1197 results about "Caprylic acid" patented technology

The invention discloses an amphiphilic triblock copolymer with acid sensitivity and a preparation method and an application thereof. The preparation method comprises the following steps of: modifying polyethylene glycol with a hydroxyl group at the end to enable the structure of polyethylene glycol to contain a diazido ethyl diacetal end group, namely polyethylene glycol contains the diazido ethyl diacetal group at the end; carrying out ring-opening polymerization on cyclic ester monomers by utilizing propargyl alcohol as an initiator and stannous caprylate as a catalyst to obtain biodegradable polyester with alkynyl at the single end; and finally, under the action of a 'click' chemical catalyst and ligand, carrying out 'click' chemical reaction on polyethylene glycol containing the diazido ethyl diacetal group at the end and the biodegradable polyester with alkynyl at the end to obtain the biodegradable amphiphilic triblock copolymer with acid sensitivity. The biodegradable amphiphilic triblock copolymer with acid sensitivity has good biocompatibility, biodegradability and acid sensitivity, and can be used as a drug carrier.

The invention discloses an acne treatment composition and application thereof and an acne treatment cream containing the acne treatment composition. The acne treatment composition comprises shea butter, Chinese corktree bark extract, salix nigra bark extract, herba portulacae extract, purple perilla extract, asiatic pennywort herb extract and mung bean extract, effectively conditions acne skins and inhibits reproduction of acne, smoothens acne and removes acne marks, and can be applied to skin directly or added into acne treatment products. The acne treatment cream comprises the acne treatment composition, cetearyl alcohol, ethylhexyl palmitate, polydimethylsiloxane, glyceryl stearate, PEG-100 stearate, caprylic/capric triglyceride, propylene glycol, polyacrylamide, polysorbate-60, sorbitan stearate, laurocapram, PEG-20 methl glucse sesquistearate, menthol, borneol, edta disodium, methylparaben, propyl hydroxybenzoate and water. The acne treatment cream prepared by a hypo-allergenic formula is mild and non-irritating, easy to absorb, non-greasy, safe and effective.

The invention discloses a fluorine and silicon containing water and oil repellent finishing agent which is synthesized from fluorine containing acrylic ester formed by fluorine containing alkyl with a shorter carbon chain and double-bond containing organic siloxane as basic structural units. On one hand, the advantages of a fluorine containing water and oil repellent finishing agent is retained; and on the other hand, the fluorine containing acrylic ester formed by the fluorine containing alkyl with a shorter carbon chain is selected so that perfluoro caprylic acid (PFOA) and salt thereof toxic to the environment are prevented from being generated in the degradation process of the fluorine and silicon containing water and oil repellent finishing agent. By combining the advantages of the silicon and the fluorine, the fluorine and silicon containing water and oil repellent finishing agent of the invention becomes a fabric finishing agent which has excellent performance and is environmentally friendly.

The invention discloses a preparation method of an oil-water separation net membrane with super-hydrophilic lipophobicity. The method comprises the steps that a red copper net serves as a substrate; a micro-nano needle structure is constructed by a simple solution soaking method; surface modification is performed by a poly dimethyl diallyl ammonium chloride-sodium perfluorooctanoate/ silica compound. The prepared oil-water separation net membrane with the super-hydrophilic lipophobicity is used for oil-water separation. The method has the advantages that the preparation method of the oil-water separation net membrane with the super-hydrophilic lipophobicity is simple, short in time consuming and stable in performance, and requires no large instrument; the prepared oil-water separation net membrane is easy to clean and good in recycling; water permeation instead of oil permeation can be achieved when the net membrane provided by the method is applied to the oil-water separation; the net membrane can effectively perform the oil-water separation on vegetable oil and gasoline, and has a wide application prospect in the oil-water separation.

The invention discloses an acne removing cosmetic and a preparation method thereof. The cosmetic comprises, by weight, A components, B components, C components and D components, wherein the A components include, by weight, 64%-78% of deionized water, 0.01%-0.2% of sodium hyaluronate, 2%-10% of 1,3-butanediol, 0.5%-1% of acryloyl dimethyl taurine ammonium/ pyrrolidone (VP) copolymer, 0.15%-0.5% of acrylics (esters)/ vinyl alcohol isodecyl acid ester cross-linked polymer sodium and 0.15%-0.5% of triethanolamine; the B components include, by weight, 0.5%-5% of honey extract, 1%-3% of LS9088, 0.5%-2.0% of phellodendron extract, 1%-3% of hydrolysis opuntia ficus-indica flowers, 0.5%-1.5% of vitex agnus-castus extract, and 2%-6% of caprylic acid propyl heptyl ester; C components include, by weight, 2%-10% of jojoba oil and 2%-5% of polydimethylsiloxane; and D components include, by weight, 0.2%-1% of preservative and 0.1%-0.3% of essence.

The invention discloses a non-additivated antisenescence cosmetic, which comprises the following components by weight: a component A composed of glycerin, propylene glycol, hydroxyethyl urea, allantoin, sodium hyaluronate and water; a component B composed of MONTANOV68, dipalmitoyl hydroxyproline, caprylic/capric triglyceride, shea butter, jojoba oil, tocopheryl acetate, polydimethylsiloxane, wheat germ oil and COSMOFERMMI XIII; a component C composed of hydroxyethyl acrylate/acryloyl dimethyltaurate crosspolymer; a component D composed of nicotinamide, panthenol, beta-glucan, mycose and water; a component E composed of acetyl Hexapeptide-8 and water; and a component F composed of SYMDIOL68T and SYMTRIOL. The antisenescence cosmetic has good antisenescence effect, simultaneously, no harmful antiseptic is added in the cosmetic.

The invention discloses a dutasteride soft capsule preparation, comprising a soft capsule and contents. A prescription for the contents comprises 0.5 g of a dutasteride raw material, 200 to 250 g of labrasol, 30 to 60 g of polyglycerol oleate, 50 to 100 g of medium-chain triglyceride and 0.02 to 0.05 g of 2,6-di-t-butyl p-cresol. The dutasteride soft capsule prepared in the invention is substantially improved in accumulated dissolution in 5 minutes of dissolving-out and enhanced in the dissolving-out efficiency of a main drug in a preceding time period and has good stability and good appearance quality.

The invention relates to a targeted polymer medicament carrier and a preparation method and application thereof. The targeted polymer medicament carrier has a molecular structural formula shown in the graph. The preparation method comprises the following steps of: a) feeding Pluronic and Biotin in a molar ratio of 1:1.1-1.5; dissolving the mixture in dichloromethane; adding 4-dimethylamino pyridine; dropwise adding 1,3-dicyclohexyl carbodiimide in an ice water bath; reacting at room temperature for 24 to 48 hours; extracting reactive fluid with 10 to 15 percent NaHCO3; freezing over night; filtering to remove undissolved substances; concentrating the reactive fluid; dropping the reactive fluid into cold absolute ethyl ether; filtering, and drying in vacuum; and b) dissolving a product with dry toluene, and distilling the product in the presence of argon gas; dehydrating by an azeotropy method; cooling to the room temperature; adding lactide according to 50 to 90 percent of the weight of the product in the presence of the argon gas, and adding stannous octoate according to 0.1 to 0.15 percent of the weight of the lactide; heating to the temperature of between 120 and 140 DEG C; reacting for 6 to 8 hours under stirring; immersing a reactant into the cold ethyl ether, and filtering; and dissolving polymer by using dichloromethane, immersing into methanol, and filtering and drying. The carrier can be used as carriers of medicaments for treating and diagnosing cancers.

A composition and method for promoting neutrophil survival and activation such as the treatment of neutropenia arising as an undesirable side effect of chemotherapy and radiation therapy. A composition containing medium-chain fatty acids, such as Capri acid or caprylic acid, or salts or triglycerides thereof, or mono- or diglycerides or other analogues thereof or medium-chain triglycerides (MCT) is administered to a human or animal needing treatment in an amount sufficient to reduce or eliminate neutropenia. The composition is administered in an amount effective to treat the disorder. The methods are also useful in the management of bone narrow transplantation and in the treatment of various neutropenic diseases.

The invention provides whitening essence and a preparation method thereof. The whitening essence consists of the following components of glycerine, 1,3-butanediol, sodium hyaluronate, EDTA-2Na, polyglycerol-10, sodium polyacrylate, xanthan gum, hydroxyacetophenone, dipotassium glycyrrhizinate, hydrolyzed sclerotium gum, gluconic acid sodium salt, glycereth-26, caprylhydroxamic acid, glycerol caprylate, 3-o-ethyl ascorbic acid, tranexamic acid, ceramide, phenethyl resorcinol, diglucosyl gallic acid and water. The whitening essence disclosed by the invention can refrain conversion of tyrosine tomelanin before the tyrosine is in preparation of conversion to the melanin, so that the activity of the tyrosinase is also high, generation of more melanin cannot be caused, and transfer of skin melanin can also be restrained. Besides, the whitening essence has powerful antioxidant ability, has light protection effects on skin, can control dermatitis, and is a whitening product most comprehensivein action mechanism at present, so that whitening effects can be achieved.

The invention discloses a BB cream having whitening, moisturizing and makeup-dizziness preventing functions. The BB cream consists of the following components: glycerol, cyclopentasiloxane, titanium dioxide, cetyl ethyl hexanoate, cetyl PEG/PPG-10/1 polydimethylsiloxane, dipropylene glycol, nicotinamide, caprylic/capric triglyceride, ethylhexyl palmitate, PEG-75 meadowfoam seed oil, hydrogenated polydecene, sodium chloride, quaternary ammonium salt-18 bentonite, white beeswax, argania spinosa kernel oil, tocopherol, CI 77492, panthenol, CI 77491, CI 77499, phenoxyethanol, allantoin, methylparaben, propyl hydroxybenzoate, sodium hyaluronate, essence, EDTA disodium, butylated hydroxytoluene, adenosine and water. By virtue of the meadowfoam seed oil, the adenosine, the argania spinosa kernel oil, the panthenol and the nicotinamide, the functions of the finished BB cream are effectively expanded, so that the BB cream is better in moisturizing performance, makeup-dizziness preventing performance and whitening performance.

The invention relates to an antioxidant network efficacy nanoemulsion externally used for skin and a preparation method thereof. The nanoemulsion consists of the following raw materials according to weight mixture ratio: 1.0-1.5 of vitamin E, 2.0-3.0 of glutathione, 2.0-2.5 of L-ascorbic acid-2-heteroside, 1.0-1.8 of seabuckthorn oil, 1.0-1.6 of coenzyme Q10, 0.5-0.6 of alpha-lipoic acid, 8.0-10 of isopropyl myristate, 20-25 of caprylic acid capric acid polyethylene glycol glyceride, 7.0-9.0 of polyglyceryl fatty acid ester, 0.5-1.0 of azone, 46-50 of triple distilled water, 0.05-0.25 of citric acid and 1.0-1.6 of sodium citrate. The functional ingredients in the formula can form an antioxidant network system with cooperative interaction, synergy and regeneration, and the penetrating function of a nanoemulsion carrier system greatly enhances the antioxidant function and effect of the functional ingredients. The preparation method can enhance the stability and effectiveness of antioxidant, is simple in preparation technology and easy for scale production, needs no extra energy, saves time, energy and raw materials and is beneficial to environment protection.

The invention discloses a lactic acid-tolerant ester-producing pichia pastoris, and belongs to the technical field of a bioengineering technology and a brewing biotechnology. The strain is preserved at the General Microbiology Center of the China Committee for Culture Collection of Microorganisms on April 24, 2017, the classification is named pichia kudriavzevii (Pichia kudriavzevii) and the preservation number is CGMCC No.14068. The pichia pastoris is high in environmental tolerance, is capable of tolerating 0-15% lactic acid, is capable of metabolizing to generate multiple ethyl ester volatile flavor substances, such as ethyl acetate, ethyl propionate, ethyl caprylate, phenethyl acetate and ethyl phenylacetate in the environment of 0-12% lactic acid, and is a brewing functional strain with excellent performance.

The invention relates to a method for separating and purifying triglyceride of medium- and long-chain fatty acids. Triglyceride mixture of medium- and long-chain fatty acids is obtained from rapeseed oil, soybean oil or rice bran oil and caprylic acid as raw materials by one-step enzymatic acidolysis with 1, 3 specific lipase as catalyst. Further separation and purification steps of the above triglyceride mixture include: (1) performing first-stage molecular distillation on the mixture in molecular distillation device to obtain heavy phase; and (2) performing second-stage molecular distillation on the heavy phase in molecular distillation device to give product, which has purity of triglyceride of medium- and long-chain fatty acids up to 88.31-93.11% and acid value reduced to below 2.10 mgKOH/g. The invention realizes substance separation by difference in average free path of molecular movement of different substances, and has the advantages of low distillation pressure, short heatingtime, low operating temperature, high product quality, and high separation and purification degree.

The invention discloses a gas-phase rust-preventing aerosol and a preparation process thereof. The formula of the gas-phase rust-preventing aerosol comprises the following components in parts by mass: 0.5-1.5 parts of caprylic acid tributylamine, 1-3 parts of benzotriazole tributylamine, 2.5-3.5 parts of oleic acid, 1-3 parts of laurinol, 0.2-0.8 part of amino silicon oil, 2.5-3.5 parts of methyl oleate, 0.2-0.8 part of sodium petroleum sulfonate, 0.2-0.8 part of barium petroleum sulfonate, 0.5-1.5 parts of capric acid tributylamine, 51.5-61.5 parts of 20# machine oil and 27-33 parts of liquefied petroleum gas. The process comprises the following steps: mixing and stirring the raw materials; filling the obtained liquid into a spray can; inserting a capillary valve; filling the liquefied petroleum gas; performing leak detection, and blowing-dry; and boxing, and warehousing. The invention has the characteristics of small aerosol particle diameter and high aerosol particle uniformity DR, and can effectively enhance the corrosion inhibition effect of a metal component.

The invention discloses a nursing agent for skin moisturizing and repairing. The nursing agent for skin moisturizing and repairing comprises the following components by mass percentage: 0.05 0.15% ofdisodium EDTA, 0.5-3.0% of nicotinamide, 2.0-5.5% of glycerin, 2.5-5.5% of propylene glycol, 0.05-0.35% of xanthan gum, 0.05-0.5% of sodium hyaluronate, 0.15-0.5% of p-hydroxyl acetophenone, 1.0-5.0%of caprylic/capric triglyceride, 1.0-3.0% of polydimethylsiloxane, 1.0-5.0% of isononyl isononanoate, 0.5-5.0% of jojoba seed oil, 0.5-2.5% of avocado tree fruit oil, 1.75-10.5% of repair essential oil, 0.05-0.5% of fullerenes, 0.35-2% of repairing essence, 0.2-3.5% of cetostearyl alcohol, 1.0-2.5% of cetearyl olivate, 1.0-2.5% of sorbitan olivate, 0.1-1.0% of lecithin, 0.5-5.0% of oligopeptide-1, 0.1-0.5% of D-panthenol, 0.5-2.5% of a Centella asiatica extract, 0.5-2.5% of 1,2-hexanediol, and the balance of deionized water. The product of the invention can quickly improve the moisture retention of the skin, obviously improves the dryness of the skin, increases the moisture content in the skin, and makes the skin appear young. .