87 results about "Calendula" patented technology

The invention provides a pharmaceutical composition for preventing and treating gingival atrophy and a preparation method and application thereof, and belongs to the technical field of biological medicine. The composition contains finless eel peptide, skipjack elastin peptide, quinoa rice extract, gleditsia sinensis rice extract, calendula extract, chamomile extract, chitosan, peach gum, hydroxyapatite and the like, and the finless eel peptide, the skipjack elastin peptide, the quinoa rice extract and the gleditsia sinensis rice extract are specific enzymatic hydrolysates. The monopterus albus peptide, the skipjack elastin peptide, the quinoa rice extract and the gleditsia sinensis rice extract jointly promote repair and regeneration of gingival tissues. The calendula extract, the chamomile extract and the chitosan have anti-inflammatory and antibacterial effects, so that gingival inflammation is relieved, and bacterial infection is prevented. And the chitosan and the calendula extract can accelerate the repair of damaged gingival tissues. The monopterus albus peptide, the skipjack elastin peptide and the hydroxyapatite are matched for use to jointly maintain the normal structure and function of gingiva. All the components have a synergistic effect, so that gingival atrophy can be effectively prevented and improved.

The invention discloses a calendula double-bacterium fermentation product as well as a preparation method and application thereof, and relates to the technical field of plant fermentation. The preparation method of the calendula double-bacterium fermentation product disclosed by the invention comprises the following steps: carrying out primary fermentation by using lactobacillus plantarum, then carrying out secondary fermentation by using saccharomyces cerevisiae, and carrying out sterilization and filtration treatment on the calendula fermentation liquid subjected to secondary fermentation, so as to obtain the calendula fermentation liquid. The calendula fermentation liquor is subjected to combined fermentation through lactobacillus plantarum and saccharomyces cerevisiae, and the content of polyphenol and flavone in the calendula double-bacterium fermentation product is remarkably increased. Meanwhile, the calendula double-bacterium fermentation product has the effects of preserving moisture, resisting oxidation, relieving and controlling oil, and has a wide application prospect in the field of cosmetics.

The invention relates to a preparation method of a calendula fermentation product. The preparation method comprises the step of fermenting calendula with saccharomycetes and lactobacillus in sequence. According to the invention, the calendula is subjected to secondary fermentation by adopting a method of firstly fermenting by using the saccharomycetes and then fermenting by using the lactobacillus, and the calendula is fermented through the synergistic effect of the two bacteria, so that the obtained calendula fermented product has the comprehensive effects of moisturizing, repairing and relieving.

The invention provides eye protection liquid for improving eye microcirculation and a preparation method thereof, and belongs to the technical field of medical configuration products. The composition comprises the following components: surface-modified magnetic nanoparticles, a calendula extract, a fermented dogwood extract, xanthophyll, taurine, sodium hyaluronate, hydrolyzed sodium hyaluronate, soya bean lecithin, borneol and fermented vegetable oil. The efficiency of active ingredients is improved through a double-fermentation technology, magnetic targeting and multi-channel compounding are combined, and the preparation method has remarkable advantages in the field of improving periorbital microcirculation. The traditional Chinese medicine composition has an obvious relieving effect on asthenopia and dry skin around eyes; the components of the eye microcirculation eye protection liquid are mild, and adverse reactions such as allergy cannot be caused.

The invention discloses an anti-aging composition, a preparation method and application of the anti-aging composition in skin aging resistance, belongs to the technical field of cosmetics, and aims at solving the problems that in related technologies, anti-aging cosmetics are instable in functional components, and the skin aging resistance of transdermal absorbability and functional component combination needs to be further improved. The anti-aging composition is prepared from the following components in percentage by total weight of the composition: 10 to 20 percent of an anti-aging functional composition and 80 to 90 percent of an auxiliary material matrix, the composition with the anti-aging effect is prepared from the following main components: ascorbyl tetraisopalmitate, epigallocatechin gallate, hydroxytyrosol, a calendula extract, curcumin, resveratrol and glutathione. The anti-aging composition prepared by the invention has good stability, transdermal absorbability and capability of improving skin aging resistance.

The present invention provides a salmon mask with anti-inflammatory, anti-aging and repairing effects and a preparation method thereof, belonging to the field of cosmetic technology. The salmon mask includes the following components by weight: Phase A: 2-5 parts of aloe vera gel, 1-3 parts of sodium carrageenan, 2-4 parts of sodium alginate, 1-5 parts of konjac gum, 3-5 parts of glycerol and 85-95 parts of high-purity water; Phase B: 5-10 parts of polydeoxyribonucleotides, 10-25 parts of Centella asiatica extract, 10-25 parts of Portulaca oleracea extract, 5-15 parts of Calendula officinalis extract, 10-20 parts of hyaluronic acid, 2-5 parts of acetyl tetrapeptide-15, 1-3 parts of palmitoyl tetrapeptide-7, 1-3 parts of acetyl hexapeptide-8, 3-8 parts of conopeptide, 1-3 parts of snake venom tripeptide and 2-5 parts of pentapeptide-3. The present invention makes the obtained mask have better anti-inflammatory, moisturizing and repairing effects by selecting specific ingredients.

The invention relates to the technical field of functional fibers, and particularly discloses a chinlon BI fiber with an anti-allergy function prepared by using a molecular nest technology, which is prepared from the following raw materials in parts by weight: 100-300 parts of chinlon chips, 15-30 parts of molecular nests containing plant active ingredients and 1-7 parts of a dispersing agent, the molecular nest containing the plant active ingredients is obtained by loading a calendula extract, a liquorice extract and a green tea extract on sulfonated mesoporous silica, and the sulfonated mesoporous silica can stably adsorb the plant active ingredients, so that carbonization inactivation caused by high temperature of spinning due to direct addition of natural active ingredients is avoided; therefore, the chinlon BI fiber disclosed by the invention has an anti-allergy function, and is remarkable in antibacterial and antioxidant activity and wide in market application prospect.

The invention discloses a soothing and oil-controlling composition derived from natural plants and application thereof, and belongs to the technical field of daily cosmetics. The composition is formed by compounding an artemisia annua extract, a rehmannia root extract, a calendula extract and a pomelo fruit extract, and the four plant extracts have a synergistic effect, have the effects of repairing, relieving and controlling oil, and can be used for preparing a skin care product special for oil-sensitive skin. The composition provided by the invention can effectively solve the problems of external oil and internal dry, redness and sensitivity, grease accumulation and the like of oily sensitive skin, and meets multiple skin care requirements.

The invention relates to a skincare composition and microemulsion based on compound natural components of convalescent tomentosa and a preparation method of the skincare composition and the microemulsion. The skincare composition comprises the following extracts in parts by weight: 0.01-10 parts of a convalescent tomentosa extract, 1-6 parts of a calendula extract, 0.5-3 parts of a fucus extract and 0.2-2 parts of a myrrh resin extract. According to the scheme, firstly, through component optimization, a convalescent tomentosa extract is used as a main material, a calendula extract, a fucus extract and a myrrh resin extract are used as auxiliary materials, a composite plant synergistic matrix is constructed, and red skin relieving and rapid itching relieving are achieved through multi-target regulation and control; meanwhile, the technical improvement of an extraction method is combined, effective components of all the raw materials can be comprehensively extracted, the synergistic effect is achieved, and then preparation optimization is combined, so that application of the composition is facilitated.

The invention relates to the technical field of cosmetics, and discloses a high-efficiency mild depilation cosmetic and a preparation method thereof, and the raw materials of the depilation cosmetic comprise, by weight, 8-10% of bromelain; 10%-12% of a turmeric root extract; 9%-11% of a calendula extract; 6%-9% of an aloe extract; 4%-7% of a soybean extract; 7%-10% of calcium thioglycolate; 2%-5% of L-cysteine; 1%-3% of sodium bicarbonate; 3%-6% of green tea polyphenol; 2%-4% of a chamomile extract; 1%-3% of dipotassium glycyrrhizinate; 0.9%-2.3% of a peptide component; 0.5%-1% of rosmarinic acid; 1%-3% of vitamin E; 2%-4% of gluconic acid; 4%-5% of beewax; 5%-10% of an emulsifier; according to the invention, dipotassium glycyrrhizinate and the chamomile extract form a dual anti-allergy barrier, the physical protection effect of aloe polysaccharide is combined to reduce skin irritation, and the turmeric root extract and the peptide component prolong the hair follicle resting period and reduce the hair regeneration rate, so that the safer and more effective hair removal cosmetic is prepared.

The invention relates to calendula fermentation liquor, a preparation method thereof and application of the calendula fermentation liquor in antiperspirant cosmetics, and belongs to the technical field of plant fermentation and cosmetics. The preparation method of the calendula fermentation liquor provided by the invention comprises the following steps: 1) taking calendula powder as a fermentation substrate, inoculating bifidobacteria, and carrying out anaerobic fermentation to obtain the calendula fermentation liquor A; 2) inoculating saccharomycetes into the fermentation liquor A for aerobic fermentation to obtain calendula fermentation liquor B; and (3) carrying out wall-breaking homogenization treatment on the fermentation liquor B, and filtering by using a nano-membrane to obtain the calendula fermentation liquor. According to the calendula fermentation liquor, the sweating amount is reduced, meanwhile, the effect of inhibiting grease secretion can be improved, armpit sweating can generate peculiar smell along with grease secretion, therefore, the peculiar smell generated by grease secretion can be effectively reduced, and the calendula fermentation liquor has obvious advantages when being applied to antiperspirant cosmetics.

The invention relates to a composition containing anti-wrinkle lipidosome for cosmetic preparation and a preparation method of the composition, and belongs to the technical field of cosmetics. The invention discloses a composition containing anti-wrinkle lipidosome and a preparation method thereof. The composition comprises four plant extracts of purple coneflower, calendula officinalis, salvia officinalis and elderberry, and lipidosome consisting of lecithin, cholesterol, sphingomyelin and ascorbyl palmitate, and is supplemented with components such as a humectant and an emulsifier. According to the composition, through the synergistic effect of the plant extract and the lipidosome, the anti-wrinkle effect is enhanced, and the storage and illumination stability is improved; an extract structure is optimized by a compound fermentation process, and a liposome system is adapted; the components are safe and suitable for multiple skin types, the preparation process is compatible with industrial production, and the pain points that traditional anti-wrinkle products are poor in stability and insufficient in effect are solved.

The invention relates to a small molecule water-containing composition for preparing beauty water and a preparation method thereof, and belongs to the technical field of cosmetics, the composition comprises composite plant hydrolat, plant essential oil and an emulsifier; the composite plant hydrolat comprises calendula hydrolat, pawpaw hydrolat, tulip hydrolat, fructus amomi rotundus hydrolat, torreya grandis hydrolat, linden viburnum hydrolat, lignum dalbergiae odoriferae hydrolat and peony hydrolat; the plant essential oil comprises thyme oil. Most of the selected raw materials are plant hydrolats, crude plant hydrolat liquid is subjected to small molecule treatment, so that the plant hydrolat liquid is easier to absorb, more stable and more efficient, in addition, the finally selected raw materials have the effects of moisturizing, resisting oxidation and inhibiting bacteria, a good foundation is laid for moisturizing and enhancing the skin barrier function, the effects of resisting oxidation and preventing damage are achieved, and the skin care effect is achieved. The skin micro-ecology stability is maintained through bacteriostasis, the three effects are integrated, and the improvement and beautifying of the skin quality are realized.

The present invention discloses a pain relieving plaster preparation process and a filtration treatment system, and relates to the field of medical equipment, the pain relieving plaster comprises the following production raw materials by mass ratio (W / W%): 3.0-5.0% of menthol; 0.5 to 1.0 part of carbomer; 0.3 to 0.7 part of camphor; 0.5 to 0.9 part of triethanolamine; 23.0 to 29.0 parts of isopropyl alcohol; 0.2 to 0.3 part of an arnica flower extract; 4.0 to 5.0 parts of glycerol; 0.4 to 0.6 part of isopropyl myristate; 0.1 to 0.2 part of a calendula flower extract; 0.01 to 0.03 part of VE (Vitamin E) acetate; 0.1 to 0.2 part of melissa officinalis leaf extract; 0.005 to 0.015 part of aloe barbadensis leaf juice; 0.1 to 0.3 part of burdock extract; 0.4-0.6% of a tea leaf extract; 0.1-0.3 part of a paraguay tea leaf extract; 0.04 to 0.06 part of olibanum serratum extract; 0.05 to 0.15 part of a methyl methacrylate cross-linked polymer; 0.001 to 0.003 part of a pigment; and the rest is water. According to the invention, menthol is taken as a main active component for relieving pain and is matched with components such as skin-care grease, an ointment product with a pain-relieving effect is produced through a physical mixing process, and the quick-acting formula can deeply permeate and quickly dry and is wide in application range.

The present invention discloses a plant based industrial lubricant formulation that includes three major components. The first component includes at least one constituent such as ester of soyabean oil, ester of sesame oil, ester of corn oil, ester of caster oil, ester of canola, ester of safflower oil and the like. The second component includes at least one of the constituents including Sapindus mucorossi, neem oil and calendula oil. Further, the third component is a nanoparticle component which includes Zinc Sulfide nanoparticles, hexagonal boron nitrate nanoparticles and molebdenum disulfide nanoparticles. Also disclosed is a process for preparation of a plant based industrial lubricant of the present invention. This lubricant formulation has varied applications in various industries due to adjustable viscosities and flashpoints.

The invention discloses an eye care composition and an eye care solution, and belongs to the technical field of cosmetics, the eye care composition comprises hyaluronic acid substances, a Chinese herbaceous peony root extract and a calendula extract according to a mass ratio of 1: (0.5-8): (2-10); the sodium hyaluronate substances comprise a sodium hyaluronate cross-linked polymer, hydrolyzed sodium hyaluronate, acetylated sodium hyaluronate and sodium hyaluronate in a mass ratio of 1: (0.25-4): (0.25-4): (0.5-1). The eye care solution containing the eye care composition has excellent moisturizing and repairing effects, can effectively solve the problems of eye dryness and eye acerbity, relieves eye fatigue, and comprehensively improves the eye condition.

The invention relates to an ointment-containing adult diaper specially developed for adult patients suffering from urinary and fecal incontinence, comprising an ointment layer (1) containing zinc oxide, petrolatum, lanolin, aloe vera, panthenol, and vegetable oils (capric / caprylic triglyceride, stearyl alcohol, sweet almond oil, olive oil, calendula officinalis flower extract, hamamelis virginiana (witch hazel) extract), which protects the skin from irritation, moisturizes it, and provides a healing effect, and further comprising absorbent, liquid distribution, and breathable outer layers that protect skin health.

This application relates to the technical field of medical dressings, specifically to a preparation method of a dressing with a repair function, including: mixing citric acid-modified fucoidan and chitosan, adding water, heating and then performing ultrasonic oscillation, adding a crosslinking agent, heating while stirring to obtain a stock solution; mixing calendula extract, centella asiatica extract, dandelion extract, green tea extract, and honey, adding them to a high-speed disperser, adding water, after high-speed dispersion, adding them to the stock solution, continuing to stir, filtering, evaporating, standing to remove bubbles to obtain a precursor solution; soaking a porous scaffold in the precursor solution, allowing the precursor solution to penetrate into the pores of the porous scaffold through capillary action, and performing irradiation crosslinking and curing to obtain a dressing with a repair function. By selecting specific components for combination and using a specific preparation method, the prepared dressing with a repair function has good moisture retention, antibacterial properties, and mechanical strength while maintaining good wound repair function.

The invention discloses a graphene hyaluronic acid mask and a preparation method thereof.The mask is composed of a component A and a component B. The component A is prepared from, by weight, 0.1-0.5 part of biomass graphene; 30 to 38 parts of hyaluronic acid; 13-18 parts of a bletilla striata extract; 11 to 15 parts of a calendula extract; 6-13 parts of a ginseng extract; 3-7 parts of glycerol; 12-17 parts of a chrysanthemum extract; 20 to 25 parts of argireline; 2 to 5 parts of deionized water; 3 to 7 parts of propylene glycol; the component B is graphene film cloth, and the component B is used as a carrier for bearing the component A. The biomass graphene as the component A and the graphene mask cloth as the component B have good compatibility, the biomass graphene and the graphene mask cloth as the component B have good compatibility, and the loaded bletilla striata extract, calendula extract, ginseng extract and chrysanthemum extract are easy to absorb.

The invention provides a repairing composition containing PN and sodium hyaluronate as well as a preparation method and application of the repairing composition, and relates to the technical fields of medicines, medical instruments and cosmetics. The repairing composition is prepared from the following components in parts by weight: 1 to 4 parts of PN, 30 to 60 parts of sodium hyaluronate, 3 to 8 parts of palmitoyl tripeptide-5, 2.5 to 5 parts of radix notoginseng extract, 0.5 to 2 parts of radix astragali seu hedysari extract, 0.5 to 2 parts of recombinant human epidermal growth factor and 0.5 to 2 parts of calendula extract. The pseudo-ginseng extract is subjected to heating treatment by adopting an alkaline substance, so that dissolution of active ingredients is facilitated; the astragalus extract is subjected to decoction and microwave-assisted treatment, so that the content of astragalus polysaccharide and other components is increased; all the components interact with one another, so that the effects of remarkably promoting wound healing, resisting inflammation and improving skin acne pigmentation are achieved.

The invention belongs to the technical field of cosmetic preparation, and particularly relates to a plant extract composition for repairing sensitive skin and a preparation method of the plant extract composition. The chamomile extract, the purslane extract, the scutellaria baicalensis extract, the centella asiatica extract, the calendula extract, the salvia miltiorrhiza root extract and the witch hazel extract are specifically combined, and the raw materials can inhibit release of inflammatory factors and exert a higher anti-inflammatory effect; meanwhile, the natural active ingredients in the extract can fundamentally regulate the inflammatory response of the skin and enhance the elasticity and compactness of the skin, so that the damaged skin structure is favorably repaired, and the overall health state of the skin is improved; in addition, the composition is extracted from plants, is mild and does not cause additional stimulation to sensitive skin. Therefore, the plant extract composition provided by the invention not only has a good repairing effect, but also is green and safe.

The embodiments disclose a body balm including a composition of ingredients comprising organic shea butter in a predetermined range of concentration, organic jojoba oil in a predetermined range of concentration, organic vitamin E oil in a predetermined range of concentration, organic calendula oil in a predetermined range of concentration, organic sweet almond oil in a predetermined range of concentration, the organic lavender essential oil in a predetermined range of concentration, organic Palo Santo essential oil in a predetermined range of concentration and wherein the composition of ingredients is made up into of all organic vegan balm product types including a body balm, a body glaze, and body butter.

1. The name of the product of this design: packaging bottle (marigold). 2. Purpose of the product of this design: This product of this design is a packaging bottle for lotion. 3. The design key point of this appearance design product lies in the shape. 4. The picture or photo that best illustrates the design points: three-dimensional picture.

The invention discloses a disinfectant for in-vitro incubation of procambarus clarkii embryos and a preparation method and application thereof. The disinfectant comprises at least one of a first disinfectant, a second disinfectant and a third disinfectant, the first disinfectant comprises sodium chloride, trehalose, sodium dodecyl benzene sulfonate and water; the second disinfectant comprises at least one of an essential oil mixed solution, a six-herb mixed solution and a six-flower mixed solution; the essential oil mixed liquid comprises thyme essential oil, sage essential oil, blue eucalyptus essential oil, mint essential oil and water; the six-herb mixed solution comprises felwort, houttuynia cordata, caryopteris incana, humifuse euphorbia herb, liquorice, lavender and an ethanol solution; the mixed liquor of the six flowers comprises honeysuckle flowers, calendula flowers, flos florae, safflower, lilac flowers, rose flowers and an ethanol solution; the third disinfectant is prepared from polysorbate-80, astaxanthin, glycine and water. The disinfectant comprises the first disinfectant, the second disinfectant and the third disinfectant which are mutually promoted and have synergistic interaction, and the obtained disinfectant is non-toxic, harmless, green, environment-friendly, good in disinfection effect, good in embryo protection effect, good in stability, convenient to use, capable of replacing an existing formaldehyde disinfectant, high in hatching rate and good in emergence rate.

The invention discloses a composite dressing which comprises a hot-melt pressure-sensitive adhesive, a water-absorbing polymer material, a plant extract, a nano material, a transdermal absorption enhancer and a healing promoting agent, and the plant extract is selected from one or more of a leontopodium alpinum extract, an impatiens balsamina extract, tea tree essential oil, a calendula extract and a chamomile extract. According to the composite dressing based on the multi-effect composite plant extract, the leontopodium alpinum extract and the impatiens balsamina extract are compounded, the effect of the impatiens balsamina is amplified through compounding of the leontopodium alpinum, the adding amount of the impatiens balsamina is reduced, the content of the impatiens balsamina extract with high irritation is reduced, the irritation is reduced, and the effect of the impatiens balsamina is improved. Meanwhile, by compounding the leontopodium alpinum and the impatiens balsamina extract, the soothing effect can be achieved, and stimulation caused by the impatiens balsamina extract is weakened while the effect is not reduced; and a nano material is adopted as a carrier, so that the release of the extract is more sufficient, and the effect is obviously improved.

The invention discloses preparation of gleditsia sinensis polysaccharide and application of the gleditsia sinensis polysaccharide in products with functions of resisting oxidation and / or reducing blood sugar. According to the invention, Gleditsia sinensis Lam. Endosperm is used as a raw material, a green and efficient extraction technology is adopted to obtain purified Gleditsia sinensis Lam. Polysaccharide GSP-1, and the structure of the Gleditsia sinensis Lam. Polysaccharide GSP-1 is analyzed through high performance gel permeation chromatography, infrared spectroscopy, ion chromatography, gas chromatography-mass spectrometry and nuclear magnetic resonance spectroscopy. The GSP-1 has excellent antioxidation and hypoglycemic effects, promotes glucose consumption, promotes glucose metabolism, effectively improves insulin resistance, and has a positive promotion effect on regulating blood sugar and preventing and treating diabetes mellitus; the method has wide application prospects in the aspects of food processing, health care product development, functional food addition and the like for assisting in treating diabetes and controlling blood sugar, and has important significance in improving the added value of gleditsia sinensis, improving the scientific and technological innovation ability of agricultural products and driving industrial transformation and upgrading.

The invention relates to a body scrub cream and a preparation method thereof. The body scrub cream is prepared from the following raw materials in percentage by weight: 3%-8% of sodium methyl cocoyl taurate, 2%-8% of sodium lauroyl sarcosinate, 3%-7% of glycerol, 0.02%-0.07% of sodium citrate, 2%-5% of sunflower seed oil, 0.08%-0.35% of xanthan gum, 0.08%-0.35% of gellan gum, 0.03%-0.07% of disodium ethylene diamine tetraacetate, 0.8%-3% of apple fruit extract, 0.03%-0.08% of citric acid and the balance of water. The bath lotion is prepared from the following components in percentage by weight: 1.8%-3% of black walnut shell extract, 0.2%-0.6% of phenoxyethanol, 0.07%-0.13% of essence, 3%-9% of hydrated silica, 0.4%-0.9% of kiwi fruit extract and 0.4%-0.9% of calendula extract. According to the scheme provided by the invention, cutin can be mildly removed, the skin is kept moist and balanced, and the dull yellow skin is improved.

The invention relates to the technical field of cosmetics. The invention particularly relates to an active composition for skin wrinkle resistance and barrier repair, which is mainly characterized by comprising a leukocyte extract and a plant exosome, the plant exosomes are selected from two or more of ginseng, ginger, aloe, bidens pilosa, olive, green tea, centella asiatica, grape seeds, rosemary, turmeric, tremella fuciformis, calendula, scutellaria baicalensis, medlar and rose. The skin anti-wrinkle and barrier repairing active composition, the corresponding essence and the application can be used for improving wrinkles, increasing the skin water content, reducing transdermal water loss and improving the skin barrier function.

The present invention is directed to compositions and methods for ameliorating symptoms associated with inflammatory skin disorders involving applying a synergistic blend of plant-based actives containing: (1) a synergistic blend of at least: (a) Calendula officinalis stem cell extract; (b) Symphytum officinale extract; (c) a biotech-derived Haberlea rhodopensis extract; and (d) Padina pavonica thallus extract; and (2) at least one skin protectant active ingredient.

The invention relates to an anti-oxidation and anti-initial-aging herbal extract and a preparation method and application thereof.The preparation method comprises the steps that a herbal composition and a deep-eutectic solvent are mixed and extracted, and after solid-liquid separation, the herbal extract is obtained; the herbal composition comprises liquorice, pomegranate, calendula, spanishneedles herb and wild chrysanthemum flower, and ginseng can be added in a preferable scheme. The herbal extract provided by the invention is obtained by synergistically extracting herbaceous plants rich in flavones, polyphenols and triterpenoid saponins, and by virtue of the natural and safe characteristics of the herbaceous plants and through scientific compatibility, the obtained extract can delay senescence through multiple targets, so that the skin is rejuvenated.