32 results about "Transepidermal water loss" patented technology

The invention relates to a method and a process of determining individual skin structure and function at a point in time for the purpose of determining and formulating skin care products that remedy the deficiencies observed in the skin. Objective and repeatable dermal biometric instrumentation techniques can be used to measure skin moisture content, sebum content, firmness and elasticity properties, skin thickness, transepidermal water loss, skin pH and to perform a photo analysis of the face with UV and visible light. By customizing the skin care products, the individually added active ingredients can be controlled, the diluents can be modified, dermal penetration rates can be controlled, the surfactant systems can be adjusted, and the stability of the product can be controlled. To prevent the loss of active materials in the product, the skin care product is manufactured for an individual consumer and is only sold in a quantity of a three months supply. Additionally, a variety of ingredients can be combined that a mass produced product cannot contain due to stability/compatibility issues. This invention overcomes the limitations in formulating skin products for the mass market by providing a product designed with objective biometric data and created for the specific clinical condition of an individual's skin.

The invention belongs to the field of cosmetics, and relates to a moisturizing technology in skin care products, namely a 24-hour moist three-layer moisturizing and repairing system. The skin care product provided by the invention is characterized in that kelp extractive, deep ocean water, pansy extractive and a water catching factor form a three-layer moisturizing and repairing system; the kelp extractive contains a plurality of minerals, saccharides and amino acid and has the moisturizing effect of reinforcing surface water locking of skin; the pansy extractive promotes synthesis of aquaporins in cell membranes, improves water circulation of dermis and promotes water to transfer from dermis to cuticle; silicon and manganese elements in the deep ocean water can reduce transepidermal water loss and are cooperative to achieve the effect of activating water deeply; and the water catching factor ensures that skin has the moisturizing effect of catching water outside. By means of the three-layer moisturizing and repairing system including surface water locking, water activating deeply and water catching outside, the skin care product provided by the invention can bring an intelligent lasting moisturizing technology to skin, so that bright, smooth, transparent and moist skin is brought.

The invention relates to a composition preferably for topical application in the form of a water-in-oil emulsion containing at least one emulsifying silicone elastomer and at least one semi-crystalline polymer. The invention also relates to the use of the composition according to the invention for skincare, and in particular for nourishing the skin, preventing transepidermal water loss and protecting the skin.

A method for measuring the rate of transepidermal water loss TEWL using a device for measuring TEWL which comprises:

(a) a measurement chamber with a single opening at one end, which opening is adapted to be placed against a test surface of skin;

(b) means to measure the density of water vapour within the measurement chamber; and

(c) an air agitating means positioned within the measurement chamber;

which method comprises:

(i) purging the measurement chamber of the device;

(ii) placing the open end of the measurement chamber against a test surface of skin;

(iii) measuring the rate of change of the density of water vapour within the measurement chamber; and

(iv) operating the agitating means whilst measuring changes of the density of water vapour within the measurement chamber to near uniformly mix water vapour from the test surface and air trapped in the measurement chamber.

The invention provides a radix lithospermi ointment and a preparation method thereof. Raw materials of the radix lithospermi ointment mainly comprise sesame seed oil, a radix lithospermi extract, dextrin palmitate and glyceryl behenate/eicosanoate. The invention also provides a corresponding preparation method. The radix lithospermi ointment prepared by adopting the formula and the preparation method has the effects of supplementing water, moisturizing, balancing oil grease and a pH value, promoting micro-circulation of blood of face skin, removing speckles, repairing skin and resisting allergy. Compared with the prior art, the radix lithospermi ointment disclosed by the invention has the advantages of comprehensive functions and obvious effect; after the radix lithospermi ointment provided by the invention is used, a moisture content MMV value of the skin, a trans-epidermal water loss (TEWL) value, a pH value of the skin and a blood perfusion value of a trial subject are all obviouslyimproved.

The present invention provides an externally applied composition capable of enhancing a stimulatory effect of an essential oil on IGF-1 secretion, the composition including (A) essential oil; and (B) at least one member selected from the group consisting of purine substances and salts thereof. Further, the present invention provides an externally applied composition capable of increasing the stratum corneum water content of the skin and maintaining transepidermal water loss at an appropriate level.

The invention relates to a nourishing and repairing lotion and a preparation method therefor, and belongs to the technical field of skin care products. The nourishing and repairing lotion comprises the following components in mass percentage: 1%-10% of hydrogenated polyisobutene, 0.5%-3% of emulsifier, 0.2%-5% of thickener, 0.1%-2% tocopheryl acetate, 0.1%-5% of ceramide compound liquid, 0.01%-2%of sodium hyaluronate, 0.01%-1% of glucan, 0.1%-3% of compound botanical whitening agent, 4%-6.5% of stabilizer and the balance water. The nourishing and repairing lotion can reduce redness and transepidermal water losses, plays a role of enhancing a skin barrier and helping dryness of damaged skin relieved, can further play a role of preventing aging, repairing the skin and reducing face dullness, maintains water and oil balance, forms a natural skin protective barrier for the skin, makes the skin tender and white and moisturized from the inside out, and reduces generation of skin melanin.

The invention relates to the technical field of cosmetics, in particular to moisturizing cream containing black algin and a preparation method and application of the moisturizing cream. The moisturizing cream containing black algin comprises an A phase, a B phase and a C phase, wherein the B phase comprises the following components in parts by weight of 1-8 parts of glycerine, 1-8 parts of butanediol, 0.01-0.5 part of ethylenediaminetetraacetic acid disodium salt, 0.5-1 part of a preservative, 1-5 parts of 1,2-pentanediol, 0.1-0.5 part of triethanolamine, 0.1-0.5 part of carbomer, 1-10 parts of black algin, 0.5-2 parts of ectoin and 60-80 parts of water. According to the moisturizing cream disclosed by the invention, the black algin is added, so that transepidermal water loss of skin can be reduced, moisture transportation is increased, and the moisture content of the skin can be effectively protected; besides, the ectoin is added for cooperation, so that damaged cell repair of the skin can be promoted, moisture of skin cuticle is increased, sodium pyrrolidone carboxylate absorbs moisture from air actively, and the absorbed moisture is closely combined with skin cells, so that themoisturizing properties of the products are strengthened, long-acting moisturizing effects can be achieved, and consumers can obtain better use experience.

The invention relates to the technical field of external preparations for skin, in particular to a composition, a preparation method thereof and an anti-aging cosmetic. The composition provided by the invention comprises the following components in percentage by mass: 25%-35% of a component A and 65%-75% of a component B. The component A comprises a spanishneedles herb plant extract, and the component B comprises a Concha Margaritiferallsta fermentation product. The composition disclosed by the invention has excellent fibroblast proliferation promoting activity and excellent anti-initial aging effect through coordination and cooperation of all the components. The anti-aging cosmetic prepared from the composition disclosed by the invention has a very good anti-aging effect, and after the anti-aging cosmetic is used, skin wrinkles can be remarkably reduced, the moisture content of a skin cuticle can be increased, rough skin can be reduced, the skin can be smoothed, the skin elasticity can be increased, and transepidermal water loss can be reduced.

An apparatus for estimating a skin barrier function or transepidermal water loss of an object may include a spectrum acquisition assembly configured to obtain a Raman spectrum of the object, and a processor configured to extract one or more Type-1 Raman band spectra related to lipids from the obtained Rama spectrum; extract one or more Type-2 Raman band spectra related to lipids and proteins from the obtained Raman spectrum; extract respective features of each of the extracted one or more Type-1 Raman band spectra and the extracted one or more Type-2 Raman band spectra; and estimate the skin barrier function or the transepidermal rater loss of the object based on the extracted features.

A method of producing Klotho protein includes preparing a Klotho plasmid DNA vector, culturing cells, transfecting the cells with the Klotho plasmid DNA vector in a cell culture medium, growing the transfected cells, and harvesting the cell culture supernatant by removing the transfected cells. The Klotho plasmid DNA vector has a mammalian selection marker and a Klotho open reading frame. The cells are primary fibroblast cells and/or mesenchymal stromal cells. A method of manufacturing a cosmetic composition includes combining Klotho protein or the cell culture supernatant with a cosmetically acceptable vehicle. A method of treating a patient to improve the condition and appearance of aging skin includes topically administering the cosmetic composition to the patient. By upregulating the Klotho gene in vitro and incorporating the Klotho protein and growth factors into a composition, transepidermal water loss, skin atrophy, and free radical damage to the skin may be addressed.

A skin function-improving composition for oral ingestion, which contains a milk-fat globule membrane. The composition is inexpensive, is highly safe, can be ingested orally, and has an activity of improving the dry condition of the skin so as to moisturize the skin. In particular, the milk-fat globule membrane is obtained from buttermilk or a processed product thereof. In particular, the composition has an activity of reducing transepidermal water loss or an activity of suppressing epidermal thickness. The composition can be ingested in the form of a food or beverage.

The invention provides air-dried preserved pork seasoned with a soy sauce and a making method of the air-dried preserved pork seasoned with the soy sauce. The making method comprises the following steps of selecting raw materials, performing trimming, performing cutting into strips, performing cleaning, performing vacuum rolling and kneading, preparing preserving liquid, performing preserving andair-drying, performing four-stage fumigation, performing cooling and performing packaging. According to the making method disclosed by the invention, a four-stage fumigation technology is adopted, andbefore formal fumigation, a preheating course and a drying course are additionally set, so that through the four-stage fumigation technology, the water migration rate in meat can be effectively increased; the situation that the vaporization rate of surface water in the roasting course of the preserved pork seasoned with a soy sauce is higher than the internal water diffusion rate is avoided, andinternal water cannot be complemented timely to the surfaces, so that the surface skins are dehydrated fast to form films and water transfer and transmission are further impeded is avoided; and the problem that the surface skins of the air-dried preserved pork seasoned with a soy sauce are dry, hard and crusted is solved. According to the air-dried preserved pork seasoned with a soy sauce disclosed by the invention, before preserving, the vacuum rolling and kneading operation is additionally set, and through rolling and kneading, meat blocks are subjected to mechanical treatment, so that protein extraction and protein movement towards the surfaces of the meat blocks are promoted, and the tenderness of meat is improved; and rolling and kneading influence the network structure of myofibril protein, so that after meat strips are loosened, the stickiness and the water retention property are increased, and performing of the subsequent preserving course is facilitated.

A cosmetic composition to prevent and/or ameliorate skin aging and applications thereof are provided in the present disclosure and the cosmetic composition comprises cyclic phosphatidic acid and citrus flavonoids which is hesperidin and/or hesperetin wherein the preventing and/or ameliorating skin aging include, without limitation, promoting moisture retention of stratum corneum, promoting skin elasticity, increasing presence or elasticity of collagens and elastins in fibroblasts, increasing transfers of fibroblasts, promoting anti-oxidation, increasing generation of hyaluronic acid, alleviating wrinkles and skin textures, moderating melanin, reducing skin oil and preventing transepidermal water losses.

The invention concerns novel compositions, and their use in the management of conditions associated with a defective or disrupted skin barrier in humans and animals. In particular, the invention relates to a colloid system resembling a cream with improved barrier properties. The invention may inter alia be used to diminish transepidermal water loss.

A transepidermal water loss measurement device includes a cylindrical closed chamber having a closed end and an open end to come into contact with the skin at a position at which a rate of water loss is to be measured and a transepidermal water loss measurement unit that measures a rate of transepidermal water loss of the skin by detecting levels of humidity and changes in humidity level in the closed chamber.

The invention discloses a traditional Chinese medicine composition with a moisturizing effect as well as an extract and application of the traditional Chinese medicine composition. According to the traditional Chinese medicine composition with the moisturizing effect as well as the extract and the application of the traditional Chinese medicine composition, radix peucedani, fructus cnidii, herba epimedii, polygala tenuifolia, bighead atractylodes rhizome and liquorice are combined together according to the compatibility of traditional Chinese medicine formulation to obtain the extract, the extract can be prepared into a product with a skin moisturizing effect and can relieve and moisten the skin, increase the moisture value of the skin, improve the skin barrier function and reduce transepidermal water loss, the problems of dry skin, chapped skin, desquamation, peeling, sensitivity, dull skin color, premature aging and the like are solved or improved, and the skin is kept in a comfortable, moist, soft and smooth good state.

The present invention is drawn to a process for providing emolliency to the skin using a series so called “silicone spider esters”. These esters are derived from poly-hydroxy functional compounds sequentially reacted with ethylene oxide or propylene oxide, followed by the reaction of the alkoxylate with fatty acid. The resulting products are called silicone spider esters because they resemble the spider, wherein appendages are alkoxylated esters. The restrictions this orientation imposes on rotation allows for the preparation of polar esters that have little or no water solubility, and provide both moisturization to the skin and emolliency by reducing transepidermal water loss.