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159 results about "Arabinose" patented technology

Arabinose is an aldopentose – a monosaccharide containing five carbon atoms, and including an aldehyde (CHO) functional group. For biosynthetic reasons, most saccharides are almost always more abundant in nature as the "D"-form, or structurally analogous to D-glyceraldehyde. However, L-arabinose is in fact more common than D-arabinose in nature and is found in nature as a component of biopolymers such as hemicellulose and pectin.

An in vitro cell-free protein synthesis system (D2P system), its reagent kit and its applications

This invention provides an in vitro cell-free protein synthesis system, its reagent kit, and its applications, belonging to the field of protein synthesis technology. This invention improves an in vitro cell-free protein synthesis system based on Kluyveromyces lactis by adding exogenous L-arabinose, significantly enhancing the system's protein synthesis capacity. Furthermore, it provides a more efficient and higher-throughput in vitro protein synthesis reagent kit and a method for synthesizing exogenous proteins. The improvements provided by this invention can be achieved without molecular modification, are simple and convenient to operate, and save costs.
Owner:KANGMA (SHANGHAI) BIOTECH LTD

Hawthorn heteropolysaccharide as well as preparation method and application thereof

The invention relates to the field of medicines, foods or health-care products, in particular to big-fruit hawthorn heteropolysaccharide as well as a preparation method and application thereof. The large-fruit hawthorn heteropolysaccharide is prepared from galacturonic acid, glucuronic acid, mannose, xylose, arabinose, glucose, galactose, fucose and rhamnose. The weight-average molecular weight of the big fruit hawthorn heteropolysaccharide is 81.6 kDa to 157.3 kDa. The product has unique structures of complex monosaccharide composition, low molecular weight, appropriate uronic acid content, low esterification degree and the like; compared with CP which is single in structure and high in esterification, the CP is better in oxidation resistance and bile acid binding capacity; compared with hawthorn polysaccharide with low uronic acid content and high molecular weight, the hawthorn polysaccharide has the advantages that the enzyme inhibition activity is obviously enhanced, and the hawthorn polysaccharide has a wide prospect in development of functional food, health care products or medicines for regulating blood sugar / blood fat, resisting oxidation and preventing metabolic syndromes.
Owner:GUANGXI ZHUANG AUTONOMOUS REGION ACAD OF AGRI SCI +1

Application of pitaya peel polysaccharide in preparation of medicine for repairing skin wounds

The invention provides application of pitaya peel polysaccharide in preparation of a medicine for repairing skin wounds. The monosaccharide components of the pitaya peel polysaccharide comprise rhamnose, arabinose, galactose, glucose, xylose, mannose, galacturonic acid and glucuronic acid. Research finds that the dragon fruit peel polysaccharide remarkably accelerates the wound healing process and promotes granulation tissue formation and collagen deposition. Meanwhile, the pitaya peel polysaccharide can also promote cell proliferation and neovascularization at the skin wound part, exert an anti-inflammatory effect, remodel skin microbiota and provide a more suitable microenvironment for skin wound healing. The invention provides a new drug choice for clinically repairing skin wounds, and can be used for developing new skin wound dressings.
Owner:GUANGDONG OCEAN UNIVERSITY

Acanthopanax acid polysaccharide with intestinal protection function and preparation method and application thereof

The application discloses a kind of acanthopanax acid polysaccharides with intestinal protection function and its preparation method and application, belong to the field of functional food and biotechnology.The acanthopanax acid polysaccharide is by water extraction alcohol precipitation, after impurity removal, through DEAE-52 anion exchange column elution and collection 0.2 mol / L NaCl elution peak, and the uniform component obtained by Sephadex G-100 gel column chromatography purification.Its uronic acid content is 30%-40%, weight average relative molecular weight is 50-100kDa, mainly by glucose, galactose, galacturonic acid and arabinose, infrared spectrum has carboxyl characteristic absorption peak at 1736 cm-1 and 1615 cm-1.Experiments prove that the acanthopanax acid polysaccharide has antioxidant activity and hypoglycemic activity.The acid polysaccharide has protective effect on LPS-induced Caco-2 cell damage, can effectively reduce the secretion of pro-inflammatory factors TNF-α, IL-1β, IL-6, and improve the level of anti-inflammatory factor IL-10.The acanthopanax acid polysaccharide can be prepared into oral liquid, tablet candy, solid beverage and other functional food forms.
Owner:NORTHEAST AGRICULTURAL UNIVERSITY

A sulfated arabinogalactan derived from *Streptococcus linearis*, its preparation method and application

This invention discloses an arabinogalactan sulfate derived from *Streptococcus filamentosa*, its preparation method, and its applications, belonging to the fields of natural product chemistry and marine biological resource development technology. The technical solution includes an arabinogalactan sulfate derived from *Streptococcus filamentosa*, with a monosaccharide composition comprising arabinose, galactose, and rhamnose, the molar percentage of arabinose being not less than 70%; the main chain backbone is modified with natural sulfate groups, with the sulfate groups replacing at least one hydroxyl site of the arabinose residues. This invention, when applied to anticoagulation, exhibits good safety and a significant anticoagulant effect.
Owner:SHANDONG ACAD OF MARINE SCI (QINGDAO NAT MARINE SCI RES CENT)

Lotus leaf homogeneous polysaccharide LLP3-1 as well as separation and purification method and application thereof

The invention discloses lotus leaf homogeneous polysaccharide LLP3-1 as well as a separation and purification method and application thereof, and belongs to the technical field of plant polysaccharide. The lotus leaf homogeneous polysaccharide LLP3-1 is composed of rhamnose, arabinose, galactose and galacturonic acid, the molar percentage of monosaccharide is 21.95: 25.33: 21.10: 31.62, the lotus leaf homogeneous polysaccharide LLP3-1 is acidic pectin polysaccharide with RG-I as a main structural domain and with part of side chains, the main chain is mainly composed of galacturonic acid and rhamnose, and the side chains are mainly composed of arabinose and galactose. The lotus leaf homogeneous polysaccharide LLP3-1 has the beneficial effects that the lotus leaf homogeneous polysaccharide LLP3-1 can obviously improve the symptoms of ulcerative colitis; the compound can be widely applied to preparation of medicines for treating ulcerative colitis, medicines for inhibiting proinflammatory factor secretion, antioxidation medicines, medicines for improving intestinal barrier integrity and functions, medicines for promoting short-chain fatty acid generation and medicines for improving intestinal flora disorder of ulcerative colitis.
Owner:JIANGXI NORMAL UNIV

Intumescent composion and intumescent product obtained therewith

PCT designated stageWO2026082882A1Fireproof paintsPolymer sciencePhosphate
Intumescent composition comprising an acid donor (A), a carbon donor (B), a binder polymer (C) and a blowing agent (D). The acid donor (A) is selected from the group consisting of ammonium polyphosphate, ammonium dihydrogen phosphate, ethylenediamine phosphate, ammonium pentaborate, guanylurea phosphate, diguanidine phosphate and mixtures thereof. The carbon donor (B) is selected from the group consisting of glucose, arabinose and other monosaccharides, lactose, maltose and other disaccharides, starch, cellulose, dextrin and other polysaccharides, sorbitol, erythritol, pentaerythritol, dipentaerythritol, mannitol and other polyhydric alcohols and mixtures thereof. The blowing agent is provided in the form of microsphere particles comprising a thermoplastic polymer shell encapsulating a propellant, which microsphere particles are expandable microspheres.
Owner:ETERNIT GMBH

A shoumei polysaccharide, a preparation method and application thereof

This invention provides a Shoumei polysaccharide, its preparation method, and its application, belonging to the field of biomedical technology. The Shoumei polysaccharide is a homogeneous polysaccharide with the repeating sequence →4)-α-D-Gal. p A‑(1→, →4)‑β‑D‑Gal p ‑(1→,→4,6)‑β‑D‑Gal p ‑(1→,→6)‑β‑D‑Gal p -(1→、α-L-Ara f ‑(1→,→5)‑α‑L‑Ara f ‑(1→,→4)‑β‑D‑Glc p -(1→; The molecular weight of the Shoumei polysaccharide is 1100 kDa; The monosaccharide composition of the Shoumei polysaccharide is arabinose, galactose, glucose and galacturonic acid; The molar ratio of arabinose, galactose, glucose and galacturonic acid is 10.9:12.1:4.8:72.2, and the degree of galacturonic acid esterification is 33%. The Shoumei polysaccharide of the present invention can treat and / or prevent depression.
Owner:ANHUI AGRICULTURAL UNIVERSITY

Application of Uncaria rhynchophylla neutral polysaccharide URP-W in the preparation of anti-glioma drugs

ActiveCN121005799Bachieve separationSolve the technical problems of extraction and separationOrganic active ingredientsNervous disorderCelluloseMonosaccharide composition
This invention discloses the application of Uncaria rhynchophylla neutral polysaccharide URP-W in the preparation of anti-glioma drugs, belonging to the field of anti-tumor technology of medicinal plant polysaccharides. The invention obtains a crude polysaccharide extract from Uncaria rhynchophylla through hot water extraction and ethanol precipitation, followed by purification using a DEAE cellulose column and G200 dextran gel to obtain Uncaria rhynchophylla neutral polysaccharide URP-W. The monosaccharide composition of URP-W includes arabinose, rhamnose, galactose, glucose, xylose, mannose, galacturonic acid, and mannuronic acid in a molar ratio of 17.99:6.32:21.71:27.17:2.56:7.57:16.20:0.49. Experiments have shown that URP-W can inhibit the proliferation of gliomas and induce apoptosis, exhibiting significant anti-tumor activity against glioma cells, providing a new drug raw material and treatment method for the clinical treatment of gliomas.
Owner:CHANGCHUN UNIV OF CHINESE MEDICINE

Ginseng polysaccharide, preparation method and application thereof

The application discloses a ginseng polysaccharide, a preparation method and application, and the ginseng polysaccharide is ginseng polysaccharide GP60, which is composed of glucose, galactose and arabinose, and the molar ratio of each monosaccharide is glucose: galactose: arabinose = 77.1: 16.8: 6.1; a new preparation method is adopted; after soaking and twice decocting, different proportions of 95% ethanol are added into the filtrate in batches; the obtained precipitate is added with water to prepare a solution with a relative density of 1.1 g / ml; a certain amount of the solution is taken, a certain proportion of chloroform and n-butanol is added, and a polysaccharide aqueous solution is prepared; the polysaccharide aqueous solution is added with 95% ethanol until the alcohol content reaches 60%; the solution is statically placed for 12 hours; centrifugal separation is carried out; the precipitate is collected; the collected precipitate is sequentially washed with 95% ethanol, anhydrous ethanol, isopropyl alcohol and ether; the solvent is volatilized; and the ginseng polysaccharide GP60 is obtained. The ginseng polysaccharide GP60 is non-toxic, has the effect of preventing light aging, and can be widely applied in the fields of food or health food, anti-light aging skin care products, washing and caring products and anti-light aging medicines.
Owner:BEIJING POLYTECHNIC

Xylose reductase XR21 mutant and application thereof

The invention relates to the technical field of enzyme engineering, in particular to a xylose reductase XR21 mutant and application thereof. Specifically, the invention provides a novel xylose reductase mutant aiming at the defect of poorer thermal stability of the existing wild type xylose reductase, and particularly provides a xylose reductase mutant which is obtained by performing single or multiple site amino acid mutation on the 19th site, the 48th site, the 79th site, the 208th site and the 300th site of a xylose reductase sequence shown as SEQ ID NO: 2, compared with wild type xylose reductase, the obtained xylose reductase mutant has the advantages that the activity of catalyzing an epimer substrate arabinose into arabitol can be obviously reduced, and meanwhile, the selectivity to xylose is improved, so that the operation process of downstream separation and purification is simplified, and the biological catalysis requirement of green industry is met.
Owner:浙江容锐科技有限公司

Kudouzi polysaccharide, and preparation method and application thereof

The application discloses Ixeris sonchifolia Hance polysaccharides, a preparation method and application thereof, belongs to the technical field of plant polysaccharides, and provides polysaccharides ISP-1a and ISP-2a, wherein the ISP-1a has a molecular weight of 2086 Da and is composed of seven monosaccharides of mannose, rhamnose, glucuronic acid, glucose, galactose, xylose and arabinose; the ISP-2a has a molecular weight of 1781 Da and is composed of five monosaccharides of mannose, rhamnose, galacturonic acid, xylose and arabinose. The whole grass of Ixeris sonchifolia Hance is subjected to hot water extraction after ethanol degreasing, neutral enzyme + Sevage method is used to remove protein, macroporous resin is used for decolorization, column chromatography elution is carried out, purification is carried out, and two kinds of uniform polysaccharides are obtained after freeze-drying. The polysaccharides ISP-1a and ISP-2a have good antioxidant and lipid-lowering effects, and can be applied to the preparation of food, health products or medicines with antioxidant and lipid-lowering functions.
Owner:SHENYANG PHARMA UNIV

Solanum lyratum homogeneous polysaccharide as well as preparation method and application thereof

The invention discloses solanum lyratum homogeneous polysaccharide as well as a preparation method and application thereof. The solanum lyratum homogeneous polysaccharide is mainly prepared from rhamnose, arabinose, galactose, glucose and galacturonic acid according to the molar ratio of 20.5: 20.6: 41.6: 2.2: 4.4, and the weight-average molecular weight of the solanum lyratum homogeneous polysaccharide is 7.0426 Kda. Soaking solanum lyratum thunb in water, decocting twice, combining filtrates, and carrying out rotary evaporation concentration; adding absolute ethyl alcohol into the concentrated solution while stirring, standing, and collecting bottom precipitate; redissolving the precipitate by using distilled water, and performing deproteinization treatment on a polysaccharide extracting solution obtained after redissolving by using a Sevag method to obtain a polysaccharide solution without an organic reagent; dialyzing the obtained polysaccharide solution by adopting a dialysis bag with the molecular weight of 3500Da to obtain a crude polysaccharide aqueous solution, and freeze-drying to obtain a solanum lyratum polysaccharide crude product; and separating and purifying the solanum lyratum polysaccharide crude product to obtain the solanum lyratum homogeneous polysaccharide. The solanum lyratum homogeneous polysaccharide prepared by the method has the advantages of fixed components, high yield, anticancer effect and good safety, and provides a basis for developing a potential new drug for colorectal cancer.
Owner:HENAN PROVINCE HOSPITAL OF TCM THE SECOND AFFILIATED HOSPITAL OF HENAN UNIV OF TCM +1

Radix sophorae tonkinensis polysaccharide STGP-1, preparation method thereof and pharmaceutical use for treating lung squamous carcinoma

The application discloses radix sophorae tonkinensis polysaccharide STGP-1, a preparation method thereof and pharmaceutical use for treating lung squamous carcinoma, and relates to the technical field of medicines. The monosaccharide composition of STGP-1 includes fucose Fuc, arabinose Ara, galactose Gal, glucose Glc, xylose Xyl and mannose Man, and the molar ratio is 0.34:12.15:25.76:57.07:1.06:3.62. The STGP-1 is obtained by extraction, separation and purification from dried roots and rhizomes of radix sophorae tonkinensis, and the preparation method comprises the steps of pretreatment and crude extraction, impurity removal treatment, anion exchange column chromatography separation, gel column chromatography purification and the like. The STGP-1 can be used alone or in combination with anti-PD-1 monoclonal antibody for preparing a medicine for treating lung squamous carcinoma. The preparation process is stable, the source is natural, and the STGP-1 can provide a new high-efficiency and low-toxicity candidate medicine for immune combined treatment of lung squamous carcinoma.
Owner:GUANGXI MEDICAL UNIVERSITY

Preparation method and equipment of composition helpful for controlling absorption of carbon water

The invention provides a preparation method and equipment of a composition helpful for controlling carbon water absorption. According to the preparation method, the phyllanthus emblica, the sugarcane polyphenol, the white kidney bean extract, the mulberry leaf extract and the L-arabinose are respectively embedded by adopting chitosan nanoparticles, so that the stability of active ingredients is improved, and fixed-point release of intestinal tracts is realized. And uniformly mixing the obtained embedded particles, protein powder, dietary fibers and other raw materials through a three-dimensional mixing machine, and carrying out composite molding on the obtained mixture and a sugar-oil mixture to prepare the high-protein meal replacement bar which plays a role in synergistically controlling sugar and promoting lipid metabolism. According to the preparation equipment, an auxiliary mixing assembly is additionally arranged in a mixing barrel and comprises a guide bearing rod distributed along a barrel shaft and an auxiliary mixing part capable of sliding along the guide bearing rod, the mixing barrel moves to drive the auxiliary mixing part, and meanwhile reciprocating sliding is achieved through the gravity effect. According to the structure, the powder overturning and dispersing effects are enhanced, agglomeration is effectively broken, the mixing uniformity and stability are improved, and the mixing efficiency is remarkably improved under the condition of low energy consumption.
Owner:ZHEJIANG NUTRIEASE CO LTD

A specific targeted method to eliminate bladder without leaving scars. KPC-2 Gene and IncL plasmid sgRNA sequences, CRISPR / Cas9 system and applications

PendingCN122081324ABacteriaHydrolasesOrigin of replicationConserved sequence
This invention belongs to the field of bioengineering technology and discloses a method for specific targeting and scarless simultaneous elimination blue KPC‑2 Gene and IncL plasmid sgRNA sequences, CRISPR / Cas9 vector system and applications. This system targets the sgRNA of the IncL plasmid. blue KPC‑2 The IncL-type plasmid of the gene was designed with an sgRNA that specifically recognizes the conserved sequence at its origin of replication, thus eliminating the drug resistance gene while disrupting the plasmid's replication ability. Conjugation transfer to recipient bacteria significantly improved vector delivery efficiency. An arabinose-inducible promoter was used to control Cas9 gene expression, improving system stability and editing success rate. The vector carries a sucrose-inducible self-eliminating gene, enabling controlled vector self-elimination. This system is not a simple superposition but rather constitutes a time-controlled operational flow: efficient delivery via conjugation, controlled cleavage via induction, and finally, induced self-elimination.
Owner:KUNMING UNIV OF SCI & TECH

Caulis spatholobi polysaccharide, preparation method thereof and application of caulis spatholobi polysaccharide in preparation of medicine for treating inflammation

The invention belongs to the technical field of plant polysaccharide, and particularly discloses caulis spatholobi polysaccharide, a preparation method thereof and application of the caulis spatholobi polysaccharide in preparation of medicines for treating inflammation. Monosaccharide in the caulis spatholobi polysaccharide disclosed by the invention comprises mannose, glucuronic acid, galacturonic acid, glucose and arabinose in a molar ratio of (0.5-0.6): (0.3-0.5): (1-2): (1-2): (0.5-1.5). The caulis spatholobi polysaccharide provided by the invention is a novel uniform-structure polysaccharide which is separated from caulis spatholobi rattan for the first time, has a slightly acidic pH value, definite monosaccharide composition, definite molecular weight and clear glycosidic bond linking mode, has an anti-inflammatory effect, and is expected to be developed into a new anti-inflammatory drug. The preparation process is mild in condition, simple to operate and environment-friendly.
Owner:ANHUI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE

Tabletting candy capable of inhibiting fat absorption and preparation method thereof

The invention provides a tablet candy capable of inhibiting fat absorption and a preparation method of the tablet candy, and relates to the technical field of functional foods. The pressed candy capable of inhibiting fat absorption comprises 0.1-25 parts of flammulina velutipes powder, 1-18 parts of L-arabinose, 0.05-5 parts of carob gum, 0.1-12 parts of chestnut powder, 0.1-10 parts of seaweed meal, 0.1-10 parts of instant oolong tea powder, 1-15 parts of composite vegetable powder, 30-80 parts of sorbitol, 3-15 parts of whole milk powder, 0.1-10 parts of edible mushroom concentrated powder, 1-10 parts of yoghurt powder, 1-15 parts of juicy peach juice powder and 0.1-2 parts of citric acid. And 0.1 to 1.5 parts of magnesium stearate. Various functional components such as beta-glucan and L-arabinose in the flammulina velutipes have a synergistic effect, so that the fat adsorption rate is increased; by means of the cold granulation and low-temperature tabletting technology, the retention rate of active ingredients is increased, meanwhile, the product has excellent stability and safety and good taste, the effects of improving intestinal flora and regulating blood sugar can be achieved, and important technical value and wide application prospects are achieved.
Owner:SHANGHAI BAIXIANXIAN BIOTECHNOLOGY CO LTD

Salicornia polysaccharide, and preparation method and application thereof

The application discloses a Salicornia polysaccharide as well as a preparation method and application thereof. The Salicornia polysaccharide is composed of 11 kinds of monosaccharides, wherein arabinose (24.96%), galactose (30.39%) and galacturonic acid (23.20%) are main monosaccharides of the polysaccharide, and the relative molecular weight is 3.24*10 4 Da. The Salicornia polysaccharide has a very special surface morphological structure, and presents a regular sawtooth distribution. The anti-tumor activity of the Salicornia polysaccharide is researched, and it is found that the polysaccharide can inhibit the growth of HepG2 cells, and the molecular mechanism of the anti-tumor activity is that the polysaccharide can induce the apoptosis of HepG2 cells. The Salicornia polysaccharide has significant anti-tumor activity, can be used as a candidate drug for developing an anti-tumor drug, and has a wide development prospect.
Owner:YANCHENG INST OF TECH

Keemun'an tea polysaccharide ANTP-1 for improving insomnia and preparation method of Keemun'an tea polysaccharide ANTP-1

The invention discloses Keemun'an tea polysaccharide ANTP-1 for improving insomnia and a preparation method thereof, and belongs to the field of separation and purification of plant active ingredients. The Keemun'an tea polysaccharide ANTP-1 is prepared from mannose, rhamnose, glucose, galactose, xylose and arabinose, the molar ratio of the mannose to the rhamnose to the glucose to the galactose to the xylose to the arabinose is 1.00: 0.36: 16.78: 1.96: 4.50: 8.21, and the relative molecular weight of the Keemun'an tea polysaccharide ANTP-1 is 26.58 kDa. The Keemun'an tea polysaccharide ANTP-1 disclosed by the invention can be used for remarkably shortening the sleep latency period of a sleep deprivation mouse, prolonging the sleep duration and effectively improving insomnia. The Keemun'an tea polysaccharide ANTP-1 disclosed by the invention is clear in composition and remarkable in effect, and has a wide development and application prospect in the aspect of aiding sleep.
Owner:ANHUI UNIV +1

Sugarcane leaf polysaccharide composition for regulating intestinal flora function and application thereof

The present application belongs to the technical field of sugarcane leaf polysaccharide regulating intestinal flora. The present application provides a sugarcane leaf polysaccharide composition, which comprises mannose, rhamnose, glucuronic acid, galacturonic acid, glucose, galactose, xylose, arabinose and fucose in a mass ratio of 6.8:1.5:5.2:40.7:13.1:18.9:1.6:6.1:1.9. The composition of the present application can improve the imbalance of intestinal flora caused by obesity and hyperglycemia by reducing the ratio of Firmicutes / Bacteroidetes and increasing the abundance of probiotics.
Owner:INST OF MICROBIOLOGY CHINESE ACAD OF SCI

Sulfated arabino-oligosaccharides, methods for their preparation and uses thereof

PendingCN122277628APyranoseBackbone chain
This invention discloses a sulfated arabinoglycoside, its preparation method, and its applications, belonging to the field of biomedical technology. The technical solution includes a sulfated arabinoglycoside derived from *Streptococcus linearis* polysaccharide; a degree of polymerization of 2-5; arabinose as the main monosaccharide, and containing galactose; the molar percentage of arabinose is not less than 80%, and the molar percentage of galactose is not more than 20%; the main chain is composed of (1→4)-β-L-pyranose arabinose groups, with the sulfate groups of the arabinose mainly substituted at the C-3 position. This invention is applied to inhibiting the abnormal aggregation of human pancreatic islet amyloid peptide (hIAPP), solving the problem of the lack of safe and effective intervention methods for the abnormal aggregation of human pancreatic islet amyloid peptide in existing technologies. It features stable raw material sources, high safety, a simple and mild preparation method suitable for large-scale preparation, and the ability to inhibit the abnormal aggregation of human pancreatic islet amyloid peptide and reduce pancreatic β-cell damage.
Owner:SHANDONG ACAD OF MARINE SCI (QINGDAO NAT MARINE SCI RES CENT)

High-activity polygonatum polysaccharide as well as preparation method and application thereof

The invention provides high-activity polygonatum polysaccharide as well as a preparation method and application thereof, and belongs to the technical field of effective component extraction. A mixture of cellulase, hemicellulase and pectinase is used as a compound enzyme preparation for enzymolysis, extraction and purification to obtain the polygonatum polysaccharide PCPA. The molecular weight of the polygahatous polysaccharide PCPA is 1372 Da, the polygahatous polysaccharide PCPA is composed of three monosaccharides of arabinose, glucose and fructose, the molar ratio of the three monosaccharides is 0.39: 6.48: 93.13, and the polygahatous polysaccharide PCPA has the effects of delaying cell senescence and improving cell repair activity.
Owner:GUOZHEN HEALTH TECH (BEIJING) CO LTD

Escherichia coli strain capable of bidirectionally regulating CoIE1 type plasmid copy number and application thereof

PendingCN121699822ABacteriaHydrolasesBinding siteOperon
The invention discloses an Escherichia coli strain capable of bidirectionally regulating the copy number of CoIE1 type plasmids and application of the Escherichia coli strain. According to the method, escherichia coli Mach1-T1 is taken as an initial strain, a CRISPR / CAS9 gene editing technology is utilized, RNase E Q36R variant genes, rssB genes and pcnb genes are constructed into a polycistron expression cassette, and the polycistron expression cassette is placed under the control of an arabinose operon to replace endogenous pcnb genes of a genome. Each gene in the polycistron expression cassette is driven to translate by an independent ribosome binding site (RBS). By adjusting the concentration of the arabinose, continuous and bidirectional regulation and control of the copy number of the CoIE1 type plasmids from'inhibition 'to'overproduction' can be realized, and the method has important significance on industrial mass production of the CoIE1 type plasmids and diversified application of the CoIE1 type plasmids.
Owner:SUZHOU HONGXUN BIOTECH CO LTD

Nine-steaming and nine-processing polygonatum sibiricum homogeneous polysaccharide as well as preparation method and application thereof

The invention belongs to the technical field of traditional Chinese medicine extraction, and relates to a nine-steamed nine-processed rhizoma polygonati homogeneous polysaccharide and a preparation method and application thereof, in particular to a nine-steamed nine-processed rhizoma polygonati homogeneous polysaccharide and a preparation method and application thereof. The purpose of the invention is to determine one component in the nine-steamed nine-processed polygonatum sibiricum product. NPCP-A1 is extracted by a water extraction and alcohol precipitation method, deproteinized by a Sevag method, and subjected to chromatographic separation and purification by a DEAE-52 anion exchange column and a Sephacryl S-300 gel column, and the NPCP-A1 is prepared from arabinose, rhamnose, galactose, glucose, xylose, mannose, galacturonic acid and glucuronic acid. The proliferation of RAW264.7 cells and the secretion of NO, TNF-alpha and IL-6 can be promoted. The composition is used for preparing health-care products or medicines for improving immunity. According to the acidic polysaccharide prepared by the method disclosed by the invention, the polysaccharide plays an immune regulation role by promoting macrophage proliferation and increasing secretion of cell factors such as NO, TNF-alpha, IL-6 and the like.
Owner:HEILONGJIANG ACAD OF TCM

Inonotus obliquus acidic polysaccharide IOP-2 with anti-thyroid cancer activity and application thereof

The application discloses a chaga acidic polysaccharide IOP-2 with anti-thyroid cancer activity and application thereof, and belongs to the field of biological medicines. The application adopts a method for extracting chaga polysaccharide by boiling water and precipitating chaga polysaccharide by ethanol, and combines DEAE cellulose column purification technology, and successfully realizes separation of chaga polysaccharide by using the principle that macromolecular polysaccharide is insoluble in organic solvents, and obtains chaga acidic polysaccharide IOP-2 with anti-thyroid cancer activity. The monosaccharide composition of the chaga acidic polysaccharide IOP-2 includes fucose 0.71%, rhamnose 3.33%, arabinose 2.18%, galactose 2.92%, glucose 80.59%, xylan 3.46% and mannose 6.81% in terms of molar percentage. The significant effect of the chaga acidic polysaccharide IOP-2 on anti-thyroid cancer is verified through in-vivo and in-vitro experiments, and a new treatment method is provided for clinical treatment of thyroid cancer.
Owner:CHANGCHUN UNIV OF CHINESE MEDICINE

Solid fuel, method for firing solid fuel, and method for producing solid fuel

To provide a solid fuel that contains biomass while suppressing fouling. [Solution] The present invention provides a solid fuel comprising biomass char and pulverized coal, wherein, when the total amount of the biomass char and pulverized coal in an oven-dry state is taken as 100% by mass, the biomass char content is 3 to 90% by mass, and the pulverized coal content is 10 to 97% by mass, and in the biomass char, the mannose content as constituent sugars is 2.0 to 12.0% by mass, the xylose content is 0.3 to 10.0% by mass, the arabinose content is 1.0% by mass or less, and the glucose content is 40.0 to 55.0% by mass, and the ash content of the pulverized coal is 20 to 40% by mass on an oven-dry basis.
Owner:MITSUBISHI UBE CEMENT CORP

Lactobacillus paragasseri and application thereof

The present application relates to the field of microorganism, discloses a lactobacillus paragasseri and application thereof. The lactobacillus paragasseri with the preservation number CGMCC No.36335 provided by the present application can metabolize multiple non-digestible carbohydrates, especially xylo-oligosaccharides, resistant starch, arabinose and mucin, and realize growth and reproduction by taking these substances as the only carbon source; can relieve constipation, and has the application prospect of preparing preparations for defecation; can produce high-yield lipoteichoic acid, and has the application value for industrial production of lipoteichoic acid.
Owner:COFCO NUTRITION AND HEALTH RESEARCH INSTITUTE CO LTD +1

A bio-based dust suppressant useful for road stabilization

This invention relates to the field of road dust suppression technology, specifically to a bio-based dust suppressant that can be used for road reinforcement. Based on 100% solid content, it contains the following components in the following weight ratio: 100 parts xylose mother liquor and 3-50 parts polyamine crosslinking agent; wherein the xylose mother liquor contains 20%-70% solids by weight, with the remainder being water; wherein the solids contain ≥50% reducing sugars by weight, including D-xylose, L-arabinose, D-glucose, and D-galactose, and the xylose content in the solids is ≥20%. The dust suppressant obtained by this invention uses a large amount of waste xylose mother liquor, a byproduct of the sugar industry. This product is a renewable resource and a low-carbon renewable product. Furthermore, the dust suppressant obtained by this invention not only has dust suppression function but also good compressive strength and water resistance, and can be used as a soil stabilizer. Applying the dust suppressant of this invention to roads can produce a pavement system with excellent overall performance.
Owner:JIANGSU AKST NEW MATERIALS CO LTD