156 results about "Bisabolol" patented technology

The invention belongs to the technical field of personal hygiene products, and particularly relates to a nursing wet tissue which comprises a non-woven fabric body and formula production liquid, and the front end of the non-woven fabric body is provided with an opening; the formula production liquid comprises the following components: glycerol, propylene glycol, menthol, PEG-40 hydrogenated castor oil, benzalkonium chloride, phenoxyethanol, an aloe vera leaf extract, citronella oil, eucalyptus oil, bisabolol, G2833 (S) Baogoli LW-210060 and the balance of deionized water, wherein the total percentage of the components is 100%. According to the nursing wet tissue, in a sports scene, the nursing wet tissue can be fixed during use through the design of the opening and is prevented from sliding off; volatile oil components in menthol and peppermint oil in the formula production liquid can penetrate into the skin and act on pores, the pores can be effectively shrunk, the aperture of the pores is reduced, and therefore the chance that external dirt and grease enter the pores is reduced.

The present invention discloses a yeast engineering bacterium containing a (-)-α-bisabolol synthase mutant and its application. By designing (-)-α-bisabolol synthase, the present invention obtains a mutant with high expression level, co-expresses the mutant with ERG20, highly expresses the key rate-limiting enzymes in the metabolic pathway, deletes the promoter to reduce the side reaction pathway, and adopts a multi-copy strategy to improve the metabolic flux in the (-)-α-bisabolol biosynthesis pathway. The shake-flask fermentation yield of the yeast engineering bacterium constructed by the present invention is close to 70 mg / L, which is about 35 times higher than that of the starting strain, and has broad application prospects in the biological fermentation production of (-)-α-bisabolol.

The invention relates to a light loss repairing composition for improving skin resistance and application of the light loss repairing composition, and belongs to the technical field of cosmetics. The light loss repairing composition for improving the self resistance of the skin comprises the nannochloropsis oculata extract, the butterflybush flower extract and the bisabolol, all the components have a synergistic effect, ultraviolet light and blue light can be protected, and the light loss repairing composition has an anti-light aging effect and can be used for repairing the self resistance of the skin. And the mask has the effects of repairing skin barrier, relieving skin inflammation, improving redness, preventing hyperpigmentation, resisting aging, tightening skin, improving skin state and the like, and has the effect of improving self resistance of the skin.

The invention provides a composition and cream with anti-inflammatory and skin barrier injury repairing effects as well as a preparation method and application of the composition and cream, and belongs to the technical field of skin injury repairing. The invention provides a composition with anti-inflammatory and skin barrier injury repairing effects. The composition is prepared from matrine, dipotassium glycyrrhizinate, bisabolol and asiaticoside according to the weight ratio of 1: 1: 1: 1. The composition provided by the invention can play a role through a multi-target mechanism, such as up-regulation of Invoucrin, and provides a more effective prevention and treatment scheme for skin barrier dysfunction related diseases and sensitive skin.

The present invention belongs to the field of cosmetics technology, specifically to a sunscreen and whitening composition, its preparation method, and its application. The present invention utilizes a combination of various functional ingredients, including ethylhexyl triazone, diethylamino hydroxybenzoyl hexyl benzoate, bis-ethylhexyloxyphenol methoxyphenyl triazine, niacinamide, glabridin, ascorbic acid derivatives, sodium hyaluronate, bisabolol, dipotassium glycyrrhizate, aloe vera juice, squalane, Chuanxiong extract, and Scutellaria baicalensis extract, to synergistically block UVA and UVB rays across the entire wavelength range and provide five-fold benefits: sunscreen, whitening, moisturizing, soothing, and repairing. This addresses the problem of many products on the market that offer only sunscreen without whitening and skincare benefits, providing effective skincare and protection.

The invention discloses cosmetic oil with whitening, soothing and anti-aging effects and a preparation method of the cosmetic oil. The plant essential oil is prepared from the following raw materials in parts by weight: 0.5 to 1.5 parts of sunflower seed oil, 0.01 to 0.05 part of lupinus albus seed extract, 0.0001 to 0.001 part of tocopherol, 0.01 to 0.05 part of rosemary leaf extract, 0.001 to 0.1 part of dimethyl methoxy benzodihydropyranol, 50 to 90 parts of caprylic / capric triglyceride, 0.01 to 0.2 part of ascorbyl tetraisopalmitate, 0.01 to 0.2 part of bisabolol, 5 to 20 parts of squalane, 2 to 8 parts of simmondsia chinensis seed oil, 5 to 15 parts of meadowfoam seed oil and 0.1 to 1 part of lavender oil. And 0.3-1 part of a centella asiatica extract. According to the cosmetic oil product provided by the invention, by optimizing the use of substances, the composition has triple effects of whitening, relieving and resisting aging, can meet multiple skin care requirements of consumers at the same time, and is wide in market application range.

The invention belongs to the technical field of cosmetics, and relates to a multichannel multi-target accurate delivery anti-allergy soothing nano-composite and a preparation method and application thereof, glycyrrhizic acid, bisabolol, 4-tert-butyl cyclohexanol and hydroxyphenyl propionamide benzoic acid are selected as anti-allergy soothing functional components. Comprising the following raw materials in percentage by mass: 0.1-5wt% of glycyrrhetinic acid; 0.1 to 10 weight percent of bisabolol; 0.001 wt% to 1 wt% of 4-tert-butyl cyclohexanol; 0.01 to 1 wt% of hydroxyphenyl propionamide benzoic acid; 10 to 50 wt% of an emulsifier; 1 to 20 wt% of a liquid lipid; 1 to 10 wt% of a co-emulsifier; 10 to 30 wt% of a polyol; and the balance of water. The sum of the mass percentages of the components is 100%. According to different passages of different active ingredients, the four active ingredients are simultaneously loaded in the same composition, so that multi-passage and multi-target accurate delivery can be realized, the skin can be timely and efficiently relieved from the source, the uncomfortable symptoms of the skin can be solved, and the immunity of the skin can be improved.

The invention discloses a wet tissue liquid for improving hemorrhoid symptoms, a wet tissue, a production method and application, the wet tissue liquid comprises asiaticoside, a sophora flower charcoal extract, bisabolol, a honeysuckle flower extract, a rosemary extract, ceramide NP, D-panthenol, potassium cocoyl glycinate, citric acid, sodium citrate and purified water, and the wet tissue comprises spunlace non-woven fabric. The wet tissue liquid is loaded on a non-woven fabric, the production process of the wet tissue liquid comprises a pretreatment stage, a preparation stage and a filtering stage, and the produced wet tissue liquid is applied to hygienic products for improving hemorrhoid symptoms. The sophora flower charcoal extract is used for the haemorrhoids wet tissue liquid to achieve the effects of stopping bleeding, cleaning and mildly easing pain; double natural extracts are compounded to replace preservatives, traditional single symptom relief is upgraded to symptom treatment, mucous membrane repair and barrier protection, disease deterioration and recurrence risks are reduced, and the composition is free of chemical preservatives, free of irritant surface activity and suitable for being used by people with hemorrhoid symptoms.

The invention relates to the fields of genetic engineering and microbial fermentation, and discloses a recombinant strain for highly producing terpenoids as well as a construction method and application of the recombinant strain. The recombinant strain is obtained by genetic engineering modification of an original strain, compared with the original strain, the recombinant strain enhances the synthetic route of terpenoids, and the activity of pyruvate kinase, pyruvate dehydrogenase complex, glucose-6-phosphate dehydrogenase and key enzymes for synthesis of terpenoids is enhanced by using a CRISPR activation system; wherein the sgRNA expression promoters of the pyruvate kinase and the pyruvate dehydrogenase complex are respectively oleic acid induction type promoters, and the sgRNA expression promoters of the glucose-6-phosphate dehydrogenase and the terpene compound synthesis key enzyme are respectively copper ion induction type promoters. The recombinant strain can dynamically regulate and control an editing system of the terpenoids, precisely regulate and control the synthetic pathway flux of the terpenoids, and effectively improve the yield of the terpenoids (such as sclareol and bisabolol).

The invention discloses an NMN and bisabolol supramolecule as well as a preparation method and application of the NMN and bisabolol supramolecule. The method comprises the following steps: mixing NMN, choline chloride and glucosamine to form a transparent homogeneous liquid under the protection of nitrogen; and adding (-) alpha-bisabolol into the transparent homogeneous liquid, stirring and mixing, and carrying out vacuum degassing treatment to obtain the NMN and (-) alpha-bisabolol supramolecules. The obtained supramolecule solves the problem that the NMN and the (-) alpha-bisabolol are immiscible with each other, and meanwhile, the permeation resistance is reduced, and the transdermal absorption is promoted, so that the NMN and the (-) alpha-bisabolol cooperate with the skin to resist light aging. The invention further provides a method for preparing the supramolecules into the lipidosome through a lipidosome wrapping technology, the supramolecules achieve supramolecular smearing type skin care by means of the lipidosome wrapping technology, operation is easy and convenient, and the effect is fast. The method is suitable for preparing the skin anti-photoaging preparation.

The invention discloses a biomolecular film composition, a skin external preparation as well as a preparation method and application of the biomolecular film composition and the skin external preparation. The composition comprises the following components: 5%-30% of bisabolol; 2%-20% of oryzanol; 0-60% of grease; 0.3%-6% of ethyl cellulose and / or 5%-40% of a rape / tung oil copolymer; 0.5% to 8% of C20-40 acid; 0.1%-1% of a neutralizer; 0.025% to 0.225% of silk fibroin; 0.05% to 0.45% of glucomannan; and 0.1%-1.6% of a preservative. Water-soluble active molecules and oil-soluble active molecules are combined together through hydrophobic chains and hydrophilic chains in fibroin, the composition is prepared through high-pressure homogenization, and the composition has the effects of oxidation resistance, UV damage repair, UV light protection and inflammation resistance and can be adsorbed on the skin surface to form a film; the composition can be used together with a sun-screening agent, so that the sun-screening efficiency and stability of the sun-screening agent are improved, and relatively good water-resistant and sweat-resistant performance is provided.

The invention discloses a recombinant bacterium capable of increasing the yield of alpha-bisabolol as well as a preparation method and application of the recombinant bacterium, and belongs to the technical field of microorganisms. The invention aims to improve the yield of alpha-bisabolol and enhance the tolerance of a host to an organic solvent. The invention provides a recombinant bacterium for improving the yield of alpha-bisabolol. Escherichia coli is used as a starting strain; the method comprises the following steps of: overexpressing an acetyl CoA acyltransferase / HMG-CoA reductase mvaE gene, an HMG-CoA synthetase mvaS gene, a 2-methyl citrate dehydratase prpD gene, a mevalonate kinase ERG12 gene, a mevalonate 5-phosphate kinase ERG8 gene, a mevalonate 5-diphosphate decarboxylase ERG19 gene and an isopentenyl diphosphate isomerase idi gene, so as to obtain a recombinant vector; the gene is obtained from an alpha-bisabolol synthase gene of artichoke, a farnesyl diphosphate synthase ispA gene and an alpha-bisabolol synthase CcBOS gene of artichoke. The industrial process of synthesizing alpha-bisabolol by a biological method is promoted.

The invention discloses a traditional Chinese medicine combination effective part capable of improving diabetic peripheral neuropathy. The traditional Chinese medicine combination effective part is prepared from a volatile oil effective part, a water-soluble effective part and an alcohol-soluble effective part, the effective part of the volatile oil comprises alpha-ocimene, alpha-santalene, bisabolol, beta-bisabolol and nerolidol; the water-soluble effective part comprises salvianolic acid A, salvianolic acid B and tanshinol; the alcohol-soluble effective part is prepared from Z-ligustilide, alpha-masticinic acid, beta-masticinic acid, tanshinone IIA, and 2-methoxy-5-acetyl-furangermacane-1 (10)-ene-6-ketone, and the alcohol-soluble effective part is prepared from the following raw materials in parts by weight: 2-methoxy-5-acetyl-furangermacane-1 (10)-ene-6-ketone. The traditional Chinese medicine composition effective part provided by the invention can regulate blood sugar, improve the conduction speed of sciatic nerves, repair damaged tissues, inhibit oxidative stress reaction, resist inflammation and relieve pain, so that the diabetic peripheral neuropathy is improved, the curative effect is reliable, the safety is good, the adverse reaction is low, and the traditional Chinese medicine composition effective part can be used for preparing a medicinal preparation for improving the diabetic peripheral neuropathy.

The invention discloses supramolecular liquid crystal cream and a preparation method thereof, and relates to the technical field of cosmetic preparation. Comprising 0.3%-2% of supramolecular 10-hydroxydecanoic acid-alpha-bisabolol, 1.5%-5% of an emulsifier, 0.5%-3% of behenyl alcohol, 6.8%-23% of an emollient, 1.5%-6% of an emulsion stabilizer, 0.95%-2.85% of a thickener, 5%-14% of a humectant, 0.6%-1.8% of a preservative and a proper amount of water. Wherein the emulsion stabilizer comprises cetostearyl alcohol, and the mass ratio of the cetostearyl alcohol to the behenyl alcohol is (0.5-2): (0.5-3); the thickening agent comprises at least one of xanthan gum, microcrystalline cellulose / cellulose gum and bentonite. The specific thickening agent and the long-chain fatty alcohol emulsion stabilizer are added into the supramolecular system, so that ordered arrangement of liquid crystals in the supramolecular system is remarkably promoted, the mechanical strength of the lamellar liquid crystals is improved, and the stability of the supramolecular liquid crystal system is further improved.

The invention discloses a mild antibacterial anti-dandruff composition and a preparation method thereof. The composition comprises an acrylate copolymer, maltooligosaccharide and bisabolol, the mass ratio of the acrylate copolymer to the maltooligosaccharide to the bisabolol is (0.01 to 0.3) to (0.1 to 0.8) to (0.05 to 0.5); the preparation method comprises the following steps: sequentially adding the acrylate copolymer, the maltooligosaccharide and the bisabolol into water according to the mass ratio, and uniformly stirring until the materials are dissolved. The acrylate copolymer, the maltooligosaccharide and the bisabolol are blended in proportion, the maltooligosaccharide becomes a carbon source of microorganisms, malassezia is efficiently inhibited, staphylococcus epidermidis is not excessively inhibited, and meanwhile, the skin mildness and moisture retention are achieved; the bisabolol is used as a plasticizer, so that the composition of the acrylate copolymer and the maltooligosaccharide forms a uniform and tough film, the effect on malassezia and staphylococcus epidermidis is enhanced, and the anti-dandruff effect is improved.

Retinol-based composition. The present invention relates to a composition, particularly a cosmetic one, especially for makeup and / or the treatment of keratinous materials, comprising at least one retinoid, in particular retinol; bisabolol; 4-t-butylcyclohexanol; niacinamide; and D-panthenol. Figure for the abstract: None

The invention relates to the technical field of biology, and particularly discloses pichia pastoris as well as a construction method and application thereof. According to the pichia pastoris disclosed by the invention, beta-glucan is knocked out to synthesize a related gene gas1. By deleting the beta-glucan coding gene gas1 gene of the pichia pastoris cell wall, the cell size is reduced, the transmission distance from the cell surface to the cell nucleus is reduced, oxygen transmission and product secretion during high-density culture are improved, and the fermentation production efficiency is improved. In addition, the pichia pastoris constructed by the invention enhances the synthesis of the intracellular product bisabolol, and also can enhance the secretion ability of the intracellular product bisabolol. By reducing the cell size, reducing the carbon flow flowing to the cell wall polysaccharide synthesis and increasing the carbon source flowing to the target product synthesis, the application has great significance in industrial production.

The application provides a method for separating and purifying bisabolol from fermented residue of bisabolol, which comprises the following steps: taking the fermented residue of bisabolol, stirring with an organic solvent, filtering, taking the filtrate to decolorize, and distilling the decolorized liquid to obtain the bisabolol. The preparation method can successfully obtain high-purity bisabolol, and has the advantages of simple operation, low cost and low solvent toxicity.

The present invention discloses a fruit acid composition, a preparation method and an application thereof, belonging to the technical field of skin care products; the fruit acid composition provided by the present invention comprises a compound fruit acid, a compound soothing agent, betaine and D-panthenol; the compound fruit acid comprises lactic acid, glycolic acid, citric acid and lactobionic acid; the compound soothing agent comprises bisabolol and ginger root extract; by selecting appropriate fruit acids for compounding to form a compound fruit acid, and at the same time combining a compound soothing agent, betaine and D-panthenol, the obtained fruit acid composition can gently and non-irritatingly remove the cutin layer, whiten the skin and has excellent moisturizing effect on the skin. Further, when it is applied to the preparation of body wash, the obtained fruit acid body wash has excellent comprehensive performance.

The invention discloses an anti-allergy face cream containing a beta-sitosterol nano-composite and a preparation method of the anti-allergy face cream, and belongs to the technical field of cosmetics. Comprising the following components in percentage by mass: 3%-10% of a purified astragalus membranacus extract-beta-sitosterol nano complex, 1.65%-4.2% of a lipid complex, 0.5%-1% of bisabolol, 2%-4% of a natural emulsifier, 0.2% of a pH regulator, 6%-10% of grease and the balance of deionized water. The lipid complex comprises ceramide NP and cholesterol. The nano-complex is of a core-shell structure, the stability of beta-sitosterol can be improved, pH response type slow release of beta-sitosterol is achieved, systematic repair of sensitive skin can be achieved by regulating and controlling the inflammation-nerve dual-channel activity and optimizing the transdermal delivery mechanism, a dual-phase delivery system of the lipid complex and the nano-complex has a good application prospect, and the application prospect is wide. A compact physical repair barrier is formed, and a compact layered membrane structure is reconstructed to reduce trans-epidermal moisture loss.

The invention relates to the field of scalp water, in particular to scalp water with moisturizing, soothing and tightening effects as well as a preparation method and application of the scalp water. According to the scalp lotion, the active ingredients such as the perigord truffle extract, the mistletoe extract, the artemisia capillaris extract and the denseflower rodendranthus herb extract are selected, and the raw materials such as the humectant, the tripeptide-1, the witch hazel extract, the dipotassium glycyrrhizinate and the bisabolol with the moisturizing, relieving and tightening effects are selected, so that the scalp lotion has the moisturizing, relieving and tightening properties; meanwhile, selection of the raw materials is optimized, the process and matching of the extracts are improved, and the performance of tightening the scalp, relieving the scalp and the like is further improved.

The present application provides a kind of microalgae source glycerol glucoside preparation and its preparation method and application, belong to medical technical field.The crude extract solution is obtained by low-osmotic extraction liquid extraction to salt stress algal mud, impurity is removed by filtration, and phycocyanin concentrated solution and glycerol glucoside containing permeate are obtained by membrane filtration separation, glycerol glucoside containing permeate is concentrated, bleaching and desalting, drying, and microalgae source glycerol glucoside is prepared, is mixed uniformly with gypenoside and bisabolol, and the mixture is prepared, after being embedded with oleic acid modified cholesterol and phospholipid to prepare modified liposome, mixed with chitosan solution and reacted, centrifuged, and the supernatant is discarded, and the solid is washed and dried to prepare microalgae source glycerol glucoside preparation.The present application realizes the technical effects of microalgae resource green low-carbon high-value utilization, product efficient purification, multi-target point synergistic anti-inflammatory and high transdermal absorption retention, and provides a kind of safe and effective, long-term use natural source new choice for treating atopic dermatitis externally.

A heatable aerosol-generating article is provided, including: an aerosol-generating substrate, including a homogenised chamomile material, the homogenised chamomile material including at least 2.5 percent by weight of chamomile particles on a dry weight basis, an aerosol former, and a binder, at least 20 micrograms of bisabolol oxide A per gram of the aerosol-generating substrate, on a dry weight basis, at least 100 micrograms of tonghaosu isomers per gram of the aerosol-generating substrate, on a dry weight basis, and at least 15 micrograms of alpha-bisabolol per gram of the aerosol-generating substrate, on a dry weight basis; and at least one hollow tube immediately downstream of the aerosol-generating substrate. An aerosol-generating system, including an aerosol-generating device including a heating element, and a heatable aerosol-generating article, is also provided.

The invention relates to the technical field of skin care products, and discloses a skin soothing and repairing agent based on a hydroxyapatite microsphere composite material and a preparation method thereof, the skin soothing and repairing agent comprises the following raw materials by weight: 0.75-1.95 parts of tetrahydromethylpyrimidine carboxylic acid; 0.25 to 0.75 part of bisabolol; 1 to 2.3 parts of nicotinamide; 5 to 15 parts of hydroxyapatite microspheres; the repairing agent is efficiently loaded and slowly released, the porous structure of the hydroxyapatite (HAP) microspheres can efficiently adsorb relieving active matter, long-acting slow release is achieved through physical adsorption, and instantaneous high-concentration stimulation is avoided.

This invention discloses the application of α-bisabolol in the preparation of a quorum sensing quencher for Serratia liquefaction. It belongs to the field of pharmaceutical technology. The purpose of this invention is to provide an application in the preparation of a quencher for inhibiting the quorum sensing system of Serratia liquefaction, thereby reducing the toxicity of pathogenic bacteria without inhibiting their growth. This invention provides an application of bisabolol in the preparation of a quencher for inhibiting the quorum sensing system of Serratia liquefaction. It offers a novel solution for developing efficient and safe food preservatives.

The invention relates to an antiviral composition containing dextran and alpha-bisabolol, the weight ratio of dextran to alpha-bisabolol in the composition is (20: 1)-(1: 20), and the composition can be prepared into dosage forms such as soluble concentrate, suspending agent, emulsion in water and microemulsion. The composition is used for preventing and treating tobacco mosaic virus diseases, rice stripe diseases and vegetable and fruit virus diseases, is reasonable in components, has the effects of resisting viruses and improving the autoimmunity of crops, is good in antiviral effect, reduces the medication frequency and is low in medication cost, and the activity and the antiviral effect of the composition are not simple superposition of the activities of all the components but have a remarkable synergistic effect; and the composition has good safety to crops, and meets the safety requirements of pesticide preparations. The bactericidal composition has a good control effect on tobacco mosaic virus, rice stripe disease and virus diseases of vegetables, melons and fruits.

The application relates to the technical field of enzyme engineering, in particular to a (-)-alpha-bisabolol synthase mutant and application thereof. On the basis of a wild-type (-)-alpha-bisabolol synthase (SEQ ID No: 1), three types of (-)-alpha-bisabolol synthase mutants are constructed through substitution, deletion and addition mutation modes, and the (-)-alpha-bisabolol synthase activity of homologous mutants with different consistency obtained through the above different mutation modes is investigated, and the yield ratio relative to the wild type when used for fermentative production of (-)-alpha-bisabolol is investigated. It is proved that the above mutants all achieve the same or higher (-)-alpha-bisabolol yield as the wild-type (-)-alpha-bisabolol synthase. It is proved that the above mutation modes and the obtained mutants and the recombinant cells for biosynthesizing the mutants can be used for batch production and popularization of (-)-alpha-bisabolol, thereby helping the development of many downstream industries such as beauty and medicine.

This application relates to the field of biotechnology, specifically disclosing a *Pichia pastoris* yeast, its construction method, and its applications. This application involves knocking out the *gas1* gene, which is related to β-glucan synthesis, in *Pichia pastoris*. By deleting the *gas1* gene, which encodes β-glucan in the cell wall of *Pichia pastoris*, this application reduces cell size, decreases the transfer distance from the cell surface to the nucleus, improves oxygen transfer and product secretion during high-density culture, and enhances fermentation efficiency. Furthermore, the *Pichia pastoris* yeast constructed using this application enhances the synthesis of the intracellular product bisabolol and also enhances its secretion capacity. This application, by reducing cell size and decreasing the carbon flow to cell wall polysaccharide synthesis while increasing the carbon source flow to target product synthesis, has significant implications for industrial production.

The invention provides a high-concentration hydrogen peroxide emulsion for treating senile plaques and application thereof, and in the high-concentration hydrogen peroxide emulsion, hydrogen peroxide is used as an active component, can oxidize and decompose melanin in skin, and has a freckle removing effect; the hydrogenated polydecene is used as an emollient, so that the skin can be moistened and the texture of the skin is improved; hydrogenated castor oil (PEG-40) is used as an emulsifier, so that an emulsion system is stable; the bisabolol has anti-inflammatory and soothing effects, and can relieve the irritation of hydrogen peroxide to the skin; citric acid can adjust the pH value of the emulsion, so that the emulsion is more suitable for the physiological environment of skin; sodium hyaluronate has a moisturizing effect and can enhance the barrier function of skin. All the components have a synergistic effect, so that the emulsion has a good senile plaque treatment effect, and meanwhile, irritation to skin is reduced.

The invention relates to the technical field of cosmetics, in particular to a blue copper peptide-containing cosmetic as well as a preparation method and application thereof. Specifically, the transdermal composition containing the blue copper peptide comprises an active component tripeptide-1 copper and a transdermal synergistic component composed of methyl glucitol polyether-20 and hydrogenated lecithin according to the mass ratio of (5-15): 1, and the transdermal absorption rate and the storage stability of the blue copper peptide can be synergistically improved by the system; and / or the blue copper peptide synergistic composition comprises tripeptide-1 copper and a second active component composed of glycyrrhetinic acid and bisabolol, the mass ratio of the tripeptide-1 copper to the second active component is 1: (0.5-5), and the composition can generate a synergistic anti-inflammatory repair effect. According to the cosmetic disclosed by the invention, the technical bottlenecks that the blue copper peptide is poor in stability and difficult in transdermal penetration in cosmetics and cannot fully exert the effect in an inflammatory environment are effectively solved through independent or combined application of the composition.