375 results about "Stenosis" patented technology

An ablation catheter comprises a catheter body extending longitudinally between a proximal end and a distal end along a longitudinal axis; and an ablation element assembly comprising ablation elements connected to the catheter body, each ablation element to be energized to produce an ablation zone. The ablation elements are distributed in a staggered configuration such that the ablation zones of the ablation elements span one or more open arc segments around the longitudinal axis, but the ablation zones of all ablation elements projected longitudinally onto any lateral plane which is perpendicular to the longitudinal axis span a substantially closed loop around the longitudinal axis. Since the ablation zones do not form a closed loop, the risk of renal artery / vein stenosis is reduced or eliminated. Since the ablation zones of all ablation elements projected longitudinally onto any lateral plane span a substantially closed loop, substantially complete renal denervation is achieved.

A stent provided with a composition having at least one type of inhibitor of ATP synthesis, optionally together with at least one inhibitor of the pentose phosphate pathway is disclosed. The medical stent is useful for treating stenosis and preventing restenosis in vascular ducts and for treating cancerous tumors present in ducts, resectioned cavities and scars and any disorder arising from the proliferation of cells in ducts or cavities.

The present invention provides a stent delivery catheter that can place a stent in a tortuous narrowed area with good maneuverability while preventing falling or displacement of the stent. The present invention provides a stent delivery catheter for delivering a stent for treating stenosis in a body to a narrowed area. A distal end of the catheter includes a collapsible balloon in a collapsed state and the stent in an undeployed state, the stent being mounted on the outer surface of the collapsed balloon, the balloon having frustoconical tapered segments and a cylindrical straight tubular segment. An inner tube for defining a guidewire lumen extends into the interior of the balloon, and displacement prevention mechanisms for preventing the stent from moving in the longitudinal direction of the stent delivery catheter are affixed to the inner surface of the balloon only. Another aspect of the present invention provides a stent delivery catheter that can prevent the stent from moving in the axis direction of the catheter without requiring additional components or additional steps that complicate the manufacturing process. In this catheter, the thickness T1 of a near-center portion of the distal-end tapered segment and the thickness T2 of a near-center portion of the straight tubular segment satisfy a predetermined relationship, and the thickness T3 of a near-center portion of the proximal-end tapered segment and the thickness T2 of the near-center portion of the straight tubular segment satisfy a predetermined relationship. In this manner, the distal-end and proximal-end tapered segments in the collapsed state prevent the movement of the stent. The present invention also provides a preferable RX balloon catheter, i.e., a stent delivery catheter, having improved maneuverability and enhanced responsiveness for expansion and contraction of the balloon without complicating the manufacturing process or increasing the cost.

The invention discloses a method for automatically detecting a coronary artery calcified plaque of a human heart. The method comprises the following steps of S1.adopting a deep learning neural networkto segment an original graph of a coronary artery CTA sequence in order obtain a coronary artery extraction graph of the human heart; S2.processing the coronary artery extraction graph of the human heart to generate a straightening picture of each branch vessel; S3.carrying out blood vessel segmentation on each straightening picture to obtain a straightening blood vessel graph of each branch vessel; S4.adjusting a window width and a window level, calculating a pixel value of the whole picture of each straightening blood vessel graph, if a pixel point whose pixel value is greater than 220 exists, determining that a calcified plaque exists, and screening out the straightening blood vessel graph with the calcified plaque; S5.converting the straightening blood vessel graph with the calcifiedplaque into a grey scale graph, filling the pixel point whose gray value is larger than 220 with the color, and obtaining a calcified plaque extraction result; and S6.calculating a rate of stenosis ofthe blood vessel and obtaining a quantization value. The method is effective for detection of most calcified plaques, automatic detection can be realized, and the efficiency is greatly improved.

A catheter having a distal assembly with multiple spines with proximal ends affixed to the catheter and free distal ends. The spines have different lengths so distal ends of the spines trace different circumferences along an inner tissue surface of a tubular region to minimize risk of vein stenosis. The spine lengths can be configured so that the distal ends trace a helical pattern. The distal assembly may have a plunger which deflects the spines when moved longitudinally relative to the distal assembly. The catheter may include a second distal assembly distal of a first distal assembly wherein the first and second distal assemblies are separated by a fixed distanced or an adjustable distance.

The present invention relates to methods for inhibiting stenosis, obstruction, or calcification of a valve following implantation of a valve prosthesis which may involve disposing a coating composition on an elastical stent or valve leaflet. The valve prosthesis is mounted on the elastical stent such that the elastical stent is in contact with the valve.

A method and system for non-invasive assessment of renal artery stenosis is disclosed. A patient-specific anatomical model of at least a portion of the renal arteries and aorta is generated from medical image data of a patient. Patient-specific boundary conditions of a computational model of blood flow in the portion of the renal arteries and aorta are estimated based on the patient-specific anatomical model. Blood flow and pressure are simulated in the portion of the renal arteries and aorta using the computational model based on the patient-specific boundary conditions. At least one hemodynamic quantity characterizing functional severity of a renal stenosis region is calculated based on the simulated blood flow and pressure in the portion of the renal arteries and aorta.

A method and system for non-invasive hemodynamic assessment of coronary artery stenosis based on medical image data is disclosed. Patient-specific anatomical measurements of the coronary arteries are extracted from medical image data of a patient. Patient-specific boundary conditions of a computational model of coronary circulation representing the coronary arteries are calculated based on the patient-specific anatomical measurements of the coronary arteries. Blood flow and pressure in the coronary arteries are simulated using the computational model of coronary circulation and the patient-specific boundary conditions and coronary autoregulation is modeled during the simulation of blood flow and pressure in the coronary arteries. A wave-free period is identified in a simulated cardiac cycle, and an instantaneous wave-Free Ratio (iFR) value is calculated for a stenosis region based on simulated pressure values in the wave-free period.

This document provides devices and methods for the treatment of heart conditions, hypertension, and other medical disorders. For example, this document provides devices and methods for treating atrial fibrillation by performing thoracic vein ablation procedures, including pulmonary vein myocardium ablation. In some embodiments, the ablation is performed in coordination with the delivery a pharmacological agent that can abate the formation of tissue stenosis or neointimal hyperplasia caused by the ablation.

A sensor, sensor pad and sensor array for detecting infrasonic signals in a living organism is provided. The sensor, sensor pad and / or array can be utilized for detecting, determining and / or diagnosing level of stenosis, occlusion, or aneurysm in arteries, or other similar diagnosis. The sensor can include unique circuitry in the form of a piezoelectric plate or element sandwiched between two conductive O-rings.

Methods and devices for relieving stenoses in, or otherwise improving blood flow through, body lumens. Although applicable in a variety of different body lumens, the methods and devices of this invention are specifically useable for relieving stenoses in, or otherwise improving blood flow through, veins which drain blood from the brain for treatment of multiple sclerosis or other neurodegenerative disorders that are caused, triggered or exacerbated by venous occlusion or venous insufficiency.

The invention relates to an elastic tongue dorsum traction apparatus and a method for implanting the same. The elastic tongue dorsum traction apparatus and the method are used for treating patients suffering from sleep apnea-hypopnea syndromes or snoring. The elastic tongue dorsum traction apparatus comprises a tongue dorsum connecting mechanism, elastic traction bodies and tooth-side fixators. A support body of the tongue dorsum connecting mechanism is implanted under the mucosa of the tongue dorsum of a patient, and the elastic traction bodies and the tongue dorsum connecting mechanism are exposed out of the mucosa of the tongue dorsum of the patient. The tooth-side fixators are fixed to the inner sides of the teeth or the alveolar bones of the patient, one end of each elastic traction body is connected with the corresponding tooth-side fixator, and the other end of each elastic traction body is connected with the tongue dorsum connecting mechanism. The elastic tongue dorsum traction apparatus and the method have the advantages that the tooth-side fixators are used as support points, the elastic traction bodies can exert elastic tractive force on the tongue dorsum connecting mechanism, accordingly, the glossocoma tongue of the patient can be pulled up forwardly, airway stenosis and obstruction of the glossopharyngeal part of the patient can be prevented, and snoring and OSAHS (obstructive sleep apnea-hypopnea syndrome) treatment effects can be realized; an elastic traction effect is realized for the tongue dorsum connecting mechanism by the elastic traction bodies, so that movement of the tongue of the patient is unaffected while the tongue of the patient is moderately pulled up, certain swallowing and speaking functions can be kept, the airway of the glossopharyngeal part of the patient can be expanded, and the patient feels comfortable when using the elastic tongue dorsum traction apparatus.

A method and related system for providing therapy to a treatment site, such as stenosis or other vasculature disease, at one or more locations of a subject, such as the vasculature. The method includes: advancing an ultrasound catheter to or in proximity to the subject's treatment site; infusing microbubbles into or proximal to the treatment site; and delivering ultrasonic energy from the ultrasound catheter. The ultrasonic energy may be adapted for: imaging the treatment site, translating the microbubbles into or in the vicinity of the treatment site and / or rupturing the microbubbles.

Original 2D rotational projections are combined preferably in an overlaying manner with corresponding viewings of a 3D reconstruction. By showing the 2D rotational projections in combination with the 3D reconstruction, 3D vessel information can be compared with the original 2D rotational image information over different rotational angles. In a clinical setup the combined visualization will allow for an easy check if findings in the 3D RA volume such as stenosis or aneurysms are not overestimated or underestimated due to e.g. an incomplete filling with contrast agent and / or a spectral beam hardening during the rotational scan.

The invention relates to a degradable drug loading stent and a preparation method of the degradable drug loading stent. The degradable drug loading stent is characterized by comprising a skeleton structure made of a medical degradable metal or an alloy of the metal, a degradable macromolecular transition layer adhered to the surface of the skeleton structure and a drug loading layer. The degradable metal / macromolecular / drug multilayer composite stent provided by the invention has excellent mechanical property, degradable property and biocompatibility, and such drugs as taxol, taxol derivative, actinomycin D, 5-fluorouracil and sirolimus are loaded to the stent to perform active directional treatment on the focus position, so the stent is a functional degradable stent. The degradable multifunctional drug loading stent provided by the invention is suitable for interventional therapy in the blood vessel field and non-blood vessel fields and is especially suitable for interventional therapy of stenosis, obstruction or tumor of such non-blood vessel cavities as esophagus, bile duct, ductus pancreaticus, intestinal tract, urethral canal, trachea and bronchus, etc.

There is herein described an orthonostric device in the form of a nasal stent for insertion in the nostril of a patient for the correction of abnormalities and stenosis of the nostril. The stent is formed so that it can be expanded or contracted laterally by means of a tool which permits adjustment without the removal of the stent. A wire retaining clip is affixed to the stent and extends about the alar crease of the nose for retention of the stent. A method of forming the stent is also described which involves taking a casting of the patient's nostril, forming a mold and placing a resin liquid mix therein. Before setting of the resin, a separator or divider is inserted in the mold to separate the stent into two halves which are joined by a jack screw at the proximal end to permit adjustment by means of the tool.

It is described an improved visualization of an object under examination (107). Thereby, original 2D rotational projections are combined preferably in an overlaying manner with corresponding viewings of a 3D reconstruction. By showing the 2D rotational projections in combination with the 3D reconstruction, 3D vessel information can be compared with the original 2D rotational image information over different rotational angles. In a clinical setup the combined visualization will allow for an easy check if findings in the 3D RA volume such as stenosis or aneurysms are not overestimated or underestimated due to e.g. an incomplete filling with contrast agent and / or a spectral beam hardening during the rotational scan.

A method of processing images in images comprising curvilinear structures comprises, in parallel, a step of filtering said images and a decision step intended to select the pixels of the images pertaining to a curvilinear structure, the method comprising, in parallel, a sub-step of estimating the direction of each image pixel, as well as a sub-step of analyzing the connectivity of neighboring pixels based on their directions at the end of the sub-step of estimating the direction of each image pixel, and a sub-step of selecting groups of pixels as a function of the result of the sub-step of analyzing the connectivity of neighboring pixels based on their directions, at the end of the step of filtering. Such a method allows selection of curvilinear structures which are fine structures such as a catheter in a medical image, or thicker structures such as a tree-like structure of blood vessels. This method may be used, for example, in medical scanning apparatus for detecting artery anomalies such as stenosis or a diffuse coronary disease.

A method of assessing stenosis severity for a patient includes obtaining patient information relevant to assessing severity of a stenosis, including anatomical imaging data of the patient. Based on the anatomical imaging data, the existence of any lesions of concerns may be identified. A three dimensional image can be generated of any irregular shaped lesion of concern and a surrounding area from the patient anatomical imaging data. A plurality of comparative two dimensional lesion specific models may be created that have conditions that correspond to the three dimensional model. The comparative two dimensional models may represent vessels having regular shaped lesions with each of the comparative two dimensional models represents a different stenosis severity. The three dimensional model can then be mapped to one of the plurality of comparative two dimensional models. After this mapping, a diagnosis of whether the patient has coronary artery disease may be made.

The invention discloses an intravascular stent of a composite structure; the intravascular stent comprises a stent main body, wherein the distal end of the stent is restrained as an adducted form by virtue of a tightening wire, and the tightening wire is degradable magnesium alloy or degradable iron alloy; one or more auxiliary wires are woven on the stent main body; when the stent is applied to blood vessel of brain, the auxiliary wire is pure platinum or alloy thereof, pure gold or alloy thereof, pure tungsten or alloy thereof, or pure tantalum or alloy thereof; and when the stent is applied to peripheral blood vessel, the auxiliary wire is cobalt-chromium alloy or stainless steel or tungsten or tantalum. The stent, when serving as a thrombus removal system for treating cerebral apoplexy, not only can be used for removing thrombus effectively for several times but also can be used for catching small thrombus flowing to distal end so as to prevent distal blood vessels from getting blocked; and the stent can be used for dilating stenosis or blocked brain blood vessel or peripheral blood vessel, so as to take an effect of dredging and reconstructing a blood flow. The stent can be repositioned and released, with high controllability; and the stent can be used for reducing operation difficulty and greatly improving an operation success rate.

A system configured to assess the severity of a blockage in a vessel and, in particular, a stenosis in a blood vessel is disclosed. It is further disclosed to provide measurements of a vessel that allow assessment of the vessel and, in particular, any stenosis or lesion of the vessel and simulate diagnostic visualizations using a first visualization device and a second visualization device. Displaying, on a first visualization device, an image of the vessel with treatment diagnostic visualizations based on obtained pressure measurements and displaying, on a second visualization device, a portion of the image of the vessel with diagnostic visualizations based on the obtained pressure measurements is disclosed, wherein the portion of the image of the vessel displayed on the second visualization device is a close up of a region of interest of the vessel.

The invention relates to a fusion method for a coronary artery CT image and a cardiac ultrasonic strain image. The invention provides a multi-mode image fusion technology method for fusing and mappinga two-dimensional UCG image and a three-dimensional CT image to stereoscopically display coronary artery lesions and myocardial damage conditions. According to the method, The cardiac ultrasonic image and the CT image are fused for the first time; the ultrasonic cardiogram and the coronary artery CT image are fused (figure 1) through a one-point one-surface three-section positioning method; and athree-dimensional pattern diagram is displayed. Then, on the basis of a three-dimensional ultrasonic volume image, two-dimensional images (figure 2) of 20 sections and 480 grid segments of a left ventricular myocardium are obtained by adopting a central axis rotation method and a refined segmentation method; based on this, the strain values of 480 segments are obtained; and myocardial perfusion ischemia information obtained by three-dimensional strain is superimposed into the three-dimensional coronary artery vascular pattern diagram (figure 3), thereby accurately reflecting a relation between a myocardial ischemia area and an actual coronary artery stenosis.

A pneumostoma assessment and treatment system includes methods and devices for aftercare of a pneumostoma and for additional patient care utilizing a pneumostoma. The system utilizes a number of modalities to assess the health and functionality of the pneumostoma, the lungs and / or the patient as a whole. In response to an assessment of the health and functionality of the pneumostoma, lungs and patient, the tissues of pneumostoma may be treated with a treatment device and utilizing one or more different modalities to preserve or enhance the health and function of the pneumostoma and / or treat other conditions of the patient. Particular treatment modalities may be utilized to reduce tissue growth in and around the pneumostoma in order to prevent stenosis and maintain patency of the pneumostoma.

A system analyzes angiogram image data, including video data, in order to extract vasculature information. Advanced image processing and machine learning techniques are used in pre-processing, frame selection, and vasculature segmentation to remove classes of artifacts from angiogram videos, and specifically from frames selected as having a sufficient amount of image data. From segmentation, accurate vasculature diameters are calculated, and, in some examples, stenoses and / or the extent of stenosis is automatically determined and displayed.