118 results about "Nasal cavity" patented technology

An apparatus includes a body, a shaft assembly, and a visualization assembly. The body includes first and second actuators. The shaft assembly extends distally from the body and includes a rigid proximal portion and a steerable distal portion. The steerable distal portion is positioned distally relative to the rigid proximal portion. The first actuator is operable to drive the steerable distal portion to deflect laterally relative to a longitudinal axis defined by the rigid proximal portion. The steerable distal portion is configured to fit within a nasal cavity of a patient. The visualization assembly is disposed within the shaft assembly. The visualization assembly includes a camera. The second actuator is operable to drive longitudinal translation of the visualization assembly relative to the shaft assembly.

The present application relates to a kind of respiratory synchronous diaphragm nerve electric stimulator in vitro, belong to medical equipment technical field.The technical scheme of a kind of diaphragm nerve electric stimulation based on real-time breathing signal synchronization trigger is proposed for the problems of high weaning failure rate and quality of life decline caused by VIDD.The technical scheme points include: detecting inspiration negative pressure signal through nasal cavity air pressure sampling tube, control unit dynamically adjusts trigger threshold according to negative pressure signal, when negative pressure is lower than preset value and waveform slope meets the standard, trigger electric stimulation module to output biphasic pulse, pulse parameters include positive and negative alternating waveform, width 0.1ms to 1ms, frequency 10Hz to 50Hz and current intensity 5mA to 30mA, and strictly limit electric stimulation to be only output in inspiration cycle, and expiration cycle is completely blocked stimulation by hardware switch circuit.It is mainly suitable for intensive care and rehabilitation therapy scene, effectively prevent and treat VIDD, improve patient weaning success rate and quality of life.

The invention provides a nasal delivery preparation for cerebral diseases as well as a preparation method and application of the nasal delivery preparation, and relates to the technical field of pharmaceutical preparations. The nasal delivery preparation for the cerebral diseases comprises gelatin derivative chitosan microspheres coated with stem cell exosomes, and the microspheres are prepared through the method that the stem cell exosomes are coated with gelatin derivatives of a specific structure and then cross-linked with chitosan. The gelatin derivative used in the invention has good surface activity, and can be well compatible with cells and active factors to form a stable inner core coating structure; meanwhile, the surface of the chitosan of which the outer layer is crosslinked with the gelatin derivative is positively charged and can be combined with anions in nasal mucus, so that the retention time of the microspheres in the nasal cavity can be effectively prolonged. Therefore, the nasal delivery preparation not only can slowly release the stem cell exosome, but also improves the absorption efficiency of the stem cell exosome by the nasal cavity, so that the stem cell exosome can reach the brain more effectively.

The invention discloses a novel atomization dosing instrument, and relates to the technical field of atomizers. The device comprises a main body, the main body comprises a main body outer shell and a main body upper shell which are connected with each other, an internal support is installed on the main body outer shell, and an electrical assembly is installed on the internal support. When the electronic cigarette is used, the key is installed on the main body shell, the key is connected with the atomizing element so that the atomizing element can be started or stopped, and the electrical assembly is arranged between the main body shell and the main body upper shell; through the control of the electrical assembly, the device can atomize liquid medicine in an electronic atomization mode, and the problem that a traditional atomizer needs to be pressed with large force is solved; the waste is reduced by accurately controlling the dosage of the liquid medicine; the atomizing head does not enter the oral cavity and the nasal cavity for administration, so that the administration experience is very comfortable; the diameters of atomized particles are adjusted by matching different liquid medicines with different atomizers, so that the liquid medicines can better reach affected parts.

A hydrogel composition for intranasal delivery of an antifungal (amphotericin B) at an infection site, specifically the nasal mucosa and upper respiratory tract.

The invention discloses breathing assisting equipment for heart failure patients, and relates to the technical field of medical instruments, the breathing assisting equipment comprises straps, an extrusion mechanism is fixedly connected to the outer surface of the straps, a breathing mechanism is fixedly connected to the outer surface of the extrusion mechanism, and an electric rod is utilized to extrude a breathing air bag, so that the breathing air bag can be inflated; oxygen in the breathing air bag can be extruded out, and the soft plate is made of a soft material, so that the breathing air bag cannot be damaged. And traditional manual labor can be effectively replaced through the telescopic effect of the electric rod, the automation effect is achieved, and the labor intensity of workers is relieved. Oxygen is primarily infiltrated through wetting cotton in the arc-shaped box, so that the wettability of the respiratory tract of the patient can be enhanced, and the inner surface of the nasal cavity of the patient is protected. Meanwhile, the two moving boxes can be driven to slide through rotation of the screw rod, the distance between the two nose plugs can be conveniently adjusted, the nasal plug fixing device can adapt to different crowds, and then the comfort degree of the patient using the nose plugs is improved.

An acoustic face mask reduces the distortion and muffling of speech sounds by a face mask wall. The distortion and muffling of speech sounds by a face mask wall may be reduced by reducing the acoustic coupling of the vocal tract and / or nasal cavity to the face mask chamber, which causes a reduction in the intelligibility of the speech. The acoustic coupling of the vocal tract and / or nasal cavity to the face mask chamber may be reduced, for example, by reducing the reflected sound energy caused by the face mask wall. For example, one or more sound absorbing members or acoustically transparent members reduce the reflected sound energy caused by the face mask wall.

1. The present invention discloses a cushion assembly for a patient interface, the cushion assembly comprising: a plenum chamber pressurisable to a therapeutic pressure of at least 6cmH2O above ambient air pressure, said plenum chamber including a plenum chamber inlet port, said plenum chamber inlet port being sized and structured to receive a flow of air at the therapeutic pressure for breathing by a patient; and a sealing structure constructed and arranged to have a shape to form a seal with a region of the patient's face surrounding an entrance to the patient's airways such that the flow of air at said therapeutic pressure is delivered to at least an entrance to the patient's nares, said seal being formed to prevent air exiting from the plenum chamber between the sealing structure and said region of the patient's face, the sealing structure structured and arranged to maintain said therapeutic pressure in the plenum chamber throughout the patient's respiratory cycle in use; wherein the sealing structure comprises a sealing surface to form the seal against the patient's face in use, and wherein the sealing structure comprises a tie that extends between a first interior surface region of the sealing structure that is opposite the sealing surface and a second interior surface region of the patient interface such that the tie resists deformation of the sealing structure to prevent blowout.

The invention describes a method including the administration of a pharmaceutical composition. The administration includes dispensing a pharmaceutical filler composition comprising an active agent from a soft gel capsule into a patient's nasal cavity for nasal absorption or into the patient's oral cavity for pregastric absorption.

The utility model relates to the technical field of oxygen therapy nasal plugs, and discloses an anti-falling oxygen therapy nasal plug for senile cardiology heart failure patients, which comprises a connecting tube and a nasal plug tube, oxygen delivery tubes are mounted on two sides of the connecting tube, and branch tubes are arranged at the top ends of the oxygen delivery tubes. According to the anti-falling oxygen therapy nasal plug for the senile cardiology heart failure patient, the elastic hanging rope is arranged, the sliding sleeve slides outside the oxygen delivery pipe to adjust the position of the elastic hanging rope, and after the elastic hanging rope is adjusted to the proper position, the elastic hanging rope can be hung on the ear of the patient; the oxygen delivery pipe is limited to prevent the nasal plug pipe and the nose plug on the connecting pipe from accidentally falling off from the nasal cavity of a patient, the limiting sleeve is pulled to slide at the top end of the outer portion of the oxygen delivery pipe through the reserved groove, and therefore the oxygen delivery pipe can be further limited, and the problem that the nasal plug pipe and the nose plug are prone to falling off from the nasal cavity of the patient is solved. And hidden dangers are easy to increase.

The invention discloses a controllable endoscope for nasopharyngeal carcinoma postoperative rehabilitation examination, and belongs to the technical field of endoscopes, the controllable endoscope comprises an endoscopic examination tube, a lens bearing part, a lens part, a sealing assembly, a pushing assembly and an angle adjusting assembly.When the controllable endoscope is used, a sealing air pump inflates a transparent sealing air bag, the pushing air bag is in an uninflated state, and the angle adjusting assembly is used for adjusting the angle of the lens part; when the endoscopic examination tube is inserted into one end of a nasal cavity and reaches an operation part, the sealing air pump deflates the transparent sealing air bag, the pushing air pump inflates the pushing air bag, so that the end of the lens part moves out of the inner cavity through the opening, and then the deflection air bag part moves out of the inner cavity through the deflection air pump part under the action of the deflection air pump part. The deflection angle of the lens part is adjusted, so that multi-angle examination can be carried out on the surgical site and the periphery, a basis is provided for an examiner to accurately judge the rehabilitation condition, the operation convenience of the examiner is improved, the frequency of adjusting the position of the endoscope is reduced, and the discomfort of a patient and the possibility of secondary injury are reduced.

A respiratory system for providing respiratory support to a patient, the system comprising: a nasal interface and a gas conduit for delivering a flow of gases to an outlet of the nasal interface, and a flow controller for selectively controlling the flow of gas into nasal interface, the flow controller configured to operate when a pressure in the system is above a predetermined value to restrict or prevent the flow of gas into the nasal interface from the gas conduit.

The present application relates to the technical field of sleep intervention, in particular to an intelligent sleep instrument and a sleep instrument control method, the system comprising a respiratory mutation recognition module, a slow wave initiation linkage module, a pharyngeal cavity contraction evaluation module, an intervention section positioning module and a delay trigger control module. In the present application, the extreme points densely appearing in the continuous cycle are accurately positioned as the key nodes of respiratory abnormalities through the identification of the mutation of nasal respiratory flow, and the slow wave initiation stage closely related to the respiratory mutation is screened out and marked as the linkage period in combination with the power curve change trend of the electroencephalogram signal. The pharyngeal cavity state is dynamically evaluated through the change of acoustic echo in the period, the intelligent postponement and delay processing of the intervention behavior are realized through the comparison of the trigger point of the intervention action and the boundary of the platform section, the accuracy of the sleep intervention timeliness and the adaptability of the intervention execution are improved, and the respiratory event control effect and the sleep continuity are significantly improved.

The invention discloses a nasal cavity coated drug-loaded stent and a preparation method thereof, and relates to the technical field of nasal cavity stents.The coated drug-loaded stent comprises a coated drug-loaded stent body and a drug coating covering the surface of the coated stent body, and the drug coating comprises a therapeutic drug and a carrier thereof; the carrier comprises a first polymer and a second polymer which have different drug loading functions; and a tissue regeneration guide layer can also be arranged on the medicine coating. The coated drug-loaded stent provided by the invention not only has a large wound surface contact area, but also can effectively regulate and control the drug release period, so that the drug release during the wound surface repair period is more stable, long-acting and controllable, thereby meeting the needs of nasal cavity wound surface repair.

The invention provides an auxiliary nasal cavity flusher for nasopharyngeal carcinoma treatment and a flushing fluid formula, and belongs to the technical field of medical instruments.The auxiliary nasal cavity flusher for nasopharyngeal carcinoma treatment comprises a connecting shell, and a liquid medicine mixing device, a liquid medicine distributing device, a liquid medicine collecting box and a flushing fluid collecting box are installed on the inner wall of the bottom of the connecting shell; the liquid medicine mixing device, the liquid medicine flow dividing device, the liquid medicine collecting box and the flushing liquid collecting box are connected through pipelines, a microprocessor and a sensor array are arranged in the intelligent integrated controller, the temperature and flow of flushing liquid and the liquid medicine mixing proportion can be monitored in real time, and it is ensured that treatment conditions are optimized; a user or an intelligent system can adjust the flushing speed and total amount through the controller, the treatment effect is guaranteed, unnecessary stimulation is reduced, and the flushing comfort level is improved.

The invention provides a traditional Chinese medicine preparation for treating or improving chronic rhinitis, and relates to the field of traditional Chinese medicine pharmacy, and the traditional Chinese medicine preparation comprises patrinia, herba siegesbeckiae, Japanese metaplexis pericarp, oroxylum indicum, adenophora stricta, radix ophiopogonis, radix polygonati officinalis, rhizoma sparganii, fructus kochiae, schizonepeta, cortex dictamni, cortex lycii radicis and salvia chinensis. The traditional Chinese medicine preparation can effectively inhibit LPS-induced excessive inflammatory response of HNEpC, also can significantly reduce VAS score, SNOT-20 score and nasal endoscopic Lund-Kenne score of chronic rhinitis patients, effectively relieves core symptoms such as nasal obstruction, running nose and hypoolfaction, relieves negative effects of diseases on sleep, emotion and daily activities of the patients, relieves nasal mucosa edema, reduces abnormal secretions, and has a good treatment effect on chronic rhinitis. The repair of damaged mucosa is promoted, and the organic lesion of the nasal cavity is effectively improved. The traditional Chinese medicine preparation has high total clinical treatment rate, provides a better and safer new scheme for clinical treatment of chronic rhinitis, and has important clinical application value.

The present disclosure relates to an adenoid stent and an adenoid support assembly. The adenoid stent includes: a tubular support portion for supporting in the nasal passage; a first expansion support portion for supporting at the anterior nostril, the first expansion support portion being provided at the first end of the tubular support portion and expanding radially outward relative to the tubular support portion; and a second expansion support portion for pressing the adenoid against the posterior wall of the nasopharynx, the second expansion support portion being provided at the second end of the tubular support portion opposite to the first end and expanding radially outward relative to the tubular support portion; wherein the first expansion support portion, the second expansion support portion and the tubular support portion are coaxially arranged, and the first expansion support portion, the second expansion support portion and the tubular support portion are configured as a mesh structure capable of radially telescoping. Through the above technical solution, the adenoid stent and the adenoid support assembly provided by the present disclosure can solve the technical problem of being unable to balance the support of the adenoid and the ventilation of the nasal airway.

An air extraction device and a nasal aspirator. The air extraction device includes a cylinder body and a variable-volume body. The cylinder body defines a cavity and a first air hole, and the first air hole is in communication with the cavity. The variable-volume body is arranged within the cavity. The variable-volume body is configured such that, through a change in a volume of the variable-volume body within the cavity from large to small, an air pressure within the cavity is reduced, for providing a suction force externally through the first air hole.

The invention generally relates to systems and methods for targeting of specific tissue(s) of interest in a sino-nasal region of a patient for the treatment of a rhinosinusitis condition. A device of the present invention includes an end effector comprised of one or more segments, each segment comprising one or more struts which can be in the form of loop-shaped struts or independent struts and each comprising a flexible printed circuit board (PCB) member for delivering energy to one or more target sites within the sino-nasal cavity of the patient while minimizing or avoiding collateral damage to surrounding or adjacent non-targeted tissue, such as blood vessels, bone, and non-targeted neural tissue.

The utility model provides a binding elastic retaining cap suitable for puncture intervention post-operation, which relates to the technical field of post-operation binding tools and comprises a retaining cap body, a connecting band a connected to one end of the retaining cap body in a sewing manner, a connecting band b connected to the other end of the retaining cap body in a sewing manner and a fixing component arranged between the connecting band a and the retaining cap body and between the connecting band b and the retaining cap body. The fixing assembly is used for fixing, pressurizing and bandaging the head of a child patient and comprises an opening, a hook-and-loop fastener a and a hook-and-loop fastener b. The pressure bandaging position of the head of a child patient can be tightly wrapped through the head sleeve body, the head sleeve body is fixed to the head of the child patient through the fixing assembly, the good supporting and fixing effects can be achieved when pressure bandaging is needed for special parts such as ear backs, jaw backs and head tops, and the stability of the fixing mode of the head sleeve is good; the problems that an existing elastic bandage is prone to loosening and slipping, the nasal cavity of a child patient is prone to being blocked, breathing of the child patient is affected, and postoperative recovery of the child patient is affected are solved.

The utility model belongs to the field of tooth correctors, and particularly provides a wearing indicating device for a tooth corrector, the wearing indicating device comprises a shell, and a sensor module, a control module and a power supply module which are arranged in the shell, the shell comprises a limiting part, a containing part and a boss, and the limiting part is used for being connected with the tooth corrector; a signal reinforcing structure communicated with the atmosphere is arranged in the boss, and when the wearing indicating device is connected with the tooth appliance for use, a port of the signal reinforcing structure faces a nasal cavity and is used for transmitting and amplifying a signal from the nasal cavity; the sensor module is located in the signal reinforcing structure and used for collecting signals amplified by the signal reinforcing structure. The wearing indicating device provided by the utility model can accurately judge the wearing condition of the tooth appliance by analyzing the signal from the nasal cavity.

The invention discloses a traditional Chinese medicine composition and application thereof in preparation of medicine for treating obstructive sleep apnea hypopnea syndrome, and the traditional Chinese medicine composition comprises the following raw materials in parts by mass: 6 parts of rhizoma acori graminei, 6 parts of agastache rugosus, 6 parts of radix angelicae, 6 parts of bamboo shavings, 6 parts of ligusticum wallichii, 3 parts of mint and 1.5 parts of borneol. Research finds that the traditional Chinese medicine composition has the effects of inducing resuscitation, inducing resuscitation and resolving dampness with aromatics, can remarkably improve clinical symptoms (including fatigue, sleepiness, headache in the morning, awakening at night, dry mouth, amnesia, low emotion and the like) of OSAHS patients (especially moderate and severe patients), remarkably reduces the peripheral blood CRP level of the OSAHS patients (especially moderate and severe patients) and the CRP and IL-6 level in nasal cavity flushing fluid, and has the advantages of being free of toxic and side effects, free of toxic and side effects and the like. The inflammation reaction of the upper respiratory tract and the life quality of patients are improved. And a safe, effective, easy-to-implement and more easily accepted way for the improvement of OSAHS is provided.

Described herein are devices, systems, and methods for applying a tension force to various tissues. The devices may be delivered in a minimally invasive fashion and used to manipulate tissues in the nose (e.g., nasal septum, nasal turbinates), ear, and throat. Force may be maintained by the devices for a time period that allows shaping, compression, and / or approximation of tissues.

The application discloses a recombinant adenovirus vector tumor vaccine and a preparation method and application thereof, wherein the antigen coded by the recombinant adenovirus vector tumor vaccine comprises any one or a combination of more than two antigen peptide epitopes of KRAS protein. The recombinant adenovirus vector tumor vaccine of the application codes multiple KRAS tumor-specific antigen peptides, and has a good killing effect on KRAS mutation-driven tumors, especially lung tumors. The vaccine can be inhaled in a form of atomization, injected into muscles first and then inhaled in a form of atomization, inhaled in a form of atomization first and then injected into muscles, injected into muscles, or simultaneously injected into muscles and administered in a form of atomization. After atomization, the vaccine can be inhaled through a nasal cavity or an oral cavity to reach the lungs, generate an anti-tumor protective immune response on the respiratory tract, the lungs and the whole body, and enhance the utilization rate and the treatment effect of the vaccine.

Doxycycline injections improve the appearance of cosmetically significant lower eyelid festoons and malar edema, as well as of the jowls. The doxycycline is also useful for reducing edema of turbinates, the nasal concha or conchae shell-shaped networks of bones, vessels, and tissue within the nasal passageways that are responsible for warming, humidifying, and filtering the air as it is inhaled. The doxycline, in a concentration preferably of greater than 10 to 20 mg / ml, preferably in combination with a local anesthetic and optionally with a vasoconstrictor such as epinephrine and a pH buffering agent, is injected into the subcuticular space at the site of swelling. The high viscosity limits the spread of the doxycycline to the area to be treated. The resulting sclerosis prevents fluid accumulation. The doxycline also decreases swelling due to fat, by causing a decrease in lipomas.

The utility model is suitable for the technical field of sleep respiration monitoring equipment, and provides sleep respiration monitoring equipment which comprises a head and face mask part and a respiration monitoring part, the head and face mask part comprises a head cover assembly and a face mask assembly, and a wearing space can be formed between the head cover assembly and the face mask assembly; the respiration monitoring part comprises a pressure monitoring assembly and a temperature monitoring assembly, the pressure monitoring assembly is arranged on the head and face mask part and comprises an airflow catheter and a pressure sensor, and the input end of the airflow catheter can be arranged in the nasal cavity in a penetrating mode; the monitoring end of the temperature monitoring assembly is arranged in the airflow guide pipe and corresponds to the input end of the airflow guide pipe in position. According to the sleep respiration monitoring equipment, through structural multiplexing of the monitoring end of the temperature detection assembly and the input end of the airflow guide pipe, the occupied space of the monitoring end of the temperature detection assembly and the input end of the airflow guide pipe in the nasal cavity of a patient is reduced, and the use experience of the patient is improved.

The invention relates to chitosan-containing nasal anti-allergic powder and a preparation method thereof, belongs to the technical field of medicines, and solves the problem that a barrier film formed by an existing nasal anti-allergic product is relatively short in residence time in a nasal cavity. The nasal antiallergic powder is prepared from modified chitosan containing-NH3 < + >, carboxymethyl chitosan, a soothing agent and a preservative, the anti-allergic powder for the nose is prepared from the following components in parts by weight: 30 to 70 parts of modified chitosan containing-NH < 3 + >, 30 to 50 parts of carboxymethyl chitosan, 0.1 to 2 parts of a soothing agent and 0.0001 to 0.1 part of a preservative. The nasal antiallergic powder can stay in a nasal cavity for a long time, and can instantly expand to form a film when being in contact with the moist nasal cavity.

The utility model provides a nasal cavity enteral nutrition tube which comprises a nutrition tube body and a heating box used for wrapping the nutrition tube body, the heating box comprises a box body and a box cover, and the box cover is arranged on the box body in a detachable mode. A supporting table is arranged in the box body, the supporting table is of a vortex line structure, a groove is formed in the top face of the supporting table, and the groove is matched with the nutrient canal body and used for clamping and fixing the nutrient canal body; a groove is formed in the box body, a first pipe opening and a second pipe opening are formed in the box body, the nutrient canal body penetrates out of the second pipe opening after penetrating through the first pipe opening, the nutrient canal body located in the box body is clamped in the groove, and the nutrient canal body is pressed in the groove after the box cover is matched with the box body; a heating wire is arranged in the supporting table, and a regulator connected with the heating wire is arranged on the box body. The technical problems that in the prior art, when nutrient solution is heated in actual use, due to the fact that the heating part is short, the temperature is not easy to control, and the heating and heat preservation effects on the nutrient solution are poor are solved.

The invention provides a lacrimal passage indwelling administration wearable device and a use method. The problems that in the field of ophthalmology medical treatment, an existing lacrimal passage indwelling medical device is low in medicine utilization rate, a lacrimal passage is prone to bonding, and administration pressure controllability is poor are solved. The lacrimal passage indwelling administration wearable equipment comprises a circulating flow pipeline, the circulating flow pipeline comprises a three-way pipe, an indwelling pipeline and a backflow pipeline, the three-way pipe comprises a first communicating pipe, a second communicating pipe and a third communicating pipe, one ends of the first communicating pipe, one end of the second communicating pipe and one end of the third communicating pipe are communicated, and the two ends of the backflow pipeline are connected with the first communicating pipe and the second communicating pipe correspondingly; the indwelling pipeline comprises a medicine slow-release pipe and a circulating pipe of which one ends are communicated with each other, and the other end of the medicine slow-release pipe is connected with the third communicating pipe; the third communicating pipe is arranged in the lacrimal ductule of the patient, the medicine slow-release pipe is arranged in the lacrimal sac, and the other end of the circulating pipe penetrates out of the body from the nasal meatus of the patient and is connected into the backflow pipeline to form a medicine flowing loop; the invention discloses a head-mounted support and a drug delivery assembly arranged on the head-mounted support.