54 results about "Palmitoyl tetrapeptide" patented technology

The invention discloses collagen polypeptide firming and anti-wrinkle freeze-dried powder, and relates to the technical field of cosmetics. The invention relates to a biological preservative which is prepared from water, butanediol, a bacillus / soybean fermentation product extract, soluble collagen, acetyl hexapeptide-8, panthenol, 1, 2, 4-trimethyl-1, 3-pentanediol and a proper amount of water. The cosmetic is prepared from 1, 2-hexanediol, tetrahydromethylpyrimidine carboxylic acid, hydroxypropyl tetrahydropyrantriol, tremella polysaccharide, saccharide isomeride, a bifidus yeast fermentation product lysate, sodium hyaluronate, DNA sodium, a radix gentianae extract, mannitol, palmitoyl tripeptide-1, palmitoyl tetrapeptide-7, oligopeptide-1, decapeptide-4, oligopeptide-3, hydrolyzed royal jelly protein, folic acid and disodium hydrogen phosphate. The additive is composed of sodium dihydrogen phosphate, citric acid and sodium citrate. The mask can provide rich nutrients for skin, deeply care the skin, moisturize and relieve the skin, tighten the skin, resist wrinkles and make the skin moisturized, glossy, elastic and tight, and is high in use safety and wide in application prospect.

The invention provides a hair care composition with oil control, hair loss prevention and repair effects and a preparation method of the hair care composition, and belongs to the technical field of hair care. The hair care composition comprises functional peptides such as myristoyl pentapeptide-4, palmitoyl tripeptide-1, acetyl tetrapeptide-3, hexapeptide-3, acetyl hexapeptide-8, palmitoyl tetrapeptide-7 and the like which are synergistically combined according to a specific proportion, and glycerin, water and a penetration enhancer are supplemented to form a basic system. By optimizing peptide structure modification, adding proportion and the steps of pH control, ultrasonic treatment and collaborative assembly in the preparation process, multi-path collaborative regulation and control of hair follicle activation, scalp inflammation inhibition and keratin synthesis enhancement are realized.

The invention relates to the technical field of skin care products, in particular to an anti-inflammatory repairing skin care compound and a preparation method thereof. The anti-inflammatory repairing skin care compound is prepared from the following components in percentage by mass: 10 to 15 percent of ganoderma lucidum extract, 5 to 10 percent of ginseng extract, 2 to 3 percent of radix angelicae powder, 3 to 5 percent of aloe vera gel, 5 to 8 percent of 4D hyaluronic acid, 8 to 12 percent of glycerol, 0.2 to 0.5 percent of p-hydroxyacetophenone, 2 to 3 percent of palmitoyl tetrapeptide-7, 0.5 to 1.2 percent of allantoin, 0.5 to 1 percent of bisabolol, 2 to 4 percent of asiaticoside and 3 to 5 percent of functional additive, 1-2% of an antioxidant, 1-2% of a thickening agent, 0.5-1% of an emulsifier, 0.2-0.5% of a chelating agent and the balance of deionized water; the anti-inflammatory repair skin care compound prepared by the invention not only has excellent anti-inflammatory soothing and moisturizing effects, but also has good repair and anti-oxidation effects on the skin, so that the skin aging speed is delayed to a certain extent, and the product quality is effectively ensured.

The invention discloses a long-acting moisturizing, tightening and anti-wrinkle composition as well as a preparation method and application thereof, and belongs to the technical field of cosmetics. The long-acting moisturizing, firming and anti-wrinkle composition is prepared from the following components: ginseng seed oil, hydrolyzed ginsenoside, collagen, acetyl hexapeptide-8, palmitoyl tripeptide-1, palmitoyl tetrapeptide-7, hydrolyzed sodium hyaluronate, a bifidus yeast fermentation product lysate, sodium mannose phosphate, an amaranth root extract and hexapeptide-9. Through the synergistic effect of all the components, the composition has good long-acting moisturizing, tightening and anti-wrinkle effects.

This invention belongs to the technical field of daily-use shampoo and hair care raw materials, specifically relating to a composition with hair-darkening effects and its application. The composition with hair-darkening effects provided by this invention is formulated from a compound of Platycladus orientalis leaf extract, Polygonum multiflorum extract, Eclipta prostrata leaf extract, Gynostemma pentaphyllum extract, palmitoyl tetrapeptide-10, L-arginine, and decapeptide-4. By adjusting the types and amounts of each component, the interaction between the components is improved, thereby increasing the relative activity of tyrosinase and the relative content of melanin, indicating that the components have a synergistic effect and excellent hair-darkening efficacy. The hair-darkening composition obtained by this invention is applied to the preparation of shampoo, which exhibits excellent hair-darkening effects and high safety, and has broad market application value in the field of hair-darkening or hair-protecting products.

The application discloses a composition with soothing anti-inflammatory anti-wrinkle firming efficacy and a preparation method thereof, and the composition comprises a TRPV1 inhibitor, an extract of Glycyrrhiza inflata Bat., palmitoyl tripeptide-1 and palmitoyl tetrapeptide-7. The four raw materials are compounded to have a synergistic effect, reduce the release of pro-inflammatory mediators and inhibit the high reactivity of nerve fibers to achieve soothing anti-inflammatory and anti-irritation; promote the generation of self collagen and sodium hyaluronate, reduce the oxidative stress response to achieve the anti-wrinkle firming efficacy and delay skin aging. The composition has comprehensive effects in soothing, anti-inflammatory, anti-irritation, anti-oxidation, anti-wrinkle and firming, reduces the generation of inflammation and delays skin aging, relieves the burning and stinging sensation of the skin at the same time, and meets the requirements of safety and high efficiency pursued by sensitive skin groups.

The present application relates to a kind of for sensitive skin improves mood stress skin aging composition preparation and application, belong to cosmetic technical field.The raw material of the composition for sensitive skin improves mood stress skin aging provided in the present application includes mulberry root extract, figwort flower extract, with distance stone branch algae extract, palmitoyl tetrapeptide-7, wherein with distance stone branch algae extract is prepared by bidirectional liquid fermentation method, four ingredients scientific compound, form " source control cortisol-skin structure repair " complete path, through target point clear, ring interlocking synergies, it is realized to sensitive skin mood stress skin aging Systematic improvement, provides a kind of mild, efficient and mechanism clear solution for sensitive skin anti-aging.

The invention discloses a composition for removing acne marks and inhibiting acne scar formation as well as a preparation method and application thereof, and relates to the technical field of cosmetics. The invention provides a composition for removing acne marks and inhibiting acne scar formation. The composition is prepared from the following components in parts by weight: 0.01 to 4 parts of white willow bark extract, 0.01 to 1 part of tephrosia chinensis seed extract and 0.01 to 3 parts of oligopeptide, the oligopeptides comprise an oligopeptide A and an oligopeptide B; the oligopeptide A is tripeptide-1 copper, and the oligopeptide B comprises at least one of palmitoyl tetrapeptide-7, palmitoyl pentapeptide-4, acetyl hexapeptide-8 and decapeptide-4. The composition prepared from the white willow bark extract, the tephrosia glauca seed extract and the oligopeptide synergistically plays a role in three stages of post-acne repair, and the prepared composition has the effects of removing acne marks and inhibiting acne scar formation.

The invention relates to the technical field of cosmetics, and particularly discloses an anti-wrinkle moisturizing brightening emulsion and a preparation method thereof. The anti-wrinkle moisturizing and brightening emulsion is prepared from the following raw materials in parts by weight: 78.594955 to 86.62996 parts of a solvent, 5.5 to 6.0 parts of a moisturizing agent A, 0.01 to 0.5 part of a moisturizing agent B, 0.1 to 3 parts of an emulsifying agent, 5.0 to 6.0 parts of an emollient, 1.5 to 2.5 parts of a skin conditioning agent A, 0.4 to 0.5 part of a skin conditioning agent B, 0.2 to 0.25 part of a skin conditioning agent C, 0.1 to 1 part of an antioxidant A, 0.05 to 0.055 part of an antioxidant B, 0.5 to 0.6 part of a thickening agent, 0.01 to 1 part of an anti-wrinkle agent and 0.000040 to 0.000045 part of arginine / lysine polypeptide, the anti-wrinkle agent is a mixture prepared from glycerol, water, sodium lactate, xanthan gum, palmitoyl tripeptide-1 and palmitoyl tetrapeptide-7. The emulsion provided by the invention has good anti-wrinkle and brightening effects.

The invention belongs to the technical field of biological medicine, and relates to a polypeptide composition as well as a preparation method and application thereof. According to the polypeptide composition, sodium carboxymethyl cellulose and xanthan gum are adopted as raw materials, pH-sensitive hydrogel capable of being rapidly cured at a wound is prepared, the hydrogel wraps polypeptide active ingredients and can be rapidly cured to form a layer of hydrogel film after being smeared on the affected part, the hydrogel film firmly covers the skin of the affected part, the environment of the affected part is kept stable and moist, and the wound healing effect is good. Necrotic tissues are softened, scabbing is reduced, active polypeptide components are continuously released, the action time is prolonged, and the repair period is shortened. The polypeptide component in the composition is compounded by arginine / lysine polypeptide, hexapeptide-11, palmitoyl tetrapeptide-7 and palmitoyl tripeptide-1, the four polypeptides construct an anti-inflammatory, repair-promoting and anti-scar complete-cycle repair system through multi-target and multi-stage synergy, and the composition is suitable for various skin wound scenes.

The invention discloses a composite multi-oligopeptide composition for skin repair and an application of the composite multi-oligopeptide composition. The multi-oligopeptide composition comprises the following components in parts by weight: 1 to 5 parts of acetyl hexapeptide-8, 0.1 to 1.5 parts of acetyl tetrapeptide-3, 1 to 20 parts of acetyl tetrapeptide-9, 0.1 to 1.5 parts of acetyl tetrapeptide-11, 10 to 190 parts of carnosine, 10 to 100 parts of decarboxylated carnosine hydrochloride, 10 to 120 parts of tripeptide-1, 1 to 50 parts of tetrapeptide-4, 1 to 20 parts of hexapeptide-9, 1 to 10 parts of palmitoyl pentapeptide-4, 1 to 5 parts of palmitoyl tetrapeptide-7, 1 to 10 parts of palmitoyl tripeptide-1, 1 to 35 parts of palmitoyl tripeptide-8, 0.1 to 2.5 parts of oligopeptide-1, 0.1 to 0.5 part of oligopeptide-2 and 0.1 part of carnosine. And 1 part of oligopeptide-5. The multi-oligopeptide composition has excellent anti-wrinkle and anti-aging effects, has the effects of promoting tissue repair and wound healing, strengthening skin barrier and resisting inflammation and relieving, is applied to skin medicine and skin beauty, and has the effects of promoting regeneration and remodeling of an extracellular matrix (ECM), regulating inflammation, blocking inflammatory aging and strengthening a dermis-epidermis joint (DEJ).

The application discloses a polypeptide-wrapped anti-wrinkle composition containing camellia sinensis leaf extract and application thereof, which comprises component A, component B and component C; the component A comprises palmitoyl tripeptide-5, palmitoyl tetrapeptide-7, polyol A and caprylic / capric triglyceride; the component B comprises PPG-13-decyltetradecin polyether-24 and polyol B; and the component C comprises water and camellia sinensis leaf extract. The application firstly solves the solubility problem of palmitoyl peptides, and secondly solves the compatibility problem of camellia sinensis leaf extract and palmitoyl peptides by low-energy emulsification technology, so that a transparent flowing liquid is obtained, which is more stable, safer, more effective, more convenient to apply, can promote collagen production and inhibit the activity of elastase, and better achieves the effects of improving wrinkles and delaying aging.

The invention belongs to the field of small molecule peptides, and particularly relates to a skincare combined peptide and a preparation method thereof, and the combined peptide contains palmitoyl tripeptide-5, palmitoyl tetrapeptide-7 and a solvent component. The combined peptide obtained by the invention has excellent anti-aging and anti-wrinkle effects, is simple in components, safe and non-irritant, and has a very good application prospect.

The invention relates to the technical field of cosmetics, in particular to an oil-soluble polypeptide composition of a pure oil system as well as a preparation method and application of the oil-soluble polypeptide composition. The composition comprises the following components: palmitoyl tetrapeptide-7, palmitoyl tripeptide-1, dipeptide diaminobutyryl benzyl amide diacetate, acetyl hexapeptide-8, arginine / lysine polypeptide and grease. Through compounding of palmitoyl tetrapeptide-7, palmitoyl tripeptide-1, dipeptide diaminobutyrylbenzylamide diacetate, acetyl hexapeptide-8 and arginine / lysine polypeptide, the eye cream can balance the structure and function of the skin and special problems of eyes, and has the effects of resisting oxidation and relieving inflammation; the technical problems that an existing eye care product is single in effect, high in irritation and poor in stability are solved, and the purpose of comprehensively improving the periorbital skin is achieved.

COMPOSITION AND METHOD USING IT The present invention relates to a composition comprising: (i) at least one collagen; (ii) palmitoyl tripeptide-1; (iii) palmitoyl tetrapeptide-7; and (iv) palmitoyl tetrapeptide-10. The present invention also relates to a non-therapeutic method for the treatment of keratinous materials, comprising the application of said composition to the keratinous materials. Figure for the abstract: none

The invention provides a composition with whitening, tightening and dull yellow improving effects and a preparation method thereof, the composition comprises raw materials such as nicotinamide, tranexamic acid, glycyrrhiza glabra root extract, biological tightening peptide and the like, and auxiliary components such as grape seed extract, modified hyaluronic acid and the like can also be added. The biological tightening peptide is prepared from palmitoyl tripeptide-5, palmitoyl tetrapeptide-7 and acetyl hexapeptide-8 according to a specific ratio. The preparation method comprises the steps of water phase preparation, active component dispersion, bioactive component addition, homogeneous stabilization and the like. Experiments show that the composition can efficiently inhibit tyrosinase activity and melanin synthesis and promote generation of elastin and collagen, is high in oxidation resistance and good in transdermal absorption effect, can be used for preparing cosmetics and has a good application prospect.

The embodiment of the invention provides anti-hair-loss, plump and dense hair essence, and relates to the field of hair care essence. The essence is prepared from water, ethyl alcohol, butanediol, PPG-26-butanol polyether-26, PEG-40 hydrogenated castor oil, tetrahydromethylpyrimidine carboxylic acid, 1, 2-hexanediol, caprylyl glycol, a ginseng root extract, palmitoyl tetrapeptide-7, a cacumen biotae extract, 1, 2-hexanediol, 1, 3-pentanediol, 1, 3-pentanediol, 1, 3-pentanediol, 1, 3-pentanediol, 1, 3-pentanediol and the like. The preparation method comprises the following steps: adding 1, 3-propylene glycol, phenoxyethanol, p-hydroxyacetophenone, carbomer, triethanolamine, adenosine, hydrolyzed sodium hyaluronate, hydrolyzed collagen, hydrolyzed elastin, caramel color, a scutellaria baicalensis root extract, a ginger root extract, copper tripeptide-1, a chamomilla recutita flower extract, glycerin, polysorbate-20, lactic acid, ethylhexylglycerin, carnosine, acetyl hexapeptide-8, palmitoyl pentapeptide-4, 2, 4-trimethyl-1, 2, 3-trimethyl-1, 2, 3-trimethyl-1, 2, 3-trimethyl-1, 2, 3-trimethyl-1, 2, 3-trimethyl-1, 2, 3-trimethyl-1, 2, 3-trimethyl-1, 2, 3-trimethyl-1, 2, 3-trimethyl-1 The composition is prepared from the following raw materials: palmitoyl tripeptide-1, rosemary leaf extract, acetyl hexapeptide-8, arginine / lysine polypeptide, acetyl tetrapeptide-2 and acetyl tetrapeptide-5.

The present invention belongs to the technical field of daily-use chemicals, and discloses a ginsenoside-containing composition, which includes the following components in parts by weight: 0.001-0.05 parts of palmitoyl tetrapeptide-7, 0.001-0.05 parts of blue copper peptide, 0.1-5 parts of ectoin, and 0.05-5 parts of a ginsenoside composition. According to the present invention, excellent fast acting and consistently-increased hair growth, hair loss prevention and hair development effects are achieved through preferred compounding of the ginsenoside composition and multiple polypeptides, etc. Meanwhile, the present invention further provides use of the composition and a daily-use chemical using the composition.

The present application relates to the daily chemical technology field, especially to a composition with multiple anti-aging effects and application thereof.The composition comprises retinol, palmitoyl tripeptide-1, palmitoyl tetrapeptide-7, lactobacillus / soybean milk fermentation product filtrate and resveratrol.The present application is a composition with a mild triple anti-aging system for promoting collagen regeneration and a preparation method thereof, which contains retinol, palmitoyl tripeptide-1, palmitoyl tetrapeptide-7, lactobacillus / soybean milk fermentation product filtrate and resveratrol, has obvious effects on skin epidermis and dermis aging, up-regulates skin flora balance, enhances the water-locking ability of the stratum corneum, improves the penetration rate of active ingredients, and increases cell vitality on the epidermis;in the epidermis+dermis, it has antioxidant and anti-inflammatory properties, the components are mild and have good absorption effect, and there is no need to establish tolerance, so that the skin resistance is consolidated, and it is especially suitable for sensitive skin.

The invention discloses a polypeptide composition with functions of whitening and brightening skin, resisting inflammation, resisting light aging and repairing skin, and relates to the technical field of skin care products. The polypeptide composition is prepared from oligopeptide-1, dipeptide-15, hexapeptide-9, palmitoyl tripeptide-5, tripeptide-2, palmitoyl tetrapeptide-7 and carnosine. According to the composition, through the synergistic effect of multiple active peptides, the effects of whitening and brightening skin, resisting inflammation, resisting light aging and repairing skin are achieved through multiple ways and multiple aspects, the effects of improving wrinkles, repairing skin, brightening skin color and delaying senescence can be better achieved, and the composition can be widely applied to various types of cosmetics.

The present invention relates to a method for preparing a high-purity hydrogel polypeptide, belonging to the technical field of polypeptide preparation. Specifically, the method involves mixing a crude hydrogel polypeptide with a solvent and eluting and purifying the hydrogel polypeptide using an eluent in a column separation system to obtain the hydrogel polypeptide; the eluent is a low-water mobile phase consisting of methanol, acetic acid, and water, or acetonitrile, acetic acid, and water; the volume proportion of water in the low-water mobile phase is less than 45% and not equal to 0%. The volume ratio of methanol to acetic acid in the low-water mobile phase is 1:0.5-5. The hydrogel polypeptide includes Phe-Val-Gln-Trp-Leu-Ile-Ala-Gly or palmitoyl tetrapeptide-20.

Disclosed is a cosmetic composition comprising (a) oligopeptide selected from oligopeptide-1, palmitoyl oligopeptide-1, acetyl oligopeptide-1, myristoyl oligopeptide-1, or a combination thereof; (b) tetrapeptide selected from tetrapeptide-9, acetyl tetrapeptide-9, palmitoyl tetrapeptide-9, myristoyl tetrapeptide-9, or a combination thereof; and (c) hexapeptide selected from hexapeptide-11, acetyl hexapeptide-11, palmitoyl hexapeptide-11, myristoyl hexapeptide- 11, or a combination thereof.

The present application provides a composition containing a hyaluronic acid-glutamic acid grafted compound and palmitoyl tetrapeptide-7, wherein the mass ratio of the grafted compound to the palmitoyl tetrapeptide-7 is in the range of 1:5 to 5:1. The composition can significantly enhance the anti-inflammatory efficacy of a hyaluronic acid-glutamic acid graft with a high grafting degree, thereby achieving both long-lasting anti-inflammatory and effective anti-inflammatory effects.

The invention relates to a polypeptide hair nourishing composition with high stable activity and a preparation method thereof, and relates to the technical field of hair nourishing and caring, the polypeptide hair nourishing composition comprises 0.01%-0.5% of palmitoyl tetrapeptide-10, 0.005%-0.3% of myristoyl pentapeptide-4, 0.01%-0.2% of gastrodin, 1%-5% of hyaluronic acid liposome, 40%-55% of a solvent, 0.5%-3% of a penetration enhancer, 0.2%-4% of a composite antioxidant, 0.2%-6% of a stabilizer, 0.1%-1% of a preservative and a proper amount of deionized water. The composition disclosed by the invention has a liposome targeted delivery function, has hair follicle activation and scalp environment optimization functions, and is stable in components, good in activity and excellent in hair nourishing and caring effects.

The present invention relates to a composition, in particular a cosmetic composition, comprising, in a physiologically acceptable medium: (i) at least one extract of Grifola frondosa; (ii) at least one monosaccharide; (iii) at least one N-Palmitoyl-Gly-His-Lys tripeptide; and (iv) at least one N-Palmitoyl-Gly-Gln-Pro-Arg tetrapeptide of sequence SEQ ID NO: 1. It also relates to a non-therapeutic cosmetic process for caring for keratin materials, in particular the skin, comprising the topical application to these keratin materials of a composition according to the invention, or the use thereof for preventing and / or treating the signs of skin ageing.

The application relates to the technical field of eye care products, and particularly discloses an eye essence cream and a preparation method thereof. The eye essence cream comprises a moisturizing agent, an antioxidant, a penetration promoter, a viscosity regulator, an emulsifier, an emollient, a thickening agent, Coffea arabica seed oil, Baphia nitida bark extract, an anti-wrinkle composition, a Mei flower extract, a Pediococcus / Parsnip root ferment filtrate, an Adzuki bean seed extract, caprylyl glycol, acetyl hexapeptide-8, acetyl tetrapeptide-2, lactose, whey protein, lactic acid and the like. The anti-wrinkle composition is prepared by mixing acetyl hexapeptide-8, conotoxin, Hedychium spicatum extract, palmitoyl tripeptide-1 and palmitoyl tetrapeptide-7. The eye essence cream provided by the application has a comprehensive and efficient improvement effect on complex problems such as dry skin, fine lines, relaxation, dark circles and eye bags.

The invention discloses a composition with a function of delaying skin aging as well as a preparation method and application of the composition. The composition comprises the following components in parts by weight: 40-45 parts of a white poria extract, 10-40 parts of a ginseng extract, 5-8 parts of a lotus seed extract, 5-8 parts of radix angelicae powder, 5-8 parts of aloe vera gel, 12-16 parts of 4D hyaluronic acid, 15-20 parts of glycerol, 3-5 parts of palmitoyl tetrapeptide-7 and the balance of deionized water. Through compatibility of the white poria extract, the ginseng extract, the lotus seed extract, the radix angelicae powder, the aloe vera gel, the 4D hyaluronic acid, the glycerol, the palmitoyl tetrapeptide-7 and the deionized water, the composition with the skin aging delaying function is prepared, and the composition has an obvious skin aging delaying effect and has an excellent improvement effect on various skin problems; the white poria extract and the ginseng extract are compatible in proportion to generate a definite synergistic effect instead of a simple additive effect; the moisturizing cream can moisturize and brighten the skin color, improve the dull yellow skin, and realize the effect of delaying skin aging.

The invention relates to a washing and caring composition with dandruff removing, itching relieving and repairing effects and a preparation method of the washing and caring composition, and belongs to the technical field of daily chemicals. Aiming at dandruff formation and itching factors of scalp, the piroctone olamine salt, palmitoyl tetrapeptide-10, tetrapeptide-1 and speranskia herb extract are correspondingly compounded to play a role in removing dandruff and relieving itching, and the limitation of a single component is made up by compounding chemical components and plant extracts, so that more efficient and milder scalp care is realized. In addition, the dihydrooat acyl o-aminobenzoic acid, pyridoxine tripalmitate and quaternary ammonium salt-73 are combined for use, so that the shampoo also has an excellent synergistic repairing capability on scalp with symptoms such as acne, red and swollen, slight folliculitis and the like.

The invention discloses a remodeling active peptide and a preparation method thereof, and belongs to the technical field of active peptides. Comprising the following components in parts by weight: 2-4 parts of acetyl octapeptide-3, 2-3 parts of acetyl hexapeptide-8, 2-3 parts of snake venom-like peptide, 3-5 parts of palmitoyl tripeptide-1, 3-5 parts of palmitoyl tetrapeptide-7, 3-5 parts of palmitoyl hexapeptide-12, 1-2 parts of tripeptide-1, 5-10 parts of a traditional Chinese medicine extract composition, 2-3 parts of white honey, 2-3 parts of walnut kernel oil, 3-5 parts of a cubilose extract and 1-2 parts of vitamin E, 2-3 parts of hyaluronic acid, 1-2 parts of ceramide and the balance of rose water. According to the invention, the designed traditional Chinese medicine extract composition can synergistically enhance skin repair, metabolism and circulation functions based on compatibility, forms a comprehensive action network for tonifying middle-Jiao and Qi, activating blood and nourishing skin, harmonizing and removing turbidity and dredging meridians and collaterals, and complements with a molecular signal mechanism of active peptides, so that the skin is improved in a cell layer, a corium layer and a barrier layer.

The invention belongs to the field of new daily chemical materials, and discloses an anti-propionibacterium acnes composition, which comprises a radix sophorae flavescentis extract and colloidal sulfur, and the weight ratio of the radix sophorae flavescentis extract to the colloidal sulfur is (0.5-1): (5-10). Meanwhile, the invention also discloses an acne-removing composition, which is prepared from the radix sophorae flavescentis extract, colloidal sulfur and palmitoyl tetrapeptide-7, the weight ratio of the radix sophorae flavescentis extract to the palmitoyl tetrapeptide-7 to the colloidal sulfur is (0.5-1): (0.01-0.05): (5-10); according to the propionibacterium acnes resisting composition, the radix sophorae flavescentis extract and the colloidal sulfur are adopted as active ingredients, and the radix sophorae flavescentis extract has a certain antibacterial ability and can effectively promote the antibacterial performance of the colloidal sulfur to play. The acne-removing composition can effectively control acnes, remove acnes and eliminate pockmarks. Meanwhile, the invention also provides application of the composition.