387 results about "Skin barrier function" patented technology

A skin barrier lotion for protection against contact with irritants comprises: about 5 to 15 percent by weight of a long-chain fatty acid; about 1 to 5 percent by weight of a long-chain fatty alcohol; about 1 to 10 percent by weight of a hydrocarbon oil; about 1 to 30 percent by weight of a silicone skin protectant; about 0.5 to about 5 percent by weight of an alkanolamine; about 0.5 to about 5 percent by weight of a humectant; about 0.5 to about 10 percent by weight of an inorganic skin protectant; about 0.5 to 15 weight percent of a preservative; and about 50 to 90 percent by weight water. Optionally, the lotion will also contain up to about 5 percent by weight of a fragrance, odor neutralizer or a mixture thereof.

The present invention relates to a composition used as a vehicle for percutaneous absorption of Pharmaceutical and Cosmaceutical active agents that comprises Dimethiconol (hydroxyl-terminated polydimethydimethylsiloxane), dimethicone-350 (polydimethylsiloxane-350), cyclomethicone-5 nf (decamethylcyclopentasiloxane), alkymeth siloxane copolyol-lauryl peg / ppg 18 / 18 methicone (alkymethyl siloxane copolyol), cyclopentasiloxane and dimethicone Crosspolymer (silicone elastomer and decamethylcyclopentasiloxane), stearoxytrimethylsilane and stearyl alcohol (silicone wax), and deionized water. This composition serves several key applications: (1) it is a vehicle for percutaneous absorption of Pharmaceutical and Cosmaceutical active agents; (2) it acts as a method for utilizing other compositions in the treatment of inflammatory conditions of the skin including, but by no means limited to, atopic dermatitis (eczema), allergic contact dermatitis, seborrheic dermatitits, psoriasis, xerosis and atopia; (3) it is a treatment of inflammatory conditions of mucosae; (4) it relates to other compositions and methods for protecting and enhancing the barrier function of the skin.

Absorbent articles having enhanced absorption of bodily exudates are disclosed. The absorbent articles comprise a bodily exudate modifying agent and a skin care formulation. The bodily exudate modifying agent is capable of reducing the viscosity of bodily exudates such as feces and menses. The skin care formulation comprises a bodily exudate modifying agent neutralizer to neutralize the possible negative effects on skin barrier function caused by the bodily exudate modifying agents coming into direct contact with the wearer's skin.

Compositions, kits and methods are provided for restoring skin barrier function to skin exposed to environmental elements and / or in a pathological condition. In general, divalent cations such as calcium ions and / or magnesium ions are included in a physiologically acceptable medium. In some embodiments, divalent cations are balanced with monovalent cations such as sodium and potassium ions at appropriate ratios in order to maintain the homeostasis of skin barrier. The compositions, kits and methods can be used as cosmetics, cosmeceuticals or pharmaceuticals for improving skin condition, and preventing or treating dermatological diseases and skin disorders.

Compositions and methods of treating conditions of compromised skin barrier function are described.

The invention relates to recombinant human-derived collagen series products for skin barrier function injuries or haemorrhoids, in particular to a medical recombinant human-derived collagen function dressing (spray type), medical skin collagen repair function dressing, medical recombinant human-derived collagen function dressing (gel type) and a collagen trauma hemostatic material (hemorrhoids type). The product provided by the invention has an obvious curative effect on skin barrier function injuries or haemorrhoids, and has popularization and application value.

The invention relates to a plant active component composition with slow anti-allergic action. The plant active component composition is mainly prepared from natural plant active components: 0.1-5wt% of glycyrrhetinic acid, 0.05-1wt% of apigenin, 0.05-1% of table gallic catechin gallic acid ester, 0.1-3wt% of asiaticoside, 0.1-5wt% of baicalin and 0.1-10wt% of fucus serratus extract. The composition is used for preparing cosmetics or personal care products with a plurality of effects of resisting skin allergy, diminishing inflammation, relieving itching, resisting oxidation, moisturizing and the like. The composition is safe and free of toxic and side effects, and can be compounded with a plurality of components, sensitive skin and dry skin are effectively improved, and the barrier function of the skin is reinforced.

The invention relates to a moisturizing composition, and a preparation method and application thereof, which belong to the field of cosmetics. The moisturizing composition is prepared from the following components in parts by weight: 1.0 to 5.0 parts of sodium hyaluronate, 2.0 to 10.0 parts of carboxymethyl deacetyl chitosan, 30.0 to 60.0 parts of dendrobium officinale extract, and 25.0 to 67.0 parts of deionized water. The moisturizing composition can well form a netted natural biomimetic membrane with skin, the sodium hyaluronate performs the water supplementation and moisturizing in the biomimetic membrane, the carboxymethyl deacetyl chitosan forms a biomimetic sterile membrane, so that natural moisturizing factors such as the sodium hyaluronate can be effectively locked, the water loss rate is decreased; and the dendrobium officinale polysaccharide is combined with the natural biomimetic sterile membrane, so that the moisturizing lasting property after long-term use can be further improved, the restoration effect is improved, and the dryness and allergy problems of the skin can be fundamentally solved. The moisturizing composition has multidimensional efficacy such as moisturizing function, restoration function and skin barrier increasing function.

The invention discloses a whitening composition and cream thereof. The whitening cream contains a whitening composition which is prepared from nicotinamide, arbutin, citrus peel extractives, tea extractives, scutellaria root extractives, cucumber extractives, apple extractives and the like, wherein the nicotinamide can enhance the skin barrier function, and has the effects of whitening the skin and resisting aging and acnes; the arbutin can inhibit activity of tyrosinase to achieve the whitening effect, and can protect the skin against free radical damage; the citrus peel extractives can enhance the skin brightness, lower percutaneous water loss and enhance the skin moisturizing and barrier functions; due to the synergistic effect of the tea extractives, the scutellaria root extractives, the cucumber extractives and the apple extractives, the effects of whitening, skin tendering and moisturizing are enhanced; the whitening composition is used in whitening skin care products such as a whitening cream product, dark skin and primary spots on the skin can be remarkably improved, the deposited stains and coloring matter accumulated over a long period can be faded and relieved, and the whitening effect is obvious.

The invention belongs to the technical field of daily care products and discloses a facial mask with the functions of improving skin barrier and delaying senescence and a preparation method thereof. The facial mask comprises the following components in percentage by weight: 0.05-4 percent of macromolecule hyaluronic acid, 0.1-3 percent of middle molecule hyaluronic acid, 0.1-5 percent of micromolecule hyaluronic acid, 0.05-3 percent of oligomeric hyaluronic acid, 0.5-6 percent of grape seed extract, 0.5-6 percent of purslane extract, 2-12 percent of hydroxyethyl urea, 1-6 percent of sodium pyrrolidonecarboxylate, 0.1-1 percent of allantoin, 2-12 percent of butanediol, 0.05-0.3 percent of thickening agent and the balance of deionized water. According to the facial mask disclosed by the invention, by reasonably combining natural compounds with plant extracts, the synergistic effect is realized, and the functions of better improving the skin barrier and delaying the senescence are achieved.

Compositions, kits and methods are provided for restoring skin barrier function to skin exposed to environmental elements and / or in a pathological condition. In general, divalent cations such as calcium ions and / or magnesium ions are included in a physiologically acceptable medium. In some embodiments, divalent cations are balanced with monovalent cations such as sodium and potassium ions at appropriate ratios in order to maintain the homeostasis of skin barrier. The compositions, kits and methods can be used as cosmetics, cosmeceuticals or pharmaceuticals for improving skin condition, and preventing or treating dermatological diseases and skin disorders.

The disclosure relates to topical compositions and methods comprising whole, non-viable Micrococcaceae cells, wherein the cells have been processed to kill the cells while minimizing lysis. The topical compositions and methods are useful for decreasing skin inflammation and improving skin barrier function.

The present invention provides compositions containing a mixture of cholesterol sulfate and an exfoliant. The exfoliant can be N-acetyl-D-glucosamine, N-acetylgalactosamine, or a combination thereof. The combination of cholesterol sulfate with the exfoliant surprisingly enhances the skin barrier even though the activity of each of the components is opposite the other. In addition, because of the ability to enhance or repair the skin barrier function, methods of maintaining or improving a healthy skin barrier are included in the present invention by apply to the skin an effective amount of the mixture of cholesterol sulfate with the exfoliant. The mixture can also be useful in treating or preventing damage to the skin, where the damage is caused by a comprised skin barrier function. As a result of improved skin barrier function, the appearance of lines and wrinkles is generally reduced; rough and dry skin conditions are also improved.

A wipe article comprising a composition comprising omega-6 fatty acid. A method of improving skin barrier function of semi-occluded skin comprising the step of contacting the semi-occluded skin with a wipe comprising an omega-6 fatty acid.

The invention discloses an anti-inflammation and allergy-relieving repair composition and a preparation method and an application thereof. The composition consists of a cactus extract, an oat bran extract, a sophorae flavescentis extract, an ophiopogon japonicus root extract, a peony root extract, a scutellaria baicalensis root extract, butanediol, pentanediol and water. The preparation method comprises the following steps: 1) preparing a sophorae flavescentis extract solution; 2) carrying out super-high pressure homogenization of the cactus extract, the oat bran extract, the ophiopogon japonicus root extract, the peony root extract, the scutellaria baicalensis root extract, butanediol and pentanediol to obtain a plant extract mixed solution; and 3) carrying out mixing, super-high pressurehomogenization and filtration of the plant extract mixed solution and the sophorae flavescentis extract solution. The anti-inflammation and allergy-relieving repair composition has anti-inflammatory,anti-allergic and analgesic effects, can enhance skin barrier function, enhances the skin self-protection ability, effectively repairs inflammatory skin, especially skins suffered from hormone-dependent dermatitis and cannot produce drug resistance, dependence and side effects after being used for a long time.

The invention relates to an anti-allergic moisturizing composition with a function of repairing skin barrier and an external preparation thereof. The main component of the anti-allergic moisturizing composition with the function of repairing skin barrier comprises the following components of repairing skin barrier in parts by weight: 3-10 parts of a grape seed extract and 1-5 parts of nicotinamide, the following components of natural extracts anti-allergic itch-relieving components: 0.5-1 part of dipotassium glycyrrhizinate, 1-2 parts of a chamomile extract and 0.25-1 part of a radix sophorae flavescentis extract, and the following moisturizing nutritional components: 1-3 parts of polydimethylsiloxane, 3-5 parts of glycerinum, 4-8 parts of propylene glycol, 4-8 parts of butanediol, 2-5 parts of sodium hyaluronate and 0.5-2 parts of allantoin. The components are combined to prepare an external emulsion preparation which has the function of repairing skin barrier and anti-allergic, moisturizing and nutritional performances.

Methods and compositions for cell regeneration and decreased irritation of mammalian skin cells are provided, wherein the compositions include a synergistic combination of two or more oligopeptides. The compositions may advantageously be applied to mammalian skin to effect a regeneration of skin cells and to effect a reduction in inflammation and redness experienced by the skin. Skin cleansing and sanitizing compositions are provided that include at least one oligopeptide, wherein the compositions have reduced irritancy potential.

The invention provides a cosmetic product which has a good texture and allows full expression of the inherent functions of ceramide as an intercellular lipid, such as skin barrier function and hair protection effect, as well as nanoparticles for cosmetics and powder for cosmetics which may be used in the above cosmetic product, exhibit good skin barrier function and hair protection effect, and are easy to incorporate into the above cosmetic product. The cosmetic product, the nanoparticles, and the powder for cosmetics according to the present invention contain a polymer obtained by polymerization of a monomer material containing a glycerol(meth)acrylate monomer represented by the formula (1): (R1: —H, —CH3; R2: —(CH2)n-; n is an integer of 1 to 4).

Provided is a new bionic skin material with multiple functions and a high efficacy. With a compound microporous fibre net structure, the material imitates a skin barrier function, has anti-fouling properties, hygroscopic properties, moisture retention properties, air permeability, flexibility and adhesiveness, and can effectively absorb wound exudate and residues for rapid painless autolysis and debridement, ensure sufficient drainage by bidirectional regulation, maintain a semi-closed, local physiological wet environment favorable for the reparative metabolism and physiological healing of a wound, inhibit inflammation, reduce exudation, benefit the response inside and outside of cells, promote the migration of fibroblasts and epithelial cells of the body itself and the regeneration of granulation tissue and epithelial cells of the wound, accelerate the physiological healing and recovery of the wound, and reduce recurrences. It has been clinically proved that the dressing material can accelerate the healing of acute skin injuries and chronic ulcer wounds, achieve a high healing quality, avoid or reduce traumatic skin grafting to the greatest extent, reduce the pain of patients and the production of scars, and restore the physiological function and appearance of the body.

The invention discloses an anti-aging and wrinkle-removing composition. The anti-aging and wrinkle-removing composition is prepared from the following components in percentage by mass: 3-10% of hydrolyzed collagen, 3-15% of polypeptide, 0.4-10% of humectant, 1-3% of compound amino acid, 0.5-1% of ceramide-3, 3-10% of polyhydric alcohol, 1-10% of antioxidant, 0.1-1% of preservative, 0.02-1% of chelating agent, 0.1-5% of anti-allergic agent and the balance deionized water. According to the anti-aging and wrinkle-removing composition, the hydrolyzed collagen, the polypeptide, the humectant, the compound amino acid, the ceramide 3, the polyhydric alcohol and the antioxidant are scientifically proportioned according to the structural characteristics of skin and the physiological function requirements of the skin, so that the anti-aging and wrinkle-removing composition can be used for removing wrinkles instantly and removing wrinkles for a long time; and after the anti-aging and wrinkle-removing composition is used for a long time, the effects of reconstructing a skin cell collagen network, deeply removing wrinkles and resisting aging, plumping the skin, improving the water content of epidermal cells, enhancing the skin barrier function, brightening the skin, increasing the skin elasticity and brightening the skin color are achieved.

The present invention provides methods for treating, preventing or ameliorating skin infections, including bacterial and viral infections. In certain embodiments, the invention provides methods to reduce skin infection in a patient with atopic dermatitis (AD). Also provided are methods for improving skin barrier function, and methods for reducing the risk of inflammation due to microbial infection in a patient in need thereof. The methods of the present invention comprise administering to a patient in need thereof a pharmaceutical composition comprising an interleukin-4 receptor (IL-4R) antagonist such as an anti-IL-4R antibody.

The invention discloses essential oil for preventing and repairing skin barrier injury. The essential oil comprises the following components in percent by weight: 1.0 to 50 percent of camellia seed oil, 2.0 to 20 percent of plant oil, 0.5 to 5 percent of a relieving agent, 0.05 to 5 percent of a stabilizer, and the balance of synthetic oil. The essential oil contains rich various functional components; as all the components are harmonious with one another and synergistically affected, the essential oil can prevent skin barrier injury, and promote the repair process of skin barrier injury, andhas a good anti-allergy effect on sensitive skin with the disordered skin barrier function; in addition, the essential oil dost not contain emulgators or essence components, thereby avoiding an excessburden on skin.

The invention relates to a skin care composition with sunscreen repair effect and an application and a preparation method thereof. The composition comprises the following components in parts by weight: 0.1-3 pbw plant sensitizer; 0.01 to 1.0 pbw of codogen; 0.1 to 1.0 pbw of hydrolyzed yeast protein; 0.01 to 0.5 pbw of green algae extract; 0.01 to 0.1 pbw of hamamelis extract; 0.01 to 0.1 pbw of tremella polysaccharide; 0.1 to 1.0 pbw of oat glucan; 0.1 to 1.0 pbw of allantoin; 0.01 to 1.0 pbw of compound ceramide; 0.01 to 1.0 pbw of sunflower unsaponifiable matter; 1.0-10.0 pbw of glycerol; 1.0-10.0 pbw of methyl propylene glycol; 0.01-1.0 pbw of sodium hyaluronate; 0.1-10.0 pbw of betaine and 0.1-1.0 pbw of panthenol. According to the skin care composition with sunscreen repair effect and the application and the preparation method thereof, the synergistic effect among the components is fully exerted by utilizing different medicinal mechanisms of the components, so that the obtained composition can enhance the cell self-repairing function, promote the division and growth of skin cells, resist ultraviolet damage and repair the skin barrier function.

The invention discloses a self-antiseptic hippophae rhamnoides restoring lip protector, and a preparation method thereof. The self-antiseptic hippophae rhamnoides restoring lip protector is composed of 50 to 90 parts of plant oil, 5 to 35 parts of waxiness, 0.5 to 30 parts of a plant extraction restoring agent, 0.1 to 5 parts of plant essential oil, and 0.05 to 5 parts of an antioxidant. The self-antiseptic hippophae rhamnoides restoring lip protector is prepared from natural food-grade raw materials, is safe and nontoxic, is unique in formula, is rich in the plant extraction restoring agent, and is capable of avoiding lip cracking, skin peeling, and generation of lip prints, promoting metabolism of delicate skin, and providing lip with water gloss. The self-antiseptic hippophae rhamnoides restoring lip protector is self antiseptic and refreshing, and is capable of providing moisture, comforting skin, and rebuilding skin barrier functions.

The invention discloses a two-in-one nourishing and moisturizing bath composition, which comprises the following ingredients (by weight): 40-70% of an oily component, 15-40% of a surfactant, 1-10% ofan emollient, 0.01-5% of a nutritional component and 0.01-5% of a stabilizer. The composition of the invention is mild, has low level of irritation, has good foam, is nourishing and moisturizing, is moisturizing and soft during bathing, and will not have sticky feeling. Through reasonable matching of selected natural oil, MIPA-laureth sulfate and lauryl polyoxyethylene (4), bathing sticky feelingof an oily bath product is improved. The selected sunflower seed oil and caprylic / capric triglyceride have nourishing and moisturizing, antioxidation and skin repairing and barrier functions. Througha reasonable proportion of the emollient, irritation caused by anionic and nonionic surfactants used in the product is greatly reduced. A hydrophilic film is formed on the epidermis, thus greatly raising skin barrier function. With the protective film while cleaning and through lots of oil, the skin is provided with a nourishing and soft feeling.

The invention relates to a composition for balancing skin micro-ecology as well as a preparation method and application thereof. The composition for balancing the skin micro-ecology comprises a saccharomycetes ferment filtrate, a bifida ferment lysate, a lactobacillus ferment, trehalose and a saccharide isomeride. According to the composition disclosed by the invention, all the components are matched with one another and have a synergistic effect, so that the composition for balancing the skin micro-ecology can preserve moisture, improve the skin barrier function, promote the proliferation ofskin beneficial bacteria, inhibit harmful bacteria, repair Langerhans cells damaged by ultraviolet rays and enhance the ultraviolet immune function of the skin. A sunscreen lotion containing the composition for balancing the skin micro-ecology can effectively preserve moisture and repair ultraviolet injury, can reduce inflammatory spots, improve skin flaws and enhance skin gloss, and has a wide development prospect in the field of cosmetics.

Compositions, kits and methods are provided for restoring skin barrier function to skin exposed to environmental elements and / or in a pathological condition. In general, divalent cations such as calcium ions and / or magnesium ions are included in a physiologically acceptable medium. In some embodiments, divalent cations are balanced with monovalent cations such as sodium and potassium ions at appropriate ratios in order to maintain the homeostasis of skin barrier. The compositions, kits and methods can be used as cosmetics, cosmeceuticals or pharmaceuticals for improving skin condition, and preventing or treating dermatological diseases and skin disorders.

Disclosed is composite powder comprising infrared-ray blocking particles; and ultraviolet-ray blocking particles coated onto one surface of each of the infrared-ray blocking particles, and cosmetics composition using the same, wherein the composite powder using both the infrared-ray blocking particle and the ultraviolet-ray blocking particle enables to simultaneously block the infrared and ultraviolet rays. Thus, if the composite powder of the present invention is applied to the cosmetics, it is possible to minimize the rough wrinkles, irregular pigmentary deposits, loss of skin elasticity, disturbance of skin barrier function, skin damages such as cancer of the skin, and skin aging, and also to boost SPF (Sun Protection Factor) and PA (Protection Factor of UVA) of the related art sunscreen. Especially, the present invention uses the composite powder prepared by coating one surface of the infrared-ray blocking particle with the ultraviolet-ray blocking particles, instead of mixing powder prepared by simply mixing the infrared-ray blocking particle and the ultraviolet-ray blocking particle. That is, since the small-sized ultraviolet-ray blocking particles are coated onto and stably fixed into the surface of the infrared-ray blocking particle, it is possible to prevent aggregation of the ultraviolet-ray blocking particles, thereby preventing deterioration in uniformity of adhesion to the skin, and deterioration of the ultraviolet-ray blocking efficiency.

This invention relates to compositions and methods useful in treating dermatological disorders. In particular, the methods include applying a composition that includes a reactive reinforcing component; and a cross-linking component; in which the cross-linking component facilitates in situ cross-linking of the reactive reinforcing component, such that a film is formed on skin, thereby treating the dermatological disorder.