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302 results about "Stenosis" patented technology

A stenosis (from Ancient Greek στενός, "narrow") is an abnormal narrowing in a blood vessel or other tubular organ or structure. It is also sometimes called a stricture (as in urethral stricture). Stricture as a term is usually used when narrowing is caused by contraction of smooth muscle (e.g. achalasia, prinzmetal angina); stenosis is usually used when narrowing is caused by lesion that reduces the space of lumen (e.g. atherosclerosis). The term coarctation is another synonym, but is commonly used only in the context of aortic coarctation.

Diagnostically useful results in real time

A method and apparatus for vascular assessment are disclosed. The apparatus, in some embodiments, receives, from a medical imaging device, a medical image of a coronary vessel tree of a subject and calculates a plurality of geometric measurements associated with individual portions of a vascular segment of the coronary vessel tree. The apparatus also determines a plurality of resistances associated with the plurality of geometric measurements associated with the individual portions of the vascular segment and determines a plurality of pressure drops across the individual portions of the vascular segment based on the determined resistances and a calculated or estimated blood flow. The apparatus further calculates based on the plurality of pressure drops, a functional index indicative of a presence or an absence of a stenosis within the vascular segment.
Owner:CATHWORKS LTD

Balloon catheter and methods of using the same

PendingUS20250352774A1Balloon catheterEustachian tube disordersAirway wall
Methods of treating a central airway obstruction (CAO), benign airway stenosis, asthma, chronic obstructive pulmonary disease (COPD), or an airway tumor in a human subject, methods of treating chronic rhinosinusitis (CRS) or chronic rhinosinusitis with nasal polyps (CRSwNP) in a human subject, methods of treating a eustachian tube disorder in a human subject, and devices and systems for performing the methods. A method of treating a central airway obstruction (CAO), benign airway stenosis, asthma, chronic obstructive pulmonary disease (COPD), or an airway tumor in a human subject includes inserting a drug-coated balloon catheter into a target site in a trachea, mainstem bronchus, bronchus intermedius, lobar bronchus, segmental bronchus, or sub-segmental bronchus, wherein the balloon is coated with a coating layer including the therapeutic agent and one or more additives. The therapeutic agent includes paclitaxel, sirolimus, or a derivative thereof. The method includes inflating the balloon to dilate the airway and deliver a therapeutic agent to the airway wall. The method includes deflating the balloon. The method also includes withdrawing the balloon catheter from the target site.
Owner:AIRIVER MEDICAL INC

Systems, devices, and methods for spine analysis

Embodiments include example systems, methods, and computer-accessible mediums for analysis of anatomical images for assessment of stenosis and disc degeneration. In some embodiments, systems, devices, and methods described herein include selecting a region of interest (ROI) in a three-dimensional (3D) volume of image data of a plurality of vertebra of a spine, identifying one or more anatomical parts in the ROI, determining one or more parameters of the one or more anatomical parts, and assessing a severity of a spinal deformity based on the one or more parameters.
Owner:AUGMEDICS INC

Comuter-implemented method and system for calculating a pressure drop along vessels

A computer-implemented method and a system for calculating a pressure drop along one or more vessels comprising one or more stenosis, the method comprising: obtaining at least one two-dimensional image of the vessels; obtaining a centerline and a boundary of each vessel by image processing algorithms; calculating a length and a diameter of each vessel; calculating a baseline volumetric flow (Qb); deriving a hyperaemic volumetric flow rate (Qh); determining a set of stenosed parts; defining a proximal part, between an inlet and a first stenosed part, a distal part, between last stenosed part and outlet, and a set of normal parts, between two stenosed parts; calculating a pressure drop at a proximal part, at a distal part, at normal parts and at stenosed parts, and calculating a total pressure drop ΔP from inlet to outlet of the vessel. Also, calculating resistance indices of the stenosis and of the microcirculation.
Owner:MEDLYTIC LABS

Automated measurement system and method for coronary artery disease scoring

ActiveUS12343119B2Image enhancementMedical imagingCoronary arteriesCoronary artery disease
An automated measurement device and method for coronary artery disease scoring is disclosed. An example device includes a processor configured to obtain a computerized model of a plurality of vascular segments of a patient and create an unstenosed computerized model from the computerized model by virtually enlarging at least some locations of the vascular segments of the computerized model. The processor also determines vascular state scoring tool (“VSST”) scores based on characteristics of vascular locations along the vascular segments. The processor further determines a severity of stenosis for the vascular locations based on comparisons of first blood flow parameter values at the vascular locations in the computerized model to corresponding second blood flow parameter values at the same vascular locations in the unstenosed computerized model. A user interface of the device displays the severity of stenosis in conjunction with the VSST scores for the vascular locations.
Owner:CATHWORKS LTD

Interventional operation system with OCT (optical coherence tomography) probe

The utility model discloses an interventional operation operating system with an OCT probe, and relates to the technical field of medical instruments. The interventional surgery operating system with the OCT probe comprises a micro catheter, a probe head and an OCT probe, the OCT probe is arranged at the front end of the micro catheter; the recovery pipe is arranged at the front end of the OCT probe; the recovery pipe is provided with a first through hole and a second through hole; a first control microfilament and a protective umbrella; the front end of the first control microfilament is connected with the protective umbrella; the front end of the first control microwire can penetrate into the recycling pipe through the first through hole; a micro guide wire; the front end of the micro guide wire can penetrate into the recycling pipe through the second through hole. According to the application, the micro catheter does not need to be drawn out of the carotid artery, then the OCT probe is inserted into the carotid artery, and scanning detection of a narrow part can be realized only by moving the micro catheter in the carotid artery by a small distance (dozens of millimeters or dozens of millimeters).
Owner:BEIJING TIANTAN HOSPITAL AFFILIATED TO CAPITAL MEDICAL UNIV

Laser intravasular lithotripsy device for stenosis calcified lesions

Laser IVL systems and methods are disclosed. A laser IVL system can include at least one light energy source and a catheter. The catheter can include an elongate sheath, an enclosure sealed to a distal end of the elongate sheath, and at least one optical fiber contained within the elongate sheath. The enclosure may have a fill volume less than 10 mL and may be fillable with a fluid. The at least one optical fiber can be optically coupled to receive light from the at least one light energy source and configured to transmit the received light at a light emitting region of the at least one optical fiber into a distal region of the catheter that is enclosed by the enclosure to generate shock waves in the fluid.
Owner:SHOCKWAVE MEDICAL INC

Spatial registration and image fusion method for deep learning based on SS-OCT and TOF data

The invention discloses a spatial registration and image fusion method for deep learning based on SS-OCT and TOF data, relates to the technical field of multi-modal medical image processing, and aims to improve alignment and fusion effects based on SS-OCT and TOF blood vessel data. According to the method, firstly, blood vessel features are enhanced through preprocessing, precise registration and fusion of cross-modal data are achieved by combining high-resolution two-dimensional tomography of SS-OCT and three-dimensional blood vessel form data of TOF and utilizing an improved SIFT algorithm and a cross attention Transformer model, and finally a high-precision three-dimensional blood vessel model is generated and can be used for treating cerebrovascular diseases (such as cerebrovascular diseases). Image support with details and a global structure is provided for preoperative planning and intraoperative navigation of a patient (such as aneurysm and stenosis), and the accuracy of diagnosis and treatment is remarkably improved.
Owner:CHANGCHUN UNIV OF SCI & TECH

Pressure sensing ureter guiding sheath

The invention relates to the technical field of medical apparatus and instruments, in particular to a pressure sensing ureter guiding sheath which comprises a flexible sheath tube body provided with a near-end operation section and a far-end intervention section. The annular pressure sensing array is formed by equidistantly arranging a plurality of piezoresistive sensors along the circumferential direction of the far-end intervention section, and is used for monitoring the ureter wall contact pressure in real time; the signal processing module is integrated on the near-end operation section and is used for carrying out dynamic noise filtering and baseline calibration on the pressure signals from the annular pressure sensing array; and the display screen is connected to the signal processing module and is used for displaying the pressure distribution of the annular pressure sensing array in real time. The scheme is used for solving the problem of mechanical trauma caused by inappropriate size selection, pathological or physiological stenosis and the like in the sheathing canal implantation process in the prior art, and real-time monitoring and dynamic adjustment of the ureter wall contact pressure are realized, so that the surgical risk is reduced, and the surgical success rate is improved.
Owner:BEIJING TSINGHUA CHANGGUNG HOSPITAL

Mastoid perfusion balloon and balloon dilatation catheter

The invention discloses a perfusion mastoid balloon and a balloon dilatation catheter, and relates to the technical field of medical instruments. The perfusion mastoid balloon comprises a balloon main body, mastoids and a fluid channel, the mastoid process and the balloon main body are integrally formed or separately formed; the fluid channel is formed in the peripheral wall of the balloon body and extends in the length direction of the balloon body to allow liquid to pass through, and the size of the fluid channel in the radial direction of the balloon body is smaller than or equal to the size of the mastoid in the radial direction of the balloon body. The structure of the perfusion mastoid balloon is improved, the expansion time of the perfusion mastoid balloon is effectively prolonged, a narrow area can be better expanded, and meanwhile blood vessel blockage is avoided.
Owner:DK MEDICAL TECH CO LTD

Application of monascus composition in preparation of medicine for treating coronary microcirculation disturbance

ActiveCN120771236ACardiovascular disorderPlant ingredientsPerivascular edemaMonascus anka
The invention provides application of a monascus composition in preparation of a medicine for preventing and / or treating coronary microcirculation disturbance. The monascus composition comprises one or more of cortex mori, ramulus mori and folium mori, monascus and radix puerariae. When the composition containing the red yeast rice is applied to preparation of the medicine for preventing and / or controlling coronary microcirculation disturbance, the abnormal microvascular structure can be improved (myocardial microvascular density MVD is increased, edema around microvessels is relieved, the lumen stenosis phenomenon is improved, and the endothelial cell condition is good); 2) microvascular occlusion is improved (pathologic results show that microvascular contents are reduced); (3) the abnormal vasodilatation and contraction function of the microvessels is improved (NO is increased); 4) improving blood lipid metabolism disorder; and (5) the heart function is improved (the left ventricular ejection fraction LVEF and the left ventricular short axis shortening rate LVFS are improved, and the left ventricular pressure maximum rising rate LV + dp / dtmax and the left ventricular pressure maximum falling rate LV-dp / dtmax are increased).
Owner:BEIJING WBL PEKING UNIV BIOTECH

Ureter safe expansion guide wire system and progressive pressure control method

The invention discloses a safe ureter dilatation guide wire system and a progressive pressure control method, and relates to the technical field of medical instruments.The safe ureter dilatation guide wire system comprises a guide wire body and a pressure sensor, the guide wire body comprises a water bag structure and a double-cavity structure which are communicated, the water bag structure is made of an elastic structure, and the double-cavity structure is made of an elastic material; the interior of the water bag structure is used for being filled with expansion liquid and expanding according to the target volume so as to expand the narrow position of the ureter. A guide wire cavity and a liquid injection cavity which are independently arranged are formed in the double-cavity structure, the guide wire cavity and the liquid injection cavity are both communicated with the water bag structure, the guide wire cavity is used for allowing the identification light source to penetrate through, and the liquid injection cavity is used for providing expansion liquid for the water bag structure; the pressure sensor is installed outside the water bag structure so as to detect the pressure of the inner wall tissue of the ureter in real time. According to the technical scheme, the problem that an existing ureter guide wire cannot monitor the deformation state of narrow tissue in real time is solved.
Owner:SHENZHEN LONGHUA DISTRICT PEOPLES HOSPITAL

Potential stroke risk assessment method and system after coronary artery recanalization operation

PendingCN120600291AMedical simulationHealth-index calculationBlood flowCerebrovascular imaging
The invention discloses a potential stroke risk assessment method and system after coronary artery recanalization, and the method comprises the steps: obtaining the heart and cerebral vessel image data of a patient, and constructing a complete heart and cerebral artery blood vessel geometric model; based on the cardio-cerebral artery blood vessel geometric model, numerical simulation is conducted on the flowing conditions of blood flow in coronary arteries and cerebral vessels by means of a computational fluid mechanics method, and the pressure ratio before and after coronary artery stenosis and the partial pressure ratio of the cerebral vessels are calculated; according to the pressure ratio and the partial pressure ratio, the potential risk of the cerebral arterial thrombosis is quantitatively evaluated, and a cerebral blood flow partial pressure ratio numerical value and a cerebral arterial thrombosis risk evaluation report are generated. According to the cerebral apoplexy risk quantitative evaluation method, by integrating coronary artery CTA and cranial CTA or MRA data, reconstructing a complete heart and cerebral vessel geometric model and simulating heart and cerebral blood flow changes before and after a coronary artery recanalization operation, and particularly by calculating coronary artery FFR and cerebral blood flow partial pressure ratio FPR, an evaluation report is generated, and a basis for quantitative evaluation of the cerebral apoplexy risk in the operation is provided for clinical doctors.
Owner:SHENZHEN INST OF ADVANCED TECH CHINESE ACAD OF SCI +1

Intervertebral joint osteoarthritis image feature evaluation method based on deep learning

ActiveCN121121201AImage analysisDrawing from basic elementsOssicular erosionData set
The invention relates to the technical field of medical image auxiliary diagnosis, and provides an intervertebral joint osteoarthritis image feature evaluation method based on deep learning, which can synchronously identify five types of FJOA image features such as joint space stenosis, osteophyte, hypertrophy, subchondral bone erosion and subchondral cyst, and improves the comprehensiveness and efficiency of evaluation. The nnU-Net model is adopted to perform high-precision segmentation on an intervertebral joint region, so that the positioning precision is effectively improved; by introducing a shared feature extraction network based on ResNet-18 and five parallel classification sub-networks, joint modeling of multi-scale semantic information is realized, and the recognition accuracy and generalization ability of the model are improved; according to the method, a Grad-CAM technology is combined to generate an activation thermodynamic diagram, a model interpretation basis is superposed to an original image, visual display of an evaluation result is realized, interpretability and clinical applicability of the model are enhanced, and FJOA image features in axial lumbar vertebra CT images from two central data sets can be quantitatively evaluated so as to comprehensively quantify individual FJOA image features.
Owner:FIRST PEOPLES HOSPITAL OF YUNNAN PROVINCE

Branch vessel endoluminal repair system

The invention relates to a branch blood vessel endoluminal repair system which comprises at least two guide wires and a support conveying device, the support conveying device comprises an outer sheath tube and a film covering tube which are connected in a sleeved mode, and the film covering tube comprises a main body part connected to the at least two guide wires in a sleeved mode. The main body part and the at least two branch parts are connected to the guide wires in a sleeving mode in a one-to-one correspondence mode, the film covering pipe is provided with a containing position and a working position, the film covering pipe is folded to the inner side of the outer sheath pipe at the containing position, and the main body part and the branch parts move to the outer portion of the outer sheath pipe at the working position, so that the main body part and the branch parts form a cavity channel used for implanting a support. By means of the technical scheme, the branch blood vessel intracavitary repair system can solve the problems including but not limited to iliac artery lesions (such as dilatation and stenosis lesions), the application requirement suitable for a complex blood vessel structure is met, and the applicability is high.
Owner:李雷

Robot guiding path optimization method and system for gastrointestinal tumor assisted surgery

The invention discloses a robot guide path optimization method and system for gastrointestinal tumor assisted surgery, particularly relates to the technical field of robot assisted navigation, and is used for solving the problem of unstable and inaccurate path planning. According to the method, fusion of multi-modal information under the unified time and space is achieved through space-time alignment of a preoperative model and intraoperative perception data, registration uncertainty and visibility indexes are dynamically calculated, and the fusion of the multi-modal information under the unified time and space is achieved through construction of an anatomical risk layer, a forbidden zone, geometric stenosis, perfusion evidence, a collision distance margin and a puncture point remote rotation center constraint satisfaction degree. A multi-channel path cost graph is generated, the safety of the path is evaluated, a constraint propagation and regulation causal graph mechanism is combined, a conflict solution contribution degree and a path optimization priority sequence can be rapidly output, it is ensured that the robot executes the optimal path in a complex anatomical environment, a conservative mode is switched when a key risk index triggers a threshold value, and the optimal path is obtained. Real-time regulation and control and safety guarantee are achieved, and the stability of the operation process is improved.
Owner:南昌大学第一附属医院

Venous stent with high flexibility

PendingCN120093482AStentsBlood vesselsVenous stentStent implantation
The invention relates to a vein stent with high flexibility, a far-end woven stent is formed by weaving metal wires with coatings and has high flexibility, and the expansion diameter of the stent is slightly larger than the diameter of a target vein but smaller than that of a near-end laser engraving stent; the far-end woven stent comprises a metal wire and a coating located outside the metal wire, the coating is divided into an inner side coating and an outer side coating, the radian proportion of the inner side coating is larger than that of the outer side coating, and the surface roughness of the inner side coating is smaller than that of the outer side coating; and the group of metal connecting short rods are connected with the near-end laser engraving bracket and the woven bracket through welding. The stent has different structure and mechanical characteristics in vein segments with different anatomy and kinematic mechanics characteristics, is better in targeted adaptability, and can better meet the requirements of stent fixation and cross-joint stent placement in iliofemoral vein stent implantation of patients with non-thrombotic iliofemoral vein stenosis occlusion diseases.
Owner:SHANGHAI NINTH PEOPLES HOSPITAL SHANGHAI JIAO TONG UNIV SCHOOL OF MEDICINE

Stent expanding balloon with friction enhancing materials and features

Medical balloons and methods used to retain and expand a stent within a stenosis or stricture of a bodily passage are disclosed. The balloons include a base material layer and a friction enhancing feature coupled to an exterior surface of the base material layer. The friction enhancing feature includes a second material layer disposed over the exterior surface to form a laminar formed balloon. The second material layer is more compressible than the base material layer to provide an increased static stent holding force.
Owner:MERIT MEDICAL SYSTEMS INC

Bending-adjustable endovascular shock wave catheter assembly

The invention discloses a bending-adjustable intravascular shock wave catheter assembly, which relates to the technical field of medical instruments and comprises a catheter, an electrode fixing seat, a balloon, a forward shock wave generating electrode pair, a handle, a balloon control assembly, a shock wave control assembly and a four-way bending adjusting assembly, the electrode fixing seat and the balloon are arranged at one end of the catheter; the forward shock wave generating electrode pair is arranged on the electrode fixing seat and is positioned in the balloon; the handle is connected with the catheter; the balloon control assembly is connected with the balloon; the shock wave control assembly is connected with the forward shock wave generation electrode pair; the four-direction bending adjusting assembly is arranged in the guide pipe. The unique design structure can be compatible with a plaque opening electrode pair, and an occluded plaque can be opened forwards, so that the catheter can smoothly pass through a lesion position with relatively high stenosis; and the catheter can smoothly pass through tortuous blood vessels with various difficulties without the help of a guide wire, so that the catheter can smoothly reach a lesion position to carry out treatment.
Owner:XIANGYA HOSPITAL CENT SOUTH UNIV +1

Lindera glauca extract, preparation method thereof and application of lindera glauca extract in preparation of medicine for preventing and / or treating rheumatoid arthritis

The invention discloses a lindera glauca extract, a preparation method thereof and application of the lindera glauca extract in preparation of drugs for preventing and / or treating rheumatoid arthritis. The research finds that the lindera glauca extract can obviously reverse arthritic rat plantar part swelling and toe bending, relieve ankle joint injury, relieve synovial hyperplasia and inflammatory cell infiltration, inhibit joint fusion, relieve joint gap stenosis, relieve articular surface fusion tendency, increase bone mineral density and bone trabecula number, reduce bone trabecula separation degree and improve joint fusion. The lindera glauca extract can be used for relieving rheumatoid arthritis by protecting the inherent structure of joint tissues and improving inflammation, so that a novel natural medicine choice is provided for preventing and / or treating rheumatoid arthritis.
Owner:WUHAN CHINESE & WESTERN MEDICINE UNION HOSPITAL

Carotid artery image-oriented image processing and simulation analysis method

The invention discloses an image processing and simulation analysis method for a carotid artery image, which comprises the following steps: firstly, acquiring a CTA image, observing and selecting, then importing the CTA image, adjusting the image contrast, generating a three-dimensional blood vessel model, extracting a carotid artery focus, and carrying out overall and local surface optimization processing on the model. The method comprises the steps that firstly, a model is built, then local surface cutting naming and grid division are conducted on the model, finally parameters are set, CFD hemodynamic simulation is conducted, a simulation result is subjected to visualization processing, and preoperative and postoperative data are compared and analyzed. According to the method, multi-modal imaging data of brain CT perfusion imaging, brain CT angiography and the like of a patient suffering from carotid artery stenosis can be collected to be used for reconstructing a three-dimensional model of the carotid artery stenosis, the carotid artery hemodynamic characteristics of the patient and the individual characteristics of the patient are analyzed in an auxiliary mode based on computational fluid mechanics, operation mode selection is optimized, and the three-dimensional model of the carotid artery stenosis is reconstructed. Cerebral ischemia reperfusion injury is avoided, clinical prognosis of a patient is improved, and life quality of the patient is improved.
Owner:UNIV OF ELECTRONICS SCI & TECH OF CHINA

A Data Processing System and Computer Implemented Method for Quantifying a Stenosis in a Vessel

A data processing system and computer implemented method for quantifying a stenosis in a vessel.There is described a data processing system (30), which receives a dataset (32) comprising a set of pressure values measured during a pullback time period (40), the pullback time period (40) corresponding to the time period during which the set of pressure values were determined from measurements of a movable pressure sensor (22) while moving along a part (12) of a vessel (10). Based on a time window (42) of which the duration corresponds to a fraction of the pullback time period, there is calculated a maximum of the moving time window (42) pressure change (26) based on said dataset (32) of said part (12) of said vessel (10).
Owner:ARTERIAX BV

Dynamic evaluation method and device for NVC function of carotid artery stenosis crowd, medium and program product

The embodiment of the invention provides a dynamic evaluation method and device for the NVC function of a carotid artery stenosis crowd, a medium and a program product, and relates to the field of intelligent medical treatment. The method comprises the following steps: acquiring a resting middle cerebral artery average blood flow velocity Vm of a sample in a resting state and an exercise middle cerebral artery average blood flow velocity Vm of the sample in an exercise load state; according to the average blood flow velocity Vm of the middle cerebral artery during movement and the average blood flow velocity Vm of the middle cerebral artery during resting, a movement-induced blood flow response index EIFR is obtained through calculation; the motion-induced blood flow response index EIFR is an NVC parameter; and obtaining an evaluation result of whether the NVC function is abnormal or not according to whether the NVC parameter is reduced or not. On the basis of a quantifiable NVC function evaluation system in a constant motion state, objective screening standards are provided for stroke high-risk groups, a long-term follow-up visit plan is made, and an accurate quantitative basis is provided for clinical intervention decision and postoperative complication prediction.
Owner:XUANWU HOSPITAL OF CAPITAL UNIV OF MEDICAL SCI

Internal arteriovenous fistula monitoring method and system

The invention provides an internal arteriovenous fistula monitoring method and system, and the method comprises the steps: extracting feature parameters based on the blood vessel pulsation sound of an internal arteriovenous fistula region, preprocessing the feature parameters, and inputting the preprocessed feature parameters into a first prediction model, thereby obtaining a stenosis probability; extracting risk factors from a biochemical examination result, preprocessing the risk factors, and inputting the preprocessed risk factors into a second prediction model to obtain a sequence of contribution degrees of the risk factors to the internal fistula stenosis from high to low; the stenosis probability and the contribution degree of the first L risk factors are input into a risk assessment model, the internal arteriovenous fistula risk level is obtained, and the risk assessment model is integrated based on a TOPSIS multi-index weighting method weighted by equal weights. The invention provides an internal arteriovenous fistula monitoring method and system which are used for solving the problems that a palpation method is greatly influenced by experience and subjective judgment of medical staff, and an ultrasonic monitoring method is expensive in equipment, large in size, complex in operation, not suitable for daily monitoring and incapable of providing a remote monitoring function.
Owner:THE CENTRAL HOSPITAL OF WUHAN (WUHAN NO 2 HOSPITAL WUHAN CANCER RESEARCH INSTITUTE)

Multifunctional anti-stenosis drug coating stent as well as preparation method and application thereof

ActiveCN120459385ASurgeryCoatingsBile duct stricturesPharmaceutical drug
The invention discloses a multifunctional anti-stenosis drug-coated stent which comprises a nickel-titanium stent, the outer surface of the nickel-titanium stent is coated with a PLLA-TPU-based drug-loaded coating, and a drug-loaded film is attached to the inner surface of the nickel-titanium stent. The body of the prepared multifunctional anti-stenosis drug-coated stent is a nickel-titanium stent and has good biocompatibility, the outer surface of the stent is coated with PLLA-TPU-based drug-loaded coating suspension slurry, the stent has good degradation performance and adjustable mechanical performance, inward or outward overgrowth of tumor cells can be effectively inhibited through drug release, and the anti-stenosis drug-coated stent has good anti-stenosis effect on tumor cells. Meanwhile, the medicine carrying membrane on the inner layer of the nickel-titanium stent can effectively inhibit tumor cells and effectively prevent bile mud from being deposited, and the nickel-titanium stent can be used for treating biliary tract stenosis diseases. The invention further provides a preparation method of the multifunctional anti-stenosis drug coating stent, the stent is prepared through a liquid flame spraying technology and a lamination method, the preparation method is simple, and the preparation period is short.
Owner:NINGBO INST OF MATERIALS TECH & ENG CHINESE ACAD OF SCI +3

A small-caliber bipolar plasma resectoscope

ActiveCN115300092BSurgical instruments for heatingCervical surgeryRESECTOSCOPE
The present invention relates to a small-caliber bipolar plasma resectoscope, comprising an outer sheath, an inner sheath, and an electrode loop assembly. The electrode loop assembly is installed in the inner sheath and can move along the extension direction of the inner sheath. The electrode loop assembly comprises a linearly distributed positive electrode, an insulator, and a negative electrode, which are fixedly connected in sequence. The positive electrode comprises an extension section, a first bending section, and a second bending section. The extension direction of the first bending section forms a first angle with the horizontal plane. The extension direction of the second bending section forms a second angle with the horizontal plane. When energized, the positive electrode and the negative electrode form an electrical circuit with the physiological saline perfused in the electrode loop. While meeting normal electroresection conditions, the resectoscope increases the cutting and hemostasis efficiency of a simple linear electrode loop, achieves the goal of reducing the circumference of the resectoscope outer sheath to a minimum of Fr16, meets the needs of transurethral / cervical surgery for patients with a small urethral circumference or urethral / cervical stenosis, and reduces the problems of urethral / cervical injury and postoperative urethral / cervical stenosis caused by the excessive circumference of a conventional Fr26 resectoscope.
Owner:安徽易镜医疗科技有限公司

Computer-implemented method and system for calculating a pressure drop along vessels

PCT designated stage expiredWO2025093652A1CatheterAngiographyImaging processingMedicine
A computer-implemented method and a system for calculating a pressure drop along one or more vessels comprising one or more stenosis, the method comprising: obtaining at least one two-dimensional image of the vessels; obtaining a centerline and a boundary of each vessel by image processing algorithms; calculating a length and a diameter of each vessel; calculating a baseline volumetric flow (Q b ); deriving a hyperaemic volumetric flow rate (Q ℎ); determining a set of stenosed parts; defining a proximal part, between an inlet and a first stenosed part, a distal part, between last stenosed part and outlet, and a set of normal parts, between two stenosed parts; calculating a pressure drop at a proximal part, at a distal part, at normal parts and at stenosed parts, and calculating a total pressure drop ΔP from inlet to outlet of the vessel. Also, calculating resistance indices of the stenosis and of the microcirculation.
Owner:MEDLYTIC LABS

Postoperative Risk Assessment System, Device, Storage Medium, and Program Product

ActiveCN119446541BHealth-index calculationRegression analysisIliac artery bypass
The present invention provides a postoperative risk assessment system, device, storage medium and program product, relating to the field of computer technology. The system includes: an extraction module for extracting independent risk factors for early saphenous vein graft failure from the postoperative data of a patient; a score determination module for determining the scores of each factor in the independent risk factors based on the scoring scale in the nomogram model, where the nomogram model is constructed based on the independent risk factors; and a prediction module for predicting the risk information of early saphenous vein graft failure after coronary artery bypass grafting based on the risk coefficient corresponding to the total score of each factor in the independent risk factors. Based on the results of Lasso regression analysis and Logistic regression analysis, the present invention constructs a prediction model for early saphenous vein graft failure with risk factors such as QFR > 0.80, PI > 3.0, complications, and non-left main stenosis as the main body, thereby improving the accuracy of the risk assessment of early saphenous vein graft failure in postoperative patients.
Owner:FUWAI HOSPITAL CHINESE ACAD OF MEDICAL SCI & PEKING UNION MEDICAL COLLEGE

Method and apparatus for evaluating stenosis in spinal canal and nerve root canal

PCT designated stage expiredWO2025127334A1Medical simulationImage analysisSpinal columnSpinal stenosis
The present invention pertains to a stenosis evaluation method implemented by a processor, comprising the steps of: acquiring a medical image by photographing the spine of an individual; dividing a region for evaluating spinal stenosis in the medical image by using a division model trained to divide the region for evaluating spinal stenosis by using the medical image as an input; and calculating, on the basis of the divided region, the size of a section in which spinal stenosis of the individual can be evaluated.
Owner:GACHON UNIV OF IND ACADEMIC COOPERATION FOUND

Dynamic DR digestive tract radiography automatic tracking and focus marking system

The invention relates to the technical field of medical image analysis, in particular to a dynamic DR digestive tract radiography automatic tracking and focus marking system which comprises a dynamic DR imaging module, an image real-time processing module, a contrast agent motion tracking module and a focus intelligent marking module. A deep learning algorithm is utilized to segment a contrast agent flowing area in real time and construct a dynamic three-dimensional model of a digestive tract, a contrast agent movement track is analyzed and tracked in combination with time-space domain features, and meanwhile, based on morphological anomaly detection and comparison with a focus feature library, focus positions such as stenosis, ulcers and space-occupying lesions are automatically marked; the problems of image blurring and tracking offset caused by alimentary canal peristalsis are solved by adopting a self-adaptive registration optimization algorithm of dynamic DR images and motion characteristics of alimentary canal contrast agents; by means of the method, the problems that traditional digestive tract radiography depends on manual interpretation of dynamic DR images, the focus tracking efficiency is low, and marking is prone to omission are solved.
Owner:THE FIRST AFFILIATED HOSPITAL OF GUANGZHOU MEDICAL UNIV (GUANGZHOU RESPIRATORY CENT)