The invention discloses a pediluvium composition and a preparing method thereof. The pediluvium composition is made of the following raw materials: ephedra, Cassia Twig, zanthoxylum husk, Lightyellow Sophora Root, dictamni cortex, Kadsura Root-bark, selinum japenious seed, Belvedere Fruit, anomalous wormwood, Garden Balsam Stem, ground pine, Homalomena occulta, Schizophragma integrifolium Oliv, hairy kind of sage, saposhnikovia, asarum, Chinese mugwort leaf, atractylis, Frankincense, nardostachyos, Astragalus root, pubescent angelica, Pangolin Scales, Nux Vomica, sapanwood, and cynanchum paniculatum. The pediluvium composition of the invention can be prepared as any kind of common patent medicine for external use. The pediluvium composition of the invention makes use of synergistic action of a variety of active components from Chinese herbal medicine so that the pediluvium composition has the functions of supplementing qi and nourishing the blood, freeing the channels and quickening the network vessels, dissipating cold and relieving pain, dispelling wind and eliminating dampness, quieting the spirit and sedating, and supplementing kidney quickening blood. The pediluvium composition can also alleviate the symptoms of fatigue and sub-health and prevent diseases effectively and efficiently.