13 results about "Autoregulation" patented technology

A portable device for quantitative measurement of tissue autoregulation and neurovascular coupling via portable measurement of blood flow, oxygenation, metabolism, and / or EEG signals and methods for using said device. The device may comprise a body and a plurality of legs pivotably attached to the body. The plurality of legs may comprise at least one reference electrode leg and at least one measurement electrode leg for electrical measurement, and an optical detection fiber leg and at least one optical source fiber leg for optical blood flow, oxygenation, and metabolism measurement. The present invention is additionally directed to a portable device for blood flow measurement and therapeutic photobiomodulation. The device may comprise a body and a plurality of legs. The plurality of legs may comprise at least one optical detection fiber leg and at least one optical source fiber leg, and at least one leg for therapeutic photobiomodulation.

In some examples, a method includes receiving a signal indicative of a blood pressure of a patient and identifying at least one first portion of the signal comprising a first characteristic of the signal exceeding a first threshold. The method also includes identifying at least one first portion of the signal comprising a second characteristic of the signal exceeding a second threshold, the first characteristic being different than the second characteristic. The method further includes determining a filtered signal indicative of the blood pressure of the patient by excluding the at least one first portion and the at least one second portion from the signal. The method includes determining a set of mean arterial pressure values based on the filtered signal and determining an autoregulation status of the patient based on the set of mean arterial pressure values.

A muscle and bone dredging instrument disclosed by the present invention comprises a host and a pole piece, the host is provided with a display screen and a host power line, the host is provided with an adjusting key, a display lamp, a plurality of keys and a wire plugging hole, the pole piece is provided with an electrode socket, one end of the electrode socket is provided with a pole needle, and the other end of the electrode socket is provided with a wire. The invention relates to the technical field of physiotherapy equipment, and the core principle is that positioning electric energy is output through a body-controlled high-energy biological electro-therapeutic apparatus and is conducted to the body of a patient by a professionally trained electro-therapist through self-adjustment of current intensity, and sine wave current matched with human body cell bioelectricity waveform is utilized to excite essence and qi to dredge the channels and collaterals, so that the body-controlled high-energy biological electro-therapeutic apparatus can be used for treating body diseases. Therefore, the treatment effect that pain is not caused by general communication is achieved.

A method for monitoring autoregulation includes, using a processor, using a processor to execute one or more routines on a memory. The one or more routines include receiving one or more physiological signals from a patient, determining a correlation-based measure indicative of the patient's autoregulation based on the one or more physiological signals, and generating an autoregulation profile of the patient based on autoregulation index values of the correlation-based measure. The autoregulation profile includes the autoregulation index values sorted into bins corresponding to different blood pressure ranges. The one or more routines also include designating a blood pressure range encompassing one or more of the bins as a blood pressure safe zone indicative of intact regulation and providing a signal to a display to display the autoregulation profile and a first indicator of the blood pressure safe zone.

An example autoregulation monitoring system includes processing circuitry configured to receive a blood pressure signal indicative of a blood pressure of a patient; determine a derivative of at least a portion of the blood pressure signal; determine, based on the derivative, a characteristic arterial pressure (CAP) value; determine, based on the CAP value, an autoregulation value of the patient; and output a signal indicative of the autoregulation value of the patient.

A method for monitoring autoregulation includes, using a processor, using a processor to execute one or more routines on a memory. The one or more routines include receiving one or more physiological signals from a patient, determining a correlation-based measure indicative of the patient's autoregulation based on the one or more physiological signals, and generating an autoregulation profile of the patient based on autoregulation index values of the correlation-based measure. The autoregulation profile includes the autoregulation index values sorted into bins corresponding to different blood pressure ranges. The one or more routines also include designating a blood pressure range encompassing one or more of the bins as a blood pressure safe zone indicative of intact regulation and providing a signal to a display to display the autoregulation profile and a first indicator of the blood pressure safe zone.

A system includes a first sensor to continuously measure a signal of a renal blood flow of a patient. A second sensor continuously measures an arterial pressure signal of the patient. A blood flow monitor is in communication with the first and second sensors. The blood flow monitor includes system memory that stores monitoring software code and a processor. The processor is configured to execute the monitoring software code to estimate a flow rate of the renal blood flow of the patient from the signal of the renal blood flow and monitor changes in the flow rate of the renal blood flow over time. The processor is also configured to execute the monitoring software code to monitor changes in the arterial pressure signal over time and evaluate a mathematical relationship between the changes in the arterial pressure signal and the changes in the flow rate of the renal blood flow.

The present invention relates to a therapeutic agent comprising an automodulating element, preferably wherein the therapeutic agent is an antigen binding protein. Also disclosed are several methods of treatment comprising the use of the medicament.

The system includes a first sensor for continuously measuring a signal of renal blood flow of a patient. The second sensor continuously measures an arterial pressure signal of the patient. A blood flow monitor is in communication with the first and second sensors. The blood flow monitor includes a processor and a system memory storing monitoring software code. The processor is configured to execute the monitoring software code to assess a flow rate of the renal blood flow of the patient from the renal blood flow signal and to monitor a change in the flow rate of the renal blood flow over time. The processor is further configured to execute the monitoring software code to monitor changes in the arterial pressure signal over time and evaluate a mathematical relationship between the changes in the arterial pressure signal and changes in the flow rate of the renal blood flow.

A monitor configured to monitor autoregulation includes a memory encoding one or more processor-executable routines and a processor configured to access and execute the one or more routines encoded by the memory. When executed, the routines cause the processor to receive one or more physiological signals from a patient, determine a measure indicative of an autoregulation status of the patient based on the one or more physiological signals, generate an autoregulation alarm indicative of an impaired autoregulation status when the measure exceeds a predetermined threshold for more than a predetermined period of time.

The present invention relates to a therapeutic agent comprising an autoregulation element, preferably wherein the therapeutic agent is an antigen binding protein. Methods of treatment comprising use of said agent are also disclosed.