1 results about "Single isomer" patented technology

The present application relates to a method for preparing (Z / E)-2- β -D-glucopyranosyloxy-4-methoxycinnamic acid geometric isomers from chamomile medicinal materials. The method takes chamomile medicinal materials as raw materials, extracts by refluxing with ethanol, concentrates and dries to obtain extract powder; then dissolves in methanol, centrifuges and filters, separates the soluble part by supercritical fluid chromatography to obtain target fraction rich in (Z / E)-2- β -D-glucopyranosyloxy-4-methoxycinnamic acid geometric isomers, purifies by semi-preparative liquid chromatography to obtain (Z / E)-2- β -D-glucopyranosyloxy-4-methoxycinnamic acid geometric isomers. The method has clear separation route and good repeatability, can realize effective preparation and separation of GMCA geometric isomers, and can provide material basis for structure confirmation, quality evaluation, in-vivo process research and related activity research. The method solves the problems of difficult separation and difficult obtaining of high-purity single isomer sample of (Z / E)-2- β -D-glucopyranosyloxy-4-methoxycinnamic acid (GMCA) geometric isomers in the prior art.