A calibrated DC compensation system for a wireless communication device configured in a zero intermediate frequency (ZIF) architecture. The device includes a ZIF transceiver and a baseband processor, which further includes a calibrator that periodically performs a calibration procedure. The baseband processor includes gain control logic, DC control logic, a gain converter and the calibrator. The gain converter converts gain between the gain control logic and the DC control logic. The calibrator programs the gain converter with values determined during the calibration procedure. The gain converter may be a lookup table that stores gain conversion values based on measured gain of a baseband gain amplifier of the ZIF transceiver. The gain control logic may further include a gain adjust limiter that limits change of a gain adjust signal during operation based on a maximum limit or on one or more gain change limits. A second lookup table stores a plurality of DC adjust values, which are added during operation to further reduce DC offset. The calibration procedure includes sampling an output signal for each gain step of the baseband amplifier at two predetermined range values and corresponding DC offsets using successive approximation. The data is used to calculate gain, DC offset and DC differential values, which are used to determine the conversion values programmed into the lookup tables or the gain adjust limiter.