7 results about "Leaving group" patented technology

The Invention relates to a method Method for making a ruthenium catalyst comprising the steps of - Providing an aromatic dithiol substituted on adjacent aromatic carbon atoms with thiol groups, wherein in a first step an aromatic compound substituted with two leaving groups on adjacent aromatic carbon atoms are reacted with alkali trithiocarbonate to obtain an aromatic benzodithiole-thione, which in a subsequent step is reacted / hydrolysed with a base; - providing a zinc dithiolate compound by reacting the aromatic dithiol with a zinc carboxylate in an organic solvent; Reacting the zinc dithiolate compound with a ruthenium compound wherein X1 and X2 are, independently of each other, are anionic ligands and are the same or different; L and L2 are, independently of each other, neutral electron donor ligands and are the same or different; Ar is an aromatic group which may be substituted and that can be bridged with L, if L is an alkoxy group; - Obtaining a ruthenium catalyst of formula 4 or 4a, wherein R1 to R4 are, independently of each other, are selected from hydrogen, halogen, alkyl, aryl, or R.1 with R3, R3 with R4 or R2 with R4 are forming together an aliphatic or aromatic ring.

This invention discloses a highly efficient oxygen removal reagent and its application in the deoxygenation reconstruction of carbon resource molecular skeletons, comprising a pivot reagent, a phosphine reagent, an azo reagent, a reducing agent, an acid reagent, a base reagent, a photosensitizer, and an organic solvent; wherein, X in the pivot reagent includes a hydrazine group or a sulfone group; PG is a protecting group; LG is a leaving group; by using natural oxygen-containing functional groups such as alcohols, aldehydes, and ketones as direct coupling precursors, an integrated in-situ activation-deoxygenation coupling process is achieved, significantly reducing reaction steps.

This invention provides a method for synthesizing liquid crystal compounds. This method uses dihaloalkanes and difluoromethane with leaving groups as raw materials to synthesize liquid crystal compounds while ensuring high yield and significantly reducing production costs.

The application discloses a kind of chiral ligand PPBOX, its preparation method and application in asymmetric catalytic conversion, specifically related to a kind of compound as shown in formula I as chiral ligand in reaction, the reaction is reaction A, reaction B or reaction C;Reaction A: copper catalyst catalyzed tension release driven remote leaving group participated asymmetric propargyl amination, reaction B: copper catalyst catalyzed tension release driven remote leaving group participated asymmetric alkylation reaction, reaction C: copper catalyst catalyzed asymmetric propargyl enoxy. Such chiral ligand has excellent catalytic efficiency and stereoselective effect in the three types of asymmetric conversion reactions.

This invention relates to the field of organic synthesis and discloses a method for the visible-light photocatalytic synthesis of 3-fluoroindole oxides. This method utilizes a benzothiazole-substituted sulfone group as the leaving group, achieving efficient preparation of 3-fluoro-3-alkyl-N-methylindole oxides with a fluorine-containing quaternary carbon center under excited-state photocatalytic redox conditions. Compared with traditional methods for synthesizing 3-fluoroindole oxides, this invention has the following advantages: convenient substrate preparation; mild reaction conditions; and good functional group compatibility.

The present application relates to a growth inhibitor for film formation, a film formation method using the same, and a semiconductor substrate manufactured thereby, and more particularly to a growth inhibitor for film formation which is a compound represented by Chemical Formula 1, a film formation method using the same, and a semiconductor substrate manufactured thereby, [Chemical Formula 1] AnB m X o Y i Z j wherein A is carbon or silicon; B is hydrogen or an alkyl group having 1 to 3 carbon atoms; X is a leaving group having a bond dissociation energy of 50 to 350 KJ / mol; Y and Z are each independently one or more selected from oxygen, nitrogen, sulfur, and fluorine and are different from each other; n is an integer of 1 to 15; o is an integer of 1 or more; m is 0 to 2n+1; and i and j are each an integer of 0 to 3. The present application can suppress side reactions, reduce film growth rate, and remove process by-products in the film, thereby greatly improving step coverage and thickness uniformity of the film even when forming a film on a substrate having a complex structure.

The application provides a preparation method of beta configuration deoxynucleoside, and belongs to the technical field of nucleoside synthesis. The application regulates the stereoselectivity of the reaction by limiting the combination of the type of organic solvent and the base catalyst: in the organic solvent environment, compound A mainly exists in the thermodynamically stable alpha configuration, the low dielectric constant of the solvent effectively inhibits the formation of carbonium ion and the competition of the SN1 path; the solvent has specific strong coordination with the alkali metal cation, successfully strips the anion in compound B, forms a very high nucleophilic activity 'naked anion', and assists positioning through the ion pair effect of the metal cation in the base catalyst; under the kinetic control, the nucleophilic nucleophilic salt species specifically attacks the leaving group of compound A through SN2 back attack, causes the Walden inversion of the chiral center, is converted into the beta configuration, and finally high-yield and high-stereoselective beta configuration deoxynucleoside is obtained.