2results about How to "Restore balance" patented technology

This invention discloses the application of a Cav3.2 inhibitor in the preparation of a drug for treating intervertebral disc degeneration. Z944 can block the activation level of Cav3.2 in nucleus pulposus cells, effectively alleviating lipid metabolism disorders and cellular biological behavior disorders induced by abnormal mechanical stress, and ultimately reducing intervertebral disc degeneration. This demonstrates that Z944 is a drug with clinical application potential, which can be used to alleviate the pain and burden of patients with low back pain and improve their quality of life.

The invention provides radish polysaccharide oral liquid with an auxiliary protection effect on chemical liver injury, and belongs to the technical field of prevention and treatment of chemical liver injury. The preparation method of the radish polysaccharide provided by the invention comprises the following steps: drying radishes, and crushing the dried radishes to obtain radish powder; mixing the radish powder with absolute ethyl alcohol, standing at 50 DEG C for 8 hours, and filtering with gauze to obtain filter residues; mixing the filter residues with water to obtain a mixture, mixing the mixture with cellulase, performing enzymolysis for 40-70 minutes at the temperature of 30-55 DEG C, taking filtrate, performing alcohol precipitation, collecting precipitates, adding water, performing redissolution, performing centrifugation, taking supernatant, and performing freeze drying to obtain the radish polysaccharide. According to the method for preparing the radish polysaccharide with the auxiliary protection effect on the chemical liver injury, provided by the invention, the high-content radish polysaccharide with the auxiliary protection effect on the alcoholic liver injury can be obtained from radishes. The radish polysaccharide oral liquid and the green radish polysaccharide oral liquid provided by the invention have a remarkable protection effect on acute liver injury caused by alcohol.