mass ratio being 1:1) are put in a stainless steel reaction kettle, intercalation is performed under increased pressure, and the mixture reacts for 5-10 h at the temperature of 90-160 DEG C; 4) a target product is obtained through alkali liquor washing, centrifugation and drying and has a chemical formula Al2Si2O5(OH)4.(2-PA)1.11, and 2-PA is 2-pyrazine carboxylic acid. The compound has a two-dimensional lamellar structure, and interlayer 2-pyrazine carboxylic acid molecules have N,O activity coordination sites and can be applied as potential optical, electric and dielectric materials. The kaoline-2-pyrazine carboxylic acid intercalation compound adopts a simple process and is convenient to prepare.

This invention relates to a Cu-BTC MOF which is water stable. The Cu-BTC MOF has open coordination sites and has been post synthesis modified by partially occupying the open sites with a ligand such as acetonitrile (CH3CN). The resultant MOF retains at least 40% of its as synthesized surface area after exposure to liquid water at 60° C. for 6 hours. This is an unexpected result versus the MOF which has not been post treated with ligands such as acetonitrile. This MOF can be used to abate contaminants such as ammonia in gas streams and especially air streams.