7135 results about "Imidazole" patented technology

The invention relates to a dialkyl imidazole bionic lipid compound and a preparation method and application thereof.The structure of the dialkyl imidazole bionic lipid compound imitates natural phospholipid design, alkyl with no less than 10 carbon atoms is modified on the fourth site and the fifth site of imidazole, and primary amines with different alkyl chain lengths are modified on the second site; the dialkyl imidazole bionic lipid compound is mixed with a therapeutic drug and other auxiliary materials to prepare lipid nanoparticles loaded with the therapeutic drug, and the lipid nanoparticles can be used as a drug delivery system for preparation of brain-targeted drugs. The dialkyl imidazole bionic lipid has the function of dynamically regulating and controlling the blood-brain barrier, and can realize reversible opening of the blood-brain barrier; the formed drug-loaded lipid composition can pass through a blood brain barrier and well realize brain-targeted delivery of loaded therapeutic drugs; the drug-loaded lipid composition composed of the dialkyl imidazole bionic lipid belongs to a new generation of bionic nano-drug carriers, and provides a new strategy for realizing brain-targeted delivery of different types of drugs.

The invention provides a method for enhancing interface bonding and corrosion resistance of a basalt fiber composite material, and belongs to the field of fiber surface modification chemical methods. The method is realized through the following steps: firstly, treating basalt fibers by utilizing an organic solvent through high-temperature reflux to prepare desized basalt fibers; then, the desized basalt fibers are immersed in a dopamine solution to be subjected to auto-polymerization, and basalt fibers with a polydopamine coating are prepared; sequentially immersing the basalt fiber coated with the polydopamine into a zinc salt solution and a 2-methylimidazole solution, so as to prepare a ZIF-8 modified basalt fiber; and finally, mixing the ZIF-8 modified basalt fiber with resin through electrostatic coating, and molding by adopting a segmented hot-pressing method to obtain the basalt fiber composite material. According to the method, a composite structure formed by the synergistic effect of a dopamine self-polymerization layer and ZIF-8 is introduced into the surface of the basalt fiber, so that the interface bonding force between the fiber and resin and the corrosion resistance of the composite material are greatly enhanced.

The invention provides a high-temperature-resistant and high-salt-resistant nano imbibition agent as well as a preparation method and application thereof. The high-temperature-resistant and high-salt-resistant nano imbibition agent is prepared from amination modified mesoporous silica nanoparticles, nano cellulose, rhamnolipid, an anionic surfactant, citrate modified sodium zirconium phosphate, polyethylene glycol-b-polycaprolactone and a sulfydryl-carboxyl imidazoline derivative, therefore, the composite carrier formed by the aminated mesoporous silica nanoparticles and the nanocellulose has high mechanical strength and uniform dispersity, the oil-water interfacial tension is reduced through the synergistic effect of the rhamnolipid and the anionic surfactant, and the crude oil stripping efficiency is remarkably improved; the citrate modified sodium zirconium phosphate enables the salt resistance of the system to be greatly improved, and in a high-temperature and high-salt oil reservoir environment, the nano imbibition agent can remarkably improve the crude oil recovery rate and reduce the injection pressure and dosage; meanwhile, good adsorption resistance is achieved, and reservoir blockage is prevented; in addition, low-toxicity corrosion inhibition components protect equipment, and the service life of an oil well is prolonged.

The invention relates to the technical field of adsorbents, and particularly discloses an aluminum oxide type adsorbent and a preparation method thereof.The preparation method comprises the following steps that lanthanum salt, cerium salt and a polyethylene glycol aqueous solution are mixed to be uniform, then the mixture is mixed with gamma-Al2O3 to be uniform, pH is adjusted, standing is conducted, solid-liquid separation is conducted, drying and roasting are conducted, and a double-doped carrier is obtained; dispersing the double-doped carrier in a mixed solution containing 2-methylimidazole, ferric salt and zinc salt, adjusting the pH value, carrying out heating reaction, solid-liquid separation and drying in an inert atmosphere, grinding to obtain powder, and carrying out molding treatment on the powder to obtain a composite carrier; uniformly mixing the Ag modified molecular sieve with silica sol, coating the surface of the composite carrier with the mixture, and drying to obtain an adsorbent precursor; dipping an adsorbent precursor in the dispersion liquid, and after dipping, solid-liquid separation and drying, reactivating to obtain the aluminum oxide type adsorbent; the prepared adsorbent can synergistically and efficiently remove multiple impurities and is excellent in corrosion resistance.

The invention provides a redox imidazole covalent organic framework material as well as a preparation method and application thereof, belongs to the technical field of material preparation and photocatalytic preparation of hydrogen peroxide, and aims to solve the technical problem of low activity of a current covalent organic framework in preparation of hydrogen peroxide. The preparation method of the imidazole-connected redox type imidazole covalent organic framework material comprises the following steps: respectively reacting a reactant 2, 7-di-tert-butylpyrene-4, 5, 9, 10-tetraketone monomer with 4, 4 ', 4', 4 ', 4', 4 ', 4', 4 ', 4', 4 ', 4', 4 ', 4', 4 ', 4', 4 ', 4', 4 ' The preparation method comprises the following steps: mixing 4, 4 '-(pyridine-2, 4, 6-triyl) tribenzaldehyde and a tri (4-formylphenyl) amine monomer, adding a solvent and a catalyst, uniformly stirring, and reacting to obtain the redox type imidazole covalent organic framework material after the reaction is finished. The application comprises the following steps: adding the covalent organic framework, oxygen and the sacrificial agent into water, and reacting under the irradiation of visible light. The preparation method is green, environment-friendly, simple and easy to implement, the prepared material has good thermal stability, and efficient visible light photocatalysis preparation of hydrogen peroxide can be achieved; meanwhile, the catalyst can be recycled and has good photocatalytic stability.

The invention discloses a scratch repair coating and a preparation method thereof, and relates to the technical field of high polymer materials. When the scratch repair coating is prepared, hydroxylated boron nitride reacts with 1-(3-triethoxysilylpropyl)-2-imidazoline to prepare pre-modified boron nitride, and then the pre-modified boron nitride and 4-chloro-1-butene are subjected to quaternization to prepare modified boron nitride; the preparation method comprises the following steps: reacting styryl phosphonic dichloride with 4, 4, 5, 5, 6, 6, 7, 7, 7-nonafluoro-1, 2-heptanediol to prepare a hydroxyl-terminated phosphorus-fluorine-containing polymer; the preparation method comprises the following steps: reacting isophorone diisocyanate with a hydroxyl-terminated phosphorus and fluorine-containing polymer to prepare a polyurethane prepolymer; reacting the polyurethane prepolymer with hydroxyl-terminated coumarin to generate modified polyurethane; and uniformly mixing the modified polyurethane, the modified boron nitride and a photoinitiator to prepare the scratch repair coating. The scratch repairing coating prepared by the invention has good self-repairing performance, flame retardant property, corrosion resistance and mechanical property.

Provided in the present invention are a tetrahydropyridopyrazole derivative and use thereof in medicine. Specifically provided is a compound as shown in general formula (I) or a racemate, stereoisomer, tautomer, deuterated substance, solvate, prodrug, metabolite, pharmaceutically acceptable salt or eutectic crystal thereof, an intermediate thereof, a preparation method therefor, and use thereof in the preparation of a related drug for treating diabetes or obesity.

The invention relates to the technical field of lithium-sulfur batteries, and discloses a sulfonyl ZIF-8 metal organic framework material, a lithium-sulfur battery diaphragm and a preparation method of the lithium-sulfur battery diaphragm. The preparation method of the sulfonyl ZIF-8 metal organic framework material comprises the following steps: dissolving a metal precursor and a mixed ligand in an organic solvent, and carrying out a coordination reaction under the action of organic alkali; solid is collected, washed and dried, and the sulfonic group ZIF-8 metal organic framework material is obtained. The metal precursor is soluble zinc salt; the mixed ligand comprises 2-methylimidazole and an imidazole derivative containing a sulfonic acid group. The sulfo group ZIF-8 metal organic framework material is prepared through a ligand doping strategy and is used for functional modification of the lithium-sulfur battery diaphragm; the shuttle behavior of lithium polysulfide (LiPS) can be effectively inhibited through the electrostatic repulsion effect of sulfonic acid groups and the synergistic effect of high-polarity adsorption sites; and the migration of Li < + > and the conversion efficiency of LiPS are remarkably promoted by an efficient ion transmission network, so that the cycle performance of the lithium-sulfur battery is improved.

The invention discloses a polyimidazolone compound as well as a preparation method and application thereof. The preparation method comprises the following steps: dissolving a bilateral alkyne ester compound, amidine hydrochloride, a catalyst and a desalting agent in an organic solvent, and carrying out polymerization reaction to obtain the polyimidazolone compound. The polyimidazolone compound with the five-membered ring is selectively generated, and the method has the advantages that monomers are easy to obtain, operation is easy, and by-products are low in toxicity. The polyimidazolone compound prepared by the invention has better machinability and has potential application value in the aspects of metal ion detection and biogenic amine detection.

The invention discloses a flame-retardant corrosion-resistant coating and a preparation method thereof, and relates to the technical field of coatings. When the flame-retardant and corrosion-resistant coating is prepared, hexaaryl biimidazole and epoxy chloropropane are subjected to a reaction, and epoxidized hexaaryl biimidazole is prepared; the pre-modified mica sheet and 3-aminopropyltriethoxysilane are subjected to a reaction, and a modified mica sheet is prepared; the preparation method comprises the following steps: reacting allyl amine with 4 '-[4-(bromomethyl) phenyl]-2, 2': 6 ', 2' '-terpyridyl to obtain allyl terpyridyl; the preparation method comprises the following steps: reacting epoxy resin with allyl terpyridyl to obtain modified epoxy resin; and uniformly mixing the modified epoxy resin, epoxidized hexaaryl biimidazole, the modified mica sheet, isophorone diamine and acetone to prepare the flame-retardant corrosion-resistant coating. The flame-retardant corrosion-resistant coating prepared by the invention has excellent corrosion resistance, flame retardance and self-repairing performance.

The application relates to a compound of formula (I) containing a thiazole ring, an indazol ring and a 6,7-dihydro-5H-pyrrolo[1,2-c]imidazole ring system, to pharmaceutical compositions containing it and its medical use. The compounds are described as selective allosteric inhibitors of T790M / L858R, T790M / L858R / C797S, L858R, L858R / C797S containing EGFR mutants and thus useful for the treatment of cancer, in particular non-small cell lung cancer.

The invention belongs to the technical field of sewage treatment, and particularly relates to a demulsifier for eliminating an oil-water interface emulsion layer in oilfield produced liquid treatment and a preparation method of the demulsifier. The preparation method comprises the following steps: adding acrylamide, 1-allyl-3-methylimidazolium bis (trifluoromethanesulfonyl) imine salt, allyl tributyl phosphonium chloride and deionized water into a first reactor, and heating and dissolving the acrylamide, the 1-allyl-3-methylimidazolium bis (trifluoromethanesulfonyl) imine salt, the allyl tributyl phosphonium chloride and the deionized water; adding allyl (diisopropylamino) dimethylsilane, butyl acrylate, deionized water, octylphenol polyoxyethylene ether-10, lauryl sodium sulfate and monopotassium phosphate into the second reactor, and stirring to obtain an emulsion; adding an initiator and sodium hydrogen sulfite into a second reactor, carrying out heating and heat preservation reaction, pouring the mixed solution in the first reactor, and continuously carrying out reaction, heating and heat preservation to obtain a viscous liquid; and drying and granulating the viscous liquid to obtain the demulsifier. The demulsifier provided by the invention has the characteristics of simple synthesis process and high demulsification rate.

The present application relates to a kind of dihydrocarbylimidazole biomimetic lipid compound and its preparation method and application, dihydrocarbylimidazole biomimetic lipid compound structure imitates natural phospholipid design, modification is not less than 10 carbon atoms alkyl on the 4th and 5th of imidazole, and modification is different alkyl chain length primary amine on 2nd position;Dihydrocarbylimidazole biomimetic lipid compound is mixed with therapeutic drug and other adjuvant, can be prepared to be loaded in the lipid nanoparticle of therapeutic drug, can be used as drug delivery system for the preparation of brain-targeted drug.Dihydrocarbylimidazole biomimetic lipid has the function of dynamic control blood-brain barrier, can realize the reversible opening of blood-brain barrier;Formed drug-loaded lipid composition can cross blood-brain barrier and better realize the brain-targeted delivery of loaded therapeutic drug;Drug-loaded lipid composition consisting of dihydrocarbylimidazole biomimetic lipid belongs to a new generation of biomimetic nanomedicine carrier, provides new strategy for realizing the brain-targeted delivery of different kinds of drugs.

The invention provides a composite reagent system and a chalcopyrite and sphalerite collecting method, and belongs to the technical field of mineral processing. The composite reagent system comprises a histidine derived functional group collecting agent and a black agent, and the histidine derived functional group collecting agent (containing a total sulfur ester group, a sulfydryl functional group and a side chain imidazole ring) serves as a core and is compounded with the black agent according to a specific proportion to form a target combination-synergistic interaction flotation mechanism. The histidine derivative collecting agent derives high-activity functional groups under the alkaline condition, and after sulfydryl is dissociated, stable chemical bonds are formed by the dissociated sulfydryl and metal ions on the surfaces of the chalcopyrite and the zinc sulfide. The black powder serves as an auxiliary collecting agent, and the collecting capacity of fine-grain or low-activity sulfide minerals is enhanced through chemical adsorption of dithiophosphate radicals and metal ions on the surfaces of the chalcopyrite and the sphalerite. After the two components are compounded, the selective enrichment efficiency of copper-zinc minerals in the flotation process is remarkably improved.

The invention provides a zeolite imidazate framework fluorescent material and a preparation method and application thereof, and belongs to the technical field of detection material preparation and environment. Quantum dots, a molecular imprinting technology and an MOFs material are combined, firstly, Mg and N co-doped graphene quantum dots and ZIF-8 are compounded, then imprinting is carried out on the surface of ZIF-8, and the zeolite imidazate framework fluorescent material based on MOFs is obtained. In the zeolite imidazate framework fluorescent material, Mg and N co-doped graphene quantum dots not only have good fluorescence performance, but also can generate electron transfer with SDZ to form hydrogen-bond-like acting force, imprinted holes similar to a target object in size and shape are reserved in the surface of the imprinted material, and the target object needing to be detected can be selectively recognized; the zeolite imidazate framework fluorescent material can be used for detecting sulfadiazine in the environment and has good practicability.

The invention provides a flexible HP-ZIF-67 (at) Au surface enhanced Raman scattering substrate for multi-phase detection of volatile organic gas and pesticide residues, and a preparation method and application thereof, and belongs to the technical field of volatile organic gas and pesticide residue detection. The preparation method comprises the following steps: preparing a polystyrene microsphere template by taking polyvinylpyrrolidone, styrene and potassium persulfate as raw materials, then adding 2-methylimidazole and cobalt nitrate to obtain HP-ZIF-67 particles, dispersing the HP-ZIF-67 particles on an aluminum foil to obtain an HP-ZIF-67 substrate, and continuing to diffuse and deposit a gold nanoparticle layer to obtain the flexible HP-ZIF-67 (at) Au surface enhanced Raman scattering substrate. The flexible HP-ZIF-67 (at) Au surface enhanced Raman scattering substrate provided by the invention has the advantages of stable process, high sensitivity and multiphase detection, and a novel composite material is provided for volatile organic gas and pesticide residue detection.

The invention discloses a preparation method of a photocatalytic nanofiltration membrane based on IL-GQDs. The method comprises the following steps: pretreating bagasse, and applying the pretreated bagasse and imidazole ionic liquid (IL) to preparation of ionic liquid functionalized graphene quantum dots (IL-GQDs); the IL-GQDs are uniformly distributed on the surface of the base membrane by utilizing a vacuum-assisted low-temperature interfacial polymerization technology to form an ultrathin photocatalytic active layer; and finally, curing and cleaning to obtain the photocatalytic nanofiltration membrane based on the IL-GQDs. According to the prepared IL-GQDs, the membrane surface is endowed with high specific surface area and excellent photocatalytic activity, and meanwhile, an additional water transmission channel can be established under the condition that the pore diameter of the membrane is not changed, so that the problem of trade-off of a traditional membrane is solved. In addition, through combination of low-temperature and vacuum-assisted interfacial polymerization technologies, the membrane structure is more uniform and compact, defects on the surface of the membrane are reduced, and the stability and the anti-pollution capacity of the membrane are improved. The membrane disclosed by the invention shows relatively high water flux, salt recovery rate and long-term stability in water treatment application.

The invention relates to the technical field of proton exchange membrane fuel cell cathode catalysts, and discloses a nanoscale high-entropy intermetallic compound catalyst and a preparation method and application thereof. According to the nanoscale high-entropy intermetallic compound catalyst, a nitrogen-doped porous carbon material derived from zeolite imidazole skeleton-8 is taken as a carrier, and the metal elements of a high-entropy intermetallic compound comprise platinum, copper, cobalt, nickel and iron or platinum, ruthenium, copper, cobalt, nickel and iron. The preparation method of the catalyst comprises the following steps: step 1, preparing a zeolite imidazole framework 8; 2, preparing and purifying a nitrogen-doped porous carbon material carrier; step 3, loading a metal precursor; and 4, preparing the nano-scale high-entropy intermetallic compound catalyst. Nanoscale, high dispersity and structure ordering of the high-entropy intermetallic compound are achieved, the high-entropy intermetallic compound serves as a PEMFC cathode catalyst, the ORR quality activity and durability can be remarkably improved, and Pt loading capacity and cost are effectively reduced.

The invention relates to injectable hydrogel for rapid hemostasis and antibiosis of an oral cavity as well as a preparation method and application of the injectable hydrogel, and the injectable hydrogel comprises the following components in percentage by weight: 5-15% of aminated chondroitin sulfate, 5-15% of oxidized dextran, 1-3% of platelet-rich fibrin and 0.5-1% of quercetin modified zeolite imidazole acid framework nanoparticles. According to the invention, Chs-ADH and ODex are adopted as matrix materials, PRF and ZIF-8 (at) QCT are introduced, the hydrogel is endowed with antibacterial, anti-oxidation and immunoregulation functions, and by optimizing the proportion of the components, the obtained hydrogel has good injectability, stability and degradation resistance, so that the hydrogel can still maintain an effective blood coagulation function in a high-humidity and high-enzymatic-activity oral environment.

The invention discloses unsaturated polyester resin for an unmanned aerial vehicle fuselage and a preparation method of the unsaturated polyester resin, and relates to the field of high polymer materials. When the unsaturated polyester resin for the unmanned aerial vehicle fuselage is prepared, a flame-retardant monomer reacts with 2-hydroxy-5-(hydroxymethyl) benzaldehyde to prepare a modified flame-retardant monomer; reacting cellulose with acrylic acid to obtain pre-modified cellulose; the pre-modified cellulose, 1-allyl-1, 1, 3, 3-tetramethyldisiloxane and chloroplatinic acid are subjected to a reaction, and modified cellulose is prepared; maleic anhydride, 5-(1H-imidazole-1-yl)-1, 3-phthalic acid, propylene glycol and the modified flame-retardant monomer are subjected to a reaction, and pre-polyester is prepared; and stirring the pre-polyester, zinc chloride, modified cellulose, benzophenone peroxide and styrene to obtain the anti-aging coating. The prepared unsaturated polyester resin for the unmanned aerial vehicle fuselage has good anti-aging, self-repairing, flame-retardant and self-cleaning performance.

The invention provides a thermal interface material based on vinyl imidazole ionic liquid as well as a preparation method and application of the thermal interface material. The thermal interface material is prepared from the following raw materials: the vinyl imidazole ionic liquid, a heat-conducting filler subjected to surface treatment by a silane coupling agent, an initiator and a cross-linking agent. The thermal interface material is based on the vinyl imidazole ionic liquid and the heat-conducting filler, the limitation of a traditional thermal interface material base body is broken through, dispensing can be achieved, no solvent is needed in the preparation process, the adverse effect of solvent residues on the performance of a chip when the thermal interface material is applied to the chip subsequently can be avoided, and the thermal interface material has ideal interface bonding strength; the heat conduction effect is remarkable and stable, the heat stability is good, the material can be well attached to an interface, the problems of stress concentration, cracks and the like are not prone to occurring, and the material can be widely applied to the heat conduction and heat dissipation fields of aerospace, advanced energy, electronic information, military industry and the like.

The invention belongs to the technical field of fuel cell non-noble metal catalyst material preparation, and particularly relates to a composite carbon nanofiber catalyst as well as a preparation method and application thereof. The preparation method comprises the following steps: firstly, combining metal ions with an organic ligand in an organic solvent at room temperature to successfully prepare a zeolite imidazate framework material (ZIFs); the preparation method comprises the following steps: carrying out primary carbonization on a prepared ZIFs material in an inert atmosphere high-temperature furnace to obtain a metal nitrogen carbon material, then uniformly mixing the metal nitrogen carbon material with a spinning solution, carrying out electrostatic spinning to obtain composite nanofibers, and then carrying out secondary carbonization in an inert atmosphere to finally successfully prepare the composite carbon nanofiber catalyst (MN-CNF). The catalyst has excellent electrocatalytic activity, can effectively improve the efficiency of oxygen reduction reaction (ORR) and oxygen evolution reaction (OER), and also has excellent catalytic stability.

The invention discloses an energy-saving and environment-friendly polyarylate fabric whole-core flame-retardant conveying belt and a manufacturing method thereof. The energy-saving and environment-friendly polyarylate fabric whole-core flame-retardant conveying belt comprises a polyarylate fabric whole belt core, a covering layer and a belt core dipping sizing material, the covering layer comprises the following components: solution polymerized styrene-butadiene rubber, a styrene-butadiene-styrene block copolymer, a thermoplastic polyurethane elastomer, zinc oxide, stearic acid, sulfur, an accelerant, an anti-aging agent, carbon black, a hybrid flame-retardant composite material, a phosphate flame retardant, paraffin oil and an antistatic agent; the covering layer of the energy-saving and environment-friendly polyarylate fabric whole-core flame-retardant conveying belt prepared by the invention is compounded from white carbon black, expanded graphite, diethyl aluminum hypophosphite and dimethyl imidazole zinc, and is subjected to surface treatment through polyacrylamide; and then the styrene-butadiene-styrene block copolymer is used for carrying out macromolecular modification on the hybrid flame-retardant composite material, so that the prepared conveyor belt has excellent flame-retardant and antistatic properties, environment-friendly properties, low rolling resistance and mechanical properties.

The invention relates to the technical field of analysis and detection, in particular to a molecularly imprinted sensor for in-situ detection of epicatechin in plant leaves and a preparation and application method of the molecularly imprinted sensor. The molecular imprinting sensor for detecting epicatechin is prepared by assembling a zeolite imidazate skeleton-amide functionalized single-walled carbon nanotube composite material, amino-formyl imidazole modified reduced graphene and an MIP film on the surface of an electrode layer by layer. The high-selectivity and high-sensitivity detection on the target molecule epicatechin is realized. The technology can effectively reduce the detection cost, simplify the operation process and improve the performance of the sensor. Particularly, due to the introduction of the MIP, the sensor has the capabilities of in-situ detection and high-precision molecular recognition, can realize rapid and reliable quantitative analysis in a complex sample, and has a wide application prospect.

The invention discloses a high-cohesiveness polyimide composite film capable of being used for a flexible copper-clad plate and a preparation method of the high-cohesiveness polyimide composite film. The polyimide composite film is composed of a thermosetting polyimide supporting layer and a thermoplastic polyimide bonding layer arranged on at least one face of the thermosetting polyimide supporting layer. An interface layer formed by reacting amino-terminated hyperbranched polyamide grafted silicon dioxide particles with thermosetting polyamide acid is embedded between the thermosetting polyimide supporting layer and the thermoplastic polyimide bonding layer, and an end group of thermoplastic polyimide contains an imidazole ring capable of forming a complex with copper. The amino-terminated hyperbranched polyamide grafted silicon dioxide particles are embedded into the interface of the thermosetting layer and the thermoplastic layer, so that the contact area of the supporting layer and the adhesive layer is increased; the polyimide composite film with high cohesiveness, high dimensional stability, high heat resistance and low glass transition temperature is prepared.

The invention discloses application of 4, 5-dialkyl imidazole cationic lipid in a drug brain delivery carrier, and belongs to the field of drug delivery. The 4-site and the 5-site of imidazole are respectively modified with alkyl with not less than 10 carbon atoms to form the 4, 5-dialkyl imidazole cationic lipid. The 1, 4, 5-dialkyl imidazole cationic lipid is mixed with a therapeutic drug and other lipid auxiliary materials to prepare drug-loaded lipid nanoparticles loaded with the therapeutic drug, and the drug-loaded lipid nanoparticles can be used as a drug delivery system for brain delivery of the therapeutic drug. The 1, 4, 5-dialkyl imidazole cationic lipid has the function of dynamically regulating and controlling opening and closing of a blood brain barrier, and reversible opening of the blood brain barrier can be achieved; the formed drug carrier can pass through a blood brain barrier and well realize brain delivery of loaded therapeutic drugs, and a new strategy is provided for brain delivery of different types of drugs.

The invention discloses a polyion liquid / polyvinylidene fluoride-hexafluoropropylene-based solid electrolyte with a microscopic liquid phase and a preparation method and application thereof, and the preparation method comprises the following steps: adding a lithium salt into N-methyl-2-pyrrolidone, and stirring until the lithium salt is completely dissolved; then adding imidazolyl polyion liquid to prepare a solution A; adding polyvinylidene fluoride-hexafluoropropylene into N-methyl-2-pyrrolidone to prepare a solution, adding the solution into the solution A, continuously stirring until the solution is fully dissolved to obtain a precursor solution of the solid electrolyte, casting the precursor solution onto a polytetrafluoroethylene mold, and carrying out vacuum drying to obtain the solid electrolyte. And the polyvinylidene fluoride-hexafluoropropylene polymer-based solid electrolyte added with the imidazolyl polyion liquid is prepared by adding the imidazolyl polyion liquid into the polyvinylidene fluoride-hexafluoropropylene polymer-based solid electrolyte. The polymer-based solid electrolyte with a microscopic liquid phase is obtained through an electrolyte preparation process which is mild in condition, simple to operate and easy for large-scale production, and the solid electrolyte has good conductivity and mechanical properties.

The invention discloses preparation and application of an imido covalent organic framework material containing imidazolyl ionic liquid. The imido covalent organic framework material (ILs-TPN-COFs) containing the imidazolyl ionic liquid is obtained by connecting the imidazolyl ionic liquid [CnCmILs (at) Br] to an imido covalent organic framework TPN-COFs through a covalent bond. The material has an ionic liquid tertiary amine N active site and a halogen anion active site, and can promote CO2 activation and ring opening of epoxide. The ILs-TPN-COFs catalytic material has the advantages of uniform distribution of active sites, better stability, easiness in separation of the catalyst from a reaction system, better repeatability and the like. According to the invention, the prepared novel ILs-TPN-COFs material is applied to catalysis of synthesis of propylene carbonate from carbon dioxide and epoxypropane, and shows excellent catalytic performance under mild reaction conditions.

The invention relates to a synthetic method of an ionic liquid and ZIF-8 composite material, which comprises the following steps: S11, adding 2-methylimidazole and octadecyl guanidine chloride into a polyethylene glycol 400 aqueous solution to obtain a solution I; s12, Zn (NO3) 2.6 H2O is added into a polyethylene glycol 400 aqueous solution, and a solution II is obtained; s13, mixing and stirring the solution I and the solution II for reaction, and centrifugally collecting obtained ZIF-8 nanoparticles; s2, adding the ZIF-8 nanoparticles into a sodium phosphotungstate solution, stirring to disperse the ZIF-8 nanoparticles into a suspension, then adding a dodecyl guanidine chloride aqueous solution into the suspension, and carrying out an ion exchange reaction; and centrifuging after the ion exchange reaction is finished. The invention further relates to application of the synthetic method of the ionic liquid and ZIF-8 composite material, and the ionic liquid and ZIF-8 composite material is used for adsorbing 2, 4-D in water. The preparation method is simple, the ionic liquid and the ZIF-8 composite material have good adsorption performance on 2, 4-D in water, and the 2, 4-D is convenient to desorb and is convenient to recycle.

The invention belongs to the technical field of preparation of blocking removers, and particularly relates to a composite chelating blocking remover for an oil field and a preparation method of the composite chelating blocking remover. The composite chelating blocking remover for the oil field is prepared from the following raw materials in percentage by mass: 7 to 9 percent of 1-butyl-3-methylimidazole dodecyl sulfonate, 5 to 7 percent of erucamide propyl hydroxypropyl sulfobetaine, 3 to 4 percent of di-(2-ethylhexyl) sodium sulfosuccinate, 4 to 5 percent of ethylenediamine di-o-hydroxyphenylacetic acid, 5 to 7 percent of N, N '-di (2-hydroxybenzyl) ethylenediamine-N, N'-bis (2-hydroxybenzyl)-N, N '-bis (2-ethylhexyl)-N, N'-bis (2-hydroxybenzyl)-N, N '-bis (2-hydroxybenzyl)-N, N'-bis (2-hydroxyphenyl)-N, N '-bis (2-hydroxyphenyl)-N, N'-bis (2-hydroxyphenyl)-N The cleaning agent is prepared from the following components in percentage by weight: 3 to 4 percent of N, N '-diacetic acid, 2 to 3 percent of O-(3-(benzyloxy) propyl) hydroxylamine, 1 to 2 percent of heptadecenyl hydroxyethyl imidazoline quaternary ammonium salt, 1 to 1.5 percent of dimethyl diallyl ammonium chloride homopolymer and the balance of water. The composite chelating blocking remover for the oil field has excellent scale dissolution rate and paraffin inhibition rate when being applied to complex scale blocking removal of the oil field.