589 results about "Caprylic acid" patented technology

The invention discloses a scalp essence capable of controlling oil and removing dandruff and a preparation method thereof, and provides the scalp essence capable of controlling oil and removing dandruff. The formula consists of the following raw materials: water, saccharomycetes / rice fermentation product filtrate, butanediol, phenoxyethanol, caprylic acid / capric triglyceride, galactose yeast-like bacterium fermentation product filtrate, allantoin, a saccharomycetes / zinc fermentation product, nicotinamide, arginine, polysorbate-20, hydrogenated lecithin, acrylic acid (ester) / C10-30 and an alkanol acrylate cross-linked polymer. Hydrolyzed sodium hyaluronate and trace components. According to the oil-controlling and dandruff-removing scalp essence disclosed by the invention, through the synergistic interaction among the raw materials, the effects of replenishing water, preserving moisture, controlling oil and removing dandruff are increased, the effects of relieving, recovering oil-water balance, recovering skin elasticity and delaying senescence are also achieved, the effects of preventing hair loss and nourishing hair are also achieved, and meanwhile, the oil-controlling and dandruff-removing scalp essence has the advantage of being stable in storage.

The invention discloses an alcohol dehydrogenase mutant and application of the alcohol dehydrogenase mutant in asymmetric synthesis of (S)-6-hydroxy-8-chloro ethyl caprylate with optical purity. The alcohol dehydrogenase or the mutant thereof provided by the invention has extremely high conversion rate and can effectively improve the optical purity of the product. Moreover, based on the mutant, low-cost, efficient and rapid production of single-configuration ethyl 6-hydroxy-8-chloro caprylate can be realized, a multi-configuration mixture is not generated, and the problems of tedious steps, pollution and the like caused by a conventional chemical synthesis method are also avoided.

The present invention provides: a fermented beer-like sparkling beverage having a real fermentation degree of 60% or less and a value of ([real extract (w / v%)]-[real final extract (w / v%)]) / [real extract (w / v%)] × 100 of 20% or less; the fermented beer-like sparkling beverage having a value of [original wort extract (w / v%)] × [malt ratio (w / w%)] of 1200 or less; and any one of the above-mentioned fermented beer-like sparkling beverages, in which the ratio (Es / HA) of the total concentration (mg / L) (HA) of ethyl acetate, isoamyl acetate, ethyl caproate, ethyl caprylate, and β-phenethyl acetate to the total concentration (mg / L) (Es) of isobutanol, isoamyl alcohol, and β-phenethyl alcohol in the beverage is 15% or less.

This invention discloses a method for preparing an air-based hydrophilic-oleophobic coating, comprising the following steps: a) adding a silane coupling agent to ethanol to obtain solution A; b) first adding perfluorooctanoic acid and sodium hydroxide to ethanol to obtain a sodium perfluorooctanoate ethanol solution, then adding at least two types of hydrophilic nanoparticles of the same particle size to the sodium perfluorooctanoate ethanol solution to obtain solution B; c) adding a fluorinated surfactant and at least two types of hydrophilic nanoparticles of the same particle size to ethanol to obtain solution C; d) first mixing solution B and solution C uniformly to obtain solution D, then slowly adding solution A dropwise to solution D to obtain suspension E; e) spraying suspension E onto the surface of a substrate and drying at 55-65°C for 1-3 hours to obtain an air-based hydrophilic-oleophobic coating. The preparation method of this invention is simple, and the resulting coating exhibits excellent hydrophilicity and oleophobicity, acid and alkali resistance, salt resistance, and oil stain resistance.

The invention relates to the technical field of polymer degradable materials, in particular to a biodegradable material as well as a preparation method and application thereof. The material takes modified polylactic acid as a main body, and an antioxidant, a plasticizer, a flame retardant and an inorganic filler are used as auxiliary materials in parts by weight. The method is characterized in that lactic acid and an epicatechin imidazole ammonium chloride polymer are polymerized under the catalysis of stannous octoate, and an epicatechin bioactive group is introduced into a polylactic acid main chain in a chemical bonding manner, so that the biodegradation rate, the mechanical property and the thermal stability of the material are remarkably improved. Bioactive substances and ionic groups in the material promote microbial degradation, and the material can be completely decomposed in a compost environment in a short time; meanwhile, the strength, the toughness and the high-temperature processability of the polylactic acid are effectively improved through molecular-level enhancement and an ionic cross-linking effect. The material can be widely applied to the fields of disposable tableware, food packaging films, degradable agricultural mulching films and the like.

The invention relates to the technical field of pharmaceutical preparations, in particular to a docetaxel oral self-microemulsion composition and a preparation process thereof. The docetaxel oral self-microemulsion composition is prepared from docetaxel, an oil phase, a surfactant, a cosurfactant, a stabilizer and an antioxidant, the oil phase is caprylic / capric acid mono / diglyceride, medium chain triglyceride, caprylic acid propylene glycol ester or lauric acid propylene glycol ester. The docetaxel oral self-microemulsion composition provided by the invention has relatively high drug loading capacity, good physical and chemical stability and relatively high bioavailability, and is more suitable for clinical medication.

The invention belongs to the technical field of cosmetics, and particularly relates to a water-in-oil-in-water three-phase coated microbead as well as a preparation method and application thereof. The water-in-oil-in-water three-phase coated microbead is of a spherical structure and sequentially comprises an outer water phase, an inner oil phase and an inner water phase from outside to inside, the outer water phase comprises sodium alginate, agarose, cyclodextrin, glycerin and other components, the inner oil phase comprises caprylic / capric triglyceride, grape seed oil, olive squalane, tocopherol and other components, and the inner water phase comprises sodium alginate, agarose, cyclodextrin, glycerin and other components. And the inner water phase comprises ampelopsis grossedentata extract, astragalus membranacus root extract and other components. According to the invention, an easily oxidized and unstable active matter is fully and firmly protected by adopting a droplet microfluidic coating technology, so that the active matter is free from external stimulation, active ingredients with different effects play multiple roles, and the composition has good anti-inflammatory, soothing and oil-controlling effects and can be applied to the field of cosmetics.

An oral suspension pharmaceutical composition is disclosed for water soluble salts of arylalkanoic acid (NSAID) drugs such as ibuprofen and naproxen. When mixed with glyceryl esters such as glyceryl caprate / caprylate and water, the resulting combination forms a “liquid scaffold” structure that reliably enables the suspension of significant quantities of said arylalkanoic acid drugs. For example, suspensions containing 25% w / w arylalkanoic acid may be obtained using the aforementioned combination. Suspensions comprising further pharmaceutically active agents, in addition to said arylalkanoic acids, may also be prepared. Also disclosed is a binary blend of glyceryl caprate / caprylate and the sodium salt of ibuprofen and a ternary blend of glyceryl caprate / caprylate and the potassium salt of ibuprofen.

The invention relates to the technical field of industrial microorganisms, and particularly discloses a yeast strain and application thereof. The invention provides clavipora lusitaniae YJHT233, which is obtained through space mutation breeding, can tolerate 9% of alcohol, can tolerate an acid environment with the lowest pH value of 2.5, can tolerate a 12% high NaCl system, a 55% high glucose system and a 44 DEG C high temperature environment, and has excellent ester production capacity. The strain is used for brewing rice-flavor liquor or yellow wine, the total content of ester substances in the obtained product is greatly increased, the content of main volatile ester substances such as ethyl acetate, ethyl butyrate, isoamyl acetate, ethyl caprylate and ethyl lactate is remarkably increased, the whole flavor is coordinated and pleasant, and the fruit fragrance is rich and rich in layers.

The invention belongs to the technical field of cosmetics, and discloses micro-emulsion essence water containing ceramide and a preparation method of the micro-emulsion essence water. The micro-emulsion essence containing ceramide is prepared from the following components: an emulsifier, a humectant, polypeptide, small molecular grease and water, the emulsifying agent comprises polyglycerol-10 oleate, the emulsifying agent does not contain a PEG and / or PPG structure, the humectant comprises glycerol and ceramide, and the small molecule grease comprises at least one of tridecane, undecane, isononyl isononanoate, propyl heptyl octoate, coconut oil alcohol-octoate / caprate, dicapryl carbonate and dioctyl ether. The micro-emulsion essence water containing ceramide has excellent stability, low viscosity, refreshing texture which is common to water and fine skin feeling, and also has excellent moisturizing and tightening effects.

The invention belongs to the technical field of microbial fermentation, and particularly relates to a new enterobacter rorrhizae strain as well as a separation and screening method and application thereof. In order to enrich microbial resources for producing pyrazine substances through metabolism in the white spirit industry, an enterobacter rorrhizae strain is separated and screened from a mixture of yeast for making hard liquor and fermented grains, and the preservation number is CGMCC No.33262. The strain has good tolerance to pH, salt and alcohol, and can adapt to the growth environment in the white spirit production process; and various pyrazine substances represented by tetramethylpyrazine can be produced. Besides, the strain has strong adaptability to fermented grains, the yield of tetramethylpyrazine is high in a culture medium taking bran, wheat and five grains as the fermented grains, and meanwhile, various flavor substances such as ethyl acetate, ethyl hexanoate, ethyl caprylate, 2, 3-butanediol, guaiacol and 4-vinyl guaiacol can be produced. Therefore, the enterobacter rorrhizae disclosed by the invention can be widely used for brewing white spirit.

The invention belongs to the technical field of veterinary drug preparations, and particularly relates to a compound external ointment for treating parasites of dogs and cats and skin tinea and a preparation method, the compound external ointment comprises the following components by mass percent: 2%-12% of selamectin, 3%-20% of imidacloprid, 0.5%-2% of terbinafine hydrochloride, 2%-12% of dipropylene glycol monomethyl ether, 10%-50% of isopropanol, 9%-45% of polyethylene glycol 400 and the balance of water. The adhesive is prepared from, by weight, 9%-45% of polyethylene glycol 3350, 5%-15% of caprylic / capric polyethylene glycol glyceride, 1%-8% of oleyl alcohol, 0.5%-5% of dimeticone, 0.01%-0.1% of butylated hydroxytoluene and 1%-5% of cassava starch polymethylsesquioxane. The preparation method comprises the following steps: uniformly stirring the selamectin, the imidacloprid, the terbinafine hydrochloride and the mixed solvent, then mixing with the matrix (the polyethylene glycol 400 and the polyethylene glycol 3350 are heated and uniformly mixed in advance), the emulsifier and other components, and homogenizing. The compound selamectin ointment prepared by the invention can realize accurate administration at the edge of the auricle of an animal, and not only can ensure that the medicine is fully absorbed, but also can improve the compliance of animal administration; the composition not only can expel parasites in a broad spectrum, but also has broad-spectrum antifungal activity, and can prevent and treat a plurality of skin diseases of pets.

The invention discloses allicin oleogel as well as a preparation method and application thereof, and belongs to the technical field of medicines. The allicin oleogel is prepared from the following raw materials: allicin, an oil phase, a gelator and a surfactant, the gelator comprises beeswax and / or fruit wax; the surfactant comprises one or more of caprylic / capric polyethylene glycol glyceride, Tween 20 and polyglycerol fatty acid ester. The gel factor forms oil gel through crystal self-assembly, allicin is solidified and intercepted in the oil gel, the gel factor is optimized, and a surfactant is used in a matched manner, so that a release behavior similar to that of a mixed solution of free allicin and an oil phase can be obtained, and the transdermal release rate is improved. The allicin oil gel can effectively entrap allicin, cover the peculiar smell of the allicin and improve the stability of the allicin, and through abdominal transdermal administration, the medicine accumulation amount in subcutaneous adipose tissues is remarkably increased, and the treatment effect on obesity and complications thereof can be improved.

The invention discloses a method and a system for producing high-purity medium-chain fatty acid (MCFA) based on waste molasses two-stage regulation fermentation. Comprising the following steps: (1) diluting waste molasses, then adding a compound enzyme agent of pectinase, beta-glucanase and cellulase, and coupling microwave to assist treatment; (2) inoculating the pretreated waste molasses with a composite flora containing a clostridium kluyveri mutant strain and a Megasphaera elsdeni engineering bacterium, and carrying out a fermentation treatment on the waste molasses, wherein the composite flora contains the clostridium kluyveri mutant strain and the Megasphaera elsdeni engineering bacterium; (3) sequentially performing two-stage dynamic regulation and control fermentation on the waste molasses inoculated with the composite flora through a pH-stat control strategy to realize efficient conversion from butyric acid to hexanoic acid / octanoic acid; and (4) a hydrophobic hollow fiber membrane module is adopted to realize on-line removal of the product, and the inhibition effect of the product is relieved. According to the technology, the yield of the MCFA produced from the waste molasses reaches 0.45 g / g COD, the cost is reduced by 68% compared with that of a traditional substrate, and a new way is provided for recycling of sugar manufacturing waste.

The present invention relates to detergents and cleaning compositions that comprise a surfactant, an anti-redeposition agent, and an effective amount of 1,2-heptanediol and / or 2,3-heptanediol or a specific type of anti-redeposition boosting agent, such as alkanediols, glyceryl caprylate, 4-hydroxyacetophenone, ethyl hexyl glycerin or tropolone, and the use of said detergents and cleaning compositions for the preparation of a detergent and cleaning product for household, institutional and industrial application. Furthermore, the present invention relates to a method of treating a stained and / or soiled substrate, using the detergents and cleaning compositions according to the present invention. Additionally, the present invention relates to the use of 1,2-heptanediol and / or 2,3-heptanediol or of specific substances as defined herein for boosting the activity of an anti-redeposition agent in a detergent and cleaning composition and / or for improving cleaning performance of a detergent and cleaning composition. Moreover, the present invention relates to a method of boosting the activity of an anti-redeposition agent in a detergent and cleaning composition and / or of improving cleaning performance of a detergent and cleaning composition by adding an effective amount of 1,2-heptanediol and / or 2,3-heptanediol or of specific anti-redeposition agents, such as alkanediols, glyceryl caprylate, 4-hydroxyacetophenone, ethyl hexyl glycerin or tropolone to said detergent and cleaning composition. Finally, the present invention relates to the use of 1,2-heptanediol, 2,3-heptanediol or a mixture comprising 1,2-heptanediol and 2,3-heptanediol or at least one anti-redeposition boosting agent, such as alkanediols, glyceryl caprylate, 4-hydroxyacetophenone, ethyl hexyl glycerin or tropolone as anti-redeposition agent.

The present invention relates to a preparation method and application of a supramolecular aggregate surfactant, and belongs to the field of supramolecular coordination chemistry, surface modification engineering and hydrophobic coating technology. In the present invention, 4-hydroxypyridine-2,6-dicarboxylic acid and malonic acid prepare an adhesive ligand, and with the help of the coordination of the carboxyl structure and lanthanum ions on 4-hydroxypyridine-2,6-dicarboxylic acid and perfluorooctanoic acid, a supramolecular aggregate in a nano-aggregated state is obtained, which is self-assembled into a supramolecular aggregate surfactant. The active agent can solubilize fluoride and can also be applied in the field of hydrophobic coatings. The coating has the characteristics of imitating lotus leaf structure and hydrophobic wax, and has good hydrophobic properties.

The invention belongs to the technical field of synthetic ester, and particularly relates to a preparation method of fatty acid pentaerythritol ester base oil, which comprises the following steps: carrying out esterification reaction on pentaerythritol and fatty acid in the presence of a catalyst and a color retention agent, and carrying out post-treatment to obtain the fatty acid pentaerythritol ester base oil, the catalyst comprises at least one of stannous octoate, stannous oxalate, stannous oxide, tetrabutyl titanate, isopropyl titanate and sodium hydrogen sulfate; the color retention agent comprises at least one of sodium hypophosphite, hypophosphorous acid, activated carbon and sodium sulfite. The color retention agent sodium hypophosphite is matched with the specific catalyst such as stannous oxalate, so that the petroleum color number of the produced fatty acid pentaerythritol ester base oil is smaller, and meanwhile, the esterification reaction time is shorter.

The invention relates to the technical field of cosmetics, in particular to preparation and application of a cyclodextrin-coated azelaic acid oil-control skin-care product. Comprising the following steps: S1, adding deionized water into a mixer, adding a cyclodextrin-azelaic acid inclusion compound, nicotinamide and allantoin, mixing to obtain a water phase, mixing glycerol, caprylic / capric triglyceride, polydimethylsiloxane, polysorbate-80 and tocopheryl acetate to obtain an oil phase, slowly adding the oil phase into the water phase, and shearing and emulsifying to obtain a nanoemulsion; and S2, cooling the nano-emulsion, adding carbomer while stirring, continuously cooling to room temperature, sequentially adding phenoxyethanol, ferulic acid, menthol and essence, adjusting the pH value of the emulsion with triethanolamine, homogenizing, defoaming, disinfecting and filling. By adjusting the proportion of the components in the formula, the skin feeling of the product can be further optimized, so that the product is more comfortable and not greasy, and a lasting oil control effect is provided.

The invention relates to the field of cosmetics, and discloses ceramide liposome and application thereof.The ceramide liposome is prepared from, by mass, 1.5-3 parts of ceramide NP, 1-3 parts of octyldodecanol, 0.5-2 parts of caprylic / capric triglyceride, 11-18 parts of hydrogenated lecithin, 2-6 parts of sucrose stearate, 3-7 parts of polyglycerol-10 oleate and 25-35 parts of glycerinum, and the balance is water. 0.5-8 parts of 1, 2-pentanediol, and the balance of water. The ceramide liposome provided by the invention has good stability at least at 40 DEG C, is not easy to cause lactic acid pricking pain and allergy after being smeared on skin, and can be used for sensitive skin; the skin care product can reduce skin transdermal moisture loss, maintain skin cutin moisture, reduce skin heme content, improve skin gloss, relieve skin dryness, relieve skin redness and improve skin fineness, and has the effects of moisturizing, repairing and relieving.

The application discloses a soluble microneedle composition for transdermal delivery of polypeptides and application thereof. The soluble microneedle composition comprises a first composition and a second composition; wherein the first composition comprises the following components in mass percentage: 20-60% polypeptides, 0.5-20% capryol 98, 10-40% first biocompatible polymer material and 0.5-20% first surfactant; the second composition comprises the following components in mass percentage: 98-99.75% second biocompatible polymer material and 0.25-2% second surfactant. The microneedle composition is used in the microneedle, and the problems of low transdermal efficiency and poor stability of polypeptides are solved.

The invention relates to the technical field of repair compositions, and discloses a repair composition based on mussel mucin and application of the repair composition in skin barrier repair. The invention discloses a mussel mucoprotein-zinc composite microcapsule repair agent, which is prepared from the following components in parts by weight: mussel mucoprotein-zinc composite microcapsules, modified carboxymethyl chitosan, isolactone palmitate, a pH response type ceramide slow release system, dimeticone, cetostearyl alcohol, a calcium ion activating agent, an auxiliary repair factor, beheneth-25, caprylic / capric triglyceride, glyceryl monostearate, glyceryl distearate, pentanediol and citric acid. The preparation method comprises the following steps: adding ethanol, phenoxyethanol / ethylhexylglycerin, trehalose, beta-glucan and purified water; according to the whole technical scheme, through functional complementation and process optimization of all the components, synergistic interaction is achieved, the transpedermis water loss amount can be rapidly reduced, the water content of the skin cuticle is increased, the damaged skin barrier structure can be repaired from the source, and the resistance and stability of the skin are remarkably improved.

The invention discloses a strain of saccharomyces cerevisiae CPJ-02 with high acid resistance, high ethanol content and strong ester aroma generation and application of the saccharomyces cerevisiae CPJ-02, the strain of the saccharomyces cerevisiae CPJ-02 has been preserved in China Center for Type Culture Collection on June 27, 2024; the preservation number of the strain is CCTCC NO: M 20241388. The saccharomyces cerevisiae CPJ-02 strain is milky white to faint yellow after being cultured on a YPD solid plate for 48 hours, the surface is dry and matte, the texture is slightly rough, and the colonial morphology is round. The saccharomyces cerevisiae CPJ-02 strain has prominent high ethanol tolerance, and still has activity greater than or equal to 92% in a 12% ethanol environment; and the fermentation product is rich in aroma and high in ethyl caprylate and phenethyl alcohol content, more than or equal to 25 volatile substances are detected by GC-MS (gas chromatography-mass spectrometry), and the fermented product is rich in fruit fragrance and has ester flower fragrance. The saccharomyces cerevisiae CPJ-02 strain is suitable for production of high-concentration wines and directional production of low-concentration healthy fermented beverages, fermented foods and aroma compounds.

The invention belongs to the technical field of skin care products, and discloses a quick-acting red-removing repair product which comprises the following components: water, caprylic / capric triglyceride, glycerol, sorbitol, phosphatidylcholine, 1, 3-propylene glycol, xanthan gum, eicosapentaenoic acid, docosahexaenoic acid, phytosphingosine, centella asiatica extract and tocopheryl acetate. A turmeric rhizome extract and 1, 2-hexanediol. Through mutual cooperation of the turmeric root extract and the centella asiatica extract, by taking enhancement of skin immune regulation and skin barrier functions as an action mechanism, on one hand, skin inflammatory response can be inhibited, and inflammation, microorganisms and bacteria can be effectively resisted, and on the other hand, skin barrier reconstruction can be promoted, wound healing can be promoted, and an ECM matrix can be protected; in addition, the eicosapentaenoic acid, the docosahexaenoic acid, the turmeric root extract, the phytosphingosine and the centella asiatica extract are wrapped by the nano-microcapsule liposome, so that the activity of the product can be ensured.

The invention discloses soothing, repairing and moisturizing face cream as well as a preparation method and application thereof. The soothing, repairing and moisturizing face cream is prepared from the following components in percentage by mass: 2.2 to 5.8 percent of soothing agent, 2.13 to 6.75 percent of repairing agent, 16 to 33 percent of moisturizing agent, 0.5 to 1 percent of thickening agent, 5.5 to 17 percent of emulsifying agent, 1 to 2 percent of preservative and the balance of water, the soothing agent is prepared from an opuntia ficus-indica fruit extract, dipotassium glycyrrhizinate, bisabolol and meadowfoam seed oil; the repairing agent is prepared from cholesterol, ceramide NP, phytosphingosine, ceramide AP, tetraacetyl phytosphingosine and sodium hyaluronate. The repairing agent can repair skin barriers in a multi-level mode, the relieving agent can relieve skin sensitivity and redness, petrolatum, glycerin, caprylic / capric triglyceride and isononyl isononanoate form a protective layer outside the skin, and the action time of active ingredients is prolonged; secondly, by compounding different emulsifiers, the skin feeling problem in the use of the high petrolatum component is effectively solved, so that the excellent skin feeling and comfort of the face cream are maintained on the basis of the high petrolatum component.

The invention discloses an application of morchella enzymolysis polysaccharide in regulating lipid metabolism disorder. The morchella enzymolysis polysaccharide disclosed by the invention can be used for regulating lipid metabolism disorder, regulating intestinal flora and preventing liver injury, oxidative stress and inflammation. The morchella esculenta adopted by the invention is medicinal and edible morchella esculenta, is free of chemical modification and is high in safety; and the enzymolysis process is low in cost, easy to scale and suitable for functional food or medicine development. In addition, the invention provides the application value of 8-aminooctanoic acid as a lipid metabolism disorder marker for the first time, and expands the application scene of EMIP in preparation of diversified products for regulating intestinal flora, improving liver injury, reducing oxidative stress and the like.

The invention relates to the field of cosmetics, in particular to skin moistening oil containing a water-soluble active matter and a preparation method of the skin moistening oil. The skin moistening oil of the water-soluble active matter is prepared from the following raw materials in parts by mass: 0.1-1 part of a phase A, 3-15 parts of a phase B and 80-100 parts of a phase C, wherein the phase A is a water-soluble component, and the water-soluble component comprises one or more of deionized water, VC ethyl ether and nicotinamide; the phase B is a solvent, and the solvent comprises one or more of ethyoxyl diethylene glycol, 1, 2-pentanediol, isopentanediol and isostearic acid; the phase C is skin moistening oil, and the skin moistening oil comprises caprylic / capric triglyceride. The skin moistening oil product provided by the invention has the advantages of clear and transparent appearance, good fluidity, excellent stability, no need of adding a surfactant or a solubilizer, mildness, no irritation, simple process, controllable cost, good practical value and good application prospect.

The invention belongs to the technical field of female private part nursing, and particularly relates to andrographolide gel as well as a preparation method and application thereof. The invention provides an andrographolide gel, which is prepared from the following components in parts by mass: 0.1 to 0.5 part of andrographolide, 2.0 parts of caprylic / capric polyethylene glycol glyceride, 5.0 parts of propylene glycol, 0.05 to 0.2 part of chitosan, 10.0 parts of 1 percent W / V lactic acid solution, 0.15 to 0.6 part of hydroxyethyl cellulose and 30.0 parts of water. The andrographolide, the caprylic / capric polyethylene glycol glyceride, the propylene glycol, the chitosan, the 1% W / V lactic acid solution, the hydroxyethyl cellulose and the water are combined for use, the proportion of the components is strictly limited, and the obtained andrographolide gel can effectively inhibit vaginal pathogenic bacteria (including candida chromosomes, escherichia coli, staphylococcus aureus and gardnerella); the traditional Chinese medicine is used for treating fungal vaginitis and has no irritation to vaginal tissues.

The invention discloses a composition containing achillea millefolium extract, which is prepared from the following ingredients in percentage by weight: 45 to 55 percent of glycerol, 4 to 6 percent of hydrogenated lecithin, 3 to 5 percent of caprylic / capric triglyceride, 1 to 3 percent of 1, 2-hexanediol, 0.8 to 1.2 percent of achillea millefolium extract, 0.4 to 0.6 percent of ergothioneine and the balance of water. Through precise compounding of the achillea millefolium extract and the ergothioneine, the dual effects of anti-inflammation and skin repair are achieved, flavonoid and organic acid components in the achillea millefolium extract can effectively inhibit release of inflammatory mediators such as IL-6 and TNF-alpha, and sensitive symptoms such as red and swollen and pruritus are relieved.

The invention relates to the technical field of skin care products, and particularly discloses a composition based on anti-fatigue giant salamander peptide and a preparation method and application thereof. The andrias davidianus peptide mask is prepared from the following raw materials: 3 to 5 parts of a humectant, 3 to 8 parts of a thickening agent, 4 to 5 parts of an emulsifier, 0.1 to 0.3 part of an antibacterial preservative, 0.03 to 0.06 part of andrias davidianus peptide, 0.05 to 0.1 part of sodium hyaluronate, 0.1 to 0.2 part of carbomer, 5 to 8 parts of caprylic / capric triglyceride, 60 to 70 parts of deionized water, 1.2 to 1.5 parts of modified beta-cyclodextrin and 0.3 to 0.1 part of a modified chitosan compound. When the anti-fatigue giant salamander peptide-based composition is applied, the giant salamander peptide contained in the anti-fatigue giant salamander peptide-based composition is not easily damaged due to external environment change, and can stay on the skin surface layer for a long time.

The present invention belongs to the technical field of cosmetics, and specifically relates to a skin care composition with repairing and anti-aging effects, wherein the skin care composition comprises the following components in parts by weight: 2.5-4 parts of common wheat extract, 0.1-1 parts of phospholipids, 1-2 parts of squalane, 2.5-4 parts of caprylic / capric triglycerides, 0.5-1.5 parts of glycolipids, 0.01-0.5 parts of phytosphingosine, 0.001-0.1 parts of ceramide NS / ceramide NG, 0.05-3 parts of gentian root extract, 0.1-2 parts of sea fennel extract, 0.01-0.5 parts of milo leaf / stem extract, 0.01-1.0 parts of rose extract, and 0.01-0.8 parts of schizonepeta extract. The skin care composition of the present invention has repairing and anti-aging effects, and can be used to prepare sebum biomimetic cosmetics.