74 results about "Pentose" patented technology

The invention discloses lactobacillus pentosus capable of converting various substances of dendrobium officinale to generate rich active small molecules and improving skin health, and belongs to the technical field of microorganisms. The lactobacillus pentosus (Lactobacillus pentosus) CCFM1482 obtained by screening can be used for producing various active substances by fermenting dendrobium officinale and regulating and controlling the synthesis of skin collagen factors, such as HSF cells (human skin fibroblasts), MDA (malondialdehyde), Nrf2 (nuclear factor E2 related factor 2) and HaCaT cells (human keratinocytes). Therefore, the lactobacillus pentosus CCFM1482 fermented dendrobium officinale kimura ex migo fermentation liquor has a huge application prospect in the preparation of products for preventing or treating the skin quality, and the dendrobium officinale kimura ex migo fermentation liquor can be used for preparing the products for preventing or treating the skin quality.

The invention relates to the technical field of synthetic biology, in particular to a squalene high-yield saccharomyces cerevisiae engineering bacterium and a construction method and application thereof.Saccharomyces cerevisiae CEN.PK.2-1D is used as an original strain, pentose phosphate pathway genes ZWF1, GND1, TAL1 and TKL1 and IDP1 genes of TCA circulation are integrated in a genome of the original strain through homologous recombination, and the squalene high-yield saccharomyces cerevisiae engineering bacterium is obtained. Constructing a dual-channel cofactor supply system to improve the intracellular NADPH level and the NADPH / NADP + ratio; according to the saccharomyces cerevisiae genetic engineering strain Sc-Sq04 constructed by the method disclosed by the invention, the yield of squalene obtained by shake flask fermentation reaches 741.08 + / -28.9 mg / L by further integrating all genes of an MVA way, ERG20 and ERG9 genes, and a new thought is provided for transforming saccharomyces cerevisiae to synthesize terpene compounds and promoting industrial application.

This invention belongs to the field of food fermentation technology, and specifically relates to a compound probiotic agent and its application in the preparation of fermented soy milk. This invention provides a compound probiotic agent composed of *Lactobacillus fermentum* NCPS LF01, *Pediococcus pentosaceus* NCPS PPE01, and *Lactobacillus acidophilus* NCPS LA01 in a volume ratio of 1-2:1:1, and applies this compound probiotic agent to the preparation of soy products, especially fermented soy milk. The beneficial effects of this invention are that fermented soy milk prepared using this compound probiotic agent has a rich flavor, and the total flavonoid and total phenolic content, as well as the in vitro DPPH free radical scavenging rate, are significantly superior to those of ordinary commercially available strains or other strains. In summary, this compound probiotic agent can effectively improve the retention level of active ingredients and antioxidant capacity of fermented soy milk, and has outstanding application value.

The invention belongs to the technical field of food fermentation, and provides a naan air-holding aroma-enhancing rapid fermentation composite leavening agent and a preparation method, the composite leavening agent comprises freeze-drying type lactobacillus plantarum, freeze-drying type saccharomyces cerevisiae, freeze-drying type pediococcus pentosaceus, lactobacillus rhamnosus, lactobacillus casei and Xiangba powder, and the optimal mass ratio of the freeze-drying type lactobacillus plantarum, the freeze-drying type saccharomyces cerevisiae, the freeze-drying type pediococcus pentosaceus, the lactobacillus rhamnosus, the lactobacillus casei and Xiangba powder is 2: 1: 3: 2: 3: 1 or 3: 1: 3: 1: 2: 2. The crusty pancake prepared according to the proportion has better sensory characteristics, specifically, the crusty pancake tastes softer and more elastic, the surface glossiness is improved, and the color is more uniform and natural. In addition, the method can also shorten the fermentation time, and endows the product with unique aroma of the sour dough fermented crusty pancake, thereby enhancing the flavor of the final product. The problems that the taste and the flavor are single when commercial yeast is independently used for making the fermented crusty pancake are solved, and the problems that when traditional sour dough is used for making fermented flour products, the fermentation time is long, the stability is poor, the quality is difficult to control, harmful microorganisms are prone to breeding and the like are solved.

This invention provides a method for the co-production of organic acids and lignin from lignocellulose, comprising the following steps: Step 1, pretreating the lignocellulose raw material to obtain a pretreated material; Step 2, enzymatically hydrolyzing the pretreated material to obtain an enzymatic hydrolysate containing pentoses, hexoses, and lignin; Step 3, performing solid-liquid separation on the enzymatic hydrolysate to obtain an enzymatic hydrolysate containing pentoses and hexoses and a solid phase containing lignin; Step 4, subjecting the enzymatic hydrolysate containing pentoses and hexoses to acid-producing fermentation to obtain a fermentation broth containing a mixture of organic acids; Step 5, extracting lignin from the lignin-containing solid phase to obtain lignin. The method provided by this invention can efficiently separate lignin and obtain various organic acids through a simple process.

Cosmetic products containing specific amounts of adenosine and at least one pentose in a cosmetic carrier are suitable for the treatment of hair and / or scalp and lead to - Revitalization of the hair and / or - Stimulation / activation of energy metabolism in hair follicles / hair roots and / or - Stimulation / enhancement of hair growth and / or - Prevention / reduction of premature hair loss and / or - Delaying scalp aging and / or - Increased keratin synthesis and / or - Improvement of the tensile strength of keratin fibers.

The application discloses a preservative for reducing the content of polycyclic aromatic hydrocarbons in meat products and application thereof. The preservative comprises Lactobacillus pentosus R3, the Lactobacillus pentosus R3 is preserved in the China General Microbiological Culture Collection Center (CGMCC), the preservation number is CGMCC No. 26346, and the preservation date is December 27, 2022. The preservative is inoculated on the surface of the meat product, the growth of spoilage microorganisms can be inhibited, fat oxidation of the meat product is delayed, the shelf life of the smoked meat product is prolonged, the content of polycyclic aromatic hydrocarbons in the smoked meat product can be significantly reduced, and the food safety is improved.

The present disclosure provides genetically engineered microorganisms for the simultaneous fermentation of pentose and hexose sugars, for example, glucose and xylose. The microorganisms can be modified to express AtSWEET polypeptides, LST1 polypeptides, mutants thereof, homologs thereof or combinations thereof. Also provided are methods of co-fermenting hexose and pentose sugars, methods of increasing the conversion of lignocellulosic biomass via microbial fermentation, and methods of generating biofuel.

This invention aims to address the technical bottlenecks of existing milk curd products, such as weak functional activity, unclear process parameters, and unstable flavor and quality. It utilizes *Pediococcus pentosaceus* HM4, *Streptococcus thermophilus* HM6, *Lactococcus lactis* JY4, and *Lactobacillus plantarum* NC1, employing these four strains in an optimal ratio as a compound fermentation agent to achieve synergistic effects. Using milk and goji berries as raw materials, the fermentation process of milk curds and goji berry milk curds was systematically optimized through single-factor experiments, Plackett-Burman experiments, and response surface methodology. The physicochemical indicators and flavor characteristics of the products under different process conditions were analyzed. The obtained milk curds achieved a DPPH free radical scavenging rate of 91.38%–94.15%, providing technical support for the high-value utilization of milk curds and enriching the variety of functional dairy products.

The application provides a preparation method of a composite water-retaining agent and application of the composite water-retaining agent in fermented meat products. The composite water-retaining agent is composed of a basic water-retaining agent and water-retaining microspheres. Components of the basic water-retaining agent include glutamine transaminase, trehalose, L-histidine and gellan gum, and the basic water-retaining agent plays a water-retaining role in a curing period; the water-retaining microspheres are prepared by embedding L-cysteine and reduced glutathione in Pediococcus pentosaceus fermented pineapple leaves as wall materials and vehiclepsin seed gum, and slowly release active substances under acid triggering in a late fermentation period, thereby playing a water-retaining role. The application provides a non-phosphorus composite water-retaining agent with better comprehensive performance than composite phosphate and commercial non-phosphorus water-retaining agents, significantly improves water-retaining property without interfering with fermentation, and provides a green, efficient and non-phosphorus special water-retaining solution for fermented meat products.

The application discloses a composition with soothing and itching-relieving effects and a preparation method and application thereof, and belongs to the cosmetic field; the composition comprises the following components: a composite plant extract, a polyhydric alcohol and water; the composite plant extract is compounded by a polygonatum sibiricum redoute fermentation liquor, a paeonia extract and a long-stemmed grape caulerpa lentillifera extract; and the polygonatum sibiricum redoute fermentation liquor is obtained by composite fermentation of lactobacillus pentosus and bacillus subtilis. The soothing and itching-relieving composition provided by the application has excellent soothing effects, and the soothing and itching-relieving composition provided by the application has excellent in-vitro hyaluronidase inhibition effects, and the in-vitro hyaluronidase inhibition rate reaches more than 60%.

The present application relates to a kind of pentose pediococcus and the preparation method of fermented whey.The present application provides a kind of pentose pediococcus IF2, on December 31, 2025, is preserved in Guangdong Microbial Culture Collection Center, and the preservation number is GDMCC No:67584.The strain is isolated from Xinjiang yogurt, with good whey adaptability and flavor promotion capacity.After the single bacteria fermentation whey, the content of dimethyl disulfide, dimethyl trisulfide in whey can be significantly reduced, while the content of acetaldehyde and other flavor compounds is greatly improved, and fermented whey is given apple fragrance.Sensory evaluation shows that the overall preference score of fermented whey can reach 4.6 points, and the flavor is significantly improved.

The invention relates to a method for synthesizing an alkyl glycoside surfactant by a one-step process, which solves the problem that the residual quantity of glucose in a product material obtained by the existing one-step process for synthesizing the alkyl glycoside surfactant is high, and adopts the technical scheme that the method for synthesizing the alkyl glycoside surfactant by the one-step process comprises the following steps of: in the presence of an acid catalyst and an additive, adding a catalyst, alkyl alcohol and carbohydrate are subjected to an aldolization reaction to obtain a product material containing alkyl glycoside, the additive molecule comprises at least one selected from the group consisting of triose alcohol, butyl sugar alcohol, pentitol and hexitol, and the carbohydrate comprises glucose. The addition of the additive reduces the residual amount of glucose in the product material.

This invention relates to a method for preparing polylactic acid (PLA) by straw fermentation coupled with lactide ring-opening polymerization, belonging to the field of biomass resource utilization and bio-based polymer materials technology. To address the problems of high energy consumption and low sugar conversion rate in existing PLA preparation methods using crop straw, this invention provides a method for preparing PLA by straw fermentation coupled with lactide ring-opening polymerization. The method involves crushing the straw, pre-treating it with dilute acid coupled with steam explosion, washing and drying it, adding a complex cellulase and Lactobacillus pentosus LB-1 seed culture, and simultaneously saccharifying and fermenting under controlled temperature and pH to obtain a lactic acid fermentation broth. The fermentation broth undergoes multi-stage filtration, ion exchange, and concentration to obtain refined lactic acid, which is then prepolymerized, depolymerized, and distilled to obtain L-lactide. After purification, an initiator and antioxidant are added, and ring-opening polymerization, extraction, and drying are performed under nitrogen protection to obtain pure PLA. This invention features efficient and low-energy straw pretreatment, high sugar-acid conversion rate during fermentation, precise purification, stable polymerization, and low cost, making it a green and economical method using straw as raw material.

The invention relates to pediococcus pentosaceus CAR6 for improving carotenoid, protein peptide and plant-based flavor and application of the pediococcus pentosaceus CAR6. The preservation number of the pediococcus pentosaceus CAR6 is CGMCC (China General Microbiological Culture Collection Center) The strain has the acid stability fermentation characteristic, can avoid the problem of over-acidification caused by over-fermentation, can efficiently synthesize short-chain fatty acids such as organic acid and butyric acid, has good agglutination and self-agglutination capacity, oxidation resistance and SOD enzyme secretion capacity, and has a remarkable bacteriostatic effect on streptococcus mutans, staphylococcus aureus and shigella sonnei. When the carrot fermentation broth is applied to carrot fermentation, earthy smell and grass smell of raw materials can be effectively removed, the sensory flavor of a fermented product is remarkably improved, meanwhile, the content of carotenoid, total protein and polypeptide is increased, and the content of glucose is reduced. The strain provides a new bacterium source for fermentation of carrots and other plant-based products, and has important application value in development of flavor fermentation products, eye protection, sugar control, protein peptide and intestinal tract conditioning type healthy nutritional food.

The application belongs to the technical field of biomass catalytic conversion, and specifically discloses a gallium-modified dealuminized H-ZSM-5 catalyst, a preparation method and application thereof, and the method comprises the following steps: ion exchange is performed on Na-ZSM-5 molecular sieve and an ammonium salt solution; selective dealuminization is performed on NH4-ZSM-5 molecular sieve and an ammonium hexafluorosilicate solution; and the impregnation method is used to load a gallium salt solution to the dealuminized molecular sieve carrier DeAl-H-ZSM-5, so as to obtain the gallium-modified dealuminized H-ZSM-5 catalyst. The application adopts the above-mentioned gallium-modified dealuminized H-ZSM-5 catalyst, the preparation method and application thereof, and the method is characterized in that the composite strategy of purifying the base by selectively dealuminizing first and then precisely loading Ga to regulate the acidity is adopted, the prepared catalyst can efficiently catalyze the preparation of furfural from pentose in a γ-valerolactone / water system, and high conversion rate and high selectivity are realized.

The application belongs to the technical field of livestock and poultry meat product processing safety, and specifically discloses a low-sodium nitrite ham and a preparation method thereof.The raw material of the ham comprises pork and a pickling liquid.The pickling liquid comprises 0.01 g / kg-0.05 g / kg of sodium nitrite, 1.0 wt%-3.0 wt% of salt, 2 mL / kg-10 mL / kg of a compound probiotic bacteria liquid, and 1.0 wt%-2.0 wt% of a hawthorn-wolfberry compound extract.The compound probiotic bacteria liquid comprises Pediococcus pentosaceus MJ11 and Lactobacillus pentosus GM09.The pickling liquid can inhibit the synthesis of nitrosamine in the ham and reduce the content of nitrosamine.Therefore, the ham prepared by using the pickling liquid has the advantages of low sodium nitrite and stable quality.

The application discloses a Pediococcus pentosaceus strain derived from high-temperature Daqu and application thereof, the strain is named Pediococcus pentosaceus zqw75, and the preservation number is CGMCC NO.25146.The strain can produce aroma substances such as lauryl acetate, n-heptanol, butyl dodecalactone, benzene acetaldehyde, methyl heptenone and pyrazine, and when the strain is used in combination with commercial sweet wine starter, the relative content of phenylethanol is increased from 8.562% to 10.455%, the relative content of ethyl butyrate is increased from 0.460% to 1.473%, the relative content of ethyl octanoate is increased from 0.754% to 1.672%, the relative content of ethyl n-hexanoate is increased from 0.832% to 3.446%, and the relative content of isoamyl acetate is increased from 0.832% to 2.155%; and the strain can produce aroma substances that are not produced by the commercial sweet wine starter, such as hexanoic acid, butyric acid, octanoic acid, ethyl hexanoate and lauryl acetate.The strain can be applied in the field of liquor making, including pit mud making and liquor flavor substance improvement, and has great industrial application value.

A natural synergistic brewing method for Stachys aegypti, belonging to the field of food processing technology; addressing the problems of existing Stachys aegypti pickles relying on chemical preservatives, long fermentation cycles, high nitrite risk, and easily becoming soft and mushy, this invention provides a natural synergistic brewing method, comprising: mixing rosemary, green tea, cloves, and water in a mass ratio of (2~4):(1~3):1:100, and ultrasonically extracting to obtain a natural plant extract; adding a commercially available compound bacterial agent containing Lactobacillus plantarum and Pediococcus pentosaceus to a mixture of 2% glucose water and the extract. In the mixed solution, activate at 35-37℃ for 25-35 minutes; place the pretreated *Spiritobacterium tumefaciens* in 4%-5% saline solution, inoculate with 3%-5% activated bacterial solution by weight of saline solution, soak at 25-28℃ for 2-4 days, and then soak at 8-10℃ for 4-6 days; after testing, the finished product was found to contain no chemical preservatives such as benzoic acid and potassium sorbate, nitrite <1mg / kg, brittleness value reached 13.8N, and it has a unique herbal fragrance, achieving low-salt, rapid, and high-brittleness natural fermentation.

The invention provides a technical method for producing high-purity linalool based on a microbial fermentation method, which is characterized in that a linalool synthase gene is modified and edited based on an AlphaFold gene through sgRNA design and carrier construction, strain transformation and gene cleavage verification, glucose is combined as a core carbon source, and a yeast extract and peptone are selected as nitrogen sources, so that the high-purity linalool is produced. The method comprises the following steps of: preparing a basic culture medium, subculturing to obtain a target strain, improving the linalool synthase performance, realizing the iterative optimization of the efficient strain, preparing and sterilizing a fermentation culture medium, inoculating the strain, starting fermentation, monitoring and regulating fermentation parameters in real time, automatically adjusting the parameters and the like to realize a fermentation reaction to obtain linalool. According to the method, the linalool synthase is taken as a raw material, key precursor substances such as acetyl coenzyme A and pentose phosphate are added, and a proper amount of inducer and cofactor are introduced, so that the linalool synthase catalytic efficiency of the strain is enhanced, the problems of low fermentation yield, high separation and purification cost, poor large-scale production stability and the like at present are effectively solved, and green biological production of high-purity linalool is realized.

This invention relates to a process, a plant, and a biofuel for integrated biofuel production, such as with butanol, biodiesel, and / or sugar product. The integrated process includes the step of removing hexose from a feedstock to form a lignocellulosic material. The process also includes the step of converting the hexose to butanol and / or a biodiesel material, and the step of depolymerizing lignocellulosic material to form pentose and a residue. The process also includes the step of converting the pentose to butanol and / or a biodiesel material.

The present invention relates to a variant microorganism for producing 1,3-propanediol and a 1,3-propanediol production method using same. More specifically, genes of a microorganism are modified and recombined to produce 1,3-propanediol, by improving the citric acid cycle (TCA cycle) and the glycoxylate pathway in a strain having improved pentose phosphate (PP) and Entner-Doudoroff (ED) pathways. Therefore, a high concentration of 1,3-propanediol may be produced by using the variant microorganism according to the present invention.

This invention discloses an engineered bacterial strain for producing xylitol using glucose as the sole carbon source, its construction method, and its applications, belonging to the field of genetic engineering. Using *Escherichia coli* as the starting strain, this invention optimizes the metabolic pathway by knocking out the 2-keto-3-deoxy-6-phosphate glucuronide gene (eda), knocking out the 6-phosphoglucuronide dehydratase gene (edd), and weakening the glucose phosphoisomerase gene (pgi), thus concentrating the carbon flow in the pentose phosphate pathway. Furthermore, it optimizes the metabolic pathway by knocking out or overexpressing endogenous genes such as the ribulokinase gene (araB). Subsequently, the synthesis of xylitol from glucose was experimentally tested by expressing a recombinant expression plasmid containing 2-arabinol dehydrogenase, 4-arabinol dehydrogenase, and xylitol dehydrogenase. This invention, through optimized metabolic pathways, efficiently converts glucose to xylitol without the need for glycerol addition, and significantly increases the yields of both the precursor arabinol and the product xylitol, demonstrating promising production prospects.

This invention relates to mutant microorganisms for producing 1,3-propanediol and a method for producing 1,3-propanediol using the same. Specifically, the invention involves recombining the genes of microorganisms to enhance the TCA cycle and glycoxylate pathway in strains that strengthen the PP pathway (pentose phosphate pathway) and ED pathway (Entner-Doudoroff pathway), thereby enabling the production of 1,3-propanediol. Therefore, high concentrations of 1,3-propanediol can be produced using the mutant microorganisms according to the invention.

The invention discloses a metabiotic strain with dietary cholesterol adsorption capacity in small intestines as well as a preparation method and application of the metabiotic strain, the metabiotic strain comprises one of lactobacillus plantarum LSJ-TY-HYB-T7, lactobacillus fermentum LSJ-TY-HYB-L16 and lactobacillus pentosus TY-HYB-SYY-Y3, and the metabiotic strain comprises one of lactobacillus plantarum LSJ-TY-HYB-L16 and lactobacillus pentosus TY-HYB-SYY-Y3. And the lactobacillus plantarum LSJ-TY-HYB-T7, the lactobacillus fermentum LSJ-TY-HYB-L16 and the lactobacillus pentosus TY-HYB-SYY-Y3 are all in an inactivated state. Research finds for the first time that the metabiotic strain disclosed by the invention does not generate an adsorption effect in a gastric juice environment, but can specifically and efficiently adsorb dietary cholesterol in intestinal juice, efficiently block small intestines from absorbing the dietary cholesterol, reduce the levels of total cholesterol, low-density lipoprotein and triglyceride in mice, and inhibit the growth of the dietary cholesterol in the mice. And the adsorbed dietary cholesterol is discharged out of the body together with excrement after being fermented by the colon.

The invention belongs to the technical field of fermented feed, and particularly relates to a compound lactic acid bacterium agent for producing yak feed by fermenting highland barley vinasse, and application and an application method thereof. The invention provides a compound lactic acid bacterium agent for producing yak feed by fermenting highland barley vinasse, which is prepared by compounding bacterium liquid of lactobacillus plantarum, bacterium liquid of lactobacillus buchneri, bacterium liquid of lactobacillus fermentum and bacterium liquid of pediococcus pentosaceus according to the volume ratio of (2-4): (1-3): (1-3): (0.5-2). Cellulose components in the raw materials such as the highland barley vinasse, the alfalfa hay and the rapeseed cake can be fully decomposed, so that the utilization rate of the raw materials is greatly improved, and meanwhile, the content of nutritional ingredients such as crude protein in the fermented feed and the oxidation resistance of the feed are improved; a new way is provided for development of the yak industry and improvement of the additional value of the highland barley vinasse.

A method for efficiently extracting hemicellulose from brewer's spent grains and selectively hydrolyzing it to prepare pentoses is disclosed, relating to the comprehensive utilization of biomass resources and the food chemical industry. 1) Alkaline extraction: The spent grains are mixed with NaOH solution, ultrasonically extracted, and then subjected to a water bath. The reaction solution is separated, acid-precipitated, and alcohol-precipitated to obtain crude hemicellulose. 2) Acid hydrolysis: The crude product is mixed with sulfuric acid solution and hydrolyzed under heating to obtain a hydrolysate rich in xylose and L-arabinose. The optimal combination of process parameters was determined through single-factor and synergistic optimization: Alkaline extraction: 3% NaOH, 1:8 solid-liquid ratio, 60℃, 1.5h; Acid hydrolysis: 1.5% H2SO4, 1:12 solid-liquid ratio, 130℃, 60min. The pentose yield per gram of spent grains reaches 182–198 mg, the xylose yield is 41.3%–42.8%, and the furfural formation rate is less than 1.5%. This method achieves efficient and high-value conversion of hemicellulose from spent grains, and the process is simple and environmentally friendly.

This application relates to the fields of bioengineering and fermentation technology, and discloses a genetically engineered *Escherichia coli* strain that synthesizes L-histidine and its preparation method. The engineered strain uses *Escherichia coli* W3110 as the starting strain and is modified... hisG Gene release from feedback inhibition; knockout ushA and nrdD Genes reduce precursor consumption; inactivation slyA Genes reduce energy waste; heterogeneous integration zwf and gnd Genes and replacement pgi The gene promoter redirects carbon flow to the pentose phosphate pathway, enhancing the supply of key precursors PRPP and reducing agent NADPH; introducing courtE Genes promote product efflux. Combined with an optimized fed-batch fermentation process, this invention effectively solves the problems of insufficient precursor supply, uneven energy distribution, and product inhibition through a systems metabolic engineering strategy, increasing L-histidine yield and sugar-acid conversion rate, making it suitable for industrial production.

The present invention relates to a binder composition comprising a) Component A comprising amino acid polymer(s) A1 and b) Component B comprising component B1 selected from the group consisting of pentoses, hexoses, disaccharides of pentoses and / or hexoses and mixtures thereof, wherein the amino acid polymer(s) A1 has(have) a total weight average molecular weight Mw,total of at least 800 g / mol and at most 10.000 g / mol and wherein the binder composition comprises at least 55 wt.-% amino acid polymer(s) A1 based on the total weight of the amino acid poly- mer(s) A1 and component B1.

The invention relates to the technical field of medical preparations, and discloses application of a composition in preparation of a medicine for preventing and / or relieving hangover, the composition is composed of calcium beta-hydroxy-beta-methylbutyrate (CaHMB), probiotics and prebiotics; the probiotics comprise at least one of pediococcus pentosaceus, lactobacillus rhamnosus, lactobacillus casei and bifidobacterium longum; the prebiotics comprise at least one of fructo-oligosaccharide, galactooligosaccharide, xylooligosaccharide, inulin, polydextrose and resistant dextrin; the composition with the hangover preventing and / or relieving effect and a pharmaceutically acceptable carrier are used for preparing a preparation for preventing and relieving hangover, and the preparation comprises an injection, a freeze-dried powder injection, an ointment, a spray or an oral preparation. The liver injury induced by alcohol can also be effectively improved.