1964 results about "Sulfoxide" patented technology

A composition and method for performing a polynucleotide amplification reaction at low temperature, including a polynucleotide amplification reaction mixture into which is incorporated a sufficiently high concentration of a low molecular weight compound selected from the group consisting of amides, sulfones, sulfoxides and diols, to accomplish the amplification at the low temperature. In another embodiment, a composition and method for enhancing a polynucleotide amplification reaction, including a polynucleotide amplification reaction mixture into which is incorporated a low molecular weight diol in an amount effective to enhance the polynucleotide amplification.

A process for the removal of organosulfur compounds from hydrocarbon materials is disclosed. The process includes contacting an ionic liquid with a hydrocarbon material to extract sulfur-containing compounds into the ionic liquid. The sulfur-containing compounds can be partially oxidized to sulfoxides and/or sulfones prior to or during the extraction step.

A method for functionalizing the wall of single-wall or multi-wall carbon nanotubes involves the use of acyl peroxides to generate carbon-centered free radicals. The method allows for the chemical attachment of a variety of functional groups to the wall or end cap of carbon nanotubes through covalent carbon bonds without destroying the wall or endcap structure of the nanotube. Carbon-centered radicals generated from acyl peroxides can have terminal functional groups that provide sites for further reaction with other compounds. Organic groups with terminal carboxylic acid functionality can be converted to an acyl chloride and further reacted with an amine to form an amide or with a diamine to form an amide with terminal amine. The reactive functional groups attached to the nanotubes provide improved solvent dispersibility and provide reaction sites for monomers for incorporation in polymer structures. The nanotubes can also be functionalized by generating free radicals from organic sulfoxides.

The invention relates to an organic optoelectronic material, a preparation method of the organic optoelectronic material and an organic light emitting diode containing the organic material. The material is shown in the formula I, wherein R1 and R2 are respectively and independently hydrogen, halogen, cyanogroup, nitryl, isothiocyano, sulfonyl, sulfuryl, acylamino, alkyl of which the carbon atom number is 1 to 10 or alkoxy of which the carbon atom number is 1 to 12; A1 and A2 are respectively and independently phenyl, polycyclic conjugate aryl of which the carbon atom number is 10 to 60 or aromatic heterocyclic group containing at least one of N, S and O; two phenyls having groups R1 and R2 and two para-positions relative to the groups R1 and R2 are connected by directly bonding or connected through X; A1 is connected with A2 by directly bonding or through Y; X and Y are respectively and independently sulphur, oxygen, alkylene of which the carbon atom number is 1 to 6 or alkenyl of which the carbon atom number is 2 to 6; Ar1 and Ar2 are respectively and independently phenyl, cyanophenyl, alkyl benzene, polycyclic conjugate aryl of which the carbon atom number is 10 to 60 or aromatic heterocyclic group containing at least one of N, S and O.

The present invention relates to, inter alia, a composition for stripping photoresist from substrates comprising: about 5% to about 50% by weight of an alkyl substituted pyrrolidone, an alkyl substituted piperidone, or a mixture thereof, about 0.2% to about 20% of one or more alkanolamines, and about 50% to about 94% of a sulfoxide, sulfoxone, or mixture thereof. Advantageously, the composition can remove copper from a copper substrate at a rate of less than about 10 Å per minute when the substrate is immersed in the composition which is held at 70° C. for 30 minutes and rotated relative to the composition at about 200 revolutions per minute.

The present invention provides a transdermal formulation for the delivery of at least one active agent. The formulation includes (i) a first compound comprising an organic sulfoxide, and (ii) a second compound selected from the group consisting of a fatty acid ester, a fatty acid, an azone-related compound and mixtures thereof.

The invention discloses a new preparation method of 4,4-dichlorodiphenyl sulfone. The method comprises the following steps: 1) through using AlCl3 as a catalyst, and chlorobenzene and thionyl chloride as reaction raw materials, performing a Friedel-Crafts reaction at 25-35 DEG C, then hydrolyzing the mother liquor obtained through the Friedel-Crafts reaction, refluxing at 95-100 DEG C for 45-60 minutes, cooling the obtained mother liquor to less than 20 DEG C after refluxing to obtain an organic phase and an aqueous phase; 2) performing reduced pressure distillation on the organic phase, centrifuging, washing the obtained product to be neutral and be used as a product A for later use, wherein the main component of the product A is 4,4-dichlorodiphenyl sulfoxide; and 3) through using the product A and the oxidant hydrogen peroxide as raw materials and acetic acid as satalytic solvent, carrying out an oxidation reaction on the main component 4,4-dichlorodiphenyl sulfoxide of the product A to obtain crude 4,4-dichlorodiphenyl sulfone. Therefore, the existing synthesis method of 4,4-dichlorodiphenyl sulfone is changed, the production cost of 4,4-dichlorodiphenyl sulfone is low, the product quality is good and the reaction time is short.

The invention discloses a method for preparing 4.4-dichlorodiphenyl sulfone by using sulfoxide oxidation. The method comprises the following steps of: (1) performing Frieldel-Crafts reaction at the temperature of 25-35 DEG C by taking AlCl3 as a catalyst and chlorobenzene and thionyl chloride as reaction raw materials; next, hydrolyzing mother liquor after the Frieldel-Crafts reaction is finished; refluxing at the temperature of 95-100 DEG C for 45-60 minutes after hydrolysis is finished; cooling to be below 20 DEG C to divide into an organic phase and a water phase after refluxing is finished; performing reduced pressure distillation and centrifugal washing on the organic phase to be neutral to serve as a product A for later use, wherein a main component in the product A is 4.4-dichlorodiphenyl sulfone; and (2) performing oxidation reaction on the 4.4-dichlorodiphenyl sulfone by taking the product A as the raw material, hydrogen peroxide as a catalyst and dichloromethane as a reaction solvent to synthesize a 4.4-dichlorodiphenyl sulfone rough product. Thus, the method has the advantages of mild reaction conditions, high product quality and low three wastes (waste water, waste gas and industrial residues).

The present invention provides acetone complexes of sulfoxide compounds, useful as medicines such as inhibitors of gastric acid secretion and anti-ulcer agents or as intermediates for production of medicines, a process for producing the same and a purification method of using the same.Namely, it is the acetone complexes of sulfoxide compounds or of pharmaceutically acceptable salts thereof represented by the following formula:(wherein R1 represents a hydrogen atom, a methoxy group or a difluoromethoxy group, R2 represents a methyl group or a methoxy group, R3 represents a 3-methoxypropoxy group, a methoxy group or a 2,2,2-trifluoroethoxy group, R4 represents a hydrogen atom or a methyl group, n and m independently represent an integer of 1 to 4, and B represents a hydrogen atom, an alkali metal atom or ½ alkaline earth metal atom), which are obtained by treating the sulfoxide compounds or pharmaceutically acceptable salts thereof with acetone.

The invention discloses a preparation method for sulfoxide and sulphone. The preparation method comprises the following steps: conducting contact reaction on thioether and hydrogen peroxide, and catalyst in a fixed bed reactor, wherein the mole ratio of thioether and hydrogen peroxide is 1:0-1.5, the space velocity of the reaction system is 5-100, the reaction temperature ranges from normal temperature to 100 DEG C, the reaction pressure is 0.1-1.0 MPa, and the catalyst is obtained from one or more titaniferous molecular sieve raw powder or formed titaniferous molecular sieve. The method has the advantages of convenient operation, mild reaction conditions, easy separation, high product yield and the like, and the utilization rate of oxidant hydrogen peroxide can be greatly improved.

A process for making an aromatic aldehyde in which a sulfoxide is reacted with a dihalogenated aromatic compound in the absence of an effective amount of an activating reagent. The aldehyde may then be used to make other compounds, such as a compound that acts as a cPLA inhibitor.

The invention discloses a synthetic process for efficiently and continuously producing 4,4-dichlorodiphenyl sulfone, which comprises the following steps: carrying out Friedel-Crafts acylation on thionyl chloride and excessive chlorobenzene under the action of a lewis acid catalyst, carrying out pyrohydrolysis and adding chlorobenzene to carry out layering after the reaction is finished, adding anoxidizing agent into a sulfoxide organic layer to carry out oxidization, adding activated carbon to carry out decoloration and filtering; cooling filtrate and carrying out rejection filtration to obtain 4,4-dichlorodiphenyl sulfone. The synthetic process has the advantage that chlorobenzene not only is a raw material, but also is a reaction solvent, so that cross use of various solvents is avoided. Particularly, use of a great amount of acetic acid used as an oxidation reaction solvent is avoided, and corrosion to equipment and environmental pollution are avoided. In the integral process flow,separation and extraction of an intermediate 4,4-dichlorodiphenyl sulfoxide are avoided, so that production time of the product is greatly shortened, and production cost is saved. By using hydrogen peroxide, acetic acid and concentrated sulfuric acid as mixed oxidizing agents, oxidization capacity of hydrogen peroxide is greatly improved, yield and purity of the product are greatly improved, yield of the product reaches 90% or more, and purity of the product is greater than 99.8%.

A process for producing lyophilized competent cells wherein competent cells are that can be stored or shipped as freeze-dried cells at temperatures between 0° C. and 8° C. and remain suitable for cloning genes or DNA fragments. The process includes culturing cells, rending the cells competent, and lyophilizing the cells. Once lyophilized, the cells can be stored or shipped as freeze-dried cells. The lyophilized cells are prepared for transformation protocols by being re-hydrated in a solution of dimethyl sulfoxide. Once re-hydrated, the transformation efficiency of the competent cells is at least 5x105 transformations per microgram of DNA.

A compound comprising a poly(ether-thioether), poly(ether-sulfoxide) or poly(ether-sulfone) backbone bearing a plurality of ligands that are individually bound to chiral carbon atoms located within the backbone, at least one of the ligands including a moiety such as a naturally occurring nucleobase, a nucleobase binding group or a DNA interchelator; a process of synthesizing the compound, monomers to be used in this process and their synthesis process and processes for using the compound in biochemistry and medicine.

The present invention relates to a composition for coating an organic electrode and method of manufacturing an organic electrode having a excellent transparency using the composition comprising 3% to 20% by weight of a polyhydric alcohol, polyol or a mixture thereof, 5% to 10% by weight of a primary alcohol having C1 to C5, 5% to 25% by weight of a amide, sulfoxide or a mixed solvent thereof, 0.01% to 0.1% by weight of a surfactant and a aqueous solution of polyethylenedioxythiophene (PEDOT) conductive polymers having nano-sized particle in a remainder. The present invention indicates the excellent transparency that transmittance of organic conductive layer is more than 90% in the visible ray area and sheet resistance is 300 to 900 Ω/sq in case of coating. Therefore the present invention is capable of manufacturing the organic electrode such a electrode or a writing material of organic transistor, smart card, antenna, electrode of battery and fuel battery, capacitor using for PCB, inductor, electromagnetic wave cover and a sensor etc. as well as the transparency electrode using for display.

Processes for preparing sulfoxides useful as drugs such as acid secretion inhibitors or antiulcer drugs or intermediates for the preparation of drugs in high yields, at high purities, and with safety. Specifically, a process for the preparation of sulfoxides (II) by oxidizing a thio ether (I) with a peroxoborate salt in the presence of an acid anhydride or a metal catalyst; and a process for the preparation of sulfoxides (II) by oxidizing a thio ether (I) with an N-halosuccinimide, 1,3-dihalo-5,5-dimethyl-hydantoin or dichloroisocyanuric acid salt in the presence of a base. In said formulae R1 is hydrogen, methoxy or difluoromethoxy; R2 is methyl or methoxy; R3 is 3-methoxypropoxy, methoxy or 2,2,2-trifluoroethoxy; and R4 is hydrogen or methyl

A process for stereoselective synthesis of a compound of Formula (X) or Formula (X′)

• wherein R¹, R², and R³ are as defined herein, the process comprising: (a) reacting the starting material of formula A with a chiral sulfoxide anion source in a suitable solvent to prepare a compound of formula C or C′;
• (b) reducing the sulfoxide of formula C or C′ in a suitable solvent to obtain the compound of formula D or D¹; and (c) cyclizing the compound of formula D or D′ in a suitable solvent to form the epoxide compound of Formula (X) or Formula (X′), or a tautomer, prodrug, solvate, or salt thereof; pharmaceutical compositions containing such compounds, and methods of modulating the glucocorticoid receptor function and methods of treating disease-states or conditions mediated by the glucocorticoid receptor function or characterized by inflammatory, allergic, or proliferative processes in a patient using these compounds.

Compounds of the formula and quaternary ammonium ions thereof, wherein R1 and R2 are the same or different and are carbocyclic aryl or aromatic heterocyclic; A is methylene, carbonyl or sulfonyl; B is a single bond, C1-C4 alkylene or C2-C4, alkenylene; D is oxygen; E is C2 alkylene; G is C1-C4 alkylene or C2-C4 alkenylene; and L is -C(R4)(R5), wherein R4 and R5 together with the carbon atom to which they are attached represent a C5-C10 cycloalkyl or a C5-C10 heterocyclic. Especially preferred are compounds wherein L represents wherein J is a C1-C6 alkylene; Ar is a ring carbocyclic or aromatic heterocyclic and S*->O is a sulfoxide in which the sulfur atom is in the 5-configuration. The compounds have tachykinin receptor antagonist activity and exhibit an activity against both the NK1 and NK2 receptors.

A method for removing acidic gases from waste gases is disclosed. The invention relates to a method for removing acid gases, in particular from SO₂ and NO_x, by contacting the waste gas with an emulsion of water in organic sulfoxides, in particular of water in oil-derived-sulfoxides. The organic sulfoxide phase can be regenerated after the emulsion is loaded with polluants, by letting the emulsion to settle down and separate into two phases. The aqueous phase obtained after the separation contains sulfate and nitrate ions which can be collected and used as valuable chemicals.