582 results about "Terpene" patented technology

The invention belongs to the technical field of biological medicine, and particularly relates to a luliconazole composition containing essential oil, cream and a preparation method and application of the luliconazole composition. The present application provides a composition containing tea tree essential oil that promotes the skin permeability of luliconazole and has an antibacterial function, the tea tree essential oil and luliconazole form a synergistic antifungal effect, the transdermal absorption is enhanced by a natural terpene component, and the irritation to the skin is significantly reduced.

An electronic vaporizer for vaporizing liquids is provided herein featuring a cylindrical, glass reservoir tank within a non-cylindrical case. The glass reservoir tank may reside between a detachable mouthpiece disposed at an upper section of the case and a lower section of the case that houses the interior components of the electronic vaporizer including the atomizer, battery, circuit board, and heating element comprising a heating wire and a cotton-free ceramic bucket. The reservoir tank may further include at least one tube providing an air flow passage that may be made of glass. The at least one tube may extend between the mouthpiece and the heating element. Based upon the cylindrical, glass reservoir tank within the non-cylindrical case, the electronic vaporizer may provide a desirable oxidation of vape oils within the glass reservoir tank while maintaining the desired taste of the vape oil, depending the terpene content of the vape oil.

Provided is a plant activator with which it is possible to safely, stably, and effectively promote an increase in fruiting by appropriately spraying the activator onto plants or using the same for irrigation. The plant activator contains: at least one compound selected from an oxo fatty acid or a derivative thereof or a salt thereof; and a terpene.

The invention discloses a preparation process of a pure plant essential oil disinfectant, and relates to the technical field of disinfectants. The problems that plant essential oil is poor in solubility in a water phase, low in stability and the like are solved. The method specifically comprises the following steps: preparing raw materials; preparing a nano emulsion; preparing a solvent and mixing; constructing a natural stable system to obtain a primary product; filtering and sterilizing; and carrying out sterile filling on the disinfectant finished product. The invention provides a pure plant essential oil disinfectant prepared by dissolving type 1 and 8 melaleuca alternifolia essential oil in water, efficient dispersion is realized through a nano-emulsification and natural stabilization technology so as to form a stable aqueous solution, an amphiphilic structure of soapbark saponin is utilized, aglycone and essential oil terpene form a supramolecular compound, and the stable aqueous solution can be used for sterilizing the melaleuca alternifolia essential oil and the melaleuca alternifolia essential oil and the melaleuca alternifolia essential oil. The technical problems of poor dissolvability and low stability of plant essential oil in a water phase are solved, and the plant essential oil has broad-spectrum antibacterial and antiviral characteristics and can meet the disinfection requirements in multiple fields such as medical treatment, object surface treatment, home furnishing and personal care.

The invention relates to the technical field of microorganisms, in particular to saccharomyces cerevisiae CEC NRI16 and application thereof. The invention provides Saccharomyces cerevisiae CEC NRI16, which is used for wine brewing, can significantly improve the variety aroma and the content of ester substances and terpene substances in dry white wine, especially can promote the generation of ethyl acetate, isoamyl acetate, ethyl hexanoate, ethyl caprate and linalool, reduces the generation of isoamyl alcohol, and improves the yield of wine. The grape wine presents richer fragrance of green fruits such as pears and apples and fragrance of flower fragrance such as violet and roses, and the raw and green taste is effectively reduced. The yeast strain is strong in fermentation capacity and excellent in fermentation performance, and has great value in the aspects of maintaining the typicality of grape wine varieties and enhancing flavor characteristics.

The application belongs to the technical field of genetic engineering, and discloses a kind of saccharomyces cerevisiae for producing rare ginsenoside by seaweed biomass and a construction method and application thereof.The saccharomyces cerevisiae has the following characteristics: overexpression of agarase, neojuncanohydrolase, hydroxymethylglutaryl coenzyme A reductase, isopentenyl diphosphate delta isomerase, dammaradienol synthase, protopanaxadiol synthase, cytochrome P450 reductase, protopanaxatriol synthase and glycosyltransferase.The application combines enzymolysis of seaweed biomass with fermentation of rare ginsenoside, which not only endows wild-type yeast with the ability to degrade seaweed biomass that it originally does not have, but also effectively improves the yield of squalene and downstream terpenes (rare ginsenoside Rh1) by overexpression of tHMG1 and IDI1.The saccharomyces cerevisiae can effectively utilize seaweed biomass to obtain squalene and rare ginsenoside Rh1, and has the characteristics of simplicity, economy and ecological friendliness, can convert cheap biomass into high-value products, and provides a way for the development of marine bioeconomy.

The invention discloses a waterborne polyurethane adhesive and a preparation method thereof, and belongs to the technical field of high polymer materials. The waterborne polyurethane adhesive provided by the invention comprises a main agent and a curing agent, and most of raw materials of the main agent and the curing agent are waterborne materials, such as a waterborne polyurethane dispersion, a waterborne acrylic emulsion, a waterborne EVA emulsion, a waterborne rosin resin emulsion, a waterborne terpene resin emulsion and waterborne isocyanate. Due to the water-based materials, the adhesive has the characteristics of low VOC (volatile organic compounds), zero formaldehyde and low odor. Moreover, the water-based isocyanate in the curing agent and the active hydroxyl in the main agent component can be subjected to addition polymerization reaction to form a cross-linked network polymer, so that the adhesive has relatively high cohesiveness and can meet the bonding requirement of the automotive trim.

The invention discloses an environment-friendly odorless sealing strip adhesive as well as preparation and application thereof, and the environment-friendly odorless sealing strip adhesive is prepared from the following components in parts by mass: 15 to 20 parts of polyacrylate resin, 10 to 15 parts of dammar resin, 5 to 10 parts of fir resin, 3 to 5 parts of hydrogenated terpene resin, 2 to 5 parts of tributyl citrate and 45 to 65 parts of n-decane. The preparation method comprises the following steps: uniformly mixing natural resin (dammar resin, fir resin and hydrogenated terpene resin), polymeric monomers (n-octyl acrylate, methyl methacrylate and hydroxyethyl acrylate) and an environment-friendly solvent (n-decane), and then polymerizing to obtain the environment-friendly adhesive. The synthetic resin (polyacrylate resin) and the natural resin are sufficiently and mutually dissolved in n-decane to form stable and uniform composite resin glue, so that the problems of health risk and environmental pollution caused by harmful solvents such as xylene in the traditional sealing glue are effectively avoided, and the characteristics of no toxicity, no odor and environmental protection of the product are realized; meanwhile, the stability and the bonding performance of the section sealing glue are improved, the matching performance of the optical transmittance and the refractive index of the section sealing glue is enhanced, and the section sealing glue has quick-drying performance and is suitable for medical pathological sections.

The invention belongs to the technical field of biosynthesis, and particularly relates to a method for regulating and controlling stevioside production through a UDPG synthesis route. According to the invention, a high-efficiency stevioside biosynthesis system is constructed through systematic engineering modification: in the aspect of chassis cell optimization, transcription factors (AtWRKY18, AtWRKY40 and AtMYC2) for regulating and controlling MEP pathway and key genes (dxs and / or dxr) of the MEP pathway are over-expressed, so that supply of terpene precursors is enhanced; and a heterologous MVA pathway (over-expression T7-atoB-mvaS-mvaE-mvK / mvKmut-pmK-mvaD-idi) with a modular design is introduced, so that sufficient supply of the terpenoid precursor is realized. Meanwhile, the intracellular concentration of the UDPG is increased by systematically enhancing a UDPG synthesis pathway (knocking out ugd, glgc, ushA, agp, deoA, tdk, udp, or thrA, and overexpressing galU, pgm, pyrE, pyrH, ugpA, or prs), so that the production capacity of the stevioside is remarkably improved.

The invention belongs to the technical field of biosynthesis, and particularly relates to a method for regulating and controlling stevioside production by improving the utilization rate of a carbon source. According to the invention, a high-efficiency stevioside biosynthesis system is constructed through systematic engineering modification: in the aspect of chassis cell optimization, transcription factors (AtWRKY18, AtWRKY40 and AtMYC2) for regulating and controlling MEP pathway and key genes (dxs and / or dxr) of the MEP pathway are over-expressed, so that supply of terpene precursors is enhanced; and a heterologous MVA pathway (over-expression T7-atoB-mvaS-mvaE-mvK / mvKmut-pmK-mvaD-idi) with a modular design is introduced, so that sufficient supply of the terpenoid precursor is realized. Meanwhile, by knocking out related genes and bypass metabolism genes (mgsA, iclR, menA or adhE) synthesized by organic acid, a glucose transport and utilization system (fnr, fadR, ppc, zwf or pgi is knocked out, and ACS, fbaA, tpiA, glf, galP or ptsG is overexpressed, so that the utilization rate of a carbon source is further improved, and the production capacity of stevioside is remarkably improved.

The invention relates to a lead-free and halogen-free soldering paste and a preparation process thereof, and belongs to the technical field of soldering paste production, through the combination of nano-silver-loaded carbon nanotubes, organically coated solder alloy powder and soldering flux, the surface tension of the lead-free and halogen-free soldering paste can be reduced by carbon nanotube surface carboxyl in the nano-silver-loaded carbon nanotubes, so that the lead-free and halogen-free soldering paste is obtained. Nano-silver and tin form an Ag3Sn strengthening phase which synergistically promotes wetting and spreading of the solder on a substrate, meanwhile, the carbon nanotubes loaded with the nano-silver are uniformly dispersed in the soldering paste to play a dispersion strengthening role, and the brittleness caused by bismuth segregation is effectively inhibited in cooperation with the grain refinement effect of copper and indium in the solder alloy powder; and the organic coating layer hydrogenated rosin-terpene resin and the soldering flux alcohol ether solvent form a slight dissolution-fusion effect, so that the welding flux alloy powder is prevented from being oxidized, an organic acid active agent can be released to remove a substrate oxidation film, the metallurgical bonding quality of a welding interface is further guaranteed, and the defects of pseudo soldering, cavities and the like are reduced.

The invention relates to the technical field of air purifying materials, in particular to a negative oxygen ion air purifying agent and a preparation method thereof.The negative oxygen ion air purifying agent is prepared from ethyl cellulose, hydroxyethyl acrylate, citric acid activated bentonite, beta-cyclodextrine, neodymium-doped tourmaline powder, modified plant essential oil, propylene glycol and carboxymethylcellulose. Sodium polyaspartate and a pH buffer agent. According to the invention, through a triple technology of terpene-free essential oil selection, metal ion modification and beta-cyclodextrin coating, the problem of negative ion consumption of traditional essential oil is avoided, and the release amount and durability of negative oxygen ions are remarkably improved through a catalytic synergistic effect.

Described are liquid compositions that contain a desired (e.g., extracted) plant material such as cannabinoid, terpene, terpenoid, or the like, contained, e.g., dissolved, suspended, or emulsified, in the liquid, which contains surfactant; methods of preparing these types of liquid compositions; and methods of processing this type of liquid composition to collect, isolate, concentrate, or purify a desired target material contained in the liquid composition.

The invention belongs to the field of microbial fermentation, and particularly discloses a method for fermenting astragalus membranaceus by lactobacillus plantarum. The method comprises the following steps: S1, crushing and sterilizing astragalus membranaceus; s2, inoculating lactobacillus plantarum LP-301; and S3, carrying out fermentation culture. After astragalus membranaceus is fermented by the lactobacillus plantarum LP-301, the contents of substances such as flavonoids, quinones and terpenes in a fermentation product are remarkably increased, so that the lactobacillus plantarum LP-301 can be used for preparing antioxidant products or anti-inflammatory products and has a relatively high application value.

The invention discloses a lactobacillus brevis SMF L6 strain for improving the characteristic flavor of fermented fish and application thereof, and belongs to the technical field of aquatic product processing. According to the method disclosed by the invention, low-temperature fermentation is carried out by utilizing a sake lactobacillus wide cloth SMF L6 direct vat set fermentation inoculant to regulate and control the flavor; the method can effectively promote the production of flavor substances such as n-hexyl alcohol, eudesmol, 2-ethylhexyl alcohol, 4-platycladi alcohol, linalool, 4-terpene alcohol, alpha-terpilenol, piperonone, beta-myrcene, alpha-terpinene, D-limonene, beta-phellandrene, gamma-terpinene and the like in the fermented fish. The content of pungent smell and fishy smell substances such as acetic acid, p-xylene, o-xylene, trimethylamine, methyl mercaptan and carbon disulfide is reduced.

To provide a silicone release agent composition having lower odor than conventional one.SOLUTION: There is provided a silicone release agent composition which comprises (A) 83 to 99.5 pts.mass of a linear, branched or cyclic organopolysiloxane having at least two alkenyl group-containing organic groups in one molecule and 0.001 to 0.20 mol of an alkenyl group in 100 g of an organopolysiloxane, (B) a polyorganohydrogensiloxane having at least three SiH groups in one molecule in an amount such that the ratio of the number of moles of SiH groups in the component (B) to the number of moles of alkenyl groups in the component (A) is 0.6 to 20, (C) a platinum group metal-based catalyst in a catalytic amount, (D) 1 to 20000 pts.mass of at least one solvent selected from terpene and a terpene derivative based on 100 pts.mass of the total of the components (A), (B) and (C), and (E) 0.5 to 10 pts.mass of an addition reaction controlling agent based on 100 pts.mass of the total of the components (A), (B) and (C).SELECTED DRAWING: None

A method of plant extraction comprising: (a) providing a plurality of trichomes from a plant at a first temperature below about 35 °C; and either: (b1) applying a negative pressure to the trichomes to volatize at least one desired compound from the trichomes to form a gaseous plant extract; and (c1) condensing the gaseous plant extract at a second temperature below about 25 °C to form a liquid plant extract; or (b2) combining the trichomes with a fluid to form a mixture; (c2) inducing cavitation in the mixture to release at least one desired compound from the trichome into the fluid; and (d2) separating out the at least one desired compound from the mixture; wherein the at least one desired compound is a terpene, a terpenoid, a cannabinoid, or a flavonoid.

This easily dismantlable adhesive sheet (100) comprises an adhesive layer (10) containing a moisture-cured product of a silyl group-containing resin and a terpene phenolic tackifying resin, wherein the silyl group-containing resin has a polyoxyalkylene structure in a main chain, has, in a portion of the main chain or a side chain, both bonds among a urethane bond and a urea bond or one bond among the urethane bond and the urea bond, and has hydrolyzable silyl groups represented by formula (1) at both ends of the main chain. (In formula (1), X1 and X2 are each independently a hydroxy group or an alkoxy group, R is a C1-C20 alkyl group, and * is a bonding position.)

Compositions which are fragrant and contain at least a member set culled from a library of compositions, each being comprised of sub-combinations of selected terpenes. Fragrances that mimic that of various states of organic and synthetic aromatics including products, processes and those from non-combusted plant products, among other things, uniquitous products, processes, medicinals, and related moieties leverage databases of all known terpene groupings are offered for consideration, and have been provided, according to the instant teachings.

The invention discloses a composition for enhancing Chinese chestnut fragrance of a tea beverage as well as a preparation method and application of the composition, and belongs to the technical field of food additives. The composition is prepared from the following raw materials in parts by weight: 0.1 to 0.9 part of furanone, 0.01 to 0.2 part of linalool, 0.001 to 0.5 part of 2, 5-dimethylpyrazine, 0.02 to 0.1 part of geraniol, 0.03 to 0.05 part of beta-ionone and 0.01 to 0.25 part of geranyl acetone. According to the invention, through a unique ratio design, the scorched nut smell of pyrazine compounds, the rich caramel sweet taste of furanone, the stir-fried smoke and fire smell of 2-acetylthiazole and the freshness of geraniol and other terpene alcohols are ingeniously fused, and the complex level of Chinese chestnut fragrance is accurately reproduced. According to the present invention, the edible-grade propylene glycol is adopted as the solvent, such that the solubility, the dispersibility and the stability of the aroma composition in the tea beverage can be effectively improved, the persistence and the uniformity of the aroma release can be significantly improved, the shelf life of the tea beverage product can be easily prolonged, and the market competitiveness of the product can be enhanced.

Preparations and uses of a Lemna extract derived from duckweed are disclosed. These extracts comprise complex blends of volatile and non-volatile compounds, including aromatic compounds such as phenols, flavonoids, and certain terpenes. The extract may contain other constituents such as carbohydrates (e.g. pectin), proteins, fibers, vitamins, minerals, antioxidants, and fatty acids. The Lemna extract composition has properties that make it suitable as a food additive, odorless and flavorless (by itself but it has the ability to enhance other products properties). In an embodiment, when applied to food products (both beverages and solids), the extract effectively masks undesirable aftertastes, modulates and enhances flavors, and / or improves mouthfeel, thereby serving as an excellent food flavor modifier. Various Lemna extracts demonstrate unique functionalities, such as extending melting times, enhancing the quality of ice cream, and intensifying sweetness, further highlighting its versatility as a food modifier.

This invention provides a breathable plaster matrix for application and its preparation method, belonging to the field of polymeric dressings and plasters. The plaster matrix raw materials include terpene-modified rosin beeswax, hydrogenated rosin glyceryl ester, camellia oil, castor oil, stearic acid hydrophobically modified microcrystalline cellulose, zinc oxide, glycerin, coated citric acid, sodium bicarbonate, polyethylene glycol, camphor, and menthol. The terpene-modified rosin beeswax is prepared by reacting rosin and α-pinene in the presence of di-tert-butylperoxyisopropylbenzene, followed by the addition of white beeswax and maleic anhydride, and then the addition of trimethylolpropane. The stearic acid hydrophobically modified microcrystalline cellulose is microcrystalline cellulose coated with stearic acid. The coated citric acid is citric acid coated with hydrogenated castor oil. This invention's plaster matrix significantly improves skin breathability, application comfort, and biocompatibility while ensuring sufficient adhesion, formability, and drug loading capacity.

A liquid composition containing, as a sucrose fatty acid ester in liquid form, a sucrose fatty acid ester in which the constituent fatty acid has 16 or more carbon atoms, the liquid composition comprising terpenes and a monohydric alcohol and / or a dihydric alcohol, wherein the content of the terpenes is 0.08-1.2 parts by weight relative to 1 part by weight of the sucrose fatty acid ester, the content of the monohydric alcohol and / or the dihydric alcohol is 0.50-5.0 parts by weight relative to 1 part by weight of the sucrose fatty acid ester, and the content of the sucrose fatty acid ester is 15-80% by weight of the total amount of the liquid composition.

The invention relates to the technical field of sealing glue for shoes, and discloses environment-friendly traceless sealing glue for shoes and a preparation method of the environment-friendly traceless sealing glue. The sealing compound is prepared from 40 to 50 parts of polyester polyol, 9 to 15 parts of HDI (hexamethylene diisocyanate) tripolymer, 0.1 part of environment-friendly catalyst, 2 to 5 parts of silane coupling agent, 1 to 1.5 parts of organic silicon flatting agent, 15 to 20 parts of ethyl acetate / acetone mixed solution and 8 to 10 parts of hydrogenated rosin glyceride and terpene resin. The sealing compound disclosed by the invention has the characteristics of traceless invisibility, high-strength adhesion, good leveling performance, wide applicability and environmental protection.

The invention discloses a method for retaining flavor of plum-leaf crab ice wine. The method comprises the following steps: 1, selecting red-pulp malus spectabilis fruits and eight-edge malus spectabilis fruits, washing, and draining with a vibrating screen until the surface moisture is less than or equal to 5%; 2, denucleating, taking pulp, pulping and sieving to obtain plum-leaf crab normal juice; 3, beta-glucosidase is added; 4, adding modified pectin microspheres, and carrying out three-stage cooling to obtain frozen plum-leaf crab normal juice; 5, slowly unfreezing, inoculating low-temperature-resistant saccharomyces cerevisiae liquid, and carrying out low-temperature segmented fermentation; 6, ageing; and 7, adding potassium tartrate, continuing for 2-3 months, filtering, and clarifying until the turbidity is less than or equal to 2NTU. The modified pectin microspheres with the adsorption-slow release function are added, terpene and ester flavor precursors in the plum-leaf crab are adsorbed in the fermentation period, the volatilization and hydrolysis rate of flavor substances in the fermentation process is reduced, especially the retention rate of plum-leaf crab characteristic fruity substances such as ethyl caprylate and ethyl caprate can be increased, and after being degraded, the modified pectin microspheres can be used for degrading the plum-leaf crab characteristic fruity substances. And the components are released back into the wine body.

The application provides an oily environment-friendly high-molecular anticorrosive waterproof coating and a preparation method thereof, and belongs to the technical field of coating compositions. The oily environment-friendly high-molecular anticorrosive waterproof coating is prepared from the following raw materials in parts by weight: SEPS 5-20 parts, polyisobutylene 1-15 parts, terpene resin 3-15 parts, poly-alpha-methylstyrene resin 1-12 parts, A81 resin 2-10 parts, inorganic filler 7-50 parts, defoaming agent 0.1-2 parts, antioxidant 0.1-2 parts, ultraviolet absorber 0.1-2 parts, light resistance agent 0.1-1 part, environment-friendly solvent 25-70 parts, and perfume 0-1 part. The oily environment-friendly high-molecular anticorrosive waterproof coating is waterproof, corrosion-resistant, environment-friendly and convenient to construct, and is suitable for application in surface protection of color steel tile and the like.

The invention relates to the technical field of wine brewing, and discloses a preparation method of a viburnum macrocephalum pulp sweet white wine, which comprises the following steps: accurately harvesting viburnum macrocephalum pulp grapes, simultaneously removing diseased fruits and green fruits, treating the picked viburnum macrocephalum pulp grapes by adopting an air bag squeezing process, and then carrying out low-temperature clarification treatment to obtain grape juice. According to the preparation method of the viburnum macrocephalum pulp sweet white wine, through low-temperature squeezing and special yeast low-temperature fermentation processes, the retention rate of core terpene aroma substances of the viburnum macrocephalum pulp is larger than or equal to 90%, the finished product is rich in aroma, the attenuation rate of the aroma within the shelf life of 24 months is smaller than or equal to 15%, and the preparation method is far superior to a traditional process; the problem of low natural acidity of the Jones-dried scallop pulp is solved, residual sugar and acidity form golden balance, and the Jones-dried scallop pulp is full in sweet taste but not greasy; the palatability score is improved by 50% or above compared with that of a traditional process; through oak barrel aging process innovation, the finished product can present various flavor structures, the limitation of single flavor of a traditional product is broken through, and the high-end attribute is remarkable.

The invention relates to the technical field of feeds, in particular to a feed for improving mutton quality and a preparation method and application thereof. The feed comprises the following raw material components in parts by weight: 50-65 parts of concentrated feed; 35-50 parts of a coarse material; 1-8 parts of rose dregs; the concentrate is selected from one or more of corn, sorghum, wheat, fodder soybeans, peas, broad beans, soybean meal, cottonseed meal, rape seed cakes and peanut oil cakes; the coarse material is selected from alfalfa, leymus chinensis, awn of wheat, elymus dahuricus, cotton leaves, crop straws and chaff shells; according to the total mass of the rose flower residues, the rose flower residues contain 15 to 18 weight percent of flavone, 12 to 16 weight percent of terpenes, 9 to 13 weight percent of alkaloid, 5 to 9 weight percent of sugar and alcohol and 5 to 9 weight percent of amino acid. The feed provided by the invention can improve the growth performance of fattening sheep, also can improve the tenderness of longissimus dorsi of mutton and the content of amino acids and unsaturated fatty acids in the mutton, and improves the sense organ and quality of the mutton.

The invention discloses a method for improving the processing quality of tobacco leaves by using a facultative anaerobic bacterium compound preparation, which comprises the following steps: preparing seed solutions of bacillus altitudinis ZY02-1, bacillus subtilis SMXP-58 and klebsiella variicola HNYJ-3, preparing a tobacco extracting solution, compounding the seed solutions according to the ratio of 2: 1: 2, centrifuging, resuspending and culturing by using the tobacco extracting solution to obtain a compound bacterial agent, and preparing the compound bacterial agent by using the facultative anaerobic bacterium compound preparation. And finally, spraying the complex microbial inoculant according to the inoculum size of 2-5% until the primarily-cured tobacco leaves are dampened until the moisture content is 14-15%, sealing, stacking and fermenting at 20-30 DEG C for 3-5 days, and then re-drying. By means of the method, decomposition of polyphenol and terpene aroma precursors of the tobacco leaves can be accelerated, the content of aroma substances such as megastigmatrienone is remarkably increased, aroma components such as oxidized isophorone are added, the aroma quality and the aroma amount of cigarettes are improved, offensive odor is reduced, and the aftertaste and smoking comfort are improved.

The invention relates to a recombinant genetically engineered bacterium for synthesizing terpenoids. The recombinant genetically engineered bacterium is saccharomyces cerevisiae in which a gal80 gene, an lpp1 gene and a dpp1 gene are knocked out and a heterologous MVA pathway gene and an AuoblA gene are integrated. According to the invention, a ophiobollin synthesis route is introduced into the saccharomyces cerevisiae in a heterologous manner for the first time, so that de novo synthesis of a ophiobollin skeleton compound, namely the ophiobollin F and an oxidation product of the ophiobollin F is realized; the synthesis of the ophiobolin F of 5.1 g / L is realized, which is also the highest sesterterpene heterologous synthesis yield reported at present; according to the invention, the ophiobolin 5-OH-21-CHO-opF with a new structure, which has excellent anti-cancer activity, is obtained through identification; the engineering strain of high-yield ophiobolin U is constructed, and the shake flask yield reaches 128.9 mg / L.