3732results about How to "Prevent proliferation" patented technology

The invention relates to the field of medicinal chemistry, in particular to thiazolidinedione compounds containing quinoline structures and application of the thiazolidinedione compounds. The compound can influence the interaction between KRAS and downstream protein cRaf, namely indirectly inhibits the function of KRAS, and further inhibits the proliferation of tumor cells, and the compound and the pharmaceutical preparation thereof can be used for treating a series of diseases caused by KRAS dysfunction, mainly KRASG12D related cancers, such as KRASG12D related cancers, KRASG12D related cancers, KRASG12D related cancers, KRASG12D related cancers, KRASG12D related cancers, KRASG12D related cancers, for example, colon cancer, rectal cancer, pancreatic cancer, lung cancer, endometrial cancer, skin cancer and the like.

The invention provides application of an SRC inhibitor combined with a KRAS-G12C inhibitor to preparation of a medicine for treating KRAS-G12C mutant lung cancer and a medicine composition, and relates to the technical field of biological medicine, compared with independent use of the KRAS-G12C inhibitor, the scheme of the SRC inhibitor combined with the KRAS-G12C inhibitor can effectively inhibit proliferation and survival of KRAS-G12C mutant lung cancer cells, and the application of the SRC inhibitor combined with the KRAS-G12C inhibitor to preparation of the medicine for treating the KRAS-G12C mutant lung cancer can be used for preparing the medicine for treating the KRAS-G12C mutant lung cancer. The compound can effectively inhibit the activation of a KRAS-MARK pathway and an SRC-FAK pathway, the combination of the compound and the compound has a synergistic anti-tumor effect, and the compound and the compound can be directly combined for medication, can also be prepared into a combined preparation for treating KRAS mutant lung cancer, and have a good clinical transformation prospect.

The invention provides a river section water quality prediction method based on a combined machine learning model, and the method comprises the steps: building river monitoring section long-time sequence water quality big data, standardizing and supplementing water quality index data, preparing a water quality index data set and a water quality evaluation data set, and selecting and processing water quality big data features. Developing a water quality prediction model based on a combined machine learning algorithm, evaluating the performance of the water quality prediction model, and testing the generalization ability of the water quality prediction model. The correlation of river section historical data in a time sequence is fully utilized, the model not only improves the accuracy and real-time performance of water quality prediction, but also enhances the response capability to sudden water quality events, the monitoring and early warning cost is remarkably reduced, the efficiency and scientificity of water environment management are improved, and the method is suitable for popularization and application. The self-learning capability and the high-frequency data processing capability of the system ensure timely updating and long-term effectiveness of a prediction result, and provide solid technical support for water pollution prevention and control and water quality management.

The invention discloses a water quality comprehensive regulation and control intelligent model based on water quality hydrodynamic force, and relates to the technical field of water quality comprehensive regulation and control, which comprises the following steps: constructing a comprehensive meteorological monitoring network, capturing key meteorological parameters of air temperature, rainfall, humidity and wind speed in real time, and formulating water area monitoring paths of an unmanned aerial vehicle and an unmanned ship according to detected environment data; the method comprises the following steps: setting an unmanned aerial vehicle monitoring team to monitor the water surface condition in real time, setting an unmanned ship formation to run according to a formulated route, carrying out key monitoring and sampling on a specific polluted area, constructing a water quality standard-reaching early warning system, and carrying out prediction and early warning simulation calculation and correction, and analyzing and evaluating the water quality condition. According to the water quality comprehensive regulation and control intelligent model based on the water quality hydrodynamic force, water area pollution can be quickly found, pollutants can be traced and researched in time, pollution expansion is prevented, meanwhile, pollution early warning can be conducted according to data, potential environmental risks can be found, and powerful technical support is provided for environmental protection work.

The invention discloses a crop disease remote sensing monitoring and early warning system based on time sequence spectral information analysis, and relates to the technical field of agricultural disease and insect pest monitoring. Computer drawing software is utilized to divide a corn planting field in equal proportion, and sensors are deployed to monitor the growth environment change in each grid in real time and generate microenvironment data information; the method comprises the following steps: calculating a microenvironment difference index Xbd according to microenvironment data, identifying a microenvironment difference aggregation area and sending a risk analysis instruction, after receiving the risk analysis instruction, capturing related spectral data information of the microenvironment difference aggregation area by using an unmanned aerial vehicle and a multispectral sensor, and constructing a multispectral fluctuation coefficient Xgp by analyzing related spectral data, and comparing the calculated rust disease risk assessment index Zpg with a preset threshold W in combination with the microenvironment difference index Xbd and the trained risk assessment model, and obtaining corresponding grade early warning according to the rust disease risk degree.

The invention relates to the technical field of subsynchronous oscillation suppression, in particular to a system for suppressing subsynchronous oscillation of a doubly-fed grid-connected system, and the system comprises a doubly-fed generator module which is used for converting wind power into electric energy; the subsynchronous oscillation spectrum disturbance module specifically comprises a current disturbance generation unit and a phase decoupling optimization unit; and the multi-frequency domain decomposition and absorption module specifically comprises a frequency spectrum decomposition unit and a self-adaptive absorption unit. According to the invention, the current disturbance generation unit actively injects a low-power and non-linearly distributed current disturbance signal, dynamically destroys the coherence of the subsynchronous oscillation signal, and combines the spectrum decomposition unit to accurately identify the subsynchronous oscillation dominant frequency and the harmonic component thereof, thereby refining the distribution analysis of the oscillation energy, and improving the accuracy of the subsynchronous oscillation. The high-precision target positioning capability is provided for the oscillation suppression strategy, the multi-level oscillation suppression from active disturbance to precise control is realized through the cooperative operation of the two, and the stability and adaptability of the system under the complex power grid condition are effectively improved.

The invention discloses a precise advertisement putting optimization method and system, and relates to the technical field of advertisement putting, and the method comprises the following steps: collecting and recording key parameter information of different data sources in a merging process in real time, providing basic data for the subsequent anomaly detection, and providing an optimization result for guaranteeing the comprehensiveness of the data; recording each step of operation in all merging processes; and carrying out anomaly analysis on the key parameter information subjected to the standardized processing, and identifying abnormal data generated in the merging process by analyzing multi-dimensional information. According to the invention, by monitoring the cross-session persistence information and the platform situation consistency information in real time, the system can effectively prevent the problem of data merging errors or segmentation, improve the accuracy of user portraits, and accurately push advertisement contents, thereby improving the click rate and the conversion rate. A multi-level anomaly detection and grading processing mechanism ensures that risks are timely handled, the safety of data integration and the stability of advertisement putting are improved, and the data integrity is guaranteed.

The invention relates to the technical field of microorganisms, in particular to a viable bacterium preparation of a lactobacillus paracasei strain as well as a preparation method and application of the viable bacterium preparation. The viable bacterium preparation comprises a lactobacillus paracasei strain and auxiliary materials, and the preservation number of the lactobacillus paracasei strain is CGMCC (China General Microbiological Culture Collection Center) No.27974. The viable bacterium preparation can inhibit the growth of streptococcus mutans, reduce the formation of a dental plaque biofilm caused by the streptococcus mutans, reduce the content of a mature dental plaque biofilm, inhibit the level of water-insoluble exopolysaccharides generated by the streptococcus mutans, reduce the expression quantity of cariogenic genes gtfB, gtfC, gtfD, ftf and LuxS of the streptococcus mutans, improve the cariogenic activity of the streptococcus mutans and improve the cariogenic activity of the streptococcus mutans. The adhesion rate of streptococcus mutans on a hydroxyapatite tooth model is reduced, and a beneficial in-vitro probiotic function is achieved.

The invention discloses carboxymethyl chitosan-hyaluronic acid-stem cell exosome eye drops as well as a preparation method and application thereof, and relates to the technical field of eye drops and medical biogel. The carboxymethyl chitosan-hyaluronic acid-stem cell exosome eye drops are prepared from tannic acid modified carboxymethyl chitosan and adipose tissue-derived stromal cell exosome freeze-dried powder, the carboxymethyl chitosan-hyaluronic acid-stem cell exosome eye drops provided by the invention can effectively treat xerophthalmia, and are stable in components, safe and reliable. The three components including the tannic acid modified carboxymethyl chitosan, the hyaluronic acid and the adipose tissue-derived stromal cell exosome coexist, so that the functions of all the components can be fully played, a synergistic effect is achieved, and a better treatment effect on xerophthalmia is achieved.

The invention relates to a battery module capable of effectively preventing thermal runaway diffusion, a protection method of the battery module and an energy storage device. The battery module comprises an upper shell, a lower box body, a battery module, a pressure relief flow guide part, a panel structural part and a CCS assembly, the upper shell and the lower box body form a containing cavity; at least one group of battery modules are arranged in the accommodating cavity; the battery module comprises at least one battery monomer, the battery monomers are connected in series, a safety valve is arranged on each battery monomer, and a pressure relief flow guide part is arranged above the safety valve; a panel structural member is arranged at one end of the battery module along the arrangement direction of the battery monomers; and a CCS assembly is arranged above the battery module. According to the invention, gas and electrolyte can be separated after the single battery is sprayed, and are respectively and directionally discharged, so that the situation that other normal single batteries or modules are damaged due to disordered splashing of sprayed objects is avoided, and spontaneous combustion or explosion of the battery module is avoided.

The invention discloses an air conditioner control method and device, an air conditioner, a storage medium and a computer program product. A humidifying part is arranged in an indoor unit of the air conditioner. The method comprises the steps that in the refrigeration operation process of the air conditioner, an initial temperature point used for starting peculiar smell removal of the indoor unit is determined according to the set temperature; according to the indoor environment temperature and the starting temperature point, whether the indoor unit starts peculiar smell removal or not is determined; and if it is determined that the peculiar smell of the indoor unit begins to be removed, a humidifying component is started, and the humidifying speed of the humidifying component, the air gear of an inner draught fan and the operation frequency of a compressor are controlled according to the indoor environment temperature and the set temperature. According to the scheme, the thicker water film is always kept on the surface of the indoor heat exchanger in the refrigeration process of the air conditioner, and peculiar smell is prevented from being diffused into a room due to evaporation of the water film, so that discomfort of a user is avoided, the comfort of the indoor environment is improved, and the user experience is improved.

The invention discloses a PROTACs compound for targeted degradation of PRMT5 and application of the PROTACs compound. The PROTACs compound comprises a compound as shown in the following formula, and related analogues or pharmaceutically acceptable salts, metabolites or prodrugs of the compound: in the # imgabs0 # formula, X represents a ligand bound to PRMT5 protein, Z represents a ligand of E3 ubiquitin ligase, and Y represents a linking group for linking X and Z; according to the invention, CRBN is used as E3 ligase, and a series of PRMT5-targeted PROTAC degradation compounds are designed and synthesized. The compound can effectively induce PRMT5 degradation, significantly inhibit proliferation, growth, migration, infiltration, clone formation and metastasis of tumor cells, promote apoptosis of cancer cells, promote autophagy of the tumor cells, prevent or overcome drug resistance of BTK inhibitors and / or prolong the lifetime of tumor patients, and has wide application prospects.

The invention discloses a high-strength cold-resistant fiber and a preparation method thereof, and relates to the field of fibers. When the high-strength cold-resistant fiber is prepared, diphenylphosphine sequentially reacts with triallylmethoxysilane and nickel bromide, and a silicon-phosphorus-nickel complex is prepared; the preparation method comprises the following steps: reacting an alkene mixed solution, azodiisobutyronitrile, a hydrochloric acid solution and a silicon mixed solution, diluting with 4-methyl cyclohexanone, and reacting with zinc bromide to prepare a pre-modified polyacrylate emulsion; the preparation method comprises the following steps: carrying out a batch reaction on graphene oxide and 1-aminopyrrole to prepare modified graphene oxide; the modified graphene oxide, 2, 5-dihydroxy terephthalaldehyde and the pre-modified polyacrylate emulsion react and then electrostatic spinning is conducted, and the high-strength cold-resistant fiber is prepared. The high-strength cold-resistant fiber prepared by the invention has antibacterial, anti-aging, flame-retardant and antistatic capabilities.

The invention relates to the technical field of bearing detection, in particular to bearing detection equipment for bearing production and processing. The speed measurement sensor is arranged on the top surface of one side of the test bench, is matched with the layout of the ball cylinder and is used for monitoring the rotating speed of the inner ring and the outer ring of the bearing; the clamping parts are arranged on the two sides of the partition of the test board respectively and used for fixing the positions of inner and outer rings of the bearing; and the switching parts are symmetrically arranged in the test board and are matched with the rotation of the turntable and are quickly switched so as to push the inner ring or the outer ring of the bearing to rotate for rotating speed test. Through the clamping part and the switching part which are operated together, the movement of the inner clamping plate and the outer clamping plate is controlled by utilizing different rotating directions of the turntable, so that the bearing is accurately clamped and fixed at different ring positions according to the detection condition, and then the turntable rotates to synchronously push the air pipe to change the position, so that the inner and outer ring detection of the bearing can be independently operated; therefore, more comprehensive bearing detection is achieved, and double improvement of simple and convenient operation and detection precision is realized.

The invention discloses a traceability tracking method and system for cosmetic electronic two-dimensional codes, and relates to the technical field of cosmetic traceability tracking. According to the traceability tracking method of the cosmetic electronic two-dimensional code, after a production link is finished, data such as production original ingredient quality, component stability and production environment are stored in the two-dimensional code, scanning traceability analysis is carried out in the next link, production quality related indexes are calculated, whether the product is qualified or not is comprehensively judged, qualified products continue to be produced, and unqualified products are screened and processed. According to the invention, after each production link is finished, the production data including the original ingredient quality, the component stability, the production environment and other information are dynamically stored, a complete link recording chain is formed, the data are updated in real time through the electronic two-dimensional code, the synchronization of the traceability information and the actual production is ensured, the real-time performance and the traceability efficiency of the data are improved, and the production efficiency is improved. According to the link-by-link tracking mechanism, the transparency of the cosmetic production process is remarkably improved, so that the specific production link can be quickly positioned when the quality problem occurs.

The invention discloses a radial flow field bipolar plate and a fuel cell stack structure, and belongs to the technical field of fuel cells, the radial flow field bipolar plate comprises a bipolar plate body, two sides of the bipolar plate body are respectively provided with an anode side groove and a cathode side groove, the middle part of the bipolar plate body is provided with a cathode air inlet channel, and one side of the cathode air inlet channel is connected with a connecting cylinder; a plurality of anode rib plates which are distributed in a multi-stage arc shape are arranged on the bottom surface of the anode side groove, and two anode air holes are formed in the side wall of the anode side groove; a plurality of cathode rib columns distributed in a multistage radial mode are arranged on the bottom face of the cathode side groove, cathode air inlet holes are formed in the side wall of the connecting cylinder, and cathode air outlet holes are formed in the side wall of the cathode side groove in a penetrating mode. The structure is simple and compact, stacking is convenient, the gas flowing state is effectively improved, more uniform gas distribution is realized, uniform reaction in the whole electric pile is ensured, and the efficiency and performance of the electric pile are improved; and the pressure drop during gas flowing can be reduced, so that the operation of the galvanic pile is more energy-saving and efficient.

The invention relates to the technical field of preparation of antibacterial gloves, in particular to a preparation method of degradable breathable antibacterial gloves, and an emulsion formula of the degradable breathable antibacterial gloves comprises the following components in parts by weight: 100 parts of nitrile rubber modified polylactic acid, 5-10 parts of modified antibacterial filler, 1-3 parts of an anti-aging agent, 0.5-3 parts of a vulcanizing agent, 0.3-2 parts of a vulcanization accelerator and 0.5-1 part of a foaming agent. Through a high-molecular compound composition system, nitrile rubber modified polylactic acid, modified antibacterial filler and other components are compounded to prepare the glove with controllable degradability, lasting antibacterial property and good air permeability; on the basis of covalent binding of silicon dioxide loaded with antibacterial groups and modified chitosan, the synergistic antibacterial effect of the modified antibacterial filler is achieved, and therefore the antibacterial performance of the glove is improved.

The invention relates to the technical field of infectious disease prevention and control, in particular to an infectious disease epidemic situation space-time aggregation analysis method and system, and the method comprises the steps: constructing a case growth trajectory propagation model and an epidemic situation propagation and diffusion model through a data warehouse; predicting an epidemic situation diffusion path and a time-space coverage change graph by using the case growth trajectory propagation model and the epidemic situation propagation and diffusion model; and fusing the predicted epidemic situation diffusion path and the time-space coverage change map with the spatial data of the key public place, and calculating to obtain an epidemic situation influence index of the key public place. By constructing the case growth trajectory propagation model and the epidemic situation propagation and diffusion model, the diffusion path and the space-time coverage change of the epidemic situation can be predicted more accurately, a more scientific basis is provided for prevention and control work, and according to the predicted epidemic situation diffusion condition and the key public occasion epidemic situation influence index, the prediction of the epidemic situation is realized. Medical resources, manpower, materials and the like can be configured more reasonably, and the prevention and control efficiency is improved.

The invention belongs to the technical field of biomedicine, and particularly relates to a nano antibody aiming at influenza A virus H1N1 subtype NA protein and application. The nano antibody comprises an amino acid sequence as shown in SEQ ID NO: 1 or consists of the amino acid sequence as shown in SEQ ID NO: 1. The nano antibody has high affinity, and experimental results show that the antibody can effectively inhibit proliferation of PR8 H1N1 virus in vivo and resist infection of lethal dose virus on mice. Meanwhile, the nano antibody is the first nano antibody which aims at the N1 subtype NA protein and has prevention and treatment effects, the market blank is filled, and the nano antibody can be applied to the fields of laboratory research, biosensor development, clinical diagnosis, infection prevention and treatment and the like. The nano antibody provided by the invention has the advantages of small molecular weight, high stability, low production cost and the like, and has wider application potential and market competitive advantages compared with the traditional IgG antibody.

The invention belongs to the field of tumor treatment medicines, and particularly relates to a stabilizing agent aiming at BRD7 tumor suppressor protein, which is a free compound with a structure # imgabs0 # as shown in a formula 1, pharmaceutically acceptable salt, crystal and solvate. The invention also comprises application of the stabilizing agent of the targeted BRD7 tumor suppressor protein in preparation of drugs for treating solid tumors. Researches show that the compound in the formula 1 has an effect of stabilizing BRD7 protein, and can realize efficient inhibition on solid tumors such as breast cancer, nasopharynx cancer and lung cancer based on a mechanism of stabilizing BRD7 tumor suppressor protein.

The invention discloses an application of isorhamnetin-3-O-neohesperidin in preparation of a medicine for preventing and / or treating benign prostatic hyperplasia. In-vitro experiments show that the isorhamnetin-3-O-neohesperidin can inhibit proliferation of prostatic hyperplasia cells, promote apoptosis of the prostatic hyperplasia cells and regulate inflammatory response of the prostatic hyperplasia cells, and rat experiments show that the isorhamnetin-3-O-neohesperidin can improve the hormone endocrine disorder condition of an animal model body, and can inhibit the prostatic hyperplasia cells and promote the prostatic hyperplasia cell apoptosis and regulate the inflammatory response of the prostatic hyperplasia cells. The anti-inflammatory ability of an animal model is enhanced, and the traditional Chinese medicine composition has a relatively good treatment effect on prostatic hyperplasia caused by testosterone propionate. The medicine for preventing and / or treating benign prostatic hyperplasia, provided by the invention, contains a pharmacodynamic dose of isorhamnetin-3-O-neohesperidin and a pharmaceutically acceptable carrier or auxiliary material, can be prepared into a medicine dosage form which is convenient for clinical use and can play an optimal curative effect, and has a relatively high clinical application value.

The invention discloses a picture mounting metal outer frame laser cutting machine with a dust removal structure, and belongs to the technical field of laser cutting. The picture mounting metal outer frame laser cutting machine comprises a workbench and a portal frame capable of moving in the length direction of the workbench; a plurality of placement blocks are uniformly arranged on the upper surface of the workbench in the length direction, placement grooves are formed in the placement blocks, an air suction purification mechanism is arranged on the portal frame and comprises two air suction pipes, and one ends of the two air suction pipes penetrate through the two sides of the portal frame correspondingly to be connected with air suction hoods; circular dustproof nets are arranged on the sides, close to each other, of the two air suction hoods; during cutting, according to different cutting directions, harmful gas generated by cutting can be effectively adsorbed and purified, metal dust is recycled, pollution to equipment and the environment is reduced, and resource waste is reduced.

The invention relates to low-emissivity coated glass and a preparation method thereof. The low-emissivity coated glass comprises a glass substrate and a coating layer arranged on one side of the glass substrate, the coating layer comprises a base layer, a first seed layer, a first functional layer, a first barrier layer, a second functional layer, a second barrier layer, a second seed layer, a third functional layer, a third barrier layer and a top dielectric layer which are sequentially coated outwards from one side of the glass substrate. According to the invention, the barrier layer is controlled to adopt the metal simple substance with excellent compactness and stability and high melting point or the barrier layer is controlled to adopt the nitride, the silicon nitride, the silicon carbonitride or the silicon boron nitride and the like of the metal material, so that the function layer is protected from being oxidized, the radiation rate and the reflectivity are low, and the service life is long. And stability is achieved in the heat treatment process.

The invention provides a product whole-process supervision method and system based on a block chain, belongs to the field of computers, and solves the problem that the block chain cannot verify the authenticity of input data in a commodity traceability system. The method comprises the following steps: acquiring initial state information after agricultural and sideline products are produced, wherein the initial state information comprises growth data, initial appearance data and initial weight data; obtaining full-process environmental condition parameters of storage, transportation and sales and stage state information of the agricultural and sideline products at each process transfer node, wherein the stage state information comprises stage appearance data and stage weight data; and on the basis of the initial state information or the stage state information and each process environment condition parameter, predicting ideal state information of the agricultural and sideline products at the next process transfer node, so that the agricultural and sideline products can be obtained under the condition that the matching degree of the ideal state information and the recorded stage state information is lower than a preset matching degree. And generating a process environment condition parameter authenticity alarm and recording the process environment condition parameter authenticity alarm to the block chain system.

The invention discloses a water area pollutant emergency treatment system and equipment in the technical field of water pollution treatment, and the system comprises a plurality of water quality monitoring modules which are used for collecting water quality factors of a covered area and generating real-time water quality data; the data collection module is used for acquiring, storing and forwarding real-time water quality data; the prediction module is used for analyzing and predicting the pollutant component evolution condition based on the real-time water quality data by using a big data model, and generating a pollutant component evolution condition graph of the water area; the emergency preprocessing scheme generation module is used for generating a corresponding preprocessing scheme and a preprocessing position based on the pollutant diffusion range diagram and the pollutant component evolution situation diagram; the biological filtration assemblies are used for being deployed at the pretreatment position and filtering and cleaning the water area. Plants aiming at specific pollutants are planted on the biological filtration assembly, and long-term ecological restoration can be achieved while water area pollutants are emergently treated.

The invention discloses a livestock composite biological feed prepared from probiotics and a method thereof, and relates to the technical field of livestock feeds. The compound biological feed for the livestock and poultry is prepared from the following raw materials: lactobacillus plantarum BNCC138404, bacillus coagulans BNCC132591, bacillus velezensis BNCC352076, bifidobacterium bifidum BNCC186493, aspergillus niger BNCC147472, enterococcus faecalis BNCC186075, yarrowia lipolytica BNCC193899, nutrient substances, mineral trace elements, vitamins, amino acids and prebiotics. The compound biological feed for the livestock and poultry is prepared from the following raw materials: lactobacillus plantarum BNCC138404, bacillus coagulans BNCC132591, bacillus velezensis BNCC352076, bifidobacterium bifidum BNCC186493, aspergillus The compound biological feed fermented by adopting various probiotics can improve the antioxidant level of the broiler chicken, improve the health condition of intestinal tracts, increase the villus height and the villus-implicit ratio of the jejunum of the broiler chicken and reduce the occurrence of intestinal inflammation, so that the growth performance of the broiler chicken is promoted, and the immune performance of the body is improved.

The invention discloses a preparation method of an all-solid-state battery negative electrode material, and belongs to the technical field of negative electrode materials, the method comprises the following steps: firstly, weighing a certain mass of red phosphorus and nano silicon, and carrying out ball milling and mixing to obtain a mixture; then carrying out ball-milling mixing on the mixture and cyclodextrin to obtain a phosphorus-silicon composite material; and finally, putting the phosphorus-silicon composite material into a polyacyl chloride solution to react for a period of time, and treating to obtain the all-solid-state battery negative electrode material. According to the invention, the cyclodextrin coated with the phosphorus-silicon mixture reacts with the poly-acyl chloride solution, and the phosphorus-silicon composite material is further encapsulated in the molecular cavity, so that phosphorus and silicon are prevented from diffusing out of the molecular cavity under the action of pressure.

The invention relates to the field of oncology and diagnosis, in particular to a target spot for treating pancreatic cancer and application of the target spot. Experiments discover that the 176-site lysine lactylation modification (HNRNPC K176la) level of the HNRNPC protein is remarkably increased in pancreatic cancer, existence of site modification is confirmed through a pan-lactylation modification antibody for the first time, and meanwhile, the K176 site is confirmed to be a key site for carrying out lactylation modification on the HNRNPC in the pancreatic cancer. Furthermore, in-vivo and in-vitro functional experiments prove that HNRNPC K176 lactic acid modification can inhibit proliferation of pancreatic cancer cells and increase of tumor volume.

The invention discloses an application of an Ms-Piscidin antibacterial peptide in preparation of a largemouth bass rhabdovirus inhibitor or a treatment drug, and is characterized by providing an application of the Ms-Piscidin antibacterial peptide in preparation of the largemouth bass rhabdovirus inhibitor and an application of the Ms-Piscidin antibacterial peptide in preparation of the treatment drug for largemouth bass rhabdovirus infection. The amino acid sequence of the Ms-Piscidin antibacterial peptide is as shown in SEQ ID NO.1: FLKHIKSFWRGAKAIFRGARQGWREHR. The Ms-Piscidin antibacterial peptide has the advantages that the Ms-Piscidin antibacterial peptide can inhibit MSRV proliferation, the survival rate of micropterus salmoides infected by MSRV is increased, and the Ms-Piscidin antibacterial peptide can be used as a potential medicine for preventing and treating MSRV infection diseases.

The invention belongs to the technical field of film recycling, and discloses a waste film recycling device which comprises a base, a supporting box is installed at the top of the base, a box body is fixedly connected to the top of the supporting box, a feeding hole is formed in the side wall of the box body, a conveying frame is installed at the feeding hole, and a supporting plate is fixedly connected to the bottom of the conveying frame. A second belt conveyor is installed on the inner wall of the conveying frame, second sliding holes are formed in the two sides of the conveying frame correspondingly, second sliding blocks are slidably connected to the inner walls of the two second sliding holes correspondingly, the plastic film is conveyed through the second belt conveyor, and the plastic film is dried through a second drying machine; dust is blown into the box body through an air blower, dust diffusion generated during drying is avoided, and therefore clods on the surface of the plastic film can be dried in the plastic film conveying process, the pressure of equipment for later cleaning is reduced, the effect of saving water is achieved, and the cleaning cost is reduced.