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3101 results about "Metabolism" patented technology

Metabolism (/məˈtæbəlɪzəm/, from Greek: μεταβολή metabolē, "change") is the set of life-sustaining chemical reactions in organisms. The three main purposes of metabolism are: the conversion of food to energy to run cellular processes; the conversion of food/fuel to building blocks for proteins, lipids, nucleic acids, and some carbohydrates; and the elimination of nitrogenous wastes. These enzyme-catalyzed reactions allow organisms to grow and reproduce, maintain their structures, and respond to their environments. (The word metabolism can also refer to the sum of all chemical reactions that occur in living organisms, including digestion and the transport of substances into and between different cells, in which case the above described set of reactions within the cells is called intermediary metabolism or intermediate metabolism).

Method for in vitro slow release performance evaluation of slow and controlled release preparation based on overflow principle

The invention discloses a method for in vitro slow release performance evaluation of a slow and controlled release preparation based on the overflow principle. A container with an upper outlet and a lower outlet is adopted to serve as a release tank, a to-be-detected medicine and a dissolution medium are placed in the release tank, a stirring device is adopted in the release tank to perform stirring, and the dissolution medium is added from the lower outlet of the release tank through a peristaltic pump; the dissolution medium dissolved with the medicine is taken away through the overflow from the upper outlet so as to offset medicine absorption or metabolism, and the slow and controlled release speed of the medicine, the total medicine overflow quantity and the total release amount are calculated by measuring the concentration of the medicine contained in the dissolution medium flowing out, the volume of the release tank and the overflow quantity. According to the method, the releasing degree of the slow and controlled release medicine can be evaluated accurately, the effective medicine release time of the slow and controlled release preparation is evaluated, and slow release performances of the slow and controlled release preparation are evaluated comprehensively.
Owner:CHONGQING UNIV OF TECH

Abnormal monitoring method and system for immune cell culture

The invention discloses an abnormal monitoring method and system for immune cell culture. The method comprises the following steps: collecting cell physical state parameters, culture environment parameters and metabolic biochemical indexes in a culture system in real time; performing motility rate threshold judgment and morphological analysis based on the cell physical state parameters to generate a first abnormal signal; performing dynamic trend analysis on the metabolism biochemical indexes to generate a second abnormal signal; performing grade association on the culture environment parameters, the first abnormal signal and the second abnormal signal, and outputting a monitoring abnormal grade; and performing grading response construction according to the monitoring abnormity grade to obtain an abnormity monitoring report. According to the method, the pollution diffusion risk and the functional cell failure misjudgment rate can be reduced.
Owner:LANGTIAN BIOTECHNOLOGY (SHENZHEN) CO LTD

Reagent combination or kit for constructing intestinal organs and application of reagent combination or kit

The invention belongs to the technical field of biology, and discloses a reagent combination or kit for constructing intestinal organs and application of the reagent combination or kit. According to the reagent combination or the kit, intestinal organs can be obtained from cell-derived epithelial cells obtained from a donor in a non-invasive manner, and the obtained intestinal organs can be cryopreserved and recovered and can be amplified in vitro for a long time; transcriptome characteristics are similar to those of real human small intestine tissues, and typical marker genes of various small intestine pedigree cell types are highly expressed; compared with intestinal organs obtained through induction of pluripotent stem cells, the intestinal organs have more intestinal pedigree characteristics, and the intestinal function development is more mature; after being promoted to be mature, the intestinal organ also highly expresses genes related to drug absorption and metabolism, has drug absorption capability similar to that of an immortalized intestinal cell line, but more prominently shows intestinal cell lineage characteristics, is closer to an intestinal environment in a real human body, and can be used for screening intestinal disease drugs; the intestinal barrier function is realized.
Owner:GUANGZHOU NAT LAB

Intelligent root temperature regulation and control system for hydroponic crops and implementation method of intelligent root temperature regulation and control system

The invention relates to the technical field of temperature regulation, in particular to an intelligent root temperature regulation system for hydroponic crops and an implementation method thereof, and the system comprises a root system oxygen consumption monitoring module, an osmotic pressure state monitoring module, a root system metabolism state analysis module, a root temperature parameter reconstruction module and a nutrient solution circulation linkage module. According to the method, the metabolic rhythm state of the root system is judged through oxygen consumption rate gradient difference calculation and trend analysis, the cell injury risk is recognized through two-parameter logic judgment by combining the osmotic pressure change amplitude and the oxygen consumption trend, and the target root temperature is selected through gray correlation analysis according to the abnormal triggering temperature and the stable state temperature; a regulation and control instruction is generated, a PID algorithm is called in combination with real-time circulation flow velocity data to adjust the pump speed, closed-loop dynamic matching of a root temperature set value and a flow velocity behavior is achieved, the adaptability of root temperature response is enhanced, the real-time regulation and control capacity for metabolic imbalance is improved, and the stability and the moisture and nutrient absorption efficiency of a water culture environment root system are effectively improved.
Owner:泉州医学高等专科学校

Recombinant escherichia coli with high yield of ergothioneine and method for preparing ergothioneine by using recombinant escherichia coli

The invention provides recombinant escherichia coli with high yield of ergothioneine and a method for preparing ergothioneine, the recombinant escherichia coli co-expresses ergothioneine anabolic enzymes Egt1 and Egt2, the methyltransferase structural domain of the Egt1 is derived from trichoderma reesei, mycobacterium smegmatis EgtD or rhizopus nigricans, and the methyltransferase structural domain of the Egt2 is derived from the trichoderma reesei, the mycobacterium smegmatis EgtD or the rhizopus nigricans. The histidine sulfoxide synthase structural domain is derived from trichoderma reesei, schizosaccharomyces pombe or rhizopus nigricans, and the Egt2 is derived from claviceps purpurea, neurospora crassa or aspergillus niger. After the recombinant escherichia coli obtained by screening is cultured for 68 hours in a 5L fermentation tank, the yield of ergothioneine can reach 5g / L or above; wherein after recombinant escherichia coli co-expressing Egt1 enzyme (the structural domain of methyltransferase is derived from mycobacterium smegmatis EgtD, and the structural domain of histidine sulfoxide synthase is derived from trichoderma reesei) and Egt2 enzyme (derived from neurospora crassa) are cultured in a 5L fermentation tank for 68 hours, the yield of ergothioneine can reach 8.7 g / L, and the production intensity reaches 127.9 mg / (L.h).
Owner:THE UNITED BIO-TECH (HENGQIN) CO LTD

Vitamin K2 composite micro-capsule system with stomach protection and intestine slow release functions as well as preparation method and application of vitamin K2 composite micro-capsule system

The invention discloses a vitamin K2 composite micro-capsule system with stomach protection and intestine slow release functions and a preparation method and application thereof, the vitamin K2 composite micro-capsule system with stomach protection and intestine slow release functions comprises three layers, namely a core layer, a middle layer and an outer layer from inside to outside in sequence; the core layer is formed by coating vitamin K2 with a zein-lac hydrophobic core, the middle layer is a pea protein-pectin electrostatic compound, and the outer layer is sodium alginate and chitosan double-network gel. The micro-capsule system provided by the invention can be tightly combined in a gastric acid environment after being orally taken, the release of active ingredients in the stomach is reduced, and then the micro-capsule system stays at intestinal mucosa for a long time and slowly releases contents, so that the functions of the micro-capsule system are slowly presented outside, the half-life period is prolonged, and the action effect is improved. Vitamin K2 directly or indirectly participates in and regulates various physiological processes related to health, and plays an important role in the aspects of maintaining bone health, preventing cardiovascular diseases, protecting nerves, improving metabolism and the like.
Owner:WANG SHUHE (WUHAN) BIOTECHNOLOGY ENGINEERING CO LTD

Application of bifidobacterium animalis subsp. Lactis CP-9 in preparation of product for promoting bone growth and development or improving bone health

The invention provides an application of bifidobacterium animalis subsp. Lactis CP-9 in preparation of a product for promoting bone growth and development or improving bone health. Long-term research and a large number of experiments show that the bifidobacterium animalis subsp. Lactis CP-9 can improve the bone volume fraction, the bone trabecula thickness, the bone density and the bone volume of an organism, and can also effectively improve the growth hormone level and the insulin-like growth factor 1 level, so that bone growth and development are promoted. Meanwhile, the bifidobacterium animalis subsp. Lactis CP-9 can effectively improve the N-terminal propeptide level, osteocalcin level, bone morphogenetic protein level and osteoprotectin level of I-type procollagen in a body, and remarkably reduce the amino-terminal peptide level of the I-type collagen and the ligand level of nuclear factor kappa B receptor activating factor, so that osteoblast differentiation is promoted, osteoclast differentiation is inhibited, and osteoclast differentiation is inhibited. Furthermore, bone formation is promoted, bone resorption is inhibited, bone metabolism is improved, and finally the effect of improving bone health is achieved.
Owner:AUSNUTRIA DAIRY CHINA +1

Method for repairing soil heavy metal pollution by coupling soybean urease with biochar cementing agent

The invention discloses a method for restoring soil heavy metal pollution by coupling soybean urease with a charcoal cementing agent, and relates to the technical field of soil heavy metal pollution restoration, and the method comprises the following steps: dynamic microbiome regulation and control: introducing photosensitive protein into soil functional bacteria; the acyl homoserine lactone analogue is synthesized and applied to soil, and is competitively combined with a microbial quorum sensing receptor to block an inhibitor to secrete a signal channel; according to the method, microbial urease secretion is regulated and controlled through optogenetics, an inhibitor signal is blocked through quorum sensing interference, and a microbiome is precisely regulated and controlled; the pH-responsive nanocapsule releases an inhibitor in a targeted manner, and the magnetic-responsive nanochain dynamically captures interfering bacteria, so that the limitation of passive adsorption is broken through; the gene editing plant releases coumarin to inhibit fungal metabolism, and the engineering mycorrhizal fungi physically shields an inhibitor to construct cross-biosphere cooperative defense; the urease activity and the heavy metal removal rate are remarkably improved, meanwhile, the soil microbial diversity is maintained, and the soil specificity interference problem is solved.
Owner:GUANGDONG OCEAN UNIVERSITY

Hemodialysis on-line monitoring system and method

InactiveCN120242208ADialysis systemsSensorsSerum ironErythroid cell
The invention relates to the technical field of hemodialysis monitoring, and provides a hemodialysis on-line monitoring system and method, and the system comprises a data acquisition module which is used for collecting blood physiological parameters in a dialysis pipeline in real time; the blood component analysis module is connected with a blood loop of the dialysis machine and is used for detecting serum iron, ferritin and ferritin saturation indexes on line; and the data processing module is used for calculating the risk index of anemia, evaluating the iron utilization rate, constructing a model for measuring the iron deficiency erythropoiesis trend according to the collected and analyzed data, and training and optimizing the model. According to the method, individual parameters of patients are fused, personalized calculation is performed for iron metabolism rates and dialysis parameters of different patients, and data such as iron content, blood flow and dialysis fluid volume are acquired online in real time, so that iron concentration and infusion rate are accurately matched with real-time iron metabolism requirements of the patients, and anemia of the patients in the dialysis process is reduced.
Owner:THE SECOND HOSPITAL AFFILIATED TO WENZHOU MEDICAL COLLEGE

Biological preparation for improving quality of weever and application

The invention relates to a biological preparation for improving quality of weever, the biological preparation comprises an injection and an edible agent, the injection comprises chemically modified chemically synthesized single-stranded small RNA, Rev-erbalpha protein and Per1 protein, and the edible agent comprises Clock core peptide 1, Clock core peptide 2 and taurine. Skeletal muscle development, liver lipid metabolism and generation of cell inflammatory factors of the weever are influenced by adding and injecting the feed, so that the quality of the weever is improved, intramuscular fat deposition is promoted, the taste and flavor of fish meat are improved, the energy reserve of the weever can be improved, and the culture cycle is shortened. The improvement of cell inflammatory factors shows that the disease resistance of the weever is improved, the survival rate in the breeding process is further improved, and the use amount of antibiotics is reduced. The method provides an important theoretical basis for improving fish meat quality in China and promoting high-quality, efficient and healthy development of aquaculture, and has a wide market prospect.
Owner:CHANGSHA UNIVERSITY

Application of HERP gene knockout mouse model in obesity and metabolic disorder diseases

The invention discloses an application of an HERP gene knockout mouse model in obesity and metabolic disorder diseases. The invention finds that compared with a wild type high-fat group, HERP gene knockout can cause phenotypes such as early obesity, more serious obesity degree, increase of fat weight ratio, aggravation of adipose tissue inflammation, dyslipidemia and glucose metabolism disorder of mice during high-fat feeding. And the HERP gene is knocked out, so that the adipocyte differentiation is increased. The HERP gene knockout mouse is more sensitive to nutrition, obesity can occur more quickly during high-fat feeding, symptoms such as fat amplification, fat inflammation and glucose and lipid metabolism disorder are more serious, and the HERP gene knockout mouse can be used for molecular mechanism research and drug screening of obesity, fat tissue and glucose and lipid metabolism disorder. It is further found that cilostazol can significantly relieve mouse obesity and lipid metabolism disorder caused by HERP gene defects, but has no obvious weight losing effect on normal genotype mice, and a new strategy is provided for precise treatment.
Owner:THE FIFTH AFFILIATED HOSPITAL SUN YAT SEN UNIV

Morchella esculenta fruit forest intercropping system nutrient circulation intelligent regulation and control method based on Internet of Things

The invention discloses an intelligent nutrient circulation regulation and control method for a morchella esculenta fruit forest intercropping system based on the Internet of Things, particularly relates to the technical field of intelligent agriculture, and is used for solving the problem of symbiosis imbalance of hyphae and fruit trees caused by nutrient regulation and control lag and static threshold setting in the prior art. Hypha density, electric signal dominant frequency and root system absorption rate data are collected in real time through a multispectral impedance sensor and an ion selective electrode array, and a space-time aligned dynamic matrix is constructed; dynamically updating a nutrient balance threshold value based on a real-time ratio of a hypha metabolism rate to an absorption rate, and generating a nutrient transfer priority by combining collaborative analysis of a hypha transfer direction included angle and an electric signal main frequency offset gradient; a continuous transfer path is identified through a region growing algorithm, water and fertilizer amounts are distributed according to priorities, and a local area instruction is generated; and inverting the equipment response delay by using the high-frequency pulse signal, synchronously adjusting the execution frequency and updating the dynamic matrix and the threshold parameter, thereby realizing the dynamic adaptation and autonomous optimization of the nutrient supply and demand of the intercropping system.
Owner:TIANSHUI NORMAL UNIV

Rice field soil recarburization and capacity expansion method based on biochar-based organic fertilizer

ActiveCN120548812ABio-organic fraction processingMicroorganism based treatmentPaddy soilsAgricultural productivity
The invention relates to the technical field of soil function improvement, in particular to a rice field soil recarburization and capacity expansion method based on a charcoal-based organic fertilizer. The method comprises the following steps: crushing a biomass raw material, pyrolyzing and cooling to obtain biochar; immersing the biochar in a functional bacteria solution containing actinomycetes and bacillus for activating treatment to obtain modified biochar; mixing the modified biochar and decomposed straw, composting and fermenting to obtain organic fertilizers with different particle sizes; the large-particle-size organic fertilizer is applied to deep soil, the soil is covered with soil after straw is laid on the soil, and the small-particle-size organic fertilizer is applied to surface soil. Through layered application, the large-particle-size biochar repairs the deep soil structure and expands the carbon storage capacity, and meanwhile, the carbon stability is improved through carbon-nitrogen synergistic metabolism driven by functional bacteria, so that the carbon immobilization efficiency is improved, meanwhile, soil recarburization and expansion are achieved, the contradiction between carbon sequestration and structure degradation and nutrient imbalance in a traditional recarburization and expansion technology is solved, and the soil recarburization and expansion efficiency is improved. Synergic improvement of a carbon sink function and agricultural productivity is promoted.
Owner:NORTHEAST INST OF GEOGRAPHY & AGRIECOLOGY C A S

Solid waste admixture prepared based on microbiological treatment regenerated micro powder and preparation method

The invention discloses a solid waste admixture prepared based on microbiological treatment of regenerated micro-powder and a preparation method, and aims to overcome the defect that the dilution effect is remarkable when regenerated micro-powder is directly used as an admixture in the prior art. The method comprises the following steps: treating waste concrete to obtain regenerated micro powder; culturing bacillus pasteurii, and preparing a bacterial solution with a target OD value; mixing the regenerated micro-powder and a bacterial solution according to a certain solid-to-liquid ratio, adding urea and biochar, and reacting in a magnetic stirrer for a set time to obtain modified regenerated micro-powder; and taking out the modified regenerated micro powder, filtering, drying to constant weight, and fully scattering to obtain the solid waste admixture. According to the present invention, the bacteria-containing culture solution is subjected to centrifugal treatment and the low concentration of the bacteria solution is adopted, such that the by-products generated by the metabolism of the bacillus pasteurii are reduced on the premise of ensuring the sufficient decomposition of the urea, and the prepared regenerated micro-powder contains rich ultrafine calcium carbonate on the surface, and can be adopted as the solid waste admixture to significantly enhance the compressive strength of the cement matrix.
Owner:CHANGAN UNIV

Method and system for monitoring operation state of constructed wetland

The invention relates to the technical field of water, waste water, sewage or sludge treatment, and particularly provides a constructed wetland operation state monitoring method and system.The method comprises the steps that based on a distributed sensing node array, water flow permeation rates, medium temperature gradients and dissolved matter concentration distribution of different depths and areas of a constructed wetland are collected in real time; generating a three-dimensional dynamic thermodynamic-substance diffusion map; extracting an actual flux difference value of an input-output cross section, and calculating the deviation degree between the current actual load and the theoretical purification capacity by combining the actual flux difference value with the historical adsorption capacity of the wetland medium; and integrating the historical load data with a current early warning report corresponding to the deviation degree, constructing a medium metabolism efficiency attenuation curve, predicting the saturation adsorption periods of matrixes in different regions, and reversely deducing an optimal maintenance node. The system comprises a map generation module, a deviation degree calculation module and a period prediction module. According to the method, discrete physical-chemical-biological process parameters are converted into a continuous decision flow through a space-time coupling model.
Owner:PINGLIANG ECOLOGICAL ENVIRONMENT MONITORING CENT OF GANSU PROVINCE

Intelligent weight loss dynamic matching intervention method and decision-making system for obese patients in hospital based on multi-modal data fusion

The invention discloses a hospital obese patient intelligent weight loss dynamic matching intervention method and decision making system based on multi-modal data fusion, and relates to the field of medical health, and the method comprises the following steps: S1, carrying out the real-time collection and fusion of multi-modal data; s2, dynamic metabolism modeling and plateau period breakthrough; s3, generating a hierarchical intervention strategy; s4, performing psychological-physiological linkage intervention; and S5, performing real-time safety control and feedback optimization. By collecting multi-dimensional data, constructing the model, accurately predicting the metabolic rate, the metabolic plateau period and the sudden eating tendency, dynamically adjusting the exercise intensity and the diet scheme according to the conditions of different patients, triggering a low-intensity exercise mode for the obese patients with cardiac insufficiency and calibrating diet, ensuring the exercise safety, and improving the exercise efficiency. Operation suggestions are generated on the basis of the standard, precise preoperative evaluation is conducted, postoperative rehabilitation is optimized in combination with nerve stimulation data, dangerous postures are monitored, the sport injury risk is reduced, and personalized, safe and efficient intelligent weight reduction intervention for obese patients is achieved.
Owner:KUNSHAN FIRST PEOPLES HOSPITAL

Enterococcus pluvialis capable of effectively regulating uric acid metabolism as well as fungicide and application of enterococcus pluvialis

PendingCN120424822ABacteriaAnimal feeding stuffInflammatory factorsUrate/Creatinine
The invention discloses an intestinal strain capable of effectively regulating uric acid metabolism, a microbial agent of the intestinal strain and application of the intestinal strain in uric acid reducing products, and belongs to the technical field of microorganisms. According to the enterococcus pluvialis ZQ205, the enterococcus pluvialis ZQ205 which is free of toxic and side effects and capable of effectively relieving and treating the hyperuricemia is found for the first time, and the collection number of the enterococcus pluvialis ZQ205 in the China Center for Type Culture Collection is CCTCC NO: M 2025844; the strain can significantly reduce the levels of uric acid, creatinine and urea nitrogen in serum of mice, can effectively reduce the levels of inflammatory factors such as IL-6 and TNF-alpha in serum of hyperuricemia mice, and can improve kidney injury caused by hyperuricemia.
Owner:FARM PROD PROCESSING & NUCLEAR AGRI TECH INST HUBEI ACAD OF AGRI SCI

Fungus extract for effectively regulating uric acid metabolism and relieving inflammation and application of fungus extract in reducing uric acid

The invention discloses a fungus extract capable of effectively regulating uric acid metabolism and relieving inflammation as well as a preparation method and application of the fungus extract, and belongs to the technical field of deep processing of edible fungi. Schizophyllumcommuneh and poplar phellinus sporocarp are mixed and extracted, and the prepared fungus extract can effectively inhibit activity of xanthine oxidase in serum and liver of mice, reduce content of uric acid, creatinine, urea nitrogen and the like in serum and promote excretion of uric acid, creatinine, urea nitrogen and the like in urine; meanwhile, the content of inflammatory markers such as IL-6 and TNF-alpha in mouse serum can be effectively reduced, inflammatory infiltration of liver and kidney cells is relieved, and the problem that an existing edible mushroom extract is not ideal in treatment effect on hyperuricemia is solved.
Owner:FARM PROD PROCESSING & NUCLEAR AGRI TECH INST HUBEI ACAD OF AGRI SCI

Whitening and freckle-removing composition containing composite plant extract and preparation method of whitening and freckle-removing composition

The invention relates to a whitening and freckle-removing composition containing a composite plant extract and a preparation method of the whitening and freckle-removing composition, and belongs to the technical field of cosmetics. The composition disclosed by the invention is prepared from the following raw materials in parts by weight: 5 to 8 parts of pineapple leaf nano cellulose, 10 to 16 parts of modified starch, 10 to 15 parts of longan seed extract, 6 to 10 parts of mulberry bark extract, 5 to 8 parts of nicotinamide and 8 to 10 parts of hyaluronic acid. The pineapple leaf nanocellulose contains flavonoid and phenolic compounds with double-bond, conjugated double-bond and triple-bond structures, and modified starch is used as a filler to form a film on the surface of skin, so that an anti-ultraviolet protection wall is formed; the betaine-malate ionic liquid is added into the longan seeds, so that extraction of polyphenol in the longan seeds is improved, the longan seeds have acid-base buffering capacity, an auxiliary does not need to be added to adjust the pH value, the components of the prepared composition interact, and the whitening and freckle removing effects are achieved from multiple aspects of ultraviolet resistance, oxidation resistance, inflammation resistance and skin metabolism improvement.
Owner:GUANGZHOU QIAOZIYAN COSMETICS CO LTD

Phellinus igniarius mycelium fermentation product as well as preparation method and application thereof

The invention relates to a phellinus igniarius mycelium fermentation product and a preparation method and application thereof, and the preparation method comprises the following steps: inoculating a phellinus igniarius mycelium seed solution into a sterile fermentation culture medium for culturing, carrying out solid-liquid separation, filtering a clear liquid through a membrane and sterilizing to obtain the phellinus igniarius mycelium fermentation product, the fermentation medium comprises the following components: a beet extract, a deep eutectic solvent and water. The beet extract and the deep-eutectic solvent are creatively adopted as culture medium components to prepare the phellinus igniarius mycelium fermentation product, the beet extract and the deep-eutectic solvent jointly provide nutrients needed by phellinus igniarius fermentation, meanwhile, the deep-eutectic solvent is used for regulating metabolism, and compared with a product obtained through fermentation of a traditional culture medium, the phellinus igniarius mycelium fermentation product has the advantages that the fermentation efficiency is high; the content of active ingredients in a fermentation product obtained by adopting the culture medium with the formula is remarkably increased, and the fermentation product is good in uniformity and high in stability, is a clear liquid in appearance, has no abnormal odor and has slight phellinus igniarius characteristic odor.
Owner:SHE LOG (GUANGZHOU) BIOTECHNOLOGY CO LTD

Application of hispidulin in preparation of lipid de novo synthesis inhibitor or metabolism-related fatty liver disease treatment or prevention product

The invention relates to the field of biological medicine, in particular to application of hispidulin in preparation of a lipid de novo synthesis inhibitor or a metabolism-related fatty liver disease treatment or prevention product. The hispidulin disclosed by the invention has a chemical structure as shown in a formula (I). The hispidulin in the invention reverses liver cell lipid droplet excessive infiltration induced by high-dose fructose in a dose-dependent manner; furthermore, the hispidulin dose-dependent ameliorating obesity signs in HFD-induced MAFLD model mice, including liver weight, body weight, blood lipid level, liver fat content, and insulin resistance, without significantly reducing food intake.
Owner:SHANGHAI SEVENTH PEOPLES HOSPITAL

Blood sugar reducing egg production monitoring method and system based on fermented feed

The invention relates to the technical field of production monitoring control, and discloses a method and a system for monitoring production of eggs capable of reducing blood sugar based on fermented feed. The method comprises the following steps: detecting the hypoglycemic active components of the fermented feed through a multispectral sensor array to obtain spectral characteristic data; establishing a laying hen blood glucose metabolism correlation model by using a partial least squares regression algorithm; dynamically predicting the egg hypoglycemic index based on the incidence matrix and performing function grading; regulating and controlling formula parameters of the fermented feed in real time by adopting a particle swarm optimization algorithm; and carrying out production process quality tracing monitoring and abnormity early warning according to the optimized formula instruction. According to the method, the monitoring precision, the prediction accuracy and the quality stability of the production of the blood-sugar-reducing eggs are improved.
Owner:BEIJING ZHONGKE SINO BIOTECHNOLOGY CO LTD

Computer simulation and regulation method and system for beef cattle fat metabolism

The invention belongs to the technical field of bioinformatics, particularly relates to a computer simulation and regulation method and system for beef cattle fat metabolism, and aims to solve the problems of excessive fat deposition, low feed conversion efficiency, difficulty in multi-objective optimization and the like in existing beef cattle breeding. A multi-scale biological network model is constructed, a computer simulation and prediction engine is developed, an intelligent intervention strategy optimization engine is designed, and implementation and feedback optimization are carried out. By reducing unnecessary fat deposition, improving the feed conversion efficiency and improving the beef quality, the economic benefit of beef cattle breeding is remarkably improved, the requirements of consumers for high-quality and safe beef products are met, and the method has important value for promoting intelligent upgrading and sustainable development of the beef cattle industry.
Owner:XICHANG COLLEGE

Intelligent monitoring method for material components in composting fermentation process

The invention relates to the technical field of component monitoring, and discloses a compost fermentation process material component intelligent monitoring method comprising the following steps: collecting compost process environment data and compost process material component data in a compost process, and carrying out thermophilic bacteria metabolic activity on-line prediction to obtain a flora metabolic activity index; receiving the composting process environment data, the composting process material component data and the flora metabolism activity index by using the lightweight material component inversion model, and generating an optimal material component ratio; and comprehensively adjusting the material components in the composting fermentation process by using the optimal material component ratio. According to the method, environmental data and material component data in the composting process are collected in real time, the metabolic activity index of thermophilic bacteria is predicted on line, the optimal material component proportion is generated on the basis of a lightweight material component inversion model in combination with the environmental data, the material component data and the metabolic activity index, and the material components in the composting fermentation process are comprehensively adjusted, so that the composting fermentation efficiency is improved. Therefore, the composting effect is optimized.
Owner:GUANGXI FORESTRY RES INST

Smart multidosing

ActiveUS12347538B2Medical data miningDrug and medicationsAlternative treatmentDrug dosing
A method and algorithm for dosing single and multiple drugs for an individual patient includes the step of collecting data from the individual patient. The data includes drugs to be taken by the patient, the patient's age, medical condition, metabolism, and other factors. The method further includes the steps of analyzing the individual patient data in view of dosing criteria established based on patient population data. Based on the analysis, a dose of the single or multiple drugs is recommended. Alternative treatment options can also be recommended.
Owner:OPTIMDOSING LLC

Intelligent food recommendation and diet optimization system based on body temperature change

The invention relates to the technical field of health management, and discloses an intelligent food recommendation and diet optimization system based on body temperature change, and the system comprises a body temperature dynamic fluctuation curve generation module which collects data in real time through a multi-source temperature sensor of wearable equipment, and is used for generating a body temperature dynamic fluctuation curve; the metabolism state label acquisition module is used for matching the time-frequency domain characteristics with a preset metabolism mode library so as to acquire corresponding metabolism state labels; the calculation module is used for calling nutrient element intake records in the historical diet database of the user and a preset health target and is used for calculating a current metabolic rate deviation value and a nutrition gap; the diet scheme generation module is used for generating a suggested diet scheme containing a recommendation priority score and a real-time eating suggestion based on the metabolic rate deviation value, the nutrition gap and a preset health target; and the monitoring module is used for monitoring body temperature change data after the user executes the recommended diet scheme. The accuracy of health management can be improved.
Owner:SHENZHEN CEO TRADING CO LTD

Clostridium cadaverum strain and application thereof

The invention discloses a clostridium corpse strain and application thereof. The preservation number of the clostridium cadaveris J038 strain of the clostridium cadaveris J038 strain is CGMCC (China General Microbiological Culture Collection Center) NO. 35440, and the clostridium cadaveris J038 strain of the clostridium The clostridium corpse J038 strain is separated from pig manure for the first time, and 4-hydroxyphenylpropionic acid is produced by metabolism of the clostridium corpse J038 strain. In addition, the invention further provides application of the clostridium corpse in preparation of 4-hydroxyphenylpropionic acid, and when the clostridium corpse is adopted to prepare 4-hydroxyphenylpropionic acid, the clostridium corpse has the advantages of being small in environmental pollution, high in sustainability, precise, green, efficient and the like; the yield is high, and the increasing requirements of the fields of medicine, food, agriculture and the like on the 4-hydroxyphenylpropionic acid can be met.
Owner:MAIYUAN LABORATORY

Electric flocculation reactor and electric flocculation treatment method

The invention relates to an electric flocculation reactor and an electric flocculation treatment method. The electric flocculation reactor is provided with a biochemical treatment unit and a pretreatment unit located in the front of the biochemical treatment unit, and an electrode assembly with adjustable electrode spacing is arranged in the pretreatment unit. According to the electric flocculation treatment method, the electric flocculation reactor is adopted for removing pollutants in water, the distance between electrode plates in the electrode assembly is set or adjusted according to the water flow of inlet water or the pollutant flow, the biochemical treatment unit comprises an aerobic tank, the electrode assembly is arranged in the aerobic tank, iron ions are released through the electrode assembly, and the water quality is improved. And an iron ion environment beneficial to growth and metabolism of aerobic microorganisms is formed. According to the invention, the electrode spacing of the electric flocculation reaction can be adjusted, and the electric flocculation reaction device can better adapt to actual requirements.
Owner:BEIJING HEHAIQINGYUAN ENVIRONMENTAL PROTECTION SCI & TECH CO LTD

Antimony detoxification synergistic autotrophic nitrogen fixation pseudomonas and application thereof

The invention discloses a pseudomonas for antimony detoxification and autotrophic nitrogen fixation and application of the pseudomonas. The strain is separated from the rhizosphere of a pioneer plant in antimony-polluted soil of a tin mine in cold water river city, Hunan province, and is identified to be capable of quickly oxidizing high-toxicity antimony (III) into low-toxicity antimony (V) through autotrophic metabolism in a high-antimony environment, so that antimony detoxification is realized, and the detoxification rate is 108.6 (mu mol / (L.day)). The strain has autotrophic nitrogen fixation activity and can achieve autotrophic growth under the oligotrophic condition of a mining area, and the nitrogenase activity is larger than or equal to 223.4 (nmol C2H2 / (g.h)). Particularly, the antimony detoxification and nitrogen fixation capabilities of the strain have a synergistic effect, so that the strain has unique advantages in the field of heavy metal antimony pollution remediation, and dual effects of antimony pollution treatment and soil improvement can be synchronously realized; the development and application prospects are good.
Owner:CENT SOUTH UNIV

Composite acid gel for nursing scalp and preparation method thereof

The invention belongs to the technical field of hair care products, and particularly relates to composite acid gel for scalp care and a preparation method thereof. Salicylic acid, glycolic acid, piroctone azelate olamine salt, echinacea purpurea-lactic acid bacteria yeast, an emulsifier and water are combined, wherein the echinacea purpurea-lactic acid bacteria yeast is prepared by performing enzymolysis on echinacea purpurea through bacillus subtilis protease and then performing aerobic fermentation with lactic acid bacteria. Salicylic acid, glycolic acid and azelaic acid in the composite acid gel are compounded, so that stimulation of salicylic acid is weakened, and the effect of dissolving hair follicle grease is reserved; glycolic acid and azelaic acid are added to accelerate keratin metabolism, regulate sebum secretion and create safe and healthy shielding for the scalp environment, and polysaccharide and flavonoid compounds in the echinacea purpurea-lactic acid bacteria leavening are beneficial to exerting the anti-oxidation and immune regulation effects of the echinacea purpurea-lactic acid bacteria leavening. Therefore, the composite acid gel provided by the invention is green, safe and non-irritant, the preparation method is simple and convenient, and the composite acid gel can be used for inhibiting bacteria and reducing scalp inflammation.
Owner:CHAYAN BIOTECHNOLOGY CO LTD