116 results about "GLYCERYL STEARATE" patented technology

The invention relates to the field of foaming materials, in particular to a low-solvent-residue expandable polystyrene material and a preparation method thereof. The expandable polystyrene material with low solvent residue comprises the following raw materials in percentage by weight: 0.35-0.45% of a free radical initiation system, 0.35-0.45% of S, S, S, S, S, S, S, S, S, S, S, S, S, S, S According to the present invention, the material comprises, by weight, 0.1-0.15% of S, S '-bis (alpha, alpha'-dimethyl-alpha ''-acetoxy) trithiocarbonate, 0.15-0.2% of ascorbic acid, 0.1-0.2% of a nucleating agent, 0.2-0.3% of a suspending agent, 0.001-0.003% of an emulsifier, 5-6% of a foaming agent, 0.15-0.25% of a plasticizer, 0.001-0.002% of hydroxyethyl cellulose, 0.05% of sodium phosphate, 0.1-0.2% of zinc stearate, and 0.1-0.2% of glyceryl stearate, the obtained material has low solvent residue, meets food safety requirements, and is suitable for food packaging.

The invention discloses a biological challenge device with combined adjustable resistance for evaluating the effect of a sterilization process, which comprises a shell, the shell comprises a plastic pipe and an inner pipe cap detachably connected with the inner wall of the plastic pipe, the inner pipe cap is provided with a breathable window and covered by a breathable film, and a bacterial contamination carrier for bearing indicator biological spores is attached to the inner bottom of the plastic pipe. An openable container containing a liquid culture medium is arranged in the plastic pipe cavity; the outer side of the inner pipe cap is sleeved with an outer pipe cap detachably connected with the outer wall of the plastic pipe, and the outer pipe cap is provided with a flow blocking structure used for adjusting the speed of the sterilizing agent entering the area of the inner pipe cap; the indicator biological spores are pretreated by a stable protective agent containing one or more of polyethylene glycol, trehalose, sorbitol, polyvinylpyrrolidone and glyceryl stearate. The speed of a sterilizing agent entering the device can be limited, the spores are dry in a suspension added with a stable protective agent, the capability of resisting general environmental changes is very good, and the performance of the device can be maintained for a long time.

The invention relates to the technical field of repair compositions, and discloses a repair composition based on mussel mucin and application of the repair composition in skin barrier repair. The invention discloses a mussel mucoprotein-zinc composite microcapsule repair agent, which is prepared from the following components in parts by weight: mussel mucoprotein-zinc composite microcapsules, modified carboxymethyl chitosan, isolactone palmitate, a pH response type ceramide slow release system, dimeticone, cetostearyl alcohol, a calcium ion activating agent, an auxiliary repair factor, beheneth-25, caprylic / capric triglyceride, glyceryl monostearate, glyceryl distearate, pentanediol and citric acid. The preparation method comprises the following steps: adding ethanol, phenoxyethanol / ethylhexylglycerin, trehalose, beta-glucan and purified water; according to the whole technical scheme, through functional complementation and process optimization of all the components, synergistic interaction is achieved, the transpedermis water loss amount can be rapidly reduced, the water content of the skin cuticle is increased, the damaged skin barrier structure can be repaired from the source, and the resistance and stability of the skin are remarkably improved.

This invention relates to a low-irritation soothing composition and its application, belonging to the technical field of skin care products. The low-irritation soothing composition, by weight percentage, comprises 0.05–0.2 wt% kava soothing agent, 0.3–1.0 wt% pine nut extract, 1.8–2.5 wt% a mixed emulsifier composed of cetearyl alcohol and glyceryl stearate, wherein the mass ratio of cetearyl alcohol to glyceryl stearate is 2.5–3.5:1; 2.0–5.0 wt% moisturizer, 0.4–1.0 wt% preservative, 0–2.0 wt% cosmetically acceptable excipients, and the balance being water. This invention utilizes the synergistic effect of low concentrations of kava soothing agent and pine nut extract, and employs a low total fat emulsification system to form a delicate and stable O / W emulsion, reducing transepidermal water loss and repairing the physical barrier; together, they maintain a low-inflammatory, low-oxidative, and microbial balanced microenvironment, providing ideal conditions for barrier repair.

This invention belongs to the field of pharmaceutical chemistry, and specifically relates to a compound antifungal cream containing the traditional Chinese medicine ingredient tryptamine ketone and its application. The invention comprises the following components, with the following percentage content: stearic acid 10%~16%, glyceryl monostearate 3%~7%, liquid paraffin 5%~9%, tryptamine 0.1%~0.01%, terbinafine hydrochloride 0.00625%~0.000625%, glycerin 4%, triethanolamine 2%~6%, ethylparaben 0.5%, and the balance being purified water or distilled water. This invention is highly effective, low in toxicity, and exhibits low drug resistance.

The invention relates to the technical field of pharmaceutical preparations, and particularly discloses an anti-inflammatory analgesic indometacin long-acting suppository and a preparation method thereof.The suppository is composed of indometacin sustained-release microspheres and a modified fatty matrix; eudragit RS100 / RL100 is used as a compound framework of the sustained-release microspheres, the sustained-release microspheres are prepared through a spherocrystal granulation process, the modified fatty matrix is prepared from a mixed fatty glyceride compound matrix sustained-release aid, a three-dimensional suspending dispersant and the like through melting, pre-crystallization and high-speed homogenization processes, and the three-dimensional suspending dispersant contains modified nano silicon dioxide, glycerin monostearate and beewax. According to the invention, a microsphere-matrix dual controlled release system is constructed, so that burst release of drugs is eliminated, and long-acting stable release is realized; the microspheres are prevented from settling and agglomerating through a physical locking mechanism, and the storage stability of the preparation is improved by matching with a dual anti-oxidation system; meanwhile, rectal mucosa stimulation is reduced, the preparation process is simple, the quality is controllable, and the composition is suitable for anti-inflammation and analgesia of various diseases and has a wide clinical application prospect.

The application relates to the technical field of degradable materials, and discloses a high-mechanical-property PLA degradable composite material and a preparation method thereof.The high-mechanical-property PLA degradable composite material comprises the following raw materials in parts by weight: 60-80 parts of PLA resin, 15-30 parts of PBS resin, 5-12 parts of Chinese pine powder, 10-15 parts of polycaprolactone, 0.1-3 parts of a modified toughening agent, 0.2-1 part of a modified light stabilizer, 0.1-1 part of antioxidant 1010, 1.5-3 parts of glycerol tristearate, 0.1-0.5 parts of sodium benzoate and 0.1-0.5 parts of silane coupling agent KH-550.The modified toughening agent improves the impact strength and flexibility of the material, and further widens the application scene of the material; the modified light stabilizer enhances the ultraviolet aging resistance of the material, and meanwhile, the material retains excellent degradable characteristics and can be efficiently degraded in a natural environment after being discarded.

The invention discloses snowflake cream with pearly luster and a preparation process of the snowflake cream. The snowflake cream comprises the following raw material components: a phase A: water; butanediol; glycerol; methyl glucitol polyether-20; a polyacrylate cross-linked polymer-6; sodium hyaluronate; potassium hydroxide (90%); 4-hydroxyacetophenone; xanthan gum; phase B: caprylic / capric triglyceride; cetostearyl alcohol; stearic acid; a polydimethylsiloxane; squalane; simmondsia chinensis seed oil; mineral oil; and polyethylene glycol (PEG)-100 stearate. Glyceryl stearate; tocopheryl acetate; isononyl isononanoate; a phase C: 1, 2-hexanediol; carnosine; a centella asiatica extract; collagen; the snowflake cream has the advantages of uniform pearly luster texture and the advantages of traditional snowflake cream.

The application discloses heparin sodium cream and a preparation method thereof, and belongs to the technical field of pharmaceutical preparation production. The heparin sodium cream comprises the following components: heparin sodium, propylene glycol, hydroxyphenyl ethyl ester, sodium dodecyl sulfate, glycerol monostearate and distearate, octadecanol, liquid paraffin, white vaseline and water. The preparation method comprises the following steps: preparing an oil phase and mixing an aqueous phase; taking part of the mixed aqueous phase and the oil phase to form a water-in-oil type primary emulsion; then adding the remaining mixed aqueous phase into the primary emulsion, inducing phase transition into an oil-in-water type cream under mild conditions, and obtaining the finished product after vacuum defoaming and gradient cooling. The application realizes high-efficiency emulsification under mild conditions below 80 DEG C and 3000 rpm through a controlled phase inversion emulsification process, so that the particle size (D99) of the emulsion droplets is less than 5 microns, and the problem that the active substance heparin sodium loses activity under severe conditions is solved completely, and the stability of the product is improved significantly.

The invention relates to the technical field of polyethylene films, and particularly discloses a low-precipitation polyethylene film and a preparation method thereof. The low-precipitation polyethylene film is prepared from the following raw materials: polyethylene, silicon carbide nanowires, nano talcum powder, an antioxidant and glyceryl stearate. The alkane precipitation amount of the obtained polyethylene film is 5 ppm or below, and precipitation of alkane molecules of the polyethylene film is obviously reduced.

The invention relates to low-fat fragrant and sweet salad dressing and a preparation method thereof, and belongs to the technical field of food processing. The salad dressing comprises functional components such as carrageenan, arginine, microfibrillated cellulose, glyceryl monostearate, hydroxypropyl cyclodextrin, soybean lecithin and vegetable oil according to a specific proportion. The preparation method is characterized in that glyceryl monostearate, hydroxypropyl cyclodextrin and soybean phospholipid are melted, mixed and crystallized in advance to form solid composite particles which can be melted in an oral cavity in a phase change manner, so that a strong flavor outbreak feeling and a mellow taste are provided; meanwhile, the salt is slowly released by utilizing the electrostatic interaction of the carrageenan and the arginine in the system; and by combining a three-dimensional network constructed by microfibrillated cellulose, the product is endowed with excellent oil-water separation resistance. While the content of fat and sodium is reduced, the problems of insufficient flavor and poor stability of the traditional low-fat sauce can be improved.

The application provides a white-borneol apricot kernel face mask liquid and a preparation method and application thereof, and relates to the technical field of cosmetics. The preparation raw materials of the white-borneol apricot kernel face mask liquid provided by the application include white petrolatum 5-20 parts, mono-diglyceride 1-10 parts, methyl p-hydroxybenzoate 0.01-8 parts, glycerol 1-10 parts, butanediol 0.05-10 parts, Tween-80 0.05-12 parts and compound extraction liquid 10-30 parts in terms of weight percentage. The white-borneol apricot kernel face mask liquid provided by the application has good moisturizing effect, is cold and heat resistant, has good stability and meets the microbial detection standard of cosmetics.

This invention discloses a coal liquefaction residue-based warm-mix self-healing dual-function asphalt modifier and its preparation method, belonging to the field of road engineering materials technology. The modifier consists of the following components by mass percentage: plasma-activated coal liquefaction residue micropowder (40-60%), warm-mix functional agent (10-20%), self-healing microcapsules (15-25%), interface reinforcing agent (5-10%), and coupling agent (2-5%). The plasma-activated coal liquefaction residue micropowder has a particle size of 0.15 mm, a specific surface area of ​​300-400 m² / g, and a surface hydroxyl content of 1.2-2.0 mmol / g. Its porous structure is used to adsorb and slowly release the warm-mix functional agent, and also serves as a carrier for the microcapsules. The warm-mix functional agent is a compound of sodium alkylbenzene sulfonate / polyoxyethylene ether and glyceryl stearate / methyl oleate, which are oriented at 120-130℃ to form a lubricating interface layer, reducing the viscosity of the asphalt mortar by more than 30%. The self-healing microcapsules use polyurethane as the shell material and contain asphalt recycler, sulfur, and plasticizer in the core material. They can rupture and release the core material when microcracks propagate.

The application discloses an anti-permeation low-shrinkage inorganic coating and a preparation method thereof. The anti-permeation low-shrinkage inorganic coating comprises cement material 40-60 parts by mass, active mixed material 15-30 parts by mass, gypsum 5-15 parts by mass, talcum powder 5-15 parts by mass, glycerin stearate 0-2 parts by mass and additive 4.7-6.7 parts by mass. The application selects green inorganic material, combines the characteristics of slow hydration of low-heat Portland cement, micro-expansion of high-magnesium low-heat Portland cement and micro-expansion of ettringite-like product formed between gypsum and cement hydration product, uses micro-expansion to relieve the shrinkage problem of the material, makes the material form a dense structure, and makes the material have the hydrophobic anti-permeation characteristics through the saponification reaction of glycerin stearate under alkaline conditions.

The invention discloses a high-toughness composite PVC film and a preparation method thereof. The high-toughness composite PVC film is prepared from the following components in parts by weight: 62 to 74 parts of PVC resin, 54 to 67 parts of oxidized polyethlene wax, 25 to 35 parts of silicon dioxide, 26 to 39 parts of aconitic acid monoester, 14 to 28 parts of terephthalic acid, 24 to 36 parts of silane coupling agent, 16 to 28 parts of ethylene propylene diene monomer, 14 to 18 parts of glyceryl stearate, 14 to 19 parts of rare earth stearic acid and 16 to 26 parts of oleamide. Compared with a film at the present stage, the PVC film provided by the invention forms a more stable spatial network structure, can further increase the air permeability, can effectively play a supporting effect, has higher toughness, and is mainly embodied in high elongation at break, high falling standard impact strength, improved impact strength and improved air permeability of the film.

The present application relates to the technical field of high polymer materials, and particularly relates to a reversible color-changing microcapsule high-temperature-resistant coating and a preparation method thereof, which comprises the following components in mass ratio: inorganic polysiloxane resin 30%-40%, hydroxyl acrylic resin 10%-20%, additive 2%-5%, solvent 5%-15%, white corundum 5%-10%, silicon powder 10%-15%, and reversible color-changing microcapsule pigment 5%-15%; the reversible color-changing microcapsule pigment is synthesized by core material and wall material, and through the synergistic design of organic-inorganic hybrid wall material (methyl polysiloxane prepolymer, acrylic prepolymer and nano silicon dioxide composite) and core material phase change medium (glyceryl stearate), the problems such as insufficient high-temperature resistance of traditional thermochromic coating, slow color-changing response and poor mechanical stability of microcapsules are effectively solved.

This invention discloses a skin cream for chapped hands and feet and its preparation process, belonging to the field of skin cream preparation technology. The skin cream is composed of ginseng leaf and stem extract, royal jelly, glycerin, octadecanol, glyceryl stearate, liquid paraffin, sodium lauryl sulfate, ethylparaben, fragrance, and purified water in a specific mass ratio. Its preparation process includes steps such as heating and melting the oil and water phases separately, emulsifying and stirring, cooling and adding active ingredients, and aging. This product, through the synergistic effect of moisturizing and active repairing ingredients, can effectively relieve dry and cracked skin, promote healing, and has the advantages of stable formula, gentle skin feel, and high safety.

The application discloses a nemonoxacin malate capsule and a preparation method thereof, and belongs to the technical field of pharmaceutical preparations. The nemonoxacin malate capsule comprises the following components in parts by weight: 80-90 parts by weight of nemonoxacin malate hemihydrate, 10-20 parts by weight of a filler, and 1 part by weight of a hollow capsule. The filler is composed of essential components and optional components. The essential components are anhydrous lactose and glycerin monostearate compound. The optional components are selected from one or more of polyethylene glycol, hydrogenated vegetable oil, sodium aluminum silicate, magnesium stearate, glycerin distearate, microcrystalline cellulose, chitosan and anhydrous trisodium phosphate. The novel excipients not only effectively establish the good in-vivo and in-vitro correlation of the nemonoxacin malate capsule, but also improve the problems of large individual drug difference and poor stability.

The invention relates to the field of daily chemical products, and particularly discloses a bartana oil hair heat protection hair conditioner and a preparation method thereof, the bartana oil hair heat protection hair conditioner comprises the following components: a group A: water, cetrimonium chloride and hydroxyethyl cellulose; the group B is prepared from the following raw materials: PEG-50 shea butter, a papain oil nutrient solution, a siloxane emulsion, glyceryl stearate, PEG-20 stearate, p-hydroxyacetophenone, PEG-50 stearate, polydimethylsiloxane alcohol and PEG-100 stearate; group C: essence and phenoxyethanol; group D: panthenol, hydrolyzed keratin, vitamin complex, tridecanol polyether-12, ethylhexylglycerin, citric acid and natural carotene; the added siloxane emulsion and the bartana oil nutrient solution form a double-membrane structure, the double-membrane structure can penetrate into hair cuticle gaps to fill up damaged areas, a hydrophilic-hydrophobic composite membrane is constructed on the surface of hair, the heat conduction efficiency is reduced, the heat insulation threshold value of the hair conditioner is increased, and the prepared hair conditioner has the three-effect-in-one deep repairing and nourishing effects of heat insulation, repairing and scalp protection.

Methods of making stable, dry coated fruit powders are provided. The methods include providing a fruit powder; selecting a hydrophobic stearate guest particle from the group consisting of ammonium stearate, zinc stearate, calcium stearate, sodium stearate, potassium stearate, magnesium stearate, glyceryl stearate, propylene glycol monostearate, sorbitan stearate, triglyceryl monostearate, hexaglyceryl distearate, and decaglyceryl monostearate; and dry coating the fruit powder with the hydrophobic stearate guest particles using high shear. The hydrophobic stearate guest particles are dry coated with respect to the fruit powder at levels between about 1 and 10 wt % in order to form a continuous layer.

The invention provides a microcellular foaming master batch composition for a controlled weight loss and controlled microcellular foaming plastic product. The microcellular foaming master batch composition comprises a thermoplastic carrier plastic, a two-component microcellular foaming agent comprising a gas carrier and an acid carrier, an amphiphilic stabilizer selected from a fatty acid modified salt, glyceryl stearate or a combination thereof, and an adsorption dispersant. The master batch composition is suitable for a wider processing temperature range to meet the requirements of producing various base material plastic foaming products, and allows controllable microcellular foaming in plastic products, so that the microcellular foaming plastic product which is lighter in weight, good in mechanical strength, low in cost and high in flexibility and meets the requirements of laws and regulations can be easily manufactured.

The application belongs to the field of composite materials, and provides a preparation method of a composite material of barium borate as a skeleton loaded with glycerol monostearate, GMS is dispersed in deionized water, heated and stirred, and then cooled to room temperature to form a suspension, barium nitrate and sodium tetraborate are dispersed in deionized water and stirred by a magnetic stirrer; the GMS suspension is added dropwise into the sodium tetraborate solution and stirred uniformly, the barium nitrate solution and the PEG-200 solution are added dropwise into the GMS and sodium tetraborate mixed solution in sequence and stirred uniformly, and then poured into a hydrothermal kettle for hydrothermal treatment; after hydrothermal treatment, the product is naturally cooled to room temperature, centrifuged or suction filtered, and the precipitate is washed with deionized water to obtain a BaB / GMS / PEG composite material. The product has excellent tribological properties. The preparation method of the composite material of barium borate as a skeleton loaded with glycerol monostearate has the advantages of simple synthesis process and green and environmentally-friendly reaction.

The invention relates to the technical field of dairy product processing, in particular to Chinese yam milk containing active protein and a preparation method thereof, and the Chinese yam milk comprises the following raw material components: raw milk, Chinese yam powder, gellan gum, sucrose fatty acid ester, glyceryl monostearate, glyceryl distearate, amylase, glucoamylase, food essence and water. According to the method, the Chinese yam and the milk are combined, a sweetening agent is not additionally added, meanwhile, the beverage is endowed with a sweet feeling, meanwhile, the damage of heat treatment to active protein in cow milk in the processing process is overcome, and the Chinese yam milk which is good in flavor and stable in system and contains the active protein is prepared.

A personal care composition having at least a cleansing phase and a benefit phase. The composition is substantially free of alkyl sulfate and alkyl ether sulfate type of surfactants. The cleansing phase includes: an alaninate surfactant; a zwitterionic or amphoteric surfactant; and a structuring system. The structuring system has from 0.5% to 5% of an emulsifying agent by weight of the composition. The emulsifying agent is a glyceryl ester and / or a non-ionic emulsifier having an HLB of from 3.4 to 13.0. The glyceryl ester is selected from glyceryl laurate, glyceryl caprate, glyceryl caprylate, glyceryl caprylate / caprate, glyceryl stearate, and a mixture thereof. The non-ionic emulsifier having an HLB of from 3.4 to 13.0 includes trideceth-3 or trideceth-4. The structuring system also includes from 0.01% to 10% of a rheology modifier by weight of the composition. The benefit phase includes from 0.1% to 50% of a benefit agent by weight of the composition. The personal care composition has a pH that is from 4.0 to 5.5.

The invention discloses heparin sodium cream and a preparation method thereof, and belongs to the technical field of pharmaceutical preparation production. The heparin sodium cream is prepared from the following components: heparin sodium, propylene glycol, ethylparaben, lauryl sodium sulfate, glyceryl monostearate and glyceryl distearate, octadecanol, liquid paraffin, white vaseline and water. The preparation method comprises the following steps: preparing an oil phase and a mixed water phase; emulsifying a part of the mixed water phase and the oil phase to form a water-in-oil primary emulsion; adding the residual mixed water phase into the primary emulsion, inducing phase transformation into oil-in-water emulsifiable paste under a mild condition, and performing vacuum defoaming and gradient cooling to obtain a finished product. Through a controlled phase inversion emulsification process, efficient emulsification is realized under mild conditions of 80 DEG C or below and 3000 rpm or below, the emulsion droplet particle size (D99) is less than 5 [mu] m, the problem that the active substance heparin sodium loses activity under severe conditions is thoroughly solved, and the product stability is significantly improved.

The invention discloses a raw fresh meat composite antibacterial fresh-keeping agent and a low-temperature synergistic fresh-keeping process, and relates to the technical field of food fresh-keeping. The preservative is formed by mixing a microcapsule component and an emulsion component, the microcapsule component is a microcapsule with epsilon-polylysine as a capsule core and a chitosan-nisin compound as a capsule wall, and the emulsion component comprises D-sodium erythorbate, lysozyme, tea polyphenol, glycerin monostearate and water. The fresh-keeping process comprises the following steps: immersing meat into a fresh-keeping agent, applying variable-frequency ultrasonic-assisted permeation, and storing at ice temperature. The fresh-keeping agent disclosed by the invention realizes full-period long-acting bacteriostasis of the fresh meat. The process disclosed by the invention realizes high-efficiency permeation of the preservative and low-loss storage of meat products, and is suitable for industrial preservation of fresh meat and industrial popularization of food.

This invention relates to a modified long-acting sustained-release coating agent for topical liquid formulations, its preparation method, and its application, belonging to the field of pharmaceutical preparations. The modified long-acting sustained-release coating agent for topical liquid formulations comprises a carrier and a topical liquid formulation in a mass ratio of 1:1 to 3:2. The carrier includes PVA, glycerin, liquid paraffin, β-hydroxyethyl urea, glyceryl stearate, PEG stearate, and purified water. The topical liquid formulation includes one or more of the following: tincture, liniment, solution, lotion, ointment, oil, and rinse. This invention's long-acting sustained-release coating agent is a universal coating agent, safe to use, non-irritating, and has no incompatibility with topical liquid formulations. It facilitates film formation, has a short film-forming time, and produces a flexible film that is not easily detached.

The invention discloses a bacteriostatic liposome with lipase responsiveness, a preparation method and application thereof and a product, and belongs to the technical field of cosmetics. The invention aims to solve the technical problems of drug resistance, high skin irritation and the like of the existing acne treatment means. Meanwhile, antibacterial core materials such as totarol and the like have the problems of poor solubility, poor transdermal absorption, burst release stimulation and the like. According to the key point of the technical scheme, the bacteriostatic liposome with lipase responsiveness is provided, and a wall material of the bacteriostatic liposome comprises soybean phosphatidylcholine, hydrogenated phosphatidylcholine, cholesterol, PEG-7 olivate, glyceryl stearate and ceramide NP, the inner core material is prepared from at least one of totarol, paeonol, honokiol, capryloyl glycine, glabridin, ascorbyl tetraisopalmitate, tetrahydrocurcumin or pterostilbene. Through a specific preparation method, the release speed of the core material is regulated and controlled by utilizing the reaction of lipase and the wall material, the slow release and controlled release effects are achieved, and industrial production is easy.

This invention belongs to the field of pharmaceutical formulation technology, and particularly relates to a pharmaceutical formulation for inhibiting esophageal squamous cell carcinoma metastasis and its preparation method. The preparation method of the pharmaceutical formulation for inhibiting esophageal squamous cell carcinoma metastasis includes the following steps: S1. Dissolving paclitaxel, cyperene, and a glyceryl stearate derivative in an organic solvent to obtain an oil phase; S2. Dissolving soybean lecithin and Tween 80 in water to obtain an aqueous phase; S3. Mixing the oil phase and the aqueous phase at 70-75°C, stirring to emulsify, cooling to room temperature, and freeze-drying to obtain the final product. This invention loads paclitaxel and cyperene into a nanodelivery system, constructing a pharmaceutical formulation that can both enhance antitumor effects and achieve precise and efficient mucosal delivery via oral administration, which has significant clinical significance and application prospects.

The invention relates to a flavor beverage capable of improving sleep and a preparation method thereof. Every 50ml of the flavored beverage comprises the following raw materials: a functional agent, a sweetening agent, an acidulant, a stabilizing agent and a solvent, the functional agent is prepared from 100 to 150 mg of gamma-aminobutyric acid, 2.5 to 3.5 g of resistant dextrin, 8 to 12 mg of long pepper extract powder, 6 to 10 mg of ginger extract powder, 12 to 18 mg of EGCG, 0.6 to 1.0 mg of L-phenylalanine compound, 3.0 to 4.5 mg of vitamin B6 and 1.5 to 2.25 mg of vitamin B2; the sweetening agent is prepared from 2.0 to 3.0 g of high fructose corn syrup, 0.4 to 0.6 g of fructose, 2.5 to 3.5 mg of acesulfame potassium and 1.2 to 1.8 mg of aspartame; the sour agent is prepared from 25 to 35 mg of vitamin C, 20 to 30 mg of citric acid and 3 to 5 ml of natural flavor extracting solution; the stabilizing agent is prepared from 5.0 to 7.0 mg of xanthan gum and 4.0 to 6.0 mg of glycerin monostearate; the solvent is purified water, and the total volume is 50ml; wherein the purity of the gamma-aminobutyric acid is greater than or equal to 99%, the piperine content in the long pepper extract powder is greater than or equal to 5%, and the gingerol content in the ginger extract powder is greater than or equal to 1%. The flavor beverage capable of improving sleep provided by the invention can mildly help sleep, and is high in bioavailability, healthy in taste, strong in stability, free of melatonin dependence and easy in mass production.